Citations (SAM, SAM-T99, HMMs)
10 20 30 40
| | | |
1 ...SEESRE.SPA.EHG.YYMPAEWDSHAQTWIGWP..E.RQD.NW.....RH.N....ALP...
2 ...MEESRE.SPA.EHG.YYMPAEWDSHAQTWIGWP..E.RQD.NW.....RH.N....ALP...
3 ...MEESRE.SPA.EHG.YYMPAEWDSHAQTWIGWP..E.RQD.NW.....RH.N....ALP...
4 ...MTTLNS.TPR.ADG.FHMPAEWAPQTQVWMVWP..E.RPD.NW.....RL.G....GKP...
5 ...----RE.SPA.EHG.YYMPAEWDSHAQTWIGWP..E.RQD.NW.....RH.N....ALP...
6 ...MTTLKS.TPR.ADG.FYMPAEWAPQTQTWMIWP..E.RPD.NW.....RL.G....GKP...
7 ...MSNPTS.TPR.ADG.FRMPAEWEPHEQTWMVWP..E.RPD.NW.....RN.G....GKP...
8 ...MTTLNS.TPR.ADG.FHMPAEWAPQTQVWMVWP..E.RPD.NW.....RL.G....GKP...
9 ...MGQLKG.LPV.EDG.FRMPGEYEPHIGCFMIWP..E.RPD.NW.....RL.G....GKP...
10 ...MKTLQT.SPK.KDG.YRMPGEFEAHKDVYLLWP..E.RPD.NW.....RE.G....AKP...
11 ...MGQLKG.LPV.EDG.FRMPGEYEPHIGCFMIWP..E.RPD.NW.....RL.G....GKP...
12 ...MRTIDS.SSK.KDG.FRMPGEFEKHAGCYIIWP..E.RPD.NW.....RL.G....AKP...
13 ...MRTIDS.SSK.KDG.FRMPGEFEKHAGCYIIWP..E.RPD.NW.....RL.G....AKP...
14 ...MKTLNS.TPR.ADG.FHMPAEWAPQTQVWMVWP..E.RPD.NW.....RL.G....GKP...
15 ...MRTIDS.SSK.KDG.FRMPGEFEKHAGCYIIWP..E.RPD.NW.....RL.G....AKP...
16 ...MGQLKG.LPV.EDG.FRMPGEYEPHIGCFMIWP..E.RPD.NW.....RL.G....GKP...
17 ...MGQLKG.LPV.EDG.FRMPGEYEPHIGCFMIWP..E.RPD.NW.....RL.G....GKP...
18 pepMRTLSG.TPR.ADG.FRMPAEWEPHAQTWMLWP..E.RPD.NW.....RL.G....GKP...
19 m..SKKMNS.TPK.KDG.FWMPGEWEKHDQCWMIWP..E.RSD.NW.....RL.G....AKP...
20 ma.KRIKNT.TPK.QDG.FRMPGEFEKQKQIWMLWP..W.RND.NW.....RL.G....AKP...
21 ma.KRIIGT.TPK.EDG.FRMPGEFEAQDQIFMIWP..E.RPD.NW.....RD.G....AKP...
22 mlqQQALPG.TPR.QDG.FFMPAEWAPQDAVWMLWP..Y.RQD.NW.....RG.K....AIP...
23 mlqQQALPG.TPR.QDG.FFMPAEWAPQDAVWMLWP..Y.RQD.NW.....RG.K....AIP...
24 makATTMEG.RPA.KMG.FRMPAEWEPHEQCWMGWP..E.RRD.NW.....RE.L....AGP...
25 ...-MKLST.TPA.QDG.FYFPAEFQPVSEVWLAWP..E.RKD.NW.....RD.D....ALP...
26 ...------.---.---.--MPAEWAAQQAVWMIWP..Y.RPD.NW.....RA.A....GAY...
27 ...---MMD.SPK.KLG.YHMPAEYEPHHGTLMIWP..I.RPG.SW.....PF.Q....GKA...
28 ...---MMD.SPK.KLG.YHMPAEYEPHHGTLMIWP..T.RPG.SW.....PF.Q....GKA...
29 m..ARLLDT.TPK.QDG.FRLPGEFEAKAGCWLGWP..E.RTD.VW.....RN.G....AKP...
30 ...------.---.---.--------------MIWP..E.RPD.NW.....RD.G....GKP...
31 ...MTTLHS.TPR.ADG.FHMPAEWAPQTQTWMIWP..E.RPD.NW.....RL.G....GKP...
32 ...----MA.TPA.ELG.YRMPAEWEPHQATWLSWP..H.KEE.SW.....PG.I....IDR...
33 tarQPFKSE.TPLtTFP.FRFPAEWEPQSAILIAWP..H.ANT.DW.....SA.H....LAD...
34 tawQPFKNE.TPLtTFP.FRFPAEWEPQSAILIAWP..H.ANT.DW.....SA.H....LAD...
35 tawQPFKSE.TPLtTFP.FRFPAEWEPQSAILIAWP..H.ANT.DW.....SA.H....LAD...
36 tawQPFKSE.TPLtTFP.FRFPAEWEPQSAILIAWP..H.ANT.DW.....SA.H....LAD...
37 ...------.---.-MA.IRLPAEWEEQDGVLIAWP..H.PGS.DW.....YP.W....LRL...
38 ...------.---.-MI.TRLPAEWEEQDGVLLAWP..H.AES.DW.....LP.W....LPM...
39 ...------.-MS.EPT.YFMPPEWAPHASTWLSWP..H.KLE.SW.....PG.K....FEP...
40 ...-----M.TPK.QTG.FYMPGEFEQHKRTWMIFP..F.RND.NW.....RQ.E....AVP...
41 mkhFTPQDP.TPR.DLG.FAMPPEWAPHEATWMGYP..A.DDE.LW.....FG.H....LAG...
42 ...--MNKN.TPA.QQG.YSFPAEWAKHKATWLSWP..H.KEA.SW.....PG.K....LDS...
43 ...----MS.QGQ.QSD.RRFPAEWEAQDGVLIAWP..H.ADS.DW.....RS.L....LDQ...
44 qlnFGKNMT.VQV.EMRaPHLPAEWHLQSGIQLTWP..H.AGT.DW.....AY.M....LKE...
45 le.FGSPRG.QAAaADH.WHMPDEHLPQERVFLAYA..A.SPS.IW.....KD.L....AED...
46 le.FGSPRG.QAAaADH.WHMPDEHLPQERVFLAYA..A.SPS.IW.....KD.L....AED...
47 m..LGRAAH.AQQ.GAT.WHMPDEGAPHTATWMAFG..P.SED.IW.....GA.R....LLP...
48 ...------.---.-MT.FRMPPEWAPHERTWMAWP..G.PNA.TF.....TD.Aee..LAG...
49 ...------.--M.TDR.LRFPAEWEPQSAVLVAWP..H.AGT.DW.....AE.R....LAD...
50 ...--MQHN.KNN.NSG.WMMPAEWVTHAATWMVWP..H.NQA.LW.....ES.GwgvtLPL...
51 ...------.---.--M.RRMPAEWERQSAVLMAMP..H.EES.DW.....YP.Y....LEE...
52 ...----MS.TPA.ADG.FRMPAEWTPHERTWMAWP..G.PNP.TFdh...PD.D....LAE...
53 ...------.---.---.--MPDEGAPHAATWMAFG..P.SLS.VW.....GArL....LPE...
54 ...------.---.--M.KRMLAEFEKIQAILMAFP..H.EFS.DW.....AY.C....IKE...
55 ...------.---.--M.KRMLAEFEKIQAILMAFP..H.EFG.DW.....AY.C....IEE...
56 ...----MQ.TPL.SDG.FIQPAEWQPHSACWLAWP..S.DAE.LW.....QS.D....LPK...
57 ...------.-MK.KIK.YRLKAEWEEQIAILMAFP..H.KNS.DW.....AI.H....IEV...
58 ...-----M.TGM.TDS.VRFPAEWESQSAILIAWP..H.AGT.DW.....AE.R....LAE...
59 ...------.--M.TKR.LFLP-EWAPQEAVQLTWP..H.DRT.DW.....AY.M....LDE...
60 ...------.---.MSL.FFRPAEWLPHRACWLAFP..S.HED.LW.....GE.L....LPQ...
61 lglSPARVL.AAS.EGR.WFMPDEGDKHERAYMAFG..A.QDA.IW.....ED.F....TED...
62 kgkGNEKVE.VQK.TFGkYTMPDEKDKHEGTWLQWP..H.EYT.YG.....EE.Y....KQE...
63 kgkEGEKVE.IQK.TVGkYTMPDEKDKHEGTWLQWP..H.EYT.YG.....EE.Y....KQE...
64 ...------.---.---.--MPDEKDKHEGTWLQWP..H.EYT.YG.....EE.Y....KKE...
65 lrfSLTAFH.WAC.RMT.VTVPAEWAPHRAMWVGFP..S.HAE.LW.....QE.D....LEQ...
66 ...------.---.-PT.QRMPAEWEPHQRTWMAFP..T.PNP.TF.....GE.A....GGPdlt
67 vpdSLSSAG.ASS.FRS.YRFPAEWEPCEAVWLAWP..H.NRD.TW.....PG.H....FEP...
68 ...------.---.---.--------------MLW-..-.-ES.EW.....GV.S....LAD...
69 ...------.---.NSL.FYMPAEWEKHEGTWLQWP..H.DRThRG.....EG.Y....RAK...
70 ...------.---.---.---------MDATWLGWPvlHdRED.LW.....GS.H....YAQ...
71 ...------.---.---.IKSIPEWSEQEYLMLSLP..H.EKS.DW.....NP.Y....LEE...
72 ...------.---.-MP.YHQPAEWMPHDAVWIGFP..S.DAS.LW.....LE.D....LEP...
73 et.SPAYRQaLNQ.AKT.FRMPAEFEPITSIWMAYP..T.YEN.--.....-Q.A....GYP...
74 qpdFPDTGQ.PHM.TSQ.FRMPPEWHPQDWLWIGFP..H.LAE.EW.....SG.V....IDE...
75 ...------.---.---.------------------..-.---.--.....--.-....---...
76 ...------.---.-MN.SALKPEWSAVRAIVIAWP..Y.EDS.DW.....QD.N....YAQ...
77 pgtTPGTKP.STR.PVT.YRLPAEDAPHASTYMAFA..S.GADgIWlp8stDA.G....IDR...
78 emqRAFQET.NPP.AGP.VRAIAEYERSAAVLVRYP..F.G--.--.....--.-....---...
79 emqRAFQET.NPP.AGP.VRAIAEYERSAAVLVRYP..F.G--.--.....--.-....---...
80 ...------.---.---.------------------..-.KGI.IF.....TA.I....PDE...
81 ...------.---.---.------------------..-.KGI.IF.....TA.I....PDE...
82 ...------.---.---.-----------------EqkH.NGI.IF.....TA.I....PNE...
83 ki.EMDLEG.KPS.LMG.YRMPAEWEPHQQCWMGWP..E.RPD.NW.....RE.N....ARF...
84 ...------.---.---.------------------..-.---.--.....--.-....---...
85 ...------.---.---.------------------..-.---.--.....--.-....---...
86 ...MKIVGT.TPK.EDQ.YYLPAETKRHRESIMMWP..E.RSD.NW.....RN.G....AKP...
