a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0195 Hypothetical esterase in SMC3-MRPL8 intergenic region, S. cerevisiae
- gi|20547663|ref|XP_166266.1|_3:280 (XM_166266) similar to Esterase D [Homo sapiens]
- gi|544254 sp|P10768|ESTD_HUMAN Esterase D
- gi|4093225|gb|AAC99788.1| (AF112219) esterase D [Homo sapiens]
- gi|13937355|ref|NP_058599.1|_3:280 (NM_016903) esterase 10; esterase D [Mus musculus]
- gi|20876924|ref|XP_122742.1| (XM_122742) esterase 10 [Mus musculus]
- gi|5931565|dbj|BAA84693.1| (AB025408) sid478p [Mus musculus]
- gi|12841131|dbj|BAB25090.1| (AK007527) data source:MGD, source key:MGI:95421, evidence:ISS~esterase 10~putative [Mus musculus]
- gi|12862022|dbj|BAB32330.1| (AK021209) data source:MGD, source key:MGI:95421, evidence:ISS~esterase 10~putative [Mus musculus]
- gi|12846304|dbj|BAB27115.1|_33:310 (AK010683) data source:MGD, source key:MGI:95421, evidence:ISS~esterase 10~putative [Mus musculus]
- gi|12654663|gb|AAH01169.1|AAH01169_3:280 (BC001169) Similar to esterase 10 [Homo sapiens]
- gi|7288152|dbj|BAA92850.1|_3:280 (AB032555) esterase D [Sus scrofa]
- gi|9857260|dbj|BAB11922.1|_3:280 (AB038362) esterase D [Sus scrofa]
- gi|10443892|gb|AAG17630.1|AF254785_1 (AF254785) esterase D [Sus scrofa]
- gi|6322393|ref|NP_012467.1|_1:299 (NC_001142) Hypothetical ORF; Yjl068cp [Saccharomyces cerevisiae]
- gi|731936 sp|P40363|YJG8_YEAST Hypothetical 33.9 kDa esterase in SMC3-MRPL8 intergenic region
- gi|1077819|pir||S50803 hypothetical protein YJL068c - yeast (Saccharomyces cerevisiae)
- gi|498998|emb|CAA84054.1| (Z34288) 39.8% identity in 289 aa overlap with human esterase D [Saccharomyces cerevisiae]
- gi|1008219|emb|CAA89359.1| (Z49343) ORF YJL068c [Saccharomyces cerevisiae]
- gi|16761136|ref|NP_456753.1|_1:276 (NC_003198) putative esterase [Salmonella enterica subsp. enterica serovar Typhi]
- gi|16503434|emb|CAD02576.1| (AL627273) putative esterase [Salmonella enterica subsp. enterica serovar Typhi]
- gi|15598824|ref|NP_252318.1|_5:281 (NC_002516) probable esterase [Pseudomonas aeruginosa]
- gi|11351274|pir||A83191 probable esterase PA3628 [imported] - Pseudomonas aeruginosa (strain PAO1)
- gi|9949787|gb|AAG07016.1|AE004783_1 (AE004783) probable esterase [Pseudomonas aeruginosa]
- gi|15802710|ref|NP_288737.1|_1:276 (NC_002655) putative esterase (EC 3.1.1.-). [Escherichia coli O157:H7 EDL933]
- gi|15832300|ref|NP_311073.1| (NC_002695) putative esterase [Escherichia coli O157:H7]
- gi|12516474|gb|AAG57292.1|AE005447_7 (AE005447) putative esterase (EC 3.1.1.-). [Escherichia coli O157:H7 EDL933]
- gi|13362515|dbj|BAB36469.1| (AP002560) putative esterase [Escherichia coli O157:H7]
- gi|21232816|ref|NP_638733.1|_1:274 (NC_003902) esterase [Xanthomonas campestris pv. campestris str. ATCC 33913]
- gi|21114640|gb|AAM42657.1| (AE012457) esterase [Xanthomonas campestris pv. campestris str. ATCC 33913]
- gi|21241507|ref|NP_641089.1|_1:274 (NC_003919) esterase [Xanthomonas axonopodis pv. citri str. 306]
- gi|21106853|gb|AAM35625.1| (AE011703) esterase [Xanthomonas axonopodis pv. citri str. 306]
- gi|17230300|ref|NP_486848.1|_4:279 (NC_003272) S-formylglutathione hydrolase [Nostoc sp. PCC 7120]
- gi|17131901|dbj|BAB74507.1| (AP003590) S-formylglutathione hydrolase [Nostoc sp. PCC 7120]
- gi|16272149|ref|NP_438352.1|_1:274 (NC_000907) esterase [Haemophilus influenzae Rd]
- gi|1175854 sp|P44556|YAIM_HAEIN Protein HI1084
- gi|1074301|pir||A64145 hypothetical protein HI0184 - Haemophilus influenzae (strain Rd KW20)
- gi|1573140|gb|AAC21853.1| (U32703) esterase [Haemophilus influenzae Rd]
- gi|16130092|ref|NP_416659.1|_1:276 (NC_000913) putative esterase (EC 3.1.1.-). [Escherichia coli K12]
- gi|465595 sp|P33018|YEIG_ECOLI Hypothetical protein yeiG
- gi|7449188|pir||A64984 hypothetical 31.3 kD protein in folE-cirA intergenic region - Escherichia coli (strain K-12)
- gi|405878|gb|AAA60510.1| (U00007) yeiG [Escherichia coli]
- gi|1788477|gb|AAC75215.1| (AE000304) putative esterase (EC 3.1.1.-). [Escherichia coli K12]
- gi|744188|prf||2014253AY esterase [Escherichia coli]
- gi|15677171|ref|NP_274324.1|_1:274 (NC_003112) esterase, putative [Neisseria meningitidis MC58]
- gi|11279783|pir||G81097 esterase, probable NMB1305 [imported] - Neisseria meningitidis (group B strain MD58)
- gi|7226546|gb|AAF41680.1| (AE002479) esterase, putative [Neisseria meningitidis MC58]
- gi|15794413|ref|NP_284235.1|_1:274 (NC_003116) esterase D [Neisseria meningitidis Z2491]
- gi|11279782|pir||C81843 carboxylesterase (EC 3.1.1.1) D NMA1519 [imported] - Neisseria meningitidis (group A strain Z2491)
- gi|7380161|emb|CAB84747.1| (AL162756) esterase D [Neisseria meningitidis Z2491]
- gi|895893|emb|CAA61307.1|_3:285 (X88851) hypothetical esterase [Saccharomyces cerevisiae]
- gi|21295504|gb|EAA07649.1|_47:325 (AAAB01008859) agCP1126 [Anopheles gambiae str. PEST]
- gi|15965144|ref|NP_385497.1|_1:276 (NC_003047) PUTATIVE S-FORMYLGLUTATHIONE HYDROLASE PROTEIN [Sinorhizobium meliloti]
- gi|15074324|emb|CAC45970.1| (AL591787) PUTATIVE S-FORMYLGLUTATHIONE HYDROLASE PROTEIN [Sinorhizobium meliloti]
- gi|15800086|ref|NP_286098.1|_1:275 (NC_002655) putative esterase (EC 3.1.1.1) [Escherichia coli O157:H7 EDL933]
- gi|15829664|ref|NP_308437.1| (NC_002695) putative esterase [Escherichia coli O157:H7]
- gi|12513194|gb|AAG54706.1|AE005215_3 (AE005215) putative esterase (EC 3.1.1.1) [Escherichia coli O157:H7 EDL933]
- gi|13359867|dbj|BAB33833.1| (AP002551) putative esterase [Escherichia coli O157:H7]
- gi|15888800|ref|NP_354481.1|_1:276 (NC_003062) AGR_C_2723p [Agrobacterium tumefaciens] [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|17935376|ref|NP_532166.1| (NC_003304) esterase D [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|15156556|gb|AAK87266.1| (AE008072) AGR_C_2723p [Agrobacterium tumefaciens str. C58 (Cereon)]
- gi|17739899|gb|AAL42482.1| (AE009107) esterase D [Agrobacterium tumefaciens str. C58 (U. Washington)]
- gi|16121774|ref|NP_405087.1|_5:278 (NC_003143) putative esterase [Yersinia pestis]
- gi|22126547|ref|NP_669970.1| (NC_004088) putative esterase [Yersinia pestis KIM]
- gi|15979543|emb|CAC90324.1| (AJ414148) putative esterase [Yersinia pestis]
- gi|21959549|gb|AAM86221.1|AE013869_6 (AE013869) putative esterase [Yersinia pestis KIM]
- gi|17988105|ref|NP_540739.1|_7:282 (NC_003317) S-FORMYLGLUTATHIONE HYDROLASE [Brucella melitensis]
- gi|17983857|gb|AAL53003.1| (AE009614) S-FORMYLGLUTATHIONE HYDROLASE [Brucella melitensis]
- gi|16128340|ref|NP_414889.1|_1:275 (NC_000913) putative esterase (EC 3.1.1.1) [Escherichia coli K12]
- gi|2506603 sp|P51025|YAIM_ECOLI Hypothetical protein yaiM
- gi|7449189|pir||C64763 yaiM protein - Escherichia coli
- gi|1657552|gb|AAB18080.1| (U73857) similar to E. coli yeiG [Escherichia coli]
- gi|1786551|gb|AAC73458.1| (AE000142) putative esterase (EC 3.1.1.1) [Escherichia coli K12]
- gi|21295524|gb|EAA07669.1|_10:286 (AAAB01008859) ebiP2917 [Anopheles gambiae str. PEST]
