PFRMAT SS TARGET T0471 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0471.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0471.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0471.t04.str2.rdb (weight 1.54758) METHOD T0471.t04.alpha.rdb (weight 0.659012) METHOD T0471.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0471.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0471.t2k.str2.rdb (weight 1.54758) METHOD T0471.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0471.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 13.2224 METHOD METHOD ============================================ METHOD Comments from T0471.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 13.2224 METHOD METHOD ============================================ METHOD Comments from T0471.t04.str2.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 13.2224 METHOD METHOD ============================================ METHOD Comments from T0471.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 13.2224 METHOD METHOD ============================================ METHOD Comments from T0471.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 24 METHOD METHOD ============================================ METHOD Comments from T0471.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 24 METHOD METHOD ============================================ METHOD Comments from T0471.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 24 METHOD METHOD ============================================ METHOD Comments from T0471.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0471 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0471.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 24 METHOD METHOD ============================================ MODEL 1 M C 0.85 W C 0.64 N C 0.53 D H 0.77 L H 0.84 A H 0.84 V H 0.82 Y H 0.79 I H 0.78 I H 0.76 R H 0.73 C H 0.66 S C 0.43 G C 0.78 P C 0.85 G C 0.85 T C 0.69 R E 0.65 V E 0.90 V E 0.91 E E 0.91 V E 0.84 G E 0.70 A C 0.54 G C 0.77 R C 0.77 F C 0.74 L H 0.70 Y H 0.83 V H 0.93 S H 0.95 D H 0.95 Y H 0.95 I H 0.95 R H 0.93 K H 0.86 H C 0.58 S C 0.93 K C 0.89 V E 0.55 D E 0.84 L E 0.91 V E 0.91 L E 0.86 T E 0.73 D E 0.51 I C 0.59 K C 0.76 P C 0.82 S C 0.83 H C 0.83 G C 0.72 G C 0.53 I E 0.70 V E 0.73 R E 0.68 D E 0.46 D C 0.59 I C 0.64 T C 0.73 S C 0.86 P C 0.80 R C 0.76 M H 0.58 E H 0.66 I H 0.69 Y H 0.53 R C 0.51 G C 0.73 A C 0.73 A C 0.62 L E 0.84 I E 0.86 Y E 0.85 S E 0.71 I C 0.64 R C 0.86 P C 0.89 P C 0.66 A H 0.72 E H 0.76 I H 0.67 H H 0.69 S H 0.82 S H 0.90 L H 0.94 M H 0.95 R H 0.95 V H 0.94 A H 0.93 D H 0.85 A H 0.72 V C 0.59 G C 0.91 A C 0.88 R C 0.74 L E 0.90 I E 0.92 I E 0.92 K E 0.83 P C 0.55 L C 0.83 T C 0.83 G C 0.83 E C 0.75 D C 0.64 I C 0.63 V C 0.62 T C 0.63 E C 0.66 R C 0.59 K E 0.54 M E 0.65 K E 0.66 L E 0.61 V C 0.58 N C 0.77 Y C 0.72 G C 0.53 R E 0.72 T E 0.83 Y E 0.89 F E 0.89 Y E 0.88 E E 0.83 Y E 0.77 I E 0.62 A E 0.48 E C 0.51 V C 0.57 R C 0.70 S C 0.80 R C 0.92 END