(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • T0250 NP_375720, Staphylococcus aureus subsp. aureus N315 
                              10        20        30        40        5
                              |         |         |         |         
   1 ...M...T...N..V.....LYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDGEVIFL
   2 rtkM...S...N..E.....VYQTSTMLALLDGIYDGVISFEELKEHGDFGIGTFDQLDGEMIAF
   3 rtkT...N...N..E.....VYQTSTMLALLDGIYDGVISFEELKERGDFGIGTFDQLDGEMIAF
   4 rtkM...N...N..E.....VYQTSTMLALLDGIYDGVISFEELKERGDFGIGTFDQLDGEMIAF
   5 ktkT...S...N..E.....VYQTSTMLALLDGIYDGVISFEDLKKHGDFGIGTFDQLDGEMIAF
   6 ktkT...S...N..E.....VYQTSTMLALLDGIYDGVISFEDLKKHGDFGIGTFDQLDGEMIAF
   7 ...M...T...N..V.....LYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDGEVIFL
   8 ...M...T...N..V.....LYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDGEVIFL
   9 ...M...A...S..V.....LYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFL
  10 ...M...A...S..V.....LYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFL
  11 ...M...T...N..V.....LYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFL
  12 ...M...T...N..V.....LYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDGEVIFL
  13 ...M...A...S..V.....LYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFL
  14 ...M...T...N..V.....LYQHGTLGTLMAGLLEGTASINDLLEHGDLGIATLTGSDGEVIFV
  15 ...M...S...E..Itq...LFQYNTLGALMAGLYEGTMTIGELLKHGDLGIGTLDSIDGELIVL
  16 ...M...T...E..Itq...LFQYNTLGALMAGLYEGTMTIGELLKHGDLGIGTLDSVDGELIVL
  17 akhP...D...S..V.....IYQTSLMSALLSGVYEGDTTIADLLAHGDFGLGTFNELDGEMIAF
  18 ...M...Et..N..K.....LFQYNTLGALMAGLYDGSLTVGELLEYGDLGLGTLDSIDGELIVL
  19 ahhP...D...S..V.....IYQTSLMSALLSGVYEGSTTIADLLTHGDFGLGTFNELDGELIAF
  20 dtvR...K...N..R.....LFQHSTMAALVGGLFSGTTSFKELLQHGDLGIGTLDQFDGELIIL
  21 dtvR...K...N..R.....LFQHSTMAALVGGLFSGTTSFKELLQHGDLGIGTLDQFDGELIIL
  22 davR...K...N..R.....LFQHSTMAALVGGLFSGTTSFKELLQHGDLGIGTLDQFDGELIIL
  23 ...M...S...EaiK.....LFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSIDGELIVL
  24 ...-...K...N..VqepvkLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVL
  25 ...-...K...N..VqepvkLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVL
  26 aqhP...D...S..V.....IYQTSLMSALLSGVYVGETTIADLLAHGDFGLGTFNELDGEMIAF
  27 ...Mt..E...K..I.....LYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLDGEVIFL
  28 kdqP...V...S..Q.....IYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLDGELIGF
  29 ...M...S...E..Tvk...LFQYSTLSSLMAGLYKGSLTIGELLTHGDLGIGTVHMIDGELIVL
  30 ...M...S...E..Tvk...LFQYSTLSSLMAGLYKGSLTIGELLTHGDLGIGTVHMIDGELIVL
  31 snnA...S...D..V.....LYQVSTIDALLLGVYDGVLPVSDLKTHGDFGIGTFDGLEGEMLAL
  32 qehA...D...C..V.....IYQTSLMSGLINGVYEGSRTMAELLEHGDFGLGTFNSLDGELVAL
  33 hisG...E...G..E.....IYQTSLMSALIAGVYEGATTIAQLLEHGDFGLGTFNELDGELIAF
  34 seqV...S...D..V.....LYQVSTINALMESIYDGFVPVDELVTHGDFGIGTFDKLDGEMVVL
