a2m2html output for tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0361 A putative transcriptional regulator, Shigella flexneri 2a str. 2457T, 169 res
- gi|82545446|ref|YP_409393.1|_2:169 putative transcriptional regulator [Shigella boydii Sb227]
- gi|81246857|gb|ABB67565.1| putative transcriptional regulator [Shigella boydii Sb227]
- gi|16130830|ref|NP_417404.1|_2:168 predicted DNA-binding transcriptional regulator [Escherichia coli K12]
- gi|1789297|gb|AAC75966.1| predicted DNA-binding transcriptional regulator [Escherichia coli K12]
- gi|89109707|ref|AP_003487.1| predicted DNA-binding transcriptional regulator [Escherichia coli W3110]
- gi|1723852|sp|P11663|YGGD_ECOLI Hypothetical protein yggD [Taxonomy]
- gi|85675740|dbj|BAE76993.1| predicted DNA-binding transcriptional regulator [Escherichia coli W3110]
- gi|882458|gb|AAA69096.1| ORF_f169; alternate name yggD; orf2 of X14436 [Taxonomy]
- gi|83587671|ref|ZP_00926298.1|_2:168 COG3722: Transcriptional regulator [Escherichia coli 101-1]
- gi|75239498|ref|ZP_00723469.1|_2:168 COG3722: Transcriptional regulator [Escherichia coli E110019]
- gi|75187649|ref|ZP_00700916.1| COG3722: Transcriptional regulator [Escherichia coli E24377A]
- gi|24053327|gb|AAN44400.1|_2:168 putative transcriptional regulator [Shigella flexneri 2a str. 301]
- gi|24114183|ref|NP_708693.1| putative transcriptional regulator [Shigella flexneri 2a str. 301]
- gi|30042499|gb|AAP18223.1| putative transcriptional regulator [Shigella flexneri 2a str. 2457T]
- gi|30064242|ref|NP_838413.1| putative transcriptional regulator [Shigella flexneri 2a str. 2457T]
- gi|75515287|ref|ZP_00737471.1|_2:168 COG3722: Transcriptional regulator [Escherichia coli 53638]
- gi|75196880|ref|ZP_00706950.1| COG3722: Transcriptional regulator [Escherichia coli HS]
- gi|26109755|gb|AAN81960.1|_2:168 Hypothetical protein yggD [Escherichia coli CFT073]
- gi|26249347|ref|NP_755387.1| Hypothetical protein yggD [Escherichia coli CFT073]
- gi|75258533|ref|ZP_00729955.1|_2:168 COG3722: Transcriptional regulator [Escherichia coli E22]
- gi|75228601|ref|ZP_00715230.1| COG3722: Transcriptional regulator [Escherichia coli B7A]
- gi|75212453|ref|ZP_00712477.1| COG3722: Transcriptional regulator [Escherichia coli B171]
- gi|91212310|ref|YP_542296.1|_2:168 putative transcriptional regulator [Escherichia coli UTI89]
- gi|91073884|gb|ABE08765.1| putative transcriptional regulator [Escherichia coli UTI89]
- gi|75241273|ref|ZP_00725135.1|_2:168 COG3722: Transcriptional regulator [Escherichia coli F11]
- gi|15803468|ref|NP_289501.1|_2:168 putative transcriptional regulator [Escherichia coli O157:H7 EDL933]
- gi|15833059|ref|NP_311832.1| putative transcriptional regulator [Escherichia coli O157:H7 str. Sakai]
- gi|13363277|dbj|BAB37228.1| putative transcriptional regulator [Escherichia coli O157:H7 str. Sakai]
- gi|12517469|gb|AAG58060.1| putative transcriptional regulator [Escherichia coli O157:H7 EDL933]
