Citations (SAM, SAM-T99, HMMs)
10 20 30 40 50 | | | | | 1 MVLTVTLNPALDREIF..IEDFQ..VNRL.....YRINDLSKTQMSPGGKGINVSIALSK.L... 2 -LVVCFGEMLIDFVPT..VGGVS..LAEA.....------PAFKKAPGGAPANVAVGVSR.L... 3 -LVVCFGEMLIDFIPT..VAGVS..LAEA.....------PAFEKAPGGAPANVAVCISK.L... 4 -LVVSFGEMLIDFVPT..VAGVS..LAEA.....------PAFVKAPGGAPANVAIAVAR.L... 5 -VATITLNPAYDLVGF..CPEIE..RGEV.....NLV---KTTGLHAAGKGINVAKVLKD.L... 6 -LIVSFGEMLIDFVPT..VSGVS..LSES.....------PGFLKAPGGAPANVAIAVSR.L... 7 -KVLVVGSLNMDLVVR..APRLPr.GGET.....LAG---QSFITVPGGKGANQAVAAAR.L... 8 -VATITLNPAYDLVGF..CPEIE..RGEV.....NLV---KTTGLHAAGKGINVAKVLKD.L... 9 -LIVSFGEMLIDFVPT..ESGVS..LAEA.....------PGFLKAPGGAPANVAIAVSR.L... 10 -LIVSFGEMLIDFVPT..ESGVS..LAEA.....------PGFLKAPGGAPANVAIAVSR.L... 11 -VVTITLNAAYDLVGR..LNRIQ..LGEV.....NTV---ETLGLFPAGKGINVAKVLKD.L... 12 -KLVVLGSINADHILN..IEQFPr.PGET.....VIG---QQYNVAFGGKGANQAVAAGR.S... 13 MITTVTANPAIDRTVI..VENLR..LGSV.....NRV---IRSRVDAGGKGINVAKNLKN.L... 14 KKIGVVGSNMVDLITY..VDRMPg.PGET.....LEA---PTFEMGCGGKGANQAVAAAR.L... 15 -TLTVLGSINADHVIS..VPYFTk.PGET.....LTG---QNYQIAYGGKGANQAVAAAR.L... 16 -KIVVFGSIVQDLVSY..TDSFPr.PGES.....VRG---HNFKLGSGGKGANQAVAAAR.L... 17 PYVVCFGEMLIDFVPT..TSGLS..LADA.....------PAFKKAPGGAPANVAVGIAR.L... 18 MIYTVTLNPSVDYIVH..VEDFT..VGGL.....NRS---SYDTKYPGGKGINVSRLLKR.H... 19 MSIIVFGSINIDLVAT..APKLPg.AGET.....LLG---EDFFKVPGGKGANQAVALAR.L... 20 NKICVLGSMNMDLVLK..VKDMPk.VGET.....ILS---KSFQKIAGGKGANQAVAAKR.S... 21 -RVWLTGDAVVDLIPD..GQ---..----.....------QHYLKCPGGAPANVAVAIAR.L... 22 -VATITLNPAYDLVGF..CPEIE..RGEV.....NLV---KTAGLHAAGKGINVAKVLKD.L... 23 FDLIAVGRLCVDLNAN..ETQRP..MEET.....------RTFTKYVGGSPANIAIGAAR.L... 24 KVLTITLNSAYDLVGH..LPHLT..RGAV.....NQV---DSLGLYPAGKGINVGKVLHD.L... 25 FDLIAIGRACIDLNAV..EYNRP..MEET.....------MTFSKYVGGSPANIVIGSSK.L... 26 MIYSVTLNPSIDFIVR..VKDFQ..LGET.....NRA---YEDNFFAGGKGIMVSKLLKN.V... 27 MVITVTLNPAMDKTLN..IDNFN..VGVV.....NRV---SNIRYDIGGKGINVSKVLKN.F... 28 MDIAVIGSNMVDLITY..TNQMPk.EGET.....LEA---PAFKIGCGGKGANQAVAAAK.L... 29 -LIVSFGEMLIDFVPD..TSGVS..LAES.....------TGFLKAPGGAPANVACAITK.L... 30 FDIVPVGRVAIDFNPT..DIHKP..LSES.....------RNFNKYLGGSPANIAVGLAR.L... 31 FDIVAIGRACIDLNAV..EYNRP..MEET.....------MTFSKYVGGSPANIAIGSAK.L... 32 NKVWVIGDASVDLVPE..KQ---..----.....------NSYLKCPGGASANVGVCVAR.L... 33 MDIAVIGSNMVDLITY..TNQMPk.EGET.....LEA---PAFKIGCGGKGANQAVAAAK.L... 34 KRIWVLGDAVVDLLPG..QD---..----.....------NLLLKCPGGAPANVAVGIAR.L... 35 RIYTLTLAPSLDSATI..TPQIY..PEGK.....LRC---TAPVFEPGGGGINVARAIAH.L... 36 RIYTLTLAPSLDSATI..TPQIY..PEGK.....LRC---TAPVFEPGGGGINVARAIAH.L... 37 -GVMVVGDVMLDRYWY..GPTSRisPEAP.....VPVVKVNTIEERPGGAA-NVAMNIAS.L... 38 -GVMVVGDVMLDRYWY..GPSSRisPEAP.....VPVVKVNTIEERPGGAA-NVAMNIAS.L... 39 --AVAVGHALVDLRLY..VERIPg.VDEE.....AVI---KDETRSVGGSAANVAVVLRR.L... 40 -GVMVVGDVMLDRYWY..GPTCRisPEAP.....VPVVKVNTVEERPGGAA-NVAMNIAS.L... 41 MILTVTLNPAIDVSYP..LDELK..CDTV.....NRV---VDVTKTPGGKGLNVCRVLND.F... 42 -GVMVVGDVMLDRYWY..GPTCRisPEAP.....VPVVKVNTVEERPGGAA-NVAMNIAS.L... 43 -GVMVVGDVMLDRYWY..GPTCRisPEAP.....VPVVKVNTVEERPGGAA-NVAMNIAS.L... 44 MIYTITLNPSIDYIVQ..IDQLK..LGEL.....NRM---KQDYKLPGGKGINVSRVLNQ.L... 45 RIYTLTLAPSLDSATI..TPQIY..PEGK.....LRC---SAPVFEPGGGGINVARAIAH.L... 46 RIYTLTLAPSLDSATI..TPQIY..PEGK.....LRC---SAPVFEPGGGGINVARAIAH.L... 47 NLVVSFGEMLIDFVPD..VAGVS..LAES.....