a2m2html output for tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0361 A putative transcriptional regulator, Shigella flexneri 2a str. 2457T, 169 res
- gi|82545446|ref|YP_409393.1|_1:169 putative transcriptional regulator [Shigella boydii Sb227]
- gi|81246857|gb|ABB67565.1| putative transcriptional regulator [Shigella boydii Sb227]
- gi|75258533|ref|ZP_00729955.1|_1:169 COG3722: Transcriptional regulator [Escherichia coli E22]
- gi|75228601|ref|ZP_00715230.1| COG3722: Transcriptional regulator [Escherichia coli B7A]
- gi|75212453|ref|ZP_00712477.1| COG3722: Transcriptional regulator [Escherichia coli B171]
- gi|83587671|ref|ZP_00926298.1|_1:169 COG3722: Transcriptional regulator [Escherichia coli 101-1]
- gi|75515287|ref|ZP_00737471.1|_1:169 COG3722: Transcriptional regulator [Escherichia coli 53638]
- gi|75196880|ref|ZP_00706950.1| COG3722: Transcriptional regulator [Escherichia coli HS]
- gi|16130830|ref|NP_417404.1|_1:169 predicted DNA-binding transcriptional regulator [Escherichia coli K12]
- gi|1789297|gb|AAC75966.1| predicted DNA-binding transcriptional regulator [Escherichia coli K12]
- gi|89109707|ref|AP_003487.1| predicted DNA-binding transcriptional regulator [Escherichia coli W3110]
- gi|1723852|sp|P11663|YGGD_ECOLI Hypothetical protein yggD [Taxonomy]
- gi|85675740|dbj|BAE76993.1| predicted DNA-binding transcriptional regulator [Escherichia coli W3110]
- gi|882458|gb|AAA69096.1| ORF_f169; alternate name yggD; orf2 of X14436 [Taxonomy]
- gi|75239498|ref|ZP_00723469.1|_1:169 COG3722: Transcriptional regulator [Escherichia coli E110019]
- gi|75187649|ref|ZP_00700916.1| COG3722: Transcriptional regulator [Escherichia coli E24377A]
- gi|26109755|gb|AAN81960.1|_1:169 Hypothetical protein yggD [Escherichia coli CFT073]
- gi|26249347|ref|NP_755387.1| Hypothetical protein yggD [Escherichia coli CFT073]
- gi|24053327|gb|AAN44400.1|_1:169 putative transcriptional regulator [Shigella flexneri 2a str. 301]
- gi|24114183|ref|NP_708693.1| putative transcriptional regulator [Shigella flexneri 2a str. 301]
- gi|30042499|gb|AAP18223.1| putative transcriptional regulator [Shigella flexneri 2a str. 2457T]
- gi|30064242|ref|NP_838413.1| putative transcriptional regulator [Shigella flexneri 2a str. 2457T]
- gi|82778302|ref|YP_404651.1|_1:169 putative transcriptional regulator [Shigella dysenteriae Sd197]
- gi|81242450|gb|ABB63160.1| putative transcriptional regulator [Shigella dysenteriae Sd197]
- gi|91212310|ref|YP_542296.1|_1:169 putative transcriptional regulator [Escherichia coli UTI89]
- gi|91073884|gb|ABE08765.1| putative transcriptional regulator [Escherichia coli UTI89]
- gi|75241273|ref|ZP_00725135.1|_1:169 COG3722: Transcriptional regulator [Escherichia coli F11]
- gi|15803468|ref|NP_289501.1|_1:169 putative transcriptional regulator [Escherichia coli O157:H7 EDL933]
- gi|15833059|ref|NP_311832.1| putative transcriptional regulator [Escherichia coli O157:H7 str. Sakai]
- gi|13363277|dbj|BAB37228.1| putative transcriptional regulator [Escherichia coli O157:H7 str. Sakai]
- gi|12517469|gb|AAG58060.1| putative transcriptional regulator [Escherichia coli O157:H7 EDL933]
- gi|77978092|ref|ZP_00833526.1|_4:172 COG3722: Transcriptional regulator [Yersinia intermedia ATCC 29909]
