Citations (SAM, SAM-T99, HMMs)
10 20 30 40 50
| | | | |
1 SEESRESPAEHGYYMPAEWDSHAQTWIGW.....PE...RQDNWRH....NAL.PAQRV.FADVA
2 ----RESPAEHGYYMPAEWDSHAQTWIGW.....PE...RQDNWRH....NAL.PAQRV.FADVA
3 ----RESPAEHGYYMPAEWDSHAQTWIGW.....PE...RQDNWRH....NAL.PAQRV.FAGVA
4 -----STPRADGFRMPAEWEPHEQTWMVW.....PE...RPDNWRN....GGK.PAQAA.FAAVA
5 -------PAEHGYYMPAEWDSHAQTWIGW.....PE...RQDNWRH....NAL.PAQRV.FADVA
6 --TIDSSSKKDGFRMPGEFEKHAGCYIIW.....PE...RPDNWRL....GAK.PAQKA.FVDVA
7 --TIDSSSKKDGFRMPGEFEKHAGCYIIW.....PE...RPDNWRL....GAK.PAQKA.FVDVA
8 --TIDSSSKKDGFRMPGEFEKHAGCYIIW.....PE...RPDNWRL....GAK.PAQKA.FVDVA
9 --TLNSTPRADGFHMPAEWAPQTQVWMVW.....PE...RPDNWRL....GGK.PAQAA.HVAIA
10 --TLKSTPRADGFYMPAEWAPQTQTWMIW.....PE...RPDNWRL....GGK.PAQAA.HAAVA
11 --TLQTSPKKDGYRMPGEFEAHKDVYLLW.....PE...RPDNWRE....GAK.PAQAT.FAKVA
12 --TLNSTPRADGFHMPAEWAPQTQVWMVW.....PE...RPDNWRL....GGK.PAQAA.HVTLA
13 --TLSGTPRADGFRMPAEWEPHAQTWMLW.....PE...RPDNWRL....GGK.PAQAA.FATVA
14 ---MNSTPKKDGFWMPGEWEKHDQCWMIW.....PE...RSDNWRL....GAK.PAQRV.FVNVA
15 --TLNSTPRADGFHMPAEWAPQTQVWMVW.....PE...RPDNWRL....GGK.PAQAA.HVAIA
16 ---LKGLPVEDGFRMPGEYEPHIGCFMIW.....PE...RPDNWRL....GGK.PAQQN.YKEVA
17 ---LKGLPVEDGFRMPGEYEPHIGCFMIW.....PE...RPDNWRL....GGK.PAQQN.YKEVA
18 ---LKGLPVEDGFRMPGEYEPHIGCFMIW.....PE...RPDNWRL....GGK.PAQQN.YKEVA
19 ----NTTPKQDGFRMPGEFEKQKQIWMLW.....PW...RNDNWRL....GAK.PAQKA.FLEVA
20 ---LKGLPVEDGFRMPGEYEPHIGCFMIW.....PE...RPDNWRL....GGK.PAQQN.YKEVA
21 ---IGTTPKEDGFRMPGEFEAQDQIFMIW.....PE...RPDNWRD....GAK.PVQIA.FTNVA
22 ----PGTPRQDGFFMPAEWAPQDAVWMLW.....PY...RQDNWRG....KAI.PAQQT.FAKVA
23 ----PGTPRQDGFFMPAEWAPQDAVWMLW.....PY...RQDNWRG....KAI.PAQQT.FAKVA
24 -----TTPAQDGFYFPAEFQPVSEVWLAW.....PE...RKDNWRD....DAL.PAQET.FARIA
25 --------------MPAEWAAQQAVWMIW.....PY...RPDNWRA....AGA.YAQAT.FAKVV
26 -------PKKLGYHMPAEYEPHHGTLMIW.....PI...RPGSWPF....QGK.AAKRA.FTQII
27 -------PKKLGYHMPAEYEPHHGTLMIW.....PT...RPGSWPF....QGK.AAKRA.FTQII
28 ---MEGRPAKMGFRMPAEWEPHEQCWMGW.....PE...RRDNWRE....LAG.PARKV.FARTA
29 ---LDTTPKQDGFRLPGEFEAKAGCWLGW.....PE...RTDVWRN....GAK.PAQKV.WVQIV
30 --------------------------MIW.....PE...RPDNWRD....GGK.PVQEA.FTNVA
31 -------PAELGYRMPAEWEPHQATWLSW.....PH...KEESWPG....IID.RIWPV.YARFV
32 ------------YFMPPEWAPHASTWLSW.....PH...KLESWPG....KFE.PVPAV.FAELA
33 --TLHSTPRADGFHMPAEWAPQTQTWMIW.....PE...RPDNWRL....GGK.PAQAA.HVAVA
34 -------------RLPAEWEEQDGVLIAW.....PH...PGSDWYP....WLR.LVEPV.FAQIV
35 --------------LPAEWEEQDGVLLAW.....PH...AESDWLP....WLP.MVELV.FAQIV
36 -------PKQTGFYMPGEFEQHKRTWMIF.....PF...RNDNWRQ....EAV.PAQKT.ITNLA
37 ------TPAQQGYSFPAEWAKHKATWLSW.....PH...KEASWPG....KLD.SIFPQ.YAQFI
38 ---QDPTPRDLGFAMPPEWAPHEATWMGY.....PA...DDELWFG....HLA.GVRDE.YAGLV
39 -----------DRRFPAEWEAQDGVLIAW.....PH...ADSDWRS....LLD.QVDRV.YRDLA
40 -------------RMPAEWERQSAVLMAM.....PH...EESDWYP....YLE.EAREN.FIQII
41 --------AADHWHMPDEHLPQERVFLAY.....AA...SPSIWKD....LAE.DVNRS.VALLA
42 -----------TWHMPDEGAPHTATWMAF.....GP...SEDIWGA....RLL.PVARAnLAAIA
43 ----ETPLTTFPFRFPAEWEPQSAILIAW.....PH...ANTDWSA....HLA.DVEET.YIALV
44 --------AADHWHMPDEHLPQERVFLAY.....AA...SPSIWKD....LAE.DVNRS.VALLA
45 --------------MPDEGAPHAATWMAF.....GP...SLSVWGAr...LLP.EVRRD.LARVA
46 ----ETPLTTFPFRFPAEWEPQSAILIAW.....PH...ANTDWSA....HLA.DVEET.YIALV
47 -----TPLTTFPFRFPAEWEPQSAILIAW.....PH...ANTDWSA....HLA.DVEET.YITLV
48 ------------FRMPPEWAPHERTWMAW.....PG...PNATFTDae..ELA.GARAA.WASVA
49 ----ETPLTTFPFRFPAEWEPQSAILIAW.....PH...ANTDWSA....HLA.DVEET.YIALV
50 -------PAADGFRMPAEWTPHERTWMAW.....PG...PNPTFDHpd..DLA.ESCRA.WADVA
51 ------------FFRPAEWLPHRACWLAF.....PS...HEDLWGE....LLP.QVRFE.FAALC
52 -------PLSDGFIQPAEWQPHSACWLAW.....PS...DAELWQS....DLP.KAQVE.FAGLC
53 -----------RWFMPDEGDKHERAYMAF.....GA...QDAIWED....FTE.DVQEA.LGRIA
54 ------------LRFPAEWEPQSAVLVAW.....PH...AGTDWAE....RLA.DVEET.YIALV
55 -------------HLPAEWHLQSGIQLTW.....PH...AGTDWAY....MLK.EVQEC.FVNIA
56 --------------MLAEFEKIQAILMAF.....PH...EFSDWAY....CIK.EARES.FLNII
57 --------------MLAEFEKIQAILMAF.....PH...EFGDWAY....CIE.EARES.FLHII
58 -------KTFGKYTMPDEKDKHEGTWLQW.....PH...EYTYGEE....YKQ.EVEPI.WVKIA
59 ----------DSVRFPAEWESQSAILIAW.....PH...AGTDWAE....RLA.EVEDT.YIALV
60 -------KTVGKYTMPDEKDKHEGTWLQW.....PH...EYTYGEE....YKQ.EVEPI.WVKMA
61 -----------KYRLKAEWEEQIAILMAF.....PH...KNSDWAI....HIE.VAREC.FVRII
62 --------------MPDEKDKHEGTWLQW.....PH...EYTYGEE....YKK.EVEPI.WVKMA
63 ------------VTVPAEWAPHRAMWVGF.....PS...HAELWQE....DLE.QAQQE.VADLA
64 ---------NSGWMMPAEWVTHAATWMVW.....PH...NQALWESgwgvTLP.LVQED.FARVA
65 -------------RMPAEWEPHQRTWMAF.....PT...PNPTFGEaggpDLT.RARAA.WSTVA
66 ---------------LPEWAPQEAVQLTW.....PH...DRTDWAY....MLD.EVETC.FVRIA
67 ------------FYMPAEWEKHEGTWLQW.....PH...DRTHRGE....GYRaKLDDI.WVTMV
68 ------------YHQPAEWMPHDAVWIGF.....PS...DASLWLE....DLE.PAQAE.VVAFA
69 ----------RSYRFPAEWEPCEAVWLAW.....PH...NRDTWPG....HFE.PVPAA.FAQFV
70 -----------------------------.....--...---EWGV....SLA.DVQQD.FAAVA
71 -----------------------ATWLGW.....PVlhdREDLWGS....HYA.QVCRE.FALVA
72 ----------------PEWSEQEYLMLSL.....PH...EKSDWNP....YLE.EILQS.YKEFV
73 ------PHMTSQFRMPPEWHPQDWLWIGF.....PH...LAEEWSG....VID.EAQVQ.IAAFA
74 --------QAKTFRMPAEFEPITSIWMAY.....PT...YENQAGY....PSQ.TVQKA.---MV
75 ----------------PEWSAVRAIVIAW.....PY...EDSDWQD....NYA.QAEQC.YWAML
76 -----------------------------.....--...-------....---.-----.-----