50 60 70
| | |
1 .A.QRVFADVAKAIS.....K.F..EPV.TVCA.SP.AQ...W.E.N.ARK....QL.P..E...
2 .A.QRVFAGVAKAIS.....K.F..EPV.TVCA.SP.AQ...W.E.N.ARK....QL.P..E...
3 .A.QRVFADVAKAIS.....K.F..EPV.TVCA.SP.AQ...W.E.N.ARK....QL.P..E...
4 .A.QAAHVAIAKAIA.....R.F..EPV.TVAV.SA.AQ...Y.D.N.ARA....RLdM..P...
5 .A.QRVFADVAKAIS.....K.F..ELV.TVCA.SP.AQ...W.E.N.ARK....QL.P..E...
6 .A.QAAHAAVAKAIA.....R.F..EPV.TVAV.SA.GQ...Y.E.N.ARA....RLdV..P...
7 .A.QAAFAAVAKAIA.....R.F..EPV.TVCA.SA.GQ...Y.E.N.ARA....RL.D..Dg..
8 .A.QAAHVAIAKAIA.....R.F..EPV.TVAV.SA.AQ...Y.D.N.ARA....RLdM..P...
9 .A.QQNYKEVAVAIS.....N.F..EPV.TMFV.SP.NQ...Y.K.N.ARK....EL.P..D...
10 .A.QATFAKVAETIA.....Q.F..ESV.TVGV.SD.RQ...Y.T.N.ARH....ML.A..D...
11 .A.QQNYKEVAVAIS.....N.F..EPV.TMFV.SP.NQ...Y.K.N.ARK....EL.P..D...
12 .A.QKAFVDVATAIS.....R.F..EPV.TVVA.SS.SQ...Y.V.N.ARY....ML.P..D...
13 .A.QKAFVDVATAIS.....H.F..EPV.TVVA.SS.SQ...Y.V.N.ARY....ML.P..D...
14 .A.QAAHVTLAKAIA.....R.F..EPV.TVAV.SA.GQ...Y.E.N.ARR....QLdQ..P...
15 .A.QKAFVDVATAIS.....H.F..EPV.TVVA.SS.SQ...Y.V.N.ARY....ML.S..D...
16 .A.QQNYKEVAVAIS.....N.F..EPV.TMFV.SP.NQ...Y.K.N.ARK....EL.P..D...
17 .A.QQNYKEVAVAIS.....N.F..EPV.TMFV.SP.NQ...Y.K.N.ARK....EL.P..D...
18 .A.QAAFATVARAIA.....R.F..EPV.TVGV.SA.AQ...Y.E.N.ACV....RL.A..Ga..
19 .A.QRVFVNVANAIA.....K.Y..EKV.TMLV.SH.QQ...F.E.N.ARN....LL.D..Q...
20 .A.QKAFLEVAEAIS.....E.F..EPV.SLCV.PP.LQ...Y.E.N.ALA....RV.S..Elgs
21 .V.QIAFTNVAKAIS.....R.F..TPV.TMLV.SQ.SQ...Y.Q.N.ARY....QL.P..A...
22 .A.QQTFAKVAEAIS.....R.A..TPV.FMGV.PA.EF...M.A.Q.AKA....TM.P..A...
23 .A.QQTFAKVAEAIS.....R.A..TPV.FMGV.PA.EF...M.A.Q.AKA....TM.P..A...
24 .A.RKVFARTAIAIS.....K.F..ESV.TICA.SA.KQ...Y.P.Y.VHE....LM.LhqP...
25 .A.QETFARIANLIA.....E.V..TKV.CVAV.CS.HN...F.D.R.ARQ....ML.H..S...
26 .A.QATFAKVVDAIG.....A.A..TPV.YMGV.PK.AF...L.A.K.AKT....VM.P..S...
27 .A.KRAFTQIIETIA.....E.G..ERV.YLLV.EQ.AY...L.S.E.AQS....YL.G..D...
28 .A.KRAFTQIIETIA.....E.G..ERV.YLLV.EQ.AY...L.S.E.AQS....YL.G..D...
29 .A.QKVWVQIVTAIS.....Q.S..EPV.TVCA.SA.SQ...F.A.T.ARR....QL.P..P...
30 .V.QEAFTNVAKAIS.....Q.F..TPM.NVVV.SQ.QQ...F.Q.N.CRR....QL.P..P...
31 .A.QAAHVAVAKAIA.....R.F..EPV.TVAV.SA.GQ...Y.E.N.ARA....RLdV..P...
32 .I.WPVYARFVAELA.....R.G..ETV.HINV.ND.AA...MaD.Q.ARF....FL.A..Eaga
33 .V.EETYIALVAAIT.....R.F..QMV.IICV.LD.DDlqtY.T.E.ARL....RS.A..Svam
34 .V.EETYITLVAAIT.....R.F..QMV.IICV.LD.DDlqtY.T.E.ARL....RS.A..Svam
35 .V.EETYIALVAAIT.....R.F..QMV.IICV.LD.DDlqtY.T.E.ARL....RS.A..Svam
36 .V.EETYIALVAAIT.....R.F..QMV.IICV.LD.DDlqtY.T.E.ARL....RS.A..Svam
37 .V.EPVFAQIVREIT.....R.F..ETA.LVVA.AD.GE...R.T.A.ALL....EA.V..Garm
38 .V.ELVFAQIVKEIA.....H.F..EAV.LLVA.AE.GE...R.T.S.AILsaagAS.M..E...
39 .V.PAVFAELAYQLS.....R.S..ETV.NINV.LD.DA...M.EaQ.ARE....LL.K..Erd9
40 .A.QKTITNLARKIS.....E.F..EEV.IMIV.SR.DH...L.N.K.AMD....LL.H..Ds..
41 .V.RDEYAGLVRTIA.....R.F..ERV.ELLV.RD.EE...S.E.RdARA....RL.T..Gh..
42 .I.FPQYAQFIKLIA.....E.G..EEV.RINV.AN.AA...M.E.A.FAR....GY.I..Eka7
43 .V.DRVYRDLAEAVT.....R.F..EQL.LIVT.PE.P-...-.D.R.VAE....QL.A..Qtt6
44 .V.QECFVNIAREIA.....K.R..ELL.LIVT.PE.PEev.K.K.Q.IVA....TVnM..D...
45 .V.NRSVALLARTIA.....R.Y..QPV.TLLC.RP.TQ...E.A.A.ARR....AC.G..Ga..
46 .V.NRSVALLARTIA.....R.Y..QPV.TLLC.RP.TQ...E.A.A.ARR....AC.G..Ga..
47 .VaRANLAAIAKAIA.....A.H..EPL.KMLV.RE.QD...Y.A.I.ASR....LC.G..S...
48 .A.RAAWASVARAVR.....R.F..EPV.TMVH.GP.GQ...A.A.T.ARE....LL.G..P...
49 .V.EETYIALVTAIS.....R.F..EPV.VICV.AD.DDlqiY.A.E.ARL....RS.A..Rvdm
50 .V.QEDFARVANAIA.....R.F..EPV.KMVV.DP.SA...I.A.S.AKA....LC.G..P...
51 .A.RENFIQIIEEIT.....K.R..ERC.LLLV.DD.WK...L.Y.E.ERL....GH.L..S...
52 .S.CRAWADVARAIR.....R.F..EPV.TVVC.GP.GR...S.A.E.ARD....LL.G..P...
53 .V.RRDLARVASAIA.....A.F..EPV.RMLA.RE.NE...L.D.L.AGR....LC.G..S...
54 .A.RESFLNIIQTIA.....K.H..AKV.LVCV.HT.ND...I.I.G.YET....LKnL..P...
55 .A.RESFLHIIQTIA.....K.H..AKV.LVCV.HT.ND...T.I.G.YET....LKnL..P...
56 .A.QVEFAGLCRTIAdp9lpR.G..EYL.KILV.PD.AE...A.E.R.AAR....LA.L..E...
57 .A.RECFVRIIEQIL.....Y.F..ESV.ILCV.DI.ND...D.E.G.MAL....LH.T..Hf20
58 .V.EDTYIALVTAIT.....R.F..QPV.IICV.AD.DDlqiY.A.E.ARL....RS.A..Rvem
59 .V.ETCFVRIATAIL.....R.H..ERL.IVVC.PD.R-...-.K.R.VFG....LL.P..Pelh
60 .V.RFEFAALCRAIA.....D.P..DPV.TGQC.RG.EQ...L.K.I.LVL....DE.T..Gk11
61 .V.QEALGRIARAIA.....R.Y..EPL.TIYC.RS.GE...R.S.L.AEE....IC.Gs.S...
62 .V.EPIWVKIASALT.....E.G..EKV.HIVA.YDeEE...K.E.R.INK....LL.I..Dkg6
63 .V.EPIWVKMASALT.....E.G..EKV.HIVA.YDeEE...K.E.R.INK....LL.I..Dkg6
64 .V.EPIWVKMASALT.....E.G..EKV.HIVA.YDqEE...K.E.R.INN....LL.T..Deg6
65 .A.QQEVADLARALA.....G.PgaERVrLMVV.GD.EA...E.A.A.ARA....LL.S..D...
66 rA.RAAWSTVANTVA.....R.Y..EPV.TVLV.SP.AD...R.T.A.ARE....AL.D..P...
67 .V.PAAFAQFVRAIH.....E.S..TPV.RILA.TG.LV...A.E.D.CRK....HL.Q..Qig7
68 .V.QQDFAAVANAIA.....R.F..EPV.KLVV.DP.AA...L.D.R.AGE....LC.A..G...
69 .L.DDIWVTMVKELH.....Y.G..ETV.HIVV.YD.EK...E.KvH.VQS....KL.T..Eak6
70 .V.CREFALVARTIA.....R.Y..QRC.VVAA.HH.SQ...A.D.A.ARE....LV.G..A...
71 .I.LQSYKEFVKVVS.....E.F..QKV.LLIA.PKqSD...F.E.N.FKD....I-.-..K...
72 .A.QAEVVAFAKAVAaqg..E.G..EKV.YLVAaHK.EA...A.D.Q.AVK....MA.G..S...
73 .S.QTVQKAMVKAIA.....P.T..VKI.DFLL.NE.PE...E.K.V.IIN....GW.L..Kta7
74 .A.QVQIAAFANAVA.....DsG..QEV.RLVV.RD.AA...N.EmR.AKS....LV.S..G...
75 .-.------------.....-.-..---.----.--.--...-.-.-.---....--.-..-...
76 .A.EQCYWAMLIAFS.....T.Y..SDV.WVLL.HS.SI...S.K.A.QWL....ED.L..Dk13
77 .V.RADLMDVAKAIG.....A.T..EPV.DMLV.LP.AD...L.D.A.ARA....LL.A..Ta20
78 .-.--IPMELIKELA.....K.N..DKViTIVA.SE.SQ...K.N.T.VIT....QY.T..Qsg6
79 .-.--IPMELIKELA.....K.N..DKViTIVA.SE.SQ...K.N.T.VIT....QY.T..Qsg6
80 .A.NEYYEPFYEELI.....Y.F..NE-.NLNE.KK.GA...T.D.Q.FIS....LS.V..E...
81 .S.NEYYEPFYEEII.....Y.F..NE-.NLNK.KK.GA...T.D.Q.FIS....LS.V..E...
