a2m2html output for tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0399 Putative beta-lactamase inhibitor protein, Streptococcus mutans, 206 residues
- gi|76787941|ref|YP_329852.1|_1:206 hypothetical protein SAK_1235 [Streptococcus agalactiae A909]
- gi|77414874|ref|ZP_00790984.1| putative lipoprotein [Streptococcus agalactiae 515]
- gi|76562998|gb|ABA45582.1| conserved hypothetical protein [Streptococcus agalactiae A909]
- gi|77159075|gb|EAO70276.1| putative lipoprotein [Streptococcus agalactiae 515]
- gi|22537307|ref|NP_688158.1|_1:206 lipoprotein, putative [Streptococcus agalactiae 2603V/R]
- gi|25011265|ref|NP_735660.1| hypothetical protein gbs1216 [Streptococcus agalactiae NEM316]
- gi|76798884|ref|ZP_00781091.1| lipoprotein, putative [Streptococcus agalactiae 18RS21]
- gi|77406670|ref|ZP_00783712.1| lipoprotein, putative [Streptococcus agalactiae H36B]
- gi|22534177|gb|AAN00031.1|AE014244_8 lipoprotein, putative [Streptococcus agalactiae 2603V/R]
- gi|23095689|emb|CAD46875.1| unknown [Streptococcus agalactiae NEM316]
- gi|76585753|gb|EAO62304.1| lipoprotein, putative [Streptococcus agalactiae 18RS21]
- gi|77174711|gb|EAO77538.1| lipoprotein, putative [Streptococcus agalactiae H36B]
- gi|139473649|ref|YP_001128365.1|_4:205 putative lipoprotein [Streptococcus pyogenes str. Manfredo]
- gi|134271896|emb|CAM30134.1| putative lipoprotein [Streptococcus pyogenes str. Manfredo]
- gi|94994542|ref|YP_602640.1|_4:205 phage protein [Streptococcus pyogenes MGAS10750]
- gi|94548050|gb|ABF38096.1| phage protein [Streptococcus pyogenes MGAS10750]
- gi|15675243|ref|NP_269417.1|_4:205 hypothetical protein SPy_1290 [Streptococcus pyogenes M1 GAS]
- gi|56808027|ref|ZP_00365829.1| COG2352: Phosphoenolpyruvate carboxylase [Streptococcus pyogenes M49 591]
- gi|71903700|ref|YP_280503.1| hypothetical protein M28_Spy1035 [Streptococcus pyogenes MGAS6180]
- gi|71910867|ref|YP_282417.1| hypothetical protein M5005_Spy_1054 [Streptococcus pyogenes phage 5005.1]
- gi|94988730|ref|YP_596831.1| phage protein [Streptococcus pyogenes MGAS9429]
- gi|94990619|ref|YP_598719.1| phage protein [Streptococcus pyogenes MGAS10270]
- gi|94992553|ref|YP_600652.1| phage protein [Streptococcus pyogenes MGAS2096]
- gi|13622414|gb|AAK34138.1| hypothetical protein SPy_1290 [Streptococcus pyogenes M1 GAS]
- gi|71802795|gb|AAX72148.1| hypothetical protein M28_Spy1035 [Streptococcus pyogenes MGAS6180]
- gi|71853649|gb|AAZ51672.1| hypothetical protein M5005_Spy1054 [Streptococcus pyogenes phage 5005.1]
- gi|94542238|gb|ABF32287.1| phage protein [Streptococcus pyogenes MGAS9429]
- gi|94544127|gb|ABF34175.1| phage protein [Streptococcus pyogenes MGAS10270]
- gi|94546061|gb|ABF36108.1| phage protein [Streptococcus pyogenes MGAS2096]
- gi|19746281|ref|NP_607417.1|_4:205 hypothetical protein spyM18_1310 [Streptococcus pyogenes MGAS8232]
- gi|19748469|gb|AAL97916.1| hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|50914374|ref|YP_060346.1|_4:205 unknown phage protein [Streptococcus pyogenes MGAS10394]
- gi|50903448|gb|AAT87163.1| unknown phage protein [Streptococcus pyogenes MGAS10394]
- gi|21910515|ref|NP_664783.1|_4:205 hypothetical protein SpyM3_0979 [Streptococcus pyogenes MGAS315]
