a2m2html output for tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0295
- gi|47226710|emb|CAG07869.1|_212:311 unnamed protein product [Tetraodon nigroviridis]
- gi|77748206|gb|AAI06333.1|_207:306 Unknown (protein for MGC:130862) [Xenopus laevis]
- gi|13874484|dbj|BAB46866.1|_214:313 hypothetical protein [Macaca fascicularis]
- gi|27151490|sp|Q95KJ0|DIMH_MACFA Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|67463767|pdb|1ZQ9|B_186:285 Chain B, Crystal Structure Of Human Dimethyladenosine Transferase [Taxonomy]
- gi|67463766|pdb|1ZQ9|A Chain A, Crystal Structure Of Human Dimethyladenosine Transferase [Taxonomy]
- gi|7657198|ref|NP_055288.1|_214:313 dimethyladenosine transferase [Homo sapiens]
- gi|14790071|gb|AAH10874.1| Dimethyladenosine transferase [Homo sapiens]
- gi|4050050|gb|AAC97955.1| putative dimethyladenosine transferase [Homo sapiens]
- gi|27151492|sp|Q9UNQ2|DIMH_HUMAN Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|76646158|ref|XP_586750.2|_214:313 PREDICTED: similar to Probable dimethyladenosine transferase (S-adenosylmethionine-6-N,N-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) (HUSSY-05) isoform 1 [Bos taurus]
- gi|86438246|gb|AAI12887.1| Dimethyladenosine transferase [Bos taurus]
- gi|3646270|emb|CAA08815.1|_58:157 putative dimethyladenosine transferase [Homo sapiens]
- gi|76646156|ref|XP_878963.1|_61:160 PREDICTED: similar to Probable dimethyladenosine transferase (S-adenosylmethionine-6-N,N-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) (HUSSY-05) isoform 2 [Bos taurus]
- gi|3859994|gb|AAC72947.1|_26:125 unknown [Homo sapiens]
- gi|62642979|ref|XP_215477.3|_319:418 PREDICTED: similar to RIKEN cDNA 1500031M22 [Rattus norvegicus]
- gi|74222329|dbj|BAE26964.1|_214:313 unnamed protein product [Mus musculus]
- gi|18043925|gb|AAH19799.1|_214:313 RIKEN cDNA 1500031M22 [Mus musculus]
- gi|21313560|ref|NP_079723.1| dimethyladenosine transferase [Mus musculus]
- gi|74148362|dbj|BAE36330.1| unnamed protein product [Mus musculus]
- gi|12847736|dbj|BAB27687.1| unnamed protein product [Mus musculus]
- gi|27151491|sp|Q9D0D4|DIMH_MOUSE Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|26347035|dbj|BAC37166.1|_61:160 unnamed protein product [Mus musculus]
- gi|72008162|ref|XP_779962.1|_201:300 PREDICTED: similar to dimethyladenosine transferase [Strongylocentrotus purpuratus]
- gi|66523698|ref|XP_624425.1|_207:306 PREDICTED: similar to ENSANGP00000016944 [Apis mellifera]
- gi|91091694|ref|XP_972612.1|_207:306 PREDICTED: similar to CG11837-PA [Tribolium castaneum]
- gi|57525891|ref|NP_001003556.1|_207:306 hypothetical protein LOC445162 [Danio rerio]
- gi|50417873|gb|AAH78286.1| Zgc:101122 [Danio rerio]
- gi|21358017|ref|NP_651660.1|_207:306 CG11837-PA [Drosophila melanogaster]
- gi|16769516|gb|AAL28977.1| LD35950p [Drosophila melanogaster]
- gi|27151493|sp|Q9VAQ5|DIMH_DROME Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|7301735|gb|AAF56847.1| CG11837-PA [Drosophila melanogaster]
- gi|54638406|gb|EAL27808.1|_207:306 GA11224-PA [Drosophila pseudoobscura]
- gi|6048291|emb|CAB58154.1|_208:307 dim1 [Schizosaccharomyces pombe]
