a2m2html output for tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0399
- gi|94994542|ref|YP_602640.1|_61:205 phage protein [Streptococcus pyogenes MGAS10750]
- gi|94548050|gb|ABF38096.1| phage protein [Streptococcus pyogenes MGAS10750]
- gi|139473649|ref|YP_001128365.1|_61:205 putative lipoprotein [Streptococcus pyogenes str. Manfredo]
- gi|134271896|emb|CAM30134.1| putative lipoprotein [Streptococcus pyogenes str. Manfredo]
- gi|19746281|ref|NP_607417.1|_61:205 hypothetical protein spyM18_1310 [Streptococcus pyogenes MGAS8232]
- gi|19748469|gb|AAL97916.1| hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|15675243|ref|NP_269417.1|_61:205 hypothetical protein SPy_1290 [Streptococcus pyogenes M1 GAS]
- gi|56808027|ref|ZP_00365829.1| COG2352: Phosphoenolpyruvate carboxylase [Streptococcus pyogenes M49 591]
- gi|71903700|ref|YP_280503.1| hypothetical protein M28_Spy1035 [Streptococcus pyogenes MGAS6180]
- gi|71910867|ref|YP_282417.1| hypothetical protein M5005_Spy_1054 [Streptococcus pyogenes phage 5005.1]
- gi|94988730|ref|YP_596831.1| phage protein [Streptococcus pyogenes MGAS9429]
- gi|94990619|ref|YP_598719.1| phage protein [Streptococcus pyogenes MGAS10270]
- gi|94992553|ref|YP_600652.1| phage protein [Streptococcus pyogenes MGAS2096]
- gi|13622414|gb|AAK34138.1| hypothetical protein SPy_1290 [Streptococcus pyogenes M1 GAS]
- gi|71802795|gb|AAX72148.1| hypothetical protein M28_Spy1035 [Streptococcus pyogenes MGAS6180]
- gi|71853649|gb|AAZ51672.1| hypothetical protein M5005_Spy1054 [Streptococcus pyogenes phage 5005.1]
- gi|94542238|gb|ABF32287.1| phage protein [Streptococcus pyogenes MGAS9429]
- gi|94544127|gb|ABF34175.1| phage protein [Streptococcus pyogenes MGAS10270]
- gi|94546061|gb|ABF36108.1| phage protein [Streptococcus pyogenes MGAS2096]
- gi|50914374|ref|YP_060346.1|_61:205 unknown phage protein [Streptococcus pyogenes MGAS10394]
- gi|50903448|gb|AAT87163.1| unknown phage protein [Streptococcus pyogenes MGAS10394]
- gi|21910515|ref|NP_664783.1|_61:205 hypothetical protein SpyM3_0979 [Streptococcus pyogenes MGAS315]
- gi|28895787|ref|NP_802137.1| hypothetical protein SPs0875 [Streptococcus pyogenes SSI-1]
- gi|21904715|gb|AAM79586.1| conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|28811036|dbj|BAC63970.1| hypothetical protein [Streptococcus pyogenes SSI-1]
- gi|77409729|ref|ZP_00786389.1|_9:154 lipoprotein, putative [Streptococcus agalactiae COH1]
- gi|77171657|gb|EAO74866.1| lipoprotein, putative [Streptococcus agalactiae COH1]
- gi|22537307|ref|NP_688158.1|_61:206 lipoprotein, putative [Streptococcus agalactiae 2603V/R]
- gi|25011265|ref|NP_735660.1| hypothetical protein gbs1216 [Streptococcus agalactiae NEM316]
- gi|76798884|ref|ZP_00781091.1| lipoprotein, putative [Streptococcus agalactiae 18RS21]
- gi|77406670|ref|ZP_00783712.1| lipoprotein, putative [Streptococcus agalactiae H36B]
- gi|22534177|gb|AAN00031.1|AE014244_8 lipoprotein, putative [Streptococcus agalactiae 2603V/R]
- gi|23095689|emb|CAD46875.1| unknown [Streptococcus agalactiae NEM316]
- gi|76585753|gb|EAO62304.1| lipoprotein, putative [Streptococcus agalactiae 18RS21]
- gi|77174711|gb|EAO77538.1| lipoprotein, putative [Streptococcus agalactiae H36B]
- gi|76800382|ref|ZP_00782023.1|_54:199 conserved hypothetical protein [Streptococcus agalactiae 18RS21]
