PFRMAT SS TARGET T0438 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0438.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0438.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0438.t04.str2.rdb (weight 1.54758) METHOD T0438.t04.alpha.rdb (weight 0.659012) METHOD T0438.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0438.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0438.t2k.str2.rdb (weight 1.54758) METHOD T0438.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0438.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1045.57 METHOD METHOD ============================================ METHOD Comments from T0438.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1045.57 METHOD METHOD ============================================ METHOD Comments from T0438.t04.str2.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1045.57 METHOD METHOD ============================================ METHOD Comments from T0438.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1045.57 METHOD METHOD ============================================ METHOD Comments from T0438.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 576 METHOD METHOD ============================================ METHOD Comments from T0438.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 576 METHOD METHOD ============================================ METHOD Comments from T0438.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 576 METHOD METHOD ============================================ METHOD Comments from T0438.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0438 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0438.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 576 METHOD METHOD ============================================ MODEL 1 M C 0.72 Q H 0.49 W H 0.51 Q C 0.48 E H 0.56 L H 0.78 Y H 0.82 R H 0.83 Q H 0.78 R H 0.64 V H 0.51 C C 0.62 S C 0.71 A C 0.84 D H 0.94 E H 0.95 A H 0.95 V H 0.95 V H 0.91 D H 0.78 S H 0.65 L C 0.64 K C 0.84 P C 0.88 G C 0.91 T C 0.60 K E 0.84 V E 0.89 V E 0.87 F E 0.75 G C 0.48 H C 0.66 A C 0.70 A C 0.75 A C 0.80 A C 0.76 P C 0.49 V H 0.72 R H 0.77 F H 0.83 S H 0.91 Q H 0.94 A H 0.95 M H 0.95 Y H 0.95 R H 0.93 Q H 0.91 R H 0.89 E H 0.84 K H 0.73 L C 0.49 E C 0.67 N C 0.65 I C 0.61 T C 0.53 V E 0.48 F E 0.62 H E 0.62 M E 0.55 L E 0.40 Y C 0.54 F C 0.72 G C 0.78 D C 0.54 A H 0.52 P H 0.59 H H 0.55 L H 0.49 A C 0.52 P H 0.51 E H 0.48 M C 0.53 R C 0.66 S C 0.62 H C 0.45 V E 0.62 H E 0.68 P E 0.64 T C 0.50 L C 0.55 N C 0.61 F C 0.64 L C 0.76 E C 0.80 G H 0.75 N H 0.84 S H 0.90 R H 0.91 P H 0.90 A H 0.87 S H 0.82 R H 0.73 D C 0.51 R C 0.73 R C 0.66 V C 0.62 D C 0.65 F C 0.58 I C 0.62 P C 0.56 C C 0.47 H C 0.46 F C 0.43 H C 0.47 E C 0.49 V H 0.51 P H 0.85 E H 0.90 L H 0.92 F H 0.91 R H 0.89 Q H 0.59 G C 0.79 F C 0.88 F C 0.86 P C 0.87 L C 0.82 D C 0.67 V E 0.92 A E 0.93 V E 0.93 V