PFRMAT SS TARGET T0457 AUTHOR 4008-1775-0004 METHOD This file is the result of combining several RDB files, specifically METHOD T0457.t06.str2.rdb (weight 1.54425) METHOD T0457.t06.str4.rdb (weight 0.924988) METHOD T0457.t06.pb.rdb (weight 0.789901) METHOD T0457.t06.bys.rdb (weight 0.748322) METHOD T0457.t06.alpha.rdb (weight 0.678173) METHOD T0457.t04.str2.rdb (weight 1.54425) METHOD T0457.t04.str4.rdb (weight 0.924988) METHOD T0457.t04.pb.rdb (weight 0.789901) METHOD T0457.t04.bys.rdb (weight 0.748322) METHOD T0457.t04.alpha.rdb (weight 0.678173) METHOD T0457.t2k.str2.rdb (weight 1.54425) METHOD T0457.t2k.str4.rdb (weight 0.924988) METHOD T0457.t2k.pb.rdb (weight 0.789901) METHOD T0457.t2k.bys.rdb (weight 0.748322) METHOD T0457.t2k.alpha.rdb (weight 0.678173) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0457.t06.str2.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1677 METHOD METHOD ============================================ METHOD Comments from T0457.t06.str4.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-str4-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 21 (1 str4 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1677 METHOD METHOD ============================================ METHOD Comments from T0457.t06.pb.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-pb-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 16 (1 pb ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1677 METHOD METHOD ============================================ METHOD Comments from T0457.t06.bys.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-bys-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 Bystroff ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1677 METHOD METHOD ============================================ METHOD Comments from T0457.t06.alpha.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1677 METHOD METHOD ============================================ METHOD Comments from T0457.t04.str2.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1664 METHOD METHOD ============================================ METHOD Comments from T0457.t04.str4.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-str4-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 21 (1 str4 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1664 METHOD METHOD ============================================ METHOD Comments from T0457.t04.pb.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-pb-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 16 (1 pb ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1664 METHOD METHOD ============================================ METHOD Comments from T0457.t04.bys.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-bys-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 Bystroff ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1664 METHOD METHOD ============================================ METHOD Comments from T0457.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1664 METHOD METHOD ============================================ METHOD Comments from T0457.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 524 METHOD METHOD ============================================ METHOD Comments from T0457.t2k.str4.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-str4-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 21 (1 str4 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 524 METHOD METHOD ============================================ METHOD Comments from T0457.t2k.pb.