PFRMAT SS TARGET T0448 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0448.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0448.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0448.t04.str2.rdb (weight 1.54758) METHOD T0448.t04.alpha.rdb (weight 0.659012) METHOD T0448.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0448.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0448.t2k.str2.rdb (weight 1.54758) METHOD T0448.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0448.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2322 METHOD METHOD ============================================ METHOD Comments from T0448.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2322 METHOD METHOD ============================================ METHOD Comments from T0448.t04.str2.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2322 METHOD METHOD ============================================ METHOD Comments from T0448.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2322 METHOD METHOD ============================================ METHOD Comments from T0448.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 124 METHOD METHOD ============================================ METHOD Comments from T0448.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 124 METHOD METHOD ============================================ METHOD Comments from T0448.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 124 METHOD METHOD ============================================ METHOD Comments from T0448.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0448 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0448.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 124 METHOD METHOD ============================================ MODEL 1 M C 0.85 I C 0.59 A C 0.51 M C 0.44 I C 0.36 V H 0.37 K H 0.41 G H 0.42 G H 0.54 L H 0.62 A H 0.65 M H 0.69 A H 0.66 I H 0.61 S H 0.54 N C 0.53 G C 0.64 H C 0.67 V C 0.75 S C 0.80 F C 0.81 K C 0.60 R E 0.79 P E 0.91 A E 0.92 W E 0.91 L E 0.78 G C 0.52 D C 0.73 S C 0.65 I C 0.52 T C 0.54 A C 0.62 N C 0.72 N C 0.75 G C 0.78 L C 0.76 A C 0.77 T C 0.76 V C 0.76 H C 0.70 Y C 0.65 H H 0.66 D H 0.88 I H 0.91 L H 0.92 A H 0.91 A H 0.89 D H 0.82 W H 0.68 D C 0.63 V C 0.86 E C 0.62 R E 0.70 S E 0.87 D E 0.86 N E 0.81 L E 0.60 G E 0.47 I C 0.63 S C 0.72 G C 0.65 S C 0.50 T H 0.49 I H 0.68 G H 0.68 S H 0.68 R H 0.69 Y H 0.71 D H 0.70 A H 0.69 M H 0.66 A H 0.64 V H 0.56 R H 0.60 Y H 0.64 Q H 0.65 A H 0.63 I H 0.58 P C 0.55 E C 0.72 D C 0.84 A C 0.88 D C 0.82 F E 0.92 I E 0.93 A E 0.93 V E 0.93 F E 0.85 G E 0.50 G C 0.65 V C 0.62 N C 0.59 D C 0.54 Y C 0.56 G C 0.60 R C 0.66 D C 0.72 Q C 0.73 P C 0.70 L C 0.66 G C 0.73 Q C 0.73 Y C 0.73 G C 0.80 D C 0.82 C C 0.76 D C 0.84 M H 0.88 T H 0.89 T H 0.92 F H 0.92 Y H 0.95 G H 0.95 A H 0.95 L H 0.96 M H 0.96 M H 0.96 L H 0.96 L H 0.96 T H 0.96 G H 0.94 L H 0.92 Q H 0.87 T H 0.72 N C 0.57 W C 0.86 P C 0.88 T C 0.77 V E 0.53 P E 0.84 K E 0.92 L E 0.91 F E 0.89 I E 0.77 S C 0.52 A C 0.69 I C 0.72 H C 0.73 I C 0.75 G C 0.71 S C 0.56 D C 0.54 F C 0.57 G C 0.67 G C 0.71 S C 0.67 F C 0.64 S C 0.60 A C 0.54 V H 0.48 T H 0.53 N H 0.55 G H 0.58 L H 0.63 G H 0.69 Y H 0.78 R H 0.82 Q H 0.89 S H 0.91 D H 0.92 Y H 0.94 E H 0.95 A H 0.95 A H 0.96 I H 0.96 A H 0.96 Q H 0.96 M H 0.95 T H 0.94 A H 0.90 D H 0.80 Y C 0.60 G C 0.93 V C 0.90 P C 0.70 H E 0.70 L E 0.74 S E 0.59 L C 0.46 Y C 0.47 R H 0.55 D H 0.59 A H 0.51 G C 0.48 M C 0.48 T C 0.56 F C 0.51 A C 0.55 I C 0.56 P H 0.51 A H 0.49 Q H 0.51 A H 0.62 A H 0.61 I H 0.54 Y C 0.56 S C 0.73 V C 0.77 D C 0.82 T C 0.82 L C 0.74 H C 0.79 P C 0.84 N C 0.86 N H 0.87 A H 0.92 G H 0.93 H H 0.95 R H 0.96 V H 0.96 I H 0.95 A H 0.96 R H 0.95 K H 0.95 L H 0.95 Q H 0.95 S H 0.95 F H 0.94 L H 0.93 D H 0.89 S H 0.79 H H 0.65 F H 0.48 L C 0.52 E C 0.59 H C 0.65 H C 0.69 H C 0.72 H C 0.74 H C 0.81 H C 0.91 END