------GGFVKAPGGAPANVACAISK.L... 48 FDLITVGRACIDLNAV..EYNRP..MEET.....------MTFSKYVGGSPANIAIGTAK.L... 49 RKIVVVGSINMDIVIR..VPRIPv.VGET.....VIA---YDLKNYGGGKGANQAVSIAR.L... 50 NKVFCIGELLIDFIGK..DIGKG..LKNG.....------VNFEKKAGGAPANVGAAVCK.L... 51 MIVASIGNLNFDIYLK..VSELPg.PDEN.....VEA---LDLYTGGGGSAANFAVAIAK.M... 52 MIYTITLNPSIDYIVQ..IDQLN..LGGL.....NRM---KQDYKLPGGKGINVSRVLNQ.L... 53 FDLITVGRACIDLNAV..EYNRP..MEET.....------MTFSKYVGGSPANIAIGTAK.L... 54 -DLITIGRASVDLYGQ..QIGTR..LEDV.....------ASFAKSVGGCPCNISVGTAR.L... 55 RIVTVTLNPAIDMTVG..LDRLE..RGHV.....NLG---RSVTHQAGGKGVNVAGCLAD.W... 56 -KIWVLGDAVVDLIPE..GE---..----.....------NTYLRCAGGAPANVAVGIAR.L... 57 MIYTVTLNPSIDFIVR..IDQIN..LGSV.....NRM---ASDDKFAGGKGINVSRILQR.L... 58 -AITVTLNPAIDQTIQ..LDRLQ..PGAV.....HRA---SSVRNDAGGKGINVAACLAD.W... 59 LDLITIGRSSVDLYGS..QVGGR..LEDM.....------ASFAKYIGGSPTNIAAGAAR.L... 60 -AVVVVGSCMTDLVSL..TSRLPk.TGET.....IHG---HEFFIGFGGKGANQCVQAAR.L... 61 MIYTLTLNPSIDYVID..VENLE..LGKV.....NRT---SNDFKFPGGKGINVSRILGN.Q... 62 RVLTLTLNPALDLTVR..ADGWR..PNTV.....NSG---QTLHLTAGGKGVNVASFLAD.W... 63 -AVVVVGSCMTDLVSL..TSRLPk.TGET.....IHG---HKFFIGFGGKGANQCVQAAR.L... 64 -KVWVLGDAVVDLLPE..SE---..----.....------GRLLQCPGGAPANVAVGVAR.L... 65 -MIVVVGSINLDLIAK..VDRLPs.PGET.....VRG---SGFSTAPGGKGANQALAAAR.A... 66 MIYTVTLNPSIDYIVR..LDQVK..VGSV.....NRM---DSDDKFAGGKGINVSRVLKR.L... 67 MIYTVTLNPSIDYIVR..LDQVK..VGSV.....NRM---DSDDKFAGGKGINVSRVLKR.L... 68 MMLTVTMNPSIDIAYQ..LDDLK..VDTV.....NRV---IETHKTPGGKGLNVTRVLSQ.L... 69 MIYTVTLNPALDYFMN..YEELA..LGEV.....NRT---GKTQISAGGKGIMESRMLSL.V... 70 MIYTVTLNPSIDFIVR..IDQIN..LGSV.....NRM---ASDDKFAGGKGINVSRILQR.L... 71 RIYTLTLAPSLDSATI..TPQIY..PEGK.....LRC---TAPVFEPGGGGINVARAIAH.L... 72 NQVWVTGDAVVDLIPE..SE---..----.....------TSLLKCPGGAPANVAVAIAR.L... 73 MILTVTLNPAIDVSYP..LDELK..CDTV.....NRV---VDVTKTPGGKGLNVSRVLNE.F... 74 -VATITLNPAYDLVGF..CPEIE..RGEV.....NLV---KTTGLHAAGKGINVAKVLKD.L... 75 --LMFFGTTNLDLCFN..VERLP..TPGE.....SLM---GSLKQNAGGKGANQAVAAAR.L... 76 LKIFVFGSVNVDVSAR..MAALPr.PEQT.....VNA---SGYGIGLGGKGANQAVAVAK.L... 77 NVLFGMGNPLLDISAV..VDKDF..LDKYs18lfDELVKKFKVEYHAGGSTQNSMKVAQW.Miqe 78 MIYTVTLNPSIDFIVR..IDSVK..IGSV.....NRM---DSDDKFVGGKGINVSRILKR.L... 79 ADVLVVGSLNMDLVIR..TPCLPr.PGQT.....VAA---PALETIPGGKGANQAVASAR.L... 80 MNVLCTGEILIDFISE..DKGKN..LSQS.....------ELFRKKAGGSPLNVAVALKR.L... 81 MIYTLTLNPSVDYKIV..LKEFQ..EESL.....NYA---LNNNFFAGGKGINVSTVLKN.L... 82 MITIVNLNASVDKRYE..IGDIV..KGKV.....MRA---RAVENTAGGKGLHVANVAHI.L... 83 MIYTVTFNPSIDYVIF..TNDFK..IDGL.....NRA---TATYKFAGGKGINVSRVLKT.L... 84 NVLFGMGNPLLDISAV..VDKDF..LDKYs18lfDELVKKFKVEYHAGGSTQNSMKVAQW.Liqe 85 NVLFGMGNPLLDISAV..VDKDF..LDKYs18lfDELVKKFKVEYHAGGSTQNSMKVAQW.Liqe 86 -KVSVIGSISMDLVTR..TNRVPn.AGET.....VFG---EDFAMVPGGKGANQAVAFAR.Ls.. 87 LVISVVGSSNIDIVLK..VDHFTk.PGET.....QKA---IEMNVFPGGKGANQAVTVAK.I... 88 KGVTVIGGANIDIKGK..PYKEL..RQHT.....SNP---GHINIAPGGVGRNIAHNLAQ.L... 89 LDLITIGRSSVDLYGA..QIGGL..LEDM.....