SetCost wet6.5 3 near_backbone 3 way_back 3 dry5 5 dry6.5 6 dry8 5 dry12 2 \
	phobic_fit 2 \
	sidechain 6 \
	bystroff 5 \
	soft_clashes 10  backbone_clashes 2 \
	break 20  \
	pred_alpha2 5 \
	constraints 10 \
	hbond_geom 0.5 \
	hbond_geom_backbone 1 \
	hbond_geom_beta 0.1 \
	hbond_geom_beta_pair 0.1

# The beta cost functions were down-weighted for this alpha-protein

// Add the following for extra-cellular proteins:
#	known_ssbond 0.5	# and put ssbond command in constraints file
#	maybe_ssbond 0.5

// For comparative modeling, increase weight of break and hbond_geom...

HelixConstraint 	R3	E36	0.6364
HelixConstraint 	E39	L69	0.7096
HelixConstraint 	P76	L107	0.6896
HelixConstraint 	P115	A138	0.65
HelixConstraint 	V142	M171	0.8065
HelixConstraint 	V177	V208	0.7128


# loose constraints for up-down bundle
# These should be made more specific once the bundles start forming.
# Some of the constraints have changed from try2 to attempt to bury the
# one of very hydrophobic helices inside the bundle.
 
constraint	R3.CA	L69.CA	-10	10	20	1.0
constraint	I84.CA	L182.CA	-10	10	20	1.0
constraint	P115.CA	M171.CA	-10	10	20	1.0
constraint	D118.CA	K161.CA	-10	10	20	1.0
constraint	I119.CA	A180.CA	-10	10	20	1.0
constraint	A121.CA	L184.CA	-10	10	20	1.0
constraint	E128.CA	R150.CA	-10	10	20	1.0
constraint	A133.CA	A187.CA	-10	10	20	1.0