82 .S.NEYYQPFYEDLI.....Y.F..NEC.-LNE.KK.SI...A.D.Q.LIS....LS.V..E...
83 .G.QHAFVEVASAIS.....Q.F..EPV.TICV.SS.AQ...Y.T.T.ACH....LL.QnkP...
84 .-.------------.....-.-..---.----.--.--...-.-.-.---....--.-..-...
85 .-.------------.....-.-..---.----.--.--...-.-.-.---....--.-..-...
86 .A.QKTFAEIAAIIN.....R.Y..EPV.TMLV.SK.EQ...Y.Q.N.ARH....AL.P..A...
80 90 100 110 120 1
| | | | |
1 ..D.I..RVV..E.M..SMNDSWFRDSGPTFIVRKRPVKLSSLNRNIAGIDWNFNAWGG.....A
2 ..D.I..RVV..E.M..SMNDSWFRDSGPTFIVRKRPVKLSSLNRNIAGIDWNFNAWGG.....A
3 ..D.I..RVV..E.M..SMNDSWFRDSGPTFIVRKRPVKLSSLNRNIAGIDWNFNAWGG.....A
4 ..N.I..RVV..E.M..SSNDAWVRDSGPTFVINDRG--------ELRGVNWEFNAWGG.....F
5 ..D.I..RVV..E.M..SMNDSWFRDSGPTFIVRKRPVKLSSLNRNIAGIDWNFNAWVG.....A
6 ..N.I..RVV..E.M..SSDDAWVRDSGPTFVINNSG--------EVRGVNWDFNAWGG.....F
7 ..N.I..RVV..E.I..SSDDAWVRDTGPTFVIDDKG--------DVRGVDWGFNAWGG.....F
8 ..N.I..RVV..E.M..SSNDAWVRDSGPTFVINDRG--------EVRGVNWEFNAWGG.....F
9 ..T.I..RVI..E.M..SNDDAWIRDYGPSFLVNDKG--------EMRGVDWGFNAWGG.....L
10 ..N.I..QVV..E.M..SNNDSWIRDCGPTFVVNDKG--------DSRGVDWTFNAWGG.....L
11 ..T.I..RVI..E.M..SNDDAWIRDYGPSFLVNDKG--------EMRGVDWGFNAWGG.....L
12 ..E.I..RVV..E.M..DNDDAWVRDSGPTFVVNDSG--------DVRGVDWSFNSWGG.....L
13 ..E.I..RVV..E.M..DNDDAWVRDSGPTFVVNDSG--------DVRGVDWSFNSWGG.....L
14 ..N.I..RVV..E.I..SNDDAWVRDTGPTFVINDHG--------EVRGVDWGFNAWGG.....F
15 ..E.I..RVV..E.M..DNDDAWVRDSGPTFVVNDSG--------DVRGVDWSFNSWGG.....L
16 ..T.I..RVI..E.M..SNDDAWIRDYGPSFLVDDKG--------DMRGVDWGFNAWGG.....L
17 ..T.I..RVI..E.M..SNDDAWIRDYGPSFLVDDKG--------DMRGVDWGFNAWGG.....L
18 ..D.I..RVV..E.L..SSDDAWVRDTGPTFLVDDAG--------EVRGVDWTFNAWGG.....F
19 ..N.V..RVI..E.M..SNDDSWMRDVGPTIVKNKDG--------EIRGVDWVFNAWEG.....F
20 h.N.I..RII..E.M..TNDDAWIRDCGPTFLVNDKG--------DLRAVDWEFNAWGG.....L
21 ..D.V..RVL..E.V..SNNDSWVRDCGPSFVINDKG--------ELRANDWTFNAWGG.....L
22 ..N.V..TLV..E.M..ASDDAWMRDTGPTMVINGAA--------ERRAVDWQFNAWGG.....L
23 ..N.V..TLV..E.M..ASDDAWMRDTGPTMVINGAA--------ERRAVDWQFNAWGG.....L
24 ..N.I..RVV..E.M..SMNDCWFRDIGPTFIVRKGAPGLGITEKNIAGIDWEFNAWGG.....A
25 ..D.V..RLV..E.I..PFNDAWMRDIGPTVLVNQAG--------ERRGISWQFNAWGG.....E
26 ..H.V..TLV..E.M..DSNDCWARDTGPTVVVNAEG--------ECRGVDWGFNAWGG.....H
27 ..K.V..VYL..D.I..PTNDAWARDTGPTILVNDKG--------KKLAVDWAFNAWGG.....T
28 ..K.V..VYL..D.I..PTNDAWARDTGPTILVNDKG--------KKLAVDWAFNAWGG.....T
29 ..Q.V..RVV..E.M..TCNDTWFRDSGPCFVVNDQSG-------EVRGVDFEFNAYGG.....L
30 ..E.I..TVY..E.M..SNNDAWVRDCGPSFVINDHG--------EIRGVDWTFNAWGG.....L
31 ..N.I..RLV..E.M..SSDDAWVRDTGPTFVINDSG--------EVRGVNWDFNAWGG.....F
32 vgD.I..RLH..E.F..PTNDAWCRDHGAIFVVRDTPAGR-----ELAATDWEFNAWGG.....K
33 q.Q.V..RFT..V.A..SYNDTWLRDSGPITLIGTNG--------DFRLLDFRFTGWGG.....K
34 q.Q.V..RFT..V.A..SYNDTWLRDSGPIILIGING--------DFRLLDFRFTGWGG.....K
35 q.Q.V..RFT..V.A..SYNDTWLRDSGPITLIGING--------DFRLLDFRFTGWGG.....K
36 q.Q.V..RFT..V.A..SYNDTWLRDSGPITLIGTNR--------DFRLLDFRFTGWGG.....K
37 e.R.V..AIV..E.L..PTNDTWARDFGPVTVERDG---------RPVLLDFGFNGWGL.....K
38 ..R.V..RIV..E.I..PTNDTWARDFGPLTVERDG---------NPVLLDFGFNGWGL.....K
39 aeR.I..VFH..R.I..PTNDAWCRDHGPNYVIRTQD-----GRRDKVIMNWEYNAWGG.....K
40 ..G.V..KMV..T.A..DSDDCWARDTGATFITNGK---------NVKAISWDFNSWGG.....N
41 ..N.V..RFH..R.V..PLDDSWLRDSGPLFVTRGEK------DPEVALVNWRFNAWGG.....K
42 mhN.V..FFH..H.F..PTNDAWCRDHGPAFLVNPAA------EQKKVIVDWGYNAWGG.....K
43 cdR.I..QIV..E.L..PTNDTWSRDFGPLTVETPAG---------LRLLDWGFNGWGL.....K
44 ..N.V..RFL..R.C..ETNDTWARDHGAITMIDTG---------NPSLLDFTFNGWGL.....K
45 ..N.I..DYL..A.L..PLDDIWVRDYGGCFVLNGEG--------EAGLVDFNFNGWGG.....K
46 ..N.I..DYL..A.L..PLDDIWVRDYGGCFVLNGEG--------EAGLVDFNFNGWGG.....K
47 ..S.V..ELV..Q.H..PVDDLWMRDTGPVFVKNASG--------QLGGVSFNFNGWGN.....K
48 ..D.V..DLV..E.R..ELDDAWMRDIGPTFVTDGRG--------GLAAVDWVFNGWGA.....Q
49 t.R.V..RFV..I.A..AYNDTWLRDSGPITLRQEAG---------FRLMDFRFTGWGG.....K
50 ..N.I..ELI..P.L..AVNDSWCRDSGPSFVVHPEQ--------GLAGVSWRFNAWGG.....K
51 ..N.L..IPL..E.L..LTNDTWARDFGPIGIEENG---------KKRLLDFGFNGWGL.....K
52 ..G.I..DTV..E.R..DLDDAWMRDIGPTFLTDGKG--------GLAAVDWTFNGWGA.....Q
53 ..G.V..ELV..A.Q..PLDDLWIRDSGPVFVKTGAG--------GMAAVDFNFNGWGG.....K
54 ..G.V..EIA..R.I..DTNDTWARDFGAISVENHG---------VLECLDFGFNGWGL.....K
55 ..G.V..EIA..R.I..DTNDTWARDFGAISVENHG---------VLECLDFGFNGWGL.....K
56 ..G.LgaRFH..R.I..RFGDIWLRDTAPIFLTGPCR--------ALAAVRFAFNGWGG.....K
57 qyG.L..HIV..R.V..PTNDTWARDFGGISVEAEGG---------IALFDFVFNGWGL.....K
58 a.Q.V..RFV..V.A..AYNDTWLRDSGPITLRHGDG---------FRLMDFRFTGWGG.....K
59 h.R.L..YCF..E.L..PSNDTWARDHGGISLLADG---------RPMIADFAFNGWGM.....K
60 dlN.P..QFY..Q.L..TFGDIWLRDTAPVGLINEAG--------ERRLLCLPFNGWGK.....K
61 ..N.I..TYQ..I.A..NLDDIWMRDISANFVIDDKN--------GLGAVDFNFSGWGN.....K
62 mdK.I..DFF..I.A..PTDDVWARDSGPIFVYDNNK--------NLKILDPAFNGWGK.....K
63 mdK.I..DFF..I.A..PTDDVWARDSGPIFVYDNNK--------NLKILDPAFNGWGK.....K
64 meK.I..DFF..I.A..PTDDVWARDSGPIFVYDSNK--------NLKILDPAFNGWGK.....K
65 ..TtV..EIV..R.G..QFGDIWLRDTGPIFV-DDAG--------KAVAAGFKFNGWGG.....K
66 ..R.I..EVV..E.V..PLDDAWLRDSGPTFVRGAQG---------PVAVDWTFNGWGA.....Q
67 sdS.L..RIV..D.V..PTNDCWIRDYGPTFVFGPDS--------EKIAVDWRFNAWGG.....K
68 ..N.V..ELI..E.L..AIDDSWCRDSGPSFVCHPQL--------GLAGVSWRFNAWGG.....K
69 mdK.I..DFL..I.E..ETDDVWIRDNGPIFVKDKKG--------NLCLTHWIFNGWGE.....K
70 ..S.V..DVV..P.V..AAEDNWLRDCGPIFLVSEQH--------GLGAAVFRFNCWGE.....K
71 ..N.V..EFF..K.C..DTNDTWIRDFGAIDIVENG---------RLKALDFTFNAWGN.....K
72 ..D.I..EVI..C.H..PFGDIWLRDNAPLFVKEGDK--------KALAL-FRFNGWGG.....K
73 asQ.V..RYH..L.V..PHEDLWIRDMGPIFAVNAD---------QTQVVDFGFNAW-S.....Y
74 ..A.V..TLE..R.R..TYGDVWLRDTGPLVVLDGAG------RREARL--FGFNGWGE.....K
75 ..-.-..---..-.-..------------------------------------LMLWGR.....L
76 rcA.V..SVI..DsI..DYDDTWIRDYGPLTTHSD-------------YVSFCFNGWGG.....K
77 agG.I..NLV..P.LadGFNDFWVRDTGCLFVRDTTN------DNALNAVGFNFNGWGNa25rsK
78 lsN.C..DFI..I.A..KTDSYWTRDYAGWFAMYDTN--------KVGLVDFIYN----.....-
79 lsN.C..DFI..I.A..KTDSYWTRDYTGWFAMYDTN--------KVGLVDFIYN----.....-
80 ..E.Q..DFHtsF.F..EYDDIWLRDVAPV-VTNH-------------LVKFKYQP--N.....Y
