PFRMAT SS TARGET T0403 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0403.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0403.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0403.t04.str2.rdb (weight 1.54758) METHOD T0403.t04.alpha.rdb (weight 0.659012) METHOD T0403.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0403.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0403.t2k.str2.rdb (weight 1.54758) METHOD T0403.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0403.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1046 METHOD METHOD ============================================ METHOD Comments from T0403.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1046 METHOD METHOD ============================================ METHOD Comments from T0403.t04.str2.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1046 METHOD METHOD ============================================ METHOD Comments from T0403.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1046 METHOD METHOD ============================================ METHOD Comments from T0403.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1006 METHOD METHOD ============================================ METHOD Comments from T0403.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1006 METHOD METHOD ============================================ METHOD Comments from T0403.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1006 METHOD METHOD ============================================ METHOD Comments from T0403.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0403 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0403.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1006 METHOD METHOD ============================================ MODEL 1 M C 0.73 G C 0.60 R C 0.57 D C 0.59 L C 0.57 Q E 0.57 V E 0.78 T E 0.88 L E 0.91 Y E 0.85 G E 0.84 T E 0.89 I E 0.87 K E 0.80 A E 0.71 G E 0.73 V E 0.82 E E 0.82 V E 0.79 S E 0.70 R C 0.50 V C 0.68 K C 0.71 D C 0.74 A C 0.76 G C 0.76 T C 0.77 Y C 0.76 K C 0.72 A C 0.68 Q C 0.73 G C 0.76 G C 0.67 K C 0.50 S E 0.64 K E 0.73 T E 0.72 A E 0.64 T E 0.51 Q C 0.53 I C 0.64 A C 0.67 D C 0.69 F C 0.70 G C 0.67 S C 0.58 K E 0.49 I E 0.50 G E 0.50 F E 0.68 K E 0.66 G E 0.67 Q E 0.67 E E 0.65 D E 0.55 L C 0.69 G C 0.82 N C 0.86 G C 0.77 M E 0.58 K E 0.85 A E 0.92 I E 0.92 W E 0.92 Q E 0.92 L E 0.89 E E 0.77 Q E 0.47 K C 0.57 A E 0.54 S C 0.53 I C 0.62 A C 0.77 G C 0.84 T C 0.86 N C 0.82 S C 0.80 G C 0.70 W C 0.53 G C 0.50 N C 0.47 R E 0.52 Q E 0.69 S E 0.76 F E 0.82 I E 0.78 G E 0.73 L E 0.62 K C 0.52 G C 0.78 G C 0.78 F C 0.59 G E 0.59 T E 0.84 V E 0.88 R E 0.87 A E 0.77 G E 0.55 N E 0.47 L C 0.49 N C 0.61 T C 0.74 V H 0.59 L H 0.67 K H 0.69 D H 0.63 S H 0.56 G C 0.43 D C 0.55 N C 0.60 V C 0.62 N C 0.76 A C 0.64 W C 0.66 E C 0.63 S C 0.63 G C 0.63 S C 0.64 N C 0.63 T C 0.62 E C 0.60 D C 0.61 V C 0.53 L C 0.54 G C 0.50 L C 0.51 G C 0.55 T C 0.60 I C 0.63 G C 0.67 R C 0.69 V C 0.64 E C 0.55 S C 0.53 R C 0.53 E C 0.69 I C 0.64 S E 0.73 V E 0.88 R E 0.89 Y E 0.85 D E 0.73 S C 0.55 P C 0.69 V C 0.69 F C 0.59 A C 0.74 G C 0.60 F E 0.74 S E 0.86 G E 0.89 S E 0.90 V E 0.90 Q E 0.90 Y E 0.88 V E 0.78 P E 0.55 R C 0.69 D C 0.73 N C 0.71 A C 0.73 N C 0.77 D C 0.75 V C 0.70 D C 0.70 K C 0.74 Y C 0.77 K C 0.78 H C 0.63 T E 0.70 K E 0.83 S E 0.88 S E 0.88 R E 0.89 E E 0.89 S E 0.87 Y E 0.81 H E 0.60 A C 0.61 G C 0.74 L C 0.56 K E 0.68 Y E 0.79 E E 0.83 N E 0.84 A E 0.85 G E 0.83 F E 0.80 F E 0.70 G E 0.60 Q E 0.44 Y C 0.54 A C 0.66 G C 0.62 S C 0.59 F C 0.57 A C 0.55 K C 0.51 Y C 0.54 A C 0.56 D C 0.56 L C 0.57 N C 0.60 T C 0.61 D C 0.63 A C 0.65 E C 0.66 R C 0.67 V C 0.67 A C 0.63 V C 0.58 N C 0.56 T C 0.59 A C 0.61 N C 0.58 A C 0.59 H C 0.62 P C 0.63 V C 0.53 K C 0.48 D C 0.41 Y E 0.49 Q E 0.69 V E 0.82 H E 0.85 R E 0.89 V E 0.88 V E 0.87 A E 0.88 G E 0.88 Y E 0.87 D E 0.82 A E 0.59 N C 0.67 D C 0.50 L E 0.82 Y E 0.89 V E 0.91 S E 0.91 V E 0.91 A E 0.91 G E 0.90 Q E 0.85 Y E 0.80 E E 0.66 A E 0.56 A C 0.47 K C 0.59 N C 0.70 N C 0.70 E C 0.68 V C 0.68 G C 0.68 S C 0.65 I C 0.62 K C 0.65 G C 0.69 K C 0.64 K C 0.59 H C 0.56 E C 0.49 Q C 0.50 T C 0.52 Q E 0.76 V E 0.88 A E 0.91 A E 0.90 T E 0.89 A E 0.88 A E 0.88 Y E 0.86 R E 0.78 F E 0.49 G C 0.81 N C 0.65 V C 0.51 T H 0.41 P H 0.36 R E 0.51 V E 0.64 S E 0.69 Y E 0.72 A E 0.74 H E 0.75 G E 0.74 F E 0.65 K E 0.50 A C 0.55 K C 0.63 V C 0.62 N C 0.67 G C 0.69 V C 0.69 K C 0.70 D C 0.74 A C 0.77 N C 0.77 Y C 0.74 Q C 0.66 Y C 0.50 D E 0.56 Q E 0.86 V E 0.91 I E 0.92 V E 0.90 G E 0.88 A E 0.87 D E 0.85 Y E 0.78 D E 0.72 F E 0.56 S C 0.72 K C 0.72 R C 0.63 T C 0.41 S E 0.55 A E 0.68 L E 0.71 V E 0.73 S E 0.76 A E 0.72 G E 0.67 W E 0.69 L E 0.60 K E 0.54 Q C 0.43 G C 0.74 K C 0.85 G C 0.85 A C 0.77 G C 0.78 K C 0.61 V E 0.54 E E 0.62 Q E 0.53 T C 0.55 A C 0.65 S C 0.69 M C 0.88 END