PFRMAT SS TARGET T0503 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0503.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0503.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0503.t04.str2.rdb (weight 1.54758) METHOD T0503.t04.alpha.rdb (weight 0.659012) METHOD T0503.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0503.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0503.t2k.str2.rdb (weight 1.54758) METHOD T0503.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0503.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2115 METHOD METHOD ============================================ METHOD Comments from T0503.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2115 METHOD METHOD ============================================ METHOD Comments from T0503.t04.str2.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2115 METHOD METHOD ============================================ METHOD Comments from T0503.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2115 METHOD METHOD ============================================ METHOD Comments from T0503.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 458 METHOD METHOD ============================================ METHOD Comments from T0503.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 458 METHOD METHOD ============================================ METHOD Comments from T0503.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 458 METHOD METHOD ============================================ METHOD Comments from T0503.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0503 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0503.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 458 METHOD METHOD ============================================ MODEL 1 M C 0.72 H H 0.65 T H 0.81 A H 0.85 L H 0.86 I H 0.87 N H 0.82 H H 0.69 I C 0.53 R C 0.59 K C 0.55 F C 0.54 I C 0.69 F C 0.81 L C 0.90 T C 0.93 D H 0.92 E H 0.94 D H 0.94 A H 0.96 G H 0.95 T H 0.94 L H 0.93 S H 0.91 A H 0.79 F C 0.49 F C 0.66 Q C 0.54 L E 0.72 K E 0.78 K E 0.83 V E 0.55 R C 0.80 K C 0.91 K C 0.92 E C 0.51 T E 0.83 L E 0.88 L E 0.83 K E 0.61 T C 0.76 G C 0.88 E C 0.71 I C 0.55 C C 0.59 R C 0.60 I E 0.68 N E 0.87 Y E 0.91 F E 0.93 V E 0.90 V E 0.84 K E 0.59 G C 0.52 C E 0.80 L E 0.90 R E 0.91 L E 0.92 F E 0.91 F E 0.89 I E 0.86 D C 0.62 E C 0.87 K C 0.94 G C 0.91 I C 0.67 E E 0.88 Q E 0.88 T E 0.91 T E 0.88 Q E 0.88 F E 0.87 A E 0.78 I C 0.59 E C 0.85 N C 0.89 W C 0.65 W E 0.54 L E 0.57 S E 0.42 D H 0.49 Y H 0.66 M H 0.73 A H 0.71 F H 0.68 Q H 0.57 K C 0.64 Q C 0.84 Q C 0.84 P C 0.77 A C 0.70 D C 0.45 F E 0.50 Y E 0.67 I E 0.78 Q E 0.82 S E 0.78 V E 0.68 E E 0.57 N E 0.48 C E 0.69 E E 0.87 L E 0.91 L E 0.90 S E 0.89 I E 0.70 T C 0.63 Y H 0.81 T H 0.91 E H 0.93 Q H 0.95 E H 0.95 N H 0.95 L H 0.94 F H 0.92 E H 0.78 R H 0.62 I C 0.75 P H 0.81 A H 0.88 L H 0.93 E H 0.95 R H 0.95 Y H 0.96 F H 0.96 R H 0.96 L H 0.96 V H 0.96 Y H 0.95 Q H 0.95 K H 0.95 S H 0.94 F H 0.95 A H 0.94 A H 0.94 A H 0.94 Q H 0.95 L H 0.94 R H 0.94 S H 0.94 K H 0.94 F H 0.90 Q H 0.80 H H 0.62 M C 0.62 Y C 0.83 S C 0.88 K H 0.93 E H 0.95 E H 0.95 Q H 0.96 Y H 0.96 H H 0.96 N H 0.96 F H 0.95 S H 0.94 S H 0.86 R H 0.72 F C 0.76 P C 0.68 E C 0.59 F H 0.46 I C 0.47 Q C 0.47 R C 0.53 V C 0.73 P C 0.79 Q H 0.90 Y H 0.92 L H 0.92 L H 0.93 A H 0.93 S H 0.90 Y H 0.85 L C 0.49 G C 0.87 F C 0.89 T C 0.92 P H 0.90 E H 0.93 Y H 0.94 L H 0.96 S H 0.96 E H 0.96 I H 0.96 R H 0.95 K H 0.91 K H 0.85 Y H 0.72 I H 0.53 S C 0.88 END