- gi|87028|pir||A23543_17:295 methylumbelliferyl-acetate deacetylase (EC 3.1.1.56) - human (fragment)
- gi|182265|gb|AAA52408.1| (M13450) esterase D [Homo sapiens]
- gi|21233675|ref|NP_639973.1|_6:280 (NC_003905) esterase [Proteus vulgaris]
- gi|21202859|dbj|BAB93575.1| (AP004237) esterase [Proteus vulgaris]
- gi|15227376|ref|NP_181684.1|_5:282 (NM_129716) putative esterase D [Arabidopsis thaliana]
- gi|7449191|pir||T00809 hypothetical protein T32G6.5 - Arabidopsis thaliana
- gi|2618688|gb|AAB84335.1| (AC002510) putative esterase D [Arabidopsis thaliana]
- gi|14190395|gb|AAK55678.1|AF378875_1 (AF378875) At2g41530/T32G6.5 [Arabidopsis thaliana]
- gi|14994257|gb|AAK73263.1| (AY044322) putative esterase D [Arabidopsis thaliana]
- gi|17386096|gb|AAL38594.1|AF446861_1 (AF446861) At2g41530/T32G6.5 [Arabidopsis thaliana]
- gi|19572942|emb|CAC87877.1| (AJ347732) S-formylglutathione hydrolase [Arabidopsis thaliana]
- gi|7300589|gb|AAF55741.1|_3:282 (AE003728) CG4390 gene product [Drosophila melanogaster]
- gi|21429822|gb|AAM50589.1| (AY118729) GH03475p [Drosophila melanogaster]
- gi|17545323|ref|NP_518725.1|_7:285 (NC_003295) PROBABLE HYDROLASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
- gi|17427615|emb|CAD14134.1| (AL646060) PROBABLE HYDROLASE OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
- gi|13475915|ref|NP_107485.1|_5:280 (NC_002678) esterase [Mesorhizobium loti]
- gi|14026675|dbj|BAB53271.1| (AP003011) esterase [Mesorhizobium loti]
- gi|21593226|gb|AAM65175.1|_2:270 (AY087636) putative esterase D [Arabidopsis thaliana]
- gi|16329755|ref|NP_440483.1|_1:271 (NC_000911) esterase [Synechocystis sp. PCC 6803]
- gi|7449190|pir||S75249 esterase sll0992 - Synechocystis sp. (strain PCC 6803)
- gi|1652240|dbj|BAA17163.1| (D90904) esterase [Synechocystis sp. PCC 6803]
- gi|16263919|ref|NP_436711.1|_1:274 (NC_003078) putative S-formylglutathione hydrolase protein [Sinorhizobium meliloti]
- gi|15140043|emb|CAC48571.1| (AL603642) putative S-formylglutathione hydrolase protein [Sinorhizobium meliloti]
- gi|16126754|ref|NP_421318.1|_3:276 (NC_002696) esterase [Caulobacter crescentus CB15]
- gi|13424072|gb|AAK24486.1| (AE005919) esterase [Caulobacter crescentus CB15]
- gi|2665774|gb|AAC04838.1|_4:277 (AF035558) S-formylglutathione hydrolase [Anabaena azollae]
- gi|1002868|gb|AAC44554.1|_5:274 (U34346) S-formylglutathione hydrolase [Paracoccus denitrificans]
- gi|16765524|ref|NP_461139.1|_1:238 (NC_003197) putative esterase [Salmonella typhimurium LT2]
- gi|16420732|gb|AAL21098.1| (AE008798) putative esterase [Salmonella typhimurium LT2]
- gi|20161330|dbj|BAB90254.1|_14:319 (AP003412) putative esterase D [Oryza sativa (japonica cultivar-group)]
- gi|17510185|ref|NP_493371.1|_4:279 (NM_060970) putative esterase [Caenorhabditis elegans]
- gi|6580309|emb|CAB60384.2| (AL132847) contains similarity to Pfam domain: PF00756 (Putative esterase), Score=191.7, E-value=3.8e-54, N=1~cDNA EST yk83a1.3 comes from this gene~cDNA EST yk83a1.5 comes from this gene~cDNA EST yk312b1.3 comes from this gene~cDNA EST yk312b1.5 comes>
- gi|6580345|emb|CAB63414.1| (AL110500) contains similarity to Pfam domain: PF00756 (Putative esterase), Score=191.7, E-value=3.8e-54, N=1~cDNA EST yk83a1.3 comes from this gene~cDNA EST yk83a1.5 comes from this gene~cDNA EST yk312b1.3 comes from this gene~cDNA EST yk312b1.5 comes>
- gi|6048346|gb|AAF02201.1|AF059739_1_3:248 (AF059739) lipase [Lactococcus lactis subsp. cremoris]
- gi|7453518|gb|AAF62860.1|_3:248 (AF157601) tributyrin esterase [Lactococcus lactis subsp. cremoris]
- gi|15963430|dbj|BAB69464.1| (AB072443) esterase homolog [Lactococcus lactis subsp. lactis]
- gi|22086635|gb|AAM90699.1|AF405559_1_3:248 (AF405559) carboxylesterase [Lactococcus lactis subsp. cremoris]
- gi|15673753|ref|NP_267928.1|_3:248 (NC_002662) lipase [Lactococcus lactis subsp. lactis]
- gi|7453516|gb|AAF62859.1|AF157484_1 (AF157484) tributyrin esterase [Lactococcus lactis subsp. lactis]
- gi|12724794|gb|AAK05869.1|AE006407_5 (AE006407) lipase [Lactococcus lactis subsp. lactis]
- gi|15082066|gb|AAK84012.1|AF393838_1 (AF393838) tributyrin esterase [Lactococcus lactis subsp. lactis]
- gi|21280513|gb|AAM45148.1|AF350244_2_3:248 (AF350244) esterase [Lactococcus lactis]
- gi|11385866|gb|AAG34997.1|AF306495_1_12:259 (AF306495) esterase MesA [Pasteurella multocida]
- gi|15603316|ref|NP_246390.1|_12:259 (NC_002663) XynC [Pasteurella multocida]
- gi|12721830|gb|AAK03535.1| (AE006181) XynC [Pasteurella multocida]
- gi|19746007|ref|NP_607143.1|_5:251 (NC_003485) putative tributyrin esterase [Streptococcus pyogenes MGAS8232]
- gi|21910194|ref|NP_664462.1| (NC_004070) putative tributyrin esterase [Streptococcus pyogenes MGAS315]
- gi|19748171|gb|AAL97642.1| (AE010028) putative tributyrin esterase [Streptococcus pyogenes MGAS8232]
- gi|21904388|gb|AAM79265.1| (AE014150) putative tributyrin esterase [Streptococcus pyogenes MGAS315]
- gi|15675022|ref|NP_269196.1|_5:251 (NC_002737) putative tributyrin esterase [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
- gi|13622172|gb|AAK33917.1| (AE006547) putative tributyrin esterase [Streptococcus pyogenes M1 GAS]
- gi|15900522|ref|NP_345126.1|_4:249 (NC_003028) tributyrin esterase [Streptococcus pneumoniae TIGR4]
- gi|15902583|ref|NP_358133.1| (NC_003098) tributyrin esterase [Streptococcus pneumoniae R6]
- gi|14972089|gb|AAK74766.1| (AE007370) tributyrin esterase [Streptococcus pneumoniae TIGR4]
- gi|15458114|gb|AAK99343.1| (AE008432) tributyrin esterase [Streptococcus pneumoniae R6]
- gi|16801589|ref|NP_471857.1|_4:250 (NC_003212) similar to acetylesterase [Listeria innocua]
- gi|16415049|emb|CAC97754.1| (AL596172) similar to acetylesterase [Listeria innocua]
- gi|16804471|ref|NP_465956.1|_4:250 (NC_003210) similar to acetylesterase [Listeria monocytogenes EGD-e]
- gi|16411921|emb|CAD00511.1| (AL591983) similar to acetylesterase [Listeria monocytogenes]
- gi|408716|gb|AAC42062.1|_536:773 (M76427) dipeptidyl aminopeptidase-related protein [Rattus norvegicus]
- gi|4038348|gb|AAC97365.1|_443:679 (AF092506) dipeptidyl aminopeptidase-like protein 6 [Mus musculus]
- gi|913778|gb|AAB32954.1|_537:773 BSPL=neural membrane CD26 peptidase-like protein [rats, brain, Peptide, 803 aa]
- gi|1092099|prf||2022316A neural membrane CD26 peptidase-like protein [Rattus norvegicus]
- gi|12408298|ref|NP_074041.1|_592:829 (NM_022850) dipeptidylpeptidase 6 [Rattus norvegicus]
- gi|1169415 sp|P46101|DPP6_RAT Dipeptidyl peptidase IV like protein (Dipeptidyl aminopeptidase-related protein) (Dipeptidylpeptidase VI) (DPPX)
- gi|408714|gb|AAC42061.1| (M76426) dipeptidyl aminopeptidase-related protein [Rattus norvegicus]
- gi|4038350|gb|AAC97366.1|_538:774 (AF092507) dipeptidyl aminopeptidase-like protein 6 embryonic isoform [Mus musculus]
- gi|20971310|ref|XP_135560.1|_3:193 (XM_135560) similar to sid478p [Mus musculus]