- gi|28895787|ref|NP_802137.1| hypothetical protein SPs0875 [Streptococcus pyogenes SSI-1]
- gi|21904715|gb|AAM79586.1| conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|28811036|dbj|BAC63970.1| hypothetical protein [Streptococcus pyogenes SSI-1]
- gi|76800382|ref|ZP_00782023.1|_4:199 conserved hypothetical protein [Streptococcus agalactiae 18RS21]
- gi|76584418|gb|EAO61382.1| conserved hypothetical protein [Streptococcus agalactiae 18RS21]
- gi|24379624|ref|NP_721579.1|_1:206 hypothetical protein SMU.1196c [Streptococcus mutans UA159]
- gi|24377575|gb|AAN58885.1|AE014956_6 conserved hypothetical protein [Streptococcus mutans UA159]
- gi|153941070|ref|YP_001391563.1|_7:197 hypothetical protein CLI_2313 [Clostridium botulinum F str. Langeland]
- gi|170754377|ref|YP_001781875.1| conserved hypothetical protein [Clostridium botulinum B1 str. Okra]
- gi|152936966|gb|ABS42464.1| conserved hypothetical protein [Clostridium botulinum F str. Langeland]
- gi|169119589|gb|ACA43425.1| conserved hypothetical protein [Clostridium botulinum B1 str. Okra]
- gi|168180788|ref|ZP_02615452.1|_7:197 conserved hypothetical protein [Clostridium botulinum NCTC 2916]
- gi|182668531|gb|EDT80510.1| conserved hypothetical protein [Clostridium botulinum NCTC 2916]
- gi|168183887|ref|ZP_02618551.1|_7:197 conserved hypothetical protein [Clostridium botulinum Bf]
- gi|182672946|gb|EDT84907.1| conserved hypothetical protein [Clostridium botulinum Bf]
- gi|148380213|ref|YP_001254754.1|_7:197 membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|153931015|ref|YP_001384517.1| hypothetical protein CLB_2204 [Clostridium botulinum A str. ATCC 19397]
- gi|153935786|ref|YP_001388033.1| hypothetical protein CLC_2187 [Clostridium botulinum A str. Hall]
- gi|148289697|emb|CAL83802.1| putative membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|152927059|gb|ABS32559.1| conserved hypothetical protein [Clostridium botulinum A str. ATCC 19397]
- gi|152931700|gb|ABS37199.1| conserved hypothetical protein [Clostridium botulinum A str. Hall]
- gi|170759226|ref|YP_001787641.1|_7:197 conserved hypothetical protein [Clostridium botulinum A3 str. Loch Maree]
- gi|169406215|gb|ACA54626.1| conserved hypothetical protein [Clostridium botulinum A3 str. Loch Maree]
- gi|148380245|ref|YP_001254786.1|_7:197 membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|153934157|ref|YP_001384550.1| hypothetical protein CLB_2239 [Clostridium botulinum A str. ATCC 19397]
- gi|153934734|ref|YP_001388066.1| hypothetical protein CLC_2222 [Clostridium botulinum A str. Hall]
- gi|148289729|emb|CAL83834.1| putative membrane protein [Clostridium botulinum A str. ATCC 3502]
- gi|152930201|gb|ABS35701.1| conserved hypothetical protein [Clostridium botulinum A str. ATCC 19397]
- gi|152930648|gb|ABS36147.1| conserved hypothetical protein [Clostridium botulinum A str. Hall]
- gi|168183929|ref|ZP_02618593.1|_7:197 conserved hypothetical protein [Clostridium botulinum Bf]
- gi|182672990|gb|EDT84951.1| conserved hypothetical protein [Clostridium botulinum Bf]
- gi|90592577|ref|YP_529837.1|_1:206 hypothetical protein LGPKV5a_gp02 [Lactobacillus phage KC5a]
- gi|89891906|gb|ABD78779.1| hypothetical protein [Lactobacillus gasseri phage KC5a]
