a2m2html output for tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0487
- gi|30694320|ref|NP_849784.1|_567:1004 AGO1 (ARGONAUTE 1) [Arabidopsis thaliana]
- gi|15221177|ref|NP_175274.1|_565:1002 AGO1 (ARGONAUTE 1) [Arabidopsis thaliana]
- gi|11386626|sp|O04379|AGO1_ARATH Protein argonaute [Taxonomy]
- gi|5733867|gb|AAD49755.1|AC007932_3 Identical to Argonaute protein from Arabidopsis thaliana gb|U91995. EST gb|AA720232 comes from this gene [Taxonomy]
- gi|2149640|gb|AAC18440.1| Argonaute protein [Arabidopsis thaliana]
- gi|24030354|gb|AAN41341.1| putative leaf development protein Argonaute [Arabidopsis thaliana]
- gi|28209520|gb|AAO37538.1|_588:1022 putative argonaute protein [Oryza sativa (japonica cultivar-group)]
- gi|108711587|gb|ABF99382.1| Argonaute-like protein At2g27880, putative, expressed [Oryza sativa (japonica cultivar-group)]
- gi|157279696|dbj|BAF80153.1| ARGONAUTE family protein [Oryza sativa Japonica Group]
- gi|157357023|emb|CAO63250.1|_596:1034 unnamed protein product [Vitis vinifera]
- gi|84688906|gb|ABC61502.1|_567:1004 AGO1-1 [Nicotiana benthamiana]
- gi|169788718|dbj|BAG12806.1|_627:1062 argonaute1 [Daucus carota]
- gi|166706858|ref|NP_001098067.2|_521:926 piwi protein [Bombyx mori]
- gi|166245168|dbj|BAF73717.2| argonaute 3 [Bombyx mori]
- gi|167860160|ref|NP_001108114.1|_521:926 AGO3 protein [Bombyx mori]
- gi|164605505|dbj|BAF98575.1| AGO3 [Bombyx mori]
- gi|125546068|gb|EAY92207.1|_566:1019 hypothetical protein OsI_013440 [Oryza sativa (indica cultivar-group)]
- gi|8778710|gb|AAF79718.1|AC020889_26_625:1077 T1N15.2 [Arabidopsis thaliana]
- gi|115455965|ref|NP_001051583.1|_566:1023 Os03g0800200 [Oryza sativa (japonica cultivar-group)]
- gi|113550054|dbj|BAF13497.1| Os03g0800200 [Oryza sativa (japonica cultivar-group)]
- gi|125588271|gb|EAZ28935.1|_531:988 hypothetical protein OsJ_012418 [Oryza sativa (japonica cultivar-group)]
- gi|157346648|emb|CAO16717.1|_399:840 unnamed protein product [Vitis vinifera]
- gi|119351181|gb|ABL63483.1|_601:1022 argonaute 2 [Pisum sativum]
- gi|38344266|emb|CAE02070.2|_618:1055 OSJNBa0005N02.3 [Oryza sativa (japonica cultivar-group)]
- gi|156363594|ref|XP_001626127.1|_343:747 predicted protein [Nematostella vectensis]
- gi|156212992|gb|EDO34027.1| predicted protein [Nematostella vectensis]
- gi|193648127|ref|XP_001949977.1|_506:914 PREDICTED: similar to PIWI [Acyrthosiphon pisum]
- gi|193647900|ref|XP_001945669.1|_575:984 PREDICTED: similar to aubergine protein [Acyrthosiphon pisum]
- gi|126842396|gb|ABO27430.1|_471:867 Argonaute3 [Drosophila melanogaster]
- gi|193660928|ref|XP_001949497.1|_446:850 PREDICTED: similar to aubergine protein [Acyrthosiphon pisum]
- gi|156545187|ref|XP_001603582.1|_553:958 PREDICTED: similar to PIWI [Nasonia vitripennis]
- gi|126002279|ref|XP_001352313.1|_410:814 GA19370-PA [Drosophila pseudoobscura]
- gi|54640595|gb|EAL29401.1| GA19370-PA [Drosophila pseudoobscura]
- gi|190616925|gb|EDV32449.1|_460:868 GF14047 [Drosophila ananassae]
- gi|30683679|ref|NP_850110.1|_534:964 argonaute protein, putative / AGO, putative [Arabidopsis thaliana]
- gi|11386645|sp|Q9SJK3|AGOL_ARATH_534:964 Argonaute-like protein At2g27880 [Taxonomy]
- gi|4510428|gb|AAD21514.1| Argonaute (AGO1)-like protein [Arabidopsis thaliana]
- gi|193598905|ref|XP_001942742.1|_555:956 PREDICTED: similar to aubergine protein [Acyrthosiphon pisum]
- gi|190661755|gb|EDV58947.1|_446:843 GG10337 [Drosophila erecta]
- gi|108711472|gb|ABF99267.1|_359:774 Piwi domain containing protein, expressed [Oryza sativa (japonica cultivar-group)]
- gi|125588191|gb|EAZ28855.1| hypothetical protein OsJ_012338 [Oryza sativa (japonica cultivar-group)]
- gi|158299484|ref|XP_319604.4|_517:930 AGAP008862-PA [Anopheles gambiae str. PEST]
- gi|157013540|gb|EAA14901.5| AGAP008862-PA [Anopheles gambiae str. PEST]
- gi|125545984|gb|EAY92123.1|_509:953 hypothetical protein OsI_013356 [Oryza sativa (indica cultivar-group)]
- gi|27819513|gb|AAO24917.1|_364:774 putative argonaute protein [Oryza sativa (japonica cultivar-group)]
- gi|73995329|ref|XP_543433.2|_830:1223 PREDICTED: similar to piwi like homolog 1 [Canis familiaris]
- gi|145509146|ref|XP_001440517.1|_339:756 hypothetical protein GSPATT00009468001 [Paramecium tetraurelia strain d4-2]
- gi|74830558|emb|CAI39070.1| PAZ and PIWI domain protein [Paramecium tetraurelia]
- gi|124407734|emb|CAK73120.1| unnamed protein product [Paramecium tetraurelia]
- gi|145535820|ref|XP_001453643.1|_339:756 hypothetical protein GSPATT00019939001 [Paramecium tetraurelia strain d4-2]
- gi|74830553|emb|CAI39069.1| PAZ and PIWI domain protein [Paramecium tetraurelia]
- gi|124421365|emb|CAK86246.1| unnamed protein product [Paramecium tetraurelia]
- gi|156554763|ref|XP_001605719.1|_375:781 PREDICTED: similar to aubergine [Nasonia vitripennis]
- gi|55978251|ref|YP_145307.1|_308:685 hypothetical protein TTHB068 [Thermus thermophilus HB8]
- gi|55773424|dbj|BAD71864.1| conserved hypothetical protein [Thermus thermophilus HB8]
- gi|46255097|ref|YP_006009.1|_308:685 hypothetical protein TT_P0026 [Thermus thermophilus HB27]
- gi|46197946|gb|AAS82356.1| hypothetical protein TT_P0026 [Thermus thermophilus HB27]
- gi|145533507|ref|XP_001452498.1|_339:755 hypothetical protein GSPATT00002500001 [Paramecium tetraurelia strain d4-2]
- gi|74830583|emb|CAI39075.1| PAZ and PIWI domain protein [Paramecium tetraurelia]
- gi|124420197|emb|CAK85101.1| unnamed protein product [Paramecium tetraurelia]
- gi|110293598|gb|ABG66421.1|_370:774 PAZ PIWI domain protein [Pseudourostyla cristata]
- gi|22298491|ref|NP_681738.1|_352:745 hypothetical protein tll0948 [Thermosynechococcus elongatus BP-1]
- gi|22294671|dbj|BAC08500.1| tll0948 [Thermosynechococcus elongatus BP-1]
- gi|86610170|ref|YP_478932.1|_348:728 Piwi domain protein [Synechococcus sp. JA-2-3B'a(2-13)]
- gi|86558712|gb|ABD03669.1| Piwi domain protein [Synechococcus sp. JA-2-3B'a(2-13)]
- gi|146337912|ref|YP_001202960.1|_57:471 Conserved hypothetical protein; putative Piwi domain [Bradyrhizobium sp. ORS278]
- gi|146190718|emb|CAL74723.1| Conserved hypothetical protein; putative Piwi domain [Bradyrhizobium sp. ORS278]
- gi|154490797|ref|ZP_02030738.1|_192:606 hypothetical protein PARMER_00714 [Parabacteroides merdae ATCC 43184]
- gi|154088545|gb|EDN87589.1| hypothetical protein PARMER_00714 [Parabacteroides merdae ATCC 43184]
- gi|148266051|ref|YP_001232757.1|_60:472 hypothetical protein Gura_4040 [Geobacter uraniireducens Rf4]
- gi|146399551|gb|ABQ28184.1| hypothetical protein Gura_4040 [Geobacter uraniireducens Rf4]
- gi|166706854|ref|NP_001036995.2|_609:1011 argonaute 2 [Bombyx mori]
- gi|166245166|dbj|BAD91160.2| argonaute 2 [Bombyx mori]
- gi|86606806|ref|YP_475569.1|_335:715 Piwi domain protein [Synechococcus sp. JA-3-3Ab]
- gi|86555348|gb|ABD00306.1| Piwi domain protein [Synechococcus sp. JA-3-3Ab]
- gi|164686207|ref|ZP_02210237.1|_330:732 hypothetical protein CLOBAR_02645 [Clostridium bartlettii DSM 16795]
- gi|164601809|gb|EDQ95274.1| hypothetical protein CLOBAR_02645 [Clostridium bartlettii DSM 16795]
- gi|81300343|ref|YP_400551.1|_377:723 hypothetical protein Synpcc7942_1534 [Synechococcus elongatus PCC 7942]
- gi|81169224|gb|ABB57564.1| conserved hypothetical protein [Synechococcus elongatus PCC 7942]
- gi|166364682|ref|YP_001656955.1|_355:746 hypothetical protein MAE_19410 [Microcystis aeruginosa NIES-843]
- gi|166087055|dbj|BAG01763.1| hypothetical protein [Microcystis aeruginosa NIES-843]
- gi|56752529|ref|YP_173230.1|_377:723 hypothetical protein syc2520_d [Synechococcus elongatus PCC 6301]
- gi|56687488|dbj|BAD80710.1| hypothetical protein [Synechococcus elongatus PCC 6301]
- gi|167754324|ref|ZP_02426451.1|_195:609 hypothetical protein ALIPUT_02617 [Alistipes putredinis DSM 17216]
- gi|167658949|gb|EDS03079.1| hypothetical protein ALIPUT_02617 [Alistipes putredinis DSM 17216]
- gi|159027320|emb|CAO86862.1|_355:746 unnamed protein product [Microcystis aeruginosa PCC 7806]
- gi|149237134|ref|XP_001524444.1|_9:437 hypothetical protein LELG_04416 [Lodderomyces elongisporus NRRL YB-4239]
- gi|146451979|gb|EDK46235.1| hypothetical protein LELG_04416 [Lodderomyces elongisporus NRRL YB-4239]
- gi|6630673|dbj|BAA88525.1|_376:758 PAP [Paramecium caudatum]
- gi|25005466|dbj|BAC23150.1| aubergine/piwi homologue [Paramecium caudatum]
- gi|158288103|ref|XP_559969.3|_437:837 AGAP011537-PA [Anopheles gambiae str. PEST]
- gi|157019313|gb|EAL41436.3| AGAP011537-PA [Anopheles gambiae str. PEST]
- gi|84701997|ref|ZP_01016572.1|_61:475 Piwi domain protein [Parvularcula bermudensis HTCC2503]
- gi|84691243|gb|EAQ17083.1| Piwi domain protein [Parvularcula bermudensis HTCC2503]
- gi|188992493|ref|YP_001904503.1|_62:481 putative regulatory protein [Xanthomonas campestris pv. campestris]
- gi|167734253|emb|CAP52463.1| putative regulatory protein [Xanthomonas campestris pv. campestris]
- gi|119493538|ref|ZP_01624204.1|_365:763 hypothetical protein L8106_18222 [Lyngbya sp. PCC 8106]
- gi|119452655|gb|EAW33836.1| hypothetical protein L8106_18222 [Lyngbya sp. PCC 8106]
- gi|170077638|ref|YP_001734276.1|_244:614 conserved hypothetical protein containing Piwi domain [Synechococcus sp. PCC 7002]
- gi|169885307|gb|ACA99020.1| conserved hypothetical protein containing Piwi domain [Synechococcus sp. PCC 7002]
- gi|56478414|ref|YP_160003.1|_333:727 hypothetical protein containing the PIWI domain [Azoarcus sp. EbN1]
- gi|56314457|emb|CAI09102.1| hypothetical protein containing the PIWI domain [Azoarcus sp. EbN1]
- gi|154244391|ref|YP_001415349.1|_140:479 hypothetical protein Xaut_0434 [Xanthobacter autotrophicus Py2]
- gi|154158476|gb|ABS65692.1| conserved hypothetical protein [Xanthobacter autotrophicus Py2]
- gi|182676905|ref|YP_001831052.1|_174:483 conserved hypothetical protein [Beijerinckia indica subsp. indica ATCC 9039]
- gi|182636535|gb|ACB97308.1| conserved hypothetical protein [Beijerinckia indica subsp. indica ATCC 9039]
- gi|68480922|ref|XP_715614.1|_271:628 argonaute-like protein fragment [Candida albicans SC5314]
- gi|68481033|ref|XP_715558.1| argonaute-like protein fragment [Candida albicans SC5314]
- gi|46437185|gb|EAK96536.1| argonaute-like protein fragment [Candida albicans SC5314]
- gi|46437245|gb|EAK96595.1| argonaute-like protein fragment [Candida albicans SC5314]
- gi|62738878|pdb|1Z25|A_475:771 Chain A, Structure Of P.Furiosus Argonaute With Bound Mn2+ [Taxonomy]
