Description

This column shows the expression of genes during the cell cycle of the budding yeast S. cerevisiae.

Cells from a synchronous yeast culture were collected at 17 time points taken at 10 minute intervals, covering nearly 2 full cell cycles. By default, the column shows the ratio of gene expression at a specific cell cycle phase to expression of the gene overall. A gene that is more highly expressed in a cell cycle phase is colored red, and a less expressed gene is shown in green. The values are colored on a logarithmic scale. This coloring is standard, but is the opposite of what a naive user might expect: in this case, red means go and green means stop! Black indicates that a gene is neither over- nor under-expressed in the cell cycle phase. Uncolored boxes (white on most browsers) represent missing data.

Column Configuration

Several column configuration options are available on the Configuration page, which can be accessed via the configure button in the top menu.

Methods

The data in this column were collected as described in the paper Cho RJ et al. (1998), "A genome-wide transcriptional analysis of the mitotic cell cycle", Mol Cell. 1998 Jul;2(1):65-73.

Credits

Many thanks to Cho et al. for making the data available.