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| For further information please contact Nader Pourmand |
In order to quickly and inexpensively detect bioaffinity interactions we are developing a system for impedance-based readout of protein microarrays. When a target protein binds to the pre-functionalized probe surface, the impedance of the electrode-solution interface changes and this change is detected electrically over a range of mesurements frequencies. No labeling or special reagents are required, and detection can be performed in real-time without any optical components, making this system ideal for inexpensive point of care applications. Our eventual goal is to integrate the microarray electrodes on the top of a specialized impedance-measuring CMOS chip. This project is a collaborative effort between SGTC and the Stanford Center for Integrated Systems.