- gi|62738879|pdb|1Z26|A Chain A, Structure Of Pyrococcus Furiosus Argonaute With Bound Tungstate [Taxonomy]
- gi|18976909|ref|NP_578266.1|_474:770 hypothetical protein PF0537 [Pyrococcus furiosus DSM 3638]
- gi|18892524|gb|AAL80661.1| hypothetical protein [Pyrococcus furiosus DSM 3638]
- gi|52695955|pdb|1U04|A_475:771 Chain A, Crystal Structure Of Full Length Argonaute From Pyrococcus Furiosus [Taxonomy]
- gi|145607894|ref|XP_365158.2|_544:1001 hypothetical protein MGG_13617 [Magnaporthe grisea 70-15]
- gi|145015372|gb|EDJ99908.1| hypothetical protein MGG_13617 [Magnaporthe grisea 70-15]
- gi|15669511|ref|NP_248321.1|_384:713 hypothetical protein MJ1321 [Methanocaldococcus jannaschii DSM 2661]
- gi|37999509|sp|Q58717|Y1321_METJA Uncharacterized protein MJ1321 [Taxonomy]
- gi|1591961|gb|AAB99334.1| hypothetical protein MJ_1321 [Methanocaldococcus jannaschii DSM 2661]
- gi|84686687|ref|ZP_01014579.1|_183:490 hypothetical protein RB2654_00595 [Rhodobacterales bacterium HTCC2654]
- gi|84665361|gb|EAQ11839.1| hypothetical protein RB2654_00595 [Rhodobacterales bacterium HTCC2654]
- gi|75765647|pdb|1YVU|A_369:705 Chain A, Crystal Structure Of A. Aeolicus Argonaute [Taxonomy]
- gi|83954752|ref|ZP_00963463.1|_149:478 hypothetical protein NAS141_16063 [Sulfitobacter sp. NAS-14.1]
- gi|83841036|gb|EAP80207.1| hypothetical protein NAS141_16063 [Sulfitobacter sp. NAS-14.1]
- gi|15606619|ref|NP_213999.1|_369:704 hypothetical protein aq_1447 [Aquifex aeolicus VF5]
- gi|118137724|pdb|2F8S|A Chain A, Crystal Structure Of Aa-Ago With Externally-Bound Sirna [Taxonomy]
- gi|118137725|pdb|2F8S|B Chain B, Crystal Structure Of Aa-Ago With Externally-Bound Sirna [Taxonomy]
- gi|118137728|pdb|2F8T|A Chain A, Crystal Structure Of Aa-Ago With Externally-Bound Sirna [Taxonomy]
- gi|118137729|pdb|2F8T|B Chain B, Crystal Structure Of Aa-Ago With Externally-Bound Sirna [Taxonomy]
- gi|126031218|pdb|2NUB|A Chain A, Structure Of Aquifex Aeolicus Argonuate [Taxonomy]
- gi|2983852|gb|AAC07406.1| hypothetical protein aq_1447 [Aquifex aeolicus VF5]
- gi|94311099|ref|YP_584309.1|_178:482 hypothetical protein Rmet_2161 [Ralstonia metallidurans CH34]
- gi|93354951|gb|ABF09040.1| conserved hypothetical protein [Ralstonia metallidurans CH34]
- gi|13475183|ref|NP_106747.1|_159:499 hypothetical protein mlr6204 [Mesorhizobium loti MAFF303099]
- gi|14025934|dbj|BAB52533.1| mlr6204 [Mesorhizobium loti MAFF303099]
- gi|170116966|ref|XP_001889672.1|_541:918 argonaute-like protein [Laccaria bicolor S238N-H82]
- gi|164635387|gb|EDQ99695.1| argonaute-like protein [Laccaria bicolor S238N-H82]
- gi|187604166|ref|ZP_02990376.1|_262:591 stem cell self-renewal protein Piwi domain protein [Exiguobacterium sp. AT1b]
- gi|187483715|gb|EDU21709.1| stem cell self-renewal protein Piwi domain protein [Exiguobacterium sp. AT1b]
- gi|20089856|ref|NP_615931.1|_158:466 hypothetical protein MA0979 [Methanosarcina acetivorans C2A]
- gi|19914805|gb|AAM04411.1| conserved hypothetical protein [Methanosarcina acetivorans C2A]
- gi|117922288|ref|YP_871480.1|_159:479 hypothetical protein Shewana3_3856 [Shewanella sp. ANA-3]
- gi|117614620|gb|ABK50074.1| conserved hypothetical protein [Shewanella sp. ANA-3]
- gi|193648085|ref|XP_001945886.1|_424:607 PREDICTED: similar to aubergine protein [Acyrthosiphon pisum]
- gi|21225132|ref|NP_630911.1|_345:666 hypothetical protein SCO6840 [Streptomyces coelicolor A3(2)]
- gi|6900909|emb|CAB71853.1| hypothetical protein SC3D9.08c [Streptomyces coelicolor A3(2)]
- gi|73748042|ref|YP_307281.1|_528:783 hypothetical protein cbdb_A102 [Dehalococcoides sp. CBDB1]
- gi|73659758|emb|CAI82365.1| hypothetical protein [Dehalococcoides sp. CBDB1]
- gi|166706858|ref|NP_001098067.2|_315:452 piwi protein [Bombyx mori]
- gi|166245168|dbj|BAF73717.2| argonaute 3 [Bombyx mori]
- gi|167860160|ref|NP_001108114.1|_315:452 AGO3 protein [Bombyx mori]
- gi|164605505|dbj|BAF98575.1| AGO3 [Bombyx mori]

              10        20           30        40            50        
              |         |            |         |             |        
   1 GLGTPEAVRAQAYRLSIPKLMGRRAVSK...PADALRVGFYRAQETAL...ALL.RLDGAQGWPE
   2 --ILPPPWLKYHESGREGTCLPQVGQWN...MMNKKMINGGTVNNWIC...INF.SRQVQDNLAR
   3 --ILPPPWLKYHESGREGTCLPQVGQWN...MMNKKMINGGTVNNWIC...INF.SRQVQDNLAR
   4 -------PMLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
   5 --ILPAPWLKYHDTGREKDCLPQVGQWN...MMNKKMVNGGTVNNWIC...INF.SRGVQESVAR
   6 ---LPAPWLKYHDTGREKDCLPQVGQWN...MMNKKMVNGGTVNNWIC...VNF.SRNVQDTVAR
   7 --ILPPPRLKYHETGREQDCLPQVGQWN...MMNKKMVGGAAVNYWIC...VNF.ARNVQERAAG
   8 -----LPPETLYFGDNVRVPGKPNAEWN...SEVTKHSVMQAVDIMRW...VLL.FTQRDKQVAM
   9 -----LPPETLYFGDNVRVPGKPNAEWN...SEVTKHSVMQAVDIMRW...VLL.FTQRDKQVAM
  10 --AQEFGIKLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
  11 --ILPPPWLKYHESGREGTCLPQVGQWN...MMNKKMINGGTVNNWIC...INF.SRQVQDNLAR
  12 --AQEFGIKLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
  13 --AQEFGIKLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
  14 --VLPPPMLKYHDSGREAKVDPRVGQWN...MIDKKMVNGGTVQFWTC...LNF.SFRVHQDLPS
  15 -----------------IKISDKLAQVG...QWNKKMVNGGTVNNWFC...VNF.SRSVPDKSAH
  16 ---LPPPRLKYHDSGREKDVLPRVGQWN...MMNKKMVNGGRVNNWAC...INF.SRNVQDSAAR
  17 -----QFPPEKIIYGNTTGSAGDQADWG...RDATREKVISAVNLNNW...MVF.FTQRDSGKAN
  18 -----YKRETILLGSNIRKQVGVNMDWG...MDVAKNAMFVAVNMLNW...AIV.YNPRDETTAK
  19 ------LPPEPIQSRTNGYNGGEEADWT...KNLRSLPMFTSAIMKHW...VIL.APRDCCREVD
  20 ---------EQIYFSKISVSAGRSAEFS...KHAVTNEMLKVVHLSKW...III.HLRNYRQAAT
  21 -----ILPPEPIQSRTNGYNGGEEADWT...KNLRSLPMFTSAIVKHW...VIL.VPREYSQEVD
  22 ------LDPEELVFGNDYKTKSPNADWG...KVATNSKVLRTPNMPDW...AVL.CTQKNQRNCN
  23 --------APQKIVFNQSKCSSGESADWtrcFRDQRLLTTPSEGIDRW...AVI.TPERNSFDLK
  24 ----GRIISPQKIVFSDQKVSAGDTGDWtryFRDQRMLTTPSDGIDRW...AVI.APERNSYDLK
  25 --VLPPPMLKYHDSGKEKMVNPRLGQWN...MIDKKMVNGAKVTSWTC...VSF.STRIDRGLPQ
  26 --VLPPPMLKYHDSGKEKMVNPRLGQWN...MIDKKMVNGAKVTSWTC...VSF.STRIDRGLPQ
  27 --------PEPIQSRSKGYNGGEEADWT...KHLRALPMFTSATVKNW...TIL.APKDCCREVE
  28 ------------HHGKVPAGENADWQRH...FRDQRMLTTPSDGLDRW...AVI.APQRNSSELR
  29 --AQEFGIKLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
  30 --GRQLPPENITSGGGVVGSAGPNVDYT...RQVTNNPMLEIVHIRQW...MLL.YTQRDEQHAS
  31 --AQEFGIKLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
  32 -------PMLKYHDSGREKTCAPSVGQW...NMINKKMINGGTVDNWT...CLS.FSRMRPEEVQ
  33 -----------------FDSHPQFADWS...RETRSGPLLNVKSLDHW...LIL.YPTRNYGAAS
  34 --IQSSKIKPGNIMMGNNTAINIETGNL...DRDTQTAMLRGVGLENW...GIL.YSDRDGRQAE
  35 --IQSSKIKPGNIMMGNNTSINIETGNL...DRDTQTAMLRGVGLENW...GIL.YSDRDSRQAE
  36 ----GRVLPMETIYFGSKKVLLKQADWT...VDVQDAVPVSCRPLKDW...VAI.VPNKSSESAK
  37 ------AVRAQAYRLSIPKLMGRRAVSK...PADALRVGFYRAQETAL...ALL.RLDGAQGWPE
  38 ------AVRAQAYRLSIPKLMGRRAVSK...PADALRVGFYRAQETAL...ALL.RLDGAQGWPE
  39 --IQSSKVKPGNIIMGNNTQINIETGNL...DRDTQTAMLRGVGLENW...AIL.YGDRDSRQAE
  40 ---GNMIMGAKPNGERNIFDIDQCSREI...DRKIQDKMFDQPALKMW...GIF.HGDRDAGIAK
  41 ---QPEIMKVNGFVMPRAKLLARNNKEV...NQTARIKSFGCAKIGETkfgCLN.LFDNKPEYPE
  42 --ADPLKAEGYIMPSPRLLGFGHRQVQN...PARVRYQGCARVGETKF...GLLnLDDNKREYPT
  43 ----ARQGNRLYGFMKELASQYRPTERK...DYLPPWPGFRKVFNVEM...RGA.VKDCHIELDD
  44 ---IGSICPTSYSLKFSEFLKRLNSTVS...ADKLSDYVHHYTGFSNI...YNC.RLDIPEIHSE
  45 -------SRHLYGFMKELNSVVKATERA...EYLPEWPGFHSVFGLHM...RGA.GAGCHIELDT
  46 ------KILEAPTLEVGPRQFTVPKKGV...WQANCLLKPEALNSWGF...IAI.ELDPRGCNYE
  47 -----LKTQGYILPKPKLLGSGRRPVEN...PARVRYRGCAKVGETKF...ACLnLYDDKREYPS
  48 ------KRPALKFGKNESNFSAMYGLNK...SGSYEQKNIEIDYFIDP...KIL.NNKRDYQIVY
  49 ----------------------------...---------------SF...GYLnLYNNQLQYPL
  50 ----GEKREIIKGLSKGGVYKRHREYVD...PARKIRLAILKPANLKV...GDF.REQLEKRLKL
  51 ----------------------------...---------------SF...GYLnLYNNQLQYPL
  52 ---LGVICPNAHTNSLKSFLQRLNTTIQ...ANDNSDYIQPYTGFHSI...YKT.LLEIPDSDTD
  53 ----GEKIKTLKGLSKGGVYKRHREYLD...PARKIRLAILKPANLKV...GDF.REQLEKRLEL
  54 ------VTGIWKRCNFTCRPRARKVTTL...VCLFWLIVFSKKRGSIL...VRR.ARFSLPELNR
  55 ---------------------MNTNLDR...QTQTQMYSTPQQQLILG...IIM.NEKSGSQVLD
  56 ----EKIPPQRGVWRAEGKNFIVPSTEL...SKRPLRWRILNLDSYTN...EAT.VKKFGEMLQS
  57 -IGQQGMIGKMRGLVSELEATLRPRDAA...AYRPDYQGMSKTFGVRP...VGA.GSASEIILPD
  58 --GPESAFKTRGVLMASLKQQHAASDRS...GYAPDFPGFASVFGVDL...ASS.DKANHIRWPD
  59 ----------LKGLSQGGVYRRHQDYEN...YSTPIRISLLNLCNSKV...GKF.VSQVEERLKQ
  60 ----------------------------...---------------GC...INL.LDKNQDGWSK
  61 -----RDLKPEFRLLFRGAAVADSERAV...LRHGAYQGMTRKLVVPL...VVG.GTALEQAVAV
  62 ----------------------------...-----------------...---.----------
  63 ----------------------------...-----------------...---.----------
  64 ----------------------------...-----------------...---.----------
  65 ----------------------------...-----------------...---.----------
  66 ----------------------------...-----------------...---.----------
  67 ----------------------------...-----------------...---.----------
  68 --------GWNMRNCKFNEVVGGGTSRP...WGCLTLDGRYPANSQHL...VAQ.LEAFRLHLSK
  69 ----------------------------...-----------------...---.----------
  70 ----------------------------...-----------------...---.----------
  71 ----------------------------...-----------------...---.--------KE
  72 ----------------------------...-----------------...---.----------
  73 ----------------------------...-----------------...---.--------KE
  74 ----------------------------...-----------------...---.----------
  75 ----------------------------...-----------------...---.----------
  76 ----------------------------...-----------------...---.-SGPKDPRLM
  77 ----------------------------...-----------------...---.---HQKLQVL
  78 ----------------------------...-----------------...---.----------
  79 ----------------------------...-----------------...---.----------
  80 ----------------------------...-----------------...---.----------
  81 ----------------------------...-----------------...---.----------
  82 ----------------------------...-----------------...---.----------
  83 ----------------------------...-----------------...---.----------
  84 ----------------------------...-----------------...---.----------


      60          70                   80              90              
      |           |                    |               |              
   1 FL.RRALLR.AFGASGASLR..L.H.....T...L...H...AHPSQGLAFRE.....ALRKAK.
   2 TF.CQELAQ.MCYVSGMAFN..P.E.....P...V...L...PPVSARPEQVE.....KVLKTRy
   3 TF.CQELAQ.MCYVSGMAFN..P.E.....P...V...L...PPVSARPEQVE.....KVLKTRy
   4 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSTNPNNIEn12seLLAREG.
