PFRMAT SS TARGET T0427 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0427.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0427.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0427.t04.str2.rdb (weight 1.54758) METHOD T0427.t04.alpha.rdb (weight 0.659012) METHOD T0427.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0427.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0427.t2k.str2.rdb (weight 1.54758) METHOD T0427.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0427.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2513 METHOD METHOD ============================================ METHOD Comments from T0427.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2513 METHOD METHOD ============================================ METHOD Comments from T0427.t04.str2.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2513 METHOD METHOD ============================================ METHOD Comments from T0427.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2513 METHOD METHOD ============================================ METHOD Comments from T0427.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 856 METHOD METHOD ============================================ METHOD Comments from T0427.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 856 METHOD METHOD ============================================ METHOD Comments from T0427.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 856 METHOD METHOD ============================================ METHOD Comments from T0427.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0427 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0427.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 856 METHOD METHOD ============================================ MODEL 1 M C 0.85 S C 0.50 V E 0.76 Q E 0.82 L C 0.51 V C 0.80 K C 0.91 G C 0.81 V E 0.68 N E 0.91 L E 0.93 H E 0.92 V E 0.91 I E 0.85 P E 0.69 T C 0.75 E C 0.86 K C 0.89 Y C 0.82 K C 0.70 T E 0.77 V E 0.90 R E 0.92 L E 0.93 L E 0.93 V E 0.92 R E 0.91 F E 0.84 N E 0.61 T C 0.66 R C 0.84 L C 0.78 N C 0.70 H C 0.72 E C 0.77 T C 0.49 I H 0.58 T H 0.61 K H 0.80 R H 0.82 T H 0.82 L H 0.79 L H 0.80 S H 0.86 S H 0.88 L H 0.86 M H 0.78 E H 0.61 T C 0.58 N C 0.69 S C 0.63 L C 0.57 N C 0.50 Y H 0.54 P H 0.56 N H 0.84 Q H 0.93 V H 0.95 K H 0.95 L H 0.96 S H 0.95 E H 0.95 R H 0.93 L H 0.88 A H 0.75 E C 0.52 L C 0.74 Y C 0.78 G C 0.75 A C 0.77 S C 0.82 F C 0.85 G H 0.91 I H 0.94 G H 0.95 V H 0.96 S H 0.95 K H 0.95 K H 0.94 G H 0.93 N H 0.90 Q H 0.78 H H 0.49 W C 0.75 F C 0.56 N E 0.67 I E 0.73 S E 0.71 M E 0.61 N E 0.52 I C 0.49 V C 0.64 N C 0.72 D C 0.66 H C 0.46 Y E 0.72 L E 0.81 Q E 0.81 D E 0.77 S E 0.57 Q E 0.47 V C 0.52 L C 0.65 A H 0.66 E H 0.70 A H 0.68 V H 0.87 D H 0.93 F H 0.94 L H 0.95 K H 0.95 E H 0.93 I H 0.92 I H 