------ASFNKYVGGSPTNIATGTAR.L... 90 MILTVTLNPAIDVSYP..LDELK..CDTV.....NRV---VDVTKTPGGKGLNVCRVLNE.F... 91 -KVCVLGSFNIDVSAT..VPWFPq.SGES.....ILA---SQFGFYPGGKGANQALAANN.A... 92 MILTVTLNPSVDISYP..LETLK..IDTV.....NRV---KDVSKTAGGKGLNVTRVLYE.S... 93 -PLVVVGSANADIYVE..IERLPk.EGET.....ISA---KTGQTLAGGKGANQAACGAK.L... 94 -PLVVVGSANADIYVE..IERLPk.EGET.....ISA---KTGQTLAGGKGANQAACGAK.L... 95 NVLFGMGNPLLDISAV..VDKDF..LDKYs21elVRK---FKVEYHAGGSTQNSIKVAQW.Miqk 96 MIYTVTLNPSIDYVVQ..VNSLD..LGAV.....NRA---EKDMKFPGGKGINVSRVLHR.L... 97 -PVVILGVFVADTAYR..ADRQPr.MGET.....ILG---NSFKLGPGGKGSNQAVAAGK.L... 98 RIITLTMNPALDITTS..VDVVR..PTEK.....MRC---GAPRYDPGGGGINVARIVHV.L... 99 -LVLVVGDLILDCYWY..SKNHYmlSEQL.....TPIVPINKIKEQPGGAA-NVAKNIAE.I... 100 NQVVCFGEALIDMLAL..PPAGP..----.....DEA---RTFAQYAGGAPANVAVAVAR.L... 101 KVVTITLNPALDLTGS..VNQLN..VGSV.....SLV---GQSSLHAAGKGVNVAKVLSE.L... 102 MKALTFGEALFDI---..-----..----.....------IKGTVHLGGAPLNLAAHLAK.L... 103 -----MGNPLLDISAV..VDKDF..LDKYs21elVRK---FKVEYHAGGSTQNSIKVAQW.Miqk 104 MIYTVTFNPSIDYVIF..TNDFK..IDGL.....NRA---TATYKFAGGKGINVSRVLKT.L... 105 MIHTLTLNTAIDMNMF..CDPLK..PSAV.....NRT---RHTEYCPNGKGVNVSLILNH.Y... 106 -AITVTLNPATDQTIQ..LDRLQ..PGAV.....HRA---SSVRNDAGGKGINVAACLAD.W... 107 MILTVTMNPSIDISYP..LDELK..IDTV.....NRV---VDVTKTAGGKGLNVTRVLSE.F... 108 MIYTVTLNPSIDYIVQ..VENFQ..QGVV.....NRS---ERDRKQPGGKGINVSRVLKR.L... 109 MIYSLTLNPAIDQVIE..VPNFQ..LGET.....NKA---ISEYEVIGGKGINVAVMLQH.L... 110 NVLFGMGNPLLDISAV..VDKDF..LDKYs18lfDELVKKFKVEYHAGGSTQNSMKVAQW.Miqe 111 MILTLTLNPSVDISYP..LTALK..LDDV.....NRV---QEVSKTAGGKGLNVTRVLAQ.V... 112 RIISVVGHTALDYIID..VENIAg.KNES.....SPV---IDYEEYPGGGAANIAVAIAK.L... 113 MILTVTLNTALDITYR..VPALR..PHAS.....HRV---TEVTERPGGKGLNVARVLAA.L... 114 RGVICLGEALIDFIP-..-----..MDST.....NEI-----YQKSPGGAPANVAVGLAK.L... 115 MILTLTLNPSVDISYP..LTALK..LDDV.....NRV---QEVSKTAGGKGLNVTRVLAQ.V... 116 MILTVTMNPSIDISYP..LDELK..IDTV.....NRV---VDVTKTAGGKGLNVTRVLSE.F... 117 MILTITMNPSIDISYP..LDVLN..LDSV.....NRV---TKVTKTAGGKGLNVTRVLKQ.L... 118 -LVLVVGDLILDCYWY..SKNYYvvLEES.....LPIASINKIKKQPGGAA-NVAKNIAE.I... 119 FDVICMGNLNYDIVFL..MEKFPg.IHEK.....VNA---KGVFTGLGGSAGNTATWLAK.L... 120 MVLTVTLNPALDREIF..IEDFQ..VNRL.....YRINDLSKTQMSPGGKGINVSIALSK.L... 121 VMICSIGELLVDVIAT..EEGDL..----.....KDV---RLFEKHPGGAPANVAVGIAR.L... 122 -RVVAAGHVNWDVTLR..VDALPe.PDGE.....AEI---VSQRRSGGGSAANVACALAG.F... 123 -GVMVVGDVMLDRYWY..GPTCRisPEAP.....VPVVKVNTVEERPGGAA-NVAMNIAS.L... 124 -KIWVLGDAVVDLLPD..GE---..----.....------GRLLQCPGGAPANVAVGVAR.L... 125 MIYTITLNPAIDRLLF..IRGELe.KRKT.....NRV---IKTEFDCGGKGLHVSGVLSK.F... 126 MILTVTPNPSLDRTYE..VPSLD..RGEV.....VRA---TGERVDPGGKGVNVSRAVTA.A... 127 -----MGNPLLDISAV..VDKDF..LDKYs18lfDELVKKFKVEYHAGGSTQNSMKVAQW.Miqe 128 RNICVIGSCSMDLVVT..SDKRPk.AGET.....VLG---TSFQTVPGGKGANQAVAAAR.L... 129 RDLLAVGHTAFDYIIH..LDEFPe.PNTS.....TAI---KRMRNLHGGAAANVALVGSR.L... 130 PYLLVFGASVVDVFGF..SKASY..RPYN.....STP---GHVKISFGGVCRNIAENMAR.V... 131 YDLLVVGSANADLVIG..VERRPa.AGET.....VLG---SDLAVHPGGKGGNQAVAAAR.L... 132 MIYTITLNPAIDRLLF..IQGELe.KRKT.....NRV---KKTEFDCGGKGLHVSGVLSK.F... 133 YDVLTIGNAIVDIIAR..CDDSF..LEENg16aeLLYSRMGPAVEASGGSAGNTAAGVAS.L... 134 IDLACLGRVAVDLYAQ..QIGSR..LEDA.....------RSFQMYLGGSSGNVAFGVAR.L... 135 RILTITLNPALDLTVR..LRQLE..LGAV.....NRS---EAVLTQAAGKGLNVAQVLAD.L... 136 ----------------..-----..-K--.....-RISEVDHFKKFLAGAEVNVSVGVSR.L... 137 RIISVVGHTALDYIVD..VENIAg.KNES.....SPV---IDYEEYPGGGAANIAVAIAK.L... 138 -EVVCFGEMLFDCLAD..QLGVP..LEQV.....------KSWTNYAGGAPANVACALVK.Q... 139 -KVLVLGDVMLDRYWFgaTNRIS..PERP.....VPVVRVQENEERAGGAA-NVAMNIAS.L... 140 -YVVIIGSANIDVAGY..SHESL..NYAD.....SNP---GKIKFTPGGVGRNIAQNLAL.L... 141 -NVLCIGELLIDFICS..DIDTT..LSKG.....