  35 davR...K...N..R.....LFQHSTMAALVGGLFSGTTSFKELLQHGDLGIGTLDQFDGELIIL
  36 eevI...P...N..H.....IYQMSTINALVSGLYDGCASLKKLLTKGDFGIGTFKDLDGELTLL
  37 thpS...Q...N..T.....IFQVATIGSLAQGVYDGDFTYGKLQKKGNFGLGTFLDLNGEMVAV
  38 m..S...E...Q..Y.....VYQHGTLGGLMESLMAGTAEIGTLLTQGDFGIGTLEGSNGEIILL
  39 ...MakyE...S..K.....VYQHGTLGMLVPGLFEGTMTVADLLKHGDWGIGTASGLDGEMILL
  40 ...M...D...T..Tt....IFQHGTLGLLVPGLFDGTITAGELLTHGDTGIGTLDGLNGEVIIL
  41 ...-...M...A..K.....LFQHGTLAMLVDGLFGGTLAVSDLLKHGDFGIGTAEGLNGELIIL
  42 qytS...S...N..T.....LFQTSTISALAVGIFDGNTNFKQLRKHGNFGLGTVNALDGEMVGL
  43 vrpR...M...N..R.....LYQTSTMAALLDAVYDGETTLDELLMHGNFGLGTFNGLDGEMIVN
  44 npaP...K...N..V.....LFQYSTINALMLGQFEGDLTLKDLKLRGDMGLGTINDLDGEMIQM
  45 a..Mqh.D...D..T.....LLQISTMMALLDGVFESETRYESILPGYDFGIGTFDHLDGEMIGF
  46 ...M...K...D..Ltk...AYQHGTLAQIMDGQYDGTILLKDLLEHGDFGIGTTTGIGVELIVL
  47 ...M...K...D..Ltk...AYQHGTLAQIMDGQYDGTILLKDLLEHGDFGIGTTTGIGVELIVL
  48 llaE...R...H..T.....IFQSSLMTALLDGIYDGEISIGELLGHGNFGIGTFDALDGEMVIL
  49 ...MrqnM...T..T.....IYQHGTLAQLVARQMSGTITVAEMLEHGDTGIGTFEGLNGEAIFL
  50 akhP...D...S..V.....IYQTSIMSALLSGVYERDTTIADLLAHGDFGLGTFNELDGEMIAF
  51 ...Ma..Q...N..E.....VFQYSLISALMDGVATHGTPISRVLDHGDHGLGTFKSMNGEMIVL
  52 thpS...Q...N..T.....IFQVATIGS-RARCLRWRFYYGKLQKKGNFGLGTFLDLNGEMVAV
  53 ...-...M...S..T.....IYQHGTLELIMSGLYDGTAPLSSILNHGSSGIGTMDELDGEVTII
  54 sqdN...N...D..V.....VFTASISTAIYSALYDGVVTYGMLKRFGDMGLGAPDRIDGEMFAV
  55 pkmP...S...N..H.....LFQYSVVSALMDGVAETGITISDLLKYGDHGLGTFRHMVGEMIIL
  56 nsvS...D...D..V.....VFQASTADALYSSVFDGYITYGKLKRNGDFGLGAPDHIDGEIMAI
  57 ...M...N...S..R.....IFQHNTFTTLSSGFYKGTITLKEALEHGSVGIGTLDTANGEVTII
  58 m..F...K...S..K.....AHAFSSINALSKGNYCSNFTAQEILKEGNFGIGAFESLNGELIIV
  59 ...-...-...-..-.....---------------------------------------------
  60 m..N...K...K..T.....LYQANTFATIQNKHYKGDMSLLEVLKKGKFGVGTFNYTDGEFILK
  61 ...-...-...-..-.....---------------------------------------------
  62 ...-...-...-..-.....---------------------------------------------
  63 ...-...-...-..-.....---------------------------------------------
  64 ...-...-...-..-.....---------------------------------------------
  65 ...G...NgdiD..V.....LYQVSTIDALLQGVYDGILPVAELETHGDFGIGTFDGLEGEMLAL
  66 ...-...-...-..-.....---------------------------------------------
  67 ...-...-...-..-.....---------MLQGVYEGNFSIGALETHGDFGIGTLDNLDEEMLAL


      0          60                   70         80              90    
     |           |                    |          |               |    
   1 DGKAYH.AN.EHK...EF..IELK.G.D....EKV.PYASITNFKA.S.KT..FPL.Q.QL.S.Q
   2 DNEFYH.LR.SDG...SA..EKVE.P.E....ETT.PFATVTFFEK.E.MS..YTI.ErPM.N.R
   3 DNEFYH.LR.SDG...SA..EKVE.P.E....ETT.PFATVTFFEK.E.MS..YTI.ErPM.N.R
   4 DNEFYH.LR.SDG...SA..EKVE.P.E....ETT.PFATVTFFEK.E.MS..YTI.ErPM.N.R
   5 DNEFYH.LR.SDG...SA..EKVE.P.E....ETT.PFATVTFFEK.E.MS..YTV.EhPM.N.R
