Description

The Stanford Human Promoters dataset was generated by Rick Myers' Lab at Stanford University and is described thoroughly in "Identification and Functional Characterization of Human Transcriptional Promoters."

Briefly, Full-length human cDNAs were aligned to the human genome sequence to predict putative starts of transcription. Roughly 500 bp of putative promoter sequence was then cloned into a reporter construct for 150 random promoters. More than 90% of these fragments had significant promoter activity in at least one of the cell types we tested.

The promoters highlighted in black have been experimentally confirmed as functional promoters, and the ones highlighted in gray are predicted and are in the process of being tested.

Any questions or comments, email nathant@stanford.edu or shelleyj@stanford.edu