a2m2html output for file tmp.a2m

Citations (SAM, SAM-T99, HMMs)

R. Hughey, A. Krogh, Hidden Markov models for sequence analysis: Extension and analysis of the basic method, CABIOS 12:95-107, 1996.
K. Karplus, C. Barrett, R. Hughey, Hidden Markov models for detecting remote protein homologies, Bioinformatics 14(10):846-856, 1998.
A. Krogh et al., Hidden Markov models in computational biology: Applications to protein modeling, JMB 235:1501-1531, Feb 1994.

Sequence numbers correspond to the following labels:

- T0194 Conserved hypothetical protein, M. pneumoniae
- gi|16080601|ref|NP_391428.1|_51:278 (NC_000964) alternate gene name: degV, sacU~similar to hypothetical proteins [Bacillus subtilis]
- gi|729311 sp|P32436|DEGV_BACSU DegV protein
- gi|1075851|pir||D30191 conserved hypothetical protein yviA - Bacillus subtilis
- gi|39848|emb|CAA79225.1| (Z18629) U3 [Bacillus subtilis]
- gi|1762331|gb|AAC44939.1| (U56901) degV gene product [Bacillus subtilis]
- gi|2636074|emb|CAB15565.1| (Z99122) alternate gene name: degV, sacU~similar to hypothetical proteins [Bacillus subtilis]
- gi|21397658|ref|NP_653643.1|_51:278 (NC_003995) DUF194, Uncharacterized protein, DegV family COG1307 [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
- gi|19745935|ref|NP_607071.1|_50:277 (NC_003485) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|19748092|gb|AAL97570.1| (AE010021) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|15674893|ref|NP_269067.1|_50:277 (NC_002737) conserved hypothetical protein [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
- gi|13622032|gb|AAK33788.1| (AE006536) conserved hypothetical protein [Streptococcus pyogenes M1 GAS]
- gi|21910122|ref|NP_664390.1|_50:277 (NC_004070) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|21904314|gb|AAM79193.1| (AE014148) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|16801719|ref|NP_471987.1|_53:280 (NC_003212) similar to B. subtilis YviA (DegV) protein [Listeria innocua]
- gi|16415194|emb|CAC97884.1| (AL596173) similar to B. subtilis YviA (DegV) protein [Listeria innocua]
- gi|18266389|gb|AAL67545.1|AF459920_1_51:277 (AF459920) hypothetical protein YviA [Bacillus licheniformis]
- gi|15923739|ref|NP_371273.1|_52:281 (NC_002758) conserved hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]
- gi|15926426|ref|NP_373959.1| (NC_002745) conserved hypothetical protein [Staphylococcus aureus subsp. aureus N315]
- gi|13700640|dbj|BAB41937.1| (AP003131) conserved hypothetical protein [Staphylococcus aureus subsp. aureus N315]
- gi|14246518|dbj|BAB56911.1| (AP003360) conserved hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]
- gi|14861054|dbj|BAB62083.1| (AB002692) homologous to degORF3 in Bacillus subtilis~llmORF3 [Staphylococcus aureus]
- gi|21282440|ref|NP_645528.1|_52:281 (NC_003923) conserved hypothetical protein [Staphylococcus aureus subsp. aureus MW2]
- gi|21203877|dbj|BAB94576.1| (AP004824) conserved hypothetical protein [Staphylococcus aureus subsp. aureus MW2]
- gi|15901400|ref|NP_346004.1|_50:278 (NC_003028) degV family protein [Streptococcus pneumoniae TIGR4]
- gi|14973048|gb|AAK75644.1| (AE007451) degV family protein [Streptococcus pneumoniae TIGR4]
- gi|21400769|ref|NP_656754.1|_51:284 (NC_003995) DUF194, Uncharacterized protein, DegV family COG1307 [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
- gi|15903458|ref|NP_359008.1|_50:278 (NC_003098) Conserved hypothetical protein [Streptococcus pneumoniae R6]
- gi|15459069|gb|AAL00219.1| (AE008512) Conserved hypothetical protein [Streptococcus pneumoniae R6]
- gi|20807934|ref|NP_623105.1|_50:277 (NC_003869) conserved hypothetical protein [Thermoanaerobacter tengcongensis]
- gi|20516503|gb|AAM24709.1| (AE013106) conserved hypothetical protein [Thermoanaerobacter tengcongensis]
- gi|18309008|ref|NP_560942.1|_53:287 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
- gi|18143683|dbj|BAB79732.1| (AP003185) conserved hypothetical protein [Clostridium perfringens str. 13]
- gi|15616189|ref|NP_244494.1|_53:282 (NC_002570) BH3627~unknown conserved protein [Bacillus halodurans]
- gi|10176251|dbj|BAB07346.1| (AP001519) BH3627~unknown conserved protein [Bacillus halodurans]
- gi|16801043|ref|NP_471311.1|_52:279 (NC_003212) similar to hypothetical proteins [Listeria innocua]
- gi|16414478|emb|CAC97207.1| (AL596170) similar to hypothetical proteins [Listeria innocua]
- gi|16804552|ref|NP_466037.1|_53:280 (NC_003210) similar to B. subtilis YviA (DegV) protein [Listeria monocytogenes EGD-e]
- gi|16412002|emb|CAD00592.1| (AL591983) similar to B. subtilis YviA (DegV) protein [Listeria monocytogenes]
- gi|16078175|ref|NP_388992.1|_49:280 (NC_000964) yitS [Bacillus subtilis]
- gi|7475092|pir||D69841 hypothetical protein yitS - Bacillus subtilis
- gi|1620923|emb|CAB01833.1| (Z79580) putative ORF [Bacillus subtilis]
- gi|2145412|emb|CAA70629.1| (Y09476) YitS [Bacillus subtilis]
- gi|2633447|emb|CAB12951.1| (Z99109) yitS [Bacillus subtilis]
- gi|15900979|ref|NP_345583.1|_52:275 (NC_003028) degV family protein [Streptococcus pneumoniae TIGR4]
- gi|14972588|gb|AAK75223.1| (AE007412) degV family protein [Streptococcus pneumoniae TIGR4]
- gi|13508403|ref|NP_110353.1|_3:237 (NC_000912) conserved hypothetical protein [Mycoplasma pneumoniae]