   6 DNEFYH.LR.SDG...SA..EKVE.P.E....ETT.PFATVTFFEK.E.MS..YTV.ErPM.N.R
   7 DGKAYH.AN.EHK...EF..IELK.G.D....EKV.PYASITNFKA.S.KT..FSL.Q.QL.S.Q
   8 DGKAYH.AN.EHK...EF..IELK.G.D....EKV.PYASITNFKA.S.KT..FSL.Q.QL.S.Q
   9 DGKAYH.AN.EHK...EF..VELK.G.D....ELT.PYATVTKFVA.D.TS..YET.K.DK.S.S
  10 DGKAYH.AN.EHK...EF..VELK.G.D....ELT.PYATVTKFVA.D.TS..YET.K.DK.S.S
  11 DGKAYH.AN.EHK...EF..VELK.G.D....ELT.PYATVTKFVA.D.TS..YET.K.DK.S.S
  12 DGKAYH.AN.EHK...EF..IELK.G.D....EKV.PYASITNFKA.S.KT..FPL.Q.QL.S.Q
  13 DGKAYH.AN.EHK...EF..VELK.G.D....ELT.PYATVTKFVA.D.TS..YET.K.DK.S.S
  14 DGKAYH.AN.EHK...EF..IELT.G.D....EMT.PYATVTKFKA.D.SS..FKT.S.NK.N.Q
  15 DGKAYQ.AK.GDK...TI..VELT.D.D....IKV.PYAAVVPHQA.E.VV..FKQ.KfTV.S.D
  16 DGKAYQ.AK.GDK...TI..VELT.D.D....IKV.PYAAVVPHQA.E.VV..FKQ.KfTA.S.D
  17 SSQVYQ.LR.ADG...SA..RAAK.P.E....QKT.PFAVMTWFQP.Q.YR..KTF.DaPV.S.R
  18 DGKAYQ.AK.GSGdkpEV..VEVP.D.D....MKV.PYAAVIHHEA.E.VI..FKQ.RfEM.T.D
  19 SSEVYQ.LR.ADG...SA..RKAR.A.D....QKT.PFAVMTWFRP.Q.YR..KTF.DhPV.S.R
  20 DGEAFQ.IR.SDG...QA..YKVK.P.E....DTT.PYASTTFFEA.D.TS..FTVsE.PT.S.K
  21 DGEAFQ.IR.SDG...QA..YKVK.P.E....DTT.PYASTTFFDA.D.TS..FSVsE.PT.S.K
  22 DGEAFQ.IR.SDG...QA..YKVK.P.E....DTT.PYASTTFFDA.D.TS..FSVsE.PT.S.K
  23 DGKAYQ.AKgSEGkv.EV..VEVS.P.D....EKV.PYAAVVPHQA.E.VI..FRQ.RyEM.T.D
  24 DGKAYQ.AK.GSGdqpEI..VEVS.P.D....ALI.PYAAVVPHQA.E.VI..FRQ.RfEM.T.D
  25 DGKAYQ.AK.GSGdqpEI..VEVS.P.D....ALI.PYAAVVPHRA.E.VI..FRQ.RfEM.T.D
  26 SSQVYQ.LR.ADG...SA..RAAK.P.E....QKT.PFAVMTWFQP.Q.YR..KTF.NgPV.S.R
  27 DGVAYQ.GR.SDG...SV..AQLD.G.S....ELT.PYAAITDFTP.D.TS..FSVsK.TA.D.G
  28 DGEFYR.LR.SDG...TA..TPVQ.N.G....DRS.PFCSFTFFTP.D.MT..HKI.DaKM.T.R
  29 DGKAYQaIG.TDGka.EI..IQLS.D.D....VTV.PYAAVLPHHI.Q.KQ..FDI.NaEI.D.N
  30 DGKAYQaIG.TDGka.EI..IQLS.D.D....VTV.PYAAVLPHYI.Q.KQ..FDI.NaET.D.N
  31 DGNYYQ.IK.TDG...IA..YPVS.G.E....ITT.PFATVTYFEA.D.ET..FRL.EkSA.N.L
  32 NSQIFQ.LL.SDG...SA..RAAR.P.E....QKT.PFAVMTFFRP.T.ET..IRF.H.RWtS.R
  33 DRQVFQ.LR.ADG...SA..QPAH.P.E....QQT.PFAVFTFFKA.D.IE..LPItE.RM.T.R
  34 DGICYQ.VK.ADG...VA..YRV-.E.N....VTT.PFATVTSFEN.D.ET..YYL.D.NM.N.I
  35 DGEAY-.--.---...--..-KVK.P.E....DTT.PYASTTFFDA.D.TS..FSVsE.PT.S.K
  36 DGIFYR.TK.PDG...SI..YVCS.E.N....DSV.PFAVITKLEN.Y.NT..ENI.E.AC.NsY
  37 DGHYYE.IE.ANG...KL..RPVT.T.K....QIA.PFAEVTFFNP.T.IH..KTI.E.NAaN.Y
  38 DGTLYH.AN.QTG...EI..TILE.G.E....ELT.PYAAVTRFQE.D.GA..FPV.S.TE.T.D
  39 DHVPYL.AQ.SNG...EI..RILK.P.E....EKV.PFATVHFEEI.K.DS..FKV.E.NL.T.Q
  40 GGHAYQ.AR.EDG...QI..REIQ.P.E....ETL.PFASVHFEKP.D.IS..AQL.A.AI.T.Q
  41 DGAPYQ.AL.ADG...TI..RVIG.D.D....ELL.PFANVNSADF.E.GR..AVL.S.DI.E.M
  42 DGKFYQ.IK.ADG...VA..SVIP.D.S....MTS.PFATVTFFQP.E.TL..INL.EgRM.N.Y
  43 DSVIHQ.FR.ADG...QA..GRVP.G.D....LRT.PFACVTFFNP.E.KE..YMI.D.TA.Q.D
  44 GTKFYQ.ID.STG...KL..SELP.E.S....VKT.PFAVTTHFEP.K.EK..TTL.T.NVqD.Y
  45 DGSFYQ.LR.SDG...SA..RPLD.L.K....TTT.PFCSLTRFVP.E.QS..LSV.KqTM.S.K