------ENFKKKAGGAPANVTAAISK.L... 142 -DIVVVGSINADLTAK..VQRHPe.PGET.....LLG---SGGTVSAGGKGANQAVAAAQ.L... 143 -RIACVGITVMDRIYY..VEGLPt.EGGK.....YVA---KRYTEVGGGPAATAAVAAAK.L... 144 --ALTFGEALFDT---..-----..----.....------IKGTAHLGGAPLNLAAHLAK.L... 145 NRIVVVGSINADLNVL..VDRHPa.PGET.....LLG---SGGHITAGGKGANQAVAAAL.Q... 146 IRVACVGITVMDRIYY..VEGLPt.ESGK.....YVA---RNYTEVGGGPAATAAVAAAR.L... 147 -DVSTLGNLCVDIVLS..VHELP..PPSRg11ls--MSPPDKKYWEAGGNC-NMAIAAAR.L... 148 -SVVCIGELLIDFFCT..DVDVD..LMEG.....------RQFLKSAGGAPANVSAAIAK.L... 149 MKVVTFGEIML-----..--RLS..PPDH.....KRIFQTDSFDVTYGGAEANVAAFLAQ.M... 150 IRVACVGITVMDRIYY..VEGLPt.ESGK.....YVA---RNYTEVGGGPAATAAVAAAR.L... 151 IRVACVGITVMDRIYY..VEGLPt.ESGK.....YVA---RNYTEVGGGPAATAAVAAAR.L... 152 RNICVIGSCSMDLVVT..SDKRPk.AGET.....VLG---TSFQTVPGGKGANQAVAAAR.L... 153 -MIASIGELLIDLISV..EEGDL..----.....KDV---RLFEKHPGGAPANVAVGVSR.L... 154 RNVXCIGELLIDFVCR..NTNVSl.-VNG.....------SNFEKKAGGAPANVAAAITK.L... 155 -KITCVGHTALDYIFN..VEKFPe.PNTS.....IQI---PSARKYYGGAAANTAVGIKK.L... 156 VMILCCGEALIDMLPR..QTTLGe.----.....------AGFAPYAGGAVFNTAIALGR.L... 157 -MIVCCGEALIDMLPR..ETTAGe.----.....------SAFAPYAGGAIFNTAVALGR.L... 158 -MILCCGEALIDMLPR..QTTLGe.----.....------AGFAPYAGGAVFNTAIALGR.L... 159 -YVVIIGSANIDVAGY..SHESL..NYAD.....SNP---GKIKFTPGGVGRNIAQNLAL.L... 160 RIATVSLNSAVDQTVT..VPGFT..ADAV.....NRV---AASRIDAGGKGVNVASFLAH.V... 161 -NITVVGSINMDMVTI..TDVVPv.QGET.....VLG---KDFRTVPGGKGANQAVAAAR.L... 162 -KVLVLGDVMLDRYWFgaTNRIS..PEAP.....VPVVRVQENEERAGGAA-NVAMNIAS.L... 163 MIYTLTLNSAIDMNIF..SDPLQ..PNIV.....NRT---HHTEFCPNGKGVNVALVLDH.F... 164 MSALICGSLAYDTIMV..FPDQ-..----.....------FKNHILFGGCAGNIAYNLHL.L... 165 MIYTLTLNSAIDMNIF..SDPLQ..PNIV.....NRT---HHTEFCPNGKGVNVALVLDH.F... 166 -MIIVVGSYNVDVILK..VNKIPe.IGET.....VIA---DELYITHGGKGSNQAVSASR.L... 167 -MITAFGEVLIDFIAA..EE---..-GDL.....ENV---KIFEKHPGGAPANVAVGVSR.L... 168 LDVICMGNLNYDITFM..LERFPe.FHEK.....VNA---KKVYTGLGGSAGNTATWLSF.L... 169 -GIIAAGNMLVDHVHQ..IIQWPe.RGWL.....AEI---THSERSTGGAPLNVLLTLAK.Mrt. 170 MDVVTFGETMV----V..FEPVE..MGAL.....RYV---DRFKKGVGGAESNVAIGVAK.L... 171 -YCVVVGTINMDIRGM..ADIRY..PQSA.....SHP---GTIHCSAGGVGRNIAHNLAL.L... 172 FDVLCIGNAIVDILAR..TDDVF..LETNg16aeLLYSRMGPATEMSGGSAGNTAAGIAS.L... 173 LDVICIGAAIVDIPLQpvSKNIF..DVDS.....YPL---ERIAMTTGGDAINEATIISR.L... 174 LDVITIGRASVDLYGQ..QIGSR..LEDI.....------TSFAKSVGGCPANISVGTAR.L... 175 LDVICIGAAIVDIPLQpvSKNIF..DVDS.....YPL---ERIAMTTGGDAINEATIISR.L... 176 FDVICMGRIAVDLYGQ..QIGAR..LEDV.....------ASFAKYLGGSSGNVAYGSAR.Q... 177 -YCVVVGTINMDIRGM..ADIRY..PQSA.....SHP---GTIHCSAGGVGRNIAHNLAL.L... 178 -KVLVLGDVMLDRYWFgaTNRIS..PEAP.....VPVVRVQDNEERAGGAA-NVAMNIAA.L... 179 WDVLGLGQAMVDFSGV..VDDEF..LKKLg18klLQAMDGCSYKAAAGGSLSNTLVALAR.L... 180 WDVLGLGQAMVDFSGV..VDDEF..LKKLg18klLQAMDGCSYKAAAGGSLSNTLVALAR.L... 181 -YCVVVGTINMDIRGM..ADIRY..PQSA.....SHP---GTIHCSAGGVGRNIAHNLAL.L... 182 WDVLGLGQAMVDFSGV..VDDEF..LKKLg18klLQAMDGCSYKAAAGGSLSNTLVALAR.L... 183 PIVLGCGQLCLDYLVT..VASFPi.PDQK.....IRG---TSFKVQGGGNTGNALTCVAR.L... 184 RIYTLTLAPSLDSATI..TPQIY..PEEN.....CAV---PHRCSNPGG-GINVARAIAH.L... 185 YDVAAIGNAIVDVIAQ..CDDAF..LEREg19lyDVM---SAAIEASGGSAANTVAGVAS.F... 186 -KIVSLGIHVLDVLGRh.VNRFPp.GGEL.....DII---NEIRLTVAGTAAGMSVDLAK.L... 187 -MILCCGEALIDMLPR..DTTLGe.----.....