- gi|82778302|ref|YP_404651.1|_2:168 putative transcriptional regulator [Shigella dysenteriae Sd197]
- gi|81242450|gb|ABB63160.1| putative transcriptional regulator [Shigella dysenteriae Sd197]
- gi|28805351|dbj|BAC58631.1|_4:172 mannitol operon repressor [Vibrio parahaemolyticus RIMD 2210633]
- gi|28897142|ref|NP_796747.1| mannitol operon repressor [Vibrio parahaemolyticus RIMD 2210633]
- gi|75854725|ref|ZP_00762401.1|_4:172 COG3722: Transcriptional regulator [Vibrio sp. Ex25]
- gi|91227137|ref|ZP_01261621.1|_4:172 mannitol operon repressor [Vibrio alginolyticus 12G01]
- gi|91188789|gb|EAS75076.1| mannitol operon repressor [Vibrio alginolyticus 12G01]
- gi|37197427|dbj|BAC93267.1|_9:176 mannitol operon repressor [Vibrio vulnificus YJ016]
- gi|37678687|ref|NP_933296.1| mannitol operon repressor [Vibrio vulnificus YJ016]
- gi|27360216|gb|AAO09153.1|_5:172 Mannitol operon repressor [Vibrio vulnificus CMCP6]
- gi|27364098|ref|NP_759626.1| Mannitol operon repressor [Vibrio vulnificus CMCP6]
- gi|16131472|ref|NP_418058.1|_26:187 DNA-binding repressor [Escherichia coli K12]
- gi|1790029|gb|AAC76625.1| DNA-binding repressor [Escherichia coli K12]
- gi|26110669|gb|AAN82854.1| Mannitol operon repressor [Escherichia coli CFT073]
- gi|91213112|ref|YP_543098.1| mannitol operon repressor [Escherichia coli UTI89]
- gi|91074686|gb|ABE09567.1| mannitol operon repressor [Escherichia coli UTI89]
- gi|26250240|ref|NP_756280.1| Mannitol operon repressor [Escherichia coli CFT073]
- gi|89110411|ref|AP_004191.1| DNA-binding transcriptional repressor [Escherichia coli W3110]
- gi|82545961|ref|YP_409908.1| repressor for mtl [Shigella boydii Sb227]
- gi|466739|gb|AAB18578.1| mtlR [Escherichia coli]
- gi|84028152|sp|P0AF10|MTLR_ECOLI Mannitol operon repressor (Mannitol repressor protein) [Taxonomy]
- gi|85676442|dbj|BAE77692.1| DNA-binding transcriptional repressor [Escherichia coli W3110]
- gi|84028151|sp|P0AF11|MTLR_ECOL6 Mannitol operon repressor (Mannitol repressor protein) [Taxonomy]
- gi|434583|gb|AAA92662.1| mannitol repressor [Taxonomy]
- gi|75514332|ref|ZP_00736640.1| COG3722: Transcriptional regulator [Escherichia coli 53638]
- gi|75242616|ref|ZP_00726360.1| COG3722: Transcriptional regulator [Escherichia coli F11]
- gi|75197508|ref|ZP_00707578.1| COG3722: Transcriptional regulator [Escherichia coli HS]
- gi|75179768|ref|ZP_00699755.1| COG3722: Transcriptional regulator [Shigella boydii BS512]
- gi|83588547|ref|ZP_00927171.1| COG3722: Transcriptional regulator [Escherichia coli 101-1]
- gi|81247372|gb|ABB68080.1| repressor for mtl [Shigella boydii Sb227]
- gi|15804142|ref|NP_290181.1|_26:187 repressor for mtl [Escherichia coli O157:H7 EDL933]
- gi|15833731|ref|NP_312504.1| repressor for mtl [Escherichia coli O157:H7 str. Sakai]
- gi|74314165|ref|YP_312584.1| repressor for mtl [Shigella sonnei Ss046]
- gi|13363952|dbj|BAB37900.1| repressor for mtl [Escherichia coli O157:H7 str. Sakai]
