PFRMAT SS TARGET T0640 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0640.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0640.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0640.t04.str2.rdb (weight 1.54758) METHOD T0640.t04.alpha.rdb (weight 0.659012) METHOD T0640.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0640.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0640.t2k.str2.rdb (weight 1.54758) METHOD T0640.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0640.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 22.1141 METHOD METHOD ============================================ METHOD Comments from T0640.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 22.1141 METHOD METHOD ============================================ METHOD Comments from T0640.t04.str2.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 22.1141 METHOD METHOD ============================================ METHOD Comments from T0640.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 22.1141 METHOD METHOD ============================================ METHOD Comments from T0640.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 6722 METHOD METHOD ============================================ METHOD Comments from T0640.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 6722 METHOD METHOD ============================================ METHOD Comments from T0640.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 6722 METHOD METHOD ============================================ METHOD Comments from T0640.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0640 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0640.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 6722 METHOD METHOD ============================================ MODEL 1 M C 0.86 S C 0.76 L C 0.59 E C 0.63 K C 0.68 Q C 0.83 K C 0.91 G C 0.68 L E 0.84 A E 0.92 I E 0.92 I E 0.87 T E 0.58 G C 0.74 A C 0.76 S C 0.69 Q C 0.63 G H 0.64 I H 0.91 G H 0.95 A H 0.96 V H 0.96 I H 0.96 A H 0.96 A H 0.96 G H 0.96 L H 0.95 A H 0.94 T H 0.84 D C 0.68 G C 0.94 Y C 0.90 R E 0.52 V E 0.93 V E 0.93 L E 0.93 I E 0.88 A E 0.63 R C 0.83 S C 0.88 K H 0.75 Q H 0.86 N H 0.90 L H 0.94 E H 0.94 K H 0.95 V H 0.95 H H 0.95 D H 0.95 E H 0.94 I H 0.92 M H 0.90 R H 0.84 S H 0.72 N H 0.52 K C 0.61 H C 0.68 V C 0.84 Q C 0.82 E C 0.53 P E 0.72 I E 0.86 V E 0.91 L E 0.85 P E 0.76 L E 0.52 D C 0.64 I C 0.75 T C 0.84 D C 0.86 C H 0.85 T H 0.90 K H 0.93 A H 0.95 D H 0.95 T H 0.95 E H 0.96 I H 0.96 K H 0.95 D H 0.95 I H 0.95 H H 0.93 Q H 0.92 K H 0.83 Y C 0.54 G C 0.90 A C 0.84 V C 0.66 D C 0.54 I E 0.91 L E 0.92 V E 0.90 N E 0.79 A C 0.63 A C 0.72 A C 0.63 M C 0.56 F C 0.66 M C 0.75 D C 0.81 G C 0.84 S C 0.75 L C 0.73 S C 0.73 E C 0.83 P C 0.90 V H 0.90 D H 0.93 N H 0.93 F H 0.94 R H 0.94 K H 0.93 I H 0.93 M H 0.92 E H 0.90 I H 0.90 N H 0.84 V H 0.90 I H 0.92 A H 0.94 Q H 0.95 Y H 0.96 G H 0.96 I H 0.95 L H 0.95 K H 0.94 T H 0.91 V H 0.88 T H 0.89 E H 0.93 I H 0.94 M H 0.94 K H 0.92 V H 0.81 Q C 0.56 K C 0.88 N C 0.90 G C 0.72 Y E 0.74 I E 0.92 F E 0.90 N E 0.86 V E 0.59 A C 0.52 S C 0.54 R H 0.45 A H 0.49 A C 0.44 K C 0.51 Y C 0.61 G C 0.70 F C 0.83 A C 0.79 D C 0.80 G C 0.56 G H 0.47 I H 0.71 Y H 0.82 G H 0.88 S H 0.91 T H 0.94 K H 0.96 F H 0.96 A H 0.96 L H 0.96 L H 0.96 G H 0.95 L H 0.95 A H 0.96 E H 0.96 S H 0.96 L H 0.95 Y H 0.94 R H 0.94 E H 0.90 L H 0.86 A H 0.73 P H 0.63 L C 0.74 G C 0.90 I C 0.60 R E 0.82 V E 0.89 T E 0.88 T E 0.91 L E 0.87 C E 0.68 P C 0.63 G C 0.80 W C 0.67 V C 0.61 N C 0.65 T C 0.71 D H 0.65 M H 0.72 A H 0.74 K H 0.64 K H 0.56 A C 0.51 G C 0.71 T C 0.70 P C 0.73 F C 0.79 K C 0.78 D C 0.67 E C 0.68 E C 0.69 M C 0.81 I C 0.87 Q C 0.90 P H 0.88 D H 0.90 D H 0.92 L H 0.94 L H 0.94 N H 0.95 T H 0.96 I H 0.96 R H 0.95 C H 0.93 L H 0.86 L H 0.66 N C 0.70 L C 0.72 S H 0.50 E H 0.51 N C 0.47 V C 0.50 C C 0.49 I C 0.64 K C 0.72 D E 0.49 I E 0.81 V E 0.87 F E 0.86 E E 0.68 M C 0.73 K C 0.86 K C 0.78 S E 0.53 I E 0.75 I E 0.69 E E 0.53 G C 0.64 H C 0.61 H C 0.57 H C 0.59 H C 0.70 H C 0.80 H C 0.91 END