- gi|77960732|ref|ZP_00824591.1|_4:172 COG3722: Transcriptional regulator [Yersinia mollaretii ATCC 43969]
- gi|77973742|ref|ZP_00829287.1|_4:172 COG3722: Transcriptional regulator [Yersinia frederiksenii ATCC 33641]
- gi|77959633|ref|ZP_00823651.1|_4:172 COG3722: Transcriptional regulator [Yersinia bercovieri ATCC 43970]
- gi|15804142|ref|NP_290181.1|_22:189 repressor for mtl [Escherichia coli O157:H7 EDL933]
- gi|15833731|ref|NP_312504.1| repressor for mtl [Escherichia coli O157:H7 str. Sakai]
- gi|74314165|ref|YP_312584.1| repressor for mtl [Shigella sonnei Ss046]
- gi|13363952|dbj|BAB37900.1| repressor for mtl [Escherichia coli O157:H7 str. Sakai]
- gi|12518345|gb|AAG58745.1| repressor for mtl [Escherichia coli O157:H7 EDL933]
- gi|75255817|ref|ZP_00727563.1| COG3722: Transcriptional regulator [Escherichia coli E22]
- gi|75237541|ref|ZP_00721574.1| COG3722: Transcriptional regulator [Escherichia coli E110019]
- gi|75228664|ref|ZP_00715285.1| COG3722: Transcriptional regulator [Escherichia coli B7A]
- gi|75211356|ref|ZP_00711455.1| COG3722: Transcriptional regulator [Escherichia coli B171]
- gi|75188364|ref|ZP_00701631.1| COG3722: Transcriptional regulator [Escherichia coli E24377A]
- gi|83571591|ref|ZP_00923031.1| COG3722: Transcriptional regulator [Shigella dysenteriae 1012]
- gi|73857642|gb|AAZ90349.1| repressor for mtl [Shigella sonnei Ss046]
- gi|16131472|ref|NP_418058.1|_22:189 DNA-binding repressor [Escherichia coli K12]
- gi|1790029|gb|AAC76625.1| DNA-binding repressor [Escherichia coli K12]
- gi|26110669|gb|AAN82854.1| Mannitol operon repressor [Escherichia coli CFT073]
- gi|91213112|ref|YP_543098.1| mannitol operon repressor [Escherichia coli UTI89]
- gi|91074686|gb|ABE09567.1| mannitol operon repressor [Escherichia coli UTI89]
- gi|26250240|ref|NP_756280.1| Mannitol operon repressor [Escherichia coli CFT073]
- gi|89110411|ref|AP_004191.1| DNA-binding transcriptional repressor [Escherichia coli W3110]
- gi|82545961|ref|YP_409908.1| repressor for mtl [Shigella boydii Sb227]
- gi|466739|gb|AAB18578.1| mtlR [Escherichia coli]
- gi|84028152|sp|P0AF10|MTLR_ECOLI Mannitol operon repressor (Mannitol repressor protein) [Taxonomy]
- gi|85676442|dbj|BAE77692.1| DNA-binding transcriptional repressor [Escherichia coli W3110]
- gi|84028151|sp|P0AF11|MTLR_ECOL6 Mannitol operon repressor (Mannitol repressor protein) [Taxonomy]
- gi|434583|gb|AAA92662.1| mannitol repressor [Taxonomy]
- gi|75514332|ref|ZP_00736640.1| COG3722: Transcriptional regulator [Escherichia coli 53638]
- gi|75242616|ref|ZP_00726360.1| COG3722: Transcriptional regulator [Escherichia coli F11]
- gi|75197508|ref|ZP_00707578.1| COG3722: Transcriptional regulator [Escherichia coli HS]
- gi|75179768|ref|ZP_00699755.1| COG3722: Transcriptional regulator [Shigella boydii BS512]
- gi|83588547|ref|ZP_00927171.1| COG3722: Transcriptional regulator [Escherichia coli 101-1]
- gi|81247372|gb|ABB68080.1| repressor for mtl [Shigella boydii Sb227]
- gi|45438571|gb|AAS64117.1|_4:172 mannitol operon repressor [Yersinia pestis biovar Medievalis str. 91001]
- gi|108809007|ref|YP_652923.1| mannitol operon repressor [Yersinia pestis Antiqua]
- gi|108813873|ref|YP_649640.1| mannitol operon repressor [Yersinia pestis Nepal516]