- gi|76584418|gb|EAO61382.1| conserved hypothetical protein [Streptococcus agalactiae 18RS21]
- gi|76787941|ref|YP_329852.1|_61:206 hypothetical protein SAK_1235 [Streptococcus agalactiae A909]
- gi|77414874|ref|ZP_00790984.1| putative lipoprotein [Streptococcus agalactiae 515]
- gi|76562998|gb|ABA45582.1| conserved hypothetical protein [Streptococcus agalactiae A909]
- gi|77159075|gb|EAO70276.1| putative lipoprotein [Streptococcus agalactiae 515]
- gi|153941070|ref|YP_001391563.1|_58:197 hypothetical protein CLI_2313 [Clostridium botulinum F str. Langeland]
- gi|170754377|ref|YP_001781875.1| conserved hypothetical protein [Clostridium botulinum B1 str. Okra]
- gi|152936966|gb|ABS42464.1| conserved hypothetical protein [Clostridium botulinum F str. Langeland]
- gi|169119589|gb|ACA43425.1| conserved hypothetical protein [Clostridium botulinum B1 str. Okra]
- gi|148380213|ref|YP_001254754.1|_58:197 membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|153931015|ref|YP_001384517.1| hypothetical protein CLB_2204 [Clostridium botulinum A str. ATCC 19397]
- gi|153935786|ref|YP_001388033.1| hypothetical protein CLC_2187 [Clostridium botulinum A str. Hall]
- gi|148289697|emb|CAL83802.1| putative membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|152927059|gb|ABS32559.1| conserved hypothetical protein [Clostridium botulinum A str. ATCC 19397]
- gi|152931700|gb|ABS37199.1| conserved hypothetical protein [Clostridium botulinum A str. Hall]
- gi|168180788|ref|ZP_02615452.1|_58:197 conserved hypothetical protein [Clostridium botulinum NCTC 2916]
- gi|182668531|gb|EDT80510.1| conserved hypothetical protein [Clostridium botulinum NCTC 2916]
- gi|24379624|ref|NP_721579.1|_64:206 hypothetical protein SMU.1196c [Streptococcus mutans UA159]
- gi|24377575|gb|AAN58885.1|AE014956_6 conserved hypothetical protein [Streptococcus mutans UA159]
- gi|170759226|ref|YP_001787641.1|_58:197 conserved hypothetical protein [Clostridium botulinum A3 str. Loch Maree]
- gi|169406215|gb|ACA54626.1| conserved hypothetical protein [Clostridium botulinum A3 str. Loch Maree]
- gi|168183887|ref|ZP_02618551.1|_58:197 conserved hypothetical protein [Clostridium botulinum Bf]
- gi|182672946|gb|EDT84907.1| conserved hypothetical protein [Clostridium botulinum Bf]
- gi|148380245|ref|YP_001254786.1|_58:197 membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|153934157|ref|YP_001384550.1| hypothetical protein CLB_2239 [Clostridium botulinum A str. ATCC 19397]
- gi|153934734|ref|YP_001388066.1| hypothetical protein CLC_2222 [Clostridium botulinum A str. Hall]
- gi|148289729|emb|CAL83834.1| putative membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|152930201|gb|ABS35701.1| conserved hypothetical protein [Clostridium botulinum A str. ATCC 19397]
- gi|152930648|gb|ABS36147.1| conserved hypothetical protein [Clostridium botulinum A str. Hall]
- gi|168183929|ref|ZP_02618593.1|_58:197 conserved hypothetical protein [Clostridium botulinum Bf]
- gi|182672990|gb|EDT84951.1| conserved hypothetical protein [Clostridium botulinum Bf]
- gi|90592577|ref|YP_529837.1|_61:206 hypothetical protein LGPKV5a_gp02 [Lactobacillus phage KC5a]
- gi|89891906|gb|ABD78779.1| hypothetical protein [Lactobacillus gasseri phage KC5a]
- gi|116629235|ref|YP_814407.1|_61:206 hypothetical protein LGAS_0573 [Lactobacillus gasseri ATCC 33323]