   5 GF.CQELAQ.MCYISGMAFN..P.E.....P...V...L...PPITARPDQVE.....RVLKARf
   6 GF.CSELAQ.MCMISGMNFN..P.N.....P...V...L...PPVSARPDQVE.....RVLKTRf
   7 GF.CYELAN.MCNVSGMQFK..P.E.....P...V...L...PAYNARSDQVE.....RMLKSRi
   8 DF.LSTLKR.NCRPMGIMVS..D.A.....E...L...V...PLANDRTDTYVl....ALKKCI.
   9 DF.LSTLKR.NCRPMGIMVS..D.A.....E...L...V...PLANDRTDTYVl....ALKKCI.
  10 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSTNPNNIEn12seLLAREG.
  11 TF.CQELAQ.MCYVSGMAFN..P.E.....P...V...L...PPVSARPEQVE.....KVLKTRy
  12 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSTNPNNIEn12seLLAREG.
  13 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSTNPNNIEn12seLLAREG.
  14 GF.CRELVN.MCVSKGMVFN..P.N.....P...L...L...PIQSAHPNQIE.....KVLVDVh
  15 AF.CCELAN.MCHISGMAFN..P.E.....P...V...L...PPLSARPDQVE.....KVLRRRy
  16 GF.CHELAI.MCQISGMDFA..L.E.....P...V...L...PPLTARPEHVEr11am------n
  17 DF.VQTMNK.CAPAMGIQVN..Q.P.....K...M...N...QLRDDRTETYL.....RSIRENl
  18 SF.CKQLVS.CGRPLGMEIN..P.P.....K...P...I...KVQGTNPEVFV.....STINSTl
  19 LF.AQTLVK.TAQGMNFTLP..K.P.....S...I...V...PMNDGKANTFLsn...LEQVIN.
  20 SL.LDNMKQ.ACESLGMNIS..N.P.....T...M...I...SLDHDRIDAYIq....ALRRNI.
  21 PF.VQSLAK.AASGMNFTLP..K.P.....T...V...V...SMEDGRANSVL.....THLEHIt
  22 DF.VETLKG.VCQKVNIRIG..D.P.....R...L...I...FLKDDSTETYVs....ELRKVV.
  23 TV.LDSLFR.AASGMGLKIR..S.P.....H...V...I...KIQDDRTGSYVr....AMDSCA.
  24 NL.MENMFR.AASGMGLRIK..T.P.....H...E...L...KIYDDRTATYIr....AMDDCA.
  25 EF.CKQLIG.MCVSKGMEFK..P.Q.....P...A...I...PFISCPPEHIEe....-ALLDIh
  26 EF.CKQLIG.MCVSKGMEFK..P.Q.....P...A...I...PFISCPPEHIEe....-ALLDIh
  27 AF.AQSLSK.AAQGMTFVLP..R.P.....V...I...F...PMVDGRSNTFLnd...LEKVIN.
  28 AL.LDCLYR.ASSGMGLRIR..S.P.....Q...E...F...IIYDDRTATYVr....AMDDCA.
  29 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSSNPNNIEn12seLLAREG.
  30 VF.RDCVKR.TCKLLGLEVA..Q.P.....Q...V...E...VLPQDATNLYVq....ALRTRI.
  31 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSSNPNNIEn12seLLAREG.
  32 RF.CGDLIQ.MCNATGMSFN..P.R.....P...V...V...DVRSSNPNNIEn12seLLAREG.
  33 SL.VQSLRK.VTPTMGIAMR..E.A.....K...M...L...EVSDTVQSYTT.....VLENHV.
  34 DF.MSCLRE.SIEYCKFQCK..A.P.....R...T...F...VLHSNRIEDWI.....KQIDQIv
  35 DF.MSCLRE.SIEYCKFQCK..A.P.....R...T...F...VLHSNRIEDWI.....KQIDQIv
  36 AF.IELIIT.VASKMKFAIS..R.P.....R...L...V...MIDNDKSETVA.....QTITAIt
  37 FL.RRALLR.AFGASGASLR..L.H.....T...L...H...AHPSQGLAFRE.....ALRKAK.
  38 FL.RRALLR.AFGASGASLR..L.H.....T...L...H...AHPSQGLAFRE.....ALRKAK.
  39 DF.MSCLRE.SIEYCKFQCK..A.P.....R...T...F...TIHSSRIEDWI.....KQIDFIv
  40 QF.SSTMEQ.CLQQFGYESA..A.P.....A...I...F...QVRSAMQADNWkk...ELKSRL.
  41 EV.HKCLLA.IARSSGVQIK..I.D.....S...Y...FtgsDYPKDDLAQQR.....FWQQWA.
  42 EV.RKCLLE.VAKKSGARVE..I.D.....F...Y...AtrqDLPEGDLAQQR.....FWQSWA.
  43 RL.EGEMKDsAAPHVLLAER..L.L.....R...A...I...QSLEARRDAFD.....IVFIYI.
  44 KW.VSINDN.PKSAINLAKT..I.C.....T...E...G...QKLSEQFPGIV.....LLIFVP.
  45 EFeAEFHAS.STPHIVLADR..L.I.....R...K...I...QALEAHRDKFD.....VLFIYI.
  46 DI.VSKLMN.TGRQMGMNVT..Q.P.....K...M...A...CFNIRINDLHK.....SMLHAL.
  47 EV.LNCLLE.VAQKSGAEIE..V.D.....F...Y...AtqqDLPKGDLARKR.....FWQTWA.
  48 SF.LNDIIS.KSKDLGVEIN..T.Dks7ltP...I...N...IKNENVFELNI.....IQIIEN.
  49 EV.HKCLLE.IANKNNLQLS..L.D.....QrrvL...S...DYPQDDLDQQM.....FWQTWS.
  50 YK.FETILP.PENQINFSVE..G.L.....G...F...E...KRARLEEAVDR.....LIGVEI.
  51 EV.HKCLLE.IANKNNLQLS..L.D.....QrrvL...S...DYPQDDLDQQM.....FWQTWS.
  52 KW.IKTEDT.PRDTISLAQS..I.C.....H...K...A...GSLAEKYPGIV.....VVIYIP.
  53 YK.FETILP.AENQINFSVE..G.V.....G...F...E...KRARLEEAVDQ.....LIRGEI.
  54 LG.IKNAGS.KYQRYSVDLE..S.P.....A...V...A...DEQSLEKSLVD.....LFSKAK.
  55 VF.MENFLA.ACHEFKFFTF..L.P.....P...K...V...LSINSDTDDELer8lkNQALLN.
  56 QA.MRCNVQ.M-EPFDMAKT..Y.V.....L...V...R...DMRNCLRDIGT.....LLQNIK.
  57 TL.TDDVRR.ARKPYVVLAEa.L.Q.....R...A...I...TQLKATRNDFD.....VVFIGI.
  58 SI.DDLPGS.GTLQHRLVAA..F.E.....A...A...L...SQLSTRHEQFD.....VVLVHL.
  59 YK.FETIRF.EKDSLDRRKE..IkV.....D...N...L...DSAEARVAVEK.....ALDELM.
  60 FI.LQKLQK.LATIHNINID..A.N.....L...VkaaV...DIPEKDFEIDQ.....FWESWV.
  61 RH.FEAVER.VCRQWHSDLP..S.W.....K...T...A...PPAGDAEALNQ.....RLAQRK.
  62 --.------.---------S..A.K.....P...D...V...IVLALPIPLIE.....KLVNAK.
  63 --.------.----------..-.-.....-...-...-...-----------.....------.
  64 --.------.----------..-.-.....-...V...Q...SQTGLESNIIS.....IAKKAKt
  65 --.------.----------..-.-.....-...-...-...-----------.....------.
  66 --.------.----------..-.-.....-...-...-...-----------.....------.
  67 --.------.----------..-.-.....-...-...-...-----------.....------.
  68 AG.INLDQC.KIRSCTVGRS..T.T.....Q...D...F...SVLDETLGMLKpt...KTKDGI.
  69 --.YNKIAN.KTELPKFNYA..N.R.....W...K...Y...FSTDDIRGIIK.....EIKSEF.
  70 --.------.----------..-.-.....-...-...-...-----------.....------.
  71 EF.LKELIN.FLKNKGIKLK..I.K.....G...K...Sl..ILAQTREEAKE.....KLIPVI.
  72 --.------.----------..-.-.....-...-...-...---SMPIDLIE.....KVVMAR.
  73 EF.LKELIN.FLKNKGIKLK..I.K.....G...K...Sl..ILAQTREEAKE.....KLIPVI.
  74 --.------.----------..-.-.....-...-...-...-----------.....------.
  75 --.------.----------..-.-.....-...-...-...-EGSSRPDVAIia7el------i
  76 GL.VQGFAT.KLKNSGVNIPtgL.P.....R...L...I...PPPTLPPPYSDpsrtqGLRNIKl
  77 EF.INKLKT.TSERFGVTLN..V.S.....H...K...P...KGLSQKLPSDLlq7ilYQLKNIp
  78 --.------.----------..-.-.....-...-...-...-----------.....------.
  79 --.------.----------..-.-.....-...K...E...KGKDEDPENYDgd8ks------.
  80 --.------.----------..-.-.....-...-...-...-----------.....------.
  81 --.------.----------..-.-.....-...-...-...-----------.....------.
  82 --.------.----------..-.-.....-...-...-...-----------.....------.
  83 --.------.----------..-.-.....-...-...-...-----------.....------.
  84 --.------.----------..-.-.....-...-...-...-----------.....------.