- gi|19112914|ref|NP_596122.1| hypothetical protein SPBC336.02 [Schizosaccharomyces pombe 972h-]
- gi|26556992|sp|Q9USU2|DIM1_SCHPO Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|55624270|ref|XP_517743.1|_214:316 PREDICTED: putative dimethyladenosine transferase [Pan troglodytes]
- gi|55240843|gb|EAA09266.2|_207:306 ENSANGP00000016944 [Anopheles gambiae str. PEST]
- gi|58385178|ref|XP_313763.2| ENSANGP00000016944 [Anopheles gambiae str. PEST]
- gi|50293399|ref|XP_449111.1|_214:317 unnamed protein product [Candida glabrata]
- gi|49528424|emb|CAG62081.1| unnamed protein product [Candida glabrata CBS138]
- gi|52782776|sp|Q6FKY3|DIM1_CANGA Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|6324989|ref|NP_015057.1|_214:318 Essential 18S rRNA dimethylase, responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18 S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing; Dim1p [Saccharomyces cerevisiae]
- gi|1370549|emb|CAA98001.1| DIM1 [Saccharomyces cerevisiae]
- gi|1169344|sp|P41819|DIM1_YEAST Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|601876|gb|AAA57357.1| dimethyladenosine transferase [Taxonomy]
- gi|44981468|gb|AAS51253.1|_214:319 ACR026Wp [Ashbya gossypii ATCC 10895]
- gi|45185713|ref|NP_983429.1| ACR026Wp [Eremothecium gossypii]
- gi|52782780|sp|Q75C90|DIM1_ASHGO Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|57229319|gb|AAW45752.1|_226:325 rRNA (adenine-N6,N6-)-dimethyltransferase, putative [Cryptococcus neoformans var. neoformans JEC21]
- gi|58259713|ref|XP_567269.1| rRNA (adenine-N6,N6-)-dimethyltransferase [Cryptococcus neoformans var. neoformans JEC21]
- gi|50255682|gb|EAL18415.1| hypothetical protein CNBJ3380 [Cryptococcus neoformans var. neoformans B-3501A]
- gi|49654352|emb|CAG86824.1|_216:327 unnamed protein product [Debaryomyces hansenii CBS767]
- gi|50420303|ref|XP_458685.1| hypothetical protein DEHA0D05819g [Debaryomyces hansenii CBS767]
- gi|52782772|sp|Q6BSY5|DIM1_DEBHA Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|68467333|ref|XP_722328.1|_216:326 putative dimethyladenosine transferase [Candida albicans SC5314]
- gi|68467562|ref|XP_722214.1| putative dimethyladenosine transferase [Candida albicans SC5314]
- gi|46444295|gb|EAL03571.1| likely dimethyladenosine transferase [Candida albicans SC5314]
- gi|46444170|gb|EAL03447.1| likely dimethyladenosine transferase [Candida albicans SC5314]
- gi|39589178|emb|CAE57911.1|_208:307 Hypothetical protein CBG00961 [Caenorhabditis briggsae]
- gi|50551823|ref|XP_503386.1|_214:317 hypothetical protein [Yarrowia lipolytica]
- gi|49649255|emb|CAG78965.1| unnamed protein product [Yarrowia lipolytica CLIB122]
- gi|52782774|sp|Q6C7H6|DIM1_YARLI Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|50306253|ref|XP_453098.1|_215:320 DIM1_KLULA [Kluyveromyces lactis]
- gi|49642232|emb|CAH00194.1| DIM1_KLULA [Kluyveromyces lactis NRRL Y-1140]
- gi|52788270|sp|P78697|DIM1_KLULA Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|71013449|ref|XP_758591.1|_235:334 hypothetical protein UM02444.1 [Ustilago maydis 521]