77 --------RPVTYRLPAEDAPHASTYMAFas9wlPV...TPQSTDA....GID.RVRAD.LMDVA
78 ---QETNPPAGPVRAIAEYERSAAVLVRY.....PF...G------....---.----I.PMELI
79 ---QETNPPAGPVRAIAEYERSAAVLVRY.....PF...G------....---.----I.PMELI
80 -----------------------------.....--...-------....---.-----.-----
81 -----------------------------.....--...-------....---.-----.-----
82 -----------------------------.....--...-------....---.-----.-----
83 ---LEGKPSLMGYRMPAEWEPHQQCWMGW.....PE...RPDNWRE....NAR.FGQHA.FVEVA
84 -----------------------------.....--...-------....---.-----.-----
85 -----------------------------.....--...-------....---.-----.-----
60 70 80 90 100
| | | | |
1 KAIS.....K.FEPVTVCASPAQWENAR.....KQLP..EDIRVVEMSMNDSWFRDSGPTF...I
2 KAIS.....K.FEPVTVCASPAQWENAR.....KQLP..EDIRVVEMSMNDSWFRDSGPTF...I
3 KAIS.....K.FEPVTVCASPAQWENAR.....KQLP..EDIRVVEMSMNDSWFRDSGPTF...I
4 KAIA.....R.FEPVTVCASAGQYENARa....RLDD..GNIRVVEISSDDAWVRDTGPTF...V
5 KAIS.....K.FELVTVCASPAQWENAR.....KQLP..EDIRVVEMSMNDSWFRDSGPTF...I
6 TAIS.....R.FEPVTVVASSSQYVNAR.....YMLP..DEIRVVEMDNDDAWVRDSGPTF...V
7 TAIS.....H.FEPVTVVASSSQYVNAR.....YMLS..DEIRVVEMDNDDAWVRDSGPTF...V
8 TAIS.....H.FEPVTVVASSSQYVNAR.....YMLP..DEIRVVEMDNDDAWVRDSGPTF...V
9 KAIA.....R.FEPVTVAVSAAQYDNARa....RLDM..PNIRVVEMSSNDAWVRDSGPTF...V
10 KAIA.....R.FEPVTVAVSAGQYENARa....RLDV..PNIRVVEMSSDDAWVRDSGPTF...V
11 ETIA.....Q.FESVTVGVSDRQYTNAR.....HMLA..DNIQVVEMSNNDSWIRDCGPTF...V
12 KAIA.....R.FEPVTVAVSAGQYENARr....QLDQ..PNIRVVEISNDDAWVRDTGPTF...V
13 RAIA.....R.FEPVTVGVSAAQYENACv....RLAG..ADIRVVELSSDDAWVRDTGPTF...L
14 NAIA.....K.YEKVTMLVSHQQFENAR.....NLLD..QNVRVIEMSNDDSWMRDVGPTI...V
15 KAIA.....R.FEPVTVAVSAAQYDNARa....RLDM..PNIRVVEMSSNDAWVRDSGPTF...V
16 VAIS.....N.FEPVTMFVSPNQYKNAR.....KELP..DTIRVIEMSNDDAWIRDYGPSF...L
17 VAIS.....N.FEPVTMFVSPNQYKNAR.....KELP..DTIRVIEMSNDDAWIRDYGPSF...L
18 VAIS.....N.FEPVTMFVSPNQYKNAR.....KELP..DTIRVIEMSNDDAWIRDYGPSF...L
19 EAIS.....E.FEPVSLCVPPLQYENALarvs.ELGS..HNIRIIEMTNDDAWIRDCGPTF...L
20 VAIS.....N.FEPVTMFVSPNQYKNAR.....KELP..DTIRVIEMSNDDAWIRDYGPSF...L
21 KAIS.....R.FTPVTMLVSQSQYQNAR.....YQLP..ADVRVLEVSNNDSWVRDCGPSF...V
22 EAIS.....R.ATPVFMGVPAEFMAQAK.....ATMP..ANVTLVEMASDDAWMRDTGPTM...V
23 EAIS.....R.ATPVFMGVPAEFMAQAK.....ATMP..ANVTLVEMASDDAWMRDTGPTM...V
24 NLIA.....E.VTKVCVAVCSHNFDRAR.....QMLH..SDVRLVEIPFNDAWMRDIGPTV...L
25 DAIG.....A.ATPVYMGVPKAFLAKAK.....TVMP..SHVTLVEMDSNDCWARDTGPTV...V
26 ETIA.....E.GERVYLLVEQAYLSEAQ.....SYLG..DKVVYLDIPTNDAWARDTGPTI...L
27 ETIA.....E.GERVYLLVEQAYLSEAQ.....SYLG..DKVVYLDIPTNDAWARDTGPTI...L
28 IAIS.....K.FESVTICASAKQYPYVH.....ELMLhqPNIRVVEMSMNDCWFRDIGPTF...I
29 TAIS.....Q.SEPVTVCASASQFATAR.....RQLP..PQVRVVEMTCNDTWFRDSGPCF...V
30 KAIS.....Q.FTPMNVVVSQQQFQNCR.....RQLP..PEITVYEMSNNDAWVRDCGPSF...V
31 AELA.....R.GETVHINVNDAAMADQArf6aeAGAV..GDIRLHEFPTNDAWCRDHGAIF...V
32 YQLS.....R.SETVNINVLDDAMEAQAr10peGKYA..ERIVFHRIPTNDAWCRDHGPNY...V
33 KAIA.....R.FEPVTVAVSAGQYENARa....RLDV..PNIRLVEMSSDDAWVRDTGPTF...V
34 REIT.....R.FETALVVAADGERTAALleav.GARM..ERVAIVELPTNDTWARDFGPVT...V
35 KEIA.....H.FEAVLLVAAEGERTSAIlsaa.GASM..ERVRIVEIPTNDTWARDFGPLT...V
36 RKIS.....E.FEEVIMIVSRDHLNKAM.....DLLHd.SGVKMVTADSDDCWARDTGATF...I
37 KLIA.....E.GEEVRINVANAAMEAFArg7kaGADM..HNVFFHHFPTNDAWCRDHGPAF...L
38 RTIA.....R.FERVELLVRDEESERDAra...RLTG..HNVRFHRVPLDDSWLRDSGPLF...V
39 EAVT.....R.FEQLLIVTPEPDRVAEQlaqt.TANC..DRIQIVELPTNDTWSRDFGPLT...V
40 EEIT.....K.RERCLLLVDDWKLYEER.....LGHL..SNLIPLELLTNDTWARDFGPIG...I
41 RTIA.....R.YQPVTLLCRPTQEAAAR.....RACGg.ANIDYLALPLDDIWVRDYGGCF...V
42 KAIA.....A.HEPLKMLVREQDYAIAS.....RLCG..SSVELVQHPVDDLWMRDTGPVF...V
43 AAIT.....R.FQMVIICVLDDDLQTYTea7saSVAM..QQVRFTVASYNDTWLRDSGPIT...L
44 RTIA.....R.YQPVTLLCRPTQEAAAR.....RACGg.ANIDYLALPLDDIWVRDYGGCF...V
45 SAIA.....A.FEPVRMLARENELDLAG.....RLCG..SGVELVAQPLDDLWIRDSGPVF...V
46 AAIT.....R.FQMVIICVLDDDLQTYTea7saSVAM..QQVRFTVASYNDTWLRDSGPIT...L
47 AAIT.....R.FQMVIICVLDDDLQTYTea7saSVAM..QQVRFTVASYNDTWLRDSGPII...L
48 RAVR.....R.FEPVTMVHGPGQAATAR.....ELLG..PDVDLVERELDDAWMRDIGPTF...V
49 AAIT.....R.FQMVIICVLDDDLQTYTea7saSVAM..QQVRFTVASYNDTWLRDSGPIT...L
50 RAIR.....R.FEPVTVVCGPGRSAEAR.....DLLG..PGIDTVERDLDDAWMRDIGPTF...L
51 RAIA.....D.PDPVTGQCRGEQLKILVl11hsYLSD..LNPQFYQLTFGDIWLRDTAPVG...L
52 RTIAdp9lpR.GEYLKILVPDAEAERAA.....RLALegLGARFHRIRFGDIWLRDTAPIF...L
53 RAIA.....R.YEPLTIYCRSGERSLAE.....EICGs.SNITYQIANLDDIWMRDISANF...V
54 TAIS.....R.FEPVVICVADDDLQIYAea7saRVDM..TRVRFVIAAYNDTWLRDSGPIT...L
55 REIA.....K.RELLLIVTPEPEEVKKQiva..TVNM..DNVRFLRCETNDTWARDHGAIT...M
56 QTIA.....K.HAKVLVCVHTNDIIGYEt....LKNL..PGVEIARIDTNDTWARDFGAIS...V
57 QTIA.....K.HAKVLVCVHTNDTIGYEt....LKNL..PGVEIARIDTNDTWARDFGAIS...V
58 SALT.....E.GEKVHIVAYDEEEKERInk7dkGLNM..DKIDFFIAPTDDVWARDSGPIF...V
59 TAIT.....R.FQPVIICVADDDLQIYAea7saRVEM..AQVRFVVAAYNDTWLRDSGPIT...L
60 SALT.....E.GEKVHIVAYDEEEKERInk7dkGLNM..DKIDFFIAPTDDVWARDSGPIF...V
61 EQIL.....Y.FESVILCVDINDDEGMAl20ksYNQQ..YGLHIVRVPTNDTWARDFGGIS...V
62 SALT.....E.GEKVHIVAYDQEEKERInn7deGLNM..EKIDFFIAPTDDVWARDSGPIF...V
63 RALAgp...G.AERVRLMVVGDEAEAAA.....RALLsdTTVEIVRGQFGDIWLRDTGPIF...V
64 NAIA.....R.FEPVKMVVDPSAIASAK.....ALCG..PNIELIPLAVNDSWCRDSGPSF...V
65 NTVA.....R.YEPVTVLVSPADRTAAR.....EALD..PRIEVVEVPLDDAWLRDSGPTF...V
66 TAIL.....R.HERLIVVCPDRKRVFGLlp...PELH..HRLYCFELPSNDTWARDHGGIS...L
67 KELH.....Y.GETVHIVVYDEKEKVHVqs7eaKVDM..DKIDFLIEETDDVWIRDNGPIF...V
68 KAVAaqg..E.GEKVYLVAAHKEAADQAv....KMAG..SDIEVICHPFGDIWLRDNAPLF...V