  46 DGVAYG.IP.SSG...KV..QKMDiE.H....EKA.PFANINYFDQ.KlKS..ESL.I.NL.D.S
  47 DGVAYG.IP.SSG...KV..QKMDiE.H....EKA.PFANINYFDQ.KlKS..ETL.I.NL.D.S
  48 DGVCYQ.LR.GDG...SA..SEAA.L.T....QRS.PFAIATNFVP.R.LK..ARVpR.GM.H.R
  49 NGEAYQ.AD.STG...KV..HHIT.D.K....QTTlPFASIHFDQP.E.ASqkLPF.K.KI.K.Y
  50 SSQVYQ.LR.ADG...SA..RAAK.P.E....QKT.PFAVMTWFQP.Q.YR..KTF.DaPV.S.R
  51 DGVCYQ.MK.SDG...TIehIHTP.S.E....VIT.PFATVTRFNP.D.VS..IRA.T.IS.N.K
  52 DGHYYE.IE.ANG...KL..RPVT.T.K....QIA.PFAEVTFFNP.T.IH..KTI.E.NAaN.Y
  53 ENSVYQ.TK.ANG...VT..KGIT.DlS....LET.PFTSIHSQSE.L.YY..FLQ.E.KF.L.T
  54 DGRFYN.IL.ADG...SI..YELA.D.S....EKA.SWATVKFFRP.D.RI..LTF.DkPI.S.C
  55 DGVLYD.MK.PDG...SV..VALD.K.DacakEIA.PFAMITEYQP.I.AT..IS-.K.EL.N.T
  56 DGKYYQ.SK.TDG...TV..RETD.D.A....ETV.SWATVKFFKP.E.KS..FDIlQ.PI.D.C
  57 NGIAYH.GD.SEN...HV..RLVE.E.D....ETM.PYVAMVEHQP.I.AK..FTD.S.SVsN.S
  58 HGKAYQ.II.DNT...NV..ILCN.S.N....VNI.SYAFVCNHDY.KgFG..YKF.E.NL.T.K
  59 ------.--.---...--..----.-.G....DLS.PFCSFTFFTP.D.MT..HTI.DgEM.T.R
  60 DGIPYL.AD.TNM...NL..VKPS.E.K....LFL.PLYSVGDINNsQ.KS..YKL.SsSM.K.M
  61 ------.--.---...--..----.-.-....---.----------.-.--..---.-.--.-.-
  62 ------.--.---...--..----.-.-....---.----------.-.--..---.-.--.-.-
  63 ------.--.---...--..----.-.-....---.----------.-.--..---.-.--.-.-
  64 ------.--.---...--..----.-.-....---.----------.-.--..---.-.--.-.-
  65 DGNYYQ.IK.TDG...IA..YPVS.G.E....MTT.PFATVTYFEA.D.EN..LRL.EePV.N.L
  66 ------.--.---...--..----.-.-....---.----------.-.--..---.-.--.-.-
  67 DGNYYQ.VK.SDG...IT..YPVS.E.N....MTT.PFATVTYFET.D.EI..HRF.EkPM.N.L


             100         110       120        130       140         150
              |           |         |          |         |           |
   1 DD.VF.AQIKNEML.S.ENLFSAVKIYGTFKHMHVRMMP.AQQPPYTRLIDSARR.QPEE.KRQD
   2 EE.VE.ALLHELMP.S.KNLFYGIRMDGMFREVRTRTVP.KQEKPYTPLVEVTKS.QPIF.SFEN
   3 EE.VE.ALLHELMP.S.KNLFYAIRMDGTFREVRTRTVP.RQEKPYTPLVEVTKS.QPIF.SFEN
   4 EE.VE.ALLHELMP.S.KNLFYAIRMDGTFREVRTRTVP.RQEKPYTPLVEVTKS.QPIF.SFEN
   5 EE.VE.ALLHELMP.S.KNLFYGIRMDGTFREVRTRTVP.RQEKPYTPLVEVTKS.QPIF.SFEN
   6 EE.VE.ALLHELMP.S.KNLFYGIRMDGTFREVRTRTVP.RQEKPYTPLVEVTKS.QPIF.SFEN
   7 DD.VF.AQIKNEML.S.ENLFSAVKIYGTFKHMHVRMMP.AQQPPYTRLIDSARR.QPEE.KRQN
   8 DD.VF.AQIKNEML.S.ENLFSAVKIYGTFKHMHVRMMP.AQQPPYTRLIDSARR.QPEE.KRQN
   9 EA.VF.AEIKEKML.S.ENLFSAVKISGLFKKMHVRMMP.AQEPPYTRLIDSARR.QPEQ.TETY
  10 EA.VF.AEIKEKML.S.ENLFSAVKISGLFKKMHVRMMP.AQEPPYTRLIDSARR.QPEQ.TETY
  11 EA.VF.AEIKEKML.S.ENLFSAVKISGLFKKMHVRMMP.AQEPPYTRLIDSARR.QPEQ.TETY
  12 DD.VF.AQIKNEML.S.ENLFSAVKIYGTFKHMHVRMMP.AQQPPYTRLIDSARR.QPEE.KRQD
  13 EA.VF.AEIKEKML.S.ENLFSAVKISGLFKKMHVRMMP.AQEPPYTRLIDSARR.QPEQ.TETY
  14 EE.VF.DEVKKQMK.S.ENMFSAVKISGTFKKMHVRMMP.GQEPPYTRLIDSARR.QPEE.TREN
  15 KE.LE.DRIESYFD.G.QNLFRSIKITGKFPKMHVRMIP.RA-KSGTKFVEVSQN.QPEY.TEEN
  16 KE.LE.DRIESYFD.G.QNLFRSIKITGEFPKMHVRMIP.RA-KSGTRFVEVSQN.QPEY.TEEN