- gi|2496451 sp|P75127|Y450_MYCPN Hypothetical protein MG450 homolog (K05_orf237)
- gi|2146095|pir||S73504 degV protein homolog K05_orf237 - Mycoplasma pneumoniae (strain ATCC 29342)
- gi|1673841|gb|AAB95826.1| (AE000019) conserved hypothetical protein [Mycoplasma pneumoniae]
- gi|16803903|ref|NP_465388.1|_52:279 (NC_003210) similar to hypothetical proteins [Listeria monocytogenes EGD-e]
- gi|16411317|emb|CAC99941.1| (AL591981) similar to hypothetical proteins [Listeria monocytogenes]
- gi|21400125|ref|NP_656110.1|_53:281 (NC_003995) DUF194, Uncharacterized protein, DegV family COG1307 [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
- gi|12045309|ref|NP_073120.1|_3:237 (NC_000908) conserved hypothetical protein [Mycoplasma genitalium]
- gi|1351587 sp|P47688|Y450_MYCGE Hypothetical protein MG450
- gi|1361698|pir||G64249 hypothetical protein MG450 - Mycoplasma genitalium
- gi|3845043|gb|AAC72470.1| (U39726) conserved hypothetical protein [Mycoplasma genitalium]
- gi|21283044|ref|NP_646132.1|_51:276 (NC_003923) conserved hypothetical protein [Staphylococcus aureus subsp. aureus MW2]
- gi|21204483|dbj|BAB95180.1| (AP004826) conserved hypothetical protein [Staphylococcus aureus subsp. aureus MW2]
- gi|15894902|ref|NP_348251.1|_57:277 (NC_003030) Uncharacterized protein from DegV (B.subtilis) family [Clostridium acetobutylicum]
- gi|15024581|gb|AAK79591.1|AE007671_9 (AE007671) Uncharacterized protein from DegV (B.subtilis) family [Clostridium acetobutylicum]
- gi|15924415|ref|NP_371949.1|_51:276 (NC_002758) conserved hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]
- gi|15927006|ref|NP_374539.1| (NC_002745) conserved hypothetical protein [Staphylococcus aureus subsp. aureus N315]
- gi|13701223|dbj|BAB42518.1| (AP003133) conserved hypothetical protein [Staphylococcus aureus subsp. aureus N315]
- gi|14247196|dbj|BAB57587.1| (AP003362) conserved hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]
- gi|15675397|ref|NP_269571.1|_53:278 (NC_002737) conserved hypothetical protein [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
- gi|19746447|ref|NP_607583.1| (NC_003485) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|13622583|gb|AAK34292.1| (AE006583) conserved hypothetical protein [Streptococcus pyogenes M1 GAS]
- gi|19748649|gb|AAL98082.1| (AE010066) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|21910685|ref|NP_664953.1|_53:278 (NC_004070) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|21904888|gb|AAM79756.1| (AE014159) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|15644217|ref|NP_229268.1|_54:280 (NC_000853) conserved hypothetical protein [Thermotoga maritima]
- gi|7462235|pir||E72246 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
- gi|4982034|gb|AAD36536.1|AE001798_1 (AE001798) conserved hypothetical protein [Thermotoga maritima]
- gi|21911014|ref|NP_665282.1|_53:278 (NC_004070) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|21905222|gb|AAM80085.1| (AE014164) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|15675739|ref|NP_269913.1|_51:281 (NC_002737) conserved hypothetical protein [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
- gi|19746849|ref|NP_607985.1| (NC_003485) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|13622959|gb|AAK34634.1| (AE006617) conserved hypothetical protein [Streptococcus pyogenes M1 GAS]
- gi|19749089|gb|AAL98484.1| (AE010104) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|19746606|ref|NP_607742.1|_53:278 (NC_003485) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|19748824|gb|AAL98241.1| (AE010082) conserved hypothetical protein [Streptococcus pyogenes MGAS8232]
- gi|12045184|ref|NP_072995.1|_53:293 (NC_000908) conserved hypothetical protein [Mycoplasma genitalium]
- gi|1351545 sp|P47568|Y326_MYCGE Hypothetical protein MG326
- gi|1361588|pir||A64236 hypothetical protein homolog MG326 - Mycoplasma genitalium
- gi|3844906|gb|AAC71550.1| (U39714) conserved hypothetical protein [Mycoplasma genitalium]
- gi|18311491|ref|NP_563425.1|_55:279 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
- gi|18146175|dbj|BAB82215.1| (AP003194) conserved hypothetical protein [Clostridium perfringens str. 13]
- gi|15673544|ref|NP_267718.1|_51:274 (NC_002662) conserved hypothetical protein [Lactococcus lactis subsp. lactis]
- gi|12724565|gb|AAK05660.1|AE006387_3 (AE006387) conserved hypothetical protein [Lactococcus lactis subsp. lactis]
- gi|21911203|ref|NP_665471.1|_51:281 (NC_004070) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|21905415|gb|AAM80274.1| (AE014168) conserved hypothetical protein [Streptococcus pyogenes MGAS315]
- gi|13508211|ref|NP_110160.1|_52:290 (NC_000912) conserved hypothetical protein [Mycoplasma pneumoniae]
- gi|2496388 sp|P75312|Y326_MYCPN Hypothetical protein MG326 homolog (P01_orf293)
- gi|2146094|pir||S73695 degV homolog P01_orf293 - Mycoplasma pneumoniae (strain ATCC 29342)
- gi|1674048|gb|AAB96017.1| (AE000035) conserved hypothetical protein [Mycoplasma pneumoniae]
- gi|15903063|ref|NP_358613.1|_52:275 (NC_003098) Conserved hypothetical protein [Streptococcus pneumoniae R6]
- gi|15458636|gb|AAK99823.1| (AE008474) Conserved hypothetical protein [Streptococcus pneumoniae R6]