         100          110                 120           130       140  
          |            |                   |             |         |  
   1 ....EE..G.VQAVLVLTPP.....MAWE.....DRNRLKALL.L...REGLPSQILNVPLREEE
   2 10sqGK..E.IDLLIVILPD.....NNGSl....YGDLKRICE.T...ELGIVSQCCLTKHVFKM
   3 10sqGK..E.IDLLIVILPD.....NNGSl....YGDLKRICE.T...ELGIVSQCCLTKHVFKM
   4 ....KG..G.LQLLIVILPE.....VSGS.....YGKIKRVCE.T...DLGIVSQCCLPRHASRP
   5 11pqGK..E.LDLLIVILPD.....NNGSl....YGDLKRICE.T...DLGLVSQCCLHKHVYRM
   6 11pnGR..E.LDLLIVILPD.....NNGSl....YGDLKRICE.T...ELGIVSQCCLTKHVFKM
   7 k8taKQ..G.IDLLIAILPD.....NNGSl....YGDLKRICE.T...DLGVISQCCLAKHVFRM
   8 ....TS..S.VQLVVAICST.....KRDDr....YAAIKKVCC.A...DNPVPSQVINARTLMNT
   9 ....TS..S.VQLVVAICST.....KRDDr....YAAIKKVCC.A...DNPVPSQVINARTLMNT
  10 ....KG..G.LQLLIVILPE.....VSGS.....YGKIKRVCE.T...DLGIVSQCCLPRHASRP
  11 10sqGK..E.IDLLIVILPD.....NNGSl....YGDLKRICE.T...ELGIVSQCCLTKHVFKM
  12 ....KG..G.LQLLIVILPE.....VSGS.....YGKIKRVCE.T...DLGIVSQCCLPRHASRP
  13 ....KG..G.LQLLIVILPE.....VSGS.....YGKIKRVCE.T...DLGIVSQCCLPRHASRP
  14 14qnGK..Q.LQLLIIILPD.....VTGS.....YGKIKRICE.T...ELGIVSQCCQPSQASKL
  15 h9lqGK..E.PDLLIVILPD.....NNGSl....YGDLKRICE.T...DLGVVSQCCLTKHVFKM
  16 m6pqGR..E.LDLLIVILPD.....NNGSl....YGDLKRICE.T...DLGLVSQCCLTKHVFKM
  17 ....HP..Q.VQVVVVIFPT.....SRDDr....YAAVKKLCC.V...ESPVPSQVIISKTISNP
  18 kn..NS..D.IQIVVIIFPN.....QREDr....YNAVKRICC.S...EIGIPSQVIVSRTLSKP
  19 ....VS..N.PAFILCVIPS.....ARGDi....YSLIKRKLC.I...DRAVPSQVVLLKNVQKN
  20 ....TM..N.TQMVVCICHN.....RRDDr....YAAIKKICC.S...EIPIPSQVINAKTLQND
  21 n...EH..N.PALILCIIQS.....PRGDi....YSLIKRKLC.I...DRAVPSQVVLLKNVKKR
  22 ....KN..R.LNMVVIIFPA.....LRQDk....YSAVKKICC.V...ETPVPSQVIISRTIAKP
  23 ....DM..D.PKLILCLVPN.....NNVEr....YSSIKKRGC.V...DRAVPTQVVTIKTSKNR
  24 ....RM..D.PKLILCLVPN.....NNADr....YSAIKKRGY.V...DRAVPTQVVTIKTAKNR
  25 kr..AP..G.LQLLIVILPD.....VTGS.....YGKIKRICE.T...ELGIVSQCCQPRQVNKL
  26 kr..AP..G.LQLLIVILPD.....VTGS.....YGKIKRICE.T...ELGIVSQCCQPRQVNKL
  27 ....ES..N.PSLILCVIPS.....ARGDi....YSMIKRKLC.I...DRAVPSQVVLLKNVQKN
  28 ....RS..D.PKLILCLVPN.....DNVEr....YSSIKKRGY.V...DRAVPTQVVTIKTTKNR
  29 ....KG..G.LQLLIVILLE.....VSGS.....YGKIKRVCE.N...DLGIVSQCCLPRHASRP
  30 ....RP..G.TQIVVIICPT.....SRDDr....YAAIKRILC.T...EVPIPSQVINARTLANE
  31 ....KG..G.LQLLIVILLE.....VSGSyg7vgWGKLKGYVR.M...TLALYLNVVCQGMPAGR
  32 ....KG..G.LQLLIVILLE.....VSGS.....YGKIKRVCE.N...DLGIVSQCCLPRHASRP
  33 ....SS..K.TQMVLCVLSS.....EKKDl....YDGIKQYLC.V...NCPTPSQCVVARTLDKP
  34 q6qgPQ..K.VTLLLLILNG.....PKKNapl..YTDIKRYLI.N...DCPIASQVILSSTLNQP
  35 q6qgPQ..K.VTLLLLILNG.....PKKSapl..YTDIKRYLI.N...DCPIASQVILSSTLNQP
  36 dk..SV..P.QLIFCVVFNN.....NLLR.....YQAIKKKLC.L...DRPIPSQVVMSRTLVQK
  37 ....EE..G.VQAVLVLTPP.....MAWE.....DRNRLKALL.L...REGLPSQILNVPLREEE
  38 ....EE..G.VQAVLVLTPP.....MAWE.....DRNRLKALL.L...REGLPSQILNVPLREEE
  39 q6qgPQ..K.VTLLLLILNG.....PKKNapl..YTDLKRYLI.N...DCPIASQVILSSTLNQP
  40 ....NQ..N.VQAVVLLLPG.....QKGKcnl..YDEVKKYLL.T...DVPVPSQAVLTGTIQKG
  41 ....AQ..G.IKTVLVVMPW.....SPHE.....EKTRLRIQA.L...KAGIATQFMIP-TPQDN
  42 ....DK..G.IKTVLVVMPL.....SPNE.....HKQKIRLQA.L...RAGIATQFMIPGA---D
  43 ....PL..S.WAAGFSGAEG.....DDFD.....LHDHLKAAT.A...ARRIPIQLVREDRALAY
  44 ....NS..W.SNYRQFNYHG.....ETFD.....LHNYIKAFA.A...QHRFTTQFIEEKTLYNK
  45 ....PQ..R.WTPGYTGSHG.....EDFD.....LHDHLKAAT.A...ARRLPVQFVREDKALAY
  46 ....EK..Q.VNFLVVVVSG.....RGRDy....YHKLKQIAE.L...KVGILTHVFKEDTATRR
  47 ....EQ..G.IKTVLVVMPW.....SPNE.....RKQRIRMEA.L...EAGIATQFMIPGA---D
  48 ....YN..N.PVLVILEKEN.....IDKY.....YETLKKIFG.G...RNNIPTQFVDLDTIKKC
  49 ....SQ..G.IKTVLVVMPW.....DSHH.....DKQKIRIQA.I...QAGIATQFMVP-LPKAD
  50 ....PV..D.IALVFLPQED.....RNADnt6gsLYSWIKRKF.L...GRGVITQMIYEKTLNDK
  51 ....SQ..G.IKTVLVVMPW.....DSHH.....DKQKIRIQA.I...QAGIATQFMVP-LPKAD
  52 ....TS..W.SLHKQFKHDG.....ESFD.....LHNYIKAYA.A...QHSFTTQIIEEKTLKDP
  53 ....PV..D.IALVFLPQED.....RNADnt6gsLYSWIKKKF.L...ERRVMTQMIYEKTLNDK
  54 ....NK..DkCDFLLVVLPS.....KDARf....YRAVKRAGD.L...KVGINNSCVIVDTFTKR
  55 ....KV..K.VGFLIFLLPG.....QKKKakl..YKTAKKISM.Q...SFGCPSQVIIEKTLQKN
  56 ....RE..E.PAVTIVVLPS.....RGDA.....YAKVKQKAE.LaseRIGLLTQCVKGMTVAKK
  57 ....DA..A.WEPAFVERDE.....EDFD.....LHDYLKAVG.A...SMGVSVQLIRSDKALDY
  58 ....PE..A.W---LPYTSG.....DGFD.....AHDVLKALG.A...KHGIPTQVVNDRTFSFS
  59 ....VI..P.TNIVLTFLPEsd8dtEDGS.....FYSFVSSRL.L...RRGISSQVIYEDTLKNP
  60 ....EQ..D.IKTILVISEW.....LDNK.....YKTKLTRDA.L...EHGITLQFMLPLKENVR
  61 ....PE..N.ALLLIGLGRG.....AD--.....-KRKIRNVA.Y...RYGLATQFMRLDHPPRT
  62 ....SE..G.EDSDDDVDGG.....DMLN.....FRDLLKAKT.L...HLPVPTQIVWPDTWDDA
  63 ....--..-.------SGGS.....DAPN.....FRGLLKAKA.M...SLNFPIQILWEDVIDEK
  64 ....ED..Q.CNFLLFILPR.....QDTPl....YSAIKRACD.L...KVGILNSCSILNTFTKK
  65 ....--..-.-LAFIAARNK.....LSSE.....KFEEIKRRL.F...NLNVISQVVNEDTLKNK
  66 ....--..-.-LAFIAARNK.....LSSE.....KFEEIKRRL.F...NLNVISQVVNEDTLKNK
  67 ....--..-.-LAFIAARNK.....LSSE.....KFEEIKRRL.F...NLNVISQVVNEDTLKNK
  68 ....RR..P.FDFVLIILPD.....KDVS.....RYNMIKYLGdV...CYGVPTVCVASRTFFPA
  69 ....ND..E.ICFALIIGKEky...KDND.....YYEILKKQL.F...DLKIISQNILWENWRKD
  70 ....--..-.---------E.....TSPN.....FRGLLKARA.M...DLRFSIQIVWEDVINPD
  71 ....NKikD.VDLVIVFLEEyp7pyKSFL.....LYDFVKREL.L...KKXIPSQVILNRTLKNE
  72 ....SE..N.GE------PD.....DDGGpdvlnFRDMMKAKM.M...ELGVATQIVWPDVFDPD
  73 ....NKikD.VDLVIVFLEEyp7pyKSFL.....LYDFVKREL.L...KKMIPSQVILNRTLKNE
  74 ....--..-.---------G.....STFD.....LRNMLKAKV.M...RMNQPIQLVLPQTYDET
  75 e7naKV..D.SDATLEEEDS.....SGSDapn..FRGMLKAKA.M...HFRFPIQIVWEDVLDER
  76 t9ktQK..K.PSFVLVLLEN.....RDNYi....YPGIKRICD.V...ELGIHTVHMQLGKALTD
  77 qh..FE..G.VVVVIAEEAS.....LQHS.....YQAIKRQFG.G...KQDVVTQCVELHDRVLN
  78 ....--..-.----ICECSE.....TDKPli8ddFRNRIKLLA.M...QQKIPSQIVRPETLLLD
  79 ....--..-.-------KNS.....LEHN.....FRRLLKAKT.M...HLGKPLQLVLEKSLSID
  80 ....--..-.----------.....----.....---------.-...-----------------
  81 ....SG..D.IDLAIVITSE.....AQAHlt6ssPYLVAKSAF.M...GQGVPVQEVRIETVRQS
  82 ....--..-.----------.....----.....---------.-...-------------GKLN
  83 ....--..-.----------.....----.....---------.-...-----------------
  84 ....--..-.----------.....----.....---------.-...-----------------


                150        160                170       180            
                 |          |                  |         |            
   1 .....RHRWENALLGLLAKA.GLQVVAL....SGA.....YPAELAVGFDAGG.....RESFRFG
   2 s....KQYMANVALKINVKV.GGRNTVL....VDAls9vsDRPTIIFGADVTHphpgeDSSPSIA
   3 s....KQYMANVALKINVKV.GGRNTVL....VDAls9vsDRPTIIFGADVTHphpgeDSSPSIA
   4 n....KQYLENVALKINVKV.GGRNTVL....ERAf10vsEVPTIIFGADVTHpppgeDSASSIA
   5 s....KQYLANVALKINVKV.GGRNTVL....VDAis9vsDRPTIIFGADVTHphpgeDSSPSIA
   6 s....KQYLANVSLKINVKV.GGRNTVL....VDAls9vsDRPTIIFGADVTHphpgeDSSPSIA
   7 s....KQYLANVALKINVKV.GGRNTVL....VDAls9vsDRPTIIFGADVTHphpgeDSSPSIA
   8 nki..RSITQKILLQLNCKL.GGTLWSI....SIP.....FKSAMIVGIDSYHdps..RRNRSVC
   9 nki..RSITQKILLQLNCKL.GGTLWSI....SIP.....FKSAMIVGIDSYHdps..RRNRSVC
  10 n....KQYLENVALKINVKV.GGRNTVL....ERAf10vsEVPTIIFGADVTHp19laNGSSIHY
  11 s....KQYMANVALKINVKV.GGRNTVL....VDAls9vsDRPTIIFGADVTHphpgeDSSPSIA
  12 n....KQYLENVALKINVKV.GGRNTVL....ERAf10vsEVPTIIFGADVTHpppgeDSASSIA
  13 n....KQYLENVALKINVKV.GGRNTVL....ERAf10vsEVPTIIFGADVTHpppgeDSASSIA
  14 n....KQYFENVALKINVKV.GGRNTVLf...-DAiq9vsDLPTIIFGADVTHpqpgeDSSPSIA
  15 n....KQYLANVSLKINVKV.GGRNTVL....VDAls9vsDRPTIIFGADVTHphpgeDSSPSIA
  16 s....KQYLANVALKINVKV.GGRNTVL....VDAlt9vsDRPTIIFGADVTHphpgeDSSPSIA
  17 tkl..RSVVQKIALQINVKL.GGELWAL....DIP.....SRSLMVCGIDVYHdka..RGGRSVG
  18 erl..QSITQKIALQINCKL.GGACWAI....DIP.....LKNTMIVGIDVYHekg..KQMSSVV