E 0.90 Q E 0.69 V C 0.61 S C 0.78 T C 0.81 P C 0.71 N C 0.83 E C 0.83 E C 0.88 G C 0.84 Y C 0.65 C E 0.71 S E 0.62 F E 0.48 G C 0.61 V C 0.64 S C 0.70 C C 0.67 D C 0.74 Y C 0.66 T C 0.63 K H 0.93 A H 0.94 A H 0.94 A H 0.93 E H 0.84 C H 0.50 A C 0.82 P C 0.84 V E 0.71 V E 0.91 V E 0.92 A E 0.92 E E 0.85 V E 0.54 N C 0.80 K C 0.85 Q C 0.87 M C 0.84 P C 0.80 F C 0.69 I C 0.69 G C 0.77 G C 0.81 E C 0.78 N C 0.77 L C 0.75 I C 0.74 H C 0.84 I H 0.71 S H 0.67 K H 0.58 L E 0.52 T E 0.72 H E 0.90 I E 0.92 I E 0.91 E E 0.78 V C 0.66 D C 0.86 E C 0.87 P C 0.82 I C 0.78 A C 0.73 E C 0.75 V C 0.82 L C 0.82 P C 0.81 P C 0.87 A C 0.90 G C 0.88 S C 0.89 D H 0.91 L H 0.94 E H 0.95 L H 0.96 R H 0.96 I H 0.95 G H 0.96 Q H 0.96 N H 0.95 C H 0.94 A H 0.93 S H 0.85 L H 0.75 I C 0.56 K C 0.76 D C 0.88 G C 0.87 D C 0.65 T E 0.58 L E 0.71 Q E 0.73 L E 0.55 G C 0.50 I C 0.59 G C 0.66 G C 0.59 I H 0.65 P H 0.84 D H 0.91 A H 0.93 V H 0.92 L H 0.88 R H 0.79 A H 0.64 L C 0.71 E C 0.79 G C 0.77 H C 0.76 K C 0.69 D E 0.53 L E 0.80 G E 0.86 I E 0.86 H E 0.79 T E 0.56 E C 0.43 M C 0.44 F H 0.39 T H 0.52 D H 0.59 G H 0.66 V H 0.72 M H 0.74 R H 0.73 M H 0.74 I H 0.72 R H 0.69 K C 0.60 G C 0.87 I C 0.71 I C 0.50 N C 0.71 G C 0.48 K H 0.48 K H 0.49 K C 0.39 T C 0.45 L C 0.56 H C 0.70 P C 0.76 E C 0.70 K E 0.50 V E 0.78 V E 0.83 T E 0.81 S E 0.65 L C 0.53 I C 0.63 F C 0.67 G C 0.70 S C 0.62 K H 0.91 E H 0.93 L H 0.94 Y H 0.94 D H 0.93 F H 0.90 V H 0.85 N H 0.66 N C 0.57 N C 0.83 P C 0.67 V C 0.58 I C 0.47 E C 0.45 C C 0.54 Y C 0.72 P C 0.76 V C 0.61 D C 0.57 Y C 0.56 I C 0.67 N C 0.78 N C 0.82 P H 0.83 D H 0.89 V H 0.90 I H 0.89 G H 0.79 K H 0.52 N C 0.76 D C 0.76 R C 0.65 M E 0.42 V E 0.77 S E 0.84 I E 0.81 N E 0.61 S E 0.57 C E 0.61 L E 0.74 E E 0.76 M E 0.72 D E 0.50 L H 0.41 M C 0.60 G C 0.61 Q C 0.46 A E 0.50 A E 0.42 S C 0.43 E C 0.51 S C 0.63 I C 0.71 G C 0.83 Y C 0.77 E C 0.49 Q E 0.65 F E 0.56 S C 0.64 G C 0.80 S C 0.67 G C 0.66 G C 0.55 Q H 0.68 V H 0.80 D H 0.82 F H 0.79 L H 0.73 R H 0.49 G C 0.63 A C 0.60 K C 0.46 R C 0.51 S C 0.81 K C 0.86 G C 0.92 G C 0.81 I E 0.50 S E 0.86 I E 0.91 M E 0.90 A E 0.85 F E 0.69 P E 0.53 S C 0.49 T C 0.51 A C 0.72 K C 0.82 K C 0.91 G C 0.90 T C 0.80 E C 0.65 S C 0.64 R C 0.54 I C 0.60 V C 0.70 P C 0.57 I C 0.43 L C 0.53 K C 0.64 E C 0.71 G C 0.69 A C 0.72 C C 0.71 V C 0.66 T C 0.67 T C 0.76 G C 0.76 R C 0.64 N C 0.62 E C 0.49 V E 0.52 D E 0.60 Y E 0.86 V E 0.90 V E 0.87 T E 0.71 E C 0.51 Y C 0.55 G C 0.45 V E 0.54 A E 0.58 R E 0.59 L C 0.53 R C 0.81 G C 0.90 A C 0.89 T C 0.90 L H 0.91 R H 0.94 Q H 0.95 R H 0.96 A H 0.96 E H 0.95 A H 0.95 L H 0.95 T H 0.93 A H 0.87 I H 0.69 A C 0.70 H C 0.85 P H 0.74 D H 0.76 F H 0.78 R H 0.93 P H 0.95 A H 0.95 L H 0.95 E H 0.96 E H 0.95 E H 0.95 I H 0.93 R H 0.90 R H 0.85 R H 0.58 F C 0.67 E C 0.70 L C 0.72 E C 0.78 H C 0.76 H C 0.78 H C 0.72 H C 0.68 H C 0.81 H C 0.92 END