PFRMAT SS TARGET T0404 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0404.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0404.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0404.t04.str2.rdb (weight 1.54758) METHOD T0404.t04.alpha.rdb (weight 0.659012) METHOD T0404.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0404.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0404.t2k.str2.rdb (weight 1.54758) METHOD T0404.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0404.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 82.5734 METHOD METHOD ============================================ METHOD Comments from T0404.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 82.5734 METHOD METHOD ============================================ METHOD Comments from T0404.t04.str2.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 82.5734 METHOD METHOD ============================================ METHOD Comments from T0404.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 82.5734 METHOD METHOD ============================================ METHOD Comments from T0404.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ METHOD Comments from T0404.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ METHOD Comments from T0404.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ METHOD Comments from T0404.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0404 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0404.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 47 METHOD METHOD ============================================ MODEL 1 M C 0.90 S C 0.78 K C 0.71 R C 0.59 A C 0.52 N E 0.55 K E 0.75 L E 0.82 V E 0.85 I E 0.87 V E 0.82 T E 0.53 E C 0.61 K H 0.61 V H 0.73 L H 0.74 L H 0.85 K H 0.85 K H 0.92 V H 0.95 A H 0.96 K H 0.96 I H 0.96 I H 0.96 E H 0.95 E H 0.92 A C 0.53 G C 0.93 A C 0.89 T C 0.81 G E 0.55 Y E 0.82 T E 0.89 V E 0.86 V E 0.70 D C 0.53 T C 0.65 G C 0.79 G C 0.80 K C 0.70 G C 0.74 S C 0.75 R C 0.78 N C 0.76 V C 0.56 R C 0.48 S C 0.61 T C 0.75 G C 0.76 K C 0.67 P C 0.61 N C 0.59 T C 0.60 S C 0.56 D C 0.49 T C 0.47 D C 0.42 S C 0.45 N C 0.49 V C 0.48 K E 0.67 F E 0.83 E E 0.89 V E 0.92 L E 0.90 T E 0.85 E E 0.62 N C 0.81 R H 0.61 E H 0.86 M H 0.89 A H 0.90 E H 0.92 K H 0.91 I H 0.92 A H 0.93 D H 0.92 Q H 0.90 V H 0.86 A H 0.81 I H 0.75 K H 0.74 F H 0.67 F H 0.50 T C 0.54 D C 0.77 Y C 0.75 A C 0.50 G E 0.85 I E 0.92 I E 0.92 Y E 0.92 I E 0.82 C E 0.59 E C 0.53 A E 0.57 E E 0.74 V E 0.80 L E 0.68 Y C 0.55 G C 0.58 R C 0.58 T C 0.45 F C 0.55 C C 0.67 G C 0.84 P C 0.84 D C 0.87 G C 0.88 C C 0.90 END