  19 d....LSICTKIAIQINCKL.GGAPWLV....TIP.....KKGMMIVGFDVCHdsq..RKNISFG
  20 lki..RSVVQKIVLQMNCKL.GGSLWTV....KIP.....FKNVMICGIDSYHdps..NRGNSVA
  21 d....MSVCTKIAIQINCKL.GGAPWLV....TIP.....KKGMMIVGFDVCHdsq..RKNISFG
  22 ekl..KSVTEKIALQINCKL.GGALWAL....KNP.....FTNAMVCGIDVFHagvgqGSKGSVA
  23 gl...LSIATKIAIQLNCKL.GYTPWMI....ELP.....LSGLMTIGFDIAKsar..DRRKAYG
  24 gl...MSIATKIAIQINCKL.GYTPWMV....EVP.....LSGLMTIGFDIAKstr..DRKKAYG
  25 n....KQYMENVALKINVKT.GGRNTVL....NDAir9itDRPTIIMGADVTHpqpgeDSSPSIA
  26 n....KQYMENVALKINVKT.GGRNTVL....NDAir9itDRPTIIMGADVTHpqpgeDSSPSIA
  27 n....LSVCTKIAIQINCKL.GGAPWLV....TIP.....KKGMMIVGFDVCHdsq..RKNISFG
  28 sl...MSIATKIAIQLNCKL.GYTPWMI....ELP.....LSGLMTIGFDIAKstr..DRKRAYG
  29 n....KQYLENVALKINVKK.SQQSSLV....LMS.....HTP----------pge..DSASSIA
  30 krn..RSVVLKVLLQMNCKL.GGSLWGV....RVP.....IKRTMICGIDTYHeak..QRSNSVA
  31 t....SNICENVALKINVKV.GGRNTVL....ERAf10vsEVPTIIFGADVTHsppgeDSASSIA
  32 n....KQYLENVALKINVKK.SQQSSLV....LMS.....HTP----------pge..DSASSIA
  33 qtl..MTIATKIAQQMNCKM.GGALWKV....ETG.....LQNAMFIGIDCFHdiv..NRRKSIA
  34 kgkv.KTICNKLLVQICAKV.GGTPWGV....SELpft..DQPTMICGMDVYHstg..KAKKSML
  35 kgkv.KTICNKLLVQICAKV.GGTPWGV....SELpft..DQPTMICGMDVYHstg..KAKKSML
  36 tpantRSVATKVAVQLNCKM.GGVPWTT....DIGqi...LPGLMVVGFDVCH.....DKNGDFG
  37 .....RHRWENALLGLLAKA.GLQVVAL....SGA.....YPAELAVGFDAGG.....RESFRFG
  38 .....RHRWENALLGLLAKA.GLQVVAL....SGA.....YPAELAVGFDAGG.....RESFRFG
  39 kgkv.KTICNKLLVQICAKV.GGTPWGI....SDLpft..DQPTMICGMDVYHsta..KGRKSML
  40 knl..RSIVNKILIQINVKI.GGIPWAV....DSLpll..TKPSMICGMDVFHsts..LGKKSVL
  41 .....PYKALNVALGLLCKA.KWQPVYLkpl.DDP.....QAADLIIGFDTST.....NRRLYYG
  42 .....PYKALNVVLGLLCKA.AWQPVLLepl.DHP.....ECSELTIGFDVGT.....NRELYYG
  43 pdr..ASVMWRIGLAIYAKA.GGVPWKL....ADS.....DPEAAYIGLSYALrptesDRPRFVT
  44 mv...CKISWWLSLALFVKA.LRTPWTL....ADL.....DQNTAYAGIGYSIkkqysGKAEVVL
  45 phr..ASVMWRIGLALYAKA.GGVPWKL....AET.....DAETAYIGISYAVrppdsGRSRFVT
  46 mn...PQTARNILLKVNSKL.MGINQAL....ENRsi7lkGGAVMIVGADVTHpspd.QSNIPSI
  47 .....PYKALNVVLGLLCKA.AWQPVLLepl.DDP.....VGPELIIGFDVGT.....NRRLYYG
  48 d10gkESIFLNILLGIYCKS.GIQPWVL....ANG.....LSADCYIGLDVCR.....ENNMSTA
  49 .....KYKALNVTLGLLCKA.GWQPIQLesv.DHP.....EVADLIIGFDTGT.....NRELYYG
  50 sny..KNILNQVVPGILAKL.GNLPYVLa...EPL.....EIADYFIGLDVGRmp6nlPGSLNVC
  51 .....KYKALNVTLGLLCKA.GWQPIQLesv.DHP.....EVADLIIGFDTGT.....NRELYYG
  52 mv...CEICWWLSLALFVKA.MRIPWAL....ASL.....DSDTAYAGIGYSVktngkGKVDIVL
  53 sny..KNILNQVVPGILAKL.GNLPYVLa...ESL.....EIADYFIGLDVGRmp6nlPGSLNVC
  54 kf6fdMTLFAQVGMKVNLKL.GGSNHKL....SDAns9ekKVPVFILGADVTHptgesNEESVSI
  55 t....RSIVNKILIQLNAKV.GGIPWAL....DGFpqqfqAKPTMICGVDIFSk....HGKKNQL
  56 gtd..MSTLNNIMLKINAKT.NGTNHCIsqva---vpplgRGKVMYIGADVTHpls..ENEPSVV
  57 hcr..ASVMWRLSIALYTKA.GGVPWVL....EDI.....HPQTAFIGIDYAMrrvqdDGPRFAI
  58 nk...AQLAWRLSIALYVKA.GGIPWKL....APLvgv..PADTAYIGLAYALkrvn.DETHFVT
  59 nny..SYILNQVIPGILAKL.GNLPFILa...KPL.....EIADYFIGLDISRtp6rkSGSLNVC
  60 r18sdQYRANNILLGLLAKA.GWQAVGL....PLLnne..YAADLVIGFDAGR.....NETLSYG
  61 yq...STYYNNLAAGVFSKG.GGVLCAId...DMP.....GETDLFIGLDLGGv....--SQRAP
  62 a18vkATRAWNLLNALFYKA.GKVPWRLlp..DQA.....EYRTSFLGIGFYRdl...DGQQLWT
  63 a18deAGRSWNLLTTLYYKG.SGRIPWR....RLPkeg..EFRACYIGISFYRdv...SGQQLWT
  64 rr8fdAMTYAQMAMKINIKL.GGSNHKLskkd---sq8knNVPIFILGADVTHptgeiNSESVSI
  65 r10ldLFVRHNLLFQVLSKL.GVKYYVL....DYR.....FNYDYIIGIDVAPmk...RSEGYIG
  66 r10ldLFVRHNLLFQVLSKL.GVKYYVL....DYR.....FNYDYIIGIDVAPmk...RSEGYIG
  67 r10ldLFVRHNLLFQVLSKL.GVKYYVL....DYR.....FNYDYIIGIDVAPxk...RSEGYIG
  68 rga..DQMFGNLGLKINLKL.GGVNHKI....EDSll6vaQGKTMIVGIDVAHppagaAVTASIA
  69 dk...GYMTNNLLIQIMGKL.GIKYFIL....DSK.....TPYDYIMGLDTGLgi...FGNHRVG
  70 a18drADLAWNLMTTLYYKG.SGKVPWR....RLPeeg..EFTACYIGISFFKda...ETDEIWT
  71 nl...KFVLLNVAEQVLAKT.GNIPYKLk...EIE.....GKVDAFVGIDISRitrd.GKTVNAV
  72 a18spATRTWNLLNGLFYKA.GKVPWRLy...EPR.....DYTTNFLGIGFHRsl...DGQQLWT
  73 nl...KFVLLNVAEQVLAKT.GNIPYKLk...EIE.....GKVDAFVGIDISRitrd.GKTVNAV
  74 a17deATRAWNFHTALYYKA.NYRPWRIvr..DPS.....EFQACFVGISFYRsl...DQATLVT
  75 a18dqASRTWNLLTTLYYKG.SGRVPWR....RAPqeg..EFSACYIGVSFYRea...GGQQLFT
  76 erkq.DQYFSNVALKVNTKL.GGMNHLL....EPNam6ltKKKTMMVGIDVTHpg6srEGTPSIA
  77 s....EDTLYNILLGIYVKA.GLQPWIL....GEP.....LHSDCFVGLDVSH.....ENGKHAA
  78 gtqerCIVAWNLVVGMLYKCqKGHPWKL....THL.....EENTCYVGISFFNek...GKETRRA
  79 tg9ddATRAWNFCTALYYKGnKTIPWRLve..ETH.....KPKTCYVGIGFYKsr...DNETVST
  80 .....---------------.-------....---.....-------------.....-------
  81 kl...AYPLNSIALACYAKL.GGIPFVI....AAPrt...LAHELVIGIGSAHvk6rlTEPERVV
  82 .....GYLRNVAITKVLLTN.ERWPFVI....STP.....LHADFTVAFDVQL.....N-----T
  83 .....---------------.-------....---.....-------------.....-------
  84 .....---------------.-------....---.....-------------.....-------


      190       200                  210             220       230     
       |         |                    |               |         |     
   1 GAACAVGGDGGHLL.....WTLPEA.Q.....AGERIP.QEVVW.....DLLEETLWAFRRKA.G
   2 AVVASQDWPEITKY.....AGLVCA.Q.....AHRQEL.IQDLFk13tgGMIKELLIAFRRST.G
   3 AVVASQDWPEITKY.....AGLVCA.Q.....AHRQEL.IQDLFk13tgGMIKELLIAFRRST.G
   4 AVVASMDWPEITKY.....RGLVSA.Q.....PHRQEI.IEDLFs12ngGMIRELLIAFRKKT.G
   5 AVVASQDWPEITKY.....AGLVCA.Q.....AHRQEL.IQDLYk13sgGMIKELLISFRRAT.G
   6 AVVASQDWPEITKY.....AGLVSA.Q.....AHRQEL.IQDLYk13tgGMIKELLISFRRAT.G
   7 AVVASQDWPEVTKY.....SGLVCA.Q.....AHRQEI.IQDLYt13hgGMIKELLMSFRRAT.G
   8 SFVASYNQSMTLWY.....SK-VIF.Q.....EKGQEI.VDGLK.....CCLVDALTHYLRSN.G
   9 SFVASYNQSMTLWY.....SK-VIF.Q.....EKGQEI.VDGLK.....CCLVDALTHYLRSN.G
  10 LVVASMDWPEITKY.....RGLVSA.Q.....PHRQEI.IEDLFs12ngGMIRELLIAFRKKT.G
  11 AVVASQDWPEITKY.....AGLVCA.Q.....AHRQEL.IQDLFk25niFVIGELLIAFRRST.G
  12 AVVASMDWPEITKY.....RGLVSA.Q.....PHRQEI.IEDLFs12ngGMIRELLIAFRKKT.G
  13 AVVASMDWPEITKY.....RGLVSA.Q.....PHRQEI.IEDLFs12ngGMIRELLIAFRKKT.G
  14 AVVASMDWPEVTKY.....RGLVSA.Q.....HHREEI.IQDLYk13hgGMIRELLIAFRRST.G
  15 AVVASQDWPEITKY.....AGLVCA.Q.....AHRQEL.IQDLFk13tgGMIKELLISFRRAT.G
  16 AVVASQDWPEVTKY.....AGLVSA.Q.....AHRQEL.IQDLFk13tgGMIKELLISFKRAT.G
  17 GLVCSMNRSLTRWY.....SD-VCF.Q.....SPGQEL.IDGLK.....MLLIKGIRKWHDVN.N
  18 GFVASMDKTFTEWY.....SVAAMQ.R.....STHQEL.MKSMQ.....DAFHKVVTQFKLKN.G
  19 ALVATMNDFHTSYF.....SCVEPH.Q.....SGEELS.VNFAT.....A-ITKALAKYRAKN.G
  20 AFVASINSSYSQWY.....SKAV-V.Q.....TKREEI.VNGLS.....ASFEIALKMYRKRN.G
  21 ALVATMNDSHTSYF.....SCVEPH.E.....SGEELS.VHFAT.....G-ITKALAKYRAKN.G
  22 AFIASLDKMLTSWH.....SR-VCL.Q.....APHQEL.VDLLS.....QCLVSAINVYREKN.G
  23 ALVASMDLQQNSTY.....FSTVSE.C.....SAFDVL.ANNLW.....PMMAKALRQYQREH.Q
  24 ALVASMDLQQNSTY.....FSTVSE.C.....SAFDSL.SNNLW.....PMIAKALRQYQREH.H
  25 AVVASMDWPEINKY.....RGLVSA.Q.....AHREEI.IQDLYk13hsGLIREHFIAFRRAT.G
  26 AVVASMDWPEINKY.....RGLVSA.Q.....AHREEI.IQDLYk13hsGLIREHFIAFRRAT.G
  27 ALVSTMNDAHTSYF.....SCVEPH.E.....SGEELS.VHFAT.....G-ISKALAKYRAKN.G
  28 ALIASMDLQQNSTY.....FSTVTE.C.....SAFDVL.ANTLW.....PMIAKALRQYQREH.K
  29 AVVASMDWPEITKY.....RGLVSA.Q.....SHRQEI.IEDLFs12ngGMIREFLIAFRKKT.G
  30 AFVGSLDAAFTHWY.....SRA-TV.Q.....ERKEEI.LNGLC.....VSLEKTLQAYQRRN.C
  31 AVVASMDWPEITKY.....RGLVSA.Q.....SHRQEI.IEDLFs12ngGMIREFLIAFRKKT.G
  32 AVVASMDWPEITKY.....RGLVSA.Q.....SHRQEI.IEDLFs12ngGMIREFLIAFRKKT.G
  33 GFVSSINQELTQWF.....SQCI-F.Q.....ESGQEL.VNGLK.....TCLEAALKLWCKHN.Q
  34 SFVSTEDEFFSKYM.....TQSIEM.E.....TGVEFS.FSLCP.....VLVKSLQSFCGDRN.G
  35 SFVSTEDEFFSKYM.....TQSVEM.E.....TGVEFS.FSLCP.....VLVKSLQSFCGDRN.G
  36 ALVASLDQNFARYY.....SAVSVH.A.....AGEELS.NHFAQ.....LLGNAVMEFYKVNK.N
  37 GAACAVGGDGGHLL.....WTLPEA.Q.....AGERIP.QEVVW.....DLLEETLWAFRRKA.G
  38 GAACAVGGDGGHLL.....WTLPEA.Q.....AGERIP.QEVVW.....DLLEETLWAFRRKA.G
  39 SFVSTEDEFFSKYM.....TQSIEM.D.....SGVEFS.FSLCP.....ILVKSLESFTSDNR.T
