PFRMAT SS TARGET T0399 AUTHOR SAM-T06-server METHOD This file is the result of combining several RDB files, specifically METHOD T0399.t04.dssp-ebghstl.rdb (weight 1.53986) METHOD T0399.t04.stride-ebghtl.rdb (weight 1.24869) METHOD T0399.t04.str2.rdb (weight 1.54758) METHOD T0399.t04.alpha.rdb (weight 0.659012) METHOD T0399.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0399.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0399.t2k.str2.rdb (weight 1.54758) METHOD T0399.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0399.t04.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghstl-dssp-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 132 METHOD METHOD ============================================ METHOD Comments from T0399.t04.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-ebghtl-stride-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 132 METHOD METHOD ============================================ METHOD Comments from T0399.t04.str2.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 132 METHOD METHOD ============================================ METHOD Comments from T0399.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t04-2621-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 132 METHOD METHOD ============================================ METHOD Comments from T0399.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ METHOD Comments from T0399.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ METHOD Comments from T0399.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str2-from-empty.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ METHOD Comments from T0399.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0399 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0399.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 29 METHOD METHOD ============================================ MODEL 1 M C 0.87 S C 0.74 M C 0.60 K H 0.50 K H 0.52 T H 0.59 K H 0.70 N H 0.84 W H 0.92 L H 0.95 L H 0.96 V H 0.96 F H 0.96 L H 0.96 T H 0.96 V H 0.96 T H 0.96 F H 0.95 C H 0.95 F H 0.94 L H 0.91 M H 0.87 L H 0.73 G H 0.48 C C 0.66 Q C 0.78 S C 0.79 K C 0.77 E C 0.76 D C 0.74 K C 0.71 K C 0.69 G C 0.68 G C 0.69 T C 0.60 K C 0.59 P C 0.58 S C 0.52 N C 0.52 E H 0.48 A H 0.57 A H 0.54 L H 0.47 T C 0.50 K C 0.48 T H 0.54 E H 0.55 N H 0.51 L H 0.70 D H 0.67 F H 0.66 R H 0.51 L C 0.53 S C 0.61 F C 0.58 N C 0.61 K C 0.46 I E 0.46 K E 0.54 V E 0.46 T E 0.39 T E 0.43 D E 0.46 Q E 0.40 N C 0.42 H C 0.47 F C 0.51 S C 0.59 G C 0.76 G C 0.85 T C 0.78 S C 0.80 I H 0.94 E H 0.95 Q H 0.95 L H 0.95 K H 0.94 Q H 0.92 W H 0.84 F H 0.52 G C 0.84 D C 0.88 P C 0.76 N C 0.74 K C 0.69 S C 0.71 E C 0.71 Q C 0.66 R C 0.47 N C 0.47 A C 0.54 G C 0.76 N C 0.70 I E 0.71 T E 0.86 L E 0.89 D E 0.88 S E 0.89 Y E 0.91 T E 0.90 W E 0.88 V E 0.72 K C 0.63 D C 0.85 G C 0.78 A E 0.65 V E 0.89 I E 0.92 N E 0.93 A E 0.93 Q E 0.92 L E 0.88 Y E 0.61 K C 0.88 N C 0.90 S E 0.52 T E 0.83 V E 0.84 A E 0.79 R E 0.60 S E 0.46 I H 0.40 S C 0.57 N C 0.77 F C 0.72 S C 0.62 F C 0.64 S C 0.69 R C 0.66 E C 0.69 A C 0.75 K C 0.74 I C 0.72 G C 0.85 K H 0.88 E H 0.90 D H 0.91 Y H 0.93 D H 0.91 E H 0.86 L H 0.81 K H 0.67 I C 0.63 G C 0.90 E C 0.85 S C 0.82 Y H 0.93 K H 0.95 K H 0.95 V H 0.95 V H 0.95 E H 0.93 K H 0.86 L H 0.60 G C 0.80 E C 0.87 P C 0.76 D C 0.72 V C 0.63 L C 0.54 S C 0.45 Q E 0.38 S C 0.39 M C 0.45 S C 0.56 S C 0.76 D C 0.83 K C 0.68 E C 0.47 E E 0.71 M E 0.83 Q E 0.88 T E 0.91 V E 0.90 W E 0.89 S E 0.82 S E 0.63 G E 0.49 I E 0.53 K E 0.49 T C 0.63 K C 0.80 S C 0.81 S C 0.78 S C 0.74 A C 0.59 T E 0.69 I E 0.86 E E 0.92 L E 0.92 Y E 0.92 F E 0.90 E E 0.73 N C 0.89 G C 0.88 L E 0.65 L E 0.88 K E 0.82 N E 0.79 K E 0.53 T C 0.44 Q C 0.49 K C 0.67 D C 0.76 L C 0.86 E C 0.92 END