- gi|46098249|gb|EAK83482.1| hypothetical protein UM02444.1 [Ustilago maydis 521]
- gi|90306003|gb|EAS35634.1|_185:346 hypothetical protein CIMG_00988 [Coccidioides immitis RS]
- gi|23497221|gb|AAN36768.1|_252:353 dimethyladenosine transferase, putative [Plasmodium falciparum 3D7]
- gi|23509377|ref|NP_702044.1| dimethyladenosine transferase, putative [Plasmodium falciparum 3D7]
- gi|20803714|emb|CAA87382.2|_208:307 Hypothetical protein E02H1.1 [Caenorhabditis elegans]
- gi|25146882|ref|NP_496061.2| E02H1.1 [Caenorhabditis elegans]
- gi|27808654|sp|Q09522|DIMI_CAEEL Probable dimethyladenosine transferase (S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [Taxonomy]
- gi|37531758|ref|NP_920181.1|_88:233 putative dimethyladenosine transferse [Oryza sativa (japonica cultivar-group)]
- gi|21321758|gb|AAM47293.1| Putative dimethyladenosine transferse [Oryza sativa (japonica cultivar-group)]
- gi|18657022|gb|AAL78109.1| Putative dimethyladenosine transferse [Oryza sativa]
- gi|31430574|gb|AAP52468.1| hypothetical protein LOC_Os10g10440 [Oryza sativa (japonica cultivar-group)]
- gi|1806115|emb|CAA92586.1|_215:320 dimethylase [Kluyveromyces lactis]
- gi|68071473|ref|XP_677650.1|_253:354 dimethyladenosine transferase [Plasmodium berghei strain ANKA]
- gi|56497848|emb|CAH94950.1| dimethyladenosine transferase, putative [Plasmodium berghei]
- gi|82753583|ref|XP_727737.1|_226:327 dimethyladenosine transferase [Plasmodium yoelii yoelii str. 17XNL]
- gi|23483724|gb|EAA19302.1| dimethyladenosine transferase, putative [Plasmodium yoelii yoelii]
- gi|70953687|ref|XP_745929.1|_253:354 Plasmodium chabaudi chabaudi dimethyladenosine transferase [Plasmodium chabaudi chabaudi]
- gi|56526401|emb|CAH78914.1| dimethyladenosine transferase, putative [Plasmodium chabaudi]
- gi|66810281|ref|XP_638864.1|_213:314 hypothetical protein DDB0185676 [Dictyostelium discoideum]
- gi|60467487|gb|EAL65509.1| hypothetical protein DDBDRAFT_0185676 [Dictyostelium discoideum AX4]
- gi|4572637|emb|CAA92585.1|_208:306 dimethylase [Schizosaccharomyces pombe]
- gi|11256767|pir||T43249 rRNA (adenine-N6,N6-)-dimethyltransferase (EC 2.1.1.-) - fission yeast (Schizosaccharomyces pombe) [Taxonomy]
- gi|39975205|ref|XP_368993.1|_228:390 hypothetical protein MG00251.4 [Magnaporthe grisea 70-15]
- gi|89308905|gb|EAS06893.1|_175:345 dimethyladenosine transferase family protein [Tetrahymena thermophila SB210]
- gi|65304135|emb|CAI76514.1|_250:351 dimethyladenosine transferase, putative [Theileria annulata]
- gi|84996835|ref|XP_953139.1| dimethyladenosine transferase [Theileria annulata strain Ankara]
- gi|50057288|emb|CAH03272.1|_196:353 Ribosomal RNA adenine dimethylase, putative [Paramecium tetraurelia]
- gi|50404911|ref|YP_054003.1| Ribosomal RNA adenine dimethylase, putative [Paramecium tetraurelia]
- gi|71028934|ref|XP_764110.1|_261:362 dimethyladenosine transferase [Theileria parva strain Muguga]
- gi|68351064|gb|EAN31827.1| dimethyladenosine transferase, putative [Theileria parva]
- gi|15226591|ref|NP_182264.1|_212:353 S-adenosylmethionine-dependent methyltransferase/ rRNA (adenine-N6,N6-)-dimethyltransferase/ rRNA methyltransferase [Arabidopsis thaliana]