- gi|12518345|gb|AAG58745.1| repressor for mtl [Escherichia coli O157:H7 EDL933]
- gi|75255817|ref|ZP_00727563.1| COG3722: Transcriptional regulator [Escherichia coli E22]
- gi|75237541|ref|ZP_00721574.1| COG3722: Transcriptional regulator [Escherichia coli E110019]
- gi|75228664|ref|ZP_00715285.1| COG3722: Transcriptional regulator [Escherichia coli B7A]
- gi|75211356|ref|ZP_00711455.1| COG3722: Transcriptional regulator [Escherichia coli B171]
- gi|75188364|ref|ZP_00701631.1| COG3722: Transcriptional regulator [Escherichia coli E24377A]
- gi|83571591|ref|ZP_00923031.1| COG3722: Transcriptional regulator [Shigella dysenteriae 1012]
- gi|73857642|gb|AAZ90349.1| repressor for mtl [Shigella sonnei Ss046]
- gi|77973742|ref|ZP_00829287.1|_6:171 COG3722: Transcriptional regulator [Yersinia frederiksenii ATCC 33641]
- gi|24054101|gb|AAN45082.1|_26:187 repressor for mtl [Shigella flexneri 2a str. 301]
- gi|24114865|ref|NP_709375.1| repressor for mtl [Shigella flexneri 2a str. 301]
- gi|30043386|gb|AAP19107.1| repressor for mtl [Shigella flexneri 2a str. 2457T]
- gi|30065125|ref|NP_839296.1| repressor for mtl [Shigella flexneri 2a str. 2457T]
- gi|77960732|ref|ZP_00824591.1|_6:170 COG3722: Transcriptional regulator [Yersinia mollaretii ATCC 43969]
- gi|62182181|ref|YP_218598.1|_27:188 repressor for mtl [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
- gi|62129814|gb|AAX67517.1| repressor for mtl [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]
- gi|77959633|ref|ZP_00823651.1|_6:170 COG3722: Transcriptional regulator [Yersinia bercovieri ATCC 43970]
- gi|5566392|gb|AAD45387.1|_26:187 mtl operon repressor [Klebsiella pneumoniae]
- gi|77978092|ref|ZP_00833526.1|_6:170 COG3722: Transcriptional regulator [Yersinia intermedia ATCC 29909]
- gi|16766972|ref|NP_462587.1|_27:188 mannitol operon repressor [Salmonella typhimurium LT2]
- gi|16762622|ref|NP_458239.1| mannitol operon repressor (mannitol repressor protein) [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
- gi|29144111|ref|NP_807453.1| mannitol operon repressor [Salmonella enterica subsp. enterica serovar Typhi Ty2]
- gi|16422253|gb|AAL22546.1| repressor for mtl [Salmonella typhimurium LT2]
- gi|16504927|emb|CAD03307.1| mannitol operon repressor (mannitol repressor protein) [Salmonella enterica subsp. enterica serovar Typhi]
- gi|29139748|gb|AAO71313.1| mannitol operon repressor [Salmonella enterica subsp. enterica serovar Typhi Ty2]
- gi|25513043|pir||AG0976 mannitol operon repressor (mannitol repressor protein) [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) [Taxonomy]
- gi|45438571|gb|AAS64117.1|_6:170 mannitol operon repressor [Yersinia pestis biovar Medievalis str. 91001]
- gi|108809007|ref|YP_652923.1| mannitol operon repressor [Yersinia pestis Antiqua]
- gi|108813873|ref|YP_649640.1| mannitol operon repressor [Yersinia pestis Nepal516]
- gi|108780920|gb|ABG14978.1| mannitol operon repressor [Yersinia pestis Antiqua]