81 ..E.Q..DFYtsF.F..EYDDIWLRDVAPV-VTNH-------------LVKFKYRP--N.....Y
82 ..E.Q..DFHtsC.F..EYDDIWLRDVAPV-VTNH-------------LVKFKYRP--N.....Y
83 ..N.I..RIV..E.M..SMNDSWFRDSGPTFVVLDRESSSGYEVHPVAGIDWIFNSWGG.....T
84 ..-.-..---..-.-..------------------------------------------.....-
85 ..-.-..---..-.-..------------------------------------------.....-
86 ..E.I..RVI..E.M..SYNDAWIK----------------------------------.....-
30 140 150 160 170 180
| | | | | |
1 NDGCYNDWSHDLLVSRKI..LA.....LERIPR.F.Q.H.S.MILEGGSIHVDGEGTCLVTEECL
2 NDGCYNDWSHDLLVSRKI..LA.....LERIPR.F.Q.H.S.MILEGGSIHVDGEGTCLVTEECL
3 NDGCYNDWSHDLLVSRKI..LA.....LERIPR.F.Q.H.S.MILEGGSIHVDGEGTCLVTEECL
4 DGGLYAPWNLDSQVGSKV..LE.....IERCPR.Y.A.TqG.FVLEGGSIHVDGEGTLITTEECL
5 NDGCYNDWSHDLLVSRKI..LA.....LERIPR.F.Q.H.S.MILEGGSIHVDGEGTCLVTEECL
6 DGGLYSPWNRDSQVGGKI..LE.....IERSPR.Y.R.TeG.FVLEGGSIHVDGEGTLITTEECL
7 EGGLYFPWQRDDQVARKI..LE.....IERRAR.Y.R.T.DdFVLEGGSIHVDGEGTLITTEECL
8 DGGLYAPWNLDSQLGGKV..LE.....IERCPR.YvT.E.G.FVLEGGSIHVDGEGTLITTEECL
9 LDGLYFPWDKDNQIAKKV..CD.....IERLDY.Y.SqK.D.FILEGCSIHVDGEGTLVTTEECL
10 VDGLYFPWDKDDRVAQKV..CE.....IEGRDR.Y.R.L.DdLVLEGGSTHVDGEGTLLVTEECL
11 LDGLYFPWDKDNQIAKKV..CD.....LERLDY.Y.SqK.D.FILEGCSIHVDGEGTLVTTEECL
12 VDGLYFPWDKDDQVAQKI..CE.....LERKDR.Y.R.LaD.FVLEGGSIHVDGEGTLVTTEECL
13 VDGLYFPWDKDDQVAQKI..CE.....LERKDR.Y.R.LaD.FVLEGGSIHVDGEGTLVTTEECL
14 DGGLYAPWNRDEELAAKV..LE.....MERCQR.Y.Q.TeG.FVLEGGSIHVDGEGTVITTEECL
15 VDGLYFPWDKDDQVAQKI..CE.....LERKDR.Y.R.LaD.FVLEGGSIHVDGEGTLVTTEECL
16 LDGLYFPWDKDNQIAKKV..CE.....LERIDY.Y.SqK.D.FILEGCSIHVDGEGTLVTTEECL
17 LDGLYFPWDKDNQIAKKV..CE.....LERIDY.Y.SqK.D.FILEGCSIHVDGEGTLVTTEECL
18 AGGLYAPWNRDDQVARKI..LG.....IERCAR.Y.R.TeG.FVLEGGAIHVDGEGTLLTTEECL
19 KGGLYFPWDKDDAIARKV..CE.....ICNIDY.Y.R.T.D.FVLEGGSIHTDGDGTLYTTEECL
20 VDGLYFPWDQDALVARKV..CE.....IEGVDS.Y.K.TkD.FVLEGGSIHVDGEGTVLVTEMCL
21 VDGLYFPWDQDDLVAQKV..CE.....LERVDS.Y.R.T.DdFVLEGGSFHVDGQGTVLTTEMCL
22 NGGLYADWQQDEKVAVQV..SD.....FLKNAH.Y.S.A.P.LILEGGSIHTDGEGTLLTTAECL
23 NGGLYADWQQDEKVAVQV..SD.....FLKNAH.Y.S.A.P.LILEGGSIHTDGEGTLLTTAECL
24 TDGCYVDWSLDSYVAKKI..VE.....IERIPR.F.P.H.T.MVLEGGSIHVDGEGTCITTEECL
25 YNGLYDNWQQDDLVAGSV..CD.....IIGIDY.Y.R.A.P.FVLEGGAIHTDGEGTLYTTEECL
26 NGGLYFPWDKDEQVAQQM..LA.....QHGFAR.Y.R.A.P.LILEGGSIHVDGEGTCMTSAECL
27 YDGLYQDYEEDDQVASRF..AE.....ALERPV.Y.DaK.P.FVLEGGAIHSDGQGTILVTESCL
28 YDGLYQDYEEDDQVASRF..AE.....ALERPV.Y.DaK.P.FVLEGGAIHSDGQGTILVTESCL
29 DGGLYYPWDKDDQIASKI..LE.....IERFDR.Y.R.A.P.LIAELGGIQSDGQGSILTTEQCL
30 VDGLYFPWDQDDLVAQKI..CE.....IEHVDS.Y.R.T.DdFVLEGGSFHVDGQGTVLTTEMCL
31 DGGLYAPWNRDSQVGGKI..LE.....IERAPR.Y.R.TqG.FVLEGGSIHVDGEGTLITTEECL
32 ----YPPYDLDNQIPARM..AA.....YLGVPR.F.C.G.G.MVLEGGSIDVDGNGLLLTSEQCL
33 FEAKADDQLVSALHAKGL..FK.....--NTQM.H.S.I.N.FALEGGAIETDGAGTLLTTWRCL
34 FEAKADDQLVSSLHANGL..FK.....--NTQM.H.S.I.N.FALEGGAIETDGAGTLLTTWRCL
35 FEAKADDQLVSALHANGL..FK.....--NTQM.H.S.I.N.FALEGGAIETDGAGTLLTTWRCL
36 FEAKADDQLVSVLHANGL..FK.....--NTQM.H.S.I.N.FALEGGAIETDGAGTLLTTWRCL
37 FAADRDNLVTRRLRHLGI..FG.....DIPAEM.V.-.-.G.LVLEGGSIESDGRGTVLTTAECL
38 FAADRDNLITGRLHRTGA..FG.....--NAAL.E.T.V.G.LILEGGSIESDGNGTILTTAECL
39 ----YEPYDDDNAVPERV..AK.....AQGLPM.V.S.T.G.MVLEGGAIDVNGAGLLLTTTACL
40 FDGLYTTWKNDQKIAEYM..AR.....ISNIPI.I.K.T.PgFVLEGGSIHVDGEGTLITTKECL
41 -----FEWENDNRVPEYV..AQ.....FLGMGH.W.D.R.P.EVLEGGGLEIAGDGAALTTRSCF
42 ----YPPYDLDDVIPTKI..AQ.....MYNIPV.F.H.P.G.IVMEGGSVEFNGRGTLLTSTSCL
43 FAANHDNQVTRRLWQQGI..FG.....TTPLET.V.-.-.P.LIFEGGSIESDGRGTLLTTSQCL
44 FASELDNLITGQAVKAGA..LK.....GQYIDC.L.-.-.D.FVLEGGSIESDGMGTLLTTTECL
45 -----QQAGNDSRVAGVL..SE.....RLEVRY.I.A.S.Q.LTGEGGGIEVDGRGTAILTESCW
46 -----QQAGNDSRVAGVL..SE.....RLEVRY.I.A.S.Q.LTGEGGGIEVDGRGTAILTESCW
47 -----QEHDQDAEVAPFV..AE.....RAGARL.L.D.T.R.LVLEGGGIEVDGEGTAIITRSCV
48 ---DWARWEHDAEIARHV..AD.....LAAAPV.L.S.S.P.LVNEGGAIHVDGEGTVLLTDTVQ
49 FEASLDDQLVSSLDAAQV..--.....FVPAQV.E.T.V.D.FALEGGAIETDGAGTLLTTWKCL
50 -----SAHDLDESLARRV..LN.....HLGGEC.F.G.T.A.LSNEGGAIHVDGEGTLITTESVL
51 FASFLDNQANRALARKGI..YQ.....---VPL.E.T.K.N.LILEGGSIESNGAGLILTNTQCL
52 ---SWARWEHDAKIAAYV..GD.....LAGAKT.Y.A.S.K.LVNEGGAIHVDGEGTVLLTETVQ
53 -----QAHGRDARVAGFV..AG.....RAGALP.L.R.S.G.LVLEGGGIEVDGEGTAIITESCV
54 ----Y-PSNLDNQVNFKLksLG.....FLKHPL.K.T.M.P.YILEGGSIESDGAGSVLTNTQCL
55 ----Y-PSNLDNQVNFKLkhLG.....FLKHPL.K.T.M.P.YILEGGSIESDGAGSILTNTQCL
56 ----YV-LDHDTEVAAAV..AA.....TADLPT.Y.S.F.P.WVLEGGSVEVDGEGTCLTTRQCL
57 YPANYDNQITQNIVCEAF..KNt10riFSSYRP.I.K.T.D.MILEGGSIESNGAGVLLTNTQCL
58 FEASLDDQLVSSLDAASV..--.....FVPADV.Q.T.V.D.FALEGGAIETDGAGTLLTTWKCL
59 FAAHHDNLITRRLHALGL..FA.....-EGVTLdN.R.L.A.FVLEGGALETDGEGTLLTTDSCL
60 ----YQ-LAGDSDLAIRL..AL.....LMGIPY.G.S.V.P.LFLEGGAIEVDGEGTCLTTRQCL
61 -----QQHSKDAKIAKRV..AA.....DAQATY.Q.R.S.E.LVGEGGGIEVDGHGTAIMTESCW
62 -----TPYKNDARIRENV..SK.....QAGIER.I.D.W.GkFVLEGGAIELDSNGTALLTRSAV
63 -----TPYKNDARIRENV..SK.....QAGIER.I.D.W.GkFVLEGGAIELDSNGTALLTRSAV
64 -----TPYKNDAQIRKNV..SK.....QSGIER.V.D.W.GkFVLEGGAIELDSNGTALLTRSAV
65 ----Y-SLEGDDIVAEQI..AA.....ASGAPL.V.R.N.D.FILEGGALDHDGNGTILTTRQCL
66 ---SWSRWEDDARVARFV..AG.....RTGTPV.S.S.S.P.LTQEGGGFHVDGAGTVLLTDTVQ
67 ----YEPFDSDAAAGAEI..AK.....IAGLKR.L.D.G.G.LTMEGGALETDGAGRLLVNPGCL
68 -----SAYAQDASLARRI..LD.....GLGLEC.F.G.V.P.LANEGGAIHVDGEGTLITTESVL
69 ----Y-PYKKDAVMPAKI..SE.....MYSIPK.V.K.S.S.VCLEGGGIEINGNGTLMAAKTSI
70 ----YQPYDGCQQAGQDI..AR.....AAGAEI.F.N.S.H.MVLEGGSFYVDGQGTLVTTESCL
71 FQSELDNAVNSKLFKEKF..KE.....----EL.K.K.V.D.FILEGGSIDFNGEGVMLTSSHCL
72 ----Y-NLDGDQTIGRDL..AK.....DTALPV.L.E.K.N.WVLEGGSIDGDGHGLVVTTEECL
73 LAATDPAAMTDEQVDRKV..AG.....DLDLPI.L.R.S.S.LISEGGNREFNGKGTLMLTEAVE
74 ----YL-MPGDQEIGADL..AK.....SAGLAT.H.G.KaD.WILEGGALDGDGTGLVATTEQCL
75 VDGLYSPWDKDDAVARKV..CE.....TLGDDS.Y.R.A.P.IVLEGGSIHVDGEGTLYTTEECL
76 ----Y-PAALDTLVGKKL..QP.....WLGDVV.R.E.S.E.YFFEGGALEINDSGVLLANKDCV
77 AGKFFQPFGRDNTVAGWM..AQ.....RKGASL.I.R.S.T.LTLEGGAIEFDGDATAILTESSV
78 -----RPRPNDDEFPKYE..AQ.....YLGIEM.F.G.M.K.LKQTGGNYMTDGYGSAVQSHIAY
79 -----RPRPNDDEFPKYE..AQ.....YLGIEM.F.G.M.K.LKQTGGNYMTDGYGSAVQSHIAY