- gi|284605|pir||A41793_537:773 dipeptidyl aminopeptidase-like protein (EC 3.4.14.-) short form, DPPX-S - bovine
- gi|241658|gb|AAA06685.1| dipeptidyl aminopeptidase-like protein-short form, DPPX-S [cattle, Peptide, 803 aa]
- gi|408720|gb|AAC41623.1| (M76429) dipeptidyl aminopeptidase-related protein [Bos taurus]
- gi|1169413 sp|P42659|DPP6_BOVIN_597:833 Dipeptidyl peptidase IV like protein (Dipeptidyl aminopeptidase-related protein) (Dipeptidylpeptidase VI) (DPPX)
- gi|408718|gb|AAC41622.1| (M76428) dipeptidyl aminopeptidase-related protein [Bos taurus]
- gi|14518327|ref|NP_116810.1|_10:267 (NC_002806) MS122, putative esterase [Microscilla sp. PRE1]
- gi|14484962|gb|AAK62844.1| (AF339846) MS122, putative esterase [Microscilla sp. PRE1]
- gi|15925619|ref|NP_373153.1|_4:246 (NC_002758) hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]
- gi|15928215|ref|NP_375748.1| (NC_002745) hypothetical protein, similar to tributyrin esterase [Staphylococcus aureus subsp. aureus N315]
- gi|21284279|ref|NP_647367.1| (NC_003923) ORFID:MW2550~hypothetical protein, similar to tributyrin esterase [Staphylococcus aureus subsp. aureus MW2]
- gi|13702587|dbj|BAB43727.1| (AP003138) ORFID:SA2422~hypothetical protein, similar to tributyrin esterase [Staphylococcus aureus subsp. aureus N315]
- gi|14248404|dbj|BAB58791.1| (AP003366) hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]
- gi|21205723|dbj|BAB96415.1| (AP004831) ORFID:MW2550~hypothetical protein, similar to tributyrin esterase [Staphylococcus aureus subsp. aureus MW2]
- gi|21224907|ref|NP_630686.1|_49:271 (NC_003888) putative secreted protein [Streptomyces coelicolor A3(2)]
- gi|7479294|pir||T29115 hypothetical protein - Streptomyces coelicolor
- gi|3451438|emb|CAA20497.1| (AL031350) putative secreted protein [Streptomyces coelicolor A3(2)]
- gi|21221823|ref|NP_627602.1|_113:371 (NC_003888) putative membrane protein [Streptomyces coelicolor A3(2)]
- gi|7481015|pir||T36322 probable membrane protein - Streptomyces coelicolor
- gi|4808335|emb|CAB42749.1| (AL049841) putative membrane protein [Streptomyces coelicolor A3(2)]
- gi|20955254|ref|XP_135649.1|_10:148 (XM_135649) similar to esterase 10; esterase D [Mus musculus]
- gi|20961916|ref|XP_125266.1|_10:148 (XM_125266) similar to esterase 10; esterase D [Mus musculus]
- gi|22041021|ref|XP_035312.3|_492:738 (XM_035312) similar to Dipeptidyl peptidase IV like protein (Dipeptidyl aminopeptidase-related protein) (Dipeptidylpeptidase VI) (DPPX) [Homo sapiens]
- gi|7959245|dbj|BAA96016.1|_457:703 (AB040925) KIAA1492 protein [Homo sapiens]
- gi|20971313|ref|XP_135561.1|_3:126 (XM_135561) similar to sid478p [Mus musculus]
- gi|20954222|ref|XP_125258.1|_1:114 (XM_125258) similar to esterase 10; esterase D [Mus musculus]
- gi|6984138|gb|AAF34769.1|AF227624_1_1:129 (AF227624) putative esterase D [Euphorbia esula]
- gi|20987678|gb|AAH29696.1|_88:324 (BC029696) Similar to KIAA1492 protein [Mus musculus]
- gi|3599417|gb|AAC35353.1|_16:212 (AF083393) outer membrane protein adhesin [Capnocytophaga gingivalis]
- gi|16330605|ref|NP_441333.1|_267:398 (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
- gi|7470450|pir||S75452 hypothetical protein slr1506 - Synechocystis sp. (strain PCC 6803)
- gi|1653097|dbj|BAA18013.1| (D90911) ORF_ID:slr1506~unknown protein [Synechocystis sp. PCC 6803]

              10        20        30          40        50        60   
              |         |         |           |         |         |   
   1 MKVVKEFSVCGGRLIKLSHNSNSTKTSMNVNIYLPK.HY.YAQDFPRNKRIPTVFYLSGLTCTP.
   2 LKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPP.KA.------ETGKCPALYWLSGLTCTE.
   3 LKQISSNRCFGGLQKVFEHSSVELKCKMRFAVYLPP.QA.------ESGKCPALYWLSGLTCTE.
   4 LKQISSNRCFGGLQKVFEHSSVELKCKMRFAVYLPP.QA.------ESGKCPALYWLSGLTCTE.
   5 LKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPP.KA.------ETGKCPALYWLSGLTCTE.
   6 LKQLSSNKCFGGLQKVFEHDSVELKCKMKFAIYLPP.KA.------ETGKCPALYWLSGLTCTE.
   7 LKQLSSNKCFGGLQKVFEHDSVELKCKMKFAIYLPP.KA.------ETGKCPALYWLSGLTCTE.
   8 MKVVKEFSVCGGRLIKLSHNSNSTKTSMNVNIYLPK.HY.YAQDFPRNKRIPTVFYLSGLTCTP.
   9 MEMLEEHRCFGGWQQRWRHHAATLNCAMTFSIFLPP.TQ.------DNEPPPVLYWLSGLTCND.
  10 LELIGSQKTFGGWHQRYRHFSRTLNCEMVFAIYLPP.QA.-----EPEAALPALYWLSGLTCTD.
  11 MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPP.PR.------DHTPPPVLYWLSGLTCND.
  12 MERIEHRACFGGWQDVYRHHSTSLGCAMQVGVYLPP.QA.------ADGPLPVLYWLSGLTCTE.
  13 MERIEHRACFGGWQDVYRHQSHTLNCSMQVGVYLPP.QA.------ADGPLPVLYWLSGLTCTE.
  14 LKLISEYQSFGGKLGFYSHPSSTCNGEMRFAVYQPP.QA.------AEKPLPVLYFLSGLTCTE.
  15 MKLIEQHQIFGGSQQVWAHNAQTLQCEMKFAVYLPN.NP.------ENRPLGVIYWLSGLTCTE.
  16 MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPP.PR.------DHTPPPVLYWLSGLTCND.
  17 MKLIEQHQIFGGSQQVWAHHAQTLQCEMKFAVYLPN.NP.------ENRPLGVIYWLSGLTCTE.
  18 MKLIEQHQIFGGSQQVWAHHAQTLQCEMKFAVYLPN.NP.------ENRPLGVIYWLSGLTCTE.
  19 ----------------LSHNSNSTKTSMNVNIYLPK.HY.YAQDFPRNKRIPTVFYLSGLTCTP.
  20 ISLISSTKCFGGLQKIYSHQSKELACEMKFAVFLPA.AA.------EDRRLPVLYWLSGLTCNE.
  21 MKVISQNTAFGGMQGVYAHDSTACKGEMTFAVFVPP.QA.------ITEPRPVLWYLSGLTCTH.
  22 MELIEKHASFGGWQNVYRHYSASLKCEMNVGVYLPP.KA.------AGEKLPVLYWLSGLTCNE.
  23 MNIISQNTAFGGMQGVFSHQSETLKSEMTFAVYVPP.KA.------IHEPCPVVWYLSGLTCTH.
  24 LELLEEHRMFGCWQQRYRHAASSLNCHMTFSIYLPP.PR.------DDNPPPVLYWLSGLTCND.
  25 METISTARCFDGTQGVYRHKSEACQCDMTFALFLPP.QA.------KDGPVPVLWYLSGLTCTH.
  26 MELIEKHVSFGGWQNMYRHYSQSLKCEMNVGVYLPP.KA.------ANEKLPVLYWLSGLTCNE.
  27 ISLISSTKCFGGLQKIYSHQSKELACEMKFAVFLPA.AA.------EDRRLPVLYWLSGLTCNE.
  28 LKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPP.KA.------ETGKCPACIGSPGLTCTE.
  29 MELIEQHASAGGWQNVYRHNSQTLNCEMNFGVYLPP.KA.------ATEKLPVLYWLSGLTCTE.
  30 LSEIGSTKMFDGYNKRYKHFSETLGCSMTFSIYFPP.SA.-----SSSHKSPVLYWLSGLTCTD.
  31 LEQLSANKCFEGEQRVYRHRSDTLKCDMTFGVFLPP.AA.-----LEGKPCPVLFFLSGLTCTH.
  32 LELLSEHACFGGVQRFYRHASAAIGLPMRFSVYLPP.QA.-----LAGERCPALVYLAGLTCTE.
  33 MKTISSARSHGGVQGVYSHASDACACDMVFAVFVPP.QA.------REKPCPVVWYLSGLTCTH.
  34 ---------FDGYNKRYKHFSETLGCSMTFSIYFPP.SA.-----SSSHKSPVLYWLSGLTCTD.
  35 MERLEHHASFGGWQSVYSHHSAVLNCTMNVGVYLPP.QA.------TNQHCPVLYWLSGLTCTE.
  36 MELVTQSQCFGGTQSVYRHASEVCGVEMTFGLYMPP.QA.------RTRSVPLLWYLSGLTCTH.
  37 VETLSTHRVHGGTLRYCRHDSTSTGTPMKFTVWIPD.GQ.--------GPFPYLVWLSGLTCTE.
  38 INLVSEYKCFHGKVGFYSHFSTTCNREMRFAVYQPP.QA.------TQKPIPVLYFLSGLTCRE.
  39 YETVSENRSFGGIQGVYRHQSQATGTPMTFAIYLPP.DA.------RHGKVPVLWYLSGLTCTH.
  40 MEMLEEHRCFGGWQQRWRHHAATLNCAMTFSIFLPP.TQ.------DNEPPPVLYWLSGLTCND.
  41 LEQMSRTKMFGGHNLRFRHHSATLGCPMTFSVFLPP.SP.-------ASDLPVLYWLSGLTCND.
  42 -TLVSSNRSFKGRQFVYKHASSTTQCEMTFGVYIPD.HK.------PDEKLPALFYLSGLTCTH.
  43 -------------VINIEYYSEVLGMNRKVNVIYPE.SS.KVEDF-SQTHIPVLYLLHGMSGNE.
  44 -------------VINIEYYSEVLGMNRKVNVIYPE.SS.KVEDF-SNTEIPVLYLLHGMSGNE.
  45 -------------VINIEYYSEVLGMNRKVNVIYPE.SS.KVEDF-SNTEIPVLYLLHGMSGNE.
  46 -------------VINIEYYSEVLGMNRKVNVIYPE.SS.KVEDF-TQTDIPVLYLLHGMSGNE.
  47 -------------VINIEYYSEVLGMNRKVNGIYPE.SS.KVEDF-SNTEIPVLYLLHGMSGNE.