  17 QQ.IH.DVIDQQIP.S.DNLFCALRIDGNFRHAHTRTVP.RQTPPYRAMTDVLDD.QPVF.RFNQ
  18 KE.LQ.ERIESYYD.G.ENLFRSIKIHGTFAKMHVRMIP.RST-PDEKFAEVATH.QPEY.RAEN
  19 QQ.LH.DVIDQQIP.S.DNLFCALHIDGHFRHAHTRTVP.RQTPPYRAMTDVLDD.QPVF.RFNQ
  20 QT.VE.EKIAELVQ.G.PNVFYAVKMTGNFRYVDTRVVP.KQQRPYPPLIEAVKE.QPTY.HFEY
  21 QA.VE.EKIAELVQ.G.PNVFYAVKMTGNFRYVDTRVVP.KQQRPYPPLIEAVKE.QPTY.HFEY
  22 QA.VE.EKIAELVQ.G.PNVFYAVKMTGNFRYVDTRVVP.KQQRPYPPLIEAVKE.QPTY.HFEY
  23 KE.LE.DRIESYYD.G.VNLFRSIKIKGHFKHMHVRMIP.KSNA-DIKFADVATR.QPEY.EVDD
  24 KE.LK.ERIESYYD.G.ENLFRSIKIRGEFSHMHVRMIP.KST-PDTKFADVATH.QPEY.SRDN
  25 KE.LK.ERIESYYD.G.ENLFRSIKIRGEFLHMHVRMIP.KST-PDTKFADVATH.QPEY.SRDN
  26 QQ.IH.DVIDQQIP.S.DNLFC-VRIDGNFRHAHTRTVP.RQTPPYRAMTDVLDD.QPVF.RFNQ
  27 EQ.LK.KDILVREA.G.ENLFLAVKITGLFKNMHIRIMP.KQEKPYRRLAKISES.QPEF.QQSN
  28 ED.FE.KEINSMLP.S.RNLFYAIRIDGLFKKVQTRTVE.LQEKPYVPMVEAVKT.QPIF.NFDN
  29 KD.LE.EMILKNFE.G.QNLFKSLKIKGTFSRMHVRMIP.K-SPQHKRFADIASN.QPEF.TREN
  30 KD.LE.EMILKNFE.G.QNLFKSLKIKGTFSRMHVRMIP.K-SPQHKRFADIASN.QPEF.TREN
  31 SE.LE.DFLDLNLP.S.ENLFYAVKVDGNFSYVKARSVP.RQEKPYLQLADAVSS.QSVF.EFEN
  32 EE.VH.RQIDEIVG.T.DNLFCALRIDGRFRCVETRTVP.RQCRPYKPMQEAIEG.QPTF.HFEH
  33 EQ.VH.QLIDRLVP.S.DNLFCAIRIDGTFPSVQTRTVP.KQQRPYRPMLEVVKQ.QPVF.RFQQ
  34 SE.FE.SYFESKFP.S.KNMVYAVKLTGNFSKMKTRSVP.SQEKPYEKLVDVVKN.QSVF.EFEN
  35 QA.VE.EKIAELVQ.G.PNVFYAVKMTGNFRYVDTRVVP.KQQRPYPPLIEAVKE.RPTY.HFEY
  36 EA.LK.ETLDGFID.S.KNIFYAFYIKGSFNYVKTRTVV.KQSMPYKPMAEVVKN.QPVF.NYEN
  37 QQ.LG.HQLSKFFL.N.KNIPYAIRIDGTFKTLRLRSLR.KQQKPYPTLVQASEK.QAIF.NLNN
  38 EN.IK.AQILEKI-.S.PNFFAAIKISGLFAKMHVRVAP.KQEKPYPPFVEAARN.QPEF.TAEN
  39 KE.LE.DKILVDYP.Y.KNVFFAVKIVGTFSTVKTRVVE.KQTRPYKTLLQVADE.QAVF.ESTD
  40 TD.FE.QQVVHDYR.L.TNVFAAIRVDGTFAKVKTRVAP.RQEPPYKTLVAATAT.QPEF.TGEH
  41 KD.VD.ATLAKELS.Y.QNTFVAIKISGTFRTVQTRVVK.QQERPYPTLSETASK.QQVF.NAED
  42 KQ.LQ.QSLDRRLP.T.KNYPYAIRIQGNFPYVKFRIPP.KQTPPYRSLAEALKG.QSIF.ELRN
  43 KEgFE.AIVDHLVN.N.PNLFAAVRFTGMFERVETRTVF.CQCQPYPPMLEVVAR.QPTM.QLGA
  44 NQ.LT.KMLEEKFE.N.KNVFYAVKLTGTFKMVKARTVP.KQTRPYPQLTEVTKK.QSEF.EFKN
  45 AD.FE.HWLSEQLG.T.INSFYAVRIEGRFSEVKTRTVA.RQEKPFRPITEAVAT.QSAR.TFEH
  46 DS.FQ.KRVEEEYK.L.KNVFAAIRVHGEFTNVLARSAD.KQEKPYPPFSKVAAA.QHEF.HADS
  47 DS.FQ.KKVEEEYK.L.KNVFAAIRVHGEFTNVLARSAD.KQEKPYPPFSKVAAG.QHEF.HADS
  48 SE.LS.DFITSLLP.S.ENYMYAVRISGMFSSVSVRTVT.KQERPYRPMTQATGD.DAEL.EFTN
  49 SN.LT.QNLKDEQL.F.-NVFSALKLHGEFAHVHVRIVT.KQEKPYPSLLQVAEQ.QPEF.KADN
  50 QQ.IH.DVIDQQIP.S.DNLFCALRIDGNFRHAHTRTVP.RQTPPYRAMTDVLDD.HRCS.ALTS
  51 KD.LL.ALLLKLFPqS.KNHFLAIRMDGTFKRIKVRTAG.GQCFPREGMLAVAGR.QATN.TFEA
  52 QQ.LG.HQLSKFFL.N.KNIPYAIRIDGTFKTLRLRSLR.KQQKPYPTLVQASEK.QAIF.NLNN
  53 FD.SL.NNISKQHQ.SwANLPASIQINASFSKLKVRVAP.KQMKPYPPFVDVTLK.QPVF.NYEN
  54 PD.LY.ATLDTLYP.T.LNVMYAFRIDGAFSYMQTESTP.GQSKPYIPFLELLAQ.ATQF.YNYD
  55 KD.LLaKVLSDLLP.GtKNHYVAFRVEGTFKSVTVRTVG.GQQSPGESLAELGKR.QASH.TFSD
  56 ED.FK.ATLDKKLP.T.VNVFYAIKVVGVFDSVQYQNFP.RMEKPYASFSEGLAN.AVNE.EVND