80 LPDD-QGRYLDQQFNKWL..KK.....-NDFEY.V.K.S.P.LILDGGNLIWNKKDTVILTER-I
81 LPGD-QGRYLDQHFNKWL..KK.....-NDFEY.V.K.S.P.LILDGGNLIWNKKDTIIVTER-I
82 LPDD-QGRYLDQQFNKWL..KK.....-NDFEY.V.K.S.P.LILDGGNLIWNKKDTVILTER-I
83 EEGCYSDWSLD-------..--.....------.-.-.-.-.-----------------------
84 ------------------..--.....------.-.-.-.-.-----------------------
85 ------------------..--.....------.-.-.-.-.-----------------------
86 ------------------..--.....------.-.-.-.-.-----------------------
190 200 210 220
| | | |
1 LNKNRNPHM.....SKEQIEEELKKYLGVQSFIWLPR.....G...L...YG.....DE.....D
2 LNKNRNPHM.....SKEQIEEELKKYLGVQSFIWLPR.....G...L...YG.....DE.....D
3 LNKNRNPHM.....SKEQIEEELKKYLGVQSFIWLPR.....G...L...YG.....DE.....D
4 LNRNRNPHL.....TREQIEAVLSDYLAVDKIIWLPD.....G...L...FN.....DE.....-
5 LNKNRNPHM.....SKEQIEEELKKYLGVQSFIWLPR.....G...L...YG.....DE.....D
6 LNRNRNPHL.....GREEIEAMLSENLSVDKIIWLPD.....G...L...FN.....DE.....-
7 LNHNRNPHL.....SQAEIERTLRDYLAVESIIWLPN.....G...L...YN.....DE.....-
8 LNRNRNPHL.....TREQIETILGDYLAVDKVIWLPE.....G...L...FN.....DE.....-
9 LSEGRNPNL.....TKIEIEQTLKKYFHVQKVIWLKH.....G...F...YL.....DE.....-
10 LSDGRNPQL.....SKEQIESILKEYLNVEKIIWLKK.....G...I...YL.....DE.....-
11 LSEGRNPNL.....TKIEIEQTLKKYFHVQKVIWLKH.....G...F...YL.....DE.....-
12 LSEGRNPQL.....SKQQIEMVLKEYLNLEKIIWLKR.....G...I...YL.....DE.....-
13 LSEGRNPQL.....SKQQIEMVLKEYLNLEKIIWLKR.....G...I...YL.....DE.....-
14 LNRNRNPHL.....SREQIEAVLRDHLAVDTVVWLPD.....G...L...YN.....DE.....-
15 LSEGRNPQL.....SKQQIEMVLKEYLNLEKIIWLKR.....G...I...YL.....DE.....-
16 LSEGRNPNL.....TKIEIEQTLKKYFHAQKVIWLKH.....G...F...YL.....DE.....-
17 LSEGRNPNL.....TKIEIEQTLKKYFHAQKVIWLKH.....G...F...YL.....DE.....-
18 LNPNRNPHL.....SREEIEAVLAGHLAVERVIWLPQ.....G...L...YN.....DE.....-
19 LNENRNPDL.....TKEQIEENLKEYCGVEKVIWLPL.....G...V...YN.....DE.....-
20 LHPSRNPHL.....TKEDIEDKLKDYLNCVKVLWVKD.....G...I...-D.....PY.....E
21 LSEGRNPHM.....SKEDIENKLKEHLNAEKILWLGD.....G...I...-D.....PE.....E
22 LNPNRNPHL.....NQAQIEQLLCDYLGVTHFIWLQD.....G...V...YN.....DE.....-
23 LNPNRNPHL.....NQAQIEQLLCDYLGVTHFIWLQD.....G...V...YN.....DE.....-
24 LNPNRNPNM.....TKLEIENELKDFLGVAKVIWIPH.....G...L...YG.....DD.....D
25 LSPGRNPQL.....SKAQIEEQLKVYLGIEKIIWLPN.....G...L...FN.....DE.....-
26 LNANRNPEL.....TKEQIEGLLRDYLNVKQFIWLQD.....G...V...YM.....DE.....-
27 LSPGRNPNL.....TKEEIENTLLESLGAEKVIWLPY.....G...I...YQ.....DE.....-
28 LSPGRNPNL.....TKEEIENTLLESLGAEKVIWLPY.....G...I...YQ.....DE.....-
29 LNRNRNQHL.....GKDEVTRRLTDYLGAEQVIWLPR.....G...C...KF.....DE.....-
30 LSEGRNPQL.....SKEAIEQKLCDYLNVEKVLWLGD.....G...I...-D.....PE.....E
31 LNRNRNPHL.....DRAAIEAVLADHLAVDKIIWLPD.....G...L...FN.....DE.....-
32 LNPNRNPHL.....DRAAIEQRLREMLGVHTILWLGE.....G...I...VG.....DD.....-
33 --HERHPQR.....TRTTLDANLTAWLAQNRVLWLEH.....G...Y...LE.....GD.....D
34 --HERHPQR.....TRTTLDANLTAWLAQNRVLWLEH.....G...Y...LE.....GD.....D
35 --HERHPQR.....TRTTLDANLTAWLAQNRVLWLEH.....G...Y...LE.....GD.....D
36 --HERHPQR.....TRKTLDANLTAWLAQNRVLWLEH.....G...Y...LE.....GD.....D
37 LNPNRNPHL.....SRAEIEEALARYLGTERVLWLEN.....G...F...LA.....GD.....D
38 LNPNRNPHL.....SQEQIEISLKEQFGADRILWLEN.....G...W...LA.....GD.....D
39 LNPNRNPSL.....GKAEIEAQLRRYLGIEKVLWLGD.....G...I...AG.....DD.....-
40 LSTGRNPTM.....SQQDIEYYLKEYLNVEKIIWLEY.....G...V...AD.....DE.....-
41 LTDTRNPGL.....SEEGYTFLLSDQLGVKKLHWLDG.....G...L...-E.....ND.....H
42 LNPNRNPSK.....SREQIEEYLEDYYGVEHILWLGE.....G...I...VG.....DD.....-
43 LEANRNPGL.....SREAIAQIIQRQLGGDRLLWLEH.....G...H...LE.....GD.....D
44 LSPHRNGKL.....NQVEIEEYLKSTFHLQKVLWLDH.....G...Y...LA.....GD.....D
45 LNDNRNPGM.....DKGQVEAELKALLGLRKIVWLP-.....G...I...RG.....RD.....I
46 LNDNRNPGM.....DKGQVEAELKALLGLRKIVWLP-.....G...I...RG.....RD.....I
47 LNSNRNPGV.....GQAQCEAELSRLLGLKKIIWLP-.....G...I...AG.....KD.....I
48 LGSGRNPGW.....SREEVEAEIHAKLGTTTAIWLPH.....G...L...AG.....DYgry..G
49 --HERHPQR.....TRESLSSDLATWLAQERVLWLDH.....G...Y...LE.....GD.....D
50 LNPNRNPGV.....SKAEMEEIFSRLLGVKKTIWLP-.....GdpdY...VT.....GD.....M
51 LEANRNPEY.....SKEKIESILTQELGAKKVLWCHH.....G...Y...LA.....GD.....D
52 LGAERNPGW.....TREQVETEIHAHLGTSKAIWLPR.....G...L...TG.....DYpphgfG
53 LNANRNPGW.....SKAQCEGELRRVLGVEKVIWLP-.....G...V...AG.....RD.....I
54 LEKNRNPHL.....NQNGIENMLKKELGAKQVLWYSY.....G...Y...LK.....GD.....D
55 LEKNRNPHL.....NQNGIETMLKKELGAKQVLWYSY.....G...Y...LK.....GD.....D
56 LNPNRNPGM.....DSKAIEQGLKEALGVRKVLWLDE.....G...L...LN.....-D.....H
57 LEKNRNSHL.....SQDEIESKLKEYFGLDSVLWLTQ.....G...Y...LA.....GD.....D
58 --HERHPQR.....SRDSLSSDLATWLAQDRVLWLDH.....G...Y...LE.....GD.....D
59 FEPNRNAGL.....SRTAIIDTLKESLGVSRVLSLRH.....G...A...LA.....GD.....D
60 LNPNRNPYL.....SSAEVEARLKPALGVSKILWIES.....G...L...VN.....-D.....H
61 VNENRNPGW.....SKADVEAELKARLGLRKIIWLP-.....G...I...KG.....KD.....I
62 TNKNRNPDL.....SEKEIEKYISD-LGVSNFIWLD-.....G...V...PN.....LD.....I
63 TNKNRNPDL.....SEKEIEKYISD-LGVTNFIWLD-.....G...V...PN.....LD.....I
64 TNKNRNPDL.....SEKEIEKYISD-LGVSNFIWLD-.....G...V...PN.....LD.....I
65 LNDNRNPGW.....DEATANAALTEALGAKKVLWLGK.....G...L...KN.....-D.....H
66 LDPGRNPGW.....TREQVEAEVHAQLGTTTAIWLPR.....G...LtadYG.....EF.....G
67 VDPARNPGV.....SKEQVSQRLNQCLGVEEIVWVDG.....G...A...PA.....GD.....D
68 LNANRNPGL.....SKAEIEALFARLLGVTRTIWLP-.....G...D...PDrvt..GD.....M
69 INENRNPTL.....SQEEIEIELTKYLGVTNFIWIT-.....G...I...RGedny.DE.....D
70 LHPNRNPHL.....SRAEIEAELRRMLGVEKIIWLP-.....G...N...PD.....EV.....E
71 LNENRNSHL.....NKTQIDTKLKEIFGLKQIIWLEN.....G...F...IK.....GD.....D
72 LNPNRNPEL.....SRGDIARHLRNDLGYDRVLWLRK.....G...L...HN.....-D.....H
73 L--QRNPGL.....TKEKIETELKRVFNLKKVIWLQE.....G...V...ID.....DEl15vlA
74 LNPNRNPHL.....SRGDLEARLLRDLGYDRVLWLGD.....G...L...IN.....-D.....H
75 LHPSRNPDL.....TREEIEDVLKVTLSIEKVIWIPQ.....G...L...YN.....DE.....-
76 IDTHRNPGL.....NQAAVEAILAKELGVKAFAWLE-.....G...Iq..LT.....GD.....D
77 LHVNRNPQLf16ptAKDTVLAELQRTLGVRKIIWLPGta8ssG...V...GGa10geTD.....I