0.90 F H 0.89 A H 0.90 P H 0.88 N H 0.86 I H 0.76 Q H 0.57 A C 0.77 G C 0.78 Q C 0.77 F C 0.86 E C 0.91 A H 0.90 E H 0.92 T H 0.94 F H 0.95 Q H 0.95 R H 0.95 E H 0.95 K H 0.95 E H 0.95 N H 0.96 L H 0.96 K H 0.96 A H 0.96 Y H 0.95 L H 0.95 E H 0.93 S H 0.87 I H 0.78 V H 0.62 E C 0.64 D C 0.86 K H 0.74 Q H 0.84 T H 0.91 Y H 0.93 A H 0.92 S H 0.93 L H 0.94 A H 0.94 L H 0.94 Q H 0.93 S H 0.90 V H 0.83 Y H 0.61 F C 0.73 N C 0.82 Q C 0.83 S C 0.86 E C 0.84 D C 0.77 Q C 0.75 K C 0.75 I C 0.75 P C 0.78 S C 0.74 F C 0.79 G C 0.86 T C 0.83 V H 0.86 A H 0.87 A H 0.84 L H 0.83 A H 0.68 E C 0.60 E C 0.79 T C 0.88 A H 0.93 A H 0.94 S H 0.95 L H 0.96 A H 0.96 A H 0.95 Y H 0.95 Y H 0.94 Q H 0.91 K H 0.84 M H 0.70 L C 0.60 A C 0.81 E C 0.78 D C 0.85 Q C 0.72 V E 0.74 D E 0.91 I E 0.93 F E 0.93 V E 0.92 L E 0.73 G C 0.61 D C 0.77 V C 0.76 N C 0.89 E H 0.89 A H 0.94 E H 0.95 L H 0.95 V H 0.96 P H 0.96 L H 0.96 F H 0.95 K H 0.95 Q H 0.92 L H 0.86 P H 0.68 F C 0.60 T C 0.67 P C 0.77 R C 0.79 E C 0.73 E C 0.76 G C 0.77 K C 0.78 A C 0.79 A C 0.80 I C 0.80 F C 0.79 Y C 0.80 N C 0.80 Q C 0.80 P C 0.82 I C 0.80 R C 0.76 N C 0.76 V C 0.75 I C 0.68 E E 0.50 E E 0.76 R E 0.84 T E 0.83 E E 0.73 R C 0.51 E C 0.76 V C 0.81 L C 0.68 A C 0.59 Q C 0.46 S E 0.42 K E 0.65 L E 0.80 N E 0.80 L E 0.77 A E 0.65 Y E 0.46 N C 0.60 T C 0.75 D C 0.80 I C 0.82 Y C 0.80 Y C 0.78 G C 0.84 D C 0.81 S H 0.53 Y H 0.56 Y H 0.77 F H 0.86 A H 0.94 L H 0.95 Q H 0.96 V H 0.96 F H 0.96 N H 0.95 G H 0.92 I H 0.87 F H 0.59 G C 0.76 G C 0.83 F C 0.75 P C 0.50 H H 0.61 S H 0.82 K H 0.93 L H 0.93 F H 0.94 M H 0.94 N H 0.94 V H 0.94 R H 0.93 E H 0.90 K H 0.81 E C 0.53 H C 0.84 L C 0.65 A E 0.55 Y E 0.65 Y E 0.72 A E 0.69 S E 0.68 S E 0.59 S E 0.52 I E 0.45 D C 0.57 T C 0.69 F C 0.74 R C 0.76 G C 0.66 F E 0.65 M E 0.86 T E 0.91 V E 0.91 Q E 0.87 T E 0.76 G E 0.52 I C 0.72 D C 0.86 G C 0.52 K C 0.50 N H 0.57 R H 0.91 N H 0.95 Q H 0.95 V H 0.96 L H 0.96 R H 0.96 L H 0.96 I H 0.96 S H 0.96 T H 0.96 E H 0.96 L H 0.96 E H 0.96 N H 0.95 I H 0.94 R H 0.92 L H 0.69 G C 0.72 K C 0.92 I C 0.92 R C 0.94 E H 0.93 L H 0.94 E H 0.95 I H 0.96 E H 0.96 Q H 0.96 T H 0.96 K H 0.96 A H 0.95 M H 0.95 L H 0.94 K H 0.92 N H 0.85 Q H 0.76 Y H 0.75 I H 0.72 L H 0.66 A H 0.52 L C 0.54 D C 0.68 N C 0.79 A H 0.80 G H 0.89 A H 0.93 W H 0.95 L H 0.95 E H 0.95 K H 0.95 E H 0.95 Y H 0.94 L H 0.94 N H 0.93 E H 0.92 L H 0.85 M H 0.64 P C 0.73 Q C 0.88 T C 0.85 M C 0.72 L C 0.72 T C 0.71 A H 0.91 E H 0.93 E H 0.93 W H 0.94 I H 0.95 A H 0.94 R H 0.92 I H 0.86 N H 0.74 A C 0.52 V C 0.78 T C 0.90 I H 0.93 P H 0.94 E H 0.95 I H 0.96 Q H 0.96 E H 0.96 V H 0.95 A H 0.94 K H 0.92 R H 0.87 L H 0.79 E C 0.49 L C 0.74 Q C 0.79 A C 0.83 I C 0.78 F E 0.74 F E 0.91 L E 0.93 E E 0.92 G E 0.89 E E 0.64 T C 0.70 E C 0.83 N C 0.86 D C 0.92 END