PFRMAT SS TARGET T0517 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0517.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0517.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0517.t04.str2.rdb (weight 1.54758) METHOD T0517.t04.alpha.rdb (weight 0.659012) METHOD T0517.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0517.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0517.t2k.str2.rdb (weight 1.54758) METHOD T0517.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0517.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 156.387 METHOD METHOD ============================================ METHOD Comments from T0517.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 156.387 METHOD METHOD ============================================ METHOD Comments from T0517.t04.str2.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 156.387 METHOD METHOD ============================================ METHOD Comments from T0517.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 156.387 METHOD METHOD ============================================ METHOD Comments from T0517.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 223 METHOD METHOD ============================================ METHOD Comments from T0517.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 223 METHOD METHOD ============================================ METHOD Comments from T0517.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 223 METHOD METHOD ============================================ METHOD Comments from T0517.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0517 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0517.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 223 METHOD METHOD ============================================ MODEL 1 M C 0.85 E C 0.80 N C 0.77 K C 0.75 K C 0.67 M E 0.69 N E 0.88 L E 0.93 L E 0.92 L E 0.87 F E 0.63 S C 0.78 G C 0.90 D C 0.84 Y H 0.84 D H 0.88 K H 0.91 A H 0.93 L H 0.94 A H 0.95 S H 0.96 L H 0.96 I H 0.96 I H 0.96 A H 0.96 N H 0.96 A H 0.96 A H 0.96 R H 0.94 E H 0.89 M C 0.64 E C 0.95 I C 0.91 E E 0.51 V E 0.84 T E 0.91 I E 0.93 F E 0.93 C E 0.89 A E 0.63 F C 0.51 W H 0.59 G H 0.73 L H 0.86 L H 0.87 L H 0.84 L H 0.77 R H 0.64 D C 0.51 P C 0.67 E C 0.66 K C 0.61 A C 0.58 S C 0.65 Q C 0.69 E C 0.70 D C 0.68 K C 0.69 S C 0.68 L C 0.60 Y C 0.57 E C 0.51 Q H 0.59 A H 0.58 F H 0.55 S H 0.53 S H 0.48 L C 0.56 T C 0.73 P C 0.79 R C 0.77 E C 0.78 A C 0.71 E C 0.64 E C 0.59 L C 0.65 P C 0.62 L C 0.59 S C 0.58 K C 0.67 M C 0.67 N C 0.77 L C 0.66 G C 0.60 G H 0.55 I H 0.67 G H 0.78 K H 0.95 K H 0.96 M H 0.96 L H 0.96 L H 0.96 E H 0.96 M H 0.95 M H 0.94 K H 0.93 E H 0.84 E C 0.57 K C 0.92 A C 0.92 P C 0.89 K C 0.84 L H 0.90 S H 0.95 D H 0.95 L H 0.95 L H 0.96 S H 0.96 G H 0.96 A H 0.95 R H 0.94 K H 0.87 K C 0.66 E C 0.94 V C 0.88 K E 0.65 F E 0.91 Y E 0.91 A E 0.87 C E 0.51 Q C 0.44 L H 0.56 S H 0.67 V H 0.77 E H 0.81 I H 0.75 M C 0.60 G C 0.91 F C 0.91 K C 0.91 K H 0.81 E H 0.85 E H 0.85 L H 0.63 F H 0.49 P C 0.51 E C 0.67 V C 0.74 Q C 0.59 I E 0.55 M E 0.44 D C 0.43 V H 0.86 K H 0.93 E H 0.94 Y H 0.93 L H 0.93 K H 0.91 N H 0.87 A H 0.82 L H 0.65 E C 0.60 S C 0.78 D C 0.88 L C 0.50 Q E 0.80 L E 0.86 F E 0.78 I C 0.69 END