69 RAIH.....E.STPVRILATGLVAEDCRkh7igLVES..DSLRIVDVPTNDCWIRDYGPTF...V
70 NAIA.....R.FEPVKLVVDPAALDRAG.....ELCA..GNVELIELAIDDSWCRDSGPSF...V
71 RTIA.....R.YQRCVVAAHHSQADAAR.....ELVG..ASVDVVPVAAEDNWLRDCGPIF...L
72 KVVS.....E.FQKVLLIA-PKQSDFEN.....FKDI..KNVEFFKCDTNDTWIRDFGAID...I
73 NAVA.....DsGQEVRLVVRDAANEMRAk....SLVS..GAVTLERRTYGDVWLRDTGPLV...V
74 KAIA.....P.TVKIDFLLNEPEEKVIIng7taGIPA..SQVRYHLVPHEDLWIRDMGPIF...A
75 IAFS.....T.YSDVWVLLHSSISKAQWl14anARRC..AVSVIDSIDYDDTWIRDYGPLT...T
76 ----.....-.-----------------.....----..----------------------...-
77 KAIG.....A.TEPVDMLVLPADLDAARa22aaGAGG..INLVPLADGFNDFWVRDTGCLF...V
78 KELA.....K.NDKVITIVASESQKNTVit7qsGVNL..SNCDFIIAKTDSYWTRDYAGWF...A
79 KELA.....K.NDKVITIVASESQKNTVit7qsGVNL..SNCDFIIAKTDSYWTRDYTGWF...A
80 ----.....-.-----------------.....----..----TSCFEYDDIWLRDVAPVVtnhL
81 ----.....-.-----------------.....----..--FHTSFFEYDDIWLRDVAPVVtnhL
82 ----.....-.-----------------.....----..---YTSFFEYDDIWLRDVAPVVtnhL
83 SAIS.....Q.FEPVTICVSSAQYTTAC.....HLLQnkPNIRIVEMSMNDSWFRDSGPTF...V
84 ----.....-.-----------------.....----..----------------------...-
85 ----.....-.-----------------.....----..----------------------...-
110 120 130 140 150
| | | | |
1 VRKRPVKLSSLNRNIAGIDWNFNAWGG.....ANDGCYNDWSHDLLVSRKILA.....LERIPRF
2 VRKRPVKLSSLNRNIAGIDWNFNAWGG.....ANDGCYNDWSHDLLVSRKILA.....LERIPRF
3 VRKRPVKLSSLNRNIAGIDWNFNAWGG.....ANDGCYNDWSHDLLVSRKILA.....LERIPRF
4 IDD--------KGDVRGVDWGFNAWGG.....FEGGLYFPWQRDDQVARKILE.....IERRARY
5 VRKRPVKLSSLNRNIAGIDWNFNAWVG.....ANDGCYNDWSHDLLVSRKILA.....LERIPRF
6 VND--------SGDVRGVDWSFNSWGG.....LVDGLYFPWDKDDQVAQKICE.....LERKDRY
7 VND--------SGDVRGVDWSFNSWGG.....LVDGLYFPWDKDDQVAQKICE.....LERKDRY
8 VND--------SGDVRGVDWSFNSWGG.....LVDGLYFPWDKDDQVAQKICE.....LERKDRY
9 IND--------RGELRGVNWEFNAWGG.....FDGGLYAPWNLDSQVGSKVLE.....IERCPRY
10 INN--------SGEVRGVNWDFNAWGG.....FDGGLYSPWNRDSQVGGKILE.....IERSPRY
11 VND--------KGDSRGVDWTFNAWGG.....LVDGLYFPWDKDDRVAQKVCE.....IEGRDRY
12 IND--------HGEVRGVDWGFNAWGG.....FDGGLYAPWNRDEELAAKVLE.....MERCQRY
13 VDD--------AGEVRGVDWTFNAWGG.....FAGGLYAPWNRDDQVARKILG.....IERCARY
14 KNK--------DGEIRGVDWVFNAWEG.....FKGGLYFPWDKDDAIARKVCE.....ICNIDYY
15 IND--------RGEVRGVNWEFNAWGG.....FDGGLYAPWNLDSQLGGKVLE.....IERCPRY
16 VND--------KGEMRGVDWGFNAWGG.....LLDGLYFPWDKDNQIAKKVCD.....IERLDYY
17 VND--------KGEMRGVDWGFNAWGG.....LLDGLYFPWDKDNQIAKKVCD.....LERLDYY
18 VDD--------KGDMRGVDWGFNAWGG.....LLDGLYFPWDKDNQIAKKVCE.....LERIDYY
19 VND--------KGDLRAVDWEFNAWGG.....LVDGLYFPWDQDALVARKVCE.....IEGVDSY
20 VDD--------KGDMRGVDWGFNAWGG.....LLDGLYFPWDKDNQIAKKVCE.....LERIDYY
21 IND--------KGELRANDWTFNAWGG.....LVDGLYFPWDQDDLVAQKVCE.....LERVDSY
22 ING--------AAERRAVDWQFNAWGG.....LNGGLYADWQQDEKVAVQVSD.....FLKNAHY
23 ING--------AAERRAVDWQFNAWGG.....LNGGLYADWQQDEKVAVQVSD.....FLKNAHY
24 VNQ--------AGERRGISWQFNAWGG.....EYNGLYDNWQQDDLVAGSVCD.....IIGIDYY
25 VNA--------EGECRGVDWGFNAWGG.....HNGGLYFPWDKDEQVAQQMLA.....QHGFARY
26 VND--------KGKKLAVDWAFNAWGG.....TYDGLYQDYEEDDQVASRFAE.....ALERPVY
27 VND--------KGKKLAVDWAFNAWGG.....TYDGLYQDYEEDDQVASRFAE.....ALERPVY
28 VRKGAPGLGITEKNIAGIDWEFNAWGG.....ATDGCYVDWSLDSYVAKKIVE.....IERIPRF
29 VND-------QSGEVRGVDFEFNAYGG.....LDGGLYYPWDKDDQIASKILE.....IERFDRY
30 IND--------HGEIRGVDWTFNAWGG.....LVDGLYFPWDQDDLVAQKICE.....IEHVDSY
31 VRD-----TPAGRELAATDWEFNAWGG.....KYP----PYDLDNQIPARMAA.....YLGVPRF
32 IRT-----QDGRRDKVIMNWEYNAWGG.....KYE----PYDDDNAVPERVAK.....AQGLPMV
33 IND--------SGEVRGVNWDFNAWGG.....FDGGLYAPWNRDSQVGGKILE.....IERAPRY
34 ERD---------GRPVLLDFGFNGWGL.....KFAADRDNLVTRRLRHLGIFG.....DIPAEM-
35 ERD---------GNPVLLDFGFNGWGL.....KFAADRDNLITGRLHRTGAFG.....--NAALE
36 TNG---------KNVKAISWDFNSWGG.....NFDGLYTTWKNDQKIAEYMAR.....ISNIPII
37 VNP------AAEQKKVIVDWGYNAWGG.....KYP----PYDLDDVIPTKIAQ.....MYNIPVF
38 TRG------EKDPEVALVNWRFNAWGG.....KF-----EWENDNRVPEYVAQ.....FLGMGHW
39 ETP---------AGLRLLDWGFNGWGL.....KFAANHDNQVTRRLWQQGIFG.....--TTPLE
40 EEN---------GKKRLLDFGFNGWGL.....KFASFLDNQANRALARKGIYQ.....---VPLE
41 LNG--------EGEAGLVDFNFNGWGG.....KQ-----QAGNDSRVAGVLSE.....RLEVRYI
42 KNA--------SGQLGGVSFNFNGWGN.....KQ-----EHDQDAEVAPFVAE.....RAGARLL
43 IGT--------NGDFRLLDFRFTGWGG.....KFEAKADDQLVSALHAKGLFK.....--NTQMH
44 LNG--------EGEAGLVDFNFNGWGG.....KQ-----QAGNDSRVAGVLSE.....RLEVRYI
45 KTG--------AGGMAAVDFNFNGWGG.....KQ-----AHGRDARVAGFVAG.....RAGALPL
46 IGI--------NGDFRLLDFRFTGWGG.....KFEAKADDQLVSALHANGLFK.....--NTQMH
47 IGI--------NGDFRLLDFRFTGWGG.....KFEAKADDQLVSSLHANGLFK.....--NTQMH
48 TDG--------RGGLAAVDWVFNGWGA.....QD---WARWEHDAEIARHVAD.....LAAAPVL
49 IGT--------NRDFRLLDFRFTGWGG.....KFEAKADDQLVSVLHANGLFK.....--NTQMH
50 TDG--------KGGLAAVDWTFNGWGA.....QS---WARWEHDAKIAAYVGD.....LAGAKTY
51 INE--------AGERRLLCLPFNGWGK.....KY-----QLAGDSDLAIRLAL.....LMGIPYG
52 TGP--------CRALAAVRFAFNGWGG.....KY-----VLDHDTEVAAAVAA.....TADLPTY
53 IDD--------KNGLGAVDFNFSGWGN.....KQ-----QHSKDAKIAKRVAA.....DAQATYQ
54 RQE---------AGFRLMDFRFTGWGG.....KFEASLDDQLVSSLDAAQVFV.....--PAQVE
55 IDT---------GNPSLLDFTFNGWGL.....KFASELDNLITGQAVKAGALK.....GQYIDCL
56 ENH---------GVLECLDFGFNGWGL.....KYP---SNLDNQVNFKLKSLG.....FLKHPLK
57 ENH---------GVLECLDFGFNGWGL.....KYP---SNLDNQVNFKLKHLG.....FLKHPLK
58 YDN--------NKNLKILDPAFNGWGK.....KT-----PYKNDARIRENVSK.....QAGIERI
59 RHG---------DGFRLMDFRFTGWGG.....KFEASLDDQLVSSLDAASVFV.....--PADVQ
60 YDN--------NKNLKILDPAFNGWGK.....KT-----PYKNDARIRENVSK.....QAGIERI