78 TE---NSSL.....SQAQVNQKMKDYLGITHHDVVQD.....-...-...PN.....GE.....Y
79 TE---NSSL.....SQAQVNQKMKDYLGITHHDVVQD.....-...-...PN.....GE.....Y
80 FDD--NDDW.....TEEEIIEQLEWDLDVSRVIIIP-.....-...-...AE.....EG.....D
81 FDD--NDDW.....TEEEIIEQLEWDLDVSRVIIIP-.....-...-...AE.....EG.....D
82 FDD--NDDW.....TEEEIIEQLEWDLDVSRVIIIP-.....-...-...AE.....EG.....D
83 ---------.....-----------------------.....-...-...--.....--.....-
84 ---------.....-----------------------.....-...-...--.....--.....-
85 ---------.....-----------------------.....-...-...--.....--.....-
86 ---------.....-----------------------.....-...-...--.....--.....-
230 240 250 260 270
| | | | |
1 TNGHIDNMCCFARPGVVLLS...WTDDETDP....QY..ERSVEALSVLSNSIDARGRKIQVIKL
2 TNGHIDNMCCFARPGVVLLS...WTDDETDP....QY..ERSVEALSVLSNSIDARGRKIQVIKL
3 TNGHIDNMCCFARPGVVLLS...WTDDETDP....QY..ERSVEALSVLSNSIDARGRKIQVIKL
4 TDGHVDNFCCYIRPGEVLLA...WTDDPEDP....NY..PRCHAALSILENTRDAQGRAFIVHKM
5 TNGHIDNMCCFARPGVVLLS...WTDDETDP....QY..ERSVEALSVLSNSIDARGRKIQVIKL
6 TDGHVDNFCCYVRPGEVLLA...WTDDPQDP....NY..PRCQAAMKVLESSTDAKGRPFTVHKM
7 TDGHVDNFCCYARPGEVLLA...WTDDQDDP....NY..LRCQAALRVLEESRDAKGRKLVVHKM
8 TDGHVDNFCCYIRPGEVLLA...WTDDPEDP....NY..SRCHAALSILENTLDAKGRAFIVHKM
9 TNGHVDNIFNFVAPGEVVLS...WTDNKSDP....QY..EISRECYDILANQTDAKGRTFIIHKL
10 TNGHVDNIANFVKPGQVVLA...WTDDQSDP....QY..AISKENYDMLINETDAKGRKLQVEKL
11 TNGHVDNIFNFVAPGEVVLS...WTDNKSDP....QY..EISRECYDILANQTDAKGRTFMIHKL
12 TNGHVDNIFNYVRPGVVALA...WTDDETDP....QY..EISKECFDILSNETDAKGRKLEVHKI
13 TNGHVDNIFNYVRPGVVALA...WTDDETDP....QY..EISKECFDILSNETDAKGRKLEVHKI
14 TDGHVDNFCCYVRPGEVLLA...WTDDSNDP....NY..ARCHAAMDVLKNTRDAKGREFIVHKM
15 TNGHVDNIFNYVRPGVVALA...WTDDETDP....QY..EISKECFDILSNETDAKGRKLEVHKI
16 TNGHVDNIFNFVAPGEVVLS...WTDNKSDP....QY..EISRECYDILANKTDAKGRTFIIHKL
17 TNGHVDNIFNFVAPGEVVLS...WTDNKSDP....QY..EISRECYDILANKTDAKGRTFIIHKL
18 TDGHVDNFCCFVRPGEVLLA...WTDDPQDP....NH..PRCRAALEVLERVRDARGRALRVQRM
19 TNGHVDNLLNVVSPGHVVLT...WTDDTTDP....QY..ERSKLAYDILTNTLDAKGRKIKVTKL
20 TNGHIDDVACFIRPGEVACI...YTDDKEHP....FY..QEAKAAYDFLSQQTDAKGRPLKVHKM
21 TNGHVDDVACFVAPGEVACI...YTEDEKSP....FY..EAAQDAYKRLNQMTDAKGRQLKVHKL
22 TDGHIDNMCCFVRPGEVALH...WTDDQQDP....QY..ARSVAAFEVLSNTVDAKGRKLKIWKL
23 TDGHIDNMCCFVRPGEVALH...WTDDQQDP....QY..ARSVAAFEVLSNTVDAKGRKLKIWKL
24 TNGHVDNLCCFIKPGVVLLS...WTDDENDP....QY..QRSVDALSTLSKSVDAKGRQIEVVKI
25 TDGHVDNLMHVIAPGKVVLS...WTDDPSDP....QY..ALSRQAEQVLKSQHDAKGREIEIVRL
26 TDGHIDNMCCFARPGEVILH...WTDDESDP....QY..PRSKAALEVLQNTVDAQGRKLKIHLL
27 TNEHVDNVVAFVGPAEVVLA...WTDDENDP....QY..AMSKADLELLEQETDAKGCHFTIHKL
28 TNEHVDNVAAFVGPAELVLA...WTDDENDP....QY..AMSKADLELLEQETDAKGCHFTIHKL
29 TDGHVDDLACFVRPGEVVLQ...WTDNRDDP....QW..EIYQEAYDILRSTRDSRGRELIVHKL
30 TNGHVDDVACFIAPGEVACI...YTEDQNSP....FY..EAAQDAYQRLLKMTDAKGRQLKVHKL
31 TDGHVDNFCCYVRPGEVLLA...WTDDPQDP....NY..PRCHAAMDVLQNSTDAKGRAFIVHKM
32 TDGHIDDLARFVAPGVVVTV...VEDDPLDE....NY..HVLQDNLRRLQLMRDAAGRPLTVLTI
33 TDAHIDTLARFASTDSIVYQ...SCDNTTDS....HY..AELQAMANELTALRTTEGRPYRLFPL
34 TDAHIDTLARFASTDSIVYQ...SCDNTTDS....HY..AELQAMANELTALRTTEGRPYRLFPL
35 TDAHIDTLARFASTDSIVYQ...SCDNTTDS....HY..AELQAMANELTALRTTEGRPYRLFPL
36 TDAHIDTLARFASTDSIVYQ...SCDNTTDS....HY..AELQAMANELTALRTTEGRAYRLFPL
37 TDSHVDTLARLAPDDTIVYV...RCDDATDE....HY..AALFMMEKELANLRTREGSPYRLIPL
38 TDSHIDTLARLAPDDTIVYV...RCDDAADE....HY..PALFLMEKELKAMRTSEGSPYRLIPL
39 TDGHVDDMARFVNENTVVIA...VEEDPEDE....NY..KPLRENYELLKTMTGLDGKPLNIVKL
40 TNGHVDNMACFSRPGEVILA...WTDDPKHP....QY..ERSKNAYKLLTKERDAKGRKLIIHKI
41 TDGHIDTITRFAAENVIVTS...VEADPNDA....NH..AVMQRNLATLRELRTPGGDFYQIVEL
42 TDGHIDDITRFVNEDTVVTV...VEENKSDD....NY..FLLKDNLKDLHKMRLENGKQLNVIEL
43 TDAHIDTLVRIAPNDTLIYV...ACDDPSDS....HA..AELTALEAELKALRAADGQPYHLIPL
44 TDSHIDTLARFCSTDTIAYV...KCDNTEDE....HY..EALHAMEEQLKTFRTLAGEPYRLLAL
45 TDAHVDFYARFVRPGVVIAN...LDNDPDSY....DY..AVTREHLEILRTATDADGRALQVHTL
46 TDAHVDFYARFVRPGVVIAN...LDNDPDSY....DY..AVTREHLEILRTATDADGRALQVHTL
47 TDGHTDFYARFTSPGVVVAG...LDTDPSSY....DH..AVTRQHLEILRKSTDAKGRPLKVVVL
48 TQGHVDIVAAFARPGTVVVH...SQRDPRHP....DH..ERSQLYLEILRGRTDARGRRLEVVEV
49 TDAHIDTLARFAGPDAIVYQ...GCDVASDS....HY..VELQAMGAELAALRKADGQPYRLFVL
50 TDGHVDGVCAFARPGVLLVD...ATHDCSSV....YA..EVVRENRRALELATDAQGRKFELIEL
51 TDSHIDTLARFVGENRIVYL...KCEDESDE....HY..KELKQMEEELKELRGVDGEPLELIPL
52 TLGHVDIVAAFARPGVVVAH...HQPDPAHP....DH..EVSKEVIGLLKAATDAHGRRIEVVEV
53 TDGHTDFYARFARPGVVVAG...LETDPASY....DY..QVTRRHLAMLRQARDARGRKLEVVAI
54 TDSHTDTLARFLDKDTIVYS...TCEDENDE....HY..TALKKMQEELKTFKKLDGTPYKLIPL
55 TDSHTDTLARFLNKDTIVYS...ACEDENDE....HY..TALKKMQEELKTFKKLDGTPYKLIPL
56 TDGHIDTIARFAAPGVVVCM...QAA-PDDP....NA..PVLDNIAATLAGFTDAAGRMLTVVRV
57 TDSHIDTLARFISEDTIAYI...TCDDKQDE....HF..ESLKSMEAELRALKQSNGEPYKLIPL
58 TDAHIDTLARFAGADAIVYQ...GCAVPSDS....HY..AELQAMGEELAALRKADGQPYRLFVL
59 TDGHIDTLARFVDTRTIVYV...RSEDPSDE....HY..SDLTAMEQELKELRRPDGQPYRLVPL
60 TDGHIDTLVRFVAPATVVCM...LAESPEDP....NC..DVLRTIYEQLQTLTDAKGRSLEVIPV
61 TDAHVDFYARFVTPGVVIAN...LDTDPRSY....DN..KVTLAHLEILKKATDADGRPLQIHTV
62 TDFHIDGFAKFHNKSTIVTM...KEDDLAE-....-W..GLSNKDMDTLLDAKNAAGKKYKYEYL
63 TDFHIDGFAKFHNKSTIVTM...KEDDLAE-....-W..GLSNKDMDTLLDAKNALGKKYKYEYL
64 TDFHIDGFAKFHNKSTIVTM...KEDDLAE-....-W..GLSNKDMDTLLDAKNASGQKYKYEYL
65 TDGHVDNLARFVAPGVVACP...MGYGLDDP....NA..DIYGDTAKMLAGMTDSRGSPLQVVRI
66 TRGHVDIVAAFTPSGAVLVH...TQPDPGHP....DH..AVTQEVTEVLRGARDARGERLEVVEL
67 TDGHIDQIARFLNRENVVCA...VASSEVDE....NY..PGLEANYRKLRLWSRQTEPAVTIHRL
68 TDGHVDGVCAFARPGALLLD...ATCDTTSA....YA..EVVRENRRALELALDARGRRFELIEL
69 TDYHIDGAARFVNENTILYE...YDPFGEGE....PYllDAYEKHYQELRQARNLDGKPFQLIPV
70 TNGHVDGIASFIAPGRMLCQ...TALPEQGD....YF..HVMRENRRALELATDAAGRRFELLDL
71 TDHHIDTLARFIDKNTIAHC...ICEDEEDE....HY..LPLQKMKEELKKT----G--FDLLEL
72 TDGHVDNLARFVGENHLVVP...IATDQDDP....NR..EVYDQAAQIATEF----G--VKVTRI
73 TGGHIDEYARFVDSNTILLAevtAEERASDPlaaiNY..QRLEENLKILQAATDQDGKPFRIVRI
74 TDGHVDNLARFVGPNRLALP...RATGPNDP....NA..AIYADAR---ARALDA-G--VEVVEV
75 TNGHVDNLIHVVRPGEIALT...WCDDETDP....QY..LISRKAMDVLLTETDAKGRQIKIHKL
76 TDGHIDTIARYVANDSVVYS...-GPNPSHP....DA..AALLALKSQISALAAVH--NWQLAEL
