PFRMAT SS TARGET T0514 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0514.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0514.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0514.t04.str2.rdb (weight 1.54758) METHOD T0514.t04.alpha.rdb (weight 0.659012) METHOD T0514.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0514.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0514.t2k.str2.rdb (weight 1.54758) METHOD T0514.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0514.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 205 METHOD METHOD ============================================ METHOD Comments from T0514.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 205 METHOD METHOD ============================================ METHOD Comments from T0514.t04.str2.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 205 METHOD METHOD ============================================ METHOD Comments from T0514.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 205 METHOD METHOD ============================================ METHOD Comments from T0514.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 84 METHOD METHOD ============================================ METHOD Comments from T0514.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 84 METHOD METHOD ============================================ METHOD Comments from T0514.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 84 METHOD METHOD ============================================ METHOD Comments from T0514.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0514 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0514.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 84 METHOD METHOD ============================================ MODEL 1 S C 0.82 S C 0.60 L C 0.56 T C 0.55 E C 0.50 T C 0.51 Y C 0.66 G C 0.76 L C 0.67 W E 0.56 S E 0.78 I E 0.83 N E 0.82 C E 0.76 G E 0.61 I C 0.56 Q C 0.77 E C 0.84 G C 0.86 K C 0.73 K C 0.53 V E 0.59 C E 0.66 F E 0.72 M E 0.78 H E 0.77 R E 0.79 Q E 0.77 E E 0.74 V E 0.66 N C 0.58 D C 0.80 Q C 0.89 N C 0.90 R C 0.62 V E 0.79 V E 0.88 V E 0.92 A E 0.93 M E 0.93 S E 0.93 V E 0.92 V E 0.88 L E 0.83 N C 0.55 A C 0.85 D C 0.91 G C 0.87 V C 0.61 V E 0.74 S E 0.87 G E 0.92 N E 0.92 L E 0.92 T E 0.90 V E 0.75 P C 0.56 F C 0.72 G C 0.63 I C 0.49 L E 0.51 V C 0.51 S C 0.79 K C 0.83 P C 0.82 V E 0.56 R E 0.82 L E 0.89 Q E 0.87 V E 0.74 D C 0.72 E C 0.85 G C 0.81 K C 0.77 A C 0.73 V C 0.69 I C 0.60 E C 0.53 T C 0.58 G C 0.50 I E 0.70 R E 0.76 T E 0.76 C E 0.58 V C 0.68 P C 0.81 A C 0.81 G C 0.63 C E 0.61 I E 0.84 V E 0.85 P E 0.83 I E 0.70 V E 0.49 F C 0.76 D C 0.91 K H 0.91 N H 0.94 Y H 0.95 V H 0.96 A H 0.95 A H 0.94 L H 0.91 R H 0.83 A C 0.50 G C 0.90 K C 0.87 H C 0.57 L E 0.77 K E 0.90 L E 0.92 A E 0.91 M E 0.86 T E 0.82 I E 0.64 A C 0.52 A C 0.64 P C 0.74 G C 0.80 E C 0.83 P C 0.86 P C 0.74 L C 0.50 N E 0.70 D E 0.79 L E 0.83 F E 0.85 V E 0.76 Q E 0.64 L C 0.51 N C 0.54 G C 0.57 F H 0.71 S H 0.90 N H 0.93 A H 0.94 L H 0.94 N H 0.90 R H 0.87 L H 0.79 I H 0.76 A H 0.73 L H 0.58 Q C 0.57 K C 0.90 END