PFRMAT SS TARGET T0412 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0412.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0412.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0412.t04.str2.rdb (weight 1.54758) METHOD T0412.t04.alpha.rdb (weight 0.659012) METHOD T0412.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0412.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0412.t2k.str2.rdb (weight 1.54758) METHOD T0412.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0412.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1764 METHOD METHOD ============================================ METHOD Comments from T0412.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1764 METHOD METHOD ============================================ METHOD Comments from T0412.t04.str2.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1764 METHOD METHOD ============================================ METHOD Comments from T0412.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1764 METHOD METHOD ============================================ METHOD Comments from T0412.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 365 METHOD METHOD ============================================ METHOD Comments from T0412.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 365 METHOD METHOD ============================================ METHOD Comments from T0412.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 365 METHOD METHOD ============================================ METHOD Comments from T0412.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0412 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0412.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 365 METHOD METHOD ============================================ MODEL 1 S C 0.80 N C 0.69 A C 0.73 L C 0.76 F C 0.73 S H 0.81 S H 0.87 R H 0.89 D H 0.88 I H 0.85 L H 0.89 E H 0.94 V H 0.95 L H 0.96 Q H 0.96 D H 0.96 I H 0.96 H H 0.95 M H 0.91 E H 0.83 T C 0.48 G C 0.92 E C 0.83 T E 0.57 V E 0.80 A E 0.88 I E 0.88 A E 0.88 T E 0.87 K E 0.72 N C 0.67 D C 0.87 I C 0.78 Y E 0.79 L E 0.92 Q E 0.93 Y E 0.93 I E 0.92 Q E 0.89 I E 0.83 I E 0.75 E E 0.56 S C 0.67 V C 0.75 H C 0.75 A C 0.53 L E 0.68 R E 0.80 F E 0.79 H E 0.73 V E 0.56 D C 0.67 E C 0.81 N C 0.88 A C 0.72 I E 0.52 R E 0.50 P C 0.52 L C 0.47 T C 0.45 M C 0.47 S C 0.52 S H 0.56 N H 0.69 G H 0.71 W H 0.78 M H 0.78 L H 0.79 M H 0.74 S H 0.53 T C 0.70 M C 0.90 N C 0.92 D H 0.89 K H 0.93 A H 0.95 I H 0.95 D H 0.95 N H 0.95 T H 0.94 V H 0.92 R H 0.81 R H 0.62 A C 0.63 N C 0.78 T C 0.73 I C 0.70 T C 0.68 Q C 0.75 K C 0.85 D C 0.72 G C 0.77 I C 0.74 R C 0.74 F C 0.77 E C 0.84 V H 0.94 D H 0.95 D H 0.95 M H 0.96 M H 0.96 A H 0.95 R H 0.95 I H 0.96 R H 0.95 Q H 0.95 V H 0.94 R H 0.93 E H 0.86 Q H 0.50 G C 0.84 Y C 0.74 A C 0.50 S C 0.48 A C 0.60 E C 0.53 H C 0.54 I C 0.49 P C 0.59 F C 0.67 V C 0.73 G C 0.78 G E 0.54 G E 0.78 T E 0.89 I E 0.90 C E 0.89 V E 0.85 L E 0.83 L E 0.72 P E 0.66 M C 0.74 T C 0.85 I C 0.91 Q C 0.91 G C 0.72 Q E 0.77 P E 0.87 V E 0.92 T E 0.92 M E 0.92 G E 0.91 L E 0.82 G E 0.61 G C 0.64 A C 0.65 L C 0.52 D C 0.52 R C 0.61 I C 0.79 K C 0.86 Q H 0.83 N H 0.84 Y H 0.88 D H 0.90 R H 0.89 Y H 0.87 L H 0.89 E H 0.94 L H 0.95 L H 0.95 L H 0.96 N H 0.95 G H 0.95 V H 0.95 Q H 0.95 Q H 0.94 L H 0.94 K H 0.93 K H 0.91 S H 0.86 D H 0.76 S C 0.54 F C 0.86 H C 0.83 Q C 0.80 P C 0.83 I C 0.91 END