PFRMAT SS TARGET T0550 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0550.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0550.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0550.t04.str2.rdb (weight 1.54758) METHOD T0550.t04.alpha.rdb (weight 0.659012) METHOD T0550.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0550.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0550.t2k.str2.rdb (weight 1.54758) METHOD T0550.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0550.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 604 METHOD METHOD ============================================ METHOD Comments from T0550.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 604 METHOD METHOD ============================================ METHOD Comments from T0550.t04.str2.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 604 METHOD METHOD ============================================ METHOD Comments from T0550.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 604 METHOD METHOD ============================================ METHOD Comments from T0550.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 41 METHOD METHOD ============================================ METHOD Comments from T0550.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 41 METHOD METHOD ============================================ METHOD Comments from T0550.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 41 METHOD METHOD ============================================ METHOD Comments from T0550.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0550 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0550.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 41 METHOD METHOD ============================================ MODEL 1 M C 0.67 K H 0.70 N H 0.85 I H 0.91 Y H 0.94 I H 0.95 Y H 0.96 L H 0.96 S H 0.96 L H 0.96 L H 0.96 A H 0.96 V H 0.96 I H 0.95 V H 0.93 L H 0.87 G H 0.70 T C 0.51 A C 0.72 C C 0.79 N C 0.79 N C 0.51 E H 0.67 W H 0.66 E H 0.72 D H 0.80 E H 0.78 Q H 0.73 Y H 0.66 E H 0.56 Q H 0.43 Y E 0.47 V E 0.60 S E 0.66 F E 0.65 K E 0.59 A C 0.50 P C 0.61 I C 0.67 A C 0.71 S C 0.71 G C 0.70 S C 0.60 D C 0.53 G E 0.54 V E 0.72 T E 0.78 T E 0.83 I E 0.86 Y E 0.88 V E 0.87 R E 0.86 Y E 0.82 K C 0.51 D C 0.84 N C 0.92 G C 0.88 K E 0.52 V E 0.86 T E 0.89 Y E 0.90 Q E 0.90 L E 0.89 P E 0.88 I E 0.91 I E 0.91 V E 0.88 S E 0.64 G C 0.57 S C 0.64 T C 0.68 V C 0.73 N C 0.80 S C 0.78 Q C 0.78 D C 0.70 R E 0.63 D E 0.84 I E 0.89 H E 0.90 I E 0.87 A E 0.81 V E 0.50 D C 0.83 K H 0.64 D H 0.67 T H 0.86 L H 0.91 K H 0.93 T H 0.93 L H 0.92 N H 0.88 I H 0.85 E H 0.80 R H 0.66 F C 0.50 S C 0.55 L C 0.56 Y C 0.69 R C 0.54 P C 0.48 E H 0.46 L C 0.46 W C 0.45 Y E 0.44 T E 0.52 E E 0.46 M C 0.65 E C 0.73 E C 0.54 D C 0.55 K C 0.53 Y E 0.50 E E 0.59 F C 0.55 P C 0.75 E C 0.77 T C 0.57 V E 0.69 H E 0.81 I E 0.66 P C 0.75 A C 0.88 G C 0.89 S C 0.68 C E 0.61 V E 0.71 E E 0.75 L E 0.80 L E 0.76 N E 0.71 I E 0.78 D E 0.81 F E 0.73 N C 0.55 L C 0.66 Q C 0.73 D C 0.72 I C 0.72 D C 0.78 M C 0.70 L C 0.70 E C 0.67 K C 0.63 W E 0.63 V E 0.74 L E 0.67 P E 0.66 L E 0.83 T E 0.88 I E 0.88 V E 0.72 D C 0.57 D C 0.82 G C 0.85 S C 0.83 Y C 0.77 A C 0.60 Y E 0.50 Q E 0.52 S C 0.49 H C 0.72 P C 0.69 R C 0.73 K C 0.69 N C 0.64 Y C 0.40 A E 0.59 K E 0.71 A E 0.76 L E 0.75 L E 0.72 K E 0.70 V E 0.66 V E 0.58 P E 0.57 F E 0.50 N C 0.61 N C 0.72 Y C 0.76 S C 0.70 G C 0.70 S C 0.56 Y E 0.47 T C 0.58 A C 0.60 S C 0.56 S E 0.47 M E 0.66 K E 0.79 V E 0.83 Y E 0.83 T E 0.81 Y E 0.66 I C 0.56 N C 0.73 G C 0.80 K C 0.83 P C 0.79 D C 0.75 T C 0.76 N C 0.73 A C 0.61 R E 0.54 T E 0.65 T E 0.71 D E 0.73 K E 0.80 R E 0.81 T E 0.81 G E 0.77 Y E 0.80 V E 0.82 V E 0.72 D C 0.51 N C 0.74 N C 0.74 S E 0.63 I E 0.81 F E 0.88 F E 0.85 Y E 0.80 A E 0.65 G E 0.53 L E 0.58 I E 0.55 N C 0.53 E H 0.46 D H 0.48 M H 0.55 D H 0.62 K H 0.56 D H 0.56 M H 0.47 R C 0.55 K C 0.65 K C 0.57 Y E 0.72 K E 0.84 I E 0.88 N E 0.89 V E 0.83 H E 0.63 F C 0.69 K C 0.84 E C 0.82 D C 0.79 G C 0.66 T E 0.63 L E 0.82 D E 0.86 M E 0.83 K E 0.80 Q E 0.71 D E 0.56 D C 0.61 P C 0.74 S C 0.78 N C 0.78 E C 0.76 M C 0.58 E C 0.48 F E 0.65 E E 0.66 L E 0.59 I C 0.59 G C 0.78 T C 0.81 P C 0.74 T C 0.58 Y E 0.62 S E 0.71 S E 0.75 T E 0.72 S E 0.70 V E 0.68 M E 0.53 D C 0.77 A C 0.81 T C 0.85 R C 0.83 P C 0.68 Y E 0.53 L E 0.74 E E 0.81 R E 0.82 R E 0.87 Y E 0.90 V E 0.90 Q E 0.90 I E 0.83 M E 0.68 F C 0.49 E E 0.49 Y E 0.49 D C 0.51 F C 0.56 Q C 0.65 D C 0.66 F C 0.61 T C 0.60 Y C 0.59 G C 0.77 G C 0.83 S C 0.87 G C 0.83 T C 0.68 E C 0.56 V C 0.50 I E 0.59 P E 0.67 I E 0.77 K E 0.78 Y E 0.84 R E 0.90 V E 0.90 A E 0.84 G E 0.82 S E 0.86 M E 0.86 T E 0.86 L E 0.83 L E 0.84 R E 0.69 N E 0.54 I C 0.48 N C 0.62 T C 0.65 Q C 0.64 I C 0.75 P C 0.86 D C 0.79 E H 0.71 D H 0.79 Q H 0.74 Q H 0.69 I H 0.56 E C 0.53 W C 0.89 END