------KGFAPYAGGAIFNTAIALGR.L... 188 LDVICMGNLNYDITFI..LERFPe.FHEK.....VNA---KEVYTGLGGSAGNTATWLSL.L... 189 -TVLVVGDLILDRFVNgvIERIS..PEAP.....IPVLHGRGETSAMGGAG-NVVANIVS.L... 190 -KVVVVGGANMDLKAR..VRGEA..VPGT.....SNP---GVTSQSPGGVARNVAENLAR.L... 191 PRVLCLGEVLFDCLAD..QLGLK..LEQV.....------KSWTAYPGGAPANVACALVK.L... 192 -TVLVLGDVMLDRFIYgaVDRIS..PEAP.....VPVIAVEKETAMLGGAG-NVARNVAA.L... 193 -NIAVVGSISMDLVAV..SKKRPk.AGET.....VIG---EAFHTIPGGKGANQAVAAAR.L... 194 --ITVTLNPAIDQTIQ..LEHLQ..PGAV.....HRA---SSVRNDAGGKGINVAACLAD.W... 195 -DAVGLGALNMDQLHM..VERIAg.PDEE.....VFV---RSILESCGGSAANTIIGLAR.L... 196 KKVVTFGEIML-----..--RLA..PPGF.....LRFSQASSFDVIYGGGESNVAVSLAN.Y... 197 LDVICIGAAIVDIPLQpvSKNIF..DVDS.....YPL---ERIAMTTGGDAINEATIISR.L... 198 MRVFAIGNPILDLVAE..VPSSF..LDEFf17riYSTLDQFNPTSLPGGSALNSVRVVQK.Llrk 199 MEPVIIGALILDVHAK..PSTTP..ISGT.....TVP---GQVLFAPGGVARNVADCIFK.L... 200 MKFYVIGDVTVDHLYH..LDRLPa.PGKE.....VTP---KRSTMQPGGSGGTISVTLAR.L... 201 MEPVIIGALILDVHAK..PSTTP..ISGT.....TVP---GQVLFAPGGVARNVADCIFK.L... 202 MRVFAIGNPILDLVAE..VPSSF..LDEFf17riYSTLDQFNPTSLPGGSALNSVRVVQK.Llrk 203 MRVFAIGNPILDLVAE..VPSSF..LDEFf17riYSTLDQFNPTSLPGGSALNSVRVVQK.Llrk 204 -QLVVFGEALTDFIRE..AD---..----.....------GRWRSVAGGSCWNVARVCAR.L... 205 MRVFAIGNPILDLVAE..VPSSF..LDEFf17riYSTLDQFNPTSLPGGSALNSVRVVQK.Llrk 206 -MYLVCGEALFDFFSE..EDASG..QASK.....------VTYKAIAGGSPFNVAVGLRR.L... 207 -KIVSLGIHVLDVLGRh.VNRFPp.GGEL.....DII---NEIRLTVAGTAAGMSVDLAK.L... 208 -MIYAIGEILIDFIAK..EEGKL..----.....KDV---REFEKHPGGAPANVVVGLRR.L... 209 KQILCVGLVVLDVISL..VDKYPk.EDSE.....IRC---LSQRWQRGGNASNSCTVLSL.L... 210 LKILVVGDVILDTYLYgnVERIS..PEAP.....VPVLEVEGEEFRLGGAG-NVAKNLSS.L... 211 KQILCVGLVVLDVISL..VDKYPk.EDSE.....IRC---LSQRWQRGGNASNSCTILSL.L... 212 NGILAIGNLLVDRALL..ISDYPq.ESML.....ATI---SNMELHCGGGCTNVLFNLAK.Ldp. 213 AIVLGCGGIAVDFLAT..VDSYPq.ADDK.....IRS---TSLKVQGGGNAANALTCAAR.L... 214 -MYLVCGEALFDVFSL..ESAAR..SNE-.....------LGFTAIAGGSPFNVAVGLRR.L... 215 KKIAVIGDVMIDKYIFghVSRIS..PEYP.....VPVVDVNRESSRLGGAA-NVAVNIHA.L... 216 KQILCVGLVVLDVISL..VDKYPk.EDSE.....IRC---LSQRWQRGGNASNSCTVLSL.L... 217 MSALICGSLAYDTIMV..FPDQF..KNHIl11vsFLV---PRMRREFGGCAGNIAYNLHL.L... 218 AIVLGCGGIAVDFLAT..VDSYPq.ADDK.....IRS---TSLKVQGGGNAANALTCAAR.L... 219 ----------------..-----..----.....---------------------RILQR.L... 220 -GIIAAGNMLVDHVHQ..IEQWPq.RGWL.....AEI---VHSERSTGGAPLNVLLTLAK.Myt. 221 MRVCGVGDNVVDRYF-..-----..----.....------NQKLMFPGGNAVNFAVHAQR.S... 222 MRVHVVGNVCVDTTFQ..LGRFPr.PGET.....LNA---SSHVDGLGGKGANQAVAAAR.T... 223 -------------VAP..VDWSL..LDQIp25ahISV---APLKKMAGGSVTNTVRGLSV.Gf.. 224 KIWIVNYACAIDYYVD..LNKQ-..----.....------KNSVLIPGGKGINVAIVMKS.L... 225 KKIAAFGEVMM-----..--RLQ..VPGY.....ELLSQANTLKYSFSGTGVNVAAALSH.L... 226 MGITVIGSLNYDLDTF..TDRLPn.AGET.....FRA---NHFETHAGGKGLNQAAAIGK.Lknp 227 -RIVTLGEIML-----..--RLS..PQGY.....NRFVQAKQFNAFYGGSEANVAVSLAV.F... 228 MGITVIGSLNYDLDTF..TDRLPn.AGET.....FRA---NHFETHAGGKGLNQAAAIGK.Lknp 229 MIITFTPNPSIDSTLS..LGEELs.RGSV.....QRL---DSVTAVAGGKGINVAHAVLL.A... 230 ----------------..-----..----.....----------TCFGGKGANQCVAAAK.L... 231 -LIVSAGEALTDLVTA..GG---..----.....------NTWHAHPGGAGWNVARACAR.L... 232 ----------------..-----..----.....----------------------GLSR.L... 233 --------ALVDYIYL..IDRYPq.RGGH.....SII---LSTRKSPGGAGANVAHNLAS.L... 234 -MILCCGEALIDMLPR..ITTQGe.----.....