- gi|21280901|gb|AAM44912.1| putative dimethyladenosine transferase [Arabidopsis thaliana]
- gi|14532650|gb|AAK64053.1| putative dimethyladenosine transferase [Arabidopsis thaliana]
- gi|2529685|gb|AAC62868.1| putative dimethyladenosine transferase [Arabidopsis thaliana]
- gi|67525711|ref|XP_660917.1|_223:403 hypothetical protein AN3313.2 [Aspergillus nidulans FGSC A4]
- gi|40744101|gb|EAA63281.1| hypothetical protein AN3313.2 [Aspergillus nidulans FGSC A4]
- gi|85099447|ref|XP_960790.1|_224:398 hypothetical protein [Neurospora crassa OR74A]
- gi|32421833|ref|XP_331360.1| hypothetical protein [Neurospora crassa]
- gi|28922314|gb|EAA31554.1| hypothetical protein [Neurospora crassa]
- gi|7498306|pir||T20417_208:303 hypothetical protein E02H1.1 - Caenorhabditis elegans [Taxonomy]
- gi|70987085|ref|XP_749024.1|_218:392 dimethyladenosine transferase [Aspergillus fumigatus Af293]
- gi|66846654|gb|EAL86986.1| dimethyladenosine transferase [Aspergillus fumigatus Af293]
- gi|71656161|ref|XP_816632.1|_245:344 ribosomal RNA adenine dimethylase family protein [Trypanosoma cruzi]
- gi|70881773|gb|EAN94781.1| ribosomal RNA adenine dimethylase family protein, putative [Trypanosoma cruzi]
- gi|71425341|ref|XP_813086.1|_245:344 ribosomal RNA adenine dimethylase family protein [Trypanosoma cruzi]
- gi|70877938|gb|EAN91235.1| ribosomal RNA adenine dimethylase family protein, putative [Trypanosoma cruzi]
- gi|83765282|dbj|BAE55425.1|_219:392 unnamed protein product [Aspergillus oryzae]
- gi|62359277|gb|AAX79719.1|_245:344 ribosomal RNA adenine dimethylase family protein, conserved [Trypanosoma brucei]
- gi|70801818|gb|AAZ11724.1| ribosomal RNA adenine dimethylase family protein, conserved [Trypanosoma brucei]
- gi|71752811|ref|XP_825820.1| ribosomal RNA adenine dimethylase family protein, conserved [Trypanosoma brucei TREU927]
- gi|32398681|emb|CAD98641.1|_238:340 dimethyladenosine transferase, probable [Cryptosporidium parvum]
- gi|66475300|ref|XP_627466.1| Dim1p-like ERMB/KSGA methylase [Cryptosporidium parvum Iowa II]
- gi|46228931|gb|EAK89780.1| Dim1p-like ERMB/KSGA methylase [Cryptosporidium parvum]
- gi|67464821|ref|XP_648602.1|_196:295 dimethyladenosine transferase [Entamoeba histolytica HM-1:IMSS]
- gi|56464806|gb|EAL43214.1| dimethyladenosine transferase, putative [Entamoeba histolytica HM-1:IMSS]
- gi|68127680|emb|CAJ05804.1|_254:374 ribosomal RNA adenine dimethylase family protein, putative [Leishmania major]
- gi|46121341|ref|XP_385225.1|_213:346 hypothetical protein FG05049.1 [Gibberella zeae PH-1]
- gi|42551545|gb|EAA74388.1| hypothetical protein FG05049.1 [Gibberella zeae PH-1]
- gi|42573814|ref|NP_975003.1|_244:369 S-adenosylmethionine-dependent methyltransferase/ rRNA (adenine-N6,N6-)-dimethyltransferase/ rRNA methyltransferase [Arabidopsis thaliana]
- gi|30698221|ref|NP_201437.2|_216:341 S-adenosylmethionine-dependent methyltransferase/ rRNA (adenine-N6,N6-)-dimethyltransferase/ rRNA methyltransferase [Arabidopsis thaliana]
- gi|31711838|gb|AAP68275.1| At5g66360 [Arabidopsis thaliana]
