CreatePredAlphaCost pred_alpha2k alpha11 T0251.t2k.alpha.rdb 2 alpha alpha_prev sum
CreatePredAlphaCost pred_alpha04 alpha11 T0251.t04.alpha.rdb 2 alpha alpha_prev sum

SetCost wet6.5 3 near_backbone 3 way_back 3 dry5 5 dry6.5 6 dry8 5 dry12 2 \
	phobic_fit 2 \
	sidechain 6 \
	bystroff 5 \
	soft_clashes 10  backbone_clashes 2 \
	break 20  \
	pred_alpha2k 3 \
	pred_alpha04 3 \
	constraints 10 \
	hbond_geom 1 \
	hbond_geom_backbone 1 \
	hbond_geom_beta 5 \
	hbond_geom_beta_pair 10

// Add the following for extra-cellular proteins:
#	known_ssbond 0.5	# and put ssbond command in constraints file
#	maybe_ssbond 0.5

// For comparative modeling, increase weight of break and hbond_geom...

// put any constraints here, such as helix constraints, strand constraints,
//	sheet constraints, ssbonds, hbonds, or just arbitrary pairs of atoms.

# from t04.dssp-ehl2
StrandConstraint	V2	Y4	0.7157
StrandConstraint	V8	I9	0.6778
HelixConstraint 	S19	R32	0.6327
StrandConstraint	F39	D45	0.773
HelixConstraint 	D57	E65	0.6137
StrandConstraint	L73	M76	0.7471
HelixConstraint 	K89	L99	0.6494

# from try1-opt2
SheetConstraint (T0251)M1 (T0251)Y4	(T0251)Y85 (T0251)A82	hbond (T0251)V3
SheetConstraint (T0251)P72 (T0251)T75	(T0251)G84 (T0251)V81	hbond (T0251)I74
SheetConstraint (T0251)I74 (T0251)M76	(T0251)V81 (T0251)E79	hbond (T0251)M76

SheetConstraint M1 D7	F39 D45		3.0

Constraint C10.SG C13.SG	-10 3.5 7	1.0