- gi|108780920|gb|ABG14978.1| mannitol operon repressor [Yersinia pestis Antiqua]
- gi|108777521|gb|ABG20040.1| mannitol operon repressor [Yersinia pestis Nepal516]
- gi|21961097|gb|AAM87628.1| repressor for mtl [Yersinia pestis KIM]
- gi|51591487|emb|CAH23158.1| mannitol operon repressor [Yersinia pseudotuberculosis IP 32953]
- gi|15981961|emb|CAC93520.1| mannitol operon repressor [Yersinia pestis CO92]
- gi|22127954|ref|NP_671377.1| repressor for mtl [Yersinia pestis KIM]
- gi|51598205|ref|YP_072396.1| mannitol operon repressor [Yersinia pseudotuberculosis IP 32953]
- gi|45443701|ref|NP_995240.1| mannitol operon repressor [Yersinia pestis biovar Medievalis str. 91001]
- gi|16124180|ref|NP_407493.1| mannitol operon repressor [Yersinia pestis CO92]
- gi|89105246|ref|ZP_01177769.1| COG3722: Transcriptional regulator [Yersinia pestis biovar Orientalis str. IP275]
- gi|77634204|ref|ZP_00796310.1| COG3722: Transcriptional regulator [Yersinia pestis Angola]
- gi|77630984|ref|ZP_00793570.1| COG3722: Transcriptional regulator [Yersinia pseudotuberculosis IP 31758]
- gi|27360216|gb|AAO09153.1|_1:172 Mannitol operon repressor [Vibrio vulnificus CMCP6]
- gi|27364098|ref|NP_759626.1| Mannitol operon repressor [Vibrio vulnificus CMCP6]
- gi|24054101|gb|AAN45082.1|_22:189 repressor for mtl [Shigella flexneri 2a str. 301]
- gi|24114865|ref|NP_709375.1| repressor for mtl [Shigella flexneri 2a str. 301]
- gi|30043386|gb|AAP19107.1| repressor for mtl [Shigella flexneri 2a str. 2457T]
- gi|30065125|ref|NP_839296.1| repressor for mtl [Shigella flexneri 2a str. 2457T]
- gi|28805351|dbj|BAC58631.1|_1:172 mannitol operon repressor [Vibrio parahaemolyticus RIMD 2210633]
- gi|28897142|ref|NP_796747.1| mannitol operon repressor [Vibrio parahaemolyticus RIMD 2210633]
- gi|75854725|ref|ZP_00762401.1|_1:172 COG3722: Transcriptional regulator [Vibrio sp. Ex25]
- gi|91227137|ref|ZP_01261621.1|_1:172 mannitol operon repressor [Vibrio alginolyticus 12G01]
- gi|91188789|gb|EAS75076.1| mannitol operon repressor [Vibrio alginolyticus 12G01]
- gi|37197427|dbj|BAC93267.1|_5:176 mannitol operon repressor [Vibrio vulnificus YJ016]
- gi|37678687|ref|NP_933296.1| mannitol operon repressor [Vibrio vulnificus YJ016]
- gi|62182181|ref|YP_218598.1|_23:190 repressor for mtl [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
- gi|62129814|gb|AAX67517.1| repressor for mtl [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
- gi|16766972|ref|NP_462587.1|_23:190 mannitol operon repressor [Salmonella typhimurium LT2]
- gi|16762622|ref|NP_458239.1| mannitol operon repressor (mannitol repressor protein) [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
- gi|29144111|ref|NP_807453.1| mannitol operon repressor [Salmonella enterica subsp. enterica serovar Typhi Ty2]
- gi|16422253|gb|AAL22546.1| repressor for mtl [Salmonella typhimurium LT2]
- gi|16504927|emb|CAD03307.1| mannitol operon repressor (mannitol repressor protein) [Salmonella enterica subsp. enterica serovar Typhi]
- gi|29139748|gb|AAO71313.1| mannitol operon repressor [Salmonella enterica subsp. enterica serovar Typhi Ty2]
- gi|25513043|pir||AG0976 mannitol operon repressor (mannitol repressor protein) [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) [Taxonomy]