- gi|108777521|gb|ABG20040.1| mannitol operon repressor [Yersinia pestis Nepal516]
- gi|21961097|gb|AAM87628.1| repressor for mtl [Yersinia pestis KIM]
- gi|51591487|emb|CAH23158.1| mannitol operon repressor [Yersinia pseudotuberculosis IP 32953]
- gi|15981961|emb|CAC93520.1| mannitol operon repressor [Yersinia pestis CO92]
- gi|22127954|ref|NP_671377.1| repressor for mtl [Yersinia pestis KIM]
- gi|51598205|ref|YP_072396.1| mannitol operon repressor [Yersinia pseudotuberculosis IP 32953]
- gi|45443701|ref|NP_995240.1| mannitol operon repressor [Yersinia pestis biovar Medievalis str. 91001]
- gi|16124180|ref|NP_407493.1| mannitol operon repressor [Yersinia pestis CO92]
- gi|89105246|ref|ZP_01177769.1| COG3722: Transcriptional regulator [Yersinia pestis biovar Orientalis str. IP275]
- gi|77634204|ref|ZP_00796310.1| COG3722: Transcriptional regulator [Yersinia pestis Angola]
- gi|77630984|ref|ZP_00793570.1| COG3722: Transcriptional regulator [Yersinia pseudotuberculosis IP 31758]
- gi|75831881|ref|ZP_00761141.1|_4:171 COG3722: Transcriptional regulator [Vibrio cholerae MO10]
- gi|75825111|ref|ZP_00754547.1| COG3722: Transcriptional regulator [Vibrio cholerae O395]
- gi|75820767|ref|ZP_00750807.1| COG3722: Transcriptional regulator [Vibrio cholerae V51]
- gi|75816617|ref|ZP_00747082.1| COG3722: Transcriptional regulator [Vibrio cholerae V52]
- gi|9658491|gb|AAF96941.1|_21:188 mannitol operon repressor [Vibrio cholerae O1 biovar eltor str. N16961]
- gi|15601798|ref|NP_233429.1| mannitol operon repressor [Vibrio cholerae O1 biovar eltor str. N16961]
- gi|75178830|ref|ZP_00698866.1|_3:147 COG3722: Transcriptional regulator [Shigella boydii BS512]
- gi|90411409|ref|ZP_01219420.1|_6:171 putative mannitol operon repressor [Photobacterium profundum 3TCK]
- gi|90327622|gb|EAS43965.1| putative mannitol operon repressor [Photobacterium profundum 3TCK]
- gi|54302041|ref|YP_132034.1|_6:171 putative mannitol operon repressor [Photobacterium profundum SS9]
- gi|46915462|emb|CAG22234.1| putative mannitol operon repressor [Photobacterium profundum SS9]
- gi|49609576|emb|CAG73009.1|_30:194 mannitol operon repressor [Erwinia carotovora subsp. atroseptica SCRI1043]
- gi|50119050|ref|YP_048217.1| mannitol operon repressor [Erwinia carotovora subsp. atroseptica SCRI1043]
- gi|84778514|dbj|BAE73291.1|_33:196 mannitol operon repressor [Sodalis glossinidius str. 'morsitans']
- gi|85057994|ref|YP_453696.1| mannitol operon repressor [Sodalis glossinidius str. 'morsitans']
- gi|77972604|ref|ZP_00828166.1|_3:167 COG3722: Transcriptional regulator [Yersinia frederiksenii ATCC 33641]
- gi|46156275|ref|ZP_00133149.2|_4:165 COG3722: Transcriptional regulator [Haemophilus somnus 2336]
- gi|106883861|ref|ZP_01351253.1|_9:173 Mannitol repressor [Psychromonas ingrahamii 37]
- gi|106761070|gb|EAT17962.1| Mannitol repressor [Psychromonas ingrahamii 37]
- gi|53692704|ref|ZP_00347400.1|_4:165 COG3722: Transcriptional regulator [Haemophilus somnus 129PT]