- gi|116629235|ref|YP_814407.1|_1:206 hypothetical protein LGAS_0573 [Lactobacillus gasseri ATCC 33323]
- gi|116629295|ref|YP_814467.1| hypothetical protein LGAS_0635 [Lactobacillus gasseri ATCC 33323]
- gi|116094817|gb|ABJ59969.1| hypothetical protein LGAS_0573 [Lactobacillus gasseri ATCC 33323]
- gi|116094877|gb|ABJ60029.1| hypothetical protein LGAS_0635 [Lactobacillus gasseri ATCC 33323]
- gi|77409729|ref|ZP_00786389.1|_3:154 lipoprotein, putative [Streptococcus agalactiae COH1]
- gi|77171657|gb|EAO74866.1| lipoprotein, putative [Streptococcus agalactiae COH1]
- gi|163932154|ref|YP_001642344.1|_1:206 hypothetical protein LJ771_002 [Lactobacillus johnsonii prophage Lj771]
- gi|163562108|gb|ABY26964.1| hypothetical protein LJ771_002 [Lactobacillus johnsonii prophage Lj771]
- gi|77412739|ref|ZP_00788973.1|_1:165 lipoprotein, putative [Streptococcus agalactiae CJB111]
- gi|77161209|gb|EAO72286.1| lipoprotein, putative [Streptococcus agalactiae CJB111]
- gi|116513968|ref|YP_812874.1|_6:205 hypothetical protein LBUL_0831 [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
- gi|116093283|gb|ABJ58436.1| hypothetical protein LBUL_0831 [Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365]
- gi|104773961|ref|YP_618941.1|_6:205 hypothetical protein Ldb0913 [Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842]
- gi|103423042|emb|CAI97733.1| Conserved hypothetical protein [Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842]
- gi|15895876|ref|NP_349225.1|_1:193 Hypothetical protein, CF-17 family [Clostridium acetobutylicum ATCC 824]
- gi|15025643|gb|AAK80565.1|AE007759_3 Hypothetical protein, CF-17 family [Clostridium acetobutylicum ATCC 824]
- gi|29376973|ref|NP_816127.1|_60:246 hypothetical protein EF2480 [Enterococcus faecalis V583]
- gi|29344438|gb|AAO82197.1| conserved hypothetical protein [Enterococcus faecalis V583]
- gi|3341433|emb|CAA76857.1|_60:246 hypothetical protein [Enterococcus faecalis]
- gi|168186573|ref|ZP_02621208.1|_8:175 conserved hypothetical protein [Clostridium botulinum C str. Eklund]
- gi|169295492|gb|EDS77625.1| conserved hypothetical protein [Clostridium botulinum C str. Eklund]
- gi|168180750|ref|ZP_02615414.1|_2:90 putative membrane protein [Clostridium botulinum NCTC 2916]
- gi|182668464|gb|EDT80443.1| putative membrane protein [Clostridium botulinum NCTC 2916]
- gi|77412604|ref|ZP_00788889.1|_1:95 lipoprotein, putative [Streptococcus agalactiae CJB111]
- gi|77161344|gb|EAO72370.1| lipoprotein, putative [Streptococcus agalactiae CJB111]
- gi|158335308|ref|YP_001516480.1|_35:113 hypothetical protein AM1_2152 [Acaryochloris marina MBIC11017]
- gi|158305549|gb|ABW27166.1| conserved hypothetical protein [Acaryochloris marina MBIC11017]
- gi|116627483|ref|YP_820102.1|_2:70 hypothetical protein STER_0643 [Streptococcus thermophilus LMD-9]
- gi|116100760|gb|ABJ65906.1| Uncharacterized conserved protein [Streptococcus thermophilus LMD-9]
- gi|55822564|ref|YP_141005.1|_4:72 hypothetical protein str0594 [Streptococcus thermophilus CNRZ1066]
- gi|55738549|gb|AAV62190.1| unknown protein [Streptococcus thermophilus CNRZ1066]
- gi|55820673|ref|YP_139115.1|_4:72 hypothetical protein stu0594 [Streptococcus thermophilus LMG 18311]