61 EAE---------GGIALFDFVFNGWGL.....KYPANYDNQITQNIVCEAFKNt10riFSSYRPI
62 YDS--------NKNLKILDPAFNGWGK.....KT-----PYKNDAQIRKNVSK.....QSGIERV
63 DDA---------GKAVAAGFKFNGWGG.....KY-----SLEGDDIVAEQIAA.....ASGAPLV
64 VHP--------EQGLAGVSWRFNAWGG.....KS-----AHDLDESLARRVLN.....HLGGECF
65 RGA---------QGPVAVDWTFNGWGA.....QS---WSRWEDDARVARFVAG.....RTGTPVS
66 LAD---------GRPMIADFAFNGWGM.....KFAAHHDNLITRRLHALGLFA.....EGVTLDN
67 KDK--------KGNLCLTHWIFNGWGE.....KY-----PYKKDAVMPAKISE.....MYSIPKV
68 KEG---------DKKALALFRFNGWGG.....KY-----NLDGDQTIGRDLAK.....DTALPVL
69 FGP--------DSEKIAVDWRFNAWGG.....KYE----PFDSDAAAGAEIAK.....IAGLKRL
70 CHP--------QLGLAGVSWRFNAWGG.....KS-----AYAQDASLARRILD.....GLGLECF
71 VSE--------QHGLGAAVFRFNCWGE.....KYQ----PYDGCQQAGQDIAR.....AAGAEIF
72 VEN---------GRLKALDFTFNAWGN.....KFQSELDNAVNSKLFKEKFKE.....----ELK
73 LDG--------AGRREARLFGFNGWGE.....KY-----LMPGDQEIGADLAK.....SAGLATH
74 VNA---------DQTQVVDFGFNAWSY.....LA-ATDPAAMTDEQVDRKVAG.....DLDLPIL
75 HSD-------------YVSFCFNGWGG.....KY-----PAALDTLVGKKLQP.....WLGDVVR
76 ------------------------WGR.....LVDGLYSPWDKDDAVARKVCE.....TLGDDSY
77 RDT------TNDNALNAVGFNFNGWGNa25rsKAGKFFQPFGRDNTVAGWMAQ.....RKGASLI
78 MYD--------TNKVGLVDFIYNR---.....-------PRPNDDEFPKYEAQ.....YLGIEMF
79 MYD--------TNKVGLVDFIYNR---.....-------PRPNDDEFPKYEAQ.....YLGIEMF
80 VKFKYRPNYLPDDQGRYLDQQFNKWLK.....KN-------------------.....--DFEYV
81 VKFKYQPNYLPDDQGRYLDQQFNKWLK.....KN-------------------.....--DFEYV
82 VKFKYRPNYLPGDQGRYLDQHFNKWLK.....KN-------------------.....--DFEYV
83 VLDRESSSGYEVHPVAGIDWIFNSWGG.....TEEGCYSDWS-----------.....-------
84 ---------------------------.....---------------------.....-------
85 ---------------------------.....---------------------.....-------
160 170 180 190 200 210
| | | | | |
1 QH.SMILEGGSIHVDGEGTCLVTEECLLNKNRNPHM.....SKEQIEEELKKYLGVQ..SFIWLP
2 QH.SMILEGGSIHVDGEGTCLVTEECLLNKNRNPHM.....SKEQIEEELKKYLGVQ..SFIWLP
3 QH.SMILEGGSIHVDGEGTCLVTEECLLNKNRNPHM.....SKEQIEEELKKYLGVQ..SFIWLP
4 RTdDFVLEGGSIHVDGEGTLITTEECLLNHNRNPHL.....SQAEIERTLRDYLAVE..SIIWLP
5 QH.SMILEGGSIHVDGEGTCLVTEECLLNKNRNPHM.....SKEQIEEELKKYLGVQ..SFIWLP
6 RLaDFVLEGGSIHVDGEGTLVTTEECLLSEGRNPQL.....SKQQIEMVLKEYLNLE..KIIWLK
7 RLaDFVLEGGSIHVDGEGTLVTTEECLLSEGRNPQL.....SKQQIEMVLKEYLNLE..KIIWLK
8 RLaDFVLEGGSIHVDGEGTLVTTEECLLSEGRNPQL.....SKQQIEMVLKEYLNLE..KIIWLK
9 ATqGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHL.....TREQIEAVLSDYLAVD..KIIWLP
10 RTeGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHL.....GREEIEAMLSENLSVD..KIIWLP
11 RLdDLVLEGGSTHVDGEGTLLVTEECLLSDGRNPQL.....SKEQIESILKEYLNVE..KIIWLK
12 QTeGFVLEGGSIHVDGEGTVITTEECLLNRNRNPHL.....SREQIEAVLRDHLAVD..TVVWLP
13 RTeGFVLEGGAIHVDGEGTLLTTEECLLNPNRNPHL.....SREEIEAVLAGHLAVE..RVIWLP
14 RT.DFVLEGGSIHTDGDGTLYTTEECLLNENRNPDL.....TKEQIEENLKEYCGVE..KVIWLP
15 VTeGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHL.....TREQIETILGDYLAVD..KVIWLP
16 SQkDFILEGCSIHVDGEGTLVTTEECLLSEGRNPNL.....TKIEIEQTLKKYFHVQ..KVIWLK
17 SQkDFILEGCSIHVDGEGTLVTTEECLLSEGRNPNL.....TKIEIEQTLKKYFHVQ..KVIWLK
18 SQkDFILEGCSIHVDGEGTLVTTEECLLSEGRNPNL.....TKIEIEQTLKKYFHAQ..KVIWLK
19 KTkDFVLEGGSIHVDGEGTVLVTEMCLLHPSRNPHL.....TKEDIEDKLKDYLNCV..KVLWVK
20 SQkDFILEGCSIHVDGEGTLVTTEECLLSEGRNPNL.....TKIEIEQTLKKYFHAQ..KVIWLK
21 RTdDFVLEGGSFHVDGQGTVLTTEMCLLSEGRNPHM.....SKEDIENKLKEHLNAE..KILWLG
22 SA.PLILEGGSIHTDGEGTLLTTAECLLNPNRNPHL.....NQAQIEQLLCDYLGVT..HFIWLQ
23 SA.PLILEGGSIHTDGEGTLLTTAECLLNPNRNPHL.....NQAQIEQLLCDYLGVT..HFIWLQ
24 RA.PFVLEGGAIHTDGEGTLYTTEECLLSPGRNPQL.....SKAQIEEQLKVYLGIE..KIIWLP
25 RA.PLILEGGSIHVDGEGTCMTSAECLLNANRNPEL.....TKEQIEGLLRDYLNVK..QFIWLQ
26 DAkPFVLEGGAIHSDGQGTILVTESCLLSPGRNPNL.....TKEEIENTLLESLGAE..KVIWLP
27 DAkPFVLEGGAIHSDGQGTILVTESCLLSPGRNPNL.....TKEEIENTLLESLGAE..KVIWLP
28 PH.TMVLEGGSIHVDGEGTCITTEECLLNPNRNPNM.....TKLEIENELKDFLGVA..KVIWIP
29 RA.PLIAELGGIQSDGQGSILTTEQCLLNRNRNQHL.....GKDEVTRRLTDYLGAE..QVIWLP
30 RTdDFVLEGGSFHVDGQGTVLTTEMCLLSEGRNPQL.....SKEAIEQKLCDYLNVE..KVLWLG
31 CG.GMVLEGGSIDVDGNGLLLTSEQCLLNPNRNPHL.....DRAAIEQRLREMLGVH..TILWLG
32 ST.GMVLEGGAIDVNGAGLLLTTTACLLNPNRNPSL.....GKAEIEAQLRRYLGIE..KVLWLG
33 RTqGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHL.....DRAAIEAVLADHLAVD..KIIWLP
34 -V.GLVLEGGSIESDGRGTVLTTAECLLNPNRNPHL.....SRAEIEEALARYLGTE..RVLWLE
35 TV.GLILEGGSIESDGNGTILTTAECLLNPNRNPHL.....SQEQIEISLKEQFGAD..RILWLE
36 KTpGFVLEGGSIHVDGEGTLITTKECLLSTGRNPTM.....SQQDIEYYLKEYLNVE..KIIWLE
37 HP.GIVMEGGSVEFNGRGTLLTSTSCLLNPNRNPSK.....SREQIEEYLEDYYGVE..HILWLG
38 DR.PEVLEGGGLEIAGDGAALTTRSCFLTDTRNPGL.....SEEGYTFLLSDQLGVK..KLHWLD
39 TV.PLIFEGGSIESDGRGTLLTTSQCLLEANRNPGL.....SREAIAQIIQRQLGGD..RLLWLE
40 TK.NLILEGGSIESNGAGLILTNTQCLLEANRNPEY.....SKEKIESILTQELGAK..KVLWCH
41 AS.QLTGEGGGIEVDGRGTAILTESCWLNDNRNPGM.....DKGQVEAELKALLGLR..KIVWLP
42 DT.RLVLEGGGIEVDGEGTAIITRSCVLNSNRNPGV.....GQAQCEAELSRLLGLK..KIIWLP
43 SI.NFALEGGAIETDGAGTLLTTWRCLHE--RHPQR.....TRTTLDANLTAWLAQN..RVLWLE
44 AS.QLTGEGGGIEVDGRGTAILTESCWLNDNRNPGM.....DKGQVEAELKALLGLR..KIVWLP
45 RS.GLVLEGGGIEVDGEGTAIITESCVLNANRNPGW.....SKAQCEGELRRVLGVE..KVIWLP
46 SI.NFALEGGAIETDGAGTLLTTWRCLHE--RHPQR.....TRTTLDANLTAWLAQN..RVLWLE
47 SI.NFALEGGAIETDGAGTLLTTWRCLHE--RHPQR.....TRTTLDANLTAWLAQN..RVLWLE
48 SS.PLVNEGGAIHVDGEGTVLLTDTVQLGSGRNPGW.....SREEVEAEIHAKLGTT..TAIWLP
49 SI.NFALEGGAIETDGAGTLLTTWRCLHE--RHPQR.....TRKTLDANLTAWLAQN..RVLWLE
50 AS.KLVNEGGAIHVDGEGTVLLTETVQLGAERNPGW.....TREQVETEIHAHLGTS..KAIWLP