- gi|21539437|gb|AAM53271.1| dimethyladenosine transferase-like protein [Arabidopsis thaliana]
- gi|71078547|ref|XP_778360.1|_194:315 dimethylase [Giardia lamblia ATCC 50803]
- gi|29246610|gb|EAA38200.1| GLP_13_6796_7746 [Giardia lamblia ATCC 50803]
- gi|47157009|gb|AAT12376.1|_133:219 putative dimethyladenosine transferase-like protein [Antonospora locustae]
- gi|19074123|ref|NP_584729.1|_189:277 DIMETHYLADENOSINE TRANSFERASE [Encephalitozoon cuniculi GB-M1]
- gi|19068765|emb|CAD25233.1| DIMETHYLADENOSINE TRANSFERASE [Encephalitozoon cuniculi GB-M1]
- gi|12803983|gb|AAH02841.1|_214:274 HSA9761 protein [Homo sapiens]
- gi|50937619|ref|XP_478337.1|_122:261 Ribosomal RNA adenine dimethylase-like protein [Oryza sativa (japonica cultivar-group)]
- gi|34394642|dbj|BAC83949.1| Ribosomal RNA adenine dimethylase-like protein [Oryza sativa (japonica cultivar-group)]
- gi|50761519|ref|XP_424746.1|_364:416 PREDICTED: similar to HSA9761 protein [Gallus gallus]
- gi|76163024|gb|AAX30781.2|_1:92 SJCHGC07661 protein [Schistosoma japonicum]

                          10        20          30                40   
                          |         |           |                 |   
   1 .....S...S.F...LTNFDEWDNLLRICFSRKRKTLHA.IF.KRN.AVLNM..LE.....HNYK
   2 pknp.P...P.P...I-NFQEWDGLVRIAFVRKNKTLSA.AF.KSS.AVEQL..LE.....KNYR
   3 pknp.P...P.P...I-NFQEWDGLVRIAFVRKNKTLAA.SF.KST.AVQEL..LE.....KNYR
   4 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
   5 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
   6 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
   7 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
   8 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
   9 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  10 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  11 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  12 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  13 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  14 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  15 prnp.P...P.P...I-NFQEWDGLVRIAFVRKNKTLSA.AF.RNK.GVVEM..LE.....KNYR
  16 prnp.P...P.P...I-NYQEWDGLTRIAFVRKNKTLSA.AF.KQT.TVLTM..LE.....KNYK
  17 prnp.P...P.P...I-SYTEWDGLTRIAFSRKNKTLGA.AF.RQS.VVLAT..LE.....KNYK
  18 pknp.P...P.P...V-NFQEWDGLVRIAFVRKNKMLSA.AF.KSA.AVEKL..LE.....KNYK
  19 pknp.P...P.P...V-NFTEWDGLTRIAFLRKNKTLAA.TF.KVT.SVLEM..LE.....KNYK
  20 pknp.P...P.P...V-NFTEWDGLTRIAFLRKNKTLAA.TF.KVS.SVIEM..LE.....KNYK
  21 pknp.P...P.P...L-AFEEWDGLLRIVFLRKNKTIGA.CF.KTS.SIIEM..VE.....NNYR
  22 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  23 prnp.P...P.P...I-NYTEWDGLTRIAFLRKNKTLAA.AF.KQT.TVLTT..LE.....DNFK
  24 iknp.R...P.Q...I-DFNEWDGLLRIVFVRKNRTISA.GF.KST.TVLEI..LE.....KNYK
  25 iknp.R...P.Q...V-DYNEWDGLLRIVFVRKNRTISA.GF.KST.TVMDI..LE.....KNYK
  26 iktp.R...P.P...V-DFNEWDGLLRIVFVRKNRTISA.GF.KST.AVLEI..ME.....KNYK
  27 prdp.P...P.P...V-KFEEFDGLNRIIFSRANKTLRA.GF.KAK.GVVEL..LE.....KNYR
  28 vkvp.R...P.N...I-DFNEWDGLLRICFVRKNKTIAA.GF.KSN.NILDI..LE.....KNYK
  29 iknp.R...P.N...I-DFNEWDGLLRIVFVRKNKTIAA.GF.KSS.NVIEI..LE.....KNYK