- gi|16802633|ref|NP_464118.1|_356:579 (NC_003210) similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical [Listeria monocytogenes EGD-e]
- gi|16409966|emb|CAC98669.1| (AL591975) similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical [Listeria monocytogenes]
- gi|4580621|gb|AAD24444.1|AF118389_1_11:235 (AF118389) unknown [Streptococcus suis]
- gi|15806984|ref|NP_295709.1|_54:274 (NC_001263) degV protein [Deinococcus radiodurans]
- gi|7471794|pir||E75330 degV protein - Deinococcus radiodurans (strain R1)
- gi|6459775|gb|AAF11538.1|AE002036_9 (AE002036) degV protein [Deinococcus radiodurans]
- gi|21400546|ref|NP_656531.1|_47:267 (NC_003995) DUF194, Uncharacterized protein, DegV family COG1307 [Bacillus anthracis A2012] [Bacillus anthracis str. A2012]
- gi|15894235|ref|NP_347584.1|_57:280 (NC_003030) Uncharacterized protein, DegV family [Clostridium acetobutylicum]
- gi|15023851|gb|AAK78924.1|AE007610_4 (AE007610) Uncharacterized protein, DegV family [Clostridium acetobutylicum]
- gi|15896529|ref|NP_349878.1|_48:281 (NC_003030) Uncharacterized conserved protein, DegV family [Clostridium acetobutylicum]
- gi|15026362|gb|AAK81218.1|AE007825_2 (AE007825) Uncharacterized conserved protein, DegV family [Clostridium acetobutylicum]
- gi|15675555|ref|NP_269729.1|_53:278 (NC_002737) conserved hypothetical protein [Streptococcus pyogenes] [Streptococcus pyogenes M1 GAS]
- gi|13622758|gb|AAK34450.1| (AE006600) conserved hypothetical protein [Streptococcus pyogenes M1 GAS]
- gi|18310292|ref|NP_562226.1|_53:278 (NC_003366) conserved hypothetical protein [Clostridium perfringens]
- gi|18144972|dbj|BAB81016.1| (AP003190) conserved hypothetical protein [Clostridium perfringens str. 13]
- gi|16799674|ref|NP_469942.1|_358:580 (NC_003212) similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical [Listeria innocua]
- gi|16413039|emb|CAC95831.1| (AL596165) similar to a fusion of two types of conserved hypothetical proteinconserved hypothetical [Listeria innocua]
- gi|15828830|ref|NP_326190.1|_49:273 (NC_002771) conserved hypothetical protein [Mycoplasma pulmonis]
- gi|14089773|emb|CAC13532.1| (AL445564) conserved hypothetical protein [Mycoplasma pulmonis]
- gi|11065683|emb|CAC14295.1|_2:206 (AJ276209) ORF1 [Clostridium sticklandii]
- gi|15900637|ref|NP_345241.1|_53:280 (NC_003028) conserved hypothetical protein [Streptococcus pneumoniae TIGR4]
- gi|15902696|ref|NP_358246.1| (NC_003098) Conserved hypothetical protein [Streptococcus pneumoniae R6]
- gi|14972216|gb|AAK74881.1| (AE007382) conserved hypothetical protein [Streptococcus pneumoniae TIGR4]
- gi|15458238|gb|AAK99456.1| (AE008443) Conserved hypothetical protein [Streptococcus pneumoniae R6]
- gi|15829237|ref|NP_326597.1|_53:278 (NC_002771) conserved hypothetical protein [Mycoplasma pulmonis]
- gi|14090181|emb|CAC13939.1| (AL445565) conserved hypothetical protein [Mycoplasma pulmonis]
- gi|13357748|ref|NP_078022.1|_3:212 (NC_002162) conserved hypothetical [Ureaplasma urealyticum]
- gi|11356784|pir||D82921 conserved hypothetical UU190 [imported] - Ureaplasma urealyticum
- gi|6899155|gb|AAF30597.1|AE002119_2 (AE002119) conserved hypothetical [Ureaplasma urealyticum]
- gi|15672563|ref|NP_266737.1|_364:590 (NC_002662) conserved hypothetical protein [Lactococcus lactis subsp. lactis]
- gi|12723471|gb|AAK04679.1|AE006291_13 (AE006291) conserved hypothetical protein [Lactococcus lactis subsp. lactis]
- gi|13358099|ref|NP_078373.1|_53:283 (NC_002162) conserved hypothetical [Ureaplasma urealyticum]
- gi|11356822|pir||A82879 conserved hypothetical UU535 [imported] - Ureaplasma urealyticum
- gi|6899539|gb|AAF30948.1|AE002152_7 (AE002152) conserved hypothetical [Ureaplasma urealyticum]
- gi|15644356|ref|NP_229408.1|_5:206 (NC_000853) conserved hypothetical protein [Thermotoga maritima]
- gi|7462191|pir||D72235 conserved hypothetical protein - Thermotoga maritima (strain MSB8)
- gi|4982179|gb|AAD36675.1|AE001804_19 (AE001804) conserved hypothetical protein [Thermotoga maritima]

              10        20         30        40        50              
              |         |          |         |         |              
   1 MANAPKGVKFSTSQTTEEIVRAKVSELV.EQYDLIIGIPIDKEISASYANWKLV...EKDY....
   2 -EVKKHNELPTTSQPPIGELVALYEELG.KSYDAVISIHLSSGISGTFSSAAAA...DSMV....
   3 -KVREQEELPKTSQPAIGKFVELYEELS.KDYDAVISIHLSSGISGTYQTSTTA...GQMV....
   4 QKMADSQNLPKTSQPSLSELDNLLGLLSsKGYTHVIGLFLAGGISGFWQNIQFL...AEEH....
   5 QKMADSQNLPKTSQPSLSELDNLLGLLSsKGYTHVIGLFLAGGISGFWQNIQFL...AEEH....
   6 QKMADSKNLPKTSQPSLSELDNLLGLLSsKGYTHVIGLFLAGGISGFWQNIQFL...AEEH....
   7 -KVKEAENFPTSSQPAPGEFIQLFEKLKeQGFDTVISIHLSSGISGTFQNAASA...GELI....
   8 -EVKAHENLPTTSQPAYGELISLYEKLG.ETYDAVISIHLSSGISGTFNSAVSA...SGML....
   9 -KMASSQTIPTTSQPAIGEWITKYEMLRdQGYTDIIVICLSSGISGSYQSSYQA...GEMV....
  10 -KMASSQTIPTTSQPAIGEWITKYEMLRdQGYTDIIVICLSSGISGSYQSSYQA...GEMV....
  11 QKMAQASELPKTSQPSIAKLDEILTSLKeQGYTHALGLFLSSGISGFYQNIQYM...VDDY....
  12 -QKMREGAVYRTSLPSLETFQEKFVSYA.KEGNPCIYLAFSSELSGTYQSSVLI...KEEVkety
  13 QKMAQASELPKTSQPSIAKLDEILTSLKeQGYTHALGLFLSSGISGFYQSIQYM...VDDY....
  14 YKLLREGKMPTTTQASPVEFMEVFEDLL.KSFDYVIAIILTSKFSGTYQSAVIA...RDMV....
  15 -NKLREGIMPSTSQVNSFRFVEAFEEYV.KQGISILYLAFSSALSGTYNSSLIA...REELleky
  16 --LKHEEKLPTTSQPAVGLFVETFERLAkEGFEVVISIHLSSKISGTYQSALTA...GSMV....