  48 LGLCYSVSAVAFSEKNVEVYSQAMNKNIPVTIVLPE.GY.-----ASSNKYSTIYTLHGWSGNN.
  49 LGLCYSVSAVAFSEKNVEVYSQAMNKNIPVTIVLPE.GY.-----ASSNKYSTIYTLHGWSGNN.
  50 ---------------AIEYHSVVLGMERKVNVIYPD.QSeIPKKDQGDKDIPVLYLLHGMGGNE.
  51 ---------------AIEYHSVVLGMERKVNVIYPD.QSeIPKKDQGDKDIPVLYLLHGMGGNE.
  52 --------------MKIEYYSQVLDMEWGVNVLYPD.AN.RVEEP-ECEDIPVLYLLHGMSGNH.
  53 --------------LELNFKSECLAMQTSVTVILPE.TE.TLYHG-SIPKYKTLYILHGLSNNH.
  54 --------------LELNFKSVCLAMQTSVTVILPE.TD.ALYHG-SIPKYKTLYILHGLSNNH.
  55 -------------------KIEVEDYSLPMQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQs
  56 --------------------IEVEDYSLPMQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQs
  57 --------------------IEVEDYSLPMQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQs
  58 -------------------KIEVEDYSLPMQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQs
  59 --------------------IEVEDYSLPMQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQs
  60 LKEISRNRCFGGLQKFFEHSSVELKCKMKFAVYLPP.QA.------ESGKCPALYWLSGLTYTE.
  61 --------------------IETDDYNLPIQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQ.
  62 --------------------IETDDYNLPIQILKPA.TF.-----TDTAHYPLLLVVDGTPGSQ.
  63 --ELSNPAFEMDGLRFITIKTPHLKGRGDICVFVPK.GE.------DHQSLPVVTLLHGVYGSA.
  64 --------------ISLNYHSPTIGMHQNLTVILPEdQS.FFNNDITAKPLKTLMLLHGLSSDE.
  65 AEVVAVTRVADRQVDLTVRSTALGGRTVEVRLLTPD.GW.NPHDRRHRQHWPTLWLLHGCCGDY.
  66 ---------VSGRVEEIRVVGRTSRIASPAYVYLPP.EY.-FQTRHRGRTFPAAVVLTGYPGTA.
  67 ------------------------------------.--.------------------------.
  68 ------------------------------------.--.------------------------.
  69 ------------------------DYELPLQLSLPK.DF.-----M------------------.
  70 ------------------------DYELPLQLSLPK.DF.-----M------------------.
  71 LKEISRNRCFGGLQKFFEHSSVELKCKMKFAVYLPP.QA.------ESGKCPALYWLSGLTYTE.
  72 ---------------------------MKFAVYLPP.QA.------ESGKCPALYWLSGLTCTE.
  73 ------------------------------------.--.------------------------.
  74 ----------------------------------PK.DF.------------------------.
  75 --------------------------------IKPS.DF.-----NENKKYPLLMFQYSGPGSQ.
  76 ------------------LNDQSRNRRFYVDVYRPQ.RW.------KEGKTPVLVFSHGLASRP.


                   70                 80         90              100   
                   |                  |          |                |   
   1 .DNA..SEK....AFW....QFQADKYG.....FAIVFPDT.SPR.....GDEVANDP..EGSWD
   2 .QNF..ISK....SGY....HQSASEHG.....LVVIAPDT.SPR.....GCNIKGE-..DESWD
   3 .QNF..ISK....SGY....QQAASEHG.....LVVIAPDT.SPR.....GCNIKGE-..DDSWD
   4 .QNF..ISK....SGY....QQAASEHG.....LVVIAPDT.SPR.....GCNIKGE-..DDSWD
   5 .QNF..ISK....SGY....HQSASEHG.....LVVIAPDT.SPR.....GCNIKGE-..DESWD
   6 .QNF..ITK....SGY....HQAASEHG.....LVVIAPDT.SPR.....GCNIKGE-..DESWD
   7 .QNF..ITK....SGY....HQAASEHG.....LVVIAPDT.SPR.....GCNIKGE-..DESWD
   8 .DNA..SEK....AFW....QFQADKYG.....FAIVFPDT.SPR.....GDEVANDP..EGSWD
   9 .ENF..TTK....AGA....QRIAAELG.....IVLVMPDT.SPR.....GEQVADD-..-SGYD
  10 .ENF..MQK....AGA....QRVAAELG.....LVLVAPDT.SPR.....GSGVPGDP..DGAWD
  11 .ENF..TTK....AGA....QRVAAELG.....IVLVMPDT.SPR.....GEKVAND-..-DGYD
  12 .QNF..ISK....AGA....QRYAAEHG.....VILVAPDT.SPR.....GDDVADA-..-EGYD
  13 .QNF..ISK....AGA....QRYAAEHG.....VILIAPDT.SPR.....GEDVADA-..-DGYD
  14 .ENF..MAK....AGA....QRYAAEYG.....LILVAPDT.SPR.....NTGIAGE-..DDEWD
  15 .QNF..ITK....SGF....QRYAAEHQ.....VIVVAPDT.SPR.....GEQVPND-..-AAYD
  16 .ENF..TTK....AGA....QRVAAELG.....IVLVMPDT.SPR.....GEKVAND-..-DGYD
  17 .QNF..ITK....SGF....QRYAAEHQ.....VIVVAPDT.SPR.....GEQVPND-..-DAYD
  18 .QNF..ITK....SGF....QRYAAEHQ.....VIVVASDT.SPR.....GEQVPND-..-DAYD
  19 .DNA..SEK....AFW....QFQADKYG.....FAIVFPDT.SPR.....GDEVANDP..EGSWD
  20 .TNF..IQK....AGA....QRYATEHN.....LIVVCPDT.SPR.....NVNLPGE-..DDSWD
  21 .ANV..MEK....GEY....RRMASELG.....LIIVCPDT.SPR.....GADVPDEL..-TNWQ
  22 .QNF..ITK....SGV....QRYAAEHN.....IIVVAPDT.SPR.....GSHVADA-..-DRYD
  23 .ANV..MEK....GEY....RRMASELG.....LVVVCPDT.SPR.....GNDVPDEL..-TNWQ
  24 .ENF..TLK....AGA....QRVAAELG.....LVLVMPDT.SPR.....GDNVPND-..-DSYD
  25 .QNV..MDK....GEY....RQLASELG.....IAVICPDT.SPR.....GDSIADEP..-DNWQ
  26 .QNF..ITK....SGM....QRYAAEHN.....IIVVAPDT.SPR.....GSHVADA-..-DRYD
  27 .TNF..IQK....AGA....QRYATEHN.....LIVVCPDT.SPR.....NVNLPGE-..DDSWD
  28 .PKF..YHQ....NLV....IISLLQNH.....LSCCHCSRySPR.....ACNIKGE-..DESWD
  29 .QNF..ITK....SGM....QHYAARNN.....IIVVVPDT.SPR.....GEHVADA-..-DSYD
  30 .ENF..IIK....SGA....QRAASTHG.....IALVAPDT.SPR.....GLNVEGE-..ADSYD
  31 .ENF..IQK....SGF....QQHAARHN.....LIVVNPDT.SPR.....GVEIAGQ-..DDAYD
  32 .ETF..PIK....AGA....QRIAAREG.....LILIAPDT.SPR.....DANVPGE-..ADSWD
  33 .ANV..MDK....GEY....RRMAAELG.....LIVVCPDT.SPR.....GGDIPDE-..KDNWQ
  34 .ENF..IIK....SGA....QRAASTHG.....IALVAPDT.SPR.....GLNVEGE-..ADSYD
  35 .QNA..ITK....SGL....QQHAAKHG.....LIMVTPDT.SPR.....GEGVTDS-..-EDYD
  36 .ENA..MIK....AGL....QRHAAEQG.....LALVFPDT.SPR.....GEGVADD-..-EAYD
  37 .DNF..TVK....SGV....YEHAARHG.....IAIVAPDT.SPR.....GEGVADD-..-PAYD
  38 .DNF..MIK....AGA....QQ------.....---VAPDT.SPR.....NTGIAGE-..NDQWD
  39 .ENA..MTK....AGA....QEWAAEYG.....IAVIFPDT.SPR.....GEGVAND-..-ETYD
  40 .ENF..TTK....AGA....QRIAAELG.....IVLVMPDT.SPR.....GEQVADD-..-SGYD
  41 .ENF..VTK....AGA....QRAAAAHG.....IALVAPDT.SPRm28lr-FELLEDPlrEILYQ
  42 .ANF..MEK....SGF....QQFASKHR.....LVVVHPDT.SPR.....GVDVDGD-..SESWD
  43 .NSW..MIR....SGI....ERLIRHTN.....LAIVMPST.D--.....--------..-----
  44 .NSW..MIR....SGI....ERLIRHTN.....LAIVMPST.D--.....--------..-----
  45 .NSW..MIR....SGI....ERLIRHTN.....LAIVMPST.D--.....--------..-----
  46 .NSW..IIR....SGI....ERLIRHTN.....LAIVMPST.D--.....--------..-----
  47 .NSW..MIR....SGI....ERLIRHTN.....LAIVMPST.D--.....--------..-----
