PFRMAT SS TARGET T0454 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0454.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0454.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0454.t04.str2.rdb (weight 1.54758) METHOD T0454.t04.alpha.rdb (weight 0.659012) METHOD T0454.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0454.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0454.t2k.str2.rdb (weight 1.54758) METHOD T0454.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0454.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2180 METHOD METHOD ============================================ METHOD Comments from T0454.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2180 METHOD METHOD ============================================ METHOD Comments from T0454.t04.str2.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2180 METHOD METHOD ============================================ METHOD Comments from T0454.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2180 METHOD METHOD ============================================ METHOD Comments from T0454.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 5302 METHOD METHOD ============================================ METHOD Comments from T0454.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 5302 METHOD METHOD ============================================ METHOD Comments from T0454.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 5302 METHOD METHOD ============================================ METHOD Comments from T0454.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0454 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0454.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 5302 METHOD METHOD ============================================ MODEL 1 M C 0.90 T C 0.80 R C 0.50 A H 0.72 D H 0.78 C H 0.83 R H 0.95 S H 0.95 R H 0.96 L H 0.96 M H 0.96 E H 0.96 V H 0.96 A H 0.96 T H 0.96 E H 0.96 L H 0.96 F H 0.96 A H 0.94 Q H 0.83 K H 0.48 G C 0.84 F C 0.83 Y C 0.71 G C 0.60 V C 0.56 S C 0.69 I H 0.94 R H 0.96 E H 0.96 L H 0.96 A H 0.96 Q H 0.93 A H 0.88 A C 0.54 G C 0.93 A C 0.90 S C 0.89 I H 0.71 S H 0.80 M H 0.83 I H 0.84 S H 0.77 Y H 0.67 H H 0.50 F C 0.71 G C 0.86 G C 0.88 K H 0.88 E H 0.94 G H 0.95 L H 0.96 Y H 0.96 A H 0.96 A H 0.96 V H 0.96 L H 0.95 Q H 0.94 E H 0.92 Q H 0.90 F H 0.89 A H 0.89 C H 0.89 F H 0.90 G H 0.91 Q H 0.90 L H 0.90 D H 0.88 D H 0.85 I H 0.78 R H 0.67 G C 0.50 Q C 0.68 A C 0.82 G C 0.88 D C 0.88 P H 0.87 L H 0.94 A H 0.95 V H 0.95 M H 0.96 T H 0.96 A H 0.96 Y H 0.96 L H 0.96 R H 0.96 W H 0.95 T H 0.95 I H 0.95 Q H 0.92 R H 0.87 H H 0.79 R H 0.67 N C 0.51 N C 0.71 P H 0.55 Q H 0.71 L H 0.85 L H 0.91 R H 0.92 F H 0.92 Y H 0.92 T H 0.92 S H 0.89 E H 0.83 L H 0.73 T H 0.55 N C 0.61 P C 0.75 T C 0.69 P H 0.79 C H 0.86 F H 0.89 A H 0.92 A H 0.93 I H 0.93 V H 0.92 S H 0.92 P H 0.91 A H 0.88 I H 0.90 A H 0.91 S H 0.92 V H 0.93 I H 0.95 R H 0.95 L H 0.95 L H 0.96 A H 0.96 E H 0.96 S H 0.96 I H 0.96 E H 0.95 A H 0.93 G H 0.90 M H 0.87 T H 0.82 R C 0.55 G C 0.88 L C 0.83 F C 0.75 R C 0.82 R C 0.76 D C 0.83 L C 0.87 H C 0.89 A H 0.92 V H 0.94 N H 0.95 S H 0.96 A H 0.96 L H 0.96 A H 0.96 L H 0.96 A H 0.96 G H 0.96 M H 0.95 V H 0.95 N H 0.93 Y H 0.92 F H 0.93 F H 0.93 L H 0.90 S H 0.87 T H 0.82 L H 0.74 A H 0.58 T C 0.63 E C 0.75 G C 0.78 L C 0.76 T C 0.76 S C 0.76 H C 0.56 S C 0.50 P H 0.74 D H 0.79 Q H 0.85 D H 0.93 E H 0.94 E H 0.95 L H 0.96 I H 0.96 R H 0.96 Q H 0.95 Y H 0.95 V H 0.95 A H 0.94 I H 0.91 F H 0.85 T H 0.73 R C 0.53 G C 0.69 I C 0.66 M C 0.74 A C 0.81 D C 0.82 G C 0.75 G C 0.72 A C 0.73 A C 0.76 P C 0.80 A C 0.88 END