  57 ED.FL.SALTKRFP.T.VNTAYTIVMTGQFKEVTVSSKPaNNTRPYD---EIMAD.QPYF.TKEN
  58 QS.LE.NKLLKIFD.T.KNLIQAVYAKAIVKQLHSRTFI.RQEKPYVEIQKIKEL.QSEI.WIQN
  59 EE.FX.QEIASLLP.S.KNLFYAIRLDGVFKKVQTRTVE.RQEKPYVPMIEAVKT.QPVF.NFDD
  60 KD.FL.LFLENQLN.L.KNYPALLNIEVSLESALLRSIK.KQEEPFLNFIDSLKK.YEVRkELKN
  61 --.--.------MP.S.ENLFYAVRVDGNFSYIKARSVP.RQEKPYPKLADAVSS.QSVF.EFEN
  62 --.--.--------.-.---MYAIRIDGNFSSMKVRSVP.AQERPYPLLVDVVANeQAVF.EHED
  63 --.--.--------.-.----------------------.---TSDRKFAEVAVN.QPEY.SKEN
  64 --.--.--------.-.----MLFKIKGNFSYLKVQSVP.KQELPYRKLANGVAN.QTVF.EFEN
  65 TE.LE.AFLD-LNP.-.----------------------.---------------.----.----
  66 --.--.--------.-.----------------------.---------------.----.----
  67 TE.LE.QYLYLNLP.P.ENFVYAV---------------.---------------.----.----


              160        170       180       190        200       210  
               |          |         |         |          |         |  
   1 IRGAIVGF.FTPE.LFHGVGSAGFHIHFADDERAYGGHVLDFEVD.DVVVEIQNFETFQQHFPVN
   2 TEGTLAGF.WTPD.YAQGIGVAGFHLHYIDDERSGGGHVFDYVVE.NCTIQICQKAHMHLALP-E
   3 TEGTLAGF.WTPD.YAQGIGVAGFHLHYIDDERSGGGHVFDYVVE.NCTIQICQKAHMHLALP-E
   4 TEGTLAGF.WTPD.YAQGIGVAGFHLHYIDDERSGGGHVFDYVVE.NCTIQICQKAHMHLALP-E
   5 TEGTLAGF.WTPD.YAQGIGVAGFHLHYIDDERSGGGHVFDYVVE.NCTIQICQKAHMHLALP-E
   6 TEGTLAGF.WTPD.YAQGIGVAGFHLHYIDDERSGGGHVFDYVIE.NCTIQICQKAHMHLALP-E
   7 IRGAIVGF.FTPE.LFHGVGSAGFHIHFVDDERAYGGHVLDFEVD.DVVVEIQNFETFQQHFPVN
   8 IRGAIVGF.FTPE.LFHGVGSAGFHIHFADDERAYGGHVLDFEVD.DVVVEIQNFETFQQHFPVN
   9 VKGSVVGF.FTPE.LFHGIGSAGFHVHFANDDRNFGGHVLDFEVE.DVKVEIQNIETFEQHFPIQ
  10 VKGAVVGF.FTPE.LFHGIGSAGFHVHFANDDRNFGGHVLDFEVE.DVKVEIQNIETFEQHFPIQ
  11 VKGSVVGF.FTPE.LFHGIGSAGFHVHFANDDRNFGGHVLDFEVE.DVKVEIQNIETFEQHFPIQ
  12 IRGAIVGF.FTPE.LFHGVGSAGFHIHFADDERAYGGHVLDFEVD.DVVVEIQNFETFQQHFPVN
  13 VKGSVVGF.FTPE.LFHGIGSAGFHVHFANDDRNFGGHVLDFEVE.DVKVEIQNIETFEQHFPSQ
  14 IKGSIVGF.FTPE.LFHGIGSAGFHIHFANDDRDFGGHILDFEVD.DVTVEIQNFETFEQHFPVD
  15 IKGTIVGI.WTPE.MFHGVSVAGYHLHFISEDFTFGGHVLDFIID.NGTVEIGAIDQLNQSFPVQ
  16 VKGTIVGI.WTPE.MFHGVSVAGYHLHFISEDFTFGGHVLDFIID.NGTVEIGAIDQLNQSFPVQ
  17 REGVLVGF.RTPQ.HMQGINVAGYHEHFITDDRQGGGHLLDYQLE.SGVLTFGEIHKLMIDLPAD
  18 ITGTIVGI.WTPE.IFHGVSVAGYHLHFISDDHTFGGHVMDYVIS.EGQVEVGAVDQLDQRFPVQ
  19 RKGTLVGF.RTPQ.HMQGLNVAGYHEHFITDDRQGGGHLLDYQLD.SGVLTFGEIHKLMIDLPAD
  20 ITGTIVGF.WTPA.YISGIGVSGYHVHFIDDMRKIGGHVFDYEML.EGTVEVAQQTEFELQLP-Q
  21 ITGTIVGF.WTPA.YISGIGVSGYHVHFIDDMRKIGGHVFDYEML.EGTVEVAQQTEFELQLP-Q
  22 ITGTIVGF.WTPA.YISGIGVSGYHVHFIDDMRKIGGHVFDYEML.EGTVEVAQQTEFELQLP-Q
  23 ISGTIVGI.WTPE.MFHGVSVAGYHLHFISDDLTFGGHVMDFVIE.NGIIEVGPVDQLDQRFPVQ
  24 VAGTIVGF.WTPE.IFHGVSVAGYHLHFISDDLTFGGHVMDFVIK.EGIIEVGAVDQLDQRFPVQ
  25 VAGTIVGF.WTPE.IFHGVSVAGYHLHFISDDLTFGGHVMDFVIK.EGIIEVGAVDQLDQRFPVQ
  26 REGVLVGF.RTPQ.HMQGINVAGYHEHFITDDRQGGGHLLDYQLE.SGVLTFGEIHKLMIDLPAD
  27 VQGTLVGF.FTPE.LFQGVAAAGFHLHFIDDTHTFGGHVMDFEVA.EGKVEISRISSLVQHFPVD