- gi|55736658|gb|AAV60300.1| unknown protein [Streptococcus thermophilus LMG 18311]
- gi|153879384|ref|ZP_02004811.1|_14:87 conserved hypothetical protein [Beggiatoa sp. PS]
- gi|152064152|gb|EDN65189.1| conserved hypothetical protein [Beggiatoa sp. PS]
- gi|169185903|ref|ZP_02846065.1|_59:132 hypothetical protein Pjdr2DRAFT_1172 [Paenibacillus sp. JDR-2]
- gi|169007324|gb|EDS54173.1| hypothetical protein Pjdr2DRAFT_1172 [Paenibacillus sp. JDR-2]
- gi|30261065|ref|NP_843442.1|_10:120 lipoprotein, putative [Bacillus anthracis str. Ames]
- gi|47526221|ref|YP_017571.1| lipoprotein, putative [Bacillus anthracis str. 'Ames Ancestor']
- gi|49183906|ref|YP_027158.1| lipoprotein, putative [Bacillus anthracis str. Sterne]
- gi|165871673|ref|ZP_02216318.1| putative lipoprotein [Bacillus anthracis str. A0488]
- gi|167635450|ref|ZP_02393763.1| putative lipoprotein [Bacillus anthracis str. A0442]
- gi|167638978|ref|ZP_02397252.1| putative lipoprotein [Bacillus anthracis str. A0193]
- gi|168172973|ref|ZP_02608202.1| lipoprotein, putative [Bacillus anthracis Tsiankovskii-I]
- gi|170687557|ref|ZP_02878773.1| putative lipoprotein [Bacillus anthracis str. A0465]
- gi|170707981|ref|ZP_02898430.1| putative lipoprotein [Bacillus anthracis str. A0389]
- gi|177653558|ref|ZP_02935732.1| putative lipoprotein [Bacillus anthracis str. A0174]
- gi|30254679|gb|AAP24928.1| lipoprotein, putative [Bacillus anthracis str. Ames]
- gi|47501369|gb|AAT30045.1| lipoprotein, putative [Bacillus anthracis str. 'Ames Ancestor']
- gi|49177833|gb|AAT53209.1| lipoprotein, putative [Bacillus anthracis str. Sterne]
- gi|164712574|gb|EDR18106.1| putative lipoprotein [Bacillus anthracis str. A0488]
- gi|167513108|gb|EDR88480.1| putative lipoprotein [Bacillus anthracis str. A0193]
- gi|167529068|gb|EDR91822.1| putative lipoprotein [Bacillus anthracis str. A0442]
- gi|170127141|gb|EDS96019.1| putative lipoprotein [Bacillus anthracis str. A0389]
- gi|170668370|gb|EDT19117.1| putative lipoprotein [Bacillus anthracis str. A0465]
- gi|172081362|gb|EDT66436.1| putative lipoprotein [Bacillus anthracis str. A0174]
- gi|110602381|ref|ZP_01390485.1|_21:75 conserved hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Geobacter sp. FRC-32]
- gi|110546907|gb|EAT60229.1| conserved hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Geobacter sp. FRC-32]
- gi|148262331|ref|YP_001229037.1|_22:78 hypothetical protein Gura_0248 [Geobacter uraniumreducens Rf4]
- gi|146395831|gb|ABQ24464.1| hypothetical protein Gura_0248 [Geobacter uraniireducens Rf4]
- gi|118579387|ref|YP_900637.1|_22:78 hypothetical protein Ppro_0950 [Pelobacter propionicus DSM 2379]
- gi|118502097|gb|ABK98579.1| conserved hypothetical protein [Pelobacter propionicus DSM 2379]
- gi|56478050|ref|YP_159639.1|_23:78 hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Azoarcus sp. EbN1]
- gi|56314093|emb|CAI08738.1| hypothetical protein of beta-lactamase-inhibitor family (Pfam) [Azoarcus sp. EbN1]
- gi|125718961|ref|YP_001036094.1|_248:385 hypothetical protein SSA_2178 [Streptococcus sanguinis SK36]
- gi|125498878|gb|ABN45544.1| Uncharacterized protein [Streptococcus sanguinis SK36]