77 TNGHVDFYARFLAPGVVACC...YDASNSTG....ER..ALTDANRQRLAGETDANGRPLQIVEL
78 IN-HVDCWGKYLAPNKILIR...KVPD-NHP....QH..QALEDMAAYFAAQTCAWGTKYEVYRA
79 IN-HVDCWGKYLAPNKILIR...KVPD-NHP....QH..QALEDMAAYFAAQTCAWGTKYEVYRA
80 VLAHADGMVKFIGEHTMFIS...DFLGDDEF....RY..HV-QEIIQ--EQMPEAE---FIVV--
81 VLAHADGMVKFIDEHTMFIS...DFLGDHEF....RY..HV-QEIIQ--EQMPEAE---FIVV--
82 VLAHADGMVKFIDEHTMFIS...DFLGDHEF....RY..SV-EEIIQ--EQMPEAE---FIVV--
83 --------------------...--------....--..--------------------------
84 --------------------...--------....--..-DHVALESELQELRTLEGNPYRLLRL
85 --------------------...--------....-M..EAYEKHYQELRQAKNIDGKPFQLIPV
86 --------------------...--------....--..--------------------------
280 290 300 310 320
| | | | |
1 YIPE.PLY..MTEEES.....SGITQDGEAIPRLAGT...RLAAS..YVNFY.IANGGIIAPQFG
2 YIPE.PLY..MTEEES.....SGITQDGEAIPRLAGT...RLAAS..YVNFY.IANGGIIAPQFG
3 YIPE.PLY..MTEEES.....SGITQDGEAIPRLAGT...RLAAS..YVNFY.IANGGIIAPQFG
4 PIPG.PLF..ATEEEC.....AGVDQVHGSQERNPSV...RLAGS..YVNFL.IVNGGIIAPSFD
5 YIPE.PLY..MTEEES.....SGITQDGEAIPRLAGT...RLAAS..YVNFY.IANGGIIAPQFG
6 PIPG.PLF..ATEEEC.....AGVDPVDGTQERNPSV...RLAGS..YVNFL.IVNGGIIAPSFD
7 PIPG.PLY..ATQEEC.....DGVDIVEGSQPRDPSI...RLAGS..YVNFL.IVNGGIIAPSFD
8 PIPG.PLF..ATEEEC.....AGVDQVHGSQERNPSV...RLAGS..YVNFL.IVNGGIIAPSFD
9 HCPD.PVL..ITQTES.....EGVEAINGTFPRQAGD...RLAAS..YVNYY.TANGAIIFPLFD
10 YLPK.PIL..ITEAES.....QGVDTVDGTLPRLAGD...RLAAS..YVNYY.TANGGIVFPLFN
11 HCPD.PVL..ITQTES.....EGVEAINGTFPRQAGD...RLAAS..YVNYY.TANGAIIFPLFD
12 NVPK.PIL..ITDEES.....KGVDAVEGTLPREEGD...RLAAS..YINYY.TANGGVVFPLFG
13 NVPK.PIL..ITDEES.....KGVDAVEGTLPREEGD...RLAAS..YINYY.TANGGVVFPLFG
14 PIPG.PLF..ATAEEC.....AGVDQVAGSQERDPSV...RLAGS..YVNFL.IVNGGIIAPSFD
15 NVPK.PIL..ITDEES.....KGVDAVEGTLPREEGD...RLAAS..YINYY.TANGGVIFPLFG
16 HCPD.PVL..ITQTES.....EGVEAINGTFPRQAGD...RLAAS..YVNYY.TANGAIIFPLFD
17 HCPD.PVL..ITQTES.....EGVEAINGTFPRQAGD...RLAAS..YVNYY.TANGAIIFPLFD
18 PIPG.PLH..ASAEEC.....AGVDPAADSQPRDPSI...RLAAS..YVNFL.IVNGGIIAPAFD
19 HQPG.PLF..ITKEEA.....EGID-VCDTMSREPEQ...RMPAS..YANYY.IANNAIILPIFG
20 CVTK.EPC..YLQE-A.....ATIDYVEGSIPREEGE...MAIAS..YLNFL.IVNGGIILPQYG
21 TCPA.K-N..VTIKKQ.....FRIDTVEGTMPREDGD...ICIAS..YMNFL.ITNKGVIVPQYG
22 PAPG.PLY..NTEEET.....FDV-LTSDAVPRTAGE...RLAGS..YVNFL.ISNQQIIFPLLD
23 PAPG.PLY..NTEEET.....FDV-LTSDAVPRTAGE...RLAGS..YVNFL.ISNQQIIFPLLD
24 HVPG.PLY..MTKEES.....EGVVKTEHAIPREPGT...RLAAS..YVNFY.IANGGIVAPAFG
25 PLPG.PLH..YSEREA.....NGIDASSG-MSRQAGE...RLSAS..YANFL.IVNGHVFLPML-
26 PQPG.PLY..CSEEES.....KGVT-EGTGVPRTAGE...RLAGS..YVNFL.ITNHRIVFPLL-
27 PIPAvRQV..VTEEDL.....PGYIYEEGEEERYAGE...RLAAS..YVNFY.IANKAVLVPQFE
28 PIPAvRQV..VTEEDL.....PGYIYEEGEEKRYAGE...RLAAS..YVNFY.IANKAVLVPQFE
29 PQPD.VLE..WTAEEA.....EGLDQQDSTHTRQAGT...KICAS..YINYY.AGNSSIVVPLFG
30 CCP-.VKN..VTIKGS.....FKIDFVEGTMPREDGD...ICIAS..YMNFL.ITNDGVIVPQYG
31 PIPG.PLY..ATEEEC.....AGVDPVDGSQERNPSV...RLAGR..NVNFL.IVNGGIIAPSFD
32 PMPP.PVV..F-----.....-------------QGQ...RLPAS..YANFY.IANHAVIVPTFN
33 PWTK.PIL..------.....------------DQDR...RLPAS..YANFL.IIEGAVLMPTYN
34 PWTK.PIL..------.....------------DQDR...RLPAS..YANFL.IIEGAVLMPTYD
35 PWTK.PIL..------.....------------DQDR...RLPAS..YANFL.IIEGAVLMPTYD
36 PWTK.PIL..------.....------------DQDR...RLPAS..YANFL.IIEGAVLMPTYD
37 PWPR.ACF..------.....-----------DHEGQ...RLPAT..YANFL.VINGAVLVPVYD
38 PWPR.PCH..------.....-----------DEDGE...RLPAT..YANYL.VINGAVLVPTYG
39 PMPE.PVY..Y-----.....-------------DGE...RLPAS..YANFY.IANTVVLVPTYR
40 HIPS.DMF..ITEEEA.....TGVVNSGLAVPRRAGD...RLAAS..YVNFV.MPNGAIIFPTFG
41 PLPA.HRL..------.....-----------EGAEG...RLPPT..YANFY.IGNGFVVVPQYG
42 PMPS.AVI..Y-----.....-------------DDQ...RLPAS..YANFY.ISNNHVVVPTFR
43 PWPQ.PCF..------.....-----------DADGQ...RLPTT..YANYL.VINGAVLVPTYN
44 PMAD.KV-..------.....-----------EEDGE...RLPAT..YANFL.IMNDAILYPTYQ
45 S-P-.PLK..PRRDY-.....-----------SRNNP...DFAAG..YINYL.PINGAVIAPQFG
46 S-P-.PLK..PRRDY-.....-----------SRNNP...DFAAG..YINYL.PINGAVIAPQFG
47 PGPK.SVR..H-----.....-----------QYENE...EFAAG..YINFY.VCNRAVIAPQFG
48 PAPT.VLK..------.....-----------DEEGE...WADYS..YINHY.VCNGGVVLCAFG
49 PWAQ.PIL..------.....------------DEGR...RLAAS..YANFL.IVNGAVLMPAYG
50 YEAT.DAV..------.....-----------DTEAE...VFCAS..YTNFY.IANGAIIMPAYG
51 PFTK.AIY..Y-----.....-------------DGE...RLPAS..YANFL.FVNGAVLLPIYG
52 PAPT.VL-..------.....-----------EADGH...WADYS..YINHY.LCNGGVVLCGFD
53 PGPD.RVR..------.....----------PEYEDD...EMAAG..YINFY.VCNGAVIALEFG
54 EIPK.AIF..------.....-----------DENQQ...RLPAT..YVNFL.LCNNALIVPTYN
55 EIPK.AVY..------.....-----------NENQQ...RLPAT..YVNFL.LCNNALIVPTYN
56 PSPG.RVV..------.....-----------DDNGE...VMPAS..YVNFY.IANRTVAVPTYG
57 PFTQ.AIY..------.....-----------DEQGQ...RLPAS..YANFL.FVNGGLLVPTYG
58 PWAE.PIL..------.....------------DQGR...RLAAS..YANFL.IVNGAVLMPAYG
59 PMAE.ALY..------.....------------DGAD...RLPAT..YANFL.IINGAVLVPTYD
60 PSPG.RVT..------.....-----------SQKGE...ILPAS..YVNFY.IANTTVVVPTYG
61 S-P-.PLK..PRKTKF.....-----------NKDND...DFAAG..YINYF.VINGAVIAPEFG
62 PLSK.EKV..V-----.....---------LENGKTL...DYKGS..YINYY.IGNTVVLVPNYN
63 PLSK.EKV..V-----.....---------LENGKTL...DYKGS..YINYY.IGNTVVLVPNYN
64 PLSK.EKV..------.....--------ALENGKTL...DYKGS..YINYY.IGNTVVLVPNYN
65 PSPG.KLL..------.....-----------DEDGE...PIPAS..HMNFL.IANEAVIVPIYA
66 LAPE.RH-..------.....-----------EVDGE...LVDHS..YVNHY.VANSVVVLCAFD
67 PTPP.PR-..------.....-----------EVDGA...AVPQS..YCNFLrLGMDRMLVPTFR
68 FDAG.EVA..------.....-----------PEEG-...VFCAS..YTNFY.IANGAIIMPAYG
69 PVTR.KVV..------.....-------------KEA...ECKGS..YLNFY.IGNEVVLVPIYG
70 --PS.PIV..------.....---------TERFGSE...RYCDC..YANYI.LVNGAVIVSAFG
71 PIPK.PLY..Y-----.....-------------EER...RLGAT..YANFV.FINNALIVPFYK
72 PSTG.RIT..I-----.....-------------DDE...VVPAS..YMNFY.IGNKVVVVPVYG
73 PAAK.PIYvnMTKEDAvfqalQELTFEDGTVIQDDDQiktILAAS..YLNFV.IANDVVIVPRYW
74 PSPG.RI-..------.....-----------EWGDM...VQPAS..YMNFV.ITSDLVVVPVFG
75 PMPG.PLY..ISEDEA.....NGVDVSEG-MERVPGE...RLAGS..YANYL.ISNEHIIYPLLD