- gi|116629295|ref|YP_814467.1| hypothetical protein LGAS_0635 [Lactobacillus gasseri ATCC 33323]
- gi|116094817|gb|ABJ59969.1| hypothetical protein LGAS_0573 [Lactobacillus gasseri ATCC 33323]
- gi|116094877|gb|ABJ60029.1| hypothetical protein LGAS_0635 [Lactobacillus gasseri ATCC 33323]
- gi|116513968|ref|YP_812874.1|_58:205 hypothetical protein LBUL_0831 [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
- gi|116093283|gb|ABJ58436.1| hypothetical protein LBUL_0831 [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
- gi|104773961|ref|YP_618941.1|_58:205 hypothetical protein Ldb0913 [Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842]
- gi|103423042|emb|CAI97733.1| Conserved hypothetical protein [Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842]
- gi|3341433|emb|CAA76857.1|_95:246 hypothetical protein [Enterococcus faecalis]
- gi|163932154|ref|YP_001642344.1|_61:206 hypothetical protein LJ771_002 [Lactobacillus johnsonii prophage Lj771]
- gi|163562108|gb|ABY26964.1| hypothetical protein LJ771_002 [Lactobacillus johnsonii prophage Lj771]
- gi|15895876|ref|NP_349225.1|_56:193 Hypothetical protein, CF-17 family [Clostridium acetobutylicum ATCC 824]
- gi|15025643|gb|AAK80565.1|AE007759_3 Hypothetical protein, CF-17 family [Clostridium acetobutylicum ATCC 824]
- gi|29376973|ref|NP_816127.1|_95:246 hypothetical protein EF2480 [Enterococcus faecalis V583]
- gi|29344438|gb|AAO82197.1| conserved hypothetical protein [Enterococcus faecalis V583]
- gi|168186573|ref|ZP_02621208.1|_47:178 conserved hypothetical protein [Clostridium botulinum C str. Eklund]
- gi|169295492|gb|EDS77625.1| conserved hypothetical protein [Clostridium botulinum C str. Eklund]
- gi|77412739|ref|ZP_00788973.1|_61:164 lipoprotein, putative [Streptococcus agalactiae CJB111]
- gi|77161209|gb|EAO72286.1| lipoprotein, putative [Streptococcus agalactiae CJB111]
- gi|168180750|ref|ZP_02615414.1|_2:90 putative membrane protein [Clostridium botulinum NCTC 2916]
- gi|182668464|gb|EDT80443.1| putative membrane protein [Clostridium botulinum NCTC 2916]
- gi|116627483|ref|YP_820102.1|_2:70 hypothetical protein STER_0643 [Streptococcus thermophilus LMD-9]
- gi|116100760|gb|ABJ65906.1| Uncharacterized conserved protein [Streptococcus thermophilus LMD-9]
- gi|55822564|ref|YP_141005.1|_4:72 hypothetical protein str0594 [Streptococcus thermophilus CNRZ1066]
- gi|55738549|gb|AAV62190.1| unknown protein [Streptococcus thermophilus CNRZ1066]
- gi|55820673|ref|YP_139115.1|_4:72 hypothetical protein stu0594 [Streptococcus thermophilus LMG 18311]
- gi|55736658|gb|AAV60300.1| unknown protein [Streptococcus thermophilus LMG 18311]
- gi|153879384|ref|ZP_02004811.1|_13:87 conserved hypothetical protein [Beggiatoa sp. PS]
- gi|152064152|gb|EDN65189.1| conserved hypothetical protein [Beggiatoa sp. PS]
- gi|169185903|ref|ZP_02846065.1|_59:132 hypothetical protein Pjdr2DRAFT_1172 [Paenibacillus sp. JDR-2]
- gi|169007324|gb|EDS54173.1| hypothetical protein Pjdr2DRAFT_1172 [Paenibacillus sp. JDR-2]
- gi|110602381|ref|ZP_01390485.1|_19:75 conserved hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Geobacter sp. FRC-32]
- gi|110546907|gb|EAT60229.1| conserved hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Geobacter sp. FRC-32]
- gi|118579387|ref|YP_900637.1|_20:78 hypothetical protein Ppro_0950 [Pelobacter propionicus DSM 2379]