  40 ALTASMNQTATKYW.....STNVIQ.S.....ELGQEA.SHALN.....QGMTKACEAFKKQN.G
  41 TSAFAILANGQSLG.....WELPDI.Q.....RGETFS.GQSIW.....QVVSKLVLKFQDNY.D
  42 TSAFAVLANGQSLG.....WELPDI.Q.....RGETFS.GEAIY.....QTVSKLVNRFYNKF.H
  43 CCSQVFDAEGAGLE.....FVAYDA.Hei7rdNPFMSR.TEMFR.....VMGRSLDLYRRRHS.G
  44 GCSHIYNAQGQGLR.....YKLSKV.Ehp7kkKNPYLN.FEEAY.....KFGMDILALFQDAM.E
  45 CCSQVFDAEGSGLE.....FVAYDA.Hev7reNPFLSR.TEMFR.....VMTRSVDLYRRRHA.G
  46 AAVTASMDTKCYIY.....NIELSI.Q.....TPKKEM.IVQFE.....DIMVDHFHAFKKSQ.G
  47 ASAFAVLADGQSLG.....WELPAV.Q.....RGETFS.GDAIY.....QTVSKLVDRFYDKL.S
  48 GLIQVIGKDGRVLK.....SKTISShQ.....SGEKIQ.INILK.....DIIFEAKQAYKNTY.N
  49 TSAFAVLADGQSLG.....WELPAV.Q.....RGETFS.GQAIW.....QTVSKLIIKFYQIC.Q
  50 ASVRLYGKQGEFVR.....CRVEDS.L.....TEGEEI.PQ---.....----RILENCLPQA.E
  51 TSAFAVLADGQSLG.....WELPAV.Q.....GGETFS.GQAIW.....QTVSKLIIKFYQIC.Q
  52 GCSHIYNAKGQGLR.....YKLSKV.Eqp7gkKNPYLT.YEEAF.....KFGITIRELFVKSM.D
  53 ASVRLYGKQGEFVR.....CRVEDS.L.....TEGEEI.PQ---.....----RILENCLPQA.E
  54 ASVVGSEDAIFNSF.....PGSLRV.Q.....GGGQEV.IAEIK.....DMVYERLENFHKKV.G
  55 AFCSTTDKYFSRYY.....SQVISS.G.....EFSIHL.QQAL-.....---KASLQAFKQQN.N
  56 GVAALYDLTGFRYN.....CS-VRL.Q.....GARDEM.IRDLE.....NIVQRQLLLYKQYN.G
  57 CCAQVFDAEGSGLE.....FIAYKA.Dgv6ygDNPYLNhAQMLK.....IIARSLTIYQRKHY.G
  58 CCSQVFDMDGGGMQ.....FVAFEA.Kd10arRNPFLS.REDMRa....VIARSLSIYQQRNG.G
  59 ASVRLYGKYGEFIR.....YRLEDA.L.....TQGEEI.DK---.....----RTLERFLPAA.D
  60 TSSFAVLADGQILG.....WELPEA.Q.....KGEILD.PDHVR.....RTVRRIISQFQKMN.G
  61 GLAFLFTREGAQLG.....WQLAEA.Q.....RGERVE.DAVLG.....DLLERSLQAYRQVHlG
  62 STAQMFDERGRGLI.....LRGARA.QtetrgRHPYLT.AKDAE.....DLVVQSIAAYKAHH.R
  63 SAAQMFDERGRGFI.....LKGKRA.QtesrgRHPYMT.EEDAY.....ELVKGALKAYRDHH.K
  64 ASIVGSEDGIFNKF.....PGSVRI.Q.....TGGQEV.IADVK.....SMVLERLENFHKKI.G
  65 GSAVMFDSQGYIRK.....IVPIKI.G.....EQRGES.VDMNE.....FFKEMVDKFKEFNI.K
  66 GSAVMFDSQGYIRK.....IVPIKI.G.....EQRGES.VDMNE.....FFKEMVDKFKEFNI.K
  67 GSAVXFDSQGYIRK.....IVPIKI.G.....EQRGES.VDXNE.....FFKEXVDKFKEFNI.K
  68 AMVASIDSNLAQWP.....GEIGIQ.S.....QARKEQ.VDALT.....SMLQSRLRIWKAKNkD
  69 GCTVVYDSEGKIRR.....IQPIET.P.....APG---.-ERLH.....LPYVIEYLENKANI.D
  70 SAAQMFDERGRGFI.....LRGGPA.QsesrgRHPFLT.IDEAH.....KLTESALAAYKSVH.R
  71 AFTKIFNSKGELVR.....YYLTSY.P.....AFGEKL.TEKAI.....GDVFSLLEKLGFKK.G
  72 STAQMFDETGHGLI.....LRGARA.QtetrgRRPYLT.RADMK.....ALVLDALRSYKEHH.K
  73 AFTKIFNSKGELVR.....YYLTSY.P.....AFGEKL.TEKAI.....GDVFSLLEKLGFKK.G
  74 SMAQVYDERGEGVI.....VRGKAV.EllkddRQPHLS.RNDAY.....LLLTTALKEYRREH.R
  75 SAAQMFDERGRGFI.....LKGKGA.QtesrgRHPYLT.QDDAK.....TLIADALAAYKKHH.M
  76 AVVANVDDNFVQFP.....ASLRIQ.Q.....HSKKEM.LDELR.....DMLVERLIVYEKKN.K
  77 GIIQIIGKDGAMIK.....QKALSTsE.....AGEKIS.SETMR.....EIVYDTLHAFEEQY.G
  78 SLAQIFLDTGESFVlr7fnWTNMKH.P.....KSPHLS.KDDAY.....NLMNYVLEHYRSIR.R
  79 SLAQVFDEFGHGVI.....LRGAPV.QldkrdRRPYMN.EEQAF.....ELLMNALNEYDHAL.M
  80 --------------.....------.-.....------.-----.....-PKEQALNKYRCKN.G
  81 GITTVFSADGNYLL.....WNTSRE.A.....DYDDYP.RELLL.....SLRDCIDTIKNRNA.W
  82 ACFTFIGKSGSDIR.....TVLKTS.N.....QKERLS.KAQVR.....QTLLEVLRQEVGFG.R
  83 ---TAVDEYEGGLM.....LTLD--.S.....THRVLR.TQTVL.....SLIKEVVQTEGANW.K
  84 ---TAVDEYEGGLM.....LTLD--.S.....THRVLR.TQTVL.....SLIKEVVQTEGANW.K


            240       250       260               270       280        
             |         |         |                 |         |        
   1 .RLPS..RVLLLRDGRVPQDEFALALEALARE.....GI.A.Y.DLVSVRKSGGGRVYPVQ....
   2 .HKPL..RIIFYRDGVSEGQFYQVLLYELDAIr11gyQP.P.V.TFVVVQKRHHTRLFAQNh10r
   3 .HKPL..RIIFYRDGVSEGQFYQVLLYELDAIr11gyQP.P.V.TFVVVQKRHHTRLFAQNh10r
   4 .RRPE..RIIFYRDGVSEGQFSHVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
   5 .QKPQ..RIIFYRDGVSEGQFYQVLLYELDAIr11nyQP.P.V.TFVVVQKRHHTRLFANNh10k
   6 .QKPQ..RIIFYRDGVSEGQFYQVLLFELDAIr11nyQP.P.V.TFVVVQKRHHTRLFANNh10r
   7 .QKPQ..RIIFYRDGVSEGQFYQVLLYELDAIr11nyQP.P.V.TFVVVQKRHHTRLFANNh10r
   8 .QLPD..RIIIYRDGVGDGQLKLLQQYEIPQMk11nyQP.T.L.TYVVVQKRINTRIFLKSrdgy
   9 .QLPD..RIIIYRDGVGDGQLKLLQQYEIPQMk11nyQP.T.L.TYVVVQKRINTRIFLKSrdgy
  10 .RRPE..RIIFYRDGVSEGQFSHVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
  11 .HKPL..RIIFYRDGVSEGQFYQVLLYELDAIr11gyQP.P.V.TFVVVQKRHHTRLFAQNh10r
  12 .RRPE..RIIFYRDGVSEGQFSHVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
  13 .RRPE..RIIFYRDGVSEGQFSHVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
  14 .YKPS..RIIFYRDGVSEGQFSQVLLHEMDSIr11gyLP.P.V.TFVVVQKRHHTRFFPSDh10r
  15 .QKPQ..RIIFYRDGVSEGQFYQVLLFELDAIr11nyQP.T.V.TFVVVQKRHHTRLFASDh10r
  16 .QKPQ..RIIFYRDGVSEGQFYQVLLYELDAIr11nyQP.P.V.TFVVVQKRHHTRLFANNh10r
  17 .ALPE..RIIVYRDGVGDGQLKVVAGYEVQQFe11syKP.K.L.AVLVVQKRINTRIFSAEprl.
  18 .LLPE..KIIIYRDGVSDGDLKQVEEIELSDLi11qyNP.M.V.SLIIVQKRINTRVFQYVneky
  19 .SLPT..SIIVYRDGVGEGQISHVHKTEVKLLq17pkSV.P.F.AFVIVTKRISARFFAPSkrgm
  20 .KLPT..NIIIYRDGIGDGQLYTCLNYEIPQFem6gnRI.K.I.SYIVVQKRINTRIFSGSgihl
  21 .SLPT..SIIVFRDGVGEGQISHVHKTEVKLLq11pkSV.P.F.AFVIVTKRISARFFAPSkrgm
  22 .QYPD..RIFIYRDGVGDGQLETVKNYEVRQFl11ayKP.K.L.SVIIVQKRVNTRIFEKKrql.
  23 .KLPT..RILFYRDGVSSGSLKQLFEYEVKDIv14sgPP.M.L.AYIVVTKSSNTRFFRNG....
  24 .KLPT..RIMFYRDGVSPGALKQLFEFEVKEIv14cgPP.M.L.AYIVVTKSMNTRFFNNG....
  25 .QIPQ..RIIFYRDGVSEGQFSQVLLHEMTAIr11nyVP.R.V.TFVIVQKRHHTRLFPEQh10k
  26 .QIPQ..RIIFYRDGVSEGQFSQVLLHEMTAIr11nyVP.R.V.TFVIVQKRHHTRLFPEQh10k
  27 .ALPT..SIIVYRDGVGEGQISHVHKTEVRLLq11asSV.P.L.AFVIVTKRISARFFAPSnrgp
  28 .KLPS..RIVFYRDGVSSGSLKQLFEFEVKDIv14lsPP.Q.L.AYIVVTRSMNSRFFLNG....
  29 .RRPE..RIIFYRDGVSEGQFSRVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
  30 .HLPD..RIIIFRDGVSDEQTNICLDYEIPQLq11dyEP.K.I.TFIVVQKRIITRLFTMSrg9g
  31 .RRPE..RIIFYRDGVSEGQFSRVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
  32 .RRPE..RIIFYRDGVSEGQFSRVLLHEMDAIr11gyLP.P.V.TFVVVQKRHHTRLFPEVh10k
  33 .FLPQ..AIIVYRDGVGDGQLQALMDHEVPQIe12dsGV.K.L.TFIVVKKRINTRFFVESqgrl
  34 .PLPS..RIIIFRDGVSNSQAKTVIETEVAQFr15dkPI.K.L.IVLSVNKKVGAKFYAGErnl.
  35 .PLPS..RIIIFRDGVSNSQAKTVIETEVAQFr15dkPI.K.L.IVLSVNKKVGAKFYAGErnl.
  36 .RLPS..KIIIYRDGVGEGQLPFVYDYEVTQVr12peHI.K.L.AFIIVTKRLNTRFFLNK....
  37 .RLPS..RVLLLRDGRVPQDEFALALEALARE.....GI.A.Y.DLVSVRKSGGGRVYPVQ....
  38 .RLPS..RVLLLRDGRVPQDEFALALEALARE.....GI.A.Y.DLVSVRKSGGGRVYPVQ....
  39 .PLPS..RIIIFRDGVSNSQAKTVIETEVAQFr15nkPI.K.L.VVLSVNKKVGAKFYAGErnl.
  40 .RFPE..RVIFYRDGVGEGQVQGICKPEVDQIk10ipDT.Q.L.IYINVCKRVNTRIFAGDvgaf
  41 .SYPK..KILLMRDGLVQDGEFEQTIRELTHQ.....GI.D.V.DILSVRKSGSGRMGRELts9t
  42 .RYPR..KVLLMRDGLVQRGEFDKTIEELRKE.....KI.A.V.DIVGVRKSGTVRMGREEkgsy
  43 .RSPR..RVTVHKTTEFKKDEIDGCMEALHLC.....E-.A.V.DLVQVVEDIGWRGVRIDr12t
  44 .KLPQ..RVVVHKRTPFKNDEIKGITNALKQA.....GIsE.I.DLITITQEYDLKFIAEKi10d
  45 .RSPR..RVMVHKTTEFKQDEIDGCMEALHLC.....E-.A.V.DLVQIVEDVGWRGIRIDl12a
  46 .ILPK..KVFVFRDGVSEGQFAEVMKSELTGLh12naKP.E.V.LFILVQKRHHTRFFLPGnnar
  47 .RYPS..KVLLMRDGLVQGGEFSRTIEELEKE.....KI.A.V.DIVGIRKSGTGRMGIEEgkgk
  48 .KKLE..HIVFHRDGINREDI-DLLKEITNSL.....EI.K.F.DYVEVTKNINRRMAMLEk15k
  49 .RYPQ..KLLLMRDGLVQEGEFQQTIELLKER.....KI.A.V.DVISVRKSGAGRMGQEIye8v
  50 .LKNQ..TVLIYRDGKFQGKEVENLLARARAI.....NA.K.F.ILVECYKTGIPRLYNLQqkqi
  51 .RYPQ..KLLLMRDGLVQEGEFQQTIELLKER.....KI.A.V.DVISVRKSGAGRMGQEIye8v
  52 .KLPR..RVVIHKRTPFRNEEIEGITHALSQA.....GI.KdI.DLITINYEYNAKFIAQRv10d
  53 .LKNQ..TVLIYRDGKFQGKEVDNLLARARAI.....NA.K.F.ILVECYKTGIPRLYNFEqkqi
  54 .KLPS..KVLFYRDGVSEGQYYTVLKEELPKVk15kfNP.K.I.TFMIVVKRHQTRFIPLSe17a
  55 .VYPT..QIIIYRDGVGEGQQPTVLGNELPQFq11rdQT.K.L.TFVICNKRVSGKFYTGGqtrp
  56 .ALPE..RIMYYRDGVSDGQFAEILTIELQALh11gyKP.A.V.TFIVVQKRHHTRFFPQPgc8k
  57 .DLPK..RVVIHKNTPFRDEEVDGCLNALSSV.....D-.A.V.ELIQVQQDTGWRGYRVDaa7a
  58 .ILPR..RMVIHKSNAFKEDEVLGARDALTAVp10ssRP.T.W.RGVWLVKSSGGTAPTQPar..
