PFRMAT SS TARGET T0627 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0627.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0627.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0627.t04.str2.rdb (weight 1.54758) METHOD T0627.t04.alpha.rdb (weight 0.659012) METHOD T0627.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0627.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0627.t2k.str2.rdb (weight 1.54758) METHOD T0627.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0627.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1054 METHOD METHOD ============================================ METHOD Comments from T0627.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1054 METHOD METHOD ============================================ METHOD Comments from T0627.t04.str2.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1054 METHOD METHOD ============================================ METHOD Comments from T0627.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1054 METHOD METHOD ============================================ METHOD Comments from T0627.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 45 METHOD METHOD ============================================ METHOD Comments from T0627.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 45 METHOD METHOD ============================================ METHOD Comments from T0627.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 45 METHOD METHOD ============================================ METHOD Comments from T0627.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0627 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0627.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 45 METHOD METHOD ============================================ MODEL 1 M C 0.87 I C 0.76 D C 0.64 T C 0.50 F H 0.48 E H 0.44 R C 0.47 T C 0.60 G C 0.76 P C 0.68 L C 0.47 M C 0.41 E C 0.43 A C 0.60 S C 0.77 S C 0.79 Y C 0.84 P H 0.79 A H 0.92 W H 0.94 A H 0.95 Q H 0.95 Q H 0.95 L H 0.94 I H 0.93 N H 0.88 D H 0.71 C H 0.62 S H 0.50 P H 0.88 A H 0.92 K H 0.92 A H 0.91 R H 0.88 V H 0.82 V H 0.64 E C 0.54 H C 0.67 E H 0.89 L H 0.93 Y H 0.94 Q H 0.93 Q H 0.92 M H 0.87 R H 0.75 D C 0.67 A C 0.89 K C 0.88 L C 0.78 S C 0.92 P H 0.92 Q H 0.95 I H 0.95 M H 0.95 R H 0.95 Q H 0.95 Y H 0.94 L H 0.92 I H 0.90 G H 0.83 G H 0.78 W H 0.86 P H 0.90 V H 0.92 V H 0.93 E H 0.91 Q H 0.83 F H 0.83 A H 0.92 V H 0.95 Y H 0.95 M H 0.94 A H 0.93 K H 0.93 N H 0.91 L H 0.87 T H 0.67 K C 0.52 T C 0.74 R C 0.69 F C 0.66 G C 0.58 R C 0.65 H C 0.67 P H 0.49 G C 0.53 E H 0.74 D H 0.90 M H 0.93 A H 0.94 R H 0.95 R H 0.94 W H 0.93 L H 0.92 M H 0.90 R H 0.85 N H 0.73 I H 0.68 R H 0.63 V H 0.59 E H 0.57 L H 0.67 N H 0.60 H H 0.71 A H 0.92 D H 0.94 Y H 0.95 W H 0.95 V H 0.96 N H 0.96 W H 0.96 C H 0.95 A H 0.94 A H 0.87 H C 0.50 D C 0.92 V C 0.90 T C 0.92 L H 0.91 E H 0.93 D H 0.94 L H 0.93 H H 0.85 D H 0.53 Q C 0.77 R C 0.86 V C 0.87 A C 0.85 P H 0.90 E H 0.93 L H 0.94 H H 0.95 A H 0.95 L H 0.95 S H 0.95 H H 0.94 W H 0.93 C H 0.92 W H 0.90 Q H 0.86 T H 0.71 S C 0.57 S C 0.71 S C 0.69 D C 0.75 S C 0.58 L H 0.93 A H 0.95 V H 0.95 A H 0.95 M H 0.95 A H 0.95 A H 0.93 T H 0.92 N H 0.91 Y H 0.92 A H 0.90 I H 0.89 E H 0.82 G H 0.65 A H 0.58 T H 0.61 G H 0.79 E H 0.89 W H 0.90 S H 0.90 A H 0.86 V H 0.82 V H 0.77 C H 0.70 S H 0.62 T H 0.47 G H 0.53 V H 0.51 Y H 0.51 A H 0.44 E C 0.50 A C 0.69 F C 0.79 A C 0.76 E C 0.52 E C 0.54 T C 0.60 R C 0.68 K H 0.72 K H 0.90 S H 0.93 M H 0.95 K H 0.96 W H 0.95 L H 0.95 K H 0.95 M H 0.93 H H 0.86 A H 0.75 Q H 0.61 Y H 0.61 D C 0.53 D C 0.51 A C 0.50 H C 0.67 P H 0.77 W H 0.88 E H 0.91 A H 0.94 L H 0.95 E H 0.95 I H 0.96 I H 0.96 C H 0.95 T H 0.94 L H 0.89 V H 0.70 G C 0.62 N C 0.77 K C 0.86 P C 0.76 S C 0.69 L H 0.87 Q H 0.91 L H 0.93 Q H 0.95 A H 0.96 E H 0.96 L H 0.96 R H 0.96 Q H 0.96 A H 0.96 V H 0.96 T H 0.95 K H 0.94 S H 0.95 Y H 0.95 D H 0.95 Y H 0.95 M H 0.95 Y H 0.95 L H 0.94 F H 0.93 L H 0.93 E H 0.90 R H 0.80 C H 0.62 I C 0.52 Q C 0.72 L C 0.53 D C 0.54 K C 0.53 V C 0.63 K C 0.68 S C 0.71 P C 0.65 R C 0.61 G C 0.47 R E 0.48 V E 0.57 A E 0.58 A E 0.60 L E 0.53 E C 0.60 M C 0.91 END