PFRMAT SS TARGET T0413 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0413.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0413.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0413.t04.str2.rdb (weight 1.54758) METHOD T0413.t04.alpha.rdb (weight 0.659012) METHOD T0413.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0413.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0413.t2k.str2.rdb (weight 1.54758) METHOD T0413.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0413.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2021 METHOD METHOD ============================================ METHOD Comments from T0413.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2021 METHOD METHOD ============================================ METHOD Comments from T0413.t04.str2.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2021 METHOD METHOD ============================================ METHOD Comments from T0413.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 2021 METHOD METHOD ============================================ METHOD Comments from T0413.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 320 METHOD METHOD ============================================ METHOD Comments from T0413.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 320 METHOD METHOD ============================================ METHOD Comments from T0413.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 320 METHOD METHOD ============================================ METHOD Comments from T0413.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0413 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0413.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 320 METHOD METHOD ============================================ MODEL 1 S C 0.61 N H 0.51 A H 0.74 M H 0.84 K H 0.86 P H 0.90 A H 0.90 D H 0.90 L H 0.90 T H 0.89 N H 0.87 A H 0.82 D H 0.75 R H 0.69 I H 0.68 A H 0.68 L H 0.62 E H 0.60 L H 0.51 G C 0.52 H C 0.60 A C 0.68 G C 0.70 R C 0.69 N C 0.69 A C 0.55 I E 0.64 P E 0.72 Y E 0.72 L E 0.66 D E 0.51 D C 0.58 D C 0.71 R C 0.80 N C 0.83 A C 0.83 D C 0.75 R C 0.60 P E 0.62 F E 0.82 T E 0.88 L E 0.89 N E 0.88 T E 0.81 Y E 0.65 R C 0.60 P C 0.78 Y C 0.79 G C 0.82 Y C 0.81 T C 0.83 P C 0.86 D C 0.87 R C 0.82 P C 0.62 V E 0.91 V E 0.93 V E 0.93 V E 0.93 Q E 0.85 H C 0.53 G C 0.79 V C 0.78 L C 0.78 R C 0.80 N C 0.80 G H 0.72 A H 0.77 D H 0.78 Y H 0.78 R H 0.77 D H 0.74 F H 0.74 W H 0.82 I H 0.90 P H 0.92 A H 0.94 A H 0.93 D H 0.90 R H 0.77 H C 0.71 K C 0.93 L C 0.62 L E 0.87 I E 0.92 V E 0.91 A E 0.83 P E 0.51 T C 0.76 F C 0.78 S C 0.76 D C 0.77 E C 0.76 I C 0.72 W C 0.70 P C 0.66 G C 0.63 V C 0.58 E C 0.55 S C 0.54 Y C 0.57 N C 0.63 N C 0.62 G C 0.65 R C 0.63 A C 0.57 F C 0.57 T C 0.61 A C 0.61 A C 0.60 G C 0.62 N C 0.65 P C 0.67 R C 0.71 H C 0.72 V C 0.72 D C 0.72 G C 0.54 W C 0.52 T H 0.59 Y H 0.90 A H 0.92 L H 0.94 V H 0.95 A H 0.96 R H 0.96 V H 0.96 L H 0.96 A H 0.95 N H 0.95 I H 0.94 R H 0.90 A H 0.78 A H 0.58 E C 0.69 I C 0.85 A C 0.86 D C 0.87 C C 0.54 E C 0.60 Q C 0.45 V E 0.78 Y E 0.88 L E 0.91 F E 0.84 G E 0.66 H C 0.58 S C 0.73 A H 0.68 G H 0.86 G H 0.95 Q H 0.96 F H 0.96 V H 0.96 H H 0.96 R H 0.96 L H 0.95 M H 0.93 S H 0.82 S H 0.61 Q C 0.80 P C 0.65 H C 0.63 A C 0.51 P C 0.40 F E 0.57 H E 0.73 A E 0.81 V E 0.83 T E 0.81 A E 0.65 A C 0.55 N C 0.71 P C 0.70 G C 0.66 W C 0.61 Y C 0.60 T C 0.59 L C 0.64 P C 0.69 T C 0.70 F C 0.59 E C 0.57 H C 0.59 R C 0.59 F C 0.61 P C 0.56 E C 0.50 G C 0.50 L C 0.49 D C 0.52 G C 0.57 V C 0.55 G H 0.48 L H 0.54 T H 0.53 E H 0.57 D H 0.57 H H 0.55 L H 0.57 A H 0.51 R C 0.54 L C 0.67 L C 0.78 A C 0.85 Y C 0.85 P C 0.58 M E 0.90 T E 0.93 I E 0.92 L E 0.90 A E 0.61 G C 0.69 D C 0.74 Q C 0.73 D C 0.76 I C 0.75 A C 0.76 T C 0.80 D C 0.81 D C 0.49 P H 0.59 N H 0.61 L H 0.65 P H 0.77 S H 0.77 E H 0.80 P H 0.89 A H 0.91 A H 0.92 L H 0.90 R H 0.83 Q H 0.61 G C 0.62 P C 0.64 H C 0.60 R H 0.51 Y H 0.60 A H 0.58 R H 0.54 A H 0.63 R H 0.80 H H 0.87 Y H 0.91 Y H 0.93 E H 0.94 A H 0.94 G H 0.94 Q H 0.93 R H 0.91 A H 0.88 A H 0.80 A H 0.69 Q H 0.49 R C 0.71 G C 0.84 L C 0.86 P C 0.85 F C 0.65 G E 0.58 W E 0.84 Q E 0.89 L E 0.91 Q E 0.88 V E 0.86 V E 0.61 P C 0.77 G C 0.88 I C 0.79 G C 0.79 H C 0.76 D C 0.75 G C 0.53 Q H 0.58 A H 0.69 M H 0.73 S H 0.76 Q H 0.80 V H 0.83 C H 0.91 A H 0.93 S H 0.92 L H 0.92 W H 0.90 F H 0.86 D H 0.75 G C 0.48 R C 0.81 M C 0.85 P C 0.82 D C 0.78 A C 0.65 A C 0.65 E C 0.65 L C 0.71 A C 0.71 R C 0.68 L C 0.66 A C 0.68 G C 0.71 S C 0.77 Q C 0.81 S C 0.86 A C 0.91 END