51 SV.PLFLEGGAIEVDGEGTCLTTRQCLLNPNRNPYL.....SSAEVEARLKPALGVS..KILWIE
52 SF.PWVLEGGSVEVDGEGTCLTTRQCLLNPNRNPGM.....DSKAIEQGLKEALGVR..KVLWLD
53 RS.ELVGEGGGIEVDGHGTAIMTESCWVNENRNPGW.....SKADVEAELKARLGLR..KIIWLP
54 TV.DFALEGGAIETDGAGTLLTTWKCLHE--RHPQR.....TRESLSSDLATWLAQE..RVLWLD
55 --.DFVLEGGSIESDGMGTLLTTTECLLSPHRNGKL.....NQVEIEEYLKSTFHLQ..KVLWLD
56 TM.PYILEGGSIESDGAGSVLTNTQCLLEKNRNPHL.....NQNGIENMLKKELGAK..QVLWYS
57 TM.PYILEGGSIESDGAGSILTNTQCLLEKNRNPHL.....NQNGIETMLKKELGAK..QVLWYS
58 DWgKFVLEGGAIELDSNGTALLTRSAVTNKNRNPDL.....SEKEIEKYISD-LGVS..NFIWLD
59 TV.DFALEGGAIETDGAGTLLTTWKCLHE--RHPQR.....SRDSLSSDLATWLAQD..RVLWLD
60 DWgKFVLEGGAIELDSNGTALLTRSAVTNKNRNPDL.....SEKEIEKYISD-LGVT..NFIWLD
61 KT.DMILEGGSIESNGAGVLLTNTQCLLEKNRNSHL.....SQDEIESKLKEYFGLD..SVLWLT
62 DWgKFVLEGGAIELDSNGTALLTRSAVTNKNRNPDL.....SEKEIEKYISD-LGVS..NFIWLD
63 RN.DFILEGGALDHDGNGTILTTRQCLLNDNRNPGW.....DEATANAALTEALGAK..KVLWLG
64 GT.ALSNEGGAIHVDGEGTLITTESVLLNPNRNPGV.....SKAEMEEIFSRLLGVK..KTIWLP
65 SS.PLTQEGGGFHVDGAGTVLLTDTVQLDPGRNPGW.....TREQVEAEVHAQLGTT..TAIWLP
66 RL.AFVLEGGALETDGEGTLLTTDSCLFEPNRNAGL.....SRTAIIDTLKESLGVS..RVLSLR
67 KS.SVCLEGGGIEINGNGTLMAAKTSIINENRNPTL.....SQEEIEIELTKYLGVT..NFIWIT
68 EK.NWVLEGGSIDGDGHGLVVTTEECLLNPNRNPEL.....SRGDIARHLRNDLGYD..RVLWLR
69 DG.GLTMEGGALETDGAGRLLVNPGCLVDPARNPGV.....SKEQVSQRLNQCLGVE..EIVWVD
70 GV.PLANEGGAIHVDGEGTLITTESVLLNANRNPGL.....SKAEIEALFARLLGVT..RTIWLP
71 NS.HMVLEGGSFYVDGQGTLVTTESCLLHPNRNPHL.....SRAEIEAELRRMLGVE..KIIWLP
72 KV.DFILEGGSIDFNGEGVMLTSSHCLLNENRNSHL.....NKTQIDTKLKEIFGLK..QIIWLE
73 GKaDWILEGGALDGDGTGLVATTEQCLLNPNRNPHL.....SRGDLEARLLRDLGYD..RVLWLG
74 RS.SLISEGGNREFNGKGTLMLTEAVELQ--RNPGL.....TKEKIETELKRVFNLK..KVIWLQ
75 ES.EYFFEGGALEINDSGVLLANKDCVIDTHRNPGL.....NQAAVEAILAKELGVK..AFAWLE
76 RA.PIVLEGGSIHVDGEGTLYTTEECLLHPSRNPDL.....TREEIEDVLKVTLSIE..KVIWIP
77 RS.TLTLEGGAIEFDGDATAILTESSVLHVNRNPQLf16ptAKDTVLAELQRTLGVR..KIIWLP
78 GM.KLKQTGGNYMTDGYGSAVQSHIAYTE---NSSL.....SQAQVNQKMKDYLGIThhDVVQDP
79 GM.KLKQTGGNYMTDGYGSAVQSHIAYTE---NSSL.....SQAQVNQKMKDYLGIThhDVVQDP
80 KS.PLILDGGNLIWNKKDTVILTERIFDD---NDDW.....TEEEIIEQLEWDLDVS..RVIIIP
81 KS.PLILDGGNLIWNKKDTVILTERIFDD---NDDW.....TEEEIIEQLEWDLDVS..RVIIIP
82 KS.PLILDGGNLIWNKKDTIIVTERIFDD---NDDW.....TEEEIIEQLEWDLDVS..RVIIIP
83 --.---------------------------------.....----------------..------
84 --.---------------------------------.....----------------..------
85 --.---------------------------------.....----------------..------
220 230 240 250
| | | |
1 R..GL...YGD.....ED.....TNGHIDNMCCFARPGVVLLS.....WTDDETDPQY..ERSVE
2 R..GL...YGD.....ED.....TNGHIDNMCCFARPGVVLLS.....WTDDETDPQY..ERSVE
3 R..GL...YGD.....ED.....TNGHIDNMCCFARPGVVLLS.....WTDDETDPQY..ERSVE
4 N..GL...Y-N.....DE.....TDGHVDNFCCYARPGEVLLA.....WTDDQDDPNY..LRCQA
5 R..GL...YGD.....ED.....TNGHIDNMCCFARPGVVLLS.....WTDDETDPQY..ERSVE
6 R..GI...Y-L.....DE.....TNGHVDNIFNYVRPGVVALA.....WTDDETDPQY..EISKE
7 R..GI...Y-L.....DE.....TNGHVDNIFNYVRPGVVALA.....WTDDETDPQY..EISKE
8 R..GI...Y-L.....DE.....TNGHVDNIFNYVRPGVVALA.....WTDDETDPQY..EISKE
9 D..GL...F-N.....DE.....TDGHVDNFCCYIRPGEVLLA.....WTDDPEDPNY..PRCHA
10 D..GL...F-N.....DE.....TDGHVDNFCCYVRPGEVLLA.....WTDDPQDPNY..PRCQA
11 K..GI...Y-L.....DE.....TNGHVDNIANFVKPGQVVLA.....WTDDQSDPQY..AISKE
12 D..GL...Y-N.....DE.....TDGHVDNFCCYVRPGEVLLA.....WTDDSNDPNY..ARCHA
13 Q..GL...Y-N.....DE.....TDGHVDNFCCFVRPGEVLLA.....WTDDPQDPNH..PRCRA
14 L..GV...Y-N.....DE.....TNGHVDNLLNVVSPGHVVLT.....WTDDTTDPQY..ERSKL
15 E..GL...F-N.....DE.....TDGHVDNFCCYIRPGEVLLA.....WTDDPEDPNY..SRCHA
16 H..GF...Y-L.....DE.....TNGHVDNIFNFVAPGEVVLS.....WTDNKSDPQY..EISRE
17 H..GF...Y-L.....DE.....TNGHVDNIFNFVAPGEVVLS.....WTDNKSDPQY..EISRE
18 H..GF...Y-L.....DE.....TNGHVDNIFNFVAPGEVVLS.....WTDNKSDPQY..EISRE
19 D..GI...D-P.....YE.....TNGHIDDVACFIRPGEVACI.....YTDDKEHPFY..QEAKA
20 H..GF...Y-L.....DE.....TNGHVDNIFNFVAPGEVVLS.....WTDNKSDPQY..EISRE
21 D..GI...D-P.....EE.....TNGHVDDVACFVAPGEVACI.....YTEDEKSPFY..EAAQD
22 D..GV...Y-N.....DE.....TDGHIDNMCCFVRPGEVALH.....WTDDQQDPQY..ARSVA
23 D..GV...Y-N.....DE.....TDGHIDNMCCFVRPGEVALH.....WTDDQQDPQY..ARSVA
24 N..GL...F-N.....DE.....TDGHVDNLMHVIAPGKVVLS.....WTDDPSDPQY..ALSRQ
25 D..GV...Y-M.....DE.....TDGHIDNMCCFARPGEVILH.....WTDDESDPQY..PRSKA
26 Y..GI...Y-Q.....DE.....TNEHVDNVVAFVGPAEVVLA.....WTDDENDPQY..AMSKA
27 Y..GI...Y-Q.....DE.....TNEHVDNVAAFVGPAELVLA.....WTDDENDPQY..AMSKA
28 H..GL...YGD.....DD.....TNGHVDNLCCFIKPGVVLLS.....WTDDENDPQY..QRSVD
29 R..GC...K-F.....DE.....TDGHVDDLACFVRPGEVVLQ.....WTDNRDDPQW..EIYQE
30 D..GI...D-P.....EE.....TNGHVDDVACFIAPGEVACI.....YTEDQNSPFY..EAAQD
31 E..GI...V-G.....DD.....TDGHIDDLARFVAPGVVVTV.....VEDDPLDENY..HVLQD
32 D..GI...A-G.....DD.....TDGHVDDMARFVNENTVVIA.....VEEDPEDENY..KPLRE
33 D..GL...F-N.....DE.....TDGHVDNFCCYVRPGEVLLA.....WTDDPQDPNY..PRCHA
34 N..GF...LAG.....DD.....TDSHVDTLARLAPDDTIVYV.....RCDDATDEHY..AALFM
35 N..GW...LAG.....DD.....TDSHIDTLARLAPDDTIVYV.....RCDDAADEHY..PALFL
36 Y..GV...A-D.....DE.....TNGHVDNMACFSRPGEVILA.....WTDDPKHPQY..ERSKN
37 E..GI...V-G.....DD.....TDGHIDDITRFVNEDTVVTV.....VEENKSDDNY..FLLKD
38 G..GL...E-N.....DH.....TDGHIDTITRFAAENVIVTS.....VEADPNDANH..AVMQR
39 H..GH...LEG.....DD.....TDAHIDTLVRIAPNDTLIYV.....ACDDPSDSHA..AELTA
40 H..GY...LAG.....DD.....TDSHIDTLARFVGENRIVYL.....KCEDESDEHY..KELKQ
41 -..GI...RGR.....DI.....TDAHVDFYARFVRPGVVIAN.....LDNDPDSYDY..AVTRE
42 -..GI...AGK.....DI.....TDGHTDFYARFTSPGVVVAG.....LDTDPSSYDH..AVTRQ