76 --PT.PIV..YSQVE-.....-------------EGQ...LLPAT..YANFL.ICNDVAFVPVYG
77 -VP-.PVN..FG----.....---TSAGTSLNDRQMT...NFAAG..YINFY.ACNGAIVMPKFN
78 LATN.E--..------.....----------------...---QP..YTNSL.ILNNRVFVPVNG
79 LATN.E--..------.....----------------...---QP..YTNSL.ILNNRVFVPVNG
80 --PS.S--..YTEKG-.....-----------QYDQE...IASAKglYINML.ETCDALYVPKFG
81 --PS.S--..YTEKG-.....-----------QYDQE...IASAKglYINML.ETCDALYVPKFG
82 --PS.S--..YTEKG-.....-----------QYDQE...IASAKglYINML.ESCDALYVPKFG
83 ----.---..------.....----------------...-----..-----.------------
84 PMPD.AIY..------.....------------DGED...RLPAT..YANFV.ILNGAVIVPTYN
85 PVTR.KVV..------.....-------------KEA...DCKGS..YLNFY.IGNEVVLVPVYG
86 ----.---..------.....----------------...-----..-----.------------
330 340 350 360 370 380
| | | | | |
1 DPIR.....DKEAIRVLSDTFPHHSVVG.IENAREI.VLAGGNIHCI.T.QQQPAEPTSVAEN..
2 DPIR.....DKEAIRVLSDTFPHHSVVG.IENAREI.VLAGGNIHCI.T.QQQPAEPTSVAENg.
3 DPIR.....DKEAIRVLSDTFPHHSVVG.IENAREI.VLAGGNIHCI.T.QQQPAEPTSVAENg.
4 DP-M.....DEKAREILQKLFPEHEVVM.APG-REL.LLGGGNIHCL.T.QQQPAPFKA----..
5 DPIR.....DKEAIRVLSDTFPHHSVVG.IENAREI.VLAGGNIHCI.T.QQQPAEPTSVAENg.
6 DP-M.....DAPAREILQNLFPQHEVVM.VPG-REL.LLGGGNIHCL.T.QQQPAP-------h.
7 DP-K.....DAEARAILQRVFPEHEVVM.VPG-REI.LLGGGNIHCI.T.QQQPAP-------r.
8 DP-M.....DEKAREILQKLFPEHEVVM.APG-REL.LLGGGNIHCL.T.QQQPAP-------h.
9 DP-K.....DKDAQELLEQLYPDRKIVG.IK-AREI.LLGGGNIHCI.T.QHLPDKSTIRE--..
10 DP-M.....DEKAQEILQKLYPDRKIVG.VP-AREI.LLGGGNIHCI.T.QQIPAGR------..
11 DP-K.....DKDAQELLEQLYPDRKIVG.IK-AREI.LLGGGNIHCI.T.QHLPDKSTIRE--..
12 DP-N.....DELAREKLRQLYPNCEVVG.VK-AREI.LLGGGNIHCI.T.QQVPRG-------..
13 DP-N.....DELAREKLQQLYPNCEVVG.VK-AREI.LLGGGNIHCI.T.QQVPRG-------..
14 DP-A.....DAEARAILARIFPDHEVVM.IPG-REL.LLGGGNIHCL.T.QQQPAPV------k.
15 DP-N.....DELAREKLQQLYPNCEVVG.VK-AREI.LLGGGNIHCI.T.QQVPR--------..
16 DP-K.....DKDAQELLEKLYPDRKIVG.IK-AREI.LLGGGNIHCI.T.QHLPDKSTIRE--..
17 DP-K.....DKDAQELLEMLYPDRKIVG.IK-AREI.LLGGGNIHCI.T.QHLPDKSTIRE--..
18 DP-R.....DAEAEALLRQSFPGREVLM.LPG-REI.LLGGGNIHCI.T.QQQPAARR-----..
19 DK-Y.....DDLAVKTLQSVYPNHKIET.VM-AREI.LLGGGNIHCI.T.QQQPTTK------..
20 DE-N.....DQLAKQQVQEMFPDRKVVG.VR-TEEI.AYGGGNIHCI.T.QQQPAT-------..
21 DE-N.....DALALKQVQEMFPDREIVG.VNTV-EV.VYGGGNIHCI.T.QQQPKAK------..
22 SR-T.....DGQANDLLQQMFPGYAIVG.VP-AREI.LLGGGNIHCI.T.QQIPAA-------..
23 SR-T.....DGQANDLLQQMFPGYAIVG.VP-AREI.LLGGGNIHCI.T.QQIPAA-------..
24 DK-W.....DEEACAVLQKAFPDHEVIF.TDPFHFE.TLSSDAV--I.SvCQRPQLKQAVAVGcy
25 DEDT.....DAIAIDILQNAMPEYQIIA.IPS-REV.LLGGGNIHCI.T.QQIPA--------..
26 DPAT.....DDIAAQKLQEIFPEHEIVG.VP-AREI.LLGGGNIHCI.T.QQIPAGK------..
27 DV-N.....DQVALDILSKCFPDRKVVG.IP-ARDI.LLGGGNIHCI.T.QQIPE--------..
28 DV-N.....DQVALDILSKCFPDRKVVG.IP-ARDI.LLGGGNIHCI.T.QQIPE--------..
29 DR-N.....DQVALATLAELFPQHKIVG.IENSREI.LLGGGNVACI.T.MPQYAG-------qk
30 DE-N.....DHLALEQVQTMFPDKKIVG.VNTV-EV.VYGGGNIHCI.T.QQEPKR-------..
31 DP-L.....DHTGQTNPAEPVPAAR--S.SDGAGPR.TVTGGRQY--.-.-------------..
32 HP-N.....DQRACAVLQQCFPDRRVVG.IE-ATDV.IWGLGSWHCL.S.QQVPAGLINV---..
33 DP-A.....DTIAQSVLAEAFPTREIVP.VP-CRPL.IWQNGSLHCI.T.MQIPAGLLAT---..
34 DP-A.....DTIAQSVLAEAFPTREIVP.VP-CRPL.IWQNGSLHCI.T.MQIPAGLLAT---..
35 DP-A.....DTIAQSVLAEAFPTREIVP.VP-CRPL.IWQNGSLHCI.T.MQIPAGLLAT---..
36 DP-A.....DTIAQSVLAEAFPTREIVP.VP-CRPL.IWQNGSLHCI.T.MQIPAGLLAT---..
37 DP-A.....DEAALEAIGRAFPGREIVG.ID-CRPL.IIQHGSLHCV.T.MQLPKGVLPC---p.
38 DP-G.....DDAALAAIGQAFPGREIIG.ID-CRPL.ILQHGSLHCV.T.MQLPKGTLAPEPRnv
39 CP-R.....DQQAIDILQQCFPKREVVG.ID-CSDL.IWGLGAIHCV.T.HEEPAM-------..
40 DEKY.....DALAHKKFEEIFPEREIVGfIHG-RSS.SVEG--I-CIvS.L------------..
41 DP-N.....DKQALDVLRPLFPGREVIG.VPS-RKI.IEGGGSFHCL.T.QQQPAGRVWS---g.
42 DK-N.....DEVALEILQQLFTDRKVTG.LDS-TDI.IWGLGSFHCL.S.QQEPA--------..
43 DP-A.....DEAAIAAIAAAFPDRLAIG.IN-CRPL.LEQHGSLHCI.T.MQLPAGLLSR---..
44 QPDN.....DRKAGEVLQQAFPKHQVIG.ID-CRAL.IKQHGSLHCV.T.MQYPSGVIQ----..
45 DASA.....DRHCGELLGRLYPGRDIVQ.LN-IDPI.AAGGGGIHCV.T.KHMPRA-------..
46 DASA.....DRHCGELLGRLYPGRDIVQ.LN-IDPI.AAGGGGIHCV.T.KHMPRA-------..
47 DSRA.....DRNTRDTLVDLFPGREVIQ.LN-IDGI.AAGGGGIHCT.T.QQQPA--------..
48 DP-N.....DELAAGIFRRLFPERTVTL.VD-ARTI.FAGGGGIHCI.T.QQQPRT-------..
49 DA-A.....DATAQAVLAQAFPHHEIVP.VP-CRAL.IWQNGSLHCL.T.MQLPAGLLAA---..
50 IE-A.....DHVAAQTLAEAFPGREVVP.VQ-INHL.AHGGGGVHCI.T.QQQPAWPV-----e.
51 DE-K.....DQEAIRTMKRACPNHEIVP.ID-CRVL.IRQHGSLHCV.S.MQLVEGMV-----..
52 DP-R.....DETAAGIFRRLFPERTVTL.VD-ARTI.FSGGGGIHCI.T.QQQPKN-------..
53 DARA.....DRNARSALRELFPEREVVQ.LN-IDAI.AAGGGGIHCA.T.QQQPA--------..
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57 DK-N.....DKKALEILSLALPTRRVVG.VD-CRSL.ILWHGSLHCV.S.MQVYDTL------..
58 DA-A.....DAAAQAVLADAFPQHQIVP.VP-CRPL.IWQNGSLHCL.T.MQLPAGLLAA---..
59 SH-L.....DAVALSVMQGLFPDREVIG.ID-CRPL.VKQHGSLHCV.T.MQYPQGFIR----..
60 VE-A.....DAKAVEAIAKLFPSRRTIG.LP-ARTI.LEGGGAFHCI.T.QQEL---------..
61 DKDA.....DKKAFDLLKKLYPNRDVVQ.IN-IDAI.AAGGGGIHCV.T.SHQPA--------..
62 DP-N.....DKIANDTIQKLYPDRKIVG.ID-VREL.YKNGGMIHCV.T.QQQPIAMK-----..
63 DP-N.....DKIANDTIQKLYPDRKVVG.ID-VREL.YKNGGMIHCV.T.QQQPIALK-----..
64 DP-N.....DKIANDTIQKLYPDRKVVG.ID-VREL.YKNGGMIHCV.T.QQQPIALK-----..
65 EE-S.....GAFAVEVIKGLFPERQVIG.LPS-TAI.LTGGGSFHCI.S.QQEPETA------..
66 DP-R.....DARARAVLAAAYPDRAVVP.VD-ARDV.FAFGGGIHCI.T.QQQPA--------..
67 STAS.....DQHALALLRELCPGVEVVG.VD-CFDI.AWGLGALHCA.S.CHEPAIARSPAAEss
68 VA-A.....DDAAAATLARAFPAREVVP.VR-IDHL.AHGGGGVHCI.T.QQQPAWP------a.
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75 EK-H.....DKDVAMLLAKLYPNYEVTG.VN-AREI.LLGGGNIHCI.T.QQIPKV-------..
76 VS-E.....DQIAVDVLTTAMPNKTIVT.VR-CEAL.LEQHGSLHCA.T.MQIGAI-------..
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82 LA-K.....DEEVLRYIQQYT-EKQVIQ.IH-VGEI.STMGGAMNCL.T.WYCPSHLLPSKMRrl
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85 DE-H.....DKLGLQIIEGQFPGRRIVG.IY-VNEL.YAYGGMIHCV.T.QQHIE--------..
86 ----.....-------------------.-------.----------.-.-------------..
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