CASP7 Target T0318
- 1. Protein Name
- NP_498854
- 2. Organism Name
- Caenorhabditis elegans
- 3. Number of amino acids (approx)
- 491
- 4. Accession number
- P34629
- 5. Sequence Database
- Swiss-prot
- 6. Amino acid sequence
-
MTQVLVRNGIQAVGDGLTSLIIVGKKSVLKNVTFEGKFKEVAQKFVTDGDSWNSMISRIP
ASGRHPLHYELAHLITVPDASSRGNTPTNAHSIYKELKPINYPEDTKNVHFVLFAEYPDV
LSHVAAIARTFCKFSMKTSGIRELNVNIDVVCDKLTNEDAVFLTDLSESVRETARLIDTP
ANILTTDALVDEAVKVGNATGSKITVIRGEELLKAGFGGIYHVGKAGPTPPAFVVLSHEV
PGSTEHIALVGKGVVYDTGGLQIKTKTGMPNMKRDMGGAAGMLEAYSALVKHGFSQTLHA
CLCIVENNVSPIANKPDDIIKMLSGKTVEINNTDAEGRLILADGVFYAKETLKATTIFDM
ATLTGAQAWLSGRLHGAAMTNDEQLENEIIKAGKASGDLVAPMLFAPDLFFGDLKSSIAD
MKNSNLGKMDGPPSAVAGLLIGAHIGFGEGLRWLHLDIAAPAEVGDRGTGYGPALFSTLL
GKYTSVPMLKQ
- 7. Additional information
- pH of crystals 8.5
likely homodimer in solution, but arrangement in the crystal is hexameric,
no S-S bridges, predicted metal-binding site is occupied by water,
note, that there is a point mutation as compared to the sequence from the database, Phe440 is replaced by Leu in te sequence provided above
The initial Met is processed
- 8. X-ray structure
- yes
- 9. Current state of the experimental work
- solved and refined, resolution is 2A, Rwork ~15.7%, Rfree ~18.7%
- 10. Interpretable map?
- yes
- 11. Estimated date of chain tracing completion
- completed
- 12. Estimated date of public release of structure
- beginning of August
Related Files
Template Sequence file Template PDB file