PFRMAT SS TARGET T0578 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0578.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0578.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0578.t04.str2.rdb (weight 1.54758) METHOD T0578.t04.alpha.rdb (weight 0.659012) METHOD T0578.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0578.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0578.t2k.str2.rdb (weight 1.54758) METHOD T0578.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0578.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 7.82799 METHOD METHOD ============================================ METHOD Comments from T0578.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 7.82799 METHOD METHOD ============================================ METHOD Comments from T0578.t04.str2.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 7.82799 METHOD METHOD ============================================ METHOD Comments from T0578.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 7.82799 METHOD METHOD ============================================ METHOD Comments from T0578.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ METHOD Comments from T0578.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ METHOD Comments from T0578.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ METHOD Comments from T0578.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0578 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0578.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 28 METHOD METHOD ============================================ MODEL 1 S C 0.67 N H 0.62 A H 0.73 M H 0.75 K H 0.76 K H 0.71 A H 0.66 T C 0.61 M H 0.71 L H 0.91 T H 0.93 Y H 0.94 L H 0.94 E H 0.94 E H 0.94 Q H 0.93 L H 0.89 E H 0.83 K H 0.66 H C 0.64 L C 0.79 G C 0.82 D C 0.81 Y C 0.67 E C 0.49 V E 0.69 G E 0.75 L E 0.67 D E 0.53 W C 0.61 D C 0.70 R C 0.75 K C 0.78 N C 0.79 H C 0.65 T E 0.76 I E 0.90 E E 0.92 V E 0.92 I E 0.93 V E 0.93 R E 0.93 L E 0.92 Y E 0.91 A E 0.86 E E 0.58 N C 0.64 N C 0.70 E C 0.73 Q C 0.53 V E 0.55 A E 0.84 I E 0.85 D E 0.82 D C 0.55 V C 0.75 D C 0.84 G C 0.79 T C 0.56 L E 0.63 S C 0.76 E C 0.78 E C 0.82 E C 0.75 F C 0.48 I E 0.66 E E 0.76 F E 0.73 E E 0.61 D E 0.64 G E 0.82 L E 0.88 L E 0.89 F E 0.82 Y E 0.58 N C 0.74 P C 0.70 Q C 0.64 K C 0.54 S C 0.72 V C 0.66 V C 0.64 D C 0.80 D H 0.62 E H 0.54 E C 0.48 Y C 0.51 L E 0.65 V E 0.81 T E 0.82 I E 0.73 P E 0.50 Y C 0.77 E C 0.78 G C 0.76 K C 0.68 K C 0.75 G C 0.82 L C 0.71 R C 0.56 K H 0.94 A H 0.95 V H 0.95 L H 0.96 D H 0.96 G H 0.96 F H 0.96 I H 0.96 H H 0.96 Y H 0.96 L H 0.96 K H 0.96 V H 0.96 V H 0.95 L H 0.94 D H 0.89 E H 0.60 G C 0.66 Q H 0.56 S H 0.71 D H 0.77 L H 0.84 L H 0.84 D H 0.79 F H 0.63 L C 0.54 S C 0.78 D C 0.88 E C 0.75 T C 0.72 A C 0.66 E C 0.66 V E 0.63 F E 0.78 E E 0.87 L E 0.83 H E 0.76 W C 0.57 E C 0.86 P H 0.86 A H 0.92 D H 0.93 F H 0.94 E H 0.94 A H 0.92 M H 0.91 I H 0.90 K H 0.85 K H 0.77 V H 0.69 A H 0.74 E H 0.72 T H 0.58 E C 0.49 K C 0.67 E C 0.72 Q C 0.72 W C 0.76 I C 0.86 A C 0.83 Y C 0.81 P C 0.82 S C 0.80 Y C 0.91 END