  30 pknp.P...P.P...V-NFVEWEGLLRLCFMRKNKTLLA.IF.RLS.NVIEV..IE.....DNYR
  31 vknp.R...P.P...I-DFNEWDGLLRVCFVRKNKTINA.GF.KTS.AVLAV..LE.....KNYQ
  32 iknp.R...P.Q...V-DFNEWDGLLRIVFVRKNRTIAA.GF.KST.TVLEI..LE.....KNYK
  33 plnp.P...P.A...I-PFEEFDGLTRIVFSRRNKTVRAsFF.DAR.GVIDM..LE.....SNYK
  34 pktp.R...P.D...I-SYDEWDGLLRIAFVRKNKTLRS.SFlGTS.SVLSM..LE.....SNYT
  35 klip.K...E.SsflT-NFDEWDNLLRICFSRKRKTLHA.IF.KRN.AVLNM..LE.....HNYK
  36 pknp.P...P.P...V-NFVEWEGLLRLCFMRKNKTLMA.IF.RLS.NVIEV..IE.....DNFR
  37 p....RkplP.P...V-SFKEWDGLVRLCFNRKNKTLGA.IF.KQK.RVLEL..LE.....KNYK
  38 iknp.R...P.Q...V-DFNEWDGLLRIVFVRKNRTIAA.GF.KST.TDLEI..LE.....KNYK
  39 klip.K...E.NnsmI-NFDEWDNLLRICFSRKRKTLHA.IF.KRN.AVLNM..LE.....HNYK
  40 klip.K...E.NnsmI-NFDEWDNLLRICFSRKRKTLHA.IF.KRN.AVLNM..LE.....HNYK
  41 klip.K...E.NnsmI-NFDEWDNLLRICFSRKRKTLHA.IF.KRN.AVLNM..LE.....HNYK
  42 pfnp.P...P.P...I-NFVEWDGLVKLCFSRKNKTLSG.IF.RVS.SVIET..LN.....QNYK
  43 pknp.P...P.P...L-AFEEWDGLLRIVFLRKNKTIGA.CF.KTS.SIIEM..VE.....NNYR
  44 lgre.R...P.N...V-SWEEWDGMLRVCFNRKNKTLHA.SFlGVK.EVLAM..AE.....RNYK
  45 pknp.A...P.V...L-NYIEWDGLLRVCFMRKNKQLSA.IF.KNK.SVLQV..LE.....KNFE
  46 kivp.Rqq.PlV...V-DFGEWDGMIRICFSRKRRTLRS.LF.KKQ.SVLSI..LE.....SNYK
  47 pknp.I...P.N...I-NYIEWDGLLRICFNRKNKQLSA.IF.KNK.SVLKT..LE.....HNFH
  48 kivp.Req.PlV...V-DFGEWDGMIRICFSRKRRTLRS.LF.KKQ.SVLSI..LE.....SNYK
  49 p....RrpgP.Q...V-NKKEWDGFLRVCFIRKNKTLGS.IF.KQK.SVLSM..LE.....KNFK
  50 riep.KlgkP.E...I-SWDEWDGMLRICFVRKNKTLRA.GF.MAT.KIRQM..IE.....RNWI
  51 vgsa.R...P.N...I-AFEEFDGLLRIAFNRKNKTLYA.GF.NQK.EVLNM..CE.....RNYK
  52 pkn..P...P.P...----PEWEGLLRLCFMRKNKTLMA.IF.RLS.NVIEV..IE.....DNFR
  53 ri7adR...P.N...I-SWDEWDGMLRICFVRKNKTLRA.GF.MAT.KVRAL..IE.....RNWI
  54 pkhp.A...P.D...V-DFEEWDGLVKFIFNRKNKKVSS.IF.RTK.NAVQT..LY.....EKYC
  55 pkhp.A...P.D...V-DFEEWDGLVKFIFNRKNKKVSS.IF.RTK.NAVQT..LY.....EKYC
  56 rv7sdR...P.A...I-SWDEWDGMLRICFVRKNKTLRA.GF.MGN.KTRAM..IE.....RNWI
  57 pkhp.A...P.S...V-DFEEWDGLVKHIFNRKNKKVSS.IF.RTK.NTVRT..LY.....DKYC
  58 kfep.Kki.PvS...V-NFREWDGLMRICFSRKKKTIRA.NF.NNS.SVLNI..LE.....NNYK
  59 pvkp.A...P.P...L-NLVEFDGFLRICFLRKHKTLSS.LF.RIS.SVLEV..ME.....KNLR
  60 pkyp.P...P.D...V-DFEEWDGLVKMLFSRKNKKSSS.IF.RTK.AAAQA..LY.....DKYV
  61 riep.RtdvP.A...V-GLEELDGVLRICFSRKNKTLRA.SF.LDS.H--EI..CE.....RNWI
  62 ritp.KeiiP.D...V-NVQEWLAFTRTCFGKKNKTLGS.MF.RQKkKVMELqsLSagrhgSNVE
  63 kitp.KeiiP.D...V-NVQEWLAFTRTCFGKKNKTLGS.MF.RQKkKVMELqsLSagrhgSNVE
  64 pvgp.P...P.G...L-DLDEFNGLTRILFSKKNKTLGA.IF.KTK.SLLDD..LA.....NNIA
  65 prvp.R...P.P...I-NIEEFNRLLKICFLRKNKRLSG.IF.KRT.VIQDM..--.....----
  66 prip.R...P.P...I-DLGEFDRFLKICFLRKNKTLRA.NF.KNS.SLVSK..IK.....ND--
  67 pknp.P...P.P...I-NFQEWDGLVRITFVRKNKTLSA.AF.KSS.AVQQL..LE.....KNYR
  68 eirp.RaaeP.N...V-DLAEWLAFTRSCFGQKNKTLGA.IF.KQKrKVLEL..FR.....RSRC
  69 pknp.P...P.P...I-NFQEWDGLVRIAFVRKNKTLSA.AF.KSS.AVEQL..LD.....HNYR
  70 .....-...-.-...-----EWDGLLRLVFARKNKTIGA.NL.GGK.SIASH..LR.....KIYM


              50                    60         70        80        90  
              |                     |          |         |         |  
   1 NWC.TL..NK.QV.PV.N..F..P.....FKKYCLDVLE.HLDMCEKRSINLDENDFLKLLLEFN