- gi|118502097|gb|ABK98579.1| conserved hypothetical protein [Pelobacter propionicus DSM 2379]
- gi|158335308|ref|YP_001516480.1|_49:113 hypothetical protein AM1_2152 [Acaryochloris marina MBIC11017]
- gi|158305549|gb|ABW27166.1| conserved hypothetical protein [Acaryochloris marina MBIC11017]
- gi|148262331|ref|YP_001229037.1|_21:78 hypothetical protein Gura_0248 [Geobacter uraniumreducens Rf4]
- gi|146395831|gb|ABQ24464.1| hypothetical protein Gura_0248 [Geobacter uraniireducens Rf4]
- gi|65318347|ref|ZP_00391306.1|_73:121 COG0124: Histidyl-tRNA synthetase [Bacillus anthracis str. A2012]
- gi|30261065|ref|NP_843442.1|_73:121 lipoprotein, putative [Bacillus anthracis str. Ames]
- gi|47526221|ref|YP_017571.1| lipoprotein, putative [Bacillus anthracis str. 'Ames Ancestor']
- gi|49183906|ref|YP_027158.1| lipoprotein, putative [Bacillus anthracis str. Sterne]
- gi|165871673|ref|ZP_02216318.1| putative lipoprotein [Bacillus anthracis str. A0488]
- gi|167635450|ref|ZP_02393763.1| putative lipoprotein [Bacillus anthracis str. A0442]
- gi|167638978|ref|ZP_02397252.1| putative lipoprotein [Bacillus anthracis str. A0193]
- gi|168172973|ref|ZP_02608202.1| lipoprotein, putative [Bacillus anthracis Tsiankovskii-I]
- gi|170687557|ref|ZP_02878773.1| putative lipoprotein [Bacillus anthracis str. A0465]
- gi|170707981|ref|ZP_02898430.1| putative lipoprotein [Bacillus anthracis str. A0389]
- gi|177653558|ref|ZP_02935732.1| putative lipoprotein [Bacillus anthracis str. A0174]
- gi|30254679|gb|AAP24928.1| lipoprotein, putative [Bacillus anthracis str. Ames]
- gi|47501369|gb|AAT30045.1| lipoprotein, putative [Bacillus anthracis str. 'Ames Ancestor']
- gi|49177833|gb|AAT53209.1| lipoprotein, putative [Bacillus anthracis str. Sterne]
- gi|164712574|gb|EDR18106.1| putative lipoprotein [Bacillus anthracis str. A0488]
- gi|167513108|gb|EDR88480.1| putative lipoprotein [Bacillus anthracis str. A0193]
- gi|167529068|gb|EDR91822.1| putative lipoprotein [Bacillus anthracis str. A0442]
- gi|170127141|gb|EDS96019.1| putative lipoprotein [Bacillus anthracis str. A0389]
- gi|170668370|gb|EDT19117.1| putative lipoprotein [Bacillus anthracis str. A0465]
- gi|172081362|gb|EDT66436.1| putative lipoprotein [Bacillus anthracis str. A0174]
- gi|56478050|ref|YP_159639.1|_23:79 hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Azoarcus sp. EbN1]
- gi|56314093|emb|CAI08738.1| hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Azoarcus sp. EbN1]
- gi|119898520|ref|YP_933733.1|_15:78 conserved hypothetical secreted protein [Azoarcus sp. BH72]
- gi|119670933|emb|CAL94846.1| conserved hypothetical secreted protein [Azoarcus sp. BH72]
- gi|53802384|ref|YP_112844.1|_25:62 lipoprotein, putative [Methylococcus capsulatus str. Bath]
- gi|53756145|gb|AAU90436.1| putative lipoprotein [Methylococcus capsulatus str. Bath]

              10        20         30             40              50   
              |         |          |              |               |   
   1 VTTDQNHFSGGTSIEQLKQWFG.DPNKSEQRNAGN.....ITLDSYTW.VKDG.....AVINAQ.
   2 --TVDSSFTGGTSLEELISLFG.EPNQHDPKTAGE.....VTIDAYTW.QFDQ.....VTLTVN.
   3 --TVDSSFTGGTSLEELISLFG.EPNQHDPKTAGE.....VTIDAYTW.QFDQ.....VTLTVN.
   4 --TVDSSFTGGTSLEELISLFG.EPSQHDPKTAGE.....VTIDAYTW.QFDQ.....VTLTVN.
   5 --TVDSSFTGGTSLEELISLFG.EPSQHDPKTAGE.....VTIDAYTW.QFDQ.....VTLTVN.
   6 --TVDSSFTGGTSLEELISLFG.EPSQHDPKTAGE.....VTINAYTW.QFDQ.....VTLTVN.