43 H..GY...LEG.....DD.....TDAHIDTLARFASTDSIVYQ.....SCDNTTDSHY..AELQA
44 -..GI...RGR.....DI.....TDAHVDFYARFVRPGVVIAN.....LDNDPDSYDY..AVTRE
45 -..GV...AGR.....DI.....TDGHTDFYARFARPGVVVAG.....LETDPASYDY..QVTRR
46 H..GY...LEG.....DD.....TDAHIDTLARFASTDSIVYQ.....SCDNTTDSHY..AELQA
47 H..GY...LEG.....DD.....TDAHIDTLARFASTDSIVYQ.....SCDNTTDSHY..AELQA
48 H..GLagdYGR.....YG.....TQGHVDIVAAFARPGTVVVH.....SQRDPRHPDH..ERSQL
49 H..GY...LEG.....DD.....TDAHIDTLARFASTDSIVYQ.....SCDNTTDSHY..AELQA
50 R..GL...TGD.....YPphgfgTLGHVDIVAAFARPGVVVAH.....HQPDPAHPDH..EVSKE
51 S..GL...V-N.....DH.....TDGHIDTLVRFVAPATVVCM.....LAESPEDPNC..DVLRT
52 E..GL...L-N.....DH.....TDGHIDTIARFAAPGVVVCM.....-QAAPDDPNA..PVLDN
53 -..GI...KGK.....DI.....TDAHVDFYARFVTPGVVIAN.....LDTDPRSYDN..KVTLA
54 H..GY...LEG.....DD.....TDAHIDTLARFAGPDAIVYQ.....GCDVASDSHY..VELQA
55 H..GY...LAG.....DD.....TDSHIDTLARFCSTDTIAYV.....KCDNTEDEHY..EALHA
56 Y..GY...LKG.....DD.....TDSHTDTLARFLDKDTIVYS.....TCEDENDEHY..TALKK
57 Y..GY...LKG.....DD.....TDSHTDTLARFLNKDTIVYS.....ACEDENDEHY..TALKK
58 -..GV...PNL.....DI.....TDFHIDGFAKFHNKSTIVTM.....KEDDL--AEW..GLSNK
59 H..GY...LEG.....DD.....TDAHIDTLARFAGADAIVYQ.....GCAVPSDSHY..AELQA
60 -..GV...PNL.....DI.....TDFHIDGFAKFHNKSTIVTM.....KEDDL--AEW..GLSNK
61 Q..GY...LAG.....DD.....TDSHIDTLARFISEDTIAYI.....TCDDKQDEHF..ESLKS
62 -..GV...PNL.....DI.....TDFHIDGFAKFHNKSTIVTM.....KEDDL--AEW..GLSNK
63 K..GL...K-N.....DH.....TDGHVDNLARFVAPGVVACP.....MGYGLDDPNA..DIYGD
64 GdpDY...VTG.....DM.....TDGHVDGVCAFARPGVLLVD.....ATHDCSSVYA..EVVRE
65 R..GLtadYGE.....FG.....TRGHVDIVAAFTPSGAVLVH.....TQPDPGHPDH..AVTQE
66 H..GA...LAG.....DD.....TDGHIDTLARFVDTRTIVYV.....RSEDPSDEHY..SDLTA
67 G..IRgedNYD.....ED.....TDYHIDGAARFVNENTILYE.....YDPFGEGEPYllDAYEK
68 K..GL...H-N.....DH.....TDGHVDNLARFVGENHLVVP.....IATDQDDPNR..EVYDQ
69 G..GA...PAG.....DD.....TDGHIDQIARFLNRENVVCA.....VASSEVDENY..PGLEA
70 G..DPdr.VTG.....DM.....TDGHVDGVCAFARPGALLLD.....ATCDTTSAYA..EVVRE
71 -..GN...PDE.....VE.....TNGHVDGIASFIAPGRMLCQ.....TALPEQGDYF..HVMRE
72 N..GF...IKG.....DD.....TDHHIDTLARFIDKNTIAHC.....ICEDEEDEHY..LPLQK
73 D..GL...I-N.....DH.....TDGHVDNLARFVGPNRLALP.....RATGPNDPNA..AIYAD
74 E..GV...IDD.....ELs15laTGGHIDEYARFVDSNTILLAev7erASDPLAAINY..QRLEE
75 G..IQ...LTG.....DD.....TDGHIDTIARYVANDSVVYS.....-GPNPSHPDA..AALLA
76 Q..GL...Y-N.....DE.....TNGHVDNLIHVVRPGEIALT.....WCDDETDPQY..LISRK
77 G..TA...TYPr18etDI.....TNGHVDFYARFLAPGVVACC.....YDASNSTGER..ALTDA
78 N..GE...YIN.....--.....---HVDCWGKYLAPNKILIR.....KVPD-NHPQH..QALED
79 N..GE...YIN.....--.....---HVDCWGKYLAPNKILIR.....KVPD-NHPQH..QALED
80 -..--...AEE.....GD.....VLAHADGMVKFIDEHTMFIS.....--DFLGDHEF..RYSVE
81 -..--...AEE.....GD.....VLAHADGMVKFIGEHTMFIS.....--DFLGDDEF..RYHVQ
82 -..--...AEE.....GD.....VLAHADGMVKFIDEHTMFIS.....--DFLGDHEF..RYHVQ
83 -..--...---.....--.....--------------------.....----------..-----
84 -..--...---.....--.....--------------------.....----------..-----
85 -..--...---.....--.....--------------------.....----------..---EK
260 270 280 290 300 310
| | | | | |
1 ALSVLSNSIDARGRKIQVIKLYIPE.PLYMTEEESSGITQDGEAIPRLAGT.....RLAASYVNF
2 ALSVLSNSIDARGRKIQVIKLYIPE.PLYMTEEESSGITQDGEAIPRLAGT.....RLAASYVNF
3 ALSVLSNSIDARGRKIQVIKLYIPE.PLYMTEEESSGITQDGEAIPRLAGT.....RLAASYVNF
4 ALRVLEESRDAKGRKLVVHKMPIPG.PLYATQEECDGVDIVEGSQPRDPSI.....RLAGSYVNF
5 ALSVLSNSIDARGRKIQVIKLYIPE.PLYMTEEESSGITQDGEAIPRLAGT.....RLAASYVNF
6 CFDILSNETDAKGRKLEVHKINVPK.PILITDEESKGVDAVEGTLPREEGD.....RLAASYINY
7 CFDILSNETDAKGRKLEVHKINVPK.PILITDEESKGVDAVEGTLPREEGD.....RLAASYINY
8 CFDILSNETDAKGRKLEVHKINVPK.PILITDEESKGVDAVEGTLPREEGD.....RLAASYINY
9 ALSILENTRDAQGRAFIVHKMPIPG.PLFATEEECAGVDQVHGSQERNPSV.....RLAGSYVNF
10 AMKVLESSTDAKGRPFTVHKMPIPG.PLFATEEECAGVDPVDGTQERNPSV.....RLAGSYVNF
11 NYDMLINETDAKGRKLQVEKLYLPK.PILITEAESQGVDTVDGTLPRLAGD.....RLAASYVNY
12 AMDVLKNTRDAKGREFIVHKMPIPG.PLFATAEECAGVDQVAGSQERDPSV.....RLAGSYVNF
13 ALEVLERVRDARGRALRVQRMPIPG.PLHASAEECAGVDPAADSQPRDPSI.....RLAASYVNF
14 AYDILTNTLDAKGRKIKVTKLHQPG.PLFITKEEAEGIDVCDTM-SREPEQ.....RMPASYANY
15 ALSILENTLDAKGRAFIVHKMPIPG.PLFATEEECAGVDQVHGSQERNPSV.....RLAGSYVNF
16 CYDILANQTDAKGRTFIIHKLHCPD.PVLITQTESEGVEAINGTFPRQAGD.....RLAASYVNY
17 CYDILANQTDAKGRTFMIHKLHCPD.PVLITQTESEGVEAINGTFPRQAGD.....RLAASYVNY
18 CYDILANKTDAKGRTFIIHKLHCPD.PVLITQTESEGVEAINGTFPRQAGD.....RLAASYVNY
19 AYDFLSQQTDAKGRPLKVHKMCVTK.EPC-YLQEAATIDYVEGSIPREEGE.....MAIASYLNF
20 CYDILANKTDAKGRTFIIHKLHCPD.PVLITQTESEGVEAINGTFPRQAGD.....RLAASYVNY
21 AYKRLNQMTDAKGRQLKVHKLTCPA.KNV-TIKKQFRIDTVEGTMPREDGD.....ICIASYMNF
22 AFEVLSNTVDAKGRKLKIWKLPAPG.PLYNTEEETFDV-LTSDAVPRTAGE.....RLAGSYVNF
23 AFEVLSNTVDAKGRKLKIWKLPAPG.PLYNTEEETFDV-LTSDAVPRTAGE.....RLAGSYVNF
24 AEQVLKSQHDAKGREIEIVRLPLPG.PLHYSEREANGIDASSGMS-RQAGE.....RLSASYANF
25 ALEVLQNTVDAQGRKLKIHLLPQPG.PLYCSEEESKGVT-EGTGVPRTAGE.....RLAGSYVNF
26 DLELLEQETDAKGCHFTIHKLPIPAvRQVVTEEDLPGYIYEEGEEERYAGE.....RLAASYVNF
27 DLELLEQETDAKGCHFTIHKLPIPAvRQVVTEEDLPGYIYEEGEEKRYAGE.....RLAASYVNF
28 ALSTLSKSVDAKGRQIEVVKIHVPG.PLYMTKEESEGVVKTEHAIPREPGT.....RLAASYVNF
29 AYDILRSTRDSRGRELIVHKLPQPD.VLEWTAEEAEGLDQQDSTHTRQAGT.....KICASYINY
30 AYQRLLKMTDAKGRQLKVHKLCCPV.KNV-TIKGSFKIDFVEGTMPREDGD.....ICIASYMNF
31 NLRRLQLMRDAAGRPLTVLTIPMPP.PVV------------------FQGQ.....RLPASYANF
32 NYELLKTMTGLDGKPLNIVKLPMPE.PVY------------------YDGE.....RLPASYANF
33 AMDVLQNSTDAKGRAFIVHKMPIPG.PLYATEEECAGVDPVDGSQERNPSV.....RLAGRNVNF
34 MEKELANLRTREGSPYRLIPLPWPR.ACF-----------------DHEGQ.....RLPATYANF