   2 IHC.SLh.NV.TI.PA.D..F..S.....IAKKIEGVLQ.EASFCEKRARSMDIDDFMVLLHAFN
   3 IHC.SLh.NI.SV.PE.N..F..S.....IAEKIEGILT.ETGFSEKRARSMDIDDFMALLHGFN
   4 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
   5 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
   6 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
   7 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
   8 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
   9 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
  10 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
  11 IHC.SVq.NT.VI.PE.D..F..S.....IADKIQQILT.NTGFSDKRARSMDIDDFIRLLHGFN
  12 IHC.SVq.NT.VI.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
  13 IHC.SVq.NT.VI.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
  14 IHC.SVq.NT.VI.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
  15 VHC.SVk.NI.AI.PD.N..L..D.....MKEKVVSVLE.KIEFEGKRARTMDIDDFLKLLSSFN
  16 LHC.SLn.NK.II.TE.G..F..N.....IKDMISDILQ.KADAENKRARTMDIDDFISLLHAFN
  17 SFC.SVn.NK.EI.PP.G..F..N.....IKEKVEQVLK.QVEGDQKRARTMDIDDFMVLLHAFN
  18 IHC.SVh.NI.EI.PE.D..F..N.....IAPKIESILQ.ESKFSDKRARSMDIDDFMVLLHAFN
  19 LYR.SLr.NE.PI.ED.D..F..K.....MQDKVISILE.EQDMAAKRARSMDIDDFMRLLLAFN
  20 VFR.SLr.NE.PL.EE.G..F..N.....MQEKVIGILE.ELEMATLRARSMDIDDFMRLLRAFN
  21 TWC.SQ..NErMV.EE.D..F..D.....VKSLIDGVLQ.QCNLQDARASKCGQTEFLSLLHAFH
  22 IHC.SVh.NI.II.PE.D..F..S.....IADKIQQILT.STGFSDKRARSMDIDDFIRLLHGFN
  23 LHC.SLk.NI.DV.PA.D..L..N.....VKEMVEKILE.KADASDKRARSMDIDDFMAVLQAFN
  24 TFL.AI..NN.QS.ID.E..T..EnlqslIKQKIETVLK.ETGLAEKRAGKCDQTDFLKLLYAFH
  25 TFL.AM..NN.EM.VD.D..T..Kgs6dvVKEKIDTVLK.ETDLGDKRAGKCDQNDFLRLLYAFH
  26 AYL.ATt.ND.AM.VD.D..A..Kgs6eqVKQKIETVLA.ETGLSDKRAGKCDQTDFLKLLYAFH
  27 TWCaEQ..GA.II.ED.N..F..D.....IREKVESILV.ETGFADSRAAKMDVDDLLKLLAAFN
  28 TFL.STa.NA.AA.NG.D..D..Sm12diVKAKIEQVLT.ETGFSDKRAAKLDQTDFLKLLYAFH
  29 TFL.AT..QE.SN.NN.D..S..Mm12dvVKNKITTVLT.ETGFSDKRAGKLDQTDFLKLLYAFH
  30 KVC.SMk.NK.PL.PK.D..F..N.....MKKLIEETLT.ASGYAENRARKMRVEDFLALLLAFN
  31 TWL.STq.GE.II.PE.G..S..Nlsdv.VKQKINKILT.DTGIGEMRSAKCDQTEFLTLLNEFH
  32 AFL.AT..QS.AV.PT.T..S..Sgd7neVKEKIEQVLS.ETGLAEKRAGKCDQTDFLKLLYGFH
  33 TYC.AV..KE.IM.PE.Q..G..S.....FADMVKQVLV.ETGSAENRAAKMDIDDLLTLLAAFH
  34 TWC.AQ..ND.-I.PV.E..V..Gp62klVRKKVRQVLEdDTGLADKRARMCDEGDFLKLLWSFN
  35 NWC.TL..NK.QV.PV.N..F..P.....FKKYCLDVLE.HLDMCEKRSINLDENDFLKLLLEFN
  36 KVC.SFk.NK.PI.PK.D..L..N.....MKKVIEETLT.ASGYGESRARKMRVEDFLALLLAFN
  37 TMQ.SL..QL.TS.DA.E..K..Ge47acFKEKIMGILQ.QGDFAEKRASKLSQVDFLYLLSLFN
  38 AFL.AT..QS.AV.PT.T..S..Sgd7neVKEKIEQVLS.ETGLAEKRAGKCDQTDFLKLLYGFH
  39 NYC.TF..NK.II.PI.N..Y..S.....FKTFCLDTLK.DLEMEEQRSINLDENDFLKLLLEFN
  40 NYC.TF..NK.IV.PI.N..Y..S.....FKTFCLDTLK.DLEMEEQRSINLDENDFLKLLLEFN
  41 NYC.TF..NK.IV.PI.N..Y..S.....FKTFCLDTLK.DLEMEEQRSINLDENDFLKLLLEFN
  42 TYC.AL..EG.KM.NT.D..G..Sdeq..MKELIIKTLT.DNDFLDSRSSKLDINDFLKLLNKFH
  43 TWC.SQ..NErMV.EE.D..F..D.....VKSLIDGVLQ.QCNLQDARASKCGQQS-LSLLHPFH
  44 VWC.TM..ND.-I.PI.D..E..Sv64elVRSKIEKVLK.DTDLAEQRANKCDQNDFLRLLAAFN
  45 TYQ.KI..KA.IE.QG.A..V..Ee72klFKEKIHKILE.DSGYLEKRPAKLDIDDYLKLLFVFN
  46 SWC.TI..NN.KV.PV.Y..K..P.....FKEFVIEILE.SSGLAERRSITVSIAEFLKLLLAFN