   7 --TVDSSFTGGTSLEELISLFG.EPSQHDPKTAGE.....VTIDAYTW.QFDQ.....VTLTVN.
   8 -GVKANNFKGGTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRW.NVDD.....ISITIQ.
   9 -GVKANNFKGGTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRW.NVDD.....ISITIQ.
  10 -GVKANNFKGGTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRW.NVDD.....ISITIQ.
  11 -GVKANNFKGGTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRW.NVDD.....ISITIQ.
  12 -YEKFCKIKIGSTYEEVKSILG.EYKESKESEING.....MKVVIYSW.YNDD.....NSNMEV.
  13 -YEKFCKIKIGSTYEEVKSILG.EYKESKESEIND.....MKVVIYSW.YNDD.....NSNMEV.
  14 -YEKFCKIKIGSTYEEVKSILG.EYKESKESEING.....MKVVIYSW.YNDD.....NSNMEV.
  15 ----QNHFSGGTSIEQLKQWFG.DPNKSEQRNAGN.....ITLDSYTW.VKDG.....AVINAQ.
  16 -YEKFCKIKIGSTYEEVKSILG.EYKESKESEING.....MKVVIYTW.YNDD.....NSNMEV.
  17 -YEKFCKIKIGSTYEEVKSILG.EYKESKESEIDG.....MKVVIYTW.YNDD.....NSNMEV.
  18 -YEKFSKVKMGSTYEDVKNMLG.EAKESTSSEMGG.....IKTVIYTWdNGDG.....SNMNVT.
  19 -YEKFSKVKMGSTYEDVKNMLG.EGKESTSSEMGG.....IKTVIYTWdNGDG.....SNMNVT.
  20 -GELSKHGEGGSTIQDVEKLLG.KANTTDTTTVES.....YKTKSYIW.NKGA.....VTVTVQ.
  21 -GELSNHGEGGSTIQDVEKLLG.KANTTDTTTVDS.....YKTKSYIW.NKGA.....VTVTVQ.
  22 ---IKVVEKTGSTPSQVTDLLG.READAKSKAKTSkl6tiYTWEGVQN.GSAG.....ANLAVE.
  23 ---IKVVEKTGSTPSQVTDLLG.READAKSKAKTSkl6tiYTWEGVQN.GSAG.....ANLAVE.
  24 VGDIMNSSEGGSTEDEVKAILG.EPASSSTTDIQG.....ISTTTLSW.TNVKggdllASITVS.
  25 -GNFLSQGEGGSTIDEVKQLLG.SPTSTTTTSSNG.....VKLKQLTW.TKGA.....VTVAIQt
  26 --KKFLRINMGMNYKSVENILG.VSEKTGQINDKR.....ELMNHQWK.NSDD.....SYIVVI.
  27 VGDIMNSSEGGSTEDEVKAILG.EPASSSTTDIQG.....ISTTTLSW.TNVKggdllASITVS.
  28 -YDNFLKVEIGSNYNDVVKILG.KESYMDSAIING.....LKNTTYIW.KING.....TEKNIF.
  29 -GVKANNFKGGTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRW.NVDD.....ISITIQ.
  30 ----------GSTYEEVKNMLG.EGKESTSSEMGG.....IKTVIYTWdNGDG.....SNMNVT.
  31 ----------------------.------------.....--------.----.....------.
  32 ----------------------.------------.....--------.----.....------.
  33 ----------------------.------------.....--------.----.....------.
  34 ----------------------.------------.....--------.----.....------.
  35 ----------------------.------------.....--------.----.....------.
  36 ----------------------.------------.....--------.----.....------.
  37 ----------------------.------------.....--------.----.....------.
  38 ----------------------.------------.....--------.----.....------.
  39 ----------------------.------------.....--------.----.....------.
  40 ----------------------.------------.....--------.----.....------.
  41 ----------------------.------------.....--------.----.....------.
  42 ----------------------.------------.....--------.----.....------.
  43 ----------------------.------------.....--------.----.....------.
  44 ----------------------.------------.....--------.----.....------.