  28 VRGTIVGF.LTPA.YANGIAVSGYHLHFIDEGRNSGGHVFDYVLE.DCTVTISQKMNMNLRLP-N
  29 VSGTLVGI.WTPE.LFHGVGVKGFHVHFISDDLTFGGHVMDYSLT.QGKVEIGKVDQLDQCFPTQ
  30 VSGTLVGI.WTPE.LFHGVGVKGFHVHFISDDLTFGGHVMDYSLT.QGKVEIGKVDQLDQCFPTQ
  31 VSGTLVGF.RTPE.YVKGVNVPGYHLHFITENRSAGGHVLDLEME.KGDAALDITSIFLMELP-A
  32 RSGSVIGF.RSPA.YTQGINVAGYHEHFITDDRQGGGHILNYDVE.NGTLTFGVIAKLIIDLP-Q
  33 QHGVIAGF.RSPQ.YTTGINVPGYHEHFITQQRTGGGHIQDYIIR.SGFLQIGRVSRLVVDTPV-
  34 VSGTVVGF.WVPE.FMSGLNVPLYHLHFITDDRLAGGHILDFEID.SVEASFDTTPEFYMVLP-T
  35 ITGTIVGF.WTPA.YISGIGVSGYHVHFIDDMRKIGGHVFDYEML.EGTVEVAQQTEFELQLP-Q
  36 VKGHIVGF.RCPD.YVEGLNVPGYHFHFLSDDKKFGGHVSDISVK.NAEVFIQNCLCFRMELP-Q
  37 VKGTVVGF.WFPS.YWGGIAVAGFHLHFVTADRTTGGHVLEIALN.QGKVSLAPVHQLDIYLP-E
  38 IQGTVVGF.FTPK.LFHGASAAGFHLHFISEDHQFGGHILDFGIK.QGTVSWMETAELRQHFPVH
  39 VSGTVIGY.FAPK.MFQGMAAAGYHLHFLADNKSIGGHLLDFKIK.EATVYLQPFTTIEQHLPMD
  40 VDGTIIGY.YAPH.LFQGATVGGFHLHFLSKDHQLGGHLLGFEVE.QATLKVQHFADFHVHLPID
  41 VRGTVVGY.YTPD.LFHGAGVAGMHLHFIDDQHEFGGHLLDFKAD.QVKLSWQLLDGLDLNLPIQ
  42 INGTLVGF.RTPE.YMQGVNVNGYHFHFIAANHTTGGHILDGQFQ.NAKIEIDPLLNVEINLP-K
  43 STGTMLGF.RTPG.YMQGVNVAGYHLHFLTEDGRRGGHVTDYGVL.RGRLEVGVISDVEIQLP-R
  44 VKGTLIGF.YTPN.YAAALNVPGFHLHFITEDKTSGGHVLNLQFD.NANLEISPIHEFDVQLP-H
  45 IDGTLAGY.FTPR.FGHGIAVAGYHLHFIDQERSGGGHVFDYTVQ.DVTVTFEEKPKLDLRLP-T
  46 LTATMVGY.YSAA.MYEGTTAAGFHLHILSDDRQFGGHLLDFKIK.KADLQVQIFQDFQLHLPIE
  47 LTATMVGVlFSSD.VWKGPTAAGFHLHILSDDRQFGGHLLDFKIK.KADLQVQIFQDFQLHLPIE
  48 VSGVVAGF.RTPI.YEKGIGVPGCHVHFIDTDRTSGGHVLDFTMS.EGTIEVCPGTDLQLRLPL-
  49 ITGTLVGY.YAPK.VFGGPTAAGWHLHFLSDDLTFAGHVLDFEAT.DVDGTLEVFDNFLQHLPIN
  50 VKGCWLGS.ARRS.ICRASTWPAITKHFITDDRQGGGHLLDYQLE.SGVLTFGEIHKLMIDLPAD
  51 VKGTIIGF.RCPA.YVMGLNVAGDHLHFIDEERQKGGHILEFETEgDVEVGVSLMSKFHLEVPTE
  52 VKGTVVGF.WFPS.YWGGIAVAGFHLHFVTADRTTGGHVLEIALN.QGKVSLAPVHQLDIYLPKQ
  53 VSGTLIGD.FGPD.LYSGIMASGWHLHFLSDDRTIGGHVLDFKAS.DVLGRIDLFNELNIALPTD
  54 VKGTVVGF.RFPA.YMEQVNVGGYHMHFLSDDKKVGGHIKDCTMN.RGRVAIDVTHKADVIVP-R
  55 IKGTIIGF.RSPT.FMQGISVAGDHLHFLSADKKAGGHVLAVQGDgELKVTAAPITAVNLQLPSE
  56 VEGTFMGF.RFPEkTAPDLNVPQYHLHLLTNDKQNAGHINTCKIR.RARVYIDAASQLKVDLP-N
  57 ISGTMVGV.WAPK.HLTDLFGLGFHLHFVSDDKTFTAHVQNFITE.NLEIEIGKITKIDQEFPDD
  58 KEIELVGF.YTPS.LFSNFNIEGFHWHYISQDKDYGGHVIDMELE.SISLIIKPIHDLNYHSPVC
  59 IQGTIAGF.WTPG.YANGIAVSGYHLHFIDEGRNSGGHVFDYVIK.DCKVTISQKMNMNLKLP-N
  60 LEGSLIGV.WYPK.HLQPINNSGFHFHFIDKTNKIGGHLLDFEIKpNIKIAFEEKTNLVVEF-SE
  61 ISGTLVGF.RTPE.YVKGVNVPGYHLHFITEDRSAGGHVLDIEME.NGESSLDITNAFFMELP-T
  62 VEGSIVGF.WLPY.YVESMNVPGYHFHFIDSERTEGGHVLDYTLI.DGTVSIDRTTGFELLLP-G
  63 VTGTIVGI.WTPE.IFHGVSLAGYHLHFVSDDLSFGGHVMDFVIK.EGIVELGAIDQLDQRFPVQ
  64 VSCTLVGF.RTSD.YVTGINVPGYHLHFINEKRSTDEHVLEFELE.NGTTALDSTPSFFMEFP-K
  65 --------.----.-------------------------------.-------------------
  66 --GTIVGI.WTPE.IFHGVSVAGYHLHFISDDLTFGGHVMDYVIS.EGMVEVGPVDQLDQRFPVQ
  67 --------.----.-------------------------------.-------------------