------PAFAPYVGGAVFNTAIALGR.L... 235 --FAAVGDNCIDRYR-..-----..----.....--A---PLRQSYVGGNAINVAVQLAR.L... 236 RKVICFGNVLLDRLVQ..LEDPQl.LERFg19laAEASESSRCLTNPGGSALNTARILKQ.L... 237 -SVLCVGCTVIDFVTI..NGSYP..MEDT.....DRR--CLDGFWQRGGNASNVSTVLRV.L... 238 MKLIAVGDNVVDYYQ-..-----..----.....------DQETFYPGGNALNVAVLAKR.L... 239 MVLGLQLSALIDHVAR..VDWSL..LNRIp30cr---DDLSSIRTIAGGSVANTIRGLSAgF... 240 --HLSVGRINIDIIAK..INKIPd.IDEF.....ETT---DTLEILPGGAAVNYAVAINK.F... 241 -TIAVIGKVFVDIKGT..SFAPL..HKDA.....KNV---GDIAFSNGGTGRNVAQNLGV.L... 242 MRVVSVGTCNMDFIFR..VQEFVe.PDSE.....MYI---DDIHILPGGSALNFAVWISA.L... 243 --VVCLGET-MAQIVP..IDGLR..LHEA.....------SACAFGVAGAESNVAISLSR.L... 244 MKIAVVGGTFWDIFIF..GENPHs.----.....------STIRESPGGSGLNVAYGLFL.L... 245 -VWIVNYACAIDYYLD..KHKQ-..----.....------QRGVLTPGGKGINMAIVMAL.F... 246 ----------------..-----..----.....-------------------------S.L... 247 MEPVIIGALILDVHAK..PSTTP..ISGT.....TVP---GQVLFAPGGVARNVADCIFK.L... 60 70 80 90 100 | | | | | 1 ..G.....VPSVATGFVGGY.MGKILVEELRKISKLITT.....NFVYVE.GETRENIEIIDEKN 2 ..G.....GSSAFIGKVGDDeFGRMLADILRL--NNVDN.....SGMRFD.HNARTALAFVTLRG 3 ..G.....GSSAFIGKVGDDeFGRMLADILKQ--NNVDN.....SGMRFD.HDARTALAFITLTA 4 ..G.....GGAAFVGKLGDDeFGRMLAAILRD--NGVDD.....GGVVFD.AGARTALAFVTLRA 5 ..G.....IDVTVGGFLGKD.NQDGFQQLFSE--LGIAN.....RFQVVQ.GRTRINVKL-TEKD 6 ..G.....GRAAFVGKLGDDdFGHMLAGILRK--NGVDD.....QGINFD.EGARTALAFVTLRS 7 ..G.....AEVAMIGCLGDDaYGDQLYRALQA--EGIDC.....QGVERV.AGESSGVALIVVDD 8 ..G.....IDVTVGGFLGKD.NQDGFQQLFSE--LGIAN.....RFQVVQ.GRTRINVKL-TEKD 9 ..G.....GRSAFVGKLGDDeFGHMLAGILRK--NGVDD.....QGINFD.TGARTALAFVTLRA 10 ..G.....GRSAFVGKLGDDeFGHMLAGILRK--NGVDD.....QGINFD.TGARTALAFVTLRA 11 ..G.....VNVAVGGFLGKD.NSADFEQMFNQ--HGLED.....KFHRVD.GKTRINVKI-TETE 12 ..G.....ADIAFIACVGDDdIGERVRQQLTA--DKIDT.....QPIEAI.KGATTGVALIFVNS 13 ..G.....DEVITLGFLGPNa--QYIIDCLEE--EGIKS.....DFVKIK.NDTRTNIKISDISR 14 ..G.....AEVMMVTRVGDDvFADNTIRNLAS--FGVDT.....RHVVKV.SGKSSGVAPIFVEQ 15 ..G.....AKVAFISCIGSDsIGKTMKNAFAQ--EGIDT.....THINTV.SQEMTGMAFIQVAK 16 ..G.....INVSMIGMVGEDmFGDSNIKDLSS--NGVDT.....SCVGRT.KKTHTATATITVNK 17 ..G.....GSSAFIGKVGEDeFGYMLANILKD--NNVNN.....DGMRFD.PGARTALAFVTLTN 18 ..H.....VASKALGFVGGF.TGEYIKTFLRE--ENLET.....AFSEVK.GDTRINVKL---KT 19 ..G.....VPTQMVGRVGAQsFGAELMQNLQD--AGVQT.....DNIFVD.ETASSGVAMITVAH 20 ..G.....AEVFMISKIGKDeNGRELRDKLVE--DNIDV.....KYVFED.RIEPTGMALIMVND 21 ..C.....GRSAFFGRVGNDpFGRFMQQTLTD--EQVDC.....QHLYFD.PVHRTSTVVVDLDE 22 ..G.....IDVTVGGFLGKD.NQDGFQLLFSE--LGIAN.....RFQVVP.GRTRINVKL-TEKD 23 ..G.....LQTGFIGKVSDDqMGRFITGYLKD--NKINT.....DQIPIDcTGAVTGLAFTEIKS 24 ..G.....VNVALTGFLGQE.NQTGFQQLFSR--LGLTD.....HFHRIT.GATRINVKL-TESD 25 ..G.....LKAGFIGKIADDqHGRFIESYMRG--VGVDT.....SNLVVDqEGHKTGLAFTEIKS 26 ..K.....TDCVNLGFLGGF.TGTFIEQNLKK--LNILS.....DFVTVN.ENTRVNVKL---KT 27 ..N.....IESKCTGFIGGM.WEKDFREELDK--RGIKN.....EFITVS.GNTRTNTKIVDDLN 28 ..N.....SKVLMLTKVGDDiFADNTIRNLES--WGINT.....TYVEKV.PCTSSGVAPIFVNA 29 ..G.....GKSAFIGKFGDDeFGHMLVNILKK--NGVNS.....EGVCFD.TNARTALAFVTLKK 30 ..G.....KKVGFIGKVSDDrFGEFVVNYFKK--EGIDV.....SEISKAkNGESLGLTFTEILS 31 ..G.....LKAGFIGKIPDDqHGRFIESYMRK--TGVDT.....TQMIVDqDGHKAGLAFTEILS 32 ..G.....GECGFIGCLGDDdAGRFLRQVFQD--NGVDV.....TFLRLD.ADLTSAVLIVNLTA 33 ..N.....SKVLMLTKVGDDiFADNTIRNLES--WGINT.....TYVEKV.PCTSSGVAPIFVNA 34 ..G.....GNSAFIGCVGDDpFGEFMQTTLQR--EGVDI.....GKMFRI.DGQRTSTVLVSLDT 35 ..G.....GSATAIFPAGGA.TGEHLVSLLAD--ENVPV.....ATVEAK.DWTRQNLHVHVEAS 36 ..G.....GSATAIFPAGGA.TGEHLVSLLAD--ENVPV.....ATVEAK.DWTRQNLHVHVEAS 37 ..G.....ANARLVGLTGIDdAARALSKSLAD--VNVKC.....DFVSV-.PTHPTITKLRVLSR 38 ..G.....ANARLVGLTGIDdAARALSKSLAD--VNVKC.....DFVSV-.PTHPTITKLRVLSR 39 ..G.....VQSGIIGKIGLDdFGRIAVDNLMR--EGVDI.....SGLRVS.LRDRTGFSVVVRDK 40 ..G.....ANARLVGLTGIDdAARALSKTLAE--VNVKC.....DFVSV-.PTHPTITKLRVLSR 41 ..G.....ETVKATGCIGGE.SGDFIINHLPD---SILS.....RFYKIS.GDTRTCIAI--LHE 42 ..G.....ANARLVGLTGIDdAARALSKTLAE--VNVKC.....DFVSV-.PTHPTITKLRVLSR 43 ..G.....ANARLVGLTGIDdAARALSKTLAE--VNVKC.....DFVSV-.PTHPTITKLRVLSR 44 ..N.....VPSLATGFLGGF.TGGFIKDWLKN--EGIQT.....GFVIVK.DDTRINIKL---KH 45 ..G.....GTATAIFPAGGA.TGEHLVALLAD--ENVPV.....STVDAK.DWTRQNLHVHVESS 46 ..G.....GTATAIFPAGGA.TGEHLVALLAD--ENVPV.....STVDAK.DWTRQNLHVHVESS 47 ..G.....GSSAFVGKFGDDeFGHMLVDILKK--NGVNA.....EGCLFD.EHARTALAFVTLKS 48 ..G.....LKVGFIGKISDDqHGRFIEKYMRD--LNINT.....DGMVKDtAGRKVGLAFTEIKS 49 ..G.....GNVSMIGRVGNDeYGQKLYRDLKS--NGVGV.....EGIEFD.SETPTGTAYINVSE 50 ..G.....GESYFLGQVGNDsFGEFLVDMLKN--IGINT.....EMTKM-.-DGYTTLAFVAIDE 51 ..G.....LSARFIGAVGEDpLGEISLRELRA--EGVDV.....SFVKRV.RGVRSGVVVVLVHP 52 ..N.....VPSLATGFLGGF.TGSFIKDWLQN--EGVKT.....GFVTVK.DDTRINIKL---KH 53 ..G.....LKVGFIGKISDDqHGRFIEKYMRD--LAINT.....DGMVKDtEGRKVGLAFTEIKS 54 ..G.....LKSALLTRVGDEqMGRFIREQLQR--EGVET.....RGIVTD.PERLTALAILSVEN 55 ..Q.....VPVVATGLLGEA.NTELFEALFAR--KGMAD.....GFCRVP.GTNRTNIKISDQSD 56 ..G.....ATTGFIGRVGDDpLGRFMLNKLQQ--ENVCT.....QYMHLD.PKQRTSTVIVDLKE 57 ..D.....IASTATGFLGGF.TGRFIEESLSA--EGVKT.....DFVKGD.QDTRINVKI---KS 58 ..G.....SQVAALGVLGVG.NAGVFEALFRE--RGITD.....HCHRVA.GDTRTNLKLVEAQV 59 ..G.....LNSAVITRVGDEhMGRFIREQLVR--EGVDV.....RGVKTD.PERLTALVLLGIRD 60 ..G.....AKAAIVCKVGNDsFGNDYIENLKQ--NHIST.....EFTYQT.RDAATGTASIIVNN 61 ..K.....IDNIALGFLGGF.TGKFIEDNLKA--LGVKT.....EFIKVK.GDSRINVKI---KS 62 ..G.....LPVTASGLLGED.NAEVFDALFRT--KAITD.....AFVRVP.GQTRVGVKIVDHAA 63 ..G.....AMTSMVCKVGKDsFGNDYIENLKQ--NDIST.....EFTYQT.KDAATGTASIIVNN 64 ..G.....GNSGFIGAVGGDpFGRYMRHTLQQ--EQVDV.....SHMYLD.DQHRTSTVVVDLDD 65 ..G.....VPVRMVGAVGKDsFAGEALALLRE--AKVDL.....SGVAE-.TFASTGTALIMVGD 66 ..N.....IPNTATGFIGGF.TGKFITDTLAE--EEIET.....RFVQVA.EDTRINVKI---KA 67 ..N.....IPNTATGFIGGF.TGKFITDTLAE--EEIET.....RFVQVA.EDTRINVKI---KA 68 ..G.....DDVLASGLLGGK.LGEFLEAELDK--SAIKH.....SFYKIS.AETRNCIAI--LHG 69 ..G.....AKSKALGFLGGF.SGQYIKDFLNE--NQIDS.....DFTEIE.DLTRINVKL--KSQ 70 ..D.....IASTATGFLGGF.TGRFIEESLSA--EGVKT.....DFVKGD.QDTRINVKI---KS 71 ..G.....GSATAIFPAGGA.TGEHLVSLLAD--ENVPV.....ATVEAK.DWTRQNLHVHVEAS 72 ..S.....GKSAFFGRVGDDpFGRFMQSILDQ--EGVCT.....EFLIKD.PEQRTSTVVVDLDD 73 ..G.....ETVKATGCVGGE.SGDFIINHLPD---SILS.....RFYKIS.GDTRTCIAI--LHE 74 ..G.....IDVTVGGFLGKD.NQDGFQQLFSE--LGIAN.....RFQVVQ.GRTRINVKL-TEKD 75 ..G.....LRPSFYTRLGDDdAGRSLLQALRE--AGVRL.....DAIEVC.PGEISGSALVLVGD 76 ..G.....GAIRFVGAVGHDaFGELALKQMRE--FGLDT.....GSVRVI.DDVDTGMAIIQVEE 77 p.H.....RAATFFGCIGIDkFGEILKSKAAD--AHVDA.....HYYEQN.EQPTGTCAACITGG 78 ..G.....QDNTATGFIGGF.TGRFVEEGLIA--EGIKT.....NFVHVN.QDTRINVKI---KA 79 ..G.....SRVAMLGCVGDDpHGMALREGLLR--EGVDT.....AMVTAH.AGAPTGIACVTVAD 80 ..G.....REVSFLGKLGGDqFSEFLLEVMKK--EGIDT.....THIIFD.SSCKTTLAFVARDA 81 ..G.....KPSTALGFLGGF.TGDYIRFSLDS--RGIKN.....DFIKIK.YDTRLNIKM--IAN 82 ..G.....EDIVATGYIGGK.TGEFIEAKLKK--IGIKS.....DFVKVK.ASTRECLAF-ITDD 83 ..D.....VESTALGFAGGF.PGKFIIDTLNN--SAIQS.....NFIEVD.EDTRINVKL---KT 84 p.H.....KAATFFGCIGIDkFGEILKRKAAD--AHVDA.....HYYEQN.EQPTGTCAACITGG 85 p.H.....KAATFFGCIGIDkFGEILKRKAAD--AHVDA.....HYYEQN.EQPTGTCAACITGG 86 ..P.....NEVSMIGAVGKDaFGESILQNFKE--NAVLF.....ENVGTV.PQ-TTGIAQITLYD 87 ..Ge....KGCRFVTCIGNDdYSDLLIENYEK--LGI-T.....GYIRV-.