  17 -RMAETKELPKSSQPAIGSFVEAYEKYT.AEGYEILSIHLTEKLSGTVNAARQA...ADMV....
  18 -KVKEAENFPTSSQPAPGEFIHLFENLKeQGFDTVISIHLSSGISGTFQNAASA...GELI....
  19 FEAMQNGETPKTSQASPQTIKNVFLQYA.ETGDPALYIAFSSGLSGTYQTAVMI...ANEVkeef
  20 -LMQESKNLPKTSQPPVGVFAEIFEDLC.KDGGQILAIHMSHALSGTVEAARQG...ASLS....
  21 --NAPKGVKFSTSQTTEEIVRAKVSELV.EQYDLIIGIPIDKEISASYANWKLV...EKDY....
  22 -RMAETKELPKSSQPAIGSFVEAYEKYT.AEGYEILSIHLTEKLSGTVNAARQA...ADMV....
  23 EEMIKSEELPKTSQPAMGTFVEMYDKLG.EDGSEVLSIHMTSGMSGTVATANSA...ASMT....
  24 --NAPKGVKFSTSQTSEEEVRDKVKSII.NDYDLIIGIPIDKEISTSYLNWKIV...EKEF....
  25 -NHIENDEDVKTSQPAIGEFISAYEELG.KDGSEIISIHLSSGLSGTYNTAYQA...SQMV....
  26 --------VPSTSLPSMGDMESLYEKLEaEGYTHVIGVTISSNLSGTYNSLKLV...SEGH....
  27 -NHIENDEDVKTSQPAIGEFISAYEELG.KDGSEIISIHLSSGLSGTYNTAYQA...SQMV....
  28 --MKASKSLPKTSQPPVGLFAETYENLVkKGVTDIVAIHLSPALSGTIEASRQG...AEIA....
  29 --MKASKSLPKTSQPPVGLFAETYENLVkKGVTDIVAIHLSPALSGTIEASRQG...AEIA....
  30 --IREAGSVPKTSQPSVEDFKKRYLKYKeEDYDVVLVLTLSSKLSGTYNSAVLA...SKEV....
  31 -TMYQSSKATTSSCPSPEAFLQAY----.RGADNVIVMTITGTLSGSHNSARLA...KNELleen
  32 LKKMKAGSHPQTSQINVGEFEKVFREHA.RNNKALLYLAFSSVLSGTYQSALMA...RDLVredy
  33 -TMYQSSKATTSSCPSPEAFLQAY----.RGSDNVIVMTITGTLSGSHNSARLA...KNELleen
  34 -KENPHGLNISTSLPRQSDLLKIFEEIK.TKYDRFIFLPLSKGLSGTYDMLVQL...AKELseqn
  35 ------NEVPTTSLCSPDYINSVLDKLEaEGYTHLIGIFISSSLSGTFNAARLV...IEER....
  36 --MAEAQEVPKTSQPRVAELDRLLKDLEkQGYTHVLGLFLPAAISGFYQNIFYL...QSEY....
  37 LKKMKAGSHPQTSQINVGEFEKVFREHA.RNNKALLYLAFSSVLSGTYQSALMA...CDLVredy
  38 -KEHPQGLNISTSLPRQADLIELIEAIK.DKYDRFVFLPLSKGLSGTYDMIVQA...VKPL....
  39 -LMQESKNLPKTSQPPVGVFAEIFEDLC.KDGGQILAIHMSHALSGTVEAARQG...ASLS....
  40 QEKLRKQTKMSTAQPTIRTVDALLSFLE.NKYEHVLVISVAAKLSGTYQLIKQR...IKVR....
  41 --MEASKSAAGSACPSPQAYQAAF----.EGAENIIVVTITGGLSGSFNAARVA...RDMYieeh
  42 ----AGKAIPSTSQPSPAEFAQAYAQAL.EHADEVLSLHISGQLSGTVGSARLA...AQEF....
  43 YNALNEGKTVTTSQPNIGEMVELFSKCK.EEYEEGFAVAISGKVSGTYQNMKLA...AEMA....
  44 --------VPKSSMPSLQDMEDLYKKLEeEGYTHAIGITLSSGLSGIFNGLKMI...ADEH....
  45 YEKMNEKGIPKSSQPSIEDLCSVMEEVV.SVGDELLCIFISSDMSGTYSTAHIA...RDMVieky
  46 -TMYQSSKATTSSCPSPEAFLQAY----.RGADNVIVMTITGTLSGSHNSARLA...KNELleen
  47 --IEREDTLPTTAQIVPTRFIEKYKGYL.EEGYKVISIHISSNMSGTYQSACLA...KTEL....
  48 -QKLTQQHKMSTAQPTIRTVDALLSFLE.NKYQHVLVIAVSAKLSGTYQLIKQR...IKAR....
  49 FEIFKKNSKTSTSASSRGEIISLFDDIT.SKYDKVVVFPISYKLSSQYQNLDLI...AREY....
  50 -----------------------FSEVV.NSGNEVICITMSSALSGTYNSALIA...SREF....
  51 -TMYATAEASKSACPSPDDYLRAF----.EGAKNIFLVTITGTLSGSHNSAQLA...KNIYledh
  52 --KIIQASDIKTSLPISSTIEKAVNESS.QKYNDVLVLPIASFLSGTISVINVY...AQKH....
  53 --------------------WKNLDELF.LKYDRVVILTLSSGLSSYFESLSII...KEDY....
  54 -EKYNKNLKMTTSQPSIQSVDSLFSFLE.GKYEHIIVISVSSKLSGTYQLLNQRitaKKSL....
