PFRMAT SS TARGET T0395 AUTHOR 4008-1775-0004 METHOD This file is the result of combining several RDB files, specifically METHOD T0395.t06.str2.rdb (weight 1.54425) METHOD T0395.t06.str4.rdb (weight 0.924988) METHOD T0395.t06.pb.rdb (weight 0.789901) METHOD T0395.t06.bys.rdb (weight 0.748322) METHOD T0395.t06.alpha.rdb (weight 0.678173) METHOD T0395.t04.str2.rdb (weight 1.54425) METHOD T0395.t04.str4.rdb (weight 0.924988) METHOD T0395.t04.pb.rdb (weight 0.789901) METHOD T0395.t04.bys.rdb (weight 0.748322) METHOD T0395.t04.alpha.rdb (weight 0.678173) METHOD T0395.t2k.str2.rdb (weight 1.54425) METHOD T0395.t2k.str4.rdb (weight 0.924988) METHOD T0395.t2k.pb.rdb (weight 0.789901) METHOD T0395.t2k.bys.rdb (weight 0.748322) METHOD T0395.t2k.alpha.rdb (weight 0.678173) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0395.t06.str2.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3830 METHOD METHOD ============================================ METHOD Comments from T0395.t06.str4.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-str4-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 21 (1 str4 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3830 METHOD METHOD ============================================ METHOD Comments from T0395.t06.pb.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-pb-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 16 (1 pb ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3830 METHOD METHOD ============================================ METHOD Comments from T0395.t06.bys.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-bys-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 Bystroff ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3830 METHOD METHOD ============================================ METHOD Comments from T0395.t06.alpha.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t06-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t06-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 3830 METHOD METHOD ============================================ METHOD Comments from T0395.t04.str2.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1828 METHOD METHOD ============================================ METHOD Comments from T0395.t04.str4.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-str4-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 21 (1 str4 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1828 METHOD METHOD ============================================ METHOD Comments from T0395.t04.pb.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-pb-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 16 (1 pb ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1828 METHOD METHOD ============================================ METHOD Comments from T0395.t04.bys.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-bys-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 Bystroff ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1828 METHOD METHOD ============================================ METHOD Comments from T0395.t04.alpha.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t04-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t04-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 1828 METHOD METHOD ============================================ METHOD Comments from T0395.t2k.str2.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-str2-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 13 (1 str2 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 268 METHOD METHOD ============================================ METHOD Comments from T0395.t2k.str4.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-str4-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 21 (1 str4 ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 268 METHOD METHOD ============================================ METHOD Comments from T0395.t2k.pb.