- gi|5566392|gb|AAD45387.1|_22:189 mtl operon repressor [Klebsiella pneumoniae]
- gi|90411409|ref|ZP_01219420.1|_1:172 putative mannitol operon repressor [Photobacterium profundum 3TCK]
- gi|90327622|gb|EAS43965.1| putative mannitol operon repressor [Photobacterium profundum 3TCK]
- gi|54302041|ref|YP_132034.1|_1:172 putative mannitol operon repressor [Photobacterium profundum SS9]
- gi|46915462|emb|CAG22234.1| putative mannitol operon repressor [Photobacterium profundum SS9]
- gi|75178830|ref|ZP_00698866.1|_1:147 COG3722: Transcriptional regulator [Shigella boydii BS512]
- gi|75831881|ref|ZP_00761141.1|_1:172 COG3722: Transcriptional regulator [Vibrio cholerae MO10]
- gi|75825111|ref|ZP_00754547.1| COG3722: Transcriptional regulator [Vibrio cholerae O395]
- gi|75820767|ref|ZP_00750807.1| COG3722: Transcriptional regulator [Vibrio cholerae V51]
- gi|75816617|ref|ZP_00747082.1| COG3722: Transcriptional regulator [Vibrio cholerae V52]
- gi|9658491|gb|AAF96941.1|_18:189 mannitol operon repressor [Vibrio cholerae O1 biovar eltor str. N16961]
- gi|15601798|ref|NP_233429.1| mannitol operon repressor [Vibrio cholerae O1 biovar eltor str. N16961]
- gi|84778514|dbj|BAE73291.1|_31:198 mannitol operon repressor [Sodalis glossinidius str. 'morsitans']
- gi|85057994|ref|YP_453696.1| mannitol operon repressor [Sodalis glossinidius str. 'morsitans']
- gi|49609576|emb|CAG73009.1|_26:196 mannitol operon repressor [Erwinia carotovora subsp. atroseptica SCRI1043]
- gi|50119050|ref|YP_048217.1| mannitol operon repressor [Erwinia carotovora subsp. atroseptica SCRI1043]
- gi|12721399|gb|AAK03147.1|_1:168 Mtl [Pasteurella multocida subsp. multocida str. Pm70]
- gi|15602928|ref|NP_246000.1| Mtl [Pasteurella multocida subsp. multocida str. Pm70]
- gi|77972604|ref|ZP_00828166.1|_1:169 COG3722: Transcriptional regulator [Yersinia frederiksenii ATCC 33641]
- gi|52306516|gb|AAU37016.1|_1:168 unknown [Mannheimia succiniciproducens MBEL55E]
- gi|52424464|ref|YP_087601.1| hypothetical protein MS0409 [Mannheimia succiniciproducens MBEL55E]
- gi|41419|emb|CAA32601.1|_1:133 unnamed protein product [Escherichia coli]
- gi|46156275|ref|ZP_00133149.2|_1:167 COG3722: Transcriptional regulator [Haemophilus somnus 2336]
- gi|53692704|ref|ZP_00347400.1|_1:167 COG3722: Transcriptional regulator [Haemophilus somnus 129PT]
- gi|106882917|ref|ZP_01350317.1|_4:174 Mannitol repressor [Psychromonas ingrahamii 37]
- gi|106761892|gb|EAT18776.1| Mannitol repressor [Psychromonas ingrahamii 37]
- gi|106883861|ref|ZP_01351253.1|_4:174 Mannitol repressor [Psychromonas ingrahamii 37]
- gi|106761070|gb|EAT17962.1| Mannitol repressor [Psychromonas ingrahamii 37]
- gi|75855358|ref|ZP_00763011.1|_1:168 COG3722: Transcriptional regulator [Vibrio sp. Ex25]
- gi|28808669|dbj|BAC61846.1|_1:168 putative transcriptional regulator [Vibrio parahaemolyticus RIMD 2210633]
- gi|28900358|ref|NP_800013.1| putative transcriptional regulator [Vibrio parahaemolyticus RIMD 2210633]
- gi|86144868|ref|ZP_01063200.1|_21:190 putative mannitol operon repressor [Vibrio sp. MED222]
- gi|85837767|gb|EAQ55879.1| putative mannitol operon repressor [Vibrio sp. MED222]
- gi|59713246|ref|YP_206021.1|_1:168 transcriptional regulator [Vibrio fischeri ES114]
