PFRMAT SS TARGET T0449 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0449.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0449.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0449.t04.str2.rdb (weight 1.54758) METHOD T0449.t04.alpha.rdb (weight 0.659012) METHOD T0449.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0449.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0449.t2k.str2.rdb (weight 1.54758) METHOD T0449.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0449.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1138 METHOD METHOD ============================================ METHOD Comments from T0449.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1138 METHOD METHOD ============================================ METHOD Comments from T0449.t04.str2.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1138 METHOD METHOD ============================================ METHOD Comments from T0449.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1138 METHOD METHOD ============================================ METHOD Comments from T0449.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 399 METHOD METHOD ============================================ METHOD Comments from T0449.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 399 METHOD METHOD ============================================ METHOD Comments from T0449.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 399 METHOD METHOD ============================================ METHOD Comments from T0449.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0449 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0449.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 399 METHOD METHOD ============================================ MODEL 1 M C 0.87 D C 0.51 Y E 0.79 T E 0.85 I E 0.81 E E 0.53 N C 0.81 N C 0.86 M C 0.71 I E 0.77 K E 0.91 V E 0.92 V E 0.92 I E 0.87 S E 0.65 D C 0.60 H C 0.72 G C 0.55 A E 0.72 E E 0.88 I E 0.93 Q E 0.88 S E 0.92 V E 0.91 K E 0.86 S E 0.70 A C 0.80 H C 0.88 T C 0.78 D C 0.54 E E 0.70 E E 0.78 F E 0.78 M E 0.69 W E 0.52 Q C 0.59 A C 0.75 N C 0.82 P C 0.72 E C 0.66 I C 0.61 W C 0.64 G C 0.71 R C 0.78 H C 0.80 A C 0.74 P C 0.63 V E 0.63 L E 0.67 F E 0.61 P E 0.47 I C 0.56 V C 0.64 G C 0.72 R C 0.68 L C 0.67 K C 0.80 N C 0.89 D C 0.84 E E 0.51 Y E 0.83 T E 0.79 Y E 0.65 K C 0.88 G C 0.89 K E 0.59 T E 0.81 Y E 0.78 H E 0.63 L C 0.62 G C 0.72 Q C 0.69 H C 0.65 G C 0.61 F C 0.52 A C 0.52 R C 0.60 N C 0.75 A C 0.75 D C 0.65 F E 0.72 E E 0.83 V E 0.88 E E 0.84 N E 0.81 H E 0.63 T C 0.58 K C 0.83 E C 0.84 S E 0.63 I E 0.87 T E 0.91 F E 0.91 L E 0.89 L E 0.82 K E 0.57 D C 0.70 N C 0.89 E H 0.71 E H 0.76 T H 0.78 R H 0.69 K H 0.49 V C 0.60 Y C 0.78 P C 0.81 F C 0.73 K C 0.53 F E 0.83 E E 0.90 F E 0.92 R E 0.93 V E 0.93 N E 0.93 Y E 0.92 N E 0.92 L E 0.89 M E 0.61 N C 0.89 N C 0.90 L E 0.58 L E 0.90 E E 0.93 E E 0.93 N E 0.93 F E 0.93 S E 0.92 V E 0.91 V E 0.85 N E 0.55 K C 0.81 S C 0.89 D C 0.87 E C 0.83 T C 0.69 M C 0.71 I C 0.57 F E 0.59 G E 0.64 V E 0.60 G E 0.47 G C 0.55 H C 0.71 P C 0.64 G C 0.51 F E 0.47 N E 0.56 L C 0.60 P C 0.68 T C 0.75 D C 0.69 H C 0.67 G C 0.66 E C 0.50 N E 0.55 K E 0.48 E C 0.41 D C 0.50 F C 0.47 Y C 0.40 F C 0.38 D C 0.43 M C 0.50 H C 0.54 P C 0.47 S C 0.49 V C 0.53 T C 0.57 R C 0.59 V C 0.56 R C 0.54 I C 0.56 P C 0.58 L C 0.63 K C 0.69 D C 0.68 A C 0.68 S C 0.68 L C 0.66 D C 0.63 W C 0.64 N C 0.66 N C 0.62 R C 0.62 S C 0.64 L C 0.63 A C 0.62 P C 0.62 T C 0.62 D C 0.63 S C 0.60 L C 0.57 I C 0.53 A C 0.54 L C 0.57 S C 0.59 D C 0.59 D C 0.53 L C 0.53 F C 0.60 K C 0.59 D C 0.51 D H 0.50 A H 0.59 L H 0.57 I H 0.55 Y H 0.53 E H 0.49 L C 0.37 R C 0.59 G C 0.76 N C 0.79 D C 0.82 N C 0.74 K C 0.49 V E 0.77 S E 0.88 L E 0.89 R E 0.86 T E 0.71 D C 0.71 K C 0.85 N C 0.87 K C 0.84 F C 0.54 H E 0.84 V E 0.91 N E 0.92 V E 0.91 W E 0.84 T E 0.52 R C 0.81 D C 0.87 A C 0.79 P C 0.76 F E 0.51 V E 0.85 G E 0.91 I E 0.92 W E 0.87 S E 0.62 Q C 0.66 Y C 0.80 P C 0.82 K C 0.81 T C 0.85 D C 0.86 N C 0.79 Y E 0.57 V E 0.76 C E 0.78 I E 0.70 E C 0.52 P C 0.71 W C 0.77 W C 0.81 G C 0.82 I C 0.79 A C 0.69 D C 0.68 R C 0.61 D C 0.56 D C 0.61 A C 0.61 D C 0.57 G H 0.48 D H 0.58 L H 0.58 E H 0.50 H C 0.51 K C 0.69 Y C 0.73 G C 0.73 M C 0.52 N E 0.76 H E 0.80 L E 0.59 K C 0.81 P C 0.91 G C 0.92 K C 0.69 E E 0.77 F E 0.86 Q E 0.88 A E 0.89 G E 0.91 F E 0.92 S E 0.93 M E 0.92 T E 0.91 Y E 0.87 H E 0.58 S C 0.65 T C 0.81 T C 0.75 D C 0.72 E C 0.68 V C 0.64 K C 0.66 L C 0.62 E C 0.66 H C 0.81 H C 0.66 H C 0.65 H C 0.67 H C 0.78 H C 0.91 END