  48 .RNY..PEK....TGL....GELADQYN.....VIYVSPD-.---.....--------..-----
  49 .RNY..PEK....TGL....GELADKYN.....VIYVSPD-.---.....--------..-----
  50 .NSW..QKR....TAI....ERLLRHTN.....LIVVMPST.D--.....--------..-----
  51 .NSW..QKR....TAI....ERLLRHTN.....LIVVMPST.D--.....--------..-----
  52 .NSW..LKR....TNV....ERLLRGTN.....LIVVMPNT.S--.....--------..-----
  53 .TTY..VRN....TNI....ERYATEKG.....LAVIMPAA.D--.....--------..-----
  54 .TTY..VRN....TNI....ERYATEKG.....LAVIMPAA.D--.....--------..-----
  55 vSER..FEV....TWE....TVLVSSHG.....AVVVKCD-.---.....--------..-----
  56 vTER..FEV....TWE....TVLVSSHG.....AVVVKCD-.---.....--------..-----
  57 vSER..FEV....TWE....TVLVSSHG.....AVVVKCD-.---.....--------..-----
  58 vSER..FEV....TWE....TVLVSSHG.....AVVVKCD-.---.....--------..-----
  59 vTER..FEV....TWE....TVLVSSHG.....AVVVKCD-.---.....--------..-----
  60 .QNY..ISK....SGY....QQAASEPG.....LVVIAPDT.SPR.....GCNIKGE-..DDSWD
  61 .SVAekFAV....TWE....TVMVSSHG.....AVVVKCD-.---.....--------..-----
  62 .SVAekFAV....TWE....TVMVSSHG.....AVVVKCD-.---.....--------..-----
  63 .WVW..PFL....GNAhgitQRLIDQKKipp..MVLVMPS-.---.....--------..DGLW-
  64 .TTY..MRY....TSI....ERYANEHK.....LAVIMPNV.D--.....--------..-----
  65 .TSW..TSM....TDV....AETESLRD.....VLVVMPE-.---.....--------..-----
  66 .EAL..VEK....LHY....PRTALELAka9miLVMLRPTVaPPR.....DTECVDVP..-----
  67 .---..---....---....--------.....--------.---.....--------..-----
  68 .---..---....---....--------.....--------.---.....--------..-----
  69 .---..---....---....--DRNQYA.....LLLIM-DE.EPG.....GQLVTDKF..HIDWD
  70 .---..---....---....--DRNQYA.....LLLIM-DE.EPG.....GQLVTDKF..HIDWD
  71 .QNY..ISK....SGY....QQAASEPG.....LVVIAPDT.SPR.....GCNIKGE-..DDSWD
  72 .QNF..ISK....SGY....QQAASEPG.....LVVIAPDT.SPR.....GCNIKGE-..DDSWD
  73 .---..---....---....--------.....--------.---.....--------..-----
  74 .---..MEK....---....----NQYA.....LLLIM-DE.EPG.....GQMVTDKF..HVDWD
  75 .QVH..NSFsgfdTFW....YYMLAQKG.....YIVLCVD-.---.....--------..-----
  76 .EDF..---....DNA....AEKMASYG.....FVVALPQ-.HPG.....SDILQAQ-..-ALLN


               110        120       130        140       150           
                |          |         |          |         |           
   1 F.....GQGAGFY.LNATQEPYAQHYQMYDYIHKELP.QTLDSHFNKNGDVKLDFL.....DNVA
   2 F.....GTGAGFY.VDATEDPWKTNYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
   3 F.....GTGAGFY.VNATEDPWKANYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
   4 F.....GTGAGFY.VNATEDPWKANYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
   5 F.....GTGAGFY.VDATEDPWKTNYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
   6 F.....GTGAGFY.LDATEDPWKTNYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
   7 F.....GTGAGFY.LDATEDPWKTNYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
   8 F.....GQGAGFY.LNATQEPYAQHYQMYDYIHKELP.QTLDSHFNKNGDVKLDFL.....DNVA
   9 L.....GHGAGFY.LNATQPPWASHYRMYDYLRDELP.ALIQTQFNVS--------.....DRCA
  10 F.....GLGAGFY.LNATQEPWAAHYRMHDYVVHELP.ALIEAHFPVS--------.....RRRG
  11 L.....GQGAGFY.LNATQPPWATHYRMYDYLRDELP.ALVQSQFNVS--------.....DRCA
  12 I.....GKGAGFY.VDATEQPWAAHYRMYDYVVNELP.ALIEASFATT--------.....GVRA
  13 I.....GKGAGFY.VDATQAPWAAHYRMYDYVVNELP.ALIEATFATT--------.....GARA
  14 F.....GTGAGFY.VDATEKPWRSHYQMYSYIVQELP.ALIAANFPIQA-------.....EKQG
  15 L.....GQGAGFY.LNATEQPWATNYQMYDYILNELP.DLIEANFPTN--------.....GKRS
  16 L.....GQGAGFY.LNATQPPWATHYRMYDYLRDELP.ALVQSQFNVS--------.....DRCA
  17 L.....GQSAGFY.LNATEQPWAANYQMYDYILNELP.RLIEKHFPTN--------.....GKRS
  18 L.....GQGAGFY.LNATEQPWAANYQMYDYILNELP.RLIEKHFPTN--------.....GKRS
  19 F.....GQGAGFY.LNATQEPYAQHYQMYDYIHKELP.QTLDSHFNKNGDVKLDFL.....DNVA
  20 F.....GSGAGFY.VDATQEPWCKHYRMFSYVTQELI.ELINGNFPTVA-------.....NKMS
  21 M.....GKGAGFY.LDATEKPWAEHYRMYSYITEELP.ALVGQHFRVDM-------.....GRQG
  22 L.....GQGAGFY.LNATQAPWNEHYKMYDYIRNELP.DLVMNHFPAT--------.....AKKS
  23 M.....GKGAGFY.LDATEEPWSEHYQMYSYVTEELP.ALIGQHFRADM-------.....SRQS
  24 L.....GQGAGFY.LNATQEPWSDHFQMYDYISQELP.SLIRQHFSVS--------.....ERQS
  25 F.....GKGAGFY.VDAMQAPFAQNYRMYSYITQELS.ALVARQFPLDM-------.....ERQA
  26 L.....GQGAGFY.LNATQAPWNEHYKMYDYIRNELP.DLVMHHFPAT--------.....AKKS
  27 F.....GSGAGFY.VDATQEPWCKHYRMFSYVTQELI.ELINGNFPTVA-------.....NKMS
  28 F.....ATGRGFY.VDATEDPWKTNYRMYSYVTEELP.QLINANFPVDP-------.....QRMS
  29 L.....GQGAGFY.LNATEHPWNTHYRMYDYILHELP.DVVMEHLPVT--------.....SRKS
  30 F.....GVGAGFY.LNATQEKW-KNWRMYDYVVKELP.KLLSENFSQLDT------.....TKAS
  31 F.....GSGAGFY.VDAKEEPWSKHYKMYSYVTQELV.DVVNANLPVVP-------.....GKRG
  32 F.....GVGAGFY.LDATQAPWRERYRMETYIVEELY.HIARVAFPVAA-------.....GRVG
  33 F.....GSGAGFY.LDATQAPYATNYRMYSYVTEELP.ALIAKVFPADM-------.....TRQA
  34 F.....GVGAGFY.LNATQEKW-KNWRMYDYVVKELP.KLLSENFSQLDT------.....TKAS
  35 L.....GMGAGFY.LNATQPPWAAHYQMHDYIVQELP.TWIEANFAAT--------.....DARS
  36 L.....GQGAGFY.VNATQKPWSPHYRMYDYIVTELP.ALLQEQLPLN--------.....GVNG
  37 L.....GQGAGFY.VDATQAPWAPHFMMHSYVTGDLL.AAVEGAFPLDG-------.....ARKG
  38 I.....GTGAGFYgVDAIEEPWRSHYQMYSYIIQELP.TVINTKFPTEP-------.....NQTS
  39 L.....GQGAGFY.VDATEAPWAPHFRMWHYVTHELP.ELVFNNFPLDR-------.....EAQG
  40 L.....GHGAGFY.LNATQPPWASHYRMYDYLRDELP.ALIQTQFNVS--------.....DRCA
  41 I.....AVSAGFY.LNATNEKW-KNWRMYDYVVKELP.KVLSDNFEQLNT------.....SRAS
  42 F.....GKGAGFY.VNATVEKWAKNYRMYDYIVKELLeEVVPSVAPIDL-------.....AKIG
  43 -.....---LGFY.VNTT-----YGMNYFDAIALELP.KVINNFFPNLSTKR----.....EKNF
  44 -.....---LGFY.VNTT-----YGMNYFDAIALELP.KVIHNFFPNLSTKK----.....EKNF
  45 -.....---LGFY.VNTT-----YGMNYFDAIALELP.KVIHNFFPNLSTKK----.....EKNF
  46 -.....---LGFY.VNTT-----YGMNYFDAIAHELP.KVINNFFPNLSTKR----.....EKNF
  47 -.....---LGFY.VNTT-----YGMNYFDAIALELP.KVIHNFFPNLSTKK----.....EKNF