  55 YEDIDNGYTFQTSCTPYGVLIEAIEQKL.QEYEKIIFIGISSGFSSQFNNAKNL...EKEY....
  56 -----------------------LRDIIsEGCTRIYCVHLSSKLSAFYNVMKSV...TERLkekf


           60        70        80        90       100         110      
           |         |         |         |         |           |      
   1 .A...SKFHVLDARAVEMIIDWLINDIKGWLNTNPYSREGLDRFVEQYRKK..TAAVLFVTDTKP
   2 .Dn..IDVYPFDSEISCLAQGFYALKAAELIKNGASSPEDIIKELEEMKKT..VRAYFMVDDLAH
   3 .Eg..IDVYTYDSEISCEVQGFYVREGARLASEGK-DPKEIIARFDEMKKT..MDAYFVVDDLHH
   4 .Pe..IEMAFPDSKITSAPLGSMVKNVLDWSRQGM-TFQAILNKLQEQIDR..TTAFIMVDDLNH
   5 .Pe..IEMAFPDSKITSAPLGSMVKNVLDWSRQGM-TFQAILNKLQEQIDG..TTAFIMVDDLNH
   6 .Pe..IEMAFPDSKITSAPLGSMVKNVLDWSRQGM-TFQAILNKLQEQIDG..TTAFIMVDDLNH
   7 .Dg..LNVVAYDSELSCMAQGMFAVKAAEMALANE-PLERIISELDKIKKA..QDAYFMVDDLNN
   8 .Eg..IKVYPFDSEISCMAQGFYAIEAAEMAEKGA-APEEIIRHLDHMKTS..MRAYFMVDDLSH
   9 .Eg..VNVHAFDSKLAAMIEGCYVLRAIEMVEEGY-EPQQIIDDLTNMREH..TGAYLIVDDLKN
  10 .Eg..VNVHAFDSKLAAMIEGCYVLRAIEMVEEGY-EPQQIIDDLTNMREH..TGAYLIVDDLKN
  11 .Eg..LTIAFPDTLITSAPLGIMVESVFNWRDQGD-DFASIQDKLAIQISR..TSAFIMVDDLDH
  12 aN...LDLEIIDTKCASLGQGLVVLEAAKMAKDGA-SKEDILKRVDFLMNH..MEHIFTVADLQY
  13 .Eg..LTIAFPDTLITSAPLGIMVESVFNWRDQGD-DFASIQDKLAIQISR..TSAFIMVDDLDH
  14 .Dk..NRIEVIDSRHFTLGNGMLVLKAARMAVEGA-SKEEIVSTVYETIPR..IRGIMVFDSLDY
  15 pD...ADIKIVDTRAACLGQGLLVYYAAQMKKDGK-SIDEIYSWVEENKNK..LCHYFTVDSLDH
  16 .Eg..IEVIGYDSGISCEPQANFVAEAAKLVKEGA-DPQTIIDHLDEVKKR..TNALFVVHDLSH
  17 .E...GNITVVDCDYTARGQAFQVLKAAEMAQAGDYSVEEIHAAINDIRDK..TKLYIVVVTLDN
  18 .Eg..LNVVAYDSELSCMAQGMFAVKAAEMALANE-PLDQIIQKLDKIKQA..QDAYFMVDDLNN
  19 pD...FDLRVIDSKCASLGYGLAVRHAADLCINGN-TIQEIETSVKNFCSQ..LEHIFTVDDLTY
  20 .T...ADVTVVDSSFTDQALKFQVVEAAKLAQEGK-DMEAILSHVEEVKNH..TELYIGVSTLEN
  21 .A...SKFHVLDARAVEMIIDWLINDIKGWLNTNPYSREGLDRFVEQYRKK..TAAVLFVTDTKP
  22 .E...GNITVVDCDYTARGQAFQVLKAAEMAQSGDYSVEEIHAKINDIRDK..TKLYIVVVTLDN
  23 .D...TKVTVVDSQFITHALAYQVVEAAKMANEGR-SLEEILKRVDEVRKN..TRLYVVVDTLEN
  24 .E...DKFHVLDSRIVEVLIAWLISDIKVWLKNNQYSRAGLDEFVYNFRNK..CGAILFVTDTKP
  25 .D...ANVTVIDSKSISFGLGYQIQHLVELVKEGV-STSEIVKKLNHLREN..IKLFVVIGQLNQ
  26 .En..IKSFIFDSRSITMGEGAIIKECGEMILQGK-NFDYIVEKMPKMREN..IKVYYIVDTLKY
  27 .D...ANVTVIDSKSISFSLGYQIQHLVELVKEGV-STSEIVKKLNHLREN..IKLFVVIGQLNQ
  28 .E...APVTVLDSGFTDQAMKFQVVEAAKMAKAGA-SLNEILAAVQAIKSK..TELYIGVSTLEN
  29 .E...TPVTVLDSGFTDQAMKFQVVEAAKMAKAGA-SLNEILAAVQAIKSK..TELYIGVSTLEN
  30 .D...IPVYVVDTLLASGAIPLPARVAREMLENGA-TIEEVLKKLDERMKNkdFKAIFYVSNFDY
  31 pN...VNIHLIDSLSAGGEMDLLVLELERLINLGL-SFEEVVKQITAYQQK..TRLIFVLAKVDN
  32 pD...AVIEIVDTLAAAGGEGYLTILAAEARDSGK-NLLETKDIVEAVIPR..LRTYFLVDDLFH
  33 pN...VNIHLIDSLSAGGEMDLLVLELERLINLGL-SFEEVVKQITAYQQK..TRLIFVLAKVDN
  34 kD...KEFLVFETSDIAISLKWLVEDIKALVDKGC-DNQTIKAKVESHKQN..ILSAVTLKNLVQ
  35 .Ss..FKYYLFDSKIIGYPLGSIVIKAAEFVKEGK-SFEEIIEALSIIREA..TTGFYTLNTLEY
  36 .Eq..MKVVFPETFITSSPLGYMVETVLDLAEAGV-EFEEIIAKFEEQRDG..DRAYMLVDDLHW
  37 pD...AVIEIVDTLAAAGGEGYLTILAAEARDSGK-NLLETKDIVEAVIPR..LRTYFLVDDLFH
  38 .StpkKEFVVLETSDIAISLKWLVQEVKALTDTNC-PTKAIAEVVDQHKQS..IFTAVTVKNLVQ
  39 .T...ADVIVVDSSFTDQALKFQVVEAAKLAQEGK-DMEAILSHVEEVKNH..TELYIGVSTLEN
