PFRMAT SS TARGET T0192 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0192.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0192.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0192.t2k.str.rdb (weight 1.53983) METHOD T0192.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0192.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0192 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0192.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 291 METHOD METHOD ============================================ METHOD Comments from T0192.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0192 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0192.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 291 METHOD METHOD ============================================ METHOD Comments from T0192.t2k.str.rdb METHOD ============================================ METHOD TARGET T0192 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0192.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 291 METHOD METHOD ============================================ METHOD Comments from T0192.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0192 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0192.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 291 METHOD METHOD ============================================ MODEL 1 M C 0.90 A C 0.80 K C 0.55 F E 0.75 V E 0.84 I E 0.77 R E 0.57 P C 0.60 A C 0.84 T C 0.90 A H 0.64 A H 0.65 D H 0.67 C H 0.91 S H 0.93 D H 0.94 I H 0.95 L H 0.96 R H 0.95 L H 0.95 I H 0.94 K H 0.92 E H 0.87 L H 0.80 A H 0.68 K H 0.66 Y H 0.61 E H 0.51 Y C 0.51 M C 0.54 E C 0.53 E C 0.52 Q C 0.50 V H 0.51 I H 0.60 L H 0.67 T H 0.69 E H 0.83 K H 0.87 D H 0.87 L H 0.87 L H 0.88 E H 0.86 D H 0.83 G H 0.77 F H 0.68 G H 0.52 E C 0.61 H C 0.77 P C 0.76 F C 0.73 Y C 0.60 H E 0.55 C E 0.80 L E 0.85 V E 0.83 A E 0.77 E E 0.62 V C 0.46 P C 0.52 K C 0.47 E E 0.43 H E 0.53 W E 0.58 T E 0.57 P C 0.42 E C 0.58 G C 0.86 H C 0.88 S E 0.62 I E 0.87 V E 0.86 G E 0.92 F E 0.93 A E 0.92 M E 0.92 Y E 0.89 Y E 0.86 F E 0.77 T E 0.49 Y C 0.65 D C 0.72 P C 0.73 W C 0.73 I C 0.75 G C 0.79 K C 0.74 L E 0.54 L E 0.70 Y E 0.83 L E 0.85 E E 0.79 D E 0.83 F E 0.84 F E 0.88 V E 0.81 M C 0.61 S H 0.68 D H 0.66 Y H 0.70 R C 0.57 G C 0.75 F C 0.74 G C 0.71 I H 0.61 G H 0.84 S H 0.95 E H 0.96 I H 0.96 L H 0.96 K H 0.96 N H 0.96 L H 0.96 S H 0.96 Q H 0.96 V H 0.96 A H 0.95 M H 0.94 R H 0.83 C C 0.72 R C 0.94 C C 0.89 S C 0.67 S E 0.86 M E 0.92 H E 0.93 F E 0.90 L E 0.84 V E 0.69 A C 0.56 E C 0.70 W C 0.79 N C 0.78 E H 0.68 P H 0.84 S H 0.93 I H 0.95 N H 0.95 F H 0.96 Y H 0.95 K H 0.93 R H 0.84 R C 0.52 G C 0.91 A C 0.77 S E 0.60 D E 0.67 L E 0.60 S E 0.51 S E 0.53 E E 0.51 E C 0.54 G C 0.62 W C 0.46 R C 0.43 L C 0.57 F C 0.70 K C 0.78 I C 0.80 D C 0.79 K H 0.88 E H 0.93 Y H 0.94 L H 0.94 L H 0.94 K H 0.92 M H 0.88 A H 0.77 T H 0.55 E C 0.63 E C 0.87 END