Assembling and Annotating the Draft Human Genome

Table of Contents

Assembling and Annotating the Draft Human Genome

Long Term Research Goal

Triangulating on Regulatory Regions

PPT Slide

Improbizer Searches for Motifs

The Intronerator

Alt-splicing in Worm ESTs

let-2

Conserved ‘wobble’ bases

PPT Slide

The Call of the Human Genome

PPT Slide

Draft BACs Have Multiple Contigs

Preassembly Working Draft

Assembly Process

PPT Slide

Assembly Overall Results

A View After Assembly

Introducing the Browser

Chromosome 17

Band 17q21.2

Somewhere Near D17S932

BRCA1

Information on an Isoform

Picking Primers

PPT Slide

PPT Slide

The Mouse Genome Project

Mouse/Human Comparisons

DNA Chip Expression Data

DNA Chip Expression Data

Triangulating on Regulatory Regions?

Conclusions

Acknowledgments

Email: kent@biology.ucsc.edu

Home Page: www.cse.ucsc.edu/~kent

Other information:
3rd Year Talk: Assembling and Annotating the Human Genome