PFRMAT SS TARGET T0492 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0492.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0492.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0492.t04.str2.rdb (weight 1.54758) METHOD T0492.t04.alpha.rdb (weight 0.659012) METHOD T0492.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0492.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0492.t2k.str2.rdb (weight 1.54758) METHOD T0492.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0492.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 61.0306 METHOD METHOD ============================================ METHOD Comments from T0492.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 61.0306 METHOD METHOD ============================================ METHOD Comments from T0492.t04.str2.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 61.0306 METHOD METHOD ============================================ METHOD Comments from T0492.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 61.0306 METHOD METHOD ============================================ METHOD Comments from T0492.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 347 METHOD METHOD ============================================ METHOD Comments from T0492.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 347 METHOD METHOD ============================================ METHOD Comments from T0492.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 347 METHOD METHOD ============================================ METHOD Comments from T0492.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0492 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0492.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 347 METHOD METHOD ============================================ MODEL 1 M C 0.90 F C 0.78 S C 0.73 L H 0.67 R H 0.69 D H 0.62 A C 0.70 K C 0.89 C C 0.87 G C 0.92 Q C 0.70 T E 0.81 V E 0.89 K E 0.91 V E 0.91 V E 0.86 K E 0.86 L E 0.73 H C 0.60 G C 0.86 T C 0.83 G H 0.57 A H 0.86 L H 0.93 K H 0.95 R H 0.95 R H 0.95 I H 0.95 M H 0.93 D H 0.88 M C 0.48 G C 0.89 I C 0.82 T C 0.85 R C 0.89 G C 0.91 C C 0.59 E E 0.86 I E 0.91 Y E 0.92 I E 0.91 R E 0.90 K E 0.89 V E 0.76 A C 0.52 P C 0.76 L C 0.88 G C 0.90 D C 0.85 P C 0.54 I E 0.87 Q E 0.92 I E 0.93 N E 0.93 V E 0.87 R C 0.70 G C 0.84 Y E 0.70 E E 0.88 L E 0.90 S E 0.89 L E 0.75 R C 0.52 K H 0.66 S H 0.71 A H 0.73 A H 0.66 E H 0.52 M C 0.42 I C 0.43 E E 0.61 V C 0.56 E C 0.91 END