  48 -.....GNYDSWY.VDSE---LKKDSKYYTFVAKELV.DYVDKHYATHTDK-----.....TQRA
  49 -.....GNYDSWY.VDSE---LKKESKYYTFVSKELV.DYVDKHYATHTDK-----.....TQRA
  50 -.....---LGWY.TDTA-----YGLNYYRALSQELP.QVLAAFFPNMTQKR----.....EKTF
  51 -.....---LGWY.TDTA-----YGLNYYRALSQELP.QVLAAFFPNMTQKR----.....EKTF
  52 -.....---NGWY.TDTQ-----YGFDYYTALAEELP.QVLKRFFPNMTSKR----.....EKTF
  53 -.....---HSFY.SNMV-----HGRDFFQFVSTELP.HVMKNWFPLSDKK-----.....EDTF
  54 -.....---HSFY.SNMV-----HGRDFFEFVSTELP.HVMKNWFPLSDKK-----.....EDTF
  55 -.....GRGSGF-.---------QGTK----LLHEVR.RRLGFLEEKDQMEAVRTMlk8dkTRVA
  56 -.....GRGSGF-.---------QGTK----LLQEVR.RRLGFLEEKDQMEAVRTMlk8dkTRVA
  57 -.....GRGSGF-.---------QGTK----LLHEVR.RRLGFLEEKDQMEAVRTMlk8dkTRVA
  58 -.....GRGSGF-.---------QGTK----LLHEVR.RRLGFLEEKDQMEAVRTMlk8dkTRVA
  59 -.....GRGSGF-.---------QGTK----LLQEVR.RRLGFLEEKDQMEAVRTMlk8dkTRVA
  60 F.....GTGGGFY.VNATEDPWKANYRMYSYVTEELP.QLINANFPVDPQRMVYFW.....SLHG
  61 -.....GRGSGF-.---------QGTR----LLHEVR.RRLGSLEEKDQMEAVRVMlk8dkTRVA
  62 -.....GRGSGF-.---------QGTR----LLHEVR.RRLGSLEEKDQMEAVRVMlk8dkTRVA
  63 -.....GDGSGYM.NH-------DGKNFEKWIAEDVP.DAVFENIPEVSEE-----.....SIHF
  64 -.....---HSAY.ANMA-----YGHSYYDYIL-EVY.DYVHQIFPLSKKR-----.....DDNF
  65 -.....AGWNGWY.SDWWNHGQGGDPAWETFHTKELR.HLLERDWGAG--------.....SNRV
  66 -.....-------.---------GGPQTETFFAKDLP.QAVSTHYRVAKGP-----.....RSWG
  67 -.....-------.-----------------------.------------------.....-GWS
  68 -.....-------.-----------------------.------------------.....-GWS
  69 Sv14fdGRGSGF-.---------QGLK----ILQEIH.RRLGSVEVKDQITAVKFLlk8dsKRLS
  70 Sv14fdGRGSGF-.---------QGLK----ILQEIH.RRLGSVEVKDQITAVKFLlk8dsKRLS
  71 F.....GTGGGFY.VNATEDPWKANYRMYSYVTH---.------------------.....----
  72 F.....GTGAGFY.VNATEDPWKANYRMYSYVTEELP.QLINANFPVDPQRM----.....----
  73 -.....-------.-----------------------.------------------.....----
  74 Sv14fdGRGSGF-.---------QGLK----VLQEIH.RRIGSVEAKDQVAAVKYLlk8dsKRLS
  75 -.....GRGTGYK.GAAFKKCTYKQLGKY-----ELE.DQVEAAKIVGNYKYIDK-.....DRIG
  76 R.....TSRQGYY.PTEF----IDRPKDISYVIDELE.RRNASEFGDRLNL-----.....TQVG


       160       170         180       190            200           210
        |         |           |         |              |             |
   1 ITGHSMGGYGAICG..YLKGYSGKRYKSCSAFAPIV...NPSNV..PWGQKAF...KGYLG.EEK
   2 IFGHSMGGHGALIC..ALKN--PGKYKSVSAFAPIC...NPVLC..PWGKKAF...SGYLG.TDQ
   3 IFGHSMGGHGALIC..ALKN--PGKYRSVSAFAPIC...NPVLC..SWGKKAF...SGYLG.PDE
   4 IFGHSMGGHGALIC..ALKN--PGKYRSVSAFAPIC...NPVLC..SWGKKAF...SGYLG.PDE
   5 IFGHSMGGHGALIC..ALKN--PGKYKSVSAFAPIC...NPVLC..PWGKKAF...SGYLG.TDQ
   6 IFGHSMGGHGALIC..TLKN--PGKYKSVSAFAPIC...NPVLC..PWGKKAF...SGYLG.TDG
   7 IFGHSMGGHGALIC..TLKN--PGKYKSVSAFAPIC...NPVLC..PWGKKAF...SGYLG.TDE
   8 ITGHSMGGYGAICG..YLKGYSGKRYKSCSAFAPIV...NPSNV..PWGQKAF...KGYLG.EEK
   9 ISGHSMGGHGALIM..ALKN--PGKYTSISAFAPIV...NPSRV..PWGIKAL...TAYLG.EDE
  10 ISGHSMGGHGALVC..ALRN--PGRYLSLSAFAPIC...HPSDC..PWGQKAF...SRYLG.EDP
  11 ISGHSMGGHGALIM..ALKN--PGKYTSVSAFAPIV...NPCSV..PWGIKAF...SRYLG.EDK
  12 ISGHSMGGHGALTI..ALKN--PGRYRSVSAFSPIV...APSQV..PWGEKAF...GQYLG.DDR
  13 ISGHSMGGHGALTI..ALKN--PGRYRSVSAFSPIV...APSQV..PWGEKAF...GQYLG.NDR
  14 IFGHSMGGHGALVC..ALRN--PHIFKSVSAFAPIV...TPMGC..PWGQKAF...SRYLG.NNQ
  15 IMGHSMGGHGALVL..ALRN--RERYQSVSAFSPIL...SPSLV..PWGEKAF...SAYLG.EDR
  16 ISGHSMGGHGALIM..ALKN--PGKYTSVSAFAPIV...NPCSV..PWGIKAF...SSYLG.EDK
  17 IMGHSMGGHGALVL..ALRN--QERYQSVSAFSPIL...SPSLV..PWGEKAF...TAYLG.KDR
  18 IMGHSMGGHGALVL..ALRN--QERYQSVSAFSPIL...SPSLV..PWGEKAF...TAYLG.KDR
  19 ITGHSMGGYGAICG..YLKGYSGKRYKSCSAFAPIV...NPSNV..PWGQKAF...KGYLG.EEK
  20 IAGHSMGGHGALIC..ALKN--PGLYKSVSAFAPIS...NPTRC..PWGEKAF...GGYLG.VDS
  21 IFGHSMGGHGAMTV..ALKH--PERFKSCSAFAPIV...APSSA..DWSVGAF...EKYLG.PDK
  22 ISGHSMGGLGALVL..ALRN--PDEYVSVSAFSPIV...SPSQV..PWGQQAF...AAYLG.ENK
  23 IFGHSMGGHGAMTI..ALKN--PERFKSCSAFAPIV...APSSA..DWSEPAL...EKYLG.ADR
  24 ISGHSMGGHGALML..ALRN--PQQYQSVSAFAPIV...NPCQV..PWGRKAF...TAYLG.SDE
  25 ITGHSMGGHGALTI..ALKN--PDRFKSVSAFAPIV...QPSTA..GWSRPAL...EKYLG.PDE
  26 ISGHSMGGLGALVL..ALRN--PDEYVSVSAFSPIV...SPSQV..PWGQQAF...AAYLA.ENK
  27 IAGHSMGGHGALIC..ALKN--PGLYKSVSAFAPIS...NPTRC..PWGEKAF...GGYLG.VDS
  28 IFGHSMGGHGALIC..ALKN--PGKYKSVSAFAPIC...NPVLC..PWGKKAF...SGYLG.TDQ
  29 ISGHSMGGLGALVL..SLRN--PDEYVSVSAFSPIV...SPSQV..PWGQQAF...TAYLG.ENK
  30 ISGHSMGGHGALTI..YLRN--LDKYKSVSAFAPIT...NPINC..AWGQKAF...TNYLG.DNK
  31 IFGHSMGGHGALIC..ALKN--PGLYQSVSAFAPIA...NPTEC..PWGKKAF...AGYLG.SNP
  32 IFGHSMGGHGALTL..ALRH--RERFASVSAFAPIA...HPSAC..PWGVKAF...TGYLG.EDR
  33 IFGHSMGGHGALTI..ALKN--PERFKSCSAFAPIV...QPSTA..GWSRPAL...EKYLG.ADE
  34 ISGHSMGGHGALTI..YLRN--LDKYKSVSAFAPIT...NPINC..AWGQKAF...TNYLG.DNK
  35 IFGHSMGGHGALVI..ALRN--PGRYRSVSTFSPIV...APTQV..PWGQKAF...QAYLG.DNQ
  36 ITGHSMGGHGALTI..AFRN--PELFRSVSAFAPIV...NPTRS..DWGRKQF...SAYLG.DDE
  37 IFGHSMGGHGALTI..ALKH--PELFKSVSAFSPIV...SPLNC..PWGDKAL...TAYLG.PDR
  38 IFGHSMGGDGALIC..AMKN--PQLYKSVSAFAPIV...APMQC..SRGQKAFnpfNLYLG.NNQ
  39 ITGHSMGGHGALTI..AMTF--PERYRSVSAFAPIA...HPSES..DWGRKQF...AAYLG.DDK
  40 ISGHSMGGHGALIM..ALKN--PGKYTSVSAFAPIV...NPSRV..PWGIKAL...TAYLG.EDE
  41 IFGHSMGGHGALTI..YLKN--TDKYKSVSAFSPVV...NPINC..PWGQKAF...SNYLG.PAK
  42 IFGHSMGGHGALTI..GLRN--SSKFQSISAFAPIC...NPITV..PWGQKAL...TGYLGdEDK
  43 IAGLSMGGYGAYRL..ALGT---DYFSYAASLSGVL...TFDGM..EENFKEN...PAYWG.GIF
  44 IAGLSMGGYGAYRL..ALGT---DHFSYAASLSGVL...TFDGM..EENFKEN...PAYWG.GIF
  45 IAGLSMGGYGAYRL..ALGT---DHFSYAASLSGVL...TFDGM..EENFKEN...PAYWG.GIF
  46 IAGLSMGGYGAYRL..ALGT---DYFSYAASLSGVL...TFDGM..EENFKEN...PAYWG.GIF
  47 IAGLSMGGYGAYRL..ALGT---DHFSYAASLSGVL...TFDGM..EENFKEN...PAYWG.GIF
  48 ITGLSMGGFGALYI..GIKN--QDRFGNIGSMSGGV...NIEQYknNWGISAV...-----.-VN
  49 ITGLSMGGFGALYI..GIKN--QDRFGNIGSMSGGV...NIEQYknNWGISAV...-----.-VN