- gi|59481494|gb|AAW87133.1| transcriptional regulator [Vibrio fischeri ES114]
- gi|84386268|ref|ZP_00989297.1|_21:190 putative mannitol operon repressor [Vibrio splendidus 12B01]
- gi|84379038|gb|EAP95892.1| putative mannitol operon repressor [Vibrio splendidus 12B01]
- gi|53729271|ref|ZP_00348358.1|_1:170 COG3722: Transcriptional regulator [Actinobacillus pleuropneumoniae serovar 1 str. 4074]

                             10        20        30        40        50
                             |         |         |         |         |
   1 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
   2 ....M...A..K...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
   3 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
   4 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
   5 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVDNDEEIV
   6 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVDNDEEIV
   7 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
   8 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGICQFLPSLFVDNDEEIV
   9 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
  10 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMNTAHSILLQGIRQFLPSLFVDNDEEIV
  11 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
  12 ....M...A..T...L..TED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIV
  13 ....M...A..T...L..SED.DVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEESV
  14 ....MiekT..Q...A..FEN.RVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVF-RKDDYAV
  15 ....MiekT..Q...A..FEN.RVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVF-RKDDYAV
  16 ....MiekT..Q...A..FEN.RVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVF-RKDDYAV
  17 ....MiekT..Q...A..FEN.RVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVF-RKDDYAV
  18 qat.M...E..Q...TqaFEN.RVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVF-RKDDYAV
  19 qat.M...E..Q...TqaFEN.RVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVF-RKDDYAV
  20 ....MiekK..Q...A..FEN.RVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIF-RKDDYAV
  21 m...A...E..H...T..NES.DIIERLNHAPSVRGFFVETVDILTEAVDGLVQRIF-RKDNFAV
  22 qat.M...E..Q...TqaVEN.RVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVF-RKDDYAV
  23 m...A...D..N...I..NES.EIIERLNSAPSVRGFFIATVDVFNESIDGLIQRIF-RKDNFAV
  24 m...A...D..N...I..NET.EIIERLNSAPSVRGFFIAAVDVFNDSIDGLIQRIF-RKDNFAV
  25 m...A...D..N...I..NET.EIIERLNSAPSVRGFFIAAVDVFNDSIDGLVQRIF-RKDNFAV
  26 iqfmA...E..H...T..NES.DIIERLNHAPSVRGFFVETVDILTEAVDGLVQRIF-RKDNFAV
  27 qai.M...E..Q...TqaFEN.RVLERLNAGKTVRSFLITAVELLTEAVNILVLQVF-RKDDYAV
  28 qai.M...E..Q...TqaFEN.RVLERLNAGKTVRSFLITAVELLTEAVNILVLQVF-RKDDYAV
  29 qa..MmeeT..Q...A..FEN.RVLERLNAGKTVRSFLIATVELLTEAVNILVLQVF-RKDDYAV
  30 ....M...A..Q...Sd.QES.DILERLSDTSNVRGFIITSVEVFEEAVDSLIQRVF-RKDDFAV
  31 ....M...A..Q...Sd.QES.DILERLSDTSNVRGFIITSVEVFEEAVDSLIQRIF-RKDDFAV
  32 ....-...-..-...-..---.---------------MKTAHSILLQGIRQFLPSLFVDNDEEIV
  33 m...A...E..K...I..NES.DILERLNQTHTVRGFFITTVDVLTEAIDALMQRIF-RKDNFAV
  34 dqfmA...E..K...I..NES.DILERLNQTHTVRGFFITTVDVLTEAIDALMQRIF-RKDNFAV
  35 ....MtenT..Q...L..LEN.SVLERLNAGTTVREFLRAAITLLAEAVAILVTQVF-RKDDYAV
  36 evt.M...EetQ...A..FEN.RVLEALNSGKTVRDFMLCAVELLAEAASILMLQVF-RKDDYAV
