For T0198, we had fold-recognition alignments to various all-alpha proteins, but none of them were a convincing model for the whole protein, so we ended up folding this one pretty much from scratch. We ended up with two main hypotheses: an up-down bundle an alpha sandwich Another, slightly different bundle is try8-opt2. It does not break the helices badly, but it packs them poorly, with several of the helices turned so that their hydrophobic sides are exposed.