            60         70        80          90        100       110   
            |          |         |           |          |         |   
   1 LYKNSTVARSISNFSFS.REAKIGKEDYDELKIGESY..KKVVEKLG.EPDVLSQSMSSDKEEMQ
   2 LYQNSSIVKTISNFTFA.RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   3 LYQNSSIVKTISNFTFA.RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   4 LYQNSSIVKTISNFTFA.RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   5 LYQNSSIVKTISNFTFA.RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   6 LYQNSSIVKTISNFTFA.RELGLSQKEYQQLQKGMSY..EDAKKILT.EPDNYSQASSSDHQTLQ
   7 LYQNSSIVKTISNFTFA.RELGLSQKEYQQLQKRMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   8 LLNDSSIVRSISNFKFI.RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
   9 LLNDSSIVRSISNFKFI.RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
  10 LLNDSSIVRSISNFKFI.RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
  11 LLNDSSIVRSISNFKFI.RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
  12 IVKNNKVIGKAQAGLSM.GKADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  13 IVKNNKVIGKAQAGLSM.GKADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  14 IVKNNKVIGKAQAGLSM.GKADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  15 LYKNSTVARSISNFSFS.REAKIGKEDYDELKIGESY..KKVVEKLG.EPDVLSQSMSSDKEEMQ
  16 IVKNNKVIGKAQADLSM.GKADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  17 IVKNNKVIGKAQAGLSM.GKADVNLIKYTKIRTGMDY..SKVKEILG.DGKLMSISKTNGSTKSI
  18 FQNNKALAKAQAGLSRK.R-ADVNMEKYNKIQTGMDY..NKVKEILG.DGELMSISEVGGSNTSI
  19 FQNNKALAKAQAGLSRE.K-ADVNMEKYNTIQTGMDY..NKIKEILG.AGELMSISEVGGSNTSI
  20 FEPDKVVTKDITGFKWGkRDEKLDLAAFNSIQDGASY..DDIVKKYG.EPDSLNESLLLGTKTVT
  21 FEPDKAVTKDITGFKWGkRDEKLDLAAFNSIQDGATY..DDIVKKYG.EPDSLNESLLLGTKTVT
  22 FANGVAIAKQISGLVVN.RSKQITPKDYKSLKKGMTQ..EEVEAIVG.KPNGYSESDYSNSEVVL
  23 FANGVAIAKQISGLVVN.RSKQITPKDYKSLKKGMTQ..EEVEAIVG.KPNGYSESDYSNSEVVL
  24 FSDGKAASKSVSGLKVA.KHDKVTADQVNNIATDGSYseEQARKDLG.DPTGITSTNINGEKNDT
  25 LDSNKVVSKEITGFKWGkRDEKLTLGEFNNIADGSTY..QSLVDKYG.EPDGLHEANVAGTKITN
  26 TKNNYVVSKIEIGLE-K.INANISRVKYKKISRGMSY..EKVKNLVG.KGELLSETNLMGSNSKM
  27 FSDGKAASKSVSGLKVA.KHDKVTADQVNNIATDGSYseEQARKDLG.DPTGITSTNINGEKNDT
  28 ITFRNGIVITKEQYKLNdKFSILSNKKINSLKKGMSY..NEVKNILG.EGILRSEEKETQVYSWF
  29 LLNDSSIVRSISNFKFI.RDANITTKDYNSLKNXXSY..NKVKELLG.EPDDISQA---------
  30 FQNNKALAKAQAGLSRE.R-ADVNAEKYNRIQTGMDY..NKVKEILG.DGE--------------
  31 -----------------.---------YEDLKNGTSY..DNAVKILG.VPDVYSIAVSSDATMTQ
  32 -----------------.---------YEDLKNGTSY..DNAVKTLG.VPDVYSIAVSSDATMTQ
  33 -----------------.---------YEDLKNGTSY..DNAVQTLG.VPDVYSIAVSSDATMTQ