  37 ....M...Q..S...V..--D.PIYEKLNEATSIRGFITASVAIFDEAVDKLINRVF-RKTDFAV
  38 ....M...T..A...L..TED.DVLERLASPENLNDFLLNANEILFQGIKSLLPYLFINNDEDIQ
  39 ....M...T..S...-..-ED.PIYEKLNETTSIRGFITACVAIFDESVDQLINRVF-RKTDFAV
  40 ....-...-..-...-..---.---------------MKTAHTILLQGIRQFLPSLFVDNDEEIV
  41 ....M...-..-...L..SED.PIYEKLNSTVSVRGFMIATVAIFEEAVDSLINRVF-RKTDFVV
  42 ....M...-..-...L..SED.PIYEKLNGTVSVRGFMIAIVAIFEEAVDSLINRVF-RKTDFVV
  43 ....MptfS..R...L..KFDiDIVETLSEAETAYVFFTASFDLFEDAIDILIQNVF-RKDDYAV
  44 ....M...T..KfarL..KFDiDIVETLSEAETPYDFFTASFDLFEDAVDILIQNVF-RKDDYAV
  45 ....M...S..R...-..-ED.ELLEKLDECENATAFLQVSNKIINLKLKALLPSVFVQ-DDLVK
  46 ....M...S..R...-..-ED.ELLEKLDECENATAFLQVSNKIINLKLKALLPSVFVQ-DDLVK
  47 tmp.I...H..T...T..HES.ELLEELAESADAAECLLCAYDVLEDMLDALLKSIF-YKDDYAV
  48 ....M...S..Q...H..VE-.-LLETVEECDDATSFLCASNKLINLKLKALLPNIFVQ-DELVM
  49 vmp.I...Q..T...S..HET.ELLEALSEAESASACLMAAYDALDDTVDAVLKNIF-KKDDTAI
  50 ....M...P..-...-..YSD.NFIEQLSEVPSLRGFFALSVNQFAQNIERLIQRVF-RKTDFAL


              60        70        80        90       100        110    
              |         |         |         |         |          |    
   1 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFAD.DITWD
   2 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
   3 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
   4 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
   5 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
   6 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
   7 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFAD.DMTWD
   8 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DITWD
   9 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFAD.DITWD
  10 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
  11 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMAWD
  12 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQNEMPGFAD.DMAWD
  13 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLKEQDETLGFAD.DMTWD
  14 KYAVEPLLVGDGPLGELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTD.DEILG
  15 KYAVEPLLVGDGPLGELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTD.DEILG
  16 KYAVEPLLVGDGPLGELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTD.DEILG
  17 KYAVEPLLVGDGPLGELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTD.DEILG
  18 KYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTD.DEILG
  19 KYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTD.DEILG
  20 KYAVEPLLVGDGPLSELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTD.DEILG
  21 QSVVGPLLQDSGPLGDVSVRLKLLFGLGVLSDHHYHDIEDIIKLKNKLNSDSTEYEFTD.PQILE
  22 KYAVEPLLDGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTD.DEILG
  23 QSVVGPLLQDSGPLGDLSVRLKLLFGLGVLPDDIYHDIEDIIKLKNHLNSDASDYEFTD.PNILE
  24 QSVVGPLLQDSGPLGDLSVRLKLLFGLGVLPDDIYHDIEDIIKLKNRLNSDASDYEFTD.PNILE
  25 QSVVGPLLQDSGPLGDLSVRLKLLFGLGVLPDDIYHDIEDIIKLKNQLNSDASDYEFTD.PNILE
  26 QSVVGPLLQDSGPLGDVSVRLKLLFGLGVLSDHHYHDIEDIIKLKNKLNSDSTEYEFTD.PQILE
  27 KYAVEPLLDGDGPLGDLSVRLKLIYGLGVLSRTEYEDAELLMALREELNHDGNEYAFTD.DEILG
  28 KYAVEPLLDGDGPLGDLSVRLKLIYGLGVLSRTEYEDAELLMALREELNHDGNEYAFTD.DEILG
  29 KYAVEPLLEGSGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREELNHDGNEYSFTD.DEIIG
  30 KSVVGPLLDNSGPLGEITVRLKLLLGLGVVSHNIYQDIDAFLKLRDFLNSDGNDYCFTD.PKILQ