  40 .ElssDWIRVIDSKLNSVAQGILVKQAVELVESGK-SWESIYPEVEQMIER..TFIYVAVADLSP
  41 pN...VNIHLIDSLSASGEMDLLVHQINRLISAGL-DFPQVVEAITHYREH..SKLLFVLAKVDN
  42 .G...GRVTVVDTHTVTLGLGLQVLRAAELVRAGQ-SVPQIVQTLERVYPQ..ADLRFTVDTLDF
  43 .G...FPLTVLDSETTSYPMDELIRKAKSLYNDGM-TLQDIHKTLVDEKRR..PFHVF-PKSLKG
  44 .Sk..IKSFIYDSKLISLGEGALVEECSKMIHNNK-SFDEIVKAIPEIRKK..IHLFFVVGTLDY
  45 kD...AKIEILDSRSNCMQLGFAAISAARAAMDGK-SLEEVKLAAEENMKK..SRFLFIPDNLVY
  46 pN...VNIHLIDSLSAGGEMDLLVLELERLIKLGL-SFEEVVKQITAYQQK..TRLIFVLAKVDN
  47 .Es..DDIVVIDSRNVTVGLGLIILKAARLIESGI-TLEDLEKEILEYRNH..IKSTIAFESLDN
  48 .DlspEWIRVIDSKLNSVAQGLLVKQAVELVEAGK-PFDEVTQKIEQLTAQ..TFIYVAVADLAP
  49 .K...-NIHIVKSKHLSFLTIVQLIKFEKAIGQNQ-SFDEELKKLSHWDES..QKVLLIPEYNDA
  50 .Da..NKIRVIDSKAITLGYGMIVIEAAKMASNGI-GIDDIESRVRDLVNN..MEYLIIFDTLEY
  51 pD...TKIHVIDSLSAGGEVDLLVEKLNDLIDQGL-SFEEVVEAITAYQEK..TKLLFVLAKVDN
  52 .K...-NVHIFDNHFVANTIVEIGLQAKKMYEQENKSIKEIITWLEEINTK..TITFLSLKTLDY
  53 .Kd..KHLVCIDSRSVSIGILWLVDEINLLLKNNP-SDEELISLVKQRSQK..IIGGVIVNNLDQ
  54 .E...NRVHLIDSKLNSVAQGLLVKQVAKLISEER-SIESVLNETEKITDR..IFIYVVVEDLSP
  55 .Q...DKLFVVDTEDFGYSLEHLVYKIKAMLSNNI-SFGDILKMINKHHDY..TSSFLACENITG
  56 pS...VTFRVIDTRQVSIGAGYVLLKLMESVKDGR---EDLERVVQEANER..IKIRFSVLEFDY


       120       130       140       150       160       170          1
        |         |         |         |         |         |           
   1 LVAGGRLSNLKSFIIKSLKFHLLISFLGENGKLQFFDKARSAHDAHKLAVKFLK.KQLLK..HSA
   2 LQRGGRLSSAQAFIGSLLKVKPILHF--DNKVIVPFEKIRTRKKAISRIYELLD.EDASK..---
   3 LQRGGRLNSAQAFIGSLLQVKPVLYF--RDKIIIPFEKIRTRKKALKRIIEIFD.EQASK..---
   4 LVKGGRLSNGSALLGNLLSIKPILRF-DEEGKIVVYEKVRTEKKAMKRLVEILN.DLIAD..---
   5 LVKGGRLSNGSALLGNLLSIKPILRF-DEEGKIVVYEKVRTEKKAMKRLVEILN.DLIAD..---
   6 LVKGGRLSNGSALLGNLLSIKPILRF-DEEGKIVVYEKVRTEKKAMKRLVEILN.DLIAD..---
   7 LQRGGRLNGAQALVGSLLQIKPILHF--NDKQIVLFEKVRTQKKALKRIEDILE.VAIKN..---
   8 LQRGGRLSGAQAFVGSLLKVKPILHF--ENKLIVPYEKIRTRKKAMNRLFELFG.EDAEK..---
   9 LQKSGRITGAQAWVGTLLKMKPVLKF--EDGKIIPEEKVRTKKRAIQTLEKKVL.DIVKD..---
  10 LQKSGRITGAQAWVGTLLKMKPVLKF--EDGKIIPEEKVRTKKRAIQTLEKKVL.DIVKD..---
  11 LVKGGRLSNGAAILGNLLSIKPILYF-NDQGVIEVYEKVRTEKKATKRLIEIIK.ETTAS..---
  12 LVRGGRLSKVAGFIGGLLNIKPILNV--EEGKLVPLEKVRGKKKVLSRIVDIME.ERGKE..---
  13 LVKGGRLSNGAAILGNLLSIKPILYF-NDQGVIEVYEKVRTEKKATKRLIEIIK.ETTAS..---
  14 LYRGGRLSRTQSIIGGILNVKPILTN--EDGELKVIDKVRGQKKAIRWIIDYMK.NTGID..---
  15 LKRGGRISSTAAAIGSLLSIKPMLYV-NDAGELHNFAKAKGRKKSLKMLFQELE.KRIVN..---
  16 LHRGGRLNAAQLVVGSLLKIKPILHF--EDGSIVPLEKVRTEKKAWARVKELFA.EEASS..---
  17 LIKGGRVGRMQGFLGSLLNIKLIAKL--TDGQLEEETKVRSNKKVLQYCLNLIK.DEPKK..---
  18 LQRGGRLNGAQALVGSLLQIKPILHF--NDKQIVLFEKVRTQKKALKRIEDILQ.KAVQN..---
  19 LARGGRISKTSAFVGGLLNIKPLLQM--EDGKLVPLEKIRGQKKLFKRIIELMK.ERGDD..---
  20 LVKGGRISRVTGLLSSLLNIRAVMQM--KDHELQPMVKGRGTKTFKKWLDELIT.SLSER..---
  21 LVAGGRLSNLKSFIIKSLKFHLLISFLGENGKLQFFDKARSAHDAHKLAVKFLK.KQLLK..HSA
  22 LIKGGRVGRMQGFLGSLLNIKLIAKL--TDGQLEEETKVRSNKKVLQYCLNLIK.DEPKK..---
  23 LVKGGRIGKGKAFIGSLLNIKPIASL--EDGVYNPVTKVRSQGQIVKTLAKLFE.EDTAG..---
  24 LVAGGRLSNLKSFIIKSFKFHLLISFLGETGKLQFFNKAQSASSAHKLAVQFLE.KKLLK..KEV
  25 LIKGGRISKTKGLIGNLMKIKPIGTL--DDGRLELVHNARTQNSSIQYLKKEIA.EFIGD..---
