PFRMAT SS TARGET T0557 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0557.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0557.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0557.t04.str2.rdb (weight 1.54758) METHOD T0557.t04.alpha.rdb (weight 0.659012) METHOD T0557.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0557.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0557.t2k.str2.rdb (weight 1.54758) METHOD T0557.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0557.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 876 METHOD METHOD ============================================ METHOD Comments from T0557.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 876 METHOD METHOD ============================================ METHOD Comments from T0557.t04.str2.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 876 METHOD METHOD ============================================ METHOD Comments from T0557.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 876 METHOD METHOD ============================================ METHOD Comments from T0557.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 164 METHOD METHOD ============================================ METHOD Comments from T0557.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 164 METHOD METHOD ============================================ METHOD Comments from T0557.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 164 METHOD METHOD ============================================ METHOD Comments from T0557.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0557 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0557.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 164 METHOD METHOD ============================================ MODEL 1 M C 0.86 R C 0.67 S H 0.59 A H 0.88 T H 0.92 D H 0.94 L H 0.95 L H 0.95 D H 0.95 E H 0.94 L H 0.93 N H 0.88 A H 0.69 V C 0.67 D C 0.87 E C 0.81 S C 0.73 A C 0.59 R E 0.45 I E 0.57 E E 0.65 A E 0.62 K E 0.50 R C 0.39 A C 0.64 S C 0.83 D C 0.87 M C 0.86 G C 0.77 K H 0.56 S H 0.60 V H 0.79 M H 0.75 E H 0.77 T H 0.75 V H 0.75 I H 0.73 A H 0.70 F H 0.52 A C 0.40 N C 0.68 E C 0.82 P C 0.85 G C 0.87 L C 0.81 D C 0.82 G C 0.77 G C 0.62 Y E 0.82 L E 0.91 L E 0.92 L E 0.88 G E 0.85 V E 0.78 D E 0.66 W C 0.54 A C 0.76 I C 0.85 N C 0.83 D E 0.57 K E 0.79 G E 0.77 D E 0.68 T E 0.55 V C 0.52 Y C 0.63 R C 0.75 P C 0.77 V C 0.78 G C 0.76 L C 0.48 P H 0.58 D H 0.62 P H 0.85 D H 0.89 K H 0.92 V H 0.93 Q H 0.93 R H 0.92 D H 0.89 L H 0.87 A H 0.79 S H 0.66 Q H 0.62 C H 0.62 A H 0.59 S H 0.52 M C 0.55 L C 0.66 N C 0.81 V C 0.79 A C 0.79 L C 0.75 R C 0.77 P C 0.72 E C 0.57 M E 0.67 Q E 0.83 L E 0.87 E E 0.88 Q E 0.84 V E 0.61 G C 0.86 G C 0.91 K E 0.51 T E 0.87 L E 0.93 L E 0.93 V E 0.93 V E 0.91 Y E 0.87 V E 0.60 P C 0.73 E C 0.82 A C 0.84 D C 0.86 V C 0.66 T C 0.74 H C 0.75 K C 0.74 P C 0.64 I E 0.77 Y E 0.85 K E 0.77 K E 0.58 A C 0.65 T C 0.80 G C 0.80 L C 0.74 P C 0.70 G C 0.77 G C 0.68 A E 0.63 Y E 0.84 R E 0.84 R E 0.75 I C 0.48 G C 0.83 S C 0.87 S C 0.82 D C 0.76 Q C 0.64 R C 0.60 C C 0.78 V C 0.92 END