CreatePredAlphaCost pred_alpha2k alpha11 T0272.t2k.alpha.rdb 2 alpha alpha_prev sum
CreatePredAlphaCost pred_alpha04 alpha11 T0272.t04.alpha.rdb 2 alpha alpha_prev sum

SetCost wet6.5 5 near_backbone 5 way_back 5 dry5 15 dry6.5 20 dry8 15 dry12 5 \
	phobic_fit 2 \
	sidechain 1 \
	bystroff 5 \
	soft_clashes 10  backbone_clashes 2 \
	break 20  \
	pred_alpha2k 2 \
	pred_alpha04 4 \
	constraints 10 \
	hbond_geom 1 \
	hbond_geom_backbone 1 \
	hbond_geom_beta 5 \
	hbond_geom_beta_pair 10

// Add the following for extra-cellular proteins:
#	known_ssbond 0.5	# and put ssbond command in constraints file
#	maybe_ssbond 0.5

// For comparative modeling, increase weight of break and hbond_geom...

// put any constraints here, such as helix constraints, strand constraints,
//	sheet constraints, ssbonds, hbonds, or just arbitrary pairs of atoms.

#from T0272.t2k.dssp-ehl2.constraints
# HelixConstraint 	A15	D18	0.7007
# HelixConstraint 	P22	A32	0.6534
# HelixConstraint 	P119	E132	0.7646
# HelixConstraint 	D151	L154	0.6004
# HelixConstraint 	P185	R193	0.8437
# 
# StrandConstraint	L3	V7	0.689
# StrandConstraint	L45	R47	0.7465
# StrandConstraint	V58	Q62	0.8361
# StrandConstraint	Q78	V79	0.6982
# StrandConstraint	R94	A101	0.7432
# StrandConstraint	L168	V182	0.7284

# from T0272.t04.dssp-ehl2.constraints
HelixConstraint 	S12	D18	0.6372
HelixConstraint 	P22	V33	0.6279
HelixConstraint 	E121	R129	0.6312
HelixConstraint 	W145	Q147	0.6048
HelixConstraint 	T152	F153	0.6268
HelixConstraint 	P185	R193	0.8923

StrandConstraint	W2	V7	0.7252
StrandConstraint	L44	R47	0.7005
StrandConstraint	V58	Q62	0.8486
StrandConstraint	R94	A101	0.7096
StrandConstraint	K105	L107	0.63
StrandConstraint	R113	A115	0.662
StrandConstraint	L168	F176	0.8143
StrandConstraint	R179	V182	0.7871
StrandConstraint	L206	S208	0.6499

# from T0272.t04.aplha.constraints
HelixConstraint 	R13	R16	0.647
HelixConstraint 	Y23	A32	0.645
HelixConstraint 	V123	R128	0.721
HelixConstraint 	W145	L149	0.607
HelixConstraint 	E186	R193	0.786

StrandConstraint	W2	L3	0.627
StrandConstraint	K5	V7	0.697
StrandConstraint	L44	W46	0.635
StrandConstraint	P57	V61	0.755
StrandConstraint	R94	R100	0.799
StrandConstraint	L168	V171	0.783
StrandConstraint	A173	L175	0.797
StrandConstraint	L180	V182	0.676
StrandConstraint	L206	S208	0.61

# file generated by validate2rr
# based on 280 inputs
# using the NN280-240n300.net.28 network
# limited to score of .30 or greater.
# The score is an approximation of the probability
Constraint L29.CB L95.CB -10. 7.0 14.0 0.517 
Constraint V59.CB L99.CB -10. 7.0 14.0 0.361 
Constraint V182.CB L206.CB -10. 7.0 14.0 0.329 bonus
Constraint L99.CB L192.CB -10. 7.0 14.0 0.3 bonus

# another long shot - constraints from thin35
Constraint E132.CB Q147.CB -10. 7.0 12.0 0.661735
Constraint Y76.CB A109.CB -10. 7.0 12.0 0.640172
Constraint E39.CB P50.CB -10. 7.0 12.0 0.551715
Constraint W145.CB K159.CB -10. 7.0 12.0 0.546168