  26 LIKGGRIGKVSGTVGQLLDIKPIISI-NEEGVYYTHCKAKGKKQAIKKLIEILR.RTLSE..---
  27 LIKGGRISKTKGLIGNLMKIKPIGTL--DDGRLELVHNARTQNSSIQYLKKEIA.EFIGD..---
  28 LVKGGRIGRVTGVLSSLLNVKVVMAL--KNDELKTLVKGRGNKTFTKWLDSYLA.KNSHR..---
  29 LVKGGRIGRVTGVLSSLLNVKVVMAL--KNDELKTLVKGRGNKTFTKWLDSYLA.KNSHR..---
  30 LVKGGRVSKFQGFVGNLLKIRVCLHI--ENGELIPYRKVRGDKKAIEALIEKLR.EDTPE..---
  31 LVKNGRLSKLVGKVIGLLNIRMVGKA-SNKGTLELLQKARGQKKAVSALIEEIQ.KE---..---
  32 LMRGGRLSKGSAFLGSLASIKPLLWI-DEEGKLVPIAKIRGRQKAIKEMVAQVE.KDIAD..---
  33 LVKNGRLSKLVGKVIGLLNIRMVGKA-SNKGTLELLQKARGQKKAVSALIEEIQ.KE---..---
  34 MRKGGRISGLKKFITTLLRVKPIILF--DKGVNTLGAKVFSFSQAVEKIFGFVKtKFGDN..YKI
  35 LRRGGRIGKVAGTVGDLLHLKPIISV-DEHGAYTTIAKARGRKQSLKKLASIIL.EHLDE..---
  36 LAKGGRLSNGAAVLGTLLNIKPVLTF-STEGKVEVFEKVRTVKKTMSRMKELLL.KDAKD..---
  37 LMRGGRLSKGSAFLGSLASIKPLLWI-DEEGKLVPIAKIRGRQKAIKEMVAQVE.KDIAD..---
  38 LRKGGRISGLKKIIATLLRVKPIIFF--DKGVNTLSGKAFTFVQALEKIFTFVKsKFGDN..FKI
  39 LVKGGRIGRVTGLLSSLLNIRVVMQM--KDHELQPMVKGRGTKTFKKWLDELIT.SLSER..---
  40 MVQSGRIPRVLGKLAQKLSLYPIVSL-DESGDGKLIGVSFSQKQSMKKIIKKIA.KLQLK..---
  41 LVKNGRLSKLVGTVVGLLNIRMVGEA-SAEGKLELLQKARGHKKSVTAAFEEMK.KA---..---
  42 LRLNGRIGGASALLGGLLNIKPLLVV--RGGRVDAGGRVRGQKKALADLAEHVR.RYVSQ..H--
  43 LYASGRVKGVQFLLGSLLSVNLILEV--KGGELLLEKKVRKIQKCREYIKNELE.KELPK..---
  44 LKKGGRIGKIAGTIGKLLNIKPIVSV-DDNGVYYAYDKVRGRKQSLNRVMEIAK.DITKN..---
  45 LKKGGRIGGAGALIGNLLKIIPILTV--EDGKTSVFAKIRTKKRAVETMVQRVL.EDTDK..FGM
  46 LVKNGRLSKLVGKVIGLLNIRMVGKA-SNKGTLELLQKARGQKKAVSALIEEIQ.KE---..---
  47 LVRGGRLSKGKALFVSALGIKLMLNV--LDGEMNVQGKIRGTKKMVKAMIEQFD.SIPKK..---
  48 MVESGRIPRILGRLAQKLSLYPIVSL-DRNGEGKLIGVSFSQKQSMKKVIKKVA.KLQLK..---
  49 LVAGGRLSPKAAALAKVLKVVPIIKF--ENGELLKEGKGISFQKTLTKLISSLS.GKYSK..---
  50 IYKGGRISKSQYMMSNLLNIKVIMTM--KDGQVVAREKVRGRKKAIKYIIDYIE.KNEST..---
  51 LVKNGRLSKLIGTVVGLLNIRMVGKA-SETGTLELLQKARGSKKSVQAAYDELV.KA---..---
  52 LVKGGRISGVKKFILTKLKLFPIIQS---YTNNSIAGLKRTFKSSLEKIYNKLA.EFIGG..-EN
  53 LIAGGRVKKTKGIIAKALRLKLIVRW---NGQLDFMDKTPNLSTAIDKLLDIID.NQNHW..RTN
  54 MINSGRIPKILGETAQKLSMHPIISL-DKRGNGKLIGASFSQNKSMDKILKKIN.LLSKE..---
  55 LVRSGRIPKIIGTMLKLSKVTPIIKA---EWKNHRAGMALNIRSAPHKILENIN.HVFDNqlNNH
  56 LMKSGRVKAITGMLGNLIKIHPILSI--EDGELRVVAKKRGLKNVVEKIVQDLK.ID---..---


      80       190       200         210       220        230       
      |         |         |           |         |          |       
   1 KLKRGAFLTTVFDEQTNTNLVQEFD..KLLDHSINIEQSLLSPVIC.THTGLNSYVIVLQGE
   2 GLPMRAAVIHANREEEAAKIIEELS..AKYPH-VEFYNSYFGAVIG.THLGEGALGICW---
   3 GVPMEAVIIHAQREEEANEWKKELE..AKYPH-VTIRTGYFGAVIG.THLGEGALGLGWY--
   4 --GQYNVSIIHSKAQDKADYLKRLL..QDSGYQYDIEEVHFGAVIA.THLGEGAIAFG----
   5 --GQYNVFIIHSKAQDKADYLKRLL..QDSGYQYDIEEVHFGAVIA.THLGEGAIAFG----
   6 --GQYNVSIIHSKAQDKADYLKRLL..QDSGYQYDIEEVHFGAVIA.THLGEGAIAFG----
   7 KNAEKAYVIHGNDPEKGETWRKHLE..SKFPE-VEFELSYFGPVIG.THLGEGALGLTW---
   8 GKPLRAVVIHANREEEADQIIEELS..KQYAH-VEFYKSYFGPVIG.THLGEGAMGIAW---
   9 FEEVTLFVINGDHFEDGQALYKKLQ..EDCPSGYQVAYSEFGPVVA.AHLGSGGLGLGYV--
  10 FEEVTLFVINGDHFEDGQALYKKLQ..DDCPSAYQVAYSEFGPVVA.AHLGSGGLGLGYV--
  11 -GQYRVIVIHGNAPEKAEELRQHLL..DFGLG-SDVSLATFGSVIG.THLGAGSIALGY---