35 MEKELKAMRTSEGSPYRLIPLPWPR.PCH-----------------DEDGE.....RLPATYANY
36 AYKLLTKERDAKGRKLIIHKIHIPS.DMFITEEEATGVVNSGLAVPRRAGD.....RLAASYVNF
37 NLKDLHKMRLENGKQLNVIELPMPS.AVI------------------YDDQ.....RLPASYANF
38 NLATLRELRTPGGDFYQIVELPLPA.HRL-----------------EGAEG.....RLPPTYANF
39 LEAELKALRAADGQPYHLIPLPWPQ.PCF-----------------DADGQ.....RLPTTYANY
40 MEEELKELRGVDGEPLELIPLPFTK.AIY------------------YDGE.....RLPASYANF
41 HLEILRTATDADGRALQVHTLSPPL.KPR--------------RDYSRNNP.....DFAAGYINY
42 HLEILRKSTDAKGRPLKVVVLPGPK.SVR----------------HQYENE.....EFAAGYINF
43 MANELTALRTTEGRPYRLFPLPWTK.PIL------------------DQDR.....RLPASYANF
44 HLEILRTATDADGRALQVHTLSPPL.KPR--------------RDYSRNNP.....DFAAGYINY
45 HLAMLRQARDARGRKLEVVAIPGPD.RVR----------------PEYEDD.....EMAAGYINF
46 MANELTALRTTEGRPYRLFPLPWTK.PIL------------------DQDR.....RLPASYANF
47 MANELTALRTTEGRPYRLFPLPWTK.PIL------------------DQDR.....RLPASYANF
48 YLEILRGRTDARGRRLEVVEVPAPT.VLK-----------------DEEGE.....WADYSYINH
49 MANELTALRTTEGRAYRLFPLPWTK.PIL------------------DQDR.....RLPASYANF
50 VIGLLKAATDAHGRRIEVVEVPAPT.VLE------------------ADGH.....WADYSYINH
51 IYEQLQTLTDAKGRSLEVIPVPSPG.RVT-----------------SQKGE.....ILPASYVNF
52 IAATLAGFTDAAGRMLTVVRVPSPG.RVV-----------------DDNGE.....VMPASYVNF
53 HLEILKKATDADGRPLQIHTVSPPL.KPR-------------KTKFNKDND.....DFAAGYINY
54 MGAELAALRKADGQPYRLFVLPWAQ.PIL------------------DEGR.....RLAASYANF
55 MEEQLKTFRTLAGEPYRLLALPMAD.KVE------------------EDGE.....RLPATYANF
56 MQEELKTFKKLDGTPYKLIPLEIPK.AIF-----------------DENQQ.....RLPATYVNF
57 MQEELKTFKKLDGTPYKLIPLEIPK.AVY-----------------NENQQ.....RLPATYVNF
58 DMDTLLDAKNAAGKKYKYEYLPLSK.EKV--------------VLENGKTL.....DYKGSYINY
59 MGEELAALRKADGQPYRLFVLPWAE.PIL------------------DQGR.....RLAASYANF
60 DMDTLLDAKNALGKKYKYEYLPLSK.EKV--------------VLENGKTL.....DYKGSYINY
61 MEAELRALKQSNGEPYKLIPLPFTQ.AIY-----------------DEQGQ.....RLPASYANF
62 DMDTLLDAKNASGQKYKYEYLPLSK.EKV--------------ALENGKTL.....DYKGSYINY
63 TAKMLAGMTDSRGSPLQVVRIPSPG.KLL-----------------DEDGE.....PIPASHMNF
64 NRRALELATDAQGRKFELIELYEAT.DAV-----------------DTEAE.....VFCASYTNF
65 VTEVLRGARDARGERLEVVELLAPE.RHE------------------VDGE.....LVDHSYVNH
66 MEQELKELRRPDGQPYRLVPLPMAE.ALY------------------DGAD.....RLPATYANF
67 HYQELRQARNLDGKPFQLIPVPVTR.KVV-------------------KEA.....ECKGSYLNF
68 AAQIATEF------GVKVTRIPSTG.RIT------------------IDDE.....VVPASYMNF
69 NYRKLRLWSRQTEPAVTIHRLPTPP.PRE------------------VDGA.....AVPQSYCNF
70 NRRALELALDARGRRFELIELFDAG.EVA------------------PEEG.....VFCASYTNF
71 NRRALELATDAAGRRFELLDLPSPI.VTE-----------------RFGSE.....RYCDCYANY
72 MKEELKKT------GFDLLELPIPK.PLY------------------YEER.....RLGATYANF
73 ARARALDA------GVEVVEVPSPG.RIE------------------WGDM.....VQPASYMNF
74 NLKILQAATDQDGKPFRIVRIPAAK.PIYVNMTKEDAVFQALQELTFEDGTv10ktILAASYLNF
75 LKSQISALAAVH--NWQLAELPTPI.VYS----------------QVEEGQ.....LLPATYANF
76 AMDVLLTETDAKGRQIKIHKLPMPG.PLYISEDEANGVDVSEGM-ERVPGE.....RLAGSYANY
77 NRQRLAGETDANGRPLQIVELVPPV.NFG---------TSAGTSLNDRQMT.....NFAAGYINF
78 MAAYFAAQTCAWGTKYEVYRALATN.EQP----------------------.....-----YTNS
79 MAAYFAAQTCAWGTKYEVYRALATN.EQP----------------------.....-----YTNS
80 ----------------EIIQEQMPE.AEFIVVPSS----YTEKGQYDQEIA.....SAKGLYINM
81 ----------------EIIQEQMPE.AEFIVVPSS----YTEKGQYDQEIA.....SAKGLYINM
82 ----------------EIIQEQMPE.AEFIVVPSS----YTEKGQYDQEIA.....SAKGLYINM
83 -------------------------.-------------------------.....---------
84 --SELQELRTLEGNPYRLLRLPMPD.AIY------------------DGED.....RLPATYANF
85 HYQELRQAKNIDGKPFQLIPVPVTR.KVV-------------------KEA.....DCKGSYLNF
320 330 340 350 360 370
| | | | | |
1 Y.IANGGIIAPQFGDP.....IRDKEAIRVLSDTFPHHSVVGIENA.REIVLAGGNIHCITQQQP
2 Y.IANGGIIAPQFGDP.....IRDKEAIRVLSDTFPHHSVVGIENA.REIVLAGGNIHCITQQQP
3 Y.IANGGIIAPQFGDP.....IRDKEAIRVLSDTFPHHSVVGIENA.REIVLAGGNIHCITQQQP
4 L.IVNGGIIAPSFDDP.....-KDAEARAILQRVFPEHEVVMV-PG.REILLGGGNIHCITQQQP
5 Y.IANGGIIAPQFGDP.....IRDKEAIRVLSDTFPHHSVVGIENA.REIVLAGGNIHCITQQQP
6 Y.TANGGVVFPLFGDP.....-NDELAREKLRQLYPNCEVVGV-KA.REILLGGGNIHCITQQVP
7 Y.TANGGVIFPLFGDP.....-NDELAREKLQQLYPNCEVVGV-KA.REILLGGGNIHCITQQVP
8 Y.TANGGVVFPLFGDP.....-NDELAREKLQQLYPNCEVVGV-KA.REILLGGGNIHCITQQVP
9 L.IVNGGIIAPSFDDP.....-MDEKAREILQKLFPEHEVVMA-PG.RELLLGGGNIHCLTQQQP
10 L.IVNGGIIAPSFDDP.....-MDAPAREILQNLFPQHEVVMV-PG.RELLLGGGNIHCLTQQQP
11 Y.TANGGIVFPLFNDP.....-MDEKAQEILQKLYPDRKIVGV-PA.REILLGGGNIHCITQQIP
12 L.IVNGGIIAPSFDDP.....-ADAEARAILARIFPDHEVVMI-PG.RELLLGGGNIHCLTQQQP
13 L.IVNGGIIAPAFDDP.....-RDAEAEALLRQSFPGREVLML-PG.REILLGGGNIHCITQQQP
14 Y.IANNAIILPIFGDK.....-YDDLAVKTLQSVYPNHKIETV-MA.REILLGGGNIHCITQQQP
15 L.IVNGGIIAPSFDDP.....-MDEKAREILQKLFPEHEVVMA-PG.RELLLGGGNIHCLTQQQP
16 Y.TANGAIIFPLFDDP.....-KDKDAQELLEQLYPDRKIVGI-KA.REILLGGGNIHCITQHLP
17 Y.TANGAIIFPLFDDP.....-KDKDAQELLEQLYPDRKIVGI-KA.REILLGGGNIHCITQHLP
18 Y.TANGAIIFPLFDDP.....-KDKDAQELLEKLYPDRKIVGI-KA.REILLGGGNIHCITQHLP
19 L.IVNGGIILPQYGDE.....-NDQLAKQQVQEMFPDRKVVGV-RT.EEIAYGGGNIHCITQQQP
20 Y.TANGAIIFPLFDDP.....-KDKDAQELLEMLYPDRKIVGI-KA.REILLGGGNIHCITQHLP
21 L.ITNKGVIVPQYGDE.....-NDALALKQVQEMFPDREIVGV-NT.VEVVYGGGNIHCITQQQP
22 L.ISNQQIIFPLLDSR.....-TDGQANDLLQQMFPGYAIVGV-PA.REILLGGGNIHCITQQIP
23 L.ISNQQIIFPLLDSR.....-TDGQANDLLQQMFPGYAIVGV-PA.REILLGGGNIHCITQQIP
24 L.IVNGHVFLPMLDED.....-TDAIAIDILQNAMPEYQIIAI-PS.REVLLGGGNIHCITQQIP
25 L.ITNHRIVFPLLDPA.....-TDDIAAQKLQEIFPEHEIVGV-PA.REILLGGGNIHCITQQIP
