CASP7 Target T0318

1. Protein Name
NP_498854
2. Organism Name
Caenorhabditis elegans
3. Number of amino acids (approx)
491
4. Accession number
P34629
5. Sequence Database
Swiss-prot
6. Amino acid sequence
MTQVLVRNGIQAVGDGLTSLIIVGKKSVLKNVTFEGKFKEVAQKFVTDGDSWNSMISRIP
ASGRHPLHYELAHLITVPDASSRGNTPTNAHSIYKELKPINYPEDTKNVHFVLFAEYPDV
LSHVAAIARTFCKFSMKTSGIRELNVNIDVVCDKLTNEDAVFLTDLSESVRETARLIDTP
ANILTTDALVDEAVKVGNATGSKITVIRGEELLKAGFGGIYHVGKAGPTPPAFVVLSHEV
PGSTEHIALVGKGVVYDTGGLQIKTKTGMPNMKRDMGGAAGMLEAYSALVKHGFSQTLHA
CLCIVENNVSPIANKPDDIIKMLSGKTVEINNTDAEGRLILADGVFYAKETLKATTIFDM
ATLTGAQAWLSGRLHGAAMTNDEQLENEIIKAGKASGDLVAPMLFAPDLFFGDLKSSIAD
MKNSNLGKMDGPPSAVAGLLIGAHIGFGEGLRWLHLDIAAPAEVGDRGTGYGPALFSTLL
GKYTSVPMLKQ
7. Additional information
pH of crystals 8.5
likely homodimer in solution, but arrangement in the crystal is hexameric,
no S-S bridges, predicted metal-binding site is occupied by water,
note, that there is a point mutation as compared to the sequence from the database, Phe440 is replaced by Leu in te sequence provided above
The initial Met is processed
8. X-ray structure
yes
9. Current state of the experimental work
solved and refined, resolution is 2A, Rwork ~15.7%, Rfree ~18.7%
10. Interpretable map?
yes
11. Estimated date of chain tracing completion
completed
12. Estimated date of public release of structure
beginning of August

Related Files

Template Sequence file

Template PDB file