- gi|65318347|ref|ZP_00391306.1|_41:120 COG0124: Histidyl-tRNA synthetase [Bacillus anthracis str. A2012]
- gi|119898520|ref|YP_933733.1|_18:77 conserved hypothetical secreted protein [Azoarcus sp. BH72]
- gi|119670933|emb|CAL94846.1| conserved hypothetical secreted protein [Azoarcus sp. BH72]
- gi|53802384|ref|YP_112844.1|_25:60 lipoprotein, putative [Methylococcus capsulatus str. Bath]
- gi|53756145|gb|AAU90436.1| putative lipoprotein [Methylococcus capsulatus str. Bath]

              10        20        30        40        50        60     
              |         |         |         |         |         |     
   1 MSMKKTKNWLLVFLTVTFCFLMLGCQSKEDKKGGTKPSNEAALTKTENLDFRLSFNKIKVTTDQN
   2 MIPLKKITVGTIICLSFLGLTACSSSNTQQTSTSKSNVSQHKNIKADHEELRLKFNKVKLGVKAN
   3 MIPLKKITVGTIVCLSFLGLTACSSSNTQQTSTSKSNVSQHKNIKADHEELRLKFNKVKLGVKAN
   4 ----KHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDS
   5 ----KHLLTLLLISFFTSFLVACSTTKDKEPQPSDSENITPRLHQAAHQDKRANFEKIKLATVDS
   6 ----KHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDS
   7 ----KHLLTLLLISFFTSFLVACSTTKDKKPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDS
   8 ----KHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDS
   9 ----KHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDS
  10 ----------TIVCLSFLGLTACSSSNTQQTXTSKSNVSQHKNIKADHEELRLKFNKVKLGVKAN
  11 MSMKKTKNWLLVFLTVTFCFLMLGCQSKEDKKGGTKPSNEAALTKTENLDFRLSFNKIKVTTDQN
  12 -EPFYKKIWFWIIAIVIVCGVASYGDSKKINITDTKNSAKTETKKDDTRKV--------TYEKFC
  13 -EPFYKKIWFWIIAIVIICGVASYGDSKKINITDTKNSDKTEIKKDDTRKV--------TYEKFC
  14 -EPFYKKIWFWIIAIVIVFGVASYGGSKKINITDTKNSPKTEIKKDDTRKV--------TYEKFC
  15 -EPFYKKIWFWIIAIVIVCGVASYGDSKKINITDTKNSAKTDTKKDDTRKV--------TYEKFC
  16 -EPFYKKIWFWIIAMVIVFGVANYGGSKKINIIDTKNSSETGIKKDDTRKV--------TYEKFC
  17 -KPFYKKFWIWIIAIIIIGGVIGSNGSKKTGNTSNNSSTKKEAKKEDTRKI--------TYEKFS
  18 -KPFYKKFWFWIIAIIIIGGVIGSNGSKKTGNTSNNNSTKKEAKKEDTRKI--------TYEKFS
  19 MKKKYLVAATGLALLGLSMSACSSNSGSKSDSATTSQQKKKNETISQNKELREKFDQVKVGELSK
  20 MKKKYLVAATGLALLGLSMSACSSNSGSKSDSAKTSQKKKKNETISQNKELREKFDQIKVGELSN
  21 ------------------------------------------------------FNKVKLGVKAN
  22 MKKKYLVAATGLALLGLSLSACSSNSSKGNSEKTTEQSKKKNKVISQNKELREKFDQIKVGNFLS
  23 MIPLKKITVGTIVCLSFLGLTACSSSNTQQTSTSKSNVSQHKNIKADHEELRLKFNKVKLGVKAN
  24 ----------LLIAFAALALTACSSKKATTDSESDKKAASSISSSNVVKQTSNKINLTNYKKIKV
  25 ----------LLIAFAALALTACSSKKATTDSESDKKAASSISSSNVVKQNSNKINLTNYKKIKV
  26 MKSKMKIIFSITMFFALVSVGVIKLNKENAAAYAAKGKALSHHMKNSVKDKKYSMKK------FL
  27 ------------------------TNSSKNDTKKESSEKKSEDKSKDNSDLKATYDKINVGDIMN
  28 ------------------------TNSSKNDTKKESSEKKSEDKSKDNSDLKATYDKINVGDIMN
  29 ------KIFGIFTTLFIVFFTCRTF---------------ATDLSTSYCTFNNCSPKQITYDNFL
  30 -----------------------------------------------------------------
  31 MIPLKKITVGTIVCLSFLGLTACSSSNTQQTSTSKSNVSQHKNIKADHEELRLKFNKVKLGVKAN
  32 -----------------------------------------------------------------
  33 -----------------------------------------------------------------
  34 -----------------------------------------------------------------
  35 -----------------------------------------------------------------
  36 -----------------------------------------------------------------
  37 -----------------------------------------------------------------
  38 -----------LGSAVALSLVACGDSTKEASNEKKEEP--KQEAKKENKENKESKKKITAADV-E
  39 -----------------------------------------------------------------
  40 -----------------------------------------------------------------
  41 -----------------------------------------------------------------
  42 -----------------------------------------------------------------
  43 ---------------------------------------RSELIAGEDYQFHITYDDIALLFADF
  44 --------------------------------------------KKENKENKESKKKITAADV-E
  45 -----------------------------------------------------------------
  46 -----------------------------------------------------------------


          70        80         90            100            110        
          |         |          |              |              |        
   1 HFSG.GTSIEQLKQWFG.DPNKSEQRNAGN.....ITLDSYTWVKDG.....AVINAQ.LYKNST
   2 NFKG.GTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRWNVDD.....ISITIQ.LLNDSS
   3 NFKG.GTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRWNVDD.....ISITIQ.LLNDSS
   4 SFTG.GTSLEELISLFG.EPNQHDPKTAGE.....VTIDAYTWQFDQ.....VTLTVN.LYQNSS
   5 SFTG.GTSLEELISLFG.EPNQHDPKTAGE.....VTIDAYTWQFDQ.....VTLTVN.LYQNSS
   6 SFTG.GTSLEELISLFG.EPSQHDPKTAGE.....VTIDAYTWQFDQ.....VTLTVN.LYQNSS
   7 SFTG.GTSLEELISLFG.EPSQHDPKTAGE.....VTIDAYTWQFDQ.....VTLTVN.LYQNSS
   8 SFTG.GTSLEELISLFG.EPSQHDPKTAGE.....VTINAYTWQFDQ.....VTLTVN.LYQNSS
   9 SFTG.GTSLEELISLFG.EPSQHDPKTAGE.....VTIDAYTWQFDQ.....VTLTVN.LYQNSS
  10 NFKG.GTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRWNVDD.....ISITIQ.LLNDSS
  11 HFSG.GTSIEQLKQWFG.DPNKSEQRNAGN.....ITLDSYTWVKDG.....AVINAQ.LYKNST
  12 KIKI.GSTYEEVKSILG.EYKESKESEING.....MKVVIYSWYNDDn....SNMEVI.VKNNKV
  13 KIKI.GSTYEEVKSILG.EYKESKESEING.....MKVVIYSWYNDDn....SNMEVI.VKNNKV
  14 KIKI.GSTYEEVKSILG.EYKESKESEIDG.....MKVVIYTWYNDDn....SNMEVI.VKNNKV
  15 KIKI.GSTYEEVKSILG.EYKESKESEIND.....MKVVIYSWYNDDn....SNMEVI.VKNNKV
  16 KIKI.GSTYEEVKSILG.EYKESKESEING.....MKVVIYTWYNDDn....SNMEVI.VKNNKV
  17 KVKM.GSTYEDVKNMLG.EAKESTSSEMGG.....IKTVIYTWDNGDg....SNMNVT.FQNNKA
  18 KVKM.GSTYEDVKNMLG.EGKESTSSEMGG.....IKTVIYTWDNGDg....SNMNVT.FQNNKA
  19 HGEG.GSTIQDVEKLLG.KANTTDTTTVES.....YKTKSYIWNKGA.....VTVTVQ.FEPDKV
  20 HGEG.GSTIQDVEKLLG.KANTTDTTTVDS.....YKTKSYIWNKGA.....VTVTVQ.FEPDKA
  21 NFKG.GTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRWNVDD.....ISITIQ.LLNDSS
  22 QGEG.GSTIDEVKQLLG.SPTSTTTTSSNG.....VKLKQLTWTKGA.....VTVAIQtLDSNKV
  23 NFKG.GTSLAELKQLFGgEPNEKFDTPAGN.....VTLKGYRWNVDD.....ISITIQ.LLNDSS
  24 VEKT.GSTPSQVTDLLG.READAKSKAKTSkl6tiYTWEGVQNGSAG.....ANLAVE.FANGVA
  25 VEKT.GSTPSQVTDLLG.READAKSKAKTSkl6tiYTWEGVQNGSAG.....ANLAVE.FANGVA
  26 RINM.GMNYKSVENILG.VSEKTGQINDKR.....ELMNHQWKNSDD.....SYIVVI.TKNNYV
  27 SSEG.GSTEDEVKAILG.EPASSSTTDIQG.....ISTTTLSWTNVKggdllASITVS.FSDGKA
  28 SSEG.GSTEDEVKAILG.EPASSSTTDIQG.....ISTTTLSWTNVKggdllASITVS.FSDGKA
  29 KVEI.GSNYNDVVKILG.KESYMDSAIING.....LKNTTYIWKINGte...KNIFIT.FRNGIV
  30 ----.GSTYEEVKNMLG.EGKESTSSEMGG.....IKTVIYTWDNGDg....SNMNVT.FQNNKA
  31 NFKG.GTSLAELTIIWW.RTNEX-LITAGN.....VTL---------.....------.------
  32 ----.------------.------------.....------------.....------.---GSL
  33 ----.------------.------------.....------------.....------.------
  34 ----.------------.------------.....------------.....------.------
  35 ----.------------.------------.....------------.....------.------
  36 ----.------------.------------.....------------.....------.------
  37 ----.------------.------------.....------------.....------.------
  38 AIKV.GDSLT-------.------------.....------------.....------.------
  39 ----.------------.------------.....------------.....------.------
  40 ----.------------.------------.....------------.....------.------
  41 ----.------------.------------.....------------.....------.------
  42 ----.------------.------------.....------------.....------.------
  43 KGTAsRLTADEVVAKLG.KAKSGREHNYDN.....QIITLNLDYPDAgsn..ASVSIS.FSSYGS
  44 AIKV.GDSLT-------.------------.....------------.....------.------
  45 ----.------------.------------.....------------.....------.------
  46 ----.------------.------------.....------------.....------.------


        120            130       140         150        160       170  
         |              |         |           |          |         |  
   1 VA..RSISNFSFS.....REAKIGKEDYDELKIGESY..KKVVEKLG.EPDVLSQSMSSDKEEMQ
   2 IV..RSISNFKFI.....RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
   3 IV..RSISNFKFI.....RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
   4 IV..KTISNFTFA.....RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   5 IV..KTISNFTFA.....RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   6 IV..KTISNFTFA.....RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   7 IV..KTISNFTFA.....RELGLSQKEYQQLQKGMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
   8 IV..KTISNFTFA.....RELGLSQKEYQQLQKGMSY..EDAKKILT.EPDNYSQASSSDHQTLQ
   9 IV..KTISNFTFA.....RELGLSQKEYQQLQKRMSY..EDVKKILT.EPDNYSQASSSDHQTLQ
  10 IV..RSISNFKFI.....RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
  11 VA..RSISNFSFS.....REAKIGKEDYDELKIGESY..KKVVEKLG.EPDVLSQSMSSDKEEMQ
  12 IG..KAQAGLSMG.....K-ADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  13 IG..KAQAGLSMG.....K-ADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  14 IG..KAQAGLSMG.....K-ADVNLIKYTKIRTGMDY..SKVKEILG.DGKLMSISKTNGSTKSI
  15 IG..KAQAGLSMG.....K-ADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  16 IG..KAQADLSMG.....K-ADVNLIKYAKITTGMDY..SKVEEILG.DGKLMSISKTNGSTKSI
  17 LA..KAQAGLSRK.....R-ADVNMEKYNKIQTGMDY..NKVKEILG.DGELMSISEVGGSNTSI
  18 LA..KAQAGLSRE.....K-ADVNMEKYNTIQTGMDY..NKIKEILG.AGELMSISEVGGSNTSI
  19 VT..KDITGFKWGk....RDEKLDLAAFNSIQDGASY..DDIVKKYG.EPDSLNESLLLGTKTVT
  20 VT..KDITGFKWGk....RDEKLDLAAFNSIQDGATY..DDIVKKYG.EPDSLNESLLLGTKTVT
  21 IV..RSISNFKFI.....RDANITTKDYNSLKNGMSY..NKVKELLG.EPDDISQAVSSDKEELQ
  22 VS..KEITGFKWGk....RDEKLTLGEFNNIADGSTY..QSLVDKYG.EPDGLHEANVAGTKITN
  23 IV..RSISNFKFI.....RDANITTKDYNSLKNXXSY..NKVKELLG.EPDDISQAV--------
  24 IA..KQISGLVVN.....RSKQITPKDYKSLKKGMTQ..EEVEAIVG.KPNGYSESDYSNSEVVL
  25 IA..KQISGLVVN.....RSKQITPKDYKSLKKGMTQ..EEVEAIVG.KPNGYSESDYSNSEVVL
  26 VS..KIEIGLE-K.....INANISRVKYKKISRGMSY..EKVKNLVG.KGELLSETNLMGSNSKM
  27 AS..KSVSGLKVA.....KHDKVTADQVNNIATDGSYseEQARKDLG.DPTGITSTNINGEKNDT
  28 AS..KSVSGLKVA.....KHDKVTADQVNNIATDGSYseEQARKDLG.DPTGITSTNINGEKNDT
  29 IT..KEQYKLN-D.....KFSILSNKKINSLKKGMSY..NEVKNILG.EGILRSE----EKETQV