  31 KSVVGPLLDNSGPLGEITVRLKLLLGLGVVSHNIYQDIDAFLKLRDFLNSDGSDYCFTD.PKILQ
  32 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
  33 KSVVEPLLHDTGPLGDLTVRLKLLFGLGVIPDEVFHDIEHLIKLRNQLNHDATEYQFTD.PQILA
  34 KSVVEPLLHDTGPLGDLTVRLKLLFGLGVIPDEVFHDIEHLIKLRNQLNHDATEYQFTD.PQILA
  35 KYAVEPLLVGAGPLVELSVRLKLVYALGVISRQEYEDAELLMALHEELKQDPGDYRFTD.DEILG
  36 KYAVEPLMTGTGPLGDLSVRLKLIYGLGMISRKEYEDAELLMALGEELAHDDRHYRFTD.DEILG
  37 KSVVDSLLSNSGPLCDLSIRLKVLLGLGIIEHHVFSDISHFIEIKEKLNNDEKEYDFAD.LIIID
  38 EYAVKPLLAKSGPLDSLDVSLRLIYALGQITKAVYADILLFSQLSEHLQETGEIAEFHD.DIVYE
  39 KSVVDSLFINSGPLFDLSIRLKVLLGLGIISHETFMDINAFIQLKEALNNDGKEYEFFD.PIIIS
  40 EYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFAD.DMTWD
  41 QSVIDSLFTNDGPLGDLSVRLKVLLGLGVIQHNLFSDVNAFIQFKETLNKDEKEYTFDD.EIVLT
  42 QSVIDSLFTNDGPLGDLSVRLKVLLGLGVIQHNLFSDVNAFIQFKETLNKDEKEYTFDD.EIVLT
  43 KYAVEPLLNNDGPLAQLAIRIKLLYGLGLLSQDAYQDIEKFIALKTFVQSEGESIDFLS.PLLFE
  44 KYAVEPLLSRDGPLAHLPVRIKLLYGLGLLSQGSYQDIEKFIGLKEFVQSEGESIEFLS.LALIE
  45 EYAVDPLLKEDGPLVTTDVVSKLMFAMGKISLETYADIGLYDQVLEYVVSQPEKVEFAD.DVIYD
  46 EYAVDPLLREDGPLVTTDVVSKLMFAMGKISLQTYADIGLYDQVLEYVVTQPEKIAFTD.DVIYD
  47 KFVVDPLLTTDGPLGEILVRTKLLLGLGVISKEVYDDIEVFVTLKEWVNIQEGQVNFWDqDVVFE
  48 EYAVEPLLKEDGPLVTTDVVSKLMFAMGKISLETYADIGLYAQVLEYAQSQPNKLSFGD.DMIYD
  49 KFVVEPLLNSGGPLGEIMIRAKLLLGLGVISKELYDDLEIFVTLKEWAKIQGEDTSFTEvDVIFE
  50 KSVVDSLFEHQGPLAELTVRLKLLLGLGVISAAVFEDISLFIEVKQQLSDEVEELPFSH.PAIVQ


           120            130                    140        150       1
            |              |                      |          |        
   1 FISN..VNSITR.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   2 FISN..VNSITR.N.AML...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   3 FISN..VNSITC.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   4 FISN..VNSITR.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   5 FISN..VNSITC.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   6 FISN..VNSITR.N.AML...YD..A.LK.....AMK.FA..D..FS.VWSEARFSGMVKTALTL
   7 FISN..VNSITC.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   8 FISN..VNSITR.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
   9 FISN..VNSITR.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
  10 FISN..VNSITC.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
  11 FISN..VNSIIR.N.ASL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALML
  12 FISN..VNSITR.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
  13 FISN..VNSITC.N.ATL...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
  14 PFGE..LHCVAE.L.PPV...PT..F.LR.....PDEaDA..S..LI.AMQRQRYQQMVRSTMVL
  15 PFGE..LHCVAE.L.PPV...PT..F.LR.....PDEaDA..S..LI.AMQRQRYQQMVRSTMVL
  16 PFGE..LHCVAE.L.PPA...PT..F.LR.....PDEaDA..S..LI.AMQRQRYQQMVRSTMVL
  17 PFGE..LHCVVE.L.PPV...PT..F.LR.....PDEaDA..S..LI.AMQRQRYQQMVRSTMVL
  18 PFGE..LHCVAA.L.PPP...PQ..F.--.....EPA.DS..S..LY.AMQIQRYQQAVRSTMVL
  19 PFGE..LHCVAA.L.PPP...PQ..F.--.....EPA.DS..S..LY.AMQIQRYQQAVRSTMVL
  20 PFGE..LHCVDE.L.PPV...PT..F.LR.....PDEaDA..S..LI.AMQRQRYQQMVRSTMVL
  21 PIKK..LHLVQK.M.GMVq..LE..V.DD.....PDD.DIelS..FY.QLQLQRKQQIIRSGLSL
  22 PFGE..LHCVAA.L.PPP...PQ..F.--.....EPA.DS..S..LY.AMQIQRYQQAVRSTMVL
  23 PIKK..LHLVKK.M.GMVq..LE..V.NE.....PDD.DI..DleFY.QLQLQRQQQIIKSGLSL
  24 PIKK..LHLVKK.M.GMVq..LE..V.NE.....PDD.DI..DleFY.QLQLQRQQQIIKSGLSL
  25 PIKK..LHLVKK.M.GMVq..LE..V.SE.....PDD.DI..DleFY.QLQLQRQQQIIKSGLSL
  26 PIKK..LHLVQK.M.GMVq..LE..V.DD.....PDD.DIelS..FY.QLQLQRKQQIIRSGLSL
  27 PFGE..LHCVMA.L.PPP...PH..F.--.....DTS.DA..A..LY.AMQIQRYQQAVRSTMIL
  28 PFGE..LHCVMA.L.PPP...PH..F.--.....DTS.DA..A..LY.AMQIQRYQQAVRSTMVL
  29 PFGE..LHCVAA.L.PPT...PQ..F.--.....DDS.DA..E..LL.AMQKLRYQQMVRSTMVL
  30 PIKK..MHAVQN.M.GVVq..LE..I.AS.....PGD.DV..DliFY.QMQLARQEQIIKSALAL
  31 PIKK..MHAVQN.M.GVVq..LE..I.AS.....PSD.DV..DliFY.QMQLARQEQIIKSALAL
  32 FISN..VNSITR.N.AML...YD..A.LK.....AMK.FA..D..FA.VWSEARFSGMVKTALTL
  33 PIKA..LNLVKK.M.GMLh..LN..V.VE.....PDD.DI..DlsFY.HLQLQRQQQVIKSGLSL
  34 PIKA..LNLVKK.M.GMLh..LN..V.VE.....PDD.DI..DlsFY.HLQLQRQQQVIKSGLSL
  35 PFGE..LHCVAA.F.PPS...PQ..I.SR.....APE.DE..A..LT.KMQRQRYQQMVRSTMVL
  36 PIGE..LHCVAA.L.PAE...PT..LpLG.....ADA.DP..L..LV.SMQQQRYQQMVRSTLVL
  37 FIQQ..LSCQND.K.SLLn..FP..M.EK.....DENpDS..L..LY.QVKALRREKLIRSYLTL
  38 FMGN..LNAVTQ.N.KTL...FQ..L.IE.....KMK.FS..D..FT.IFNQTRYGNMVKTGLTL
  39 FIQG..LNVRQD.K.SFLn..LD..TkID.....GTK.DS..L..LY.QVKVLRREKLIRSYLIL
  40 FISN..VNSITR.N.AML...YD..A.LK.....AMK.FA..D..FS.VWSEARFSGMVKTA---
  41 FLQK..LTLLMD.K.SALd..FE..P.LI.....EDK.NS..L..TY.QMKSLRREKIIRSCLIL
  42 FLQK..LTLLMD.K.SALd..FE..P.LI.....EDK.NS..L..TY.QMKSLRREKIIRSCLIL
  43 RINA..ISAVAE.MiPIN...AD..D.NQ.....PEE.SS..H..FIvQMKLDHNRQVIKSSLIL
  44 RLNA..IRAVAKiL.PPN...LG..D.NQ.....LEE.SS..Hy.IV.QMKLEQNRQVIKSSLIL
  45 FIKNqaVLSSQQ.D.SFY...LE..S.IN.....QLK.FS..S..FE.SFSQMRYESLIKTVLKL
  46 FIKNqaVLSSQQ.D.CFY...LE..S.IN.....QLK.FS..S..FE.SFSQMRYESLIKTVLKL
  47 -LNR..INAIQK.M.MPIdyaPE..L.VE.....GMS.D-..D..MK.RMFLERHFQKVRSTIVL
  48 FISNqaVLSTQQ.D.SFY...LE..S.IN.....QLK.FS..S..FE.VFSQMRYESLIKTVLKL
  49 -LNK..VQAIQRiM.PIE...YDseM.VE.....TMS.GP..M..L-.QMFLGRHNQKVKSTIVL
  50 FAKD..LHHI-D.L.SPV...AD..L.LKfassvENK.DS..M..LY.QMQQIRLERVMRSSLIL


      60                  
      |                  
   1 AVTTTLKEL...T...P...
   2 AVTTILKEL...T...P...
   3 AVTTTLKEL...T...P...
   4 AVTTTLKEL...T...P...
   5 AVTTTLKEL...T...P...
   6 AVTTTLKEL...T...P...
   7 AVTTTLKEL...T...P...
   8 AVTTTLKEL...T...P...
   9 AVTTTLKEL...T...P...
  10 VVTTTLKEL...T...P...
  11 AVTTTLKEL...T...P...
  12 AVTTTLKEL...T...P...
  13 AVTTTLKEL...T...P...
  14 SITELLSRI...S...Lkqv
  15 SITELLSRI...S...Lkqv
  16 SITELLSRI...S...Qkqv
  17 SITELLSRI...S...Lkqv
  18 SLTELISRI...S...Lkka
  19 SLTELISKI...S...Lkka
  20 SITELLSRI...S...Vkqv
  21 AIVEICHEL...GkdsP...
  22 SLTELISKI...S...Lkka
  23 AIVEICNEL...GkdsP...
  24 AIVEICNEL...GkdsP...
  25 AIVEICNEL...GkdsP...
  26 AIVEICHEL...GkdsP...
  27 SLTELISKI...S...Lkka
  28 SLTELISKI...S...Lkka
  29 SLTELISRI...S...Lkka
  30 AIAGICNEL...GrdsP...
  31 AIAGICNEL...GrdsP...
  32 AVTTILKEL...T...P...
  33 AIIQICNAL...NkdsP...
  34 AIIQICNAL...NkdsP...
  35 SATEYLVRI...S...Akka
  36 SLTTLIAQI...S...Lkka
  37 AITEIYEQLqieS...P...
  38 AVTSLLQEL...T...Yesg
  39 SVTDLYDQLqveS...P...
  40 ---------...-...-...
  41 TIADIYRQLqieS...P...
  42 TIADIYRQLqieS...P...
  43 AITEIIKEL...H...Rdts
  44 AITEIIKEL...HrdtP...
  45 SCEMLIERI...E...Gein
  46 SCEMLIERI...E...Eein
  47 AVNDIHQQL...A...Kenv
  48 SCEMLLEKI...E...Eeit
  49 AITDIITTL...C...Rdna
  50 AITEINEKL...NvesP...