- gi|86144868|ref|ZP_01063200.1|_23:189 putative mannitol operon repressor [Vibrio sp. MED222]
- gi|85837767|gb|EAQ55879.1| putative mannitol operon repressor [Vibrio sp. MED222]
- gi|12721399|gb|AAK03147.1|_5:166 Mtl [Pasteurella multocida subsp. multocida str. Pm70]
- gi|15602928|ref|NP_246000.1| Mtl [Pasteurella multocida subsp. multocida str. Pm70]
- gi|75855358|ref|ZP_00763011.1|_4:167 COG3722: Transcriptional regulator [Vibrio sp. Ex25]
- gi|28808669|dbj|BAC61846.1|_4:167 putative transcriptional regulator [Vibrio parahaemolyticus RIMD 2210633]
- gi|28900358|ref|NP_800013.1| putative transcriptional regulator [Vibrio parahaemolyticus RIMD 2210633]
- gi|41419|emb|CAA32601.1|_3:132 unnamed protein product [Escherichia coli]
- gi|59713246|ref|YP_206021.1|_7:167 transcriptional regulator [Vibrio fischeri ES114]
- gi|59481494|gb|AAW87133.1| transcriptional regulator [Vibrio fischeri ES114]
- gi|84386268|ref|ZP_00989297.1|_23:188 putative mannitol operon repressor [Vibrio splendidus 12B01]
- gi|84379038|gb|EAP95892.1| putative mannitol operon repressor [Vibrio splendidus 12B01]
- gi|106882917|ref|ZP_01350317.1|_9:173 Mannitol repressor [Psychromonas ingrahamii 37]
- gi|106761892|gb|EAT18776.1| Mannitol repressor [Psychromonas ingrahamii 37]
- gi|53729271|ref|ZP_00348358.1|_5:168 COG3722: Transcriptional regulator [Actinobacillus pleuropneumoniae serovar 1 str. 4074]

              10        20        30        40        50        60     
              |         |         |         |         |         |     
   1 MATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   2 -AKLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   3 -ATLTEDDVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   4 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   5 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   6 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   7 -ATLTEDDVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   8 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGICQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
   9 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
  10 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
  11 -ATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
  12 -ATLSEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEESVEYAVKPLLAQSGPLD
  13 -ATLTEDDVLEQLDAQDNLFSFMNTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
  14 --NINESEIIERLNSAPSVRGFFIATVDVFNESIDGLIQRIFRKDN-FAVQSVVGPLLQDSGPLG
  15 --NINETEIIERLNSAPSVRGFFIAAVDVFNDSIDGLIQRIFRKDN-FAVQSVVGPLLQDSGPLG
  16 --NINETEIIERLNSAPSVRGFFIAAVDVFNDSIDGLVQRIFRKDN-FAVQSVVGPLLQDSGPLG
  17 ---TNESDIIERLNHAPSVRGFFVETVDILTEAVDGLVQRIFRKDN-FAVQSVVGPLLQDSGPLG
  18 ---TNESDIIERLNHAPSVRGFFVETVDILTEAVDGLVQRIFRKDN-FAVQSVVGPLLQDSGPLG
  19 --QAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDD-YAVKYAVEPLLDGDGPLG
  20 --QAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDD-YAVKYAVEPLLDGDGPLG