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-pb-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 16 (1 pb ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 524 METHOD METHOD ============================================ METHOD Comments from T0457.t2k.bys.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-bys-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 Bystroff ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 524 METHOD METHOD ============================================ METHOD Comments from T0457.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0457 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0457.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 524 METHOD METHOD ============================================ MODEL 1 M H 0.49 V H 0.65 E H 0.78 I H 0.87 F H 0.92 N H 0.92 E H 0.92 I H 0.92 M H 0.92 Q H 0.92 R H 0.92 V H 0.90 K H 0.83 E H 0.63 A C 0.59 E C 0.70 T C 0.55 I E 0.74 I E 0.80 I E 0.81 H E 0.78 R E 0.68 H C 0.54 V C 0.61 R C 0.71 P C 0.66 D C 0.71 P H 0.62 D H 0.72 A H 0.82 Y H 0.88 G H 0.91 S H 0.92 Q H 0.92 L H 0.92 G H 0.92 L H 0.92 K H 0.92 L H 0.92 Y H 0.92 L H 0.90 E H 0.84 R H 0.70 K C 0.59 F C 0.74 P C 0.67 E C 0.66 K C 0.53 N E 0.64 I E 0.75 Y E 0.75 A E 0.63 T C 0.59 G C 0.77 E C 0.69 A C 0.69 E C 0.69 P H 0.48 S H 0.53 L H 0.66 S H 0.63 F H 0.47 I C 0.57 G C 0.63 D C 0.66 L C 0.47 D H 0.55 E H 0.49 I C 0.43 D C 0.53 D C 0.51 S C 0.53 V C 0.55 Y C 0.63 S C 0.62 D C 0.65 A C 0.50 L E 0.73 V E 0.80 I E 0.82 V E 0.80 C E 0.76 D E 0.52 T C 0.61 A C 0.64 N C 0.71 A C 0.54 P H 0.50 R C 0.51 I C 0.53 D C 0.57 D H 0.49 Q H 0.60 R H 0.58 Y H 0.51 L C 0.48 N C 0.68 G C 0.79 Q C 0.69 S E 0.53 L E 0.77 I E 0.80 K E 0.80 I E 0.75 D E 0.61 H C 0.56 H C 0.71 P C 0.60 A C 0.65 T C 0.61 D C 0.57 Q C 0.54 Y C 0.64 G C 0.66 D C 0.62 V C 0.53 N E 0.47 F E 0.59 V E 0.57 N C 0.54 T C 0.55 E C 0.59 A C 0.49 S H 0.54 S H 0.72 T H 0.85 S H 0.90 E H 0.92 I H 0.92 I H 0.92 F H 0.92 D H 0.92 F H 0.92 I H 0.91 S H 0.90 H H 0.87 F H 0.81 N H 0.69 D C 0.52 L C 0.64 S C 0.63 I C 0.63 I C 0.67 D C 0.77 E H 0.73 H H 0.86 V H 0.91 A H 0.92 R H 0.92 V H 0.92 L H 0.91 Y H 0.86 L H 0.73 G H 0.55 I H 0.37 V C 0.41 G C 0.49 D C 0.55 T C 0.68 G C 0.74 R C 0.55 F E 0.53 L E 0.56 F C 0.50 S C 0.58 N C 0.69 T C 0.70 S C 0.79 P H 0.62 H H 0.79 T H 0.89 M H 0.91 E H 0.92 V H 0.92 A H 0.92 S H 0.92 Q H 0.91 L H 0.86 L H 0.76 A H 0.54 Y C 0.61 P C 0.67 F C 0.62 N C 0.67 H H 0.67 N H 0.81 A H 0.88 E H 0.89 L H 0.87 N H 0.83 K H 0.68 M H 0.51 S C 0.50 E C 0.56 K C 0.66 D C 0.75 P H 0.69 K H 0.75 L H 0.77 M H 0.83 P H 0.88 F H 0.89 Q H 0.89 G H 0.90 Y H 0.91 V H 0.89 L H 0.84 Q H 0.72 N C 0.46 F C 0.46 E E 0.44 L E 0.47 S C 0.53 D C 0.55 S C 0.68 H C 0.60 E E 0.56 Y E 0.71 C E 0.75 Q E 0.79 I E 0.79 K E 0.74 I E 0.61 T C 0.60 N H 0.61 D H 0.78 V H 0.83 L H 0.86 K H 0.82 Q H 0.66 F C 0.52 D C 0.69 I C 0.68 Q C 0.77 P H 0.47 N H 0.61 E H 0.69 A H 0.81 S H 0.87 Q H 0.89 F H 0.88 V H 0.88 N H 0.87 T H 0.83 V H 0.78 A H 0.70 D H 0.54 I C 0.48 S C 0.72 G C 0.83 L C 0.63 K E 0.62 I E 0.80 W E 0.82 M E 0.82 F E 0.82 G E 0.79 V E 0.74 D E 0.64 E C 0.54 G C 0.76 D C 0.72 Q E 0.62 I E 0.75 R E 0.81 C E 0.83 R E 0.82 I E 0.78 R E 0.70 S C 0.51 K C 0.71 G C 0.82 I C 0.69 T C 0.64 I H 0.72 N H 0.85 D H 0.91 V H 0.91 A H 0.90 N H 0.87 Q H 0.70 F C 0.60 G C 0.78 G C 0.76 G C 0.72 G C 0.65 H C 0.61 P H 0.51 N C 0.46 A C 0.43 S C 0.54 G C 0.49 V E 0.59 S E 0.64 V E 0.50 Y C 0.61 S C 0.70 W C 0.54 D H 0.52 E H 0.79 F H 0.89 E H 0.92 E H 0.92 L H 0.92 A H 0.92 Q H 0.92 A H 0.92 L H 0.92 R H 0.92 Q H 0.91 K H 0.89 L H 0.87 L H 0.83 E H 0.64 H C 0.48 H C 0.56 H C 0.60 H C 0.67 H C 0.69 H C 0.71 END