              220        230        
               |          |        
   1 N...ETFVKAKI.DYKDVAEEIREAE....
   2 T...ADFMAAEL.SRENLEDNIATAEgae.
   3 T...ADFMAAEL.SRENLEDNIATAEgae.
   4 T...ADFMAAEL.SRENLEDNIATAEgae.
   5 T...ADFMAAEL.SRENLEDNIATAEgae.
   6 T...ADFMAAAL.SRENLEDNIATAEgae.
   7 N...ETFVKAKI.DYKDVAEEIREAE....
   8 N...ETFVKAKI.DYKDVAEEIREAE....
   9 D...EDFINANI.DYKDIADEIREAE....
  10 D...EDFINANI.DYKDIADEIREAE....
  11 D...KDFTKANI.DYKDIADEIREAE....
  12 N...ETFVKAKI.DYKDVAEEIREAE....
  13 D...KDFINANI.DYKDIADEIREAE....
  14 A...KSFTDADI.DYKDIADEIREAE....
  15 D...RKFLFADL.DIEALKKDIDVAE....
  16 D...RKFLFADL.DIEALKKDIDVAE....
  17 S...A-FLQANL.HPSNLDAAIRSVEn...
  18 D...RQYLFAKF.NAKDIRGDIDKAE....
  19 S...A-FLQADL.HPDNLDAAIRAVEn...
  20 T...TEFLRSDL.STPDMLEQIEAAEn...
  21 T...TEFLRSDL.STPDMLEQIEAAEn...
  22 T...TEFLRSDL.STPDMLEQIEAAEn...
  23 D...RQYLFAKF.NVDEMRKDITKAE....
  24 D...RQYLFAKF.NVDEMKKDIEKAE....
  25 D...RQYLFAKF.NVDEMKKDIEKAE....
  26 S...A-FLQANL.HPSNLDAAIRAVEn...
  27 D...PTFVHETI.DYADLAAEIQQAE....
  28 T...ADFFNANL.DNPDFAKDIETTEgsp.
  29 D...QEFLKANF.DLQKLREDIDLSE....
  30 D...QEFLEANF.DLQKLREDIDLSE....
  31 S...GDFYNAEL.G-QNLQEDLEKVEk...
  32 D...REFLNADL.SSENLNSVIKSVEs...
  33 S...RDFLEANL.TPNNIRTAIEAAEk...
  34 S...GEFYSMEF.S-DNLENDLKAVEkq..
  35 T...TEFLRSDL.STPDMLEQIEAAEn...
  36 S...ESFYSMK-.-VENRNDEISKVEk...
  37 T...KSFAHANL.SSEELHSAIKKAEggs.
  38 D...ADYRNKEI.DIAKALSAIEEAE....
  39 N...QEFLNKDL.DIADMHDQIQKAEg...
  40 N...EAYLQEQF.DNEAIDHAINKAEr...
  41 D...AEFMAHEAsDAEKIQQSISESE....
  42 T...AEFVQADL.E-DGKPAEVNRFEpk..
  43 T...EQFARANL.SPENIHEAIRVAEgg..
  44 T...DDFAHSDL.-TQVTTSQVHQAEser.
  45 T...AAYRTADL.ESHDIEKEIQIAEg...
  46 N...PDFRRREL.DLETLKKAIEKTE....
  47 N...PDFRPTQL.DLETLKKAIEKTE....
  48 T...QDFSKASL.APDDLDAQIHATEvkg.
  49 N...ADFRSMNQ.DIAGLDKAIEASEggk.
  50 S...A-FLQANL.HPSNLMQRSVPSKtnr.
  51 D...EEFNEASL.-VHD-KDGIEKVEg...
  52 NpssRQFIFGGI.AFGN---------....
  53 N...PDFNNHEA.DILNIREAIDVAEr...
  54 D...KDFYESPL.DGP----------....
  55 D...DAFNQAKL.ARDD--EGIAAVEg...
  56 T...LPYYQSPL.DGEVIGSG-----....
  57 D...ENFDQHLF.Q------------....
  58 -...LEFLELDL.SENK---------....
  59 T...ADFFNANL.DNPNFAKDIETTEgsp.
  60 N...EDLKNLTI.-I-----------....
  61 S...GDFYNVEL.G-QDLQADMEKVEk...
  62 D...DDFLSADL.-LRDKGEELSVVEkdd.
  63 D...RDYLFAKF.NMDEMKEDIDRVE....
  64 S...YSFTKVEL.G-QDLKIEMETVEk...
  65 -...--------.-------------....
  66 D...RQYLYAKF.NAKEVREDIDKAE....
  67 -...--------.-------------....