  50 VAGLSMGGYGAFKW..ALKS---NRFSYAASFSGAL...DFSPE..TLLEGNLge.LAYWQ.GVF
  51 VAGLSMGGYGAFKW..ALKS---NRFSYAASFSGAL...DFSPE..TLLEGKLge.LAYWQ.GVF
  52 IAGLSMGGYGCFKL..ALTT---NRFSHAASFSGAL...SFQNF..SPESQNLgs.PAYWR.GVF
  53 IAGHSMGGYGAFKV..ALTF--PEKFQAAASMSGVM...DINYIikEDCFENFst.RAITG.EMT
  54 IAGHSMGGYGAFKV..ALTF--PEKFQAAASMSGVM...DINYIikEDCFENFst.RAITG.EMA
  55 VFGKDYGGYLSTYIlpAKGENQGQTFTCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  56 VFGKDYGGYLSTYIlpAKGENQGQTFTCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  57 VFGLDYGGYLSTYIlpAKGENQGQTFTCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  58 VFGKDYGGYLSTYIlpAKGENQGQTFTCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  59 VFGKDYGGYLSTYIlpAKGENQGQTFTCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  60 RPPSS---------..DLCFEKSWKIQICVSICSNL...QPCAV..SLGQKNF...SWIFG.---
  61 VFGKDYGGYLSTYLlpAKGDGQAPVFSCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  62 VFGKDYGGYLSTYLlpAKGDGQAPVFSCGSALSPIT...DF---..KLYASAFs..ERYLG.LHG
  63 IAGLSMGGFGALKI..GAKY--GEKYQAISAHSLIT...EVAQM..TLFVEEP...---LD.AYK
  64 IAGHSMGGYGTIKF..ALTQ--GDKFAKAVPLSAVFeaqNLMDL..EWNDFSK...EAIIG.NLS
  65 VAGLSMGGQGALLY..AARH--PGMFRATAAFSGSA...HPLLN..DESVDRI...MGFF-.---
  66 VVGNSTGGYCALKL..AAHH--PEVYAAGAGLSPYY...DAPND..PTTGDLF...QGDEG.LEK
  67 IFDHSMRGHGALIC..ALKN--PGKYRSLSAFAPIC...NPVLC..PWGKKAF...SGYLG.PDE
  68 IFDHSMRGHGALIC..ALKN--PGKYRSLSAFALIC...NPVLC..PWGKKAF...SGYLG.PDE
  69 IFGKGYGGYIASMI..LKSD--EKLFKCGSVVAPIT...DL---..KLYASAFs..ERYLG.MPS
  70 IFGKGYGGYIASMI..LKSD--EKLFKCGSVVAPIT...DL---..KLYASAFs..ERYLG.MPS
  71 --------------..--------------------...-----..-------...-----.---
  72 --------------..--------------------...-----..-------...-----.---
  73 ------GGHGALTI..YLKN--LDLYKSVSAFAPIT...NPINC..PWGQKAF...TNYLG.GNK
  74 IFGKGYGGYIASMI..LKSD--EKFFKCGAVVAPIS...DM---..KLYASAFs..ERYLG.MPS
  75 IWGWSFGGFMASNC..ILRG---EMFKMSIAVAPVT...NWRFY..DTVYT--...ERYMQ.TPQ
  76 VGGHSFGGYGALAV..A-------------------...-----..-------...-----.---


                   220          230          240        250       260  
                    |            |            |          |         |  
   1 A.QWEAY....DP.CLLIKNI...RHVGD...DRILIHVGDSDPFL.EEHLKPELLLEAVKATSW
   2 S.KWKAY....DA.THLVKSY...PG-SQ...LDILIDQGKDDQFLlDGQLLPDNFIAACTEK--
   3 S.KWKAY....DA.TCLVKAY...SG-SQ...IDILIDQGKDDEFLsNGQLLPDNFIAACTEK--
   4 S.KWKAY....DA.TCLVKAY...SG-SQ...IDILIDQGKDDEFLsNGQLLPDNFIAACTEK--
   5 S.KWKAY....DA.THLVKSY...PG-SQ...LDILIDQGKDDQFLlDGQLLPDNFIAACTEK--
   6 S.KWKAY....DA.THLVKSY...PG-SQ...LDILIDQGKDDQFLsDGQLLPDNFIAACTEK--
   7 S.KWKAY....DA.THLVKSY...PG-SQ...LDILIDQGKDDQFLsDGQLLPDNFIAACTEK--
   8 A.QWEAY....DP.CLLIKNI...RHVGD...DRILIHVGDSDPFL.EEHLKPELLLEAVKATSW
   9 S.AWTEW....DS.CELMLAS...QPQDA...IPVLIDQGDSDQFL.ADQLQPAVLAEAARQT--
  10 A.AWREW....DA.CALLEGA...S--ER...LPILVDQGERDDFL.AVQLKPEALRNAADKA--
  11 N.AWLEW....DS.CALMYAS...NAQDA...IPTLIDQGDNDQFL.ADQLQPAVLAEAARQK--
  12 A.AWRAY....DA.TALIAQA...A--ER...LPLLIDQGDADEFL.ENQLKTKLFEDAAKTA--
  13 T.TWKAY....DA.TALIADA...Q--ER...LPLLIDQGDADEFL.QNQLKTALFEGAAKAA--
  14 A.SWLAY....DA.SELVKQL...GYHS-...-QILIDQGTSDKFL.TEQLLTDVFAQACQAV--
  15 E.KWQQY....DA.SSLIQQG...Y--KV...QGMRIDQGLEDEFL.PTQLRTEDFIETCRVA--
  16 N.AWLEW....DS.CALMYAS...NAQDA...IPTLIDQGDNDQFL.ADQLQPAVLAEAARQK--
  17 E.KWQQY....DA.NSLIQQG...Y--KV...QGMRIDQGLEDEFL.PTQLRTEDFIETCRAA--
  18 E.KWQQY....DA.NSLIQQG...Y--KV...QGMRIDQGLEDEFL.PTQLRTEDFIETCRAA--
  19 A.QWEAY....DP.CLLIKNI...RHVGD...DRILIHVGDSDPFL.EEHLKPELLLEAVKATSW
  20 KeEWKSW....DA.SELVAGY...NGPP-...LELYLDQGSEDSFLkDGQLLPQNLVDACRAA--
  21 A.AWREY....DA.CALVEDG...A--RF...PEFLIDQGKADSFL.ENGLRPWLFEEAVKGT--
  22 E.AWLDY....HP.VSLISQG...QRVA-...-EIMVDQGLSDDFY.AEQLRTQNLEKICQEM--
  23 A.AWRRY....DA.CSLVEDG...A--RF...PEFLIDQGKADSFL.EKGLRPWLFEEAIKGT--
  24 N.QWLQY....DS.CHLLTHA...Q--HQ...LPILVDQGDGDQFL.ADQLQPAKLAELARQR--
  25 Q.AWRAY....DA.TLLIEDG...HR--F...PEILVDQGTADGFL.DDGLRPWLLEEACRKA--
  26 D.AWLDY....DP.VSLISQG...QRVA-...-EIMVDQGLSDDFY.AEQLRTPNLEKICQEM--
  27 KeEWKSW....DA.SELVAGY...NGPP-...LELYLDQGSEDSFLkDGQLLPQNLVDACRAA--
  28 S.KWKAY....DA.THLVKSY...PG-SQ...LDILIDQGKDDQFLlDGQLLPDNFIAACTEK--
  29 K.TWEHY....DP.VSLILQG...A--KL...PEIFIDQGLSDAFY.EDQLRTKSLERVCNEM--
  30 A.AWEEY....DA.TCLISKY...NNLS-...ATILIDQGENDQFY.PDQLLPSKFEEACKKV--
  31 D.DWALW....DA.THLVSQY...ESTP-...QELFIDQGAADNFLaGKQLLPENLLAAADGND-
  32 T.AWAAH....DA.TRLMQLA...NNPFP...GGILIDQGEADTFL.AEQLYPDDFAAACEAA--
  33 A.SWRSY....DA.TLLIEDG...HR--F...PELFVDQGTSDGFL.RDGLRPWLLEAACTRA--
  34 A.AWEEY....DA.TCLISKY...NNLS-...ATILIDQGENDQFY.PDQLLPSKFEEACKKV--
  35 L.SWQAW....DT.CALIKSA...P--ER...LPFFVDYGDADPFL.PTQLRPELLQAACTAA--
  36 A.DWGSY....DA.CLLLGEL...GWHG-...-DILIDQGAADQFL.DE-LQPEAMARLLAER--
  37 A.AWRPY....DA.CALIEDG...KGASF...DDILIDQGLADSFL.ENQLKPQLIEAAAAKA--
  38 K.MWHEY....DA.SQLVQKV...GYHS-...-SILIDQGTSDQFL.TGQLLPNVFEQACEKI--
  39 A.AWKRH....DS.TILMREK...GYPG-...-EVLIDQGASDQFL.DL-LKPEALAHAMAER--
  40 S.AWTEW....DS.CELMLAS...QPQDA...IPVLIDQGDSDQFL.ADQLQPAVLAEA------
  41 S.DWKEY....DA.TCLIKKC...NKIS-...TPILIDQGEDDKFL.AKQLLPRNFEEACKAV--
  42 S.TWNQY....DA.SEVLKAY...SGPK-...REILVDQGAADNFL.AQ-LKPETLKSKE-----
  43 G.NWETFkgsdNE.ILALADR...KQENK...PKLYAWCGKQDF--.---LFPGNEYAIAELKKR
  44 G.NWETFkgsdNE.ILALADR...KNEER...PKLYAWCGKQDF--.---LFPGNEYAIAELKKK
  45 G.NWETFkgsdNE.ILALADR...KNEER...PKLYAWCGKQDF--.---LFPGNEYATAELKKK
  46 G.NWETFkgsdNE.ILSLADR...KQENK...PKLYAWCGKQDF--.---LFPGNEYATAELKKL
  47 G.NWETFkgsdNE.ILALADR...KNEER...PKLYAWCGKQDF--.---LFPGNEYAIAELKKK
  48 S.NWQDY....NI.KDLAHGL...IFTK-...SNIIFDCGVDDFFI.EP-----NRALHQKLLDL
  49 S.NWQDY....NI.KDLAHGL...IFTK-...SNIIFDCGVDDFFI.EP-----NRALHQKLLDL