  34 ------IAIVLSAFLFG.CFSKINQENYAKIENGMTM..EQVKDILG.EPTESQTAGIGSLSGTN
  35 -----------------.----ITKENYDKVKNGMSY..EEVVKIIGsEGEIVTETGEKGDDMYG
  36 -----------------.-CSKLTTENYEKIKMGMDY..GEVAGILG.KPDSCSEALFAKSCIW-
  37 -----------------.-CSKLTQENYAKLKMGLGY..GEVVTILG.KPDSCSEALFAKSCVW-
  38 -----------------.NKELVSQEKYKQLKLDMSY..EDVKKIMG.SPGKVKKFPGQPSTETT
  39 -----------------.--SKLTMENYSKIKTGIGY..TEVVKILG.KPDNCSEALFVRNCV--
  40 -----------------.---------------GEKY..EDVVAKFG.EPDNKAESQAGDIKMII
  41 -----------------.---------------GEKY..EDVVAKFG.EPDNKAESQAGDIKMII
  42 -----------------.----VTVENYDKIRVGMTY..DEVKQLLG.APNRCSDVMTVKSCTW-
  43 -----------------.GCNKLTPENYDKLRMGMHY..AEVKSILG.EPTRCSDLLAVKA----
  44 -----------------.-ENKVTRENYDKLAIGMEY..SKVVELLG.EPENCQSVVSVK-----


          120        130       140       
           |          |         |       
   1 TVWSSGIKTK.SSSATIELYFENGLLKNKTQKDLE
   2 AIWVSGLKTD.TSGANISLVFENNQLTEMSQVGLE
   3 AIWVSGLKTD.TSGANISLVFENNQLTEMSQVGLE
   4 AIWVSGLKTD.TSGANISLVFENNQLTEMSQVGLE
   5 AIWVSGLKTD.TSGANISLVFENNQLTEMSQVGLE
   6 AIWVSGLKTD.TSGANISLVFENNQLTEMSQVGLE
   7 AIWVSGLKTD.TSGANISLVFENNQLTEMSQVGLE
   8 AAWISGIQSS.DSDPGINLTFENDKLTNKQQHGL-
   9 AAWISGIQSS.DSDPGINLTFENDKLTNKQQHGL-
  10 AAWISGIQSS.DSDPGINLTFENDKLTNKQQHGL-
  11 AAWISGIQSS.DSDPGINLTFENDKLTNKQQHGL-
  12 YLWA-----N.PNGTNMNVTFQNGKVTAKNRLGL-
  13 YLWA-----N.PNGTNMNVTFQNGKVTAKNRLGL-
  14 YLWA-----N.PNGTNMNVTFQNGKVTAKNRLGL-
  15 TVWSSGIKTK.SSSATIELYFENGLLKNKTQKDLE
  16 YLWA-----N.PNGTNMNVTFQNGKVTAKNRLGL-
  17 YLWA-----N.PNGTNMNVTFQNGKVTTKNRLGL-
  18 YSWV-----N.SNGTNINVTFQDGKSAAKAQFGL-
  19 YSWV-----N.SNGTNMNVTFQDGKSAAKAQFGL-
  20 ALWYTGIKGK.GAGANASLTFENGALTSKTQTDL-
  21 GLWYTGIKGK.ADGAFASLTFENGALTSKTQTDL-
  22 WLYTSGLK-S.DDQANFYVTFQKNKLVAKKAQNF-
  23 WLYTSGLK-S.DDQANFYVTFQKNKLVAKKAQNF-
  24 LIWMKNLD-G.DLGATVTVSFSNGNAISKSSSGL-
  25 AVWLTGIK-G.DDGASATFSFENDKLSSKTQTKL-
  26 YQWV-----N.SDGSSMNITFTNGIVDYKTEKKL-
  27 LIWMKNLD-G.DLGATVTVSFSNGSAISKSSSGL-
  28 NNDSSYINCT.FKNDKLNIF---------------
  29 ----------.------------------------
  30 ----------.------------------------
  31 ALWSSNLVTKkGKTGSLTLNFKNGTLENKSQENL-
  32 ALWSSNLVTKkGKTGSLTLNFKNGTLENKSQENL-
  33 ALWSSNLVTKkGKTGSLTLNFKNGTLENKSQENL-
  34 AIW------K.SDSVTIKLTFVNSKVQ--------
  35 IAVLY-ENKG.SSLSNATFIFLGDKLQSKSQYGLE
  36 ---------G.NEQKNITVNFVGDK----------
  37 ---------G.DEQKNITVNFAGDRVV--------
  38 YVWK----QK.NSSYRILVTLKDGKV---------
  39 --------WG.NEQKNITVSFVGDKAI--------
  40 ASWTKNVN-G.DLGANFNVTFT-------------
  41 ASWTKNVN-G.DLGANFNVTFT-------------
  42 ---------G.DEKRHVQVSFVADQVVL-------
  43 ------CTWG.DDARYINVNFVADQAVLLNS----
  44 ----------.------------------------