  59 .LSGK..TVLIYRDGRFCGDEIKHLRERAKAM.....GS.K.F.ILVECIKSGIPRLYEVQe12i
  60 kQSPK..RILLMRDGLIQQQEFSLITEALEEG.....EI.K.Y.DLISVRKSGAGRIGRRNsdgt
  61 .ALPR..RIALHRDGRLFESL-DVIRNFERDY.....SV.R.V.DVLEVVKSGCPPLYRRGvv9a
  62 .HVPA..RLVVLKTSRFRSEEAEGIDAALGKS.....GI.E.MsDLVWVQESSPIAIFRDGn...
  63 .HSPA..RVIILKTSRFRDDEADGILRALEEA.....ET.E.LrDLVWVQESYDAKILRDGd...
  64 .KLPS..KVLFYRDGVSEGQYTTILKEELTKIk16kySP.T.I.TFMIVVKRHHTRFIPIHd17s
  65 .LDNK..KILLLRDGRITNNEEEGLKYISEMF.....DI.E.V.VTMDVIKNHPVRAFANM....
  66 .LDNK..KILLLRDGRITNNEEEGLKYISEMF.....DI.E.V.VTMDVIKNHPVRAFANM....
  67 .LDNK..KILLLRDGRITNNEEEGLKYISEXF.....DI.E.V.VTXDVIKNHPVRAFANX....
  68 .ALPE..NILVYRDGVSKGQYAMVQGMEIPLLe12rkMP.N.M.TVVVVGKRHHTRFYPTStg8v
  69 .MENK..NILFLRDGFIQNSERNDLKEISKEL.....NS.N.I.EVISIRKNNKYKVFTSD....
  70 .TMPA..RVIVMKTSRFREDEAEGVGKALDEA.....GV.E.LrDLVWIHESYSVKVLRDGd...
  71 .---S..KIVVHRDGRLYRDEVAAFKKYGELY.....GY.S.L.ELLEIIKRNNPRFFSNE....
  72 .ALPA..RLVVLKTSHFRDEEADGVDDALEEL.....DV.S.McDMVWVQESSPISLLRNGs...
  73 .---S..KIVVHRDGRLYRDEVAAFKKYGELY.....GY.S.L.ELLEIIKRNNPRFFSNE....
  74 .HLPA..RVVVHKSSKYSKDELEGFNGAVDDQ.....GL.E.T.ADFMVVTKSFTRLFREGt...
  75 .NYPA..RVIVLKTSRFRDEEADGIFEALDEV.....GT.E.LrDLVWVQESSFVKVFRDGn...
  76 .GLPA..RIFVFRDGVSEGQFDTVLQEELAQI.....LE.A.F.KKLSTKARGSAYRPSLSi17r
  77 .HAPK..HITFHRDGFGREDL-TLIDSILSPR.....EI.Q.F.DYVEILKNINRRMAIHEde..
  78 .QNPN..RVVVHKSSNFWNDELEGFREATKNV.....-P.Q.K.DFITILESSLKLFTQGR....
  79 .QMPA..RIVIHKSSNFREEEIRGFTRAIESK.....GI.R.MkDFVTVMESKVRLYSYEQ....
  80 .KLPT..SIVVYRDGVGEGQISHVQKTEVRLMq11asSV.P.F.AFVIVTKRISARFFAPSnrgp
  81 .QAGDelRLVFHVFKPLKDVEATAVKKLVEGLtqtyaKV.E.F.AFVHVSTDHDWVMFDRTs16g
  82 .RTMQ..TIVVQRDGKLFASEIAGAKDAIEIVkk8psDV.S.L.NFIEIPKSSVAPFRLFDs11m
  83 .RKMT..DILIG--------------------.....--.-.-.--ASVMTTYNKKLFRVDt12t
  84 .RKMT..DILIG--------------------.....--.-.-.--ASVMTTYNKKLFRVDt12t


          290               300            310       320               
           |                 |              |         |               
   1 .GRLADG...LYVP.....LEDKTFLLLTVH.....RDFRGTPRPLKLVH.....EAGD.....T
   2 sGNILPG...TVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnn...F
   3 sGNILPG...TVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnn...F
   4 sGNILPG...TVVDrqic.HPTEFDFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
   5 sGNILPG...TVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnk...F
   6 sGNILPG...TVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnn...F
   7 sGNILPG...TVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnk...F
   8 .DNPNPG...TVVDhcit.RRDWYDFLIVSQ.....KVTQGTVTPTHYVV.....VYDDsg...I
   9 .DNPNPG...TVVDhcit.RRDWYDFLIVSQ.....KVTQGTVTPTHYVV.....VYDDsg...I
  10 sGNILPG...TVVDrqic.HPTEFDFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
  11 sGNILPGetsTVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnn...F
  12 sGNILPG...TVVDrqic.HPTEFDFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
  13 sGNILPG...TVVDrqic.HPTEFDFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
  14 sGNILPG...TVVDtkic.HPTEFDFYLNSH.....AGIQGTSRPTHYHV.....LYDEnk...F
  15 sGNILPG...TVVDsnic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnk...F
  16 sGNILPG...TVVDskic.HPTEFDFYLCSH.....AGIQGTSRPAHYHV.....LWDEnk...F
  17 .GNPGPG...SVLDhtvt.RKDWNDFFLVSQ.....HVRQGTVTPTHYVV.....VYDTsn...W
  18 .SNPSSG...TVIDntvt.RRNYFDFFLVSQ.....HVRQGTVNPTHYIV.....LKNGcn...L
  19 .ENPRPG...TIIDtvvt.DPTKYDFFLVSQ.....HVRQGTVTPTHYQV.....IEDTlg...L
  20 .ENPLPG...TVVDqhit.KSNMYDFFLVSQ.....LVRQGTVTPTHYVV.....LRDDcn...Y
  21 .ENPRPG...TIIDtvvt.DPTKYDFFLVSQ.....HVRQGTVTPTHYQV.....IEDTlr...L
  22 .GNPPPG...TVVDstit.RRFLYDFYLVPQ.....LVRQGTVTPTHYIV.....LHDGgd...V
  23 .RNPPPG...TVVDnivt.LPERYDFYLVSQ.....AGRQGTVSPTGYNV.....LYSNir...L
  24 .RNPPPG...TVVDdvvt.LPERYDFYLVSQ.....QVRQGSVSPTSYNV.....LYSNir...L
  25 sGNIQPG...TVVDtkic.HPNEFDFYLNSH.....AGIQGTSRPAHYHV.....LLDEng...F
  26 sGNIQPG...TVVDtkic.HPNEFDFYLNSH.....AGIQGTSRPAHYHV.....LLDEng...F
  27 .ENPRPG...TIIDsvvt.DPTKYDFFLVSQ.....HVRQGTVTPTHYQV.....IEDTlr...L
  28 .QNPPPG...TVVDdvit.LPERYDFYLVSQ.....QVRQGTVSPTSYNV.....LYSTmg...I
  29 sGNILPG...TVKDrqic.HPTEFYFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
  30 qANAPPG...TVLDntvt.RRYMFDFFLVSQ.....TVQMGTVTPTHYIV.....LRDDsk...F
  31 sGNILPG...TVKDrqic.HPTEFYFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
  32 sGNILPG...TVKDrqic.HPTEFYFYLCSH.....AGIQGTSRPTHYHV.....LYDEnh...F
  33 .QNPLPG...TVIDvevt.KRQWYDFFIVSQ.....SVKDGTVTPTHYNV.....IHDTvc...F
  34 .DNPPQG...TLIDtei..SNGKDDYYLISQ.....RTTQGTVQPTHYHV.....LVNDmsdepN
  35 .DNPPQG...TLIDtei..SNGKDDYYLISQ.....RTTQGTVQPTHYHV.....LVNDlfdepN
  36 .NNPPAG...TVIDdvit.DPLKYDFFIVSQ.....AVRQGTVAPTAYNV.....LQDStg...L
  37 .GRLADG...LYVP.....LEDKTFLLLTVH.....RDFRGTPRPLKLVH.....EAGD.....T
  38 .GRLADG...LYVP.....LEDKTFLLLTVH.....RDFRGTPRPLKLVH.....EAGD.....T
  39 .DNPSQG...TLIDsei..CNGKDGFYLIAQ.....KTTQGTVQPTYYHV.....LVNDlidepN
  40 .KNPMPG...TVIDatit.EKDTYEFYLIST.....AAKQGLSAPTRYTV.....IYDSvk...E
  41 yDDAEVG...TVIF.....YSATDSFILQTTev6tkTGPLGSARPLRVVR.....HYGN.....T
  42 .RDAAMG...TVIF.....DHERRSFMLVTSqp6ksSVPIGSARPLRVVH.....EHGN.....T
  43 gYPVDRG...TLIP.....LGDRECLLWMHGd11yyQGSRSTPRPIRLVR.....HAGQ.....G
  44 gYPVDRG...TCIK.....LSSRNALLWTHGv12yyQGGRCIPAPLKITK.....YYGH.....G
  45 sFPVSRG...TLIG.....LGSREALLWTHGd12yfQGARSTPRPLRLVR.....HAGH.....G
  46 .FNVDPG...TVVDrdiv.HPRELDFYLVSH.....QAIKGTARPTRYHA.....VCNDgr...I
  47 yKDAKIG...TVVF.....DYSRKSFTLITSqp6kgGNSLGSARPLRAIH.....EHGK.....T
  48 kWITEIG...MCLK.....KENEAYLITTNP.....SENMGMARPLRIKK.....VYGN.....Q
  49 yRDAAIG...SVIL.....QPAERSFIMVTSqpv..SKTIGSIRPLRIVH.....EYGS.....T
  50 .NAPSKG...LALA.....LSNREVILITSQv....SEQIGVPRPLRLKV.....HELGeq...R
  51 yRDAAIG...SVIL.....QPAERSFIMVTSqpv..SKTIGSIRPLRIVH.....EYGS.....T
  52 sYPVSRG...TCIK.....LSSRNALLWTHGv12yyPGGRCIPAPLKITK.....YYGK.....G
  53 .NAPSKG...LAFA.....LSKREVILITSQv....SEQIGVPRPLRLKV.....HELGdq...V
  54 nDNVIPG...TVVDrdit.SIAFFDFYIQSQ.....QALQGTGIPAHYYV.....LHDEns...Y
  55 .ENPLPG...TYVDnpkvvDNEGKEFYLISQ.....MSRSGTVTPTLYKI.....IHNDvq...G
  56 nGNVPPG...TIVDseit.TPDRYEFYLVSH.....AAVQGVAKPTKYVV.....LYDDsn...C
  57 gYPVERG...SLMP.....IGAHEALLWSRGd13yfKEGKGTPEPLLITR.....HAGR.....G
  58 .YPVPRG...TFVP.....RSGTSALLWAAGn12yyQGGKSIPRPLLLTR.....HAGS.....G
  59 lKAPPKG...LALR.....LSSHEVMLVTTEvk...SEKMGLPNPLRLKV.....IPEEgqq..V
  60 yVDAPKG...TVIF.....SGNDKFKIVTSE.....AKAGGSARPLFVVR.....EQGD.....T
  61 fRNPEVG...DAFE.....LPGLDELIIATYsg8ssWGDKVTVRPLRLRK.....RYGE.....T
  62 .YPVLRG...TFVD.....LDGKGLLYTRGSvp6gtFPGLRVPRPLLLVP.....HENSd....S
  63 .YPVLRG...TFVD.....LDGKGLLYTNGSip6gtYPGLYVPRPLLLCP.....HPSSd....S
  64 nENVIAG...TTVDreit.SPAYFDFYVQSQ.....QSLQGTGIPAHYYV.....LHDEnn...Y
  65 .K-----...MYFN.....LGGAIYLIPHKL.....KQAKGTPIPIKLAKkr8gkVEKQ.....S
  66 .K-----...MYFN.....LGGAIYLIPHKL.....KQAKGTPIPIKLAKkr8gkVEKQ.....S
  67 .K-----...XYFN.....LGGAIYLIPHKL.....KQAKGTPIPIKLAKkr8gkVEKQ.....S
  68 kNNVAPG...TVVDrgit.EAHTWDFFLQSH.....EALKGTGRPAHYIVv57st--GGaql..N
  69 .YRI--G...SVFG.....NDGIFLPHKTPFgsn..PVKLSTWLRFNCGN.....EEGL.....K
  70 .FPVLRG...TFVE.....LDGNGLLYTNGSip6gtYPGLYVPNPLLLCP.....HPQSe....S
  71 .-KFIKG...YFYK.....LSEDSVILATYN.....QVYEGTHQPIKVRK.....VYGE.....L
  72 .YPVLRG...TFVE.....LDGKGLLYTRGSvp6stYPGMRVPNPLLLCP.....HKQTd....R
  73 .-KFIKG...YFYK.....LSEDSVILATYN.....QVYEGTHQPIKVRK.....VYGE.....L
  74 .YPPLRG...TMLS.....LDEANHLLYTRGsv7atYPGMYVPRPLKFQI.....AQAD.....T
  75 .YPVMRG...TFVK.....LDGKGLLYTNGSip6gtYPGMYDPKPLLICP.....YKTSd....S
  76 nGNTRPG...TVVDkgvt.GVFDFDFYLQAH.....AGLQGSVKATHYTV.....VYDEns...L
  77 .WKTSQG...LSYT.....KERMGYLLSTNP.....HARVGMAKPLKVVQ.....QTTT.....L
  78 .YPILRG...TLLS.....LEDDTSGFLFSTgf8ntYPGFSIPRALEIRP.....FNLD.....T
  79 .YPPVRG...TLLS.....LSESKAILYTKGav7ktYPGMYVPSPLEIRA.....FEHD.....S
  80 .ENPRPG...TIIDgivt.DPTKYDFFLVSQ.....NVRQGTVTPTYYQV.....IEDTlg...L
  81 hYVPERG...HAVP.....MGKRELLVAVGGpmdlkSALHGVPKPLLLKL.....HPQStf...T
  82 aNNPRIG...SYFI.....ATNYDGYICTTGke...FYHPGTANPLHVKY.....IEGN.....M
  83 fEKTEKG...ETVQ.....ISFIDYYKKNYG.....IEIMDWDQPLLISRdtkr.MPGSd....T
  84 fEKTEKG...ETIQ.....ISFIDYYKKNYG.....IEIMDWDQPLLISRdtkr.MPGSd....T


        330       340          350            360       370       380  
         |         |            |              |         |         |  
   1 PLEALAHQIFHLTRLYPASG...FAFPR.....LPAPLHLADRLVKEVGRLGIRHLKEVDREKLF
   2 TADGLQSLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
   3 TADGLQSLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
   4 TADALQSLTNNLCYTYARCT...RAVSV.....VP-PAYYAHLAAFRARYYVEGESSDG------
   5 TADGLQSLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
   6 TADALQSLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
   7 SADGLQSLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPDTSD-------
   8 TPDQCQRLTYKMCHLYYNWP...G-TVR.....VPAPCQYAHKLSYLVGQCVHAQPSDVLVDKLF
   9 TPDQCQRLTYKMCHLYYNWP...G-TVR.....VPAPCQYAHKLSYLVGQCVHAQPSDVLVDKLF
  10 TADALQSLTNNLCYTYARCT...RAVSV.....VP-PAYYAHLAAFRARYYVEGESSDG------
  11 TADGLQSLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
  12 TADALQSLTNNLCYTYARCT...RAVSVg18vyFP-PAYYAHLAAFRARYYVEGESSDG------
  13 TADALQSLTNNLCYTYARCT...RAVSVg18vyFP-PAYYAHLAAFRARYYVEGESSDG------
  14 TADILQILTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARYYIEGDTSDS------
  15 SADELQSLSNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
  16 TADELQTLTNNLCYTYARCT...RSVSI.....VP-PAYYAHLAAFRARFYMEPETSD-------
  17 KPDIMQKLSYKLTHLYYNWP...G-TVR.....VPAPCQYAHKLAYQVGQSIHGQPSQELCDRLF
  18 SVENIQRLSYKLCHLYYNWC...G-TVK.....VPAPVQYAHKLAYLIGQNVRQKPSDKLCNSLF
  19 PPDIMQRLTFKLTHMYYNWS...G-TVR.....VPAPCQLAHKLAFLTGQTLRHAPHTGLDELLY
  20 GPDIIQKLSYKLCFLYYNWA...G-TVR.....IPACCMYAHKLAYLIGQSIQRDVAEALSEKLF
  21 PPDIMQRLTFKLTHMYYNWS...G-TVR.....VPAPCQLAHKLAFLTGQTLRRAPHTGLDELLY
  22 KTDHMQRFTYKLCHLYYNWP...G-TIR.....VPAPCQYAHKLAYLVGQSIKSEPSHELNNLLY
  23 SPDQIQKLTYKMCHLYYNWS...G-TTR.....VPAVCQYAKKLATFVGTHLHSIPQNALEKKFY
  24 SPDQIQKLTYKMCHLYYNWS...G-TTR.....VPAVCQYAKKLATLVATNLHAIPQNALEKKFY
  25 TADQLQMLTNNLCYTYARCT...KSVSI.....VP-PAYYAHLAAFRARYYMESEMSDG------
  26 TADQLQMLTNNLCYTYARCT...KSVSI.....VP-PAYYAHLAAFRARYYMESEMSDG------
  27 PPDIMQRLTFKLTHMYYNWS...G-TVR.....VPAPCQLAHKLAFLTGQSLRRSPNIGLDELLY
  28 SPEKMQKLTYKMCHLYYNWS...G-TTR.....VPAVCQYAKKLATLVGTNLHSIPQNALEKKFY
  29 TADELQTLTNNLCYIYARCT...HAVSV.....VP-PAYYSHLAASHAHCCIKGHSS--------
  30 SPDILQQLSYKMCYMYYNWT...G-TIR.....VPACCQYAHKLAYLVGQSVKRMPAESLNDKLF
  31 TADELQTLTNNLCYIYARCT...HAVSV.....VP-PAYYSHLAASHAHCCIKGHSS--------
  32 TADELQTLTNNLCYIYARCT...HAVSV.....VP-PAYYSHLAASHAHCCIKGHSS--------
  33 TPDRIQYLTYRLCHMYYNLP...G-VIR.....VPAPCHYAHKLAYLVGQSIHQEPHHSLASRLF
  34 ILKKLQSLSYKLCYMYYNFS...G-AIK.....IPAPIQYAHVCSNFIGDRFDPRKPQS------
  35 ILKKLQALSYKLCYMYYNFS...G-AIK.....IPAPIQYAHVCSNFIGDRFDPRKPQS------
  36 KADQMQRLTYKLCHMYYNFS...G-TVR.....VPAPCQYAHKLAFFVSQTIKQPAHPQLSTTLY
  37 PLEALAHQIFHLTRLYPASG...FAFPR.....LPAPLHLADRLVKEVGRLGIRHLKEVDREKLF
  38 PLEALAHQIFHLTRLYPASG...FAFPR.....LPAPLHLADRLVKEVGRLGIRHLKEVDREKLF
  39 ITNKLQALAYKLCYMYYNFS...G-AIK.....IPAPIQYAHVCSNFIGDRFDPRKPQ-------
  40 TPDLIELLTYKLCYTYYNVS...G-AIK.....EPSCIRYAHRLAALIGERGGKNKEP-------
  41 PLELLALQTYHLTQLHPASG...FRSCR.....LPWVLHLADRSSKEFQRIGQISLL--------
  42 PLEVLAIQTYHLSQLHPASG...FQACR.....LPWVLHFADKSSKEFQRIG-------------
  43 PWDETARSALALAKMDWNND...ALYDM.....LPVTMAYAKTLARVVKRMDGLGSAPYQFRFF-
  44 DLETIAKEILGFTKMNWNSF...NLYTK.....LPATIDTSNTLAQVGNLLRQYNGVTYDYRFF-
  45 SWDEAALAILALTKMNWNND...ALYDP.....LPVTIGYSKVLARVVKRMSGLGSAPYQFRFF-
  46 PENEVEHLAYYLCHLYARCM...R-AVS.....YPAPTYYAHLACLRARSLTYGEIF--------
  47 PLEVLALQTYHLSQLHPASG...FQACR.....LPWVLHFADKSGKEFQRLGDN-----------
  48 NMDDIVKDIYKLSFMHIGSI...M-KSR.....LPITTYYADLSSIYSHRELMPKSVDNNI----
  49 DLELLALQTYHLTQLHPASG...FRSCR.....LPWVLHLADRSSKEFQRIGQISV---------
  50 NLKQLVDTTLKLTLLHYGSL...K-DPR.....LPIPLYGADIIAYRRLQGIYPSLLEDDCQFW-
  51 DLELLALQTYHLTQLHPASG...FRSCR.....LPWVLHLADRSSKEFQRIGQISV---------
  52 DLSTIASEIIGFTKMNWNSF...NLYTK.....LPATIDTSNTLAQVGNLLHQYNGATYDYRYF-
  53 NLKQLVDTTLKLTLLHYGSL...K-EPR.....LPIPLYGADAIAYRRLQGICPSLLEDDCQFW-
  54 TSDEIQRITYNLCHTFGRAT...KSVKV.....VP-AAYYADLLCTRGRCYVGPPSRDA------
  55 NENDIKVLTFKLCWLYYNFT...G-PIK.....IPAPVRYAHCLCNFIGDHY-------------
  56 HPDSLQALTYNLCHLFARCN...R-AVS.....YPAPTYYAHLAAYRGRVY--------------
  57 DFGDVCSDTLGLTKMDWNND...GPYDG.....MPVTLNYAGRLAQIVKRMPDLQPHPYPVRLF-
  58 PLETIAHETLALTKMDWNND...ALYDP.....VPVSIRYSQKLARTISNVQDLPGNSYPYRLF-
  59 SLESLVEATLKLTLLHHGSL...K-EPR.....LPIPLYGSDIIAYRRLQGISPGELDGDRQFW-
  60 PIEIIAEQFYRLTQLHPVSG...SFTSR.....LPMPLNYADKLAKKIQSLGSVGILQNLDRKKL
  61 DLHTLARQVVLLSRIHGASL...YRHPR.....LPVTTHHADRFATLRQECNLDDLSKMDRLCPV
  62 TILTLAKDVLALTKVNWNTT...QFDQK.....LPAPIKAAREVGRILKHVEFGTAVSSDFR---
  63 TAAQIAEEVFSLTKINWNST...QMNQR.....LPVPIRAARKVGEVLKYIPDGQSISSDYRR--
  64 TSDTIQKITYDLCHTFSRAT...KSVKV.....VP-AAYYADLLCTRGRDYIYGFAKD-------
  65 ITRQDVLDIFILTRLNYGSI...SADMR.....LPAPVHYAHKFANAIRNEWKIKEEFLAEGFLY
  66 ITRQDVLDIFILTRLNYGSI...SADMR.....LPAPVHYAHKFANAIRNEWKIKEEFLAEGFLY
  67 ITRQDVLDIFILTRLNYGSI...SADXR.....LPAPVHYAHKFANAIRNEWKIKEEFLAEGFLY
  68 EVDTLEMLTYSLCNVFGRAT...R-SVS.....YATPAYFADILCERGRC---------------
  69 INESIMQLLYDLTKMNYSALygeGRYLR.....IPAPIHYADKFVKALGKNWKIDEELLKHGFLY
  70 TIEQIAKEVFSLTKVNWNST...QMNQR.....LPIPIRAARKVGDVLKYVPSGQKVSSDYRKY-
  71 PVEVLCSQILSLTLXNYSSF...Q-PIK.....LPATVHYSDKITKLXLRGIEPIKKEGDIXYW-
  72 SITQIAEEILALTKVNWNST...QFDQK.....LPAPIRASREVGRVLKHVAQSGMVRADFRF--
  73 PVEVLCSQILSLTLMNYSSF...Q-PIK.....LPATVHYSDKITKLMLRGIEPIKKEGDIMY--
  74 SPRKLAEEILALTKLNWNNT...QFDGA.....EPITMRVAQQVGKVLKYVPEGDVVQPRYSFY-
  75 TVAQIANEIFGLTKINWNST...QMNQK.....LPIPIRAARKVGEVLKYITDEKVSS-------
  76 TADDIQQGTHTASYLYARAT...KAVSL.....IP-AAYYADLACERGRCYLNDF----------
  77 PFEAILTDVYRLSFMHVHSL...L-KTR.....LPITTHYADLSSTFHNRGL-------------
  78 SLVQVCKEILSFTKLDWNNT...FVYSR.....MPVTISVSRKVGQVMSETEAQKFSELDSHYYF
  79 SLENLCEEVLGLTKMNWNNT...QFDGR.....YPITLECSRKVGEIMKYVEVNQKPQVSYSFY-
  80 PPDIMQRLTYKLTHMYYNWS...G-TVR.....VPAPCQLAHKLAFLTGQSLRRPSNIGLDELLY
  81 DIEYLGRQAFRFTSMSWRNM...Y-PSR.....NPVTISYSDLIAELLGHLRHVRNWN-------
  82 PFEKILEDVYALTCLALTRP...EDCTR.....EPFTMKLADIRLREHAGGYDEDALAYDD----
  83 PTDFMICLIPELCQ------...-----.....--------------------------------
  84 PTDFMICLIPELCQ------...-----.....--------------------------------


        
       
   1 FV
   2 --
   3 --
   4 --
   5 --
   6 --
   7 --
   8 FL
   9 FL
  10 --
  11 --
  12 --
  13 --
  14 --
  15 --
  16 --
  17 FL
  18 FL
  19 FL
  20 YL
  21 FL
  22 YL
  23 YL
  24 YL
  25 --
  26 --
  27 FL
  28 YL
  29 --
  30 YL
  31 --
  32 --
  33 YL
  34 --
  35 --
  36 FL
  37 FV
  38 FV
  39 --
  40 --
  41 --
  42 --
  43 --
  44 --
  45 --
  46 --
  47 --
  48 --
  49 --
  50 --
  51 --
  52 --
  53 --
  54 --
  55 --
  56 --
  57 --
  58 --
  59 --
  60 FF
  61 YL
  62 --
  63 --
  64 --
  65 FV
  66 FV
  67 FV
  68 --
  69 FI
  70 --
  71 --
  72 --
  73 --
  74 --
  75 --
  76 --
  77 --
  78 YM
  79 --
  80 FL
  81 --
  82 --
  83 --
  84 --