26 Y.IANKAVLVPQFEDV.....-NDQVALDILSKCFPDRKVVGI-PA.RDILLGGGNIHCITQQIP
27 Y.IANKAVLVPQFEDV.....-NDQVALDILSKCFPDRKVVGI-PA.RDILLGGGNIHCITQQIP
28 Y.IANGGIVAPAFGDK.....-WDEEACAVLQKAFPDHEVI-----.------------------
29 Y.AGNSSIVVPLFGDR.....-NDQVALATLAELFPQHKIVGIENS.REILLGGGNVACITMP--
30 L.ITNDGVIVPQYGDE.....-NDHLALEQVQTMFPDKKIVGV-NT.VEVVYGGGNIHCITQQEP
31 Y.IANHAVIVPTFNHP.....-NDQRACAVLQQCFPDRRVVGI-EA.TDVIWGLGSWHCLSQQVP
32 Y.IANTVVLVPTYRCP.....-RDQQAIDILQQCFPKREVVGI-DC.SDLIWGLGAIHCVTHEEP
33 L.IVNGGIIAPSFDDP.....-LDHTG-------------------.------------------
34 L.VINGAVLVPVYDDP.....-ADEAALEAIGRAFPGREIVGI-DC.RPLIIQHGSLHCVTMQLP
35 L.VINGAVLVPTYGDP.....-GDDAALAAIGQAFPGREIIGI-DC.RPLILQHGSLHCVTMQLP
36 V.MPNGAIIFPTFGDE.....KYDALAHKKFEEIFPEREIVGFI--.------------------
37 Y.ISNNHVVVPTFRDK.....-NDEVALEILQQLFTDRKVTGL-DS.TDIIWGLGSFHCLSQQEP
38 Y.IGNGFVVVPQYGDP.....-NDKQALDVLRPLFPGREVIGV-PS.RKIIEGGGSFHCLTQQQP
39 L.VINGAVLVPTYNDP.....-ADEAAIAAIAAAFPDRLAIGI-NC.RPLLEQHGSLHCITMQLP
40 L.FVNGAVLLPIYGDE.....-KDQEAIRTMKRACPNHEIVPI-DC.RVLIRQHGSLHCVSMQ--
41 L.PINGAVIAPQFGDA.....SADRHCGELLGRLYPGRDIVQL-NI.DPIAAGGGGIHCVTKHMP
42 Y.VCNRAVIAPQFGDS.....RADRNTRDTLVDLFPGREVIQL-NI.DGIAAGGGGIHCTTQQQP
43 L.IIEGAVLMPTYNDP.....-ADTIAQSVLAEAFPTREIVPV-PC.RPLIWQNGSLHCITMQIP
44 L.PINGAVIAPQFGDA.....SADRHCGELLGRLYPGRDIVQL-NI.DPIAAGGGGIHCVTKHMP
45 Y.VCNGAVIALEFGDA.....RADRNARSALRELFPEREVVQL-NI.DAIAAGGGGIHCATQQQP
46 L.IIEGAVLMPTYDDP.....-ADTIAQSVLAEAFPTREIVPV-PC.RPLIWQNGSLHCITMQIP
47 L.IIEGAVLMPTYDDP.....-ADTIAQSVLAEAFPTREIVPV-PC.RPLIWQNGSLHCITMQIP
48 Y.VCNGGVVLCAFGDP.....-NDELAAGIFRRLFPERTVTLV-DA.RTIFAGGGGIHCITQQQP
49 L.IIEGAVLMPTYDDP.....-ADTIAQSVLAEAFPTREIVPV-PC.RPLIWQNGSLHCITMQIP
50 Y.LCNGGVVLCGFDDP.....-RDETAAGIFRRLFPERTVTLV-DA.RTIFSGGGGIHCITQQQP
51 Y.IANTTVVVPTYGVE.....-ADAKAVEAIAKLFPSRRTIGL-PA.RTILEGGGAFHCITQQ--
52 Y.IANRTVAVPTYGAP.....-QDAAAVSAIAALFPGRRTVGL-PA.RTILLGGGAFHCITQQQP
53 F.VINGAVIAPEFGDK.....DADKKAFDLLKKLYPNRDVVQI-NI.DAIAAGGGGIHCVTSHQP
54 L.IVNGAVLMPAYGDA.....-ADATAQAVLAQAFPHHEIVPV-PC.RALIWQNGSLHCLTMQLP
55 L.IMNDAILYPTYQQP.....DNDRKAGEVLQQAFPKHQVIGI-DC.RALIKQHGSLHCVTMQYP
56 L.LCNNALIVPTYNDP.....-KDALILETLKQHTP-LEVIGV-DC.NTLIKQHGSLHCVTMQ--
57 L.LCNNALIVPTYNDP.....-NDTLILETLRQHTP-LEVIGV-DC.NTLIKQHGSLHCVTMQ--
58 Y.IGNTVVLVPNYNDP.....-NDKIANDTIQKLYPDRKIVGI-DV.RELYKNGGMIHCVTQQQP
59 L.IVNGAVLMPAYGDA.....-ADAAAQAVLADAFPQHQIVPV-PC.RPLIWQNGSLHCLTMQLP
60 Y.IGNTVVLVPNYNDP.....-NDKIANDTIQKLYPDRKVVGI-DV.RELYKNGGMIHCVTQQQP
61 L.FVNGGLLVPTYGDK.....-NDKKALEILSLALPTRRVVGV-DC.RSLILWHGSLHCVSMQ--
62 Y.IGNTVVLVPNYNDP.....-NDKIANDTIQKLYPDRKVVGI-DV.RELYKNGGMIHCVTQQQP
63 L.IANEAVIVPIYAEE.....-SGAFAVEVIKGLFPERQVIGL-PS.TAILTGGGSFHCISQQEP
64 Y.IANGAIIMPAYGIE.....-ADHVAAQTLAEAFPGREVVPV-QI.NHLAHGGGGVHCITQQQP
65 Y.VANSVVVLCAFDDP.....-RDARARAVLAAAYPDRAVVPV-DA.RDVFAFGGGIHCITQQQP
66 L.IINGAVLVPTYDSH.....-LDAVALSVMQGLFPDREVIGI-DC.RPLVKQHGSLHCVTMQYP
67 Y.IGNEVVLVPIYGDE.....-HDKLGLQIIEGQFPGRRIIGI-YI.NELFAYGGMIHCVTQQ--
68 Y.IGNKVVVVPVYGAK.....-NDSAIVQAFEALFPSRKVVAL-PA.GHILTGGGSFHCISQQWP
69 LrLGMDRMLVPTFRST.....ASDQHALALLRELCPGVEVVGV-DC.FDIAWGLGALHCASCHEP
70 Y.IANGAIIMPAYGVA.....-ADDAAAATLARAFPAREVVPV-RI.DHLAHGGGGVHCITQQQP
71 I.LVNGAVIVSAFGVE.....-QDQAAREAFSRAFPGRNVEML-PI.PTLSIGGGSIHCSTQQQP
72 V.FINNALIVPFYKDK.....-NDEIIAKRLSKALPNHKIIGV-DA.RVFLRQNGSLHCSC----
73 V.ITSDLVVVPVFGSP.....-HDDDGVAAIAELFPDRATVGV-MG.DAVLAGGGGFHCASQQMP
74 V.IANDVVIVPRYWQPdr7yqQKDQAALAAFQSVFPNKKIVAI-NP.ENINAGGGGMHCIVQQQ-
75 L.ICNDVAFVPVYGVS.....-EDQIAVDVLTTAMPNKTIVTV-RC.EALLEQHGSLHCATMQI-
76 L.ISNEHIIYPLLDEK.....-HDKDVAMLLAKLYPNYEVTGV-NA.REILLGGGNIHCITQQIP
77 Y.ACNGAIVMPKFNDA.....AADAAAIAAIRPYAGNRAIVQV-DI.LGIASGGGGIHCSTREVP
78 L.ILNNRVFVPVNGPA.....SVDNDALNVYKTAMPGYEIIGVKGAsGTPWLGTDALHCRTHE--
79 L.ILNNRVFVPVNGPA.....SVDNDALNVYKTAMPGYEIIGVKGAsGTPWLGTDALHCRTHE--
80 L.ESCDALYVPKFGLA.....-KDEEVLRYIQQYT-EKQVIQI-HV.GEISTMGGAMNCLTWYCP
81 L.ETCDALYVPKFGLA.....-KDREVLPYIQQHT-EKQVIQI-HV.GEISTMGGAINCLTWYCP
82 L.ETCDALYVPKFGLA.....-KDREVLRYIQQHT-EKQVIQI-HV.GEISTMGGAMNCLTWYCP
83 -.--------------.....-------------------------.------------------
84 V.ILNGAVIVPTYNQP.....KNDAEALEQVQKAFPNYEIIGL-DA.RTVIRQHGSLHCLTMQYP
85 Y.IGNEVVLVPVYGDE.....-HDKLGLQIIEGQFPGRRIVGI-YV.NELYAYGGMIHCVTQQ--
380
|
1 AEPTSVAENH
2 AEPTSVAEN-
3 AEPTSVAEN-
4 A---------
5 AEPTSVAEN-
6 ----------
7 ----------
8 ----------
9 A---------
10 A---------
11 A---------
12 A---------
13 A---------
14 ----------
15 A---------
16 ----------
17 ----------
18 ----------
19 A---------
20 ----------
21 ----------
22 A---------
23 A---------
24 ----------
25 A---------
26 ----------
27 ----------
28 ----------
29 ----------
30 ----------
31 AG--------
32 A---------
33 ----------
34 ----------
35 K---------
36 ----------
37 ----------
38 AGR-------
39 A---------
40 ----------
41 ----------
42 ----------
43 A---------
44 ----------
45 ----------
46 A---------
47 A---------
48 ----------
49 A---------
50 ----------
51 ----------
52 ----------
53 ----------
54 A---------
55 ----------
56 ----------
57 ----------
58 ----------
59 A---------
60 ----------
61 ----------
62 ----------
63 ----------
64 AWP-------
65 ----------
66 ----------
67 ----------
68 ----------
69 AIARS-----
70 AW--------
71 ----------
72 ----------
73 ----------
74 ----------
75 ----------
76 ----------
77 ----------
78 ----------
79 ----------
80 S---------
81 S---------
82 S---------
83 ----------
84 ----------
85 ----------