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-pb-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 16 (1 pb ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 268 METHOD METHOD ============================================ METHOD Comments from T0395.t2k.bys.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-bys-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 Bystroff ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 268 METHOD METHOD ============================================ METHOD Comments from T0395.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0395 METHOD Using neural net dunbrack-40pc-3157-t2k-IDGaaH13-3-13-7-13-9-13-11-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 3 13 METHOD 7 13 METHOD 9 13 METHOD 11 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0395.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(1.3 bits/column, 1) METHOD The weighting was determined by the posterior distribution METHOD after regularizing with /projects/compbio/lib/recode3.20comp. METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 268 METHOD METHOD ============================================ MODEL 1 M C 0.58 R C 0.59 L C 0.60 G C 0.67 D C 0.60 A H 0.54 A H 0.61 E H 0.53 L H 0.47 C H 0.44 Y H 0.50 N C 0.46 L C 0.57 T C 0.63 S C 0.55 S C 0.48 Y H 0.53 L H 0.62 Q H 0.61 I H 0.52 A H 0.47 A H 0.50 E H 0.47 S H 0.50 D H 0.62 S H 0.78 I H 0.86 I H 0.90 A H 0.89 Q H 0.88 T H 0.89 Q H 0.91 R H 0.91 A H 0.90 I H 0.90 N H 0.88 T H 0.85 T H 0.83 K H 0.84 S H 0.82 I H 0.81 L H 0.81 I H 0.82 N H 0.79 E H 0.73 T H 0.60 F H 0.49 P H 0.66 K H 0.58 W C 0.43 S C 0.57 P C 0.56 L C 0.63 N C 0.73 G C 0.75 E C 0.55 I E 0.69 S E 0.77 F E 0.80 S E 0.76 Y E 0.59 N C 0.61 G C 0.76 G C 0.74 K C 0.54 D H 0.51 C H 0.73 Q H 0.82 V H 0.88 L H 0.92 L H 0.92 L H 0.92 L H 0.92 Y H 0.92 L H 0.90 S H 0.85 C H 0.71 L H 0.47 W C 0.53 E C 0.67 Y C 0.64 Y C 0.49 I E 0.70 V E 0.77 K E 0.75 L E 0.64 S C 0.58 Q C 0.64 S C 0.65 Q C 0.64 F C 0.63 D C 0.72 G C 0.49 K C 0.49 F C 0.45 H C 0.46 R C 0.48 F C 0.62 P C 0.48 L H 0.48 T C 0.44 K C 0.53 L C 0.58 P C 0.56 T C 0.51 V C 0.51 F E 0.48 I E 0.48 D C 0.59 H C 0.55 D C 0.54 D C 0.57 T C 0.56 F C 0.59 K C 0.46 T C 0.45 L H 0.72 E H 0.83 N H 0.87 F H 0.89 I H 0.90 E H 0.91 E H 0.90 T H 0.86 S H 0.82 L H 0.75 R H 0.57 Y C 0.52 S C 0.65 L C 0.56 S C 0.55 L C 0.47 Y C 0.51 E C 0.50 S C 0.52 D C 0.62 R C 0.63 D C 0.54 K C 0.46 C H 0.43 E H 0.44 T H 0.51 M H 0.67 A H 0.81 E H 0.84 A H 0.80 F H 0.81 E H 0.84 T H 0.89 F H 0.86 L H 0.89 Q H 0.81 V H 0.63 F C 0.55 P C 0.56 E C 0.73 T C 0.66 K E 0.49 A E 0.77 I E 0.79 V E 0.78 I E 0.74 G E 0.65 I E 0.56 R C 0.51 H C 0.54 T C 0.62 D C 0.69 P C 0.59 F C 0.56 G C 0.53 E C 0.44 H C 0.52 L C 0.60 K C 0.62 P C 0.60 I C 0.51 Q C 0.49 K C 0.49 T C 0.60 D C 0.72 A C 0.56 N C 0.67 W C 0.70 P C 0.57 D C 0.50 F C 0.37 Y E 0.54 R E 0.61 L E 0.59 Q E 0.48 P C 0.48 L C 0.47 L C 0.43 H C 0.48 W C 0.49 N C 0.62 L H 0.73 A H 0.85 N H 0.91 I H 0.90 W H 0.92 S H 0.92 F H 0.92 L H 0.92 L H 0.88 Y H 0.79 S C 0.63 N C 0.87 E C 0.78 P C 0.67 I C 0.49 C C 0.50 E H 0.61 L H 0.63 Y H 0.61 R H 0.48 Y C 0.71 G C 0.83 F C 0.65 T C 0.55 S C 0.54 L C 0.55 G C 0.66 N C 0.65 V C 0.59 E C 0.56 E C 0.62 T C 0.64 L C 0.67 P C 0.68 N C 0.74 P H 0.48 H C 0.47 L C 0.46 R C 0.58 K C 0.59 D C 0.69 K C 0.62 N C 0.66 S C 0.64 T C 0.70 P C 0.59 L C 0.52 K C 0.46 L C 0.46 N C 0.48 F C 0.42 E H 0.38 W H 0.44 E H 0.49 I H 0.55 E H 0.57 N H 0.48 R C 0.47 Y C 0.51 K C 0.55 H C 0.57 N C 0.63 E C 0.51 V C 0.50 T C 0.53 K C 0.52 A C 0.58 E C 0.66 P C 0.66 I C 0.65 P C 0.59 I C 0.51 A C 0.55 D C 0.54 E H 0.57 D H 0.51 L H 0.48 V H 0.45 K H 0.46 I H 0.56 E H 0.56 N C 0.44 L C 0.49 H C 0.54 E H 0.47 D C 0.56 Y C 0.63 Y C 0.69 P C 0.59 G C 0.58 W E 0.42 Y E 0.56 L E 0.55 V C 0.46 D C 0.58 D H 0.49 K H 0.58 L H 0.65 E H 0.69 R H 0.53 A C 0.49 G C 0.62 R C 0.57 I C 0.53 K C 0.49 K C 0.53 K C 0.55 END