PFRMAT SS TARGET T0193 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0193.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0193.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0193.t2k.str.rdb (weight 1.53983) METHOD T0193.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0193.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0193 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0193.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 18 METHOD METHOD ============================================ METHOD Comments from T0193.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0193 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0193.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 18 METHOD METHOD ============================================ METHOD Comments from T0193.t2k.str.rdb METHOD ============================================ METHOD TARGET T0193 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0193.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 18 METHOD METHOD ============================================ METHOD Comments from T0193.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0193 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0193.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 18 METHOD METHOD ============================================ MODEL 1 M C 0.86 K C 0.80 V C 0.79 P C 0.75 E H 0.87 A H 0.90 A H 0.90 I H 0.91 S H 0.86 R H 0.81 L H 0.77 I H 0.91 T H 0.94 Y H 0.95 L H 0.95 R H 0.96 I H 0.95 L H 0.95 E H 0.95 E H 0.94 L H 0.93 E H 0.90 A H 0.80 Q C 0.62 G C 0.93 V C 0.87 H C 0.61 R E 0.60 T E 0.57 S C 0.68 S H 0.74 E H 0.92 Q H 0.93 L H 0.94 G H 0.94 E H 0.92 L H 0.87 A H 0.57 Q C 0.89 V C 0.90 T C 0.92 A H 0.88 F H 0.93 Q H 0.92 V H 0.93 R H 0.89 K H 0.88 D H 0.79 L H 0.80 S H 0.78 Y H 0.68 F H 0.50 G C 0.57 S C 0.57 Y C 0.71 G C 0.82 T C 0.79 R C 0.66 G C 0.68 V C 0.63 G C 0.60 Y C 0.55 T C 0.64 V H 0.90 P H 0.95 V H 0.95 L H 0.95 K H 0.95 R H 0.95 E H 0.95 L H 0.95 R H 0.95 H H 0.93 I H 0.87 L H 0.52 G C 0.88 L C 0.83 N C 0.81 R C 0.70 K C 0.59 W E 0.52 G E 0.69 L E 0.90 C E 0.93 I E 0.93 V E 0.86 G E 0.71 M C 0.72 G C 0.80 R H 0.62 L H 0.89 G H 0.93 S H 0.93 A H 0.93 L H 0.89 A H 0.79 D H 0.58 Y C 0.59 P C 0.58 G C 0.61 F C 0.67 G C 0.78 E C 0.83 S C 0.82 F E 0.58 E E 0.86 L E 0.92 R E 0.88 G E 0.90 F E 0.88 F E 0.84 D E 0.69 V C 0.62 D C 0.79 P C 0.62 E C 0.65 K C 0.52 V C 0.66 G C 0.62 R E 0.64 P E 0.69 V C 0.51 R C 0.86 G C 0.89 G C 0.50 V E 0.75 I E 0.74 E E 0.59 H C 0.64 V H 0.66 D H 0.80 L H 0.81 L H 0.82 P H 0.81 Q H 0.80 R H 0.74 V H 0.55 P C 0.57 G C 0.77 R C 0.89 I C 0.81 E E 0.54 I E 0.92 A E 0.93 L E 0.93 L E 0.88 T E 0.70 V C 0.69 P C 0.87 R H 0.70 E H 0.87 A H 0.91 A H 0.93 Q H 0.94 K H 0.94 A H 0.95 A H 0.96 D H 0.96 L H 0.96 L H 0.96 V H 0.95 A H 0.92 A C 0.53 G C 0.93 I C 0.89 K C 0.70 G E 0.78 I E 0.89 L E 0.86 N E 0.67 F C 0.68 A C 0.75 P C 0.63 V E 0.58 V E 0.73 L E 0.58 E E 0.54 V C 0.63 P C 0.81 K C 0.84 E C 0.84 V C 0.50 A E 0.85 V E 0.89 E E 0.81 N E 0.79 V E 0.62 D C 0.61 F H 0.49 L H 0.61 A H 0.76 G H 0.84 L H 0.91 T H 0.95 R H 0.95 L H 0.96 S H 0.96 F H 0.95 A H 0.93 I H 0.83 L H 0.56 N C 0.74 P H 0.73 K H 0.80 W H 0.84 R H 0.84 E H 0.80 E H 0.76 M H 0.57 M C 0.63 G C 0.92 END