  21 --QAFENRVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVFRKDD-YAVKYAVEPLLVGDGPLG
  22 --QAVENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDD-YAVKYAVEPLLDGDGPLG
  23 --QAFENRVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVFRKDD-YAVKYAVEPLLVGDGPLG
  24 --QAFENRVLERLNAGKTVRSFLITAVELLTEAVNILVLQVFRKDD-YAVKYAVEPLLDGDGPLG
  25 --QAFENRVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVFRKDD-YAVKYAVEPLLVGDGPLG
  26 --QAFENRVLERLNAGKTVRSFLIATVELLTEAVNILVLQVFRKDD-YAVKYAVEPLLEGSGPLG
  27 --QAFENRVLEHLNAGKTVRSFLMAAVELLAEALNILVVQVFRKDD-YAVKYAVEPLLVGDGPLG
  28 --QAFENRVLERLNAGKTVRSFLITAVELLTEAVNILVLQVFRKDD-YAVKYAVEPLLDGDGPLG
  29 --QAFENRVLEHLNAGKTVRSFLMAAVDLLAEALNILVVQIFRKDD-YAVKYAVEPLLVGDGPLS
  30 --KINESDILERLNQTHTVRGFFITTVDVLTEAIDALMQRIFRKDN-FAVKSVVEPLLHDTGPLG
  31 --KINESDILERLNQTHTVRGFFITTVDVLTEAIDALMQRIFRKDN-FAVKSVVEPLLHDTGPLG
  32 ------------------------TAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
  33 ----QESDILERLSDTSNVRGFIITSVEVFEEAVDSLIQRVFRKDD-FAVKSVVGPLLDNSGPLG
  34 ----QESDILERLSDTSNVRGFIITSVEVFEEAVDSLIQRIFRKDD-FAVKSVVGPLLDNSGPLG
  35 --QAFENRVLEALNSGKTVRDFMLCAVELLAEAASILMLQVFRKDD-YAVKYAVEPLMTGTGPLG
  36 --QLLENSVLERLNAGTTVREFLRAAITLLAEAVAILVTQVFRKDD-YAVKYAVEPLLVGAGPLV
  37 --ALTEDDVLERLASPENLNDFLLNANEILFQGIKSLLPYLFINNDEDIQEYAVKPLLAKSGPLD
  38 -----EDPIYEKLNSTVSVRGFMIATVAIFEEAVDSLINRVFRKTD-FVVQSVIDSLFTNDGPLG
  39 ----FDIDIVETLSEAETPYDFFTASFDLFEDAVDILIQNVFRKDD-YAVKYAVEPLLSRDGPLA
  40 -----EDPIYEKLNGTVSVRGFMIAIVAIFEEAVDSLINRVFRKTD-FVVQSVIDSLFTNDGPLG
  41 --TTHESELLEELAESADAAECLLCAYDVLEDMLDALLKSIFYKDD-YAVKFVVDPLLTTDGPLG
  42 ------DPIYEKLNEATSIRGFITASVAIFDEAVDKLINRVFRKTD-FAVKSVVDSLLSNSGPLC
  43 -----EDELLEKLDECENATAFLQVSNKIINLKLKALLPSVFVQDD-LVKEYAVDPLLKEDGPLV
  44 -----EDELLEKLDECENATAFLQVSNKIINLKLKALLPSVFVQDD-LVKEYAVDPLLREDGPLV
  45 ------------------------TAHTILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLD
  46 --------LLETVEECDDATSFLCASNKLINLKLKALLPNIFVQDE-LVMEYAVEPLLKEDGPLV
  47 --TSHETELLEALSEAESASACLMAAYDALDDTVDAVLKNIFKKDD-TAIKFVVEPLLNSGGPLG
  48 ----FDIDIVETLSEAETAYVFFTASFDLFEDAIDILIQNVFRKDD-YAVKYAVEPLLNNDGPLA
  49 ------DNFIEQLSEVPSLRGFFALSVNQFAQNIERLIQRVFRKTD-FALKSVVDSLFEHQGPLA


         70        80        90       100       110       120          
         |         |         |         |         |         |          
   1 DIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFADDITWDFISNVNSI..TRNATL
   2 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TRNAML
   3 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TRNAML
   4 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TRNATL
   5 DIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFADDMTWDFISNVNSI..TCNATL
   6 DIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFADDITWDFISNVNSI..TRNATL
   7 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TCNATL
   8 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDITWDFISNVNSI..TRNATL
