PFRMAT SS TARGET T0459 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0459.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0459.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0459.t04.str2.rdb (weight 1.54758) METHOD T0459.t04.alpha.rdb (weight 0.659012) METHOD T0459.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0459.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0459.t2k.str2.rdb (weight 1.54758) METHOD T0459.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0459.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 212.154 METHOD METHOD ============================================ METHOD Comments from T0459.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 212.154 METHOD METHOD ============================================ METHOD Comments from T0459.t04.str2.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 212.154 METHOD METHOD ============================================ METHOD Comments from T0459.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 212.154 METHOD METHOD ============================================ METHOD Comments from T0459.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 875 METHOD METHOD ============================================ METHOD Comments from T0459.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 875 METHOD METHOD ============================================ METHOD Comments from T0459.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 875 METHOD METHOD ============================================ METHOD Comments from T0459.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0459 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0459.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 875 METHOD METHOD ============================================ MODEL 1 S C 0.67 N C 0.53 A C 0.48 M C 0.46 L C 0.49 R C 0.58 Y C 0.68 G C 0.80 D C 0.82 T C 0.71 E C 0.65 I C 0.63 C C 0.71 I C 0.72 D C 0.70 P H 0.67 S H 0.93 E H 0.95 S H 0.96 V H 0.96 L H 0.95 H H 0.94 L H 0.92 L H 0.80 G H 0.51 K C 0.62 K H 0.60 Y H 0.69 T H 0.86 M H 0.92 L H 0.94 I H 0.94 I H 0.94 S H 0.93 V H 0.92 L H 0.85 G H 0.62 N C 0.63 G C 0.75 S C 0.81 T C 0.86 R C 0.71 Q C 0.55 N C 0.60 F H 0.78 N H 0.88 D H 0.92 I H 0.93 R H 0.88 S H 0.76 S H 0.67 I C 0.66 P C 0.75 G C 0.81 I C 0.73 S C 0.76 S H 0.89 T H 0.92 I H 0.93 L H 0.94 S H 0.95 R H 0.95 R H 0.95 I H 0.95 K H 0.96 D H 0.96 L H 0.95 I H 0.94 D H 0.87 S C 0.66 G C 0.92 L C 0.79 V E 0.64 E E 0.68 R E 0.54 R C 0.66 S C 0.85 G C 0.90 Q C 0.84 I E 0.61 T E 0.84 T E 0.89 Y E 0.89 A E 0.85 L E 0.64 T C 0.81 E C 0.66 K C 0.62 G H 0.53 M H 0.65 N H 0.65 V H 0.86 R H 0.92 N H 0.94 S H 0.95 L H 0.95 M H 0.95 P H 0.96 L H 0.95 L H 0.96 Q H 0.95 Y H 0.93 I H 0.91 S H 0.88 V H 0.79 L H 0.60 D C 0.69 R C 0.76 N C 0.79 G C 0.83 D C 0.90 END