PFRMAT SS TARGET T0573 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0573.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0573.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0573.t04.str2.rdb (weight 1.54758) METHOD T0573.t04.alpha.rdb (weight 0.659012) METHOD T0573.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0573.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0573.t2k.str2.rdb (weight 1.54758) METHOD T0573.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0573.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 276.896 METHOD METHOD ============================================ METHOD Comments from T0573.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 276.896 METHOD METHOD ============================================ METHOD Comments from T0573.t04.str2.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 276.896 METHOD METHOD ============================================ METHOD Comments from T0573.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 276.896 METHOD METHOD ============================================ METHOD Comments from T0573.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2495 METHOD METHOD ============================================ METHOD Comments from T0573.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2495 METHOD METHOD ============================================ METHOD Comments from T0573.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2495 METHOD METHOD ============================================ METHOD Comments from T0573.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0573 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0573.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2495 METHOD METHOD ============================================ MODEL 1 M C 0.85 S C 0.76 T C 0.68 S C 0.55 A E 0.79 I E 0.82 D E 0.64 P C 0.58 V C 0.56 S H 0.56 F C 0.56 S C 0.71 L C 0.80 Y C 0.82 A C 0.73 K H 0.56 D H 0.62 F H 0.79 T H 0.92 R H 0.95 F H 0.95 A H 0.96 Q H 0.96 E H 0.96 L H 0.96 G H 0.96 A H 0.95 S H 0.94 F H 0.93 E H 0.88 R H 0.74 Y C 0.64 G C 0.87 F C 0.52 A E 0.78 V E 0.88 L E 0.87 S E 0.74 D C 0.48 Y C 0.79 D C 0.83 L C 0.84 D C 0.91 Q H 0.91 A H 0.94 R H 0.95 I H 0.96 D H 0.95 A H 0.95 A H 0.95 V H 0.96 D H 0.95 S H 0.95 A H 0.95 K H 0.93 A H 0.90 F H 0.83 F H 0.66 A C 0.58 L C 0.86 P C 0.89 V H 0.87 E H 0.89 T H 0.91 K H 0.90 K H 0.86 Q H 0.81 Y H 0.68 A H 0.50 G C 0.61 V C 0.71 K C 0.75 G C 0.75 G C 0.74 A C 0.71 R C 0.65 G C 0.57 Y C 0.48 I E 0.48 P C 0.49 F C 0.56 G C 0.59 V C 0.57 E C 0.54 T C 0.51 A C 0.53 K C 0.62 G C 0.68 A C 0.72 D C 0.73 H C 0.70 Y C 0.64 D C 0.62 L H 0.47 K H 0.49 E H 0.49 F H 0.42 W C 0.43 H C 0.52 M C 0.51 G C 0.57 R C 0.56 D C 0.59 L C 0.65 P C 0.64 P C 0.63 G C 0.66 H C 0.67 R C 0.69 F C 0.66 R C 0.61 A C 0.61 H C 0.65 M C 0.68 A C 0.72 D C 0.70 N C 0.71 V C 0.69 W C 0.74 P C 0.65 A C 0.65 E C 0.74 I C 0.75 P H 0.70 A H 0.70 F H 0.84 K H 0.93 H H 0.95 D H 0.95 V H 0.95 S H 0.96 W H 0.96 L H 0.96 Y H 0.96 N H 0.96 S H 0.95 L H 0.95 D H 0.96 G H 0.95 M H 0.95 G H 0.96 G H 0.96 K H 0.96 V H 0.96 L H 0.96 E H 0.96 A H 0.96 I H 0.96 A H 0.96 T H 0.94 Y H 0.85 L C 0.52 K C 0.91 L C 0.94 E C 0.92 R H 0.67 D H 0.73 F H 0.80 F H 0.79 K H 0.79 P H 0.75 T H 0.64 V C 0.55 Q C 0.74 D C 0.83 G C 0.79 N C 0.77 S C 0.48 V E 0.81 L E 0.87 R E 0.88 L E 0.83 L E 0.70 H E 0.56 Y C 0.64 P C 0.73 P C 0.80 I C 0.84 P C 0.85 K C 0.87 D C 0.81 A C 0.77 T C 0.73 G C 0.65 V C 0.54 R C 0.58 A C 0.59 G C 0.68 A C 0.69 H C 0.72 G C 0.74 D C 0.80 I C 0.73 N C 0.74 T E 0.40 I E 0.65 T E 0.75 L E 0.79 L E 0.78 L E 0.67 G C 0.51 A C 0.72 E C 0.76 E C 0.74 G C 0.70 G C 0.55 L E 0.72 E E 0.87 V E 0.89 L E 0.87 D C 0.54 R C 0.86 D C 0.93 G C 0.92 Q C 0.53 W E 0.89 L E 0.87 P E 0.87 I E 0.62 N C 0.50 P C 0.56 P C 0.79 P C 0.89 G C 0.92 C C 0.49 L E 0.86 V E 0.92 I E 0.87 N E 0.62 I C 0.48 G H 0.77 D H 0.90 M H 0.94 L H 0.95 E H 0.94 R H 0.92 L H 0.87 T H 0.66 N C 0.73 N C 0.89 V C 0.76 L C 0.58 P C 0.62 S C 0.61 T C 0.56 V C 0.47 H E 0.56 R E 0.71 V E 0.77 V E 0.72 N C 0.50 P C 0.73 P C 0.71 P C 0.62 E C 0.60 R C 0.69 R C 0.72 G C 0.76 V C 0.76 P C 0.69 R C 0.48 Y E 0.59 S E 0.68 T E 0.71 P E 0.66 F E 0.66 F E 0.64 L E 0.51 H C 0.67 F C 0.78 A C 0.81 S C 0.78 D C 0.79 Y C 0.51 E E 0.70 I E 0.70 K E 0.54 T C 0.66 L C 0.68 Q H 0.63 N H 0.66 C H 0.54 V C 0.70 T C 0.84 A C 0.76 E C 0.79 N C 0.82 P C 0.74 D C 0.68 R C 0.61 Y C 0.80 P C 0.84 E C 0.77 S C 0.59 I C 0.75 T H 0.87 A H 0.94 D H 0.95 E H 0.95 F H 0.95 L H 0.94 Q H 0.93 Q H 0.92 R H 0.88 L H 0.81 R H 0.63 E H 0.48 I C 0.64 K C 0.78 L C 0.86 A C 0.89 END