   9 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TCNATL
  10 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMAWDFISNVNSI..IRNASL
  11 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQNEMPGFADDMAWDFISNVNSI..TRNATL
  12 DIDVALRLIYALGKMDKWLYADITHFSQYWHYLKEQDETLGFADDMTWDFISNVNSI..TCNATL
  13 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TCNATL
  14 DLSVRLKLLFGLGVLPDDIYHDIEDIIKLKNHLNSDASDYEFTDPNILEPIKKLHLV..KKMGMV
  15 DLSVRLKLLFGLGVLPDDIYHDIEDIIKLKNRLNSDASDYEFTDPNILEPIKKLHLV..KKMGMV
  16 DLSVRLKLLFGLGVLPDDIYHDIEDIIKLKNQLNSDASDYEFTDPNILEPIKKLHLV..KKMGMV
  17 DVSVRLKLLFGLGVLSDHHYHDIEDIIKLKNKLNSDSTEYEFTDPQILEPIKKLHLV..QKMGMV
  18 DVSVRLKLLFGLGVLSDHHYHDIEDIIKLKNKLNSDSTEYEFTDPQILEPIKKLHLV..QKMGMV
  19 DLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCV..AALPP-
  20 DLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCV..AALPP-
  21 ELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCV..AELPPA
  22 DLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCV..AALPP-
  23 ELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCV..AELPPV
  24 DLSVRLKLIYGLGVLSRTEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCV..MALPP-
  25 ELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCV..VELPPV
  26 DLSVRLKLIYGLGVISRAEYEDAELLMALREELNHDGNEYSFTDDEIIGPFGELHCV..AALPP-
  27 ELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCV..AELPPV
  28 DLSVRLKLIYGLGVLSRTEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCV..MALPP-
  29 ELSVRLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCV..DELPPV
  30 DLTVRLKLLFGLGVIPDEVFHDIEHLIKLRNQLNHDATEYQFTDPQILAPIKALNLV..KKMGML
  31 DLTVRLKLLFGLGVIPDEVFHDIEHLIKLRNQLNHDATEYQFTDPQILAPIKALNLV..KKMGML
  32 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TRNAML
  33 EITVRLKLLLGLGVVSHNIYQDIDAFLKLRDFLNSDGNDYCFTDPKILQPIKKMHAV..QNMGVV
  34 EITVRLKLLLGLGVVSHNIYQDIDAFLKLRDFLNSDGSDYCFTDPKILQPIKKMHAV..QNMGVV
  35 DLSVRLKLIYGLGMISRKEYEDAELLMALGEELAHDDRHYRFTDDEILGPIGELHCV..AALPAE
  36 ELSVRLKLVYALGVISRQEYEDAELLMALHEELKQDPGDYRFTDDEILGPFGELHCV..AAFPPS
  37 SLDVSLRLIYALGQITKAVYADILLFSQLSEHLQETGEIAEFHDDIVYEFMGNLNAV..TQNKTL
  38 DLSVRLKVLLGLGVIQHNLFSDVNAFIQFKETLNKDEKEYTFDDEIVLTFLQKLTLL..MDKSAL
  39 HLPVRIKLLYGLGLLSQGSYQDIEKFIGLKEFVQSEGESIEFLSLALIERLNAIRAV..AKILPP
  40 DLSVRLKVLLGLGVIQHNLFSDVNAFIQFKETLNKDEKEYTFDDEIVLTFLQKLTLL..MDKSAL
  41 EILVRTKLLLGLGVISKEVYDDIEVFVTLKEWVNIQEGQVNFWDQDVVFELNRINAI..QKMMPI
  42 DLSIRLKVLLGLGIIEHHVFSDISHFIEIKEKLNNDEKEYDFADLIIIDFIQQLSCQ..NDKSLL
  43 TTDVVSKLMFAMGKISLETYADIGLYDQVLEYVVSQPEKVEFADDVIYDFIKNQAVLssQQDSFY
  44 TTDVVSKLMFAMGKISLQTYADIGLYDQVLEYVVTQPEKIAFTDDVIYDFIKNQAVLssQQDCFY
  45 DIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSI..TRNAML
  46 TTDVVSKLMFAMGKISLETYADIGLYAQVLEYAQSQPNKLSFGDDMIYDFISNQAVLstQQDSFY
  47 EIMIRAKLLLGLGVISKELYDDLEIFVTLKEWAKIQGEDTSFTEVDVIFELNKVQAI..QRIMPI
  48 QLAIRIKLLYGLGLLSQDAYQDIEKFIALKTFVQSEGESIDFLSPLLFERINAISAV..AEMIPI
  49 ELTVRLKLLLGLGVISAAVFEDISLFIEVKQQLSDEVEELPFSHPAIVQFAKDLHHI..DLSPVA


         130            140       150       160         
          |              |         |         |         
   1 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELTP
   2 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTILKELTP
   3 ....YDALK..AMKFA...DFSVWSEARFSGMVKTALTLAVTTTLKELT-
   4 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
   5 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
   6 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
   7 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
   8 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
   9 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
  10 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALMLAVTTTLKELT-
  11 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
  12 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTTLKELT-
  13 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLVVTTTLKELT-
  14 ....QLEVN..EPDDDidlEFYQLQLQRQQQIIKSGLSLAIVEICNELGK
  15 ....QLEVN..EPDDDidlEFYQLQLQRQQQIIKSGLSLAIVEICNELGK
  16 ....QLEVS..EPDDDidlEFYQLQLQRQQQIIKSGLSLAIVEICNELGK
  17 ....QLEVD..DPDDDielSFYQLQLQRKQQIIRSGLSLAIVEICHELGK
  18 ....QLEVD..DPDDDielSFYQLQLQRKQQIIRSGLSLAIVEICHELGK
  19 ....-PPQF..EPADS...SLYAMQIQRYQQAVRSTMVLSLTELISKI--
  20 ....-PPQF..EPADS...SLYAMQIQRYQQAVRSTMVLSLTELISRI--
  21 ....PTFLRp.DEADA...SLIAMQRQRYQQMVRSTMVLSITELLSRIS-
  22 ....-PPQF..EPADS...SLYAMQIQRYQQAVRSTMVLSLTELISKI--
  23 ....PTFLRp.DEADA...SLIAMQRQRYQQMVRSTMVLSITELLSRI--
  24 ....-PPHF..DTSDA...ALYAMQIQRYQQAVRSTMILSLTELISKI--
  25 ....PTFLRp.DEADA...SLIAMQRQRYQQMVRSTMVLSITELLSRI--
  26 ....-TPQF..DDSDA...ELLAMQKLRYQQMVRSTMVLSLTELISRI--
  27 ....PTFLRp.DEADA...SLIAMQRQRYQQMVRSTMVLSITELLSRI--
  28 ....-PPHF..DTSDA...ALYAMQIQRYQQAVRSTMVLSLTELISKI--
  29 ....PTFLRp.DEADA...SLIAMQRQRYQQMVRSTMVLSITELLSRI--
  30 ....HLNVV..EPDDDidlSFYHLQLQRQQQVIKSGLSLAIIQICNALN-
  31 ....HLNVV..EPDDDidlSFYHLQLQRQQQVIKSGLSLAIIQICNALN-
  32 ....YDALK..AMKFA...DFAVWSEARFSGMVKTALTLAVTTILKELTP
  33 ....QLEIA..SPGDDvdlIFYQMQLARQEQIIKSALALAIAGICNELG-
  34 ....QLEIA..SPSDDvdlIFYQMQLARQEQIIKSALALAIAGICNELG-
  35 p...TLPLG..ADADP...LLVSMQQQRYQQMVRSTLVLSLTTLIAQI--
  36 ....PQISR..APEDE...ALTKMQRQRYQQMVRSTMVLSATEYLVRI--
  37 ....FQLIE..KMKFS...DFTIFNQTRYGNMVKTGLTLAVTSLLQEL--
  38 d...FEPLI..EDKNS...LTYQMKSLRREKIIRSCLILTIADIYRQL--
  39 nl..GDNQL..EESSH...YIVQMKLEQNRQVIKSSLILAITEIIKELH-
  40 d...FEPLI..EDKNS...LTYQMKSLRREKIIRSCLILTIADIYRQL--
  41 dy..APELV..EGMSD...DMKRMFLERHFQKVRSTIVLAVNDIHQQLA-
  42 ....NFPMEkdENPDS...LLYQVKALRREKLIRSYLTLAITEIYEQL--
  43 ....LESIN..QLKFS...SFESFSQMRYESLIKTVLKLSCEMLIERIE-
  44 ....LESIN..QLKFS...SFESFSQMRYESLIKTVLKLSCEMLIERIE-
  45 ....YDALK..AMKFA...DFSVWSEARFSGMVKT---------------
  46 ....LESIN..QLKFS...SFEVFSQMRYESLIKTVLKLSCEMLLEKIE-
  47 ey..DSEMV..ETMSG...PMLQMFLGRHNQKVKSTIVLAITDIITTL--
  48 na..DDNQP..EESSH...FIVQMKLDHNRQVIKSSLILAITEIIKELH-
  49 dllkFASSV..ENKDS...MLYQMQQIRLERVMRSSLILAITEINEKL--