  12 -LKGQTIGMTHGDDLETAEALKALI..TERFGCEVFIVNTIGAAIG.AHTGPGVITLFFLNE
  13 -GQYRVIVIHGNAPEKAEELRQHLL..DFGLG-SDVSLATFGSVIG.THLGAGSIALGY---
  14 -FAEREVGLIHTDKEEFLNEIEAAL..RSELEITRFIRSQAGCGIG.THAGPDAAGVFF---
  15 -PNEQTIFIAHSDCVEDAETLAEMI..REKYPVKDILIDYIGIVIG.SHTGIGTLAVFFLGD
  16 ASSVKATVIHANRLDGAEKLADEIR..SQFSH-VDVSISHFGPVIG.THLGEGSIGLSWYIE
  17 ---IQQLDVVHANGLNLADDFIAES..KEITGLTEIPLFFADPVIS.THAGTGAFAFMYYTD
  18 KTAEKAYVIHGNDLAKGEAWLAQLE..AKFPE-VTFELSYFGPVIG.THLGEGALGLTW---
  19 -WSNQTVGISYAANKEKATDMKHLI..EEAFKPKEIIMHPISSAIG.SHAGPGTLAIFF---
  20 --AVAEIGISYSGSDDWAKEMKESL..QAYVE-KPISVLETGSIIQ.THTGENAWAILI---
  21 KLKRGAFLTTVFDEQTNTNLVQEFD..KLLDHSINIEQSLLSPVIC.THTGLNSYVIVLQGE
  22 ---IQHLDVVHANGLNLADDFIAES..KEITGLTEIPLFFADPVIS.THAGTGAFAFMYYTD
  23 -KVVKAVAIPHAKAIPLAENVKAAV..EKVSGFAQSEIFFTTPIIS.THTGPGAIGFMYLA-
  24 NFRRAALLTTMFETDKNQLIKQEFV..TLLNNAVDVSEHLLSPVIC.THTGINSYAFLIQTE
  25 -HEIKSIGVAHANVIEYVDKLKKVF..NEAFHVNNYDINVTTPVIS.AHTGQGAIGLVV---
  26 --KHCDIWVMHGGAYDEIDKLKDLV..SGIENINNLNSGEISPVAG.VHTGPGLLGVVI---
  27 -HEIKSIGVAHANVIEYVDKLKKVF..NEAFHVNNYDINVTTPVIS.AHTGQGAIGLVV---
  28 --PIAEIAISYAGEASLALTLKERI..AAYYN-HSISVLETGSIIQ.THTGEGAFAVMVRY-
  29 --PIAEIAISYAGEASLALTLKERI..AAYYN-HSISVLETGSIIQ.THTGEGAFAVMVRY-
  30 GSKLRVIGVHADNEAGVVELLNTLR..KSYEV-VDEIISPMGKVIT.THVGPGTVGFG----
  31 GYVGGKVYIAHAQNPKICEQISEKI..KSLYPDAVIQTGRTSGLCS.FYAEDGGLLMGY---
  32 ---STVIVSYTSDQGSAEKLREELL..AHENI-SDVLMMPLGPVIS.AHVGPNTLAVFVI--
  33 GYVGGKVYIAHAQNPKICEQISEKI..KSLYPDAVIQTGRTSGLCS.FYAEDGGLLMGY---
  34 KRIGFCYSFCKNYANEIKKIITDFIehNKINFQNEIENAFITSVII.VHTGIDAFSISLLID
  35 -GKCNVAILNGMAEEEANQVLDSIS..SHPNL-LKSQVRAIGAAMG.VHAGPGMVGVSIQK-
  36 PLAYKVYVIHTRAEDRAQELYDYAL..SQGFD--DVEIVTFGPVIA.THLGLNTVA------
  37 ---STVIVSYTSDQGSAEKLREELL..AHENI-SDVLMMPLGPVIS.AHVGPNTLAVFVI--
  38 KRIGFCNAFTPVKAKEVKALILDFLhtNKITLQREIESSFITSAII.AHTGIDAFSISLLLD
  39 --AVAEIGISYSGSDDWAKEMKESL..QAYVE-KPISVLETGSIIQ.THTGENAWAILI---
  40 -----ELAITHVSSRDNAAIWQKQL..EKETG-KISYLVDSSAAIA.ISAGLGSVAV-----
  41 GYDGGRIVMAHRNNAKFFQQFSELV..KASFPTAVIDEVATSGLCS.FYAEEGGLLMGY---
  42 GGARVAFLATVGGEEDRAAVRAQLS..DLHF--QDMGDHEIGAVVT.VHAGPGAVGV-----
  43 ----VLHMFHANDKDGAEEWIADIR..QAFPE-MDFKLYPLPISFA.VHAGEGTIAIS----
  44 -SKCRAYVMHGDAEKESKEFFKKVK..ELPNINNAFYNGCISPVSG.VHSGPGLVGLVLLE-
  45 GG----IAVHHINCYDEAKRLAETI..KNKFK-VDPIICDIGPVIG.LHVGPGAIGIAYYTE
  46 GYVGGKVYIAHAQNPKICEQISEKI..KSLYPDAVIQTGRTSGLCS.FYAEDGGLLMGY---
  47 --EGEPIILVELENEDIYLPIKEYL..ENNN--IEYLKLPLGCSVA.IHSGPKVCALFYVEE
  48 -----ELAITHVSSERDAKLWQKEL..EAKIG-GNSYLVDSSAAIA.ISAGLSSVAV-----
  49 DSKNYFPVILHAQNSNISFYEEHFL..NEFG--KKPLILSLPSVIS.VHTGLGAIAISL---
  50 -LDGRVIGMNHANDKSYLEELKEAV..LSKYIPSETIYSEVGCTVA.AYSGLSAVALYY---
  51 GYAGGRIVMAQRNNEKCCQQLSERI..RETFPQADIKILPTSGLCS.FYAEEGGLLMGYEI-
  52 NFKNYNLKLVHGPSKEMVDGAVEFF..KQKGL-EFSSIVLASTVII.AHTGPDSISISV---
  53 GIKNIAILTDLENESQINSLKTSLQ..EKIRQTIEIKISYLPGCIY.AHVGLNNFAIL----
  54 -GQIEELALTHVLSEESALKINELL..KEKTT-KNCEIIDSSAAIG.ISAGIGSLAI-----
  55 TIEKVCILQAGLSSERIDELKNDVI..NHFHVDKEKIVIRSGPPIFlVYVWKGALGI-----
  56 GRKMLGLVYAGEEMKEIVLEIEEKL..KDEHI-ERVDIVRLPPTLA.VHSGPKMFG------