  50 G.QFDDP....DLdKHYLKNM...VAESDgk.TKFYAWCGYEDFLF.AT-----NEKAIADFQAQ
  51 G.QFDDP....DLdKHYLKNM...VAESDgk.TKFYAWCGYEDFLF.AT-----NEKAIADFQAQ
  52 G.EIRDWtts.PY.SLESLAK...KSDKK...TKLWAWCGEQDFLY.EA-----NNLAVKNLKKL
  53 S.QTGTE....ND.LFHLLETnltNNVEL...PALFQNCGTEDFLY.EDNLRFRDFALAK-----
  54 S.QTGTE....ND.LFHLLET...NLQNQvplPALFQNCGTEDFLY.EDNLRFRDFALEK-----
  55 L.DNRAY....EM.TKLAHRV...SALED...QQFLIIHATADEKI.HFQHTAELITQLIKGK--
  56 L.DNRAY....EM.TKLAHRV...SALED...QQFLIIHATADEKI.HFQHTAELITQLIKGK--
  57 L.DNRAY....EM.TKLAHRV...SALED...QQFLIIHATADEKI.HFQHTAELITQLIKGK--
  58 L.DNRAY....EM.TKLAHRV...SALED...QQFLIIHATADEKI.HFQHTAELITQLIKGK--
  59 L.DNRAY....EM.TKLAHRV...SALED...QQFLIIHATADEKI.HFQHTAELITQLIKGK--
  60 -.-----....--.-------...-----...--------------.------------------
  61 L.DNRAY....EM.AKVAHRV...SALEG...QQFLVIHATADEKI.HFQHTAELITQLIKGK--
  62 L.DNRAY....EM.AKVAHRV...SALEG...QQFLVIHATADEKI.HFQHTAELITQLIKGK--
  63 Q.AERAR....ED.VLTAIIE...NRENL...PRLRFDCGLDDELL.DY-----NRTLHQELKKN
  64 SvKGTEH....DP.YYLLDKA...VAEDKqi.PKLLIMCGKQDFLY.QDNL---DFIDYLSRK--
  65 -.AGQDN....DP.LRVWGDP...VA---...-QRGIWQAHDPFHL.AKRLR-------------
  66 R.A----....SL.WWCLKNA...PAPDT...SLLVTSSRTGETNY.KDTL---KFIDLVKGKRP
  67 S.KWKAY....DA.TCLVKSY...SG-SQ...IDILIDQGKDDEILsNGQLLPDNFIAACTEK--
  68 S.KWKAY....DA.TCLVKSY...SG-SQ...IDILIDQGKDDEILsNGQLLPDNFIAACTEK--
  69 K.EESTY....QA.ASVLHNV...HGLKE...ENILIIHGTADTKV.HFQHSAELIKHLIKA-GV
  70 K.EESTY....QA.ASVLHNV...HGLKE...ENILIIHGTADTKV.HFQHSAELIKHLIKA-GV
  71 -.-----....--.-------...-----...--------------.------------------
  72 -.-----....--.-------...-----...--------------.------------------
  73 A.DWEEY....DA.TSLVSKF...HDVS-...ATILIDQGGDDKFL.HEQLMPGKFEEACRLA--
  74 K.EESTY....QA.SSVLHNI...HGLKE...ENLLIIHGTADTKV.HFQHSAELIKHLIKA-GV
  75 E.NPEGY....DN.NSPLTYA...KNLN-...KKFLLVHGTADDNV.HVQNSMRLIESFVQYD--
  76 -.-----....--.-------...-----...--------------.------------------


           270            280       290         
            |              |         |         
   1 QDYVEIKKVHGF.....DHSYYFVSTFVPEHAEFHARNLGLI
   2 KIPVVFRLQEGY.....DHSYYFIATFITDHIRHHAKYL---
   3 KIPVVFRLQEGY.....DHSYYFIATFIADHIRHHAKYL---
   4 KIPVVFRLQEGY.....DHSYYFIATFIADHIRHHAKYL---
   5 KIPVVFRLQEDY.....DHSYYFIATFITDHIRHHAKYL---
   6 KIPVVFRSQEGY.....DHSYYFIATFITDHIRHHAKYL---
   7 KIPVVFRSQEGY.....DHSYYFIATFITDHIRHHAKYL---
   8 QDYVEIKKVHGF.....DHSYYFVSTFVPEHAEFHARNLGLI
   9 AWPMTLRIQPGY.....DHSYYFIASFIEDHLRFHARYL---
  10 GHPLELRLQPGY.....DHSYYFIASFIEDHLRHHAGVL---
  11 AWPMTLRIQPGY.....DHSYYFIASFIEDHLRFHAQYL---
  12 GYPVTVRLQPGY.....DHSYYFIASFIGEHIAHHARAL---
  13 GYPVTVRLQPGY.....DHSYYFISSFIGEHIAHHAAAL---
  14 NQPLNLRYQAGY.....DHSYYFIASFIADHIRHHATSL---
  15 NQPVDVRFHKGY.....DHSYYFIASFIGEHIAYHAEFL---
  16 AWPMTLRIQPGY.....DHSYYFIASFIEDHLRFHAQYL---
  17 NQPVDVRFHKGY.....DHSYYFIASFIGEHIAYHAAFL---
  18 NQPVDVRFHKGY.....DHSYYFIASFIGEHIAYHAAFL---
  19 QDYVEIKKVHGF.....DHSYYFVSTFVPEHAEFHARNLGLI
  20 QVPCVLNMREGY.....DHSYFYVASFIGEHIAYHARHL---
  21 DIGLTLRMHERY.....DHSYYFISTFMDDHLRWHAERL---
  22 NIKTLIRYHEGY.....DHSYYFVSSFIGEHIAYHANKLN--
  23 DIGLTLRMHDRY.....DHSYYFISTFMDDHLKWHAERL---
  24 DWPLMLRIQPGY.....DHSYFTIATFIEDHLRFHAAHL---
  25 GIALTLNMREGY.....DHSYFFISTFMGDHLRWHSERL---
  26 NIKTLIRYHEGY.....DHSYYFVSSFIGEHIAYHANKLN--
  27 QVPCVLNMREGY.....DHSYFYVASFIGEHIAYHAR-----
  28 KIPVVFRLQEGY.....DHSYYFIATFITDHIRHHAKYL---
  29 NINTSFRYHTGY.....DHSYYFISSFIGEHIAYHANRLR--
  30 NAPLLLRLHPGY.....DHSYYFIATFIEDHISHHAQAL---
  31 HIQTIFKQREGY.....DHSYFYIATFVAEHIAYHAALL---
  32 GQPLQLRRHPGY.....DHGYYFIQTFIEDHLRHHAAQL---
  33 GIALTLRMQDGY.....DHSYFFISTFMDDHLRWHAERL---
  34 NAPLLLRLHPGY.....DHSYYFIATFIEDHISHHAQAL---
  35 NHPLTLRMQPGY.....DHSYYFIASFIGDHMDWHG------
  36 RQAGVVRLQAGY.....DHSYYFVASFGEDHVRWHAERLN--
  37 GRKVTVRRQDGY.....DHSYFFISTFIGDHLAFHAQR----
  38 KQPLNLRYQAGY.....DHSYYLISTFIADHIHYHIKYLGLI
  39 RQPGTFRMQQGY.....DHSYFFVQSFMADHIPLA-------
  40 ------------.....-------------------------
  41 GAPLTLRMQPGY.....DHSYFFIATFIDDHIAHHSQFL---
  42 NAEIVVRMQAEF.....DHSYYFIASFMADHFEHHAKILNK-
  43 DFDVTYESSDGV.....HEWYYW-----TKKIECLLQWLP--
  44 GFDVTYESSDGV.....HEWYYW-----TKKIESVLQWLP--
  45 GFDVTYESSDGV.....HEWYYW-----TKKIESVLQWLP--
  46 GFDITYESSDGV.....HEWYYW-----TQKIESVLKWLP--
  47 GFDVTYESSDGV.....HEWYYW-----TKKIESVLQWLP--
  48 NIPHHYTEKPGG.....HSWVYW-----KDSIALHTHFF---
  49 NIPHHYTEKPGG.....HSWVYW-----KDSIALHTHFF---
  50 GLDIDYHKGHGK.....HEWYYW-----NQQLEVLLEWLP--
  51 GLDIDYHKGHGK.....HEWYYW-----NQQLEVLLEWLP--
  52 GFDVTYSHSAGT.....HEWYYW-----EKQLEVFLTTLP--
  53 NAPLEYREGPGD.....HDWDFW-----DKSLKEIIDWL---
  54 NAPLEYREGPGD.....HDWEFW-----DKSIKEIINWL---
  55 ---ANYSLQIYP.....DESHYFHSVALKQHL----------
  56 ---ANYSLQIYP.....DESHYFHSVALKQHL----------
  57 ---ANYSLQIYP.....DESHYFHSVALKQHL----------
  58 ---ANYSLQIYP.....DESHYFHSVALKQHL----------
  59 ---ANYSLQIYP.....DESHYFHSVALKQHL----------
  60 ------------.....-------------------------
  61 ---ANYSLQIYP.....DESHYFSSAALQQHL----------
  62 ---ANYSLQIYP.....DESHYFSSAALQQHL----------
  63 QVPHTYEEFVGS.....HKWEYW-QEHLEDTLIFFKDVL---
  64 NVPYQFEDGPGD.....HDYAYW-----DQAIKRA-------
  65 SIPVYLSCGDG-.....-------------------------
  66 TRISSIILESGG.....HNFNTW-RREIPATLRWLDERL---
  67 KIPVVFRLQEGY.....DHSYCFIATLIADHIRHHAKYL---
  68 KIPVVFRLQEGY.....DHSYCFIATFIADHIRHHAKYL---
  69 NYTMQVYPDEGHnv7skYHLYSTILKFFSDCLKEEISVL---
  70 NYTMQVYPDEGHnv7skYHLYSTILKFFSDCLKEEISVL---
  71 ------------.....-------------------------
  72 ------------.....-------------------------
  73 NVPLLLRTHPGY.....DHSYFFISTFIDDHIRHHVQAL---
  74 NYTLQVYPDEGYhi7skHHFYSTILRFFSDCLKEEVSVL---
  75 ------------.....-------------------------
  76 ------------.....-------------------------