  47 VIE.QE..GI.KV.ND.P..A..Nn59npFRLKINEILK.TNDMFQKRPVKMDNDDFLQLLCAMN
  48 SWC.TI..NN.KV.PV.V..K..P.....FKEFVIEILE.GSGLAERRSITVSIAEFLKLLLAFN
  49 TLQ.AV..LA.SL.QN.N..G..Ep43seFKEKVMNVLK.EGGFEEKRSSKLSQQEFLYLLSLFN
  50 TWA.AMhpEK.VS.QG.D..V..Dl77rlIQFKIERILD.TAGLANHRANKCDENDFLRLLHACN
  51 VYC.TL..NN.-I.PI.D..E..Sl77liVKAKLNKVLT.STGLADKRARQCDQNDFLKLLLAFH
  52 KVC.SFk.NK.PI.PK.D..L..N.....MKKVIEETLT.ASGYGESRARKMRVEDFLALLLAFN
  53 TWV.SMhpEK.VT.QA.D..I..Df71klVQAKIQRVLE.QTNLANARAQKCDENNFLRLLHGFN
  54 SYQ.KM..EG.KT.SV.KslA..E.....FKEHLETVMQ.D-PVFESRARLLDQDSITKLLCHFT
  55 SYQ.KM..EG.KT.SV.KslA..E.....FKEHLETVMQ.D-PVFESRARLLDQDSITKLLCHFT
  56 TFA.TMypEK.VT.QA.D..I..Df70klIQVKLQRILD.RTELANARAQKCDENDFLRLLHACN
  57 SYQ.RM..EG.VK.DV.K..TfeE.....FRQHLESILQ.E-PIFDKRARVLDQESIMELLCCFT
  58 VWS.SI..NQ.KD.PCgN..M..P.....FKTFIFKILE.DSGLSSKRGFNVDINEYFRLLFEFN
  59 IIA.KIr.NI.PI.DE.N..L..D.....VKADVLQILE.ESGRAKSRAAQLTLDDFLELIYAFM
  60 SYR.KM..EG.GQ.PV.G..T..At23eqFRVLLAAVIA.D-PMFEQRSRMLDEVALMTMLAHFI
  61 TWT.SMypDK.VS.EK.D..L..Dl32nlIRTKIEHVLE.TTELAEARAVKCDENDFLKLILAFR
  62 VMN.QT..GG.DS.DS.D..V..Ee16smFKERVIEILR.TNGFEEKRPSKLSHRELLHLLSLFN
  63 VMN.QT..GG.DS.DS.D..V..Ee16smFKERVIEILR.TNGFEEKRPSKLSHRELLHLLSLFN
  64 RLD.EI..SR.LHkPA.Q..H..Eg22vqLRERIAEALA.EANLTDTRPNHMAIPDLLSLMCALA
  65 --Q.KV..NK.AY.TL.Q..-..E.....IEKKTTGILR.KLGA--DRAAKMDIEDFLFLLLEFK
  66 --P.NF..EN.TT.PD.D..V..-.....----FERVLS.GADLAGARAAKMDLDDFLALLLEFR
  67 IHC.SV..HN.IV.SA.A..Vy.P.....VKQI------.-------------------------
  68 AEE.RC..DG.NA.NA.G..G..Gs37avFKAKITGALE.SCELAGKRPSKLSNDELLRLLKLLN
  69 IHC.SL..HN.AV.SS.F..L..-.....----------.-------------------------
  70 ETC.CT..KG.LS.PT.P..E..Vi10vaMEEKISSILR.DSGFEKKRARTLDEDDFLRLLLAQT


                   
                  
   1 KK...GIHFF...
   2 SA...GIHFS...
   3 SQ...GIHFT...
   4 AE...GIHFS...
   5 AE...GIHFS...
   6 AE...GIHFS...
   7 AE...GIHFS...
   8 AE...GIHFS...
   9 AE...GIHFS...
  10 AE...GIHFS...
  11 AE...GIHFS...
  12 AE...GIHFS...
  13 AE...GIHFS...
  14 AE...GIHFS...
  15 TE...GIHFS...
  16 AK...GVHFI...
  17 SE...GIHFS...
  18 SA...GIHFS...
  19 SA...GIHFN...
  20 SK...GIHFN...
  21 QV...GVHFA...
  22 AEvsvTIAYLfry
  23 AE...GFHFS...
  24 QV...GIHFS...
  25 QV...GIHFS...
  26 QV...GLHFS...
  27 VE...GIHFA...
  28 QV...GLHFA...
  29 QV...GIHFA...
  30 KA...DIHFLs..
  31 KA...GIYFA...
  32 QV...GIHFA...
  33 EK...GIHFS...
  34 QR...GIHFN...
  35 KK...GIHFFnis
  36 KA...DIHFLs..
  37 KA...GIHFS...
  38 QV...GIHFA...
  39 KK...GIRFFnia
  40 KK...GIRFFnia
  41 KK...GIRFFnia
  42 ET...GIHFK...
  43 QV...GRSFWlmg
  44 AE...GIHFA...
  45 QN...EIHFK...
  46 EV...GIHFCnia
  47 AQ...GIHFK...
  48 EV...GIHFCnia
  49 KS...GIHFT...
  50 TE...GIHFS...
  51 EE...GIHFS...
  52 KA...DIHFLs..
  53 TE...GIHFS...
  54 EN...GIHFV...
  55 EN...GIHFV...
  56 KE...GIHFS...
  57 KN...DIHFV...
  58 KN...GVHFVnii
  59 KK...NYHFC...
  60 KH...GIHFI...
  61 EN...NIYFT...
  62 QA...GIFFHdit
  63 QA...GIFFHdit
  64 AK...GVRFTn..
  65 KE...GISF-...
  66 KV...NIYF-...
  67 --...-----...
  68 EQ...GVRFQ...
  69 --...-----...
  70 I-...-----...