-SLPTGRAFIEVDK 88 ..N.....VPVTFLSVVGNDdEGRRLLEETRQ--AGVNV.....EQVVIS.NTRRTGIYLAILNA 89 ..G.....LRSALITRVGDEhMGRFLLRELER--EGVDT.....RGIVTD.PERLTALVILGIRD 90 ..G.....ETVKATGCIGGE.SGDFIINHLPD---SILS.....RFYKIS.GYTRTCIAI--LHE 91 ..G.....AAAHFIFKVGKDqFSAFAMNHIIQ--SGITS.....YSAYQT.DKAPTGSALIYVSA 92 ..G.....DKVTATGFLGGK.IGEFIESELEQ--SPVSP.....AFYKIS.GNTRNCIAI--LHE 93 ..M.....YPTYFVGRLGEDaHGKLIAEALGDDGCGVHL.....DYVRSV.NNEPTGHAVVMLQS 94 ..M.....YPTYFVGRLGEDaHGKLIAEALGDDGCGVHL.....DYVRSV.NNEPTGHAVVMLQS 95 p.H.....KAATFFGCIGIDkFGEILKSKAAE--AHVDA.....HYYEQN.EQPTGTCAACITGD 96 ..G.....VENVALGFTGGF.TGRFIKDVLQT--EGVIT.....NFVQVD.GDSRINVKI---KG 97 ..G.....ADTTFLTRLGVDaFADMAKRTWQD--AGVKS.....AVIDTP.DSYTGAAYIFVEEG 98 ..G.....GCSTALFPAGGS.TGSLLMALLGD--AGVPF.....RVIPIA.ASTRESFTVNESRT 99 ..G.....GYTKIVGFIGMDnEGLILKKLMDH--IRIDS.....DLISI-.KNNKTITKIRILSE 100 ..G.....GAAHFVGMLGRDmFGDFLLESLQQ--AGVVT.....DGIVRT.DEAKTALAFVALDA 101 ..G.....AQVTVTGFLGRD.NQELFCQLFEQ--LGVQD.....AFIRIA.GATRINVKLV-EQS 102 ..G.....AKPAVLTAVGKDeLGKTLLSRAEE--MGVDT.....SYILLD.EKRPTGTVTVELQA 103 p.H.....KAATFFGCIGIDkFGEILKSKAAE--AHVDA.....HYYEQN.EQPTGTCAACITGD 104 ..D.....VESTALGFAGGF.PGKFIIDTLNN--SAIQS.....NFIEVD.EDTRINVKL---KT 105 ..Q.....QPTHIIGIFGGF.TGRYIVEELRQ--KKIKV.....TPAWVS.EPPRINIFI--NDG 106 ..G.....SQVAALGVLGVG.NAGVFEALFRE--RGIGN.....HCHRVA.GDTRTNLKLVEAQV 107 ..G.....DSVLATGLVGGK.LGEFLVEHIDN---QVKK.....DFFSIK.GETRNCIAI--LHG 108 ..G.....HETKALGFLGGF.TGAYVRNALEK--EEIGL.....SFIEVE.GDTRINVKI---KG 109 ..G.....YPTTALGFLGRD.NKEMFEHYLVN--QKVAA.....FFREVN.GKNRTNIKIKSLEI 110 p.H.....RAATFFGCIGIDkFGEILKSKAAN--AHVDA.....HYYEQN.EQPTGTCAACISGG 111 ..G.....EPVLASGFIGGE.LGQFIAKKLDH--ADIKH.....AFYNIK.GETRNCIAI--LHE 112 ..G.....GKSQLMSPVGMDfSSSGYEQLLKD--AHVDL.....SRLYSI.EALKLSKAFIFTDR 113 ..G.....HEVTVTGFAGGT.TGGVVREGLTGV-PGVTD.....ALVPVA.GATRRTIAVVDERT 114 ..G.....AKSTFVGKVGDDlLGRFLKETLTK--ANVNT.....EHMLFS.KEVRTGATFVTLAA 115 ..G.....EPVLASGFIGGE.LGQFIAKKLDH--ADIKH.....AFYNIK.GETRNCIAI--LHE 116 ..G.....DSVLATGLVGGK.LGEFLVEHIDN---QVKK.....DFFSIQ.GETRNCIAI--LHG 117 ..D.....ADVLASGLLGGF.FGDFIKNDLNI--NGIKH.....SFSDIS.GETRNCIAI--LHE 118 ..G.....GNSKIIGFIGMDyEGLTLKKLLNH--TRIYP.....DLISI-.KKNKTITKIRILSE 119 ..G.....LKVGFIGAVGNDdFGRLHLEFFRE--IGVDT.....SGIKVV.ND-ATGIAVTMVKG 120 ..G.....VPSVATGFVGGY.MGKILVEELRKISKLITT.....NFVYVE.GETRENIEIIDEKN 121 ..G.....FDSCLVSKVGDDpFGEFLVESLRR--ENVKT.....DGIVKD.EEKHTGIVFVQLTG 122 ..D.....IDAGLVGSVGDDeHGLLAQRELQA--AGVDL.....AGLRVV.DGLETSVKYLLVDS 123 ..G.....ANARLVGLTGIDdAARALSKTLAE--VNVKC.....DFVSV-.PTHPTITKLRVLSR 124 ..G.....GDSGFIGRVGDDpFGRFMRHTLAQ--EQVDV.....NYMRLD.AAQRTSTVVVDLDS 125 ..G.....IKNEALGIAGSD.NLDKLYAILKE--KHINH.....DFLVEA.-GTSTRECFVVLSD 126 ..G.....RRTVAVLPLGGA.PGALVADLLDA--QGIEV.....APVPIT.GPTRSNIALA-EAD 127 p.H.....RAATFFGCIGIDkFGEILKSKAAN--AHVDA.....HYYEQN.EQPTGTCAACISGG 128 ..G.....AQVFMVGKVGDDhYGTAILNNLKA--NGVRