SAM-T2k-server, SAM-T06-server, SAM-T08-server Old servers serve as historical baseline for evaluating progress in prediction methods Kevin Karplus University of California, Santa Cruz karplus@soe.ucsc.edu Due to two years without funding, the group at UCSC did not test any new methods in CASP9, but only provided three old servers (SAM_T02, SAM_T06, and SAM_T08) for historical comparisons. Note that the SAM_T08 server is essentially the same as the SAM_T08_server in CASP8, not even including improvements using in SAM_T08_human predictions in CASP8. The databases searched by these three servers have been kept up to date, but the methods have not changed (except in small unavoidable ways as some software was broken by changes to the server compilers or operating systems, and had to be replaced by newer versions that would run on the current system). Thus the servers represent a fairly stable baseline for judging the difficulty of targets, which is important for determining whether there has been progress in other methods. Unless we get some funding for protein structure prediction in the next year, we will not be participating in future CASP experiments at all, and will not be doing further work in protein structure prediction.