PFRMAT SS TARGET T0191 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0191.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0191.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0191.t2k.str.rdb (weight 1.53983) METHOD T0191.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0191.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0191 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0191.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ METHOD Comments from T0191.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0191 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0191.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ METHOD Comments from T0191.t2k.str.rdb METHOD ============================================ METHOD TARGET T0191 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0191.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ METHOD Comments from T0191.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0191 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0191.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ MODEL 1 I C 0.86 G C 0.80 Y C 0.74 N C 0.63 T C 0.49 D H 0.75 G H 0.91 I H 0.95 G H 0.95 A H 0.96 R H 0.96 M H 0.95 A H 0.95 L H 0.94 E H 0.91 E H 0.82 E H 0.54 I C 0.81 G C 0.81 R C 0.78 V C 0.70 K C 0.76 D C 0.85 K C 0.71 N E 0.79 I E 0.93 V E 0.93 I E 0.92 Y E 0.79 G C 0.62 A C 0.84 G C 0.62 G H 0.90 A H 0.94 A H 0.96 R H 0.96 A H 0.96 V H 0.96 A H 0.96 F H 0.95 E H 0.93 L H 0.89 A H 0.76 K C 0.57 D C 0.90 N C 0.86 N C 0.57 I E 0.88 I E 0.92 I E 0.92 A E 0.85 N E 0.63 R C 0.82 T C 0.88 V H 0.85 E H 0.91 K H 0.93 A H 0.95 E H 0.95 A H 0.95 L H 0.95 A H 0.94 K H 0.91 E H 0.86 I H 0.73 A H 0.53 E C 0.51 K C 0.59 L C 0.72 N C 0.72 K C 0.60 K C 0.53 F C 0.48 G C 0.54 E E 0.49 E E 0.51 V C 0.61 K C 0.79 F H 0.60 S H 0.66 G H 0.73 L H 0.80 D H 0.86 V H 0.85 D H 0.80 L H 0.75 D H 0.52 G C 0.73 V C 0.84 D C 0.81 I E 0.90 I E 0.93 I E 0.93 N E 0.88 A C 0.50 T C 0.77 P C 0.80 I C 0.78 G C 0.81 M C 0.80 Y C 0.78 P C 0.76 N C 0.78 I C 0.72 D C 0.74 V C 0.70 E C 0.69 P C 0.68 I C 0.60 V C 0.60 K C 0.59 A H 0.73 E H 0.70 K H 0.62 L C 0.54 R C 0.76 E C 0.82 D C 0.84 M C 0.58 V E 0.86 V E 0.91 M E 0.90 D E 0.86 L E 0.69 I E 0.48 Y C 0.74 N C 0.86 P C 0.81 L C 0.81 E C 0.73 T C 0.59 V H 0.82 L H 0.88 L H 0.92 K H 0.93 E H 0.94 A H 0.94 K H 0.92 K H 0.84 V C 0.61 N C 0.92 A C 0.79 K E 0.65 T E 0.64 I C 0.53 N C 0.74 G C 0.62 L H 0.83 G H 0.89 M H 0.91 L H 0.89 I H 0.89 Y H 0.90 Q H 0.90 G H 0.87 A H 0.84 V H 0.76 A H 0.58 F C 0.63 K C 0.89 END