  30 LA..KAQAGLSRE.....R-ADVNAEKYNRIQTGMDY..NKVKEILG.DGE--------------
  31 --..---------.....-------------------..--------.-----------------
  32 IF..ASLLLISCQ.....NKELVSQEKYKQLKLDMSY..EDVKKIMG.SPGKVKKFPGQPSTETT
  33 --..---------.....---------YEDLKNGTSY..DNAVKILG.VPDVYSIAVSSDATMTQ
  34 --..---------.....---------YEDLKNGTSY..DNAVKTLG.VPDVYSIAVSSDATMTQ
  35 --..---------.....---------YEDLKNGTSY..DNAVQTLG.VPDVYSIAVSSDATMTQ
  36 -A..IVLSAFLFG.....CFSKINQENYAKIENGMTM..EQVKDILG.EPTESQTAGIGSLSGTN
  37 --..---------.....----ITKENYDKVKNGMSY..EEVVKIIGsEGEIVTETGEKGDDMYG
  38 --..----G----.....-------------AGGEKY..EDVVAKFG.EPDNKAESQAGDIKMII
  39 --..---------.....---KLTTENYEKIKMGMDY..GEVAGILG.KPDSCSEALFAKS----
  40 --..---------.....---KLTMENYSKIKTGIGY..TEVVKILG.KPDNCSEALFV------
  41 --..---------.....---KLTQENYAKLKMGLGY..GEVVTILG.KPDSCSEALFAKSC---
  42 --..---------.....----VTVENYDKIRVGMTY..DEVKQLLG.APNRCSDVMTVKSCTW-
  43 VGtpKLDSLFSHHls8pnRNSQLTRQDFSGIEKGKSY..QEVVGQLG.LPDSLSIY---------
  44 --..----G----.....-------------AGGEKY..EDVVAKFG.EPDNKAESQAGDIKMII
  45 --..---------.....---KLTPENYDKLRMGMHY..AEVKSILG.EPTRCSDLLAVK----A
  46 --..---------.....-ENKVTRENYDKLAIGMEY..SKVVELLG.EPENCQSVVS-------


           180        190       200      
            |          |         |      
   1 TVWSSGIKTKSS.SATIELYFENGLLKNKTQKDLE
   2 AAWISGIQSSDS.DPGINLTFENDKLTNKQQHGL-
   3 AAWISGIQSSDS.DPGINLTFENDKLTNKQQHGL-
   4 AIWVSGLKTDTS.GANISLVFENNQLTEMSQVGLE
   5 AIWVSGLKTDTS.GANISLVFENNQLTEMSQVGLE
   6 AIWVSGLKTDTS.GANISLVFENNQLTEMSQVGLE
   7 AIWVSGLKTDTS.GANISLVFENNQLTEMSQVGLE
   8 AIWVSGLKTDTS.GANISLVFENNQLTEMSQVGLE
   9 AIWVSGLKTDTS.GANISLVFENNQLTEMSQVGLE
  10 AAWISGIQSSDS.DPGINLTFENDKLTNKQQHGL-
  11 TVWSSGIKTKSS.SATIELYFENGLLKNKTQKDLE
  12 YLWA-----NPN.GTNMNVTFQNGKVTAKNRLGL-
  13 YLWA-----NPN.GTNMNVTFQNGKVTAKNRLGL-
  14 YLWA-----NPN.GTNMNVTFQNGKVTTKNRLGL-
  15 YLWA-----NPN.GTNMNVTFQNGKVTAKNRLGL-
  16 YLWA-----NPN.GTNMNVTFQNGKVTAKNRLGL-
  17 YSWV-----NSN.GTNINVTFQDGKSAAKAQFGL-
  18 YSWV-----NSN.GTNMNVTFQDGKSAAKAQFGL-
  19 ALWYTGIKGKGA.GANASLTFENGALTSKTQTDL-
  20 GLWYTGIKGKAD.GAFASLTFENGALTSKTQTDL-
  21 AAWISGIQSSDS.DPGINLTFENDKLTNKQQHGL-
  22 AVWLTGIK-GDD.GASATFSFENDKLSSKTQTKL-
  23 ------------.----------------------
  24 WLYTSGLK-SDD.QANFYVTFQKNKLVAKKAQNF-
  25 WLYTSGLK-SDD.QANFYVTFQKNKLVAKKAQNF-
  26 YQWV-----NSD.GSSMNITFTNGIVDYKTEKKL-
  27 LIWMKNLD-GDL.GATVTVSFSNGSAISKSSSGL-
  28 LIWMKNLD-GDL.GATVTVSFSNGNAISKSSSGL-
  29 YSWF-----NND.SSYINCTFKNDKL---------
  30 ------------.----------------------
  31 ------------.----------------------
  32 YVWK----QKNS.SYRILVTLKDGKV---------
  33 ALWSSNLVTKKGkTGSLTLNFKNGTLENKSQENL-
  34 ALWSSNLVTKKGkTGSLTLNFKNGTLENKSQENL-
  35 ALWSSNLVTKKGkTGSLTLNFKNGTLENKSQENL-
  36 AIW------KSD.SVTIKLTFVNSKVQ--------
  37 IAVLYE-NKGSS.LSNATFIFLGDKLQSKSQYGLE
  38 ASWTKNVN-GDL.GANFNVTF--------------
  39 CIW------GNE.QKNITVNFVGDK----------
  40 ----RNCVWGNE.QKNITVSFVGDKAI--------
  41 -VW------GDE.QKNITVNFAGDRVV--------
  42 ---------GDE.KRHVQVSFVADQVV--------
  43 ------------.----------------------
  44 ASWTKNVN-GDL.GANFNVTF--------------
  45 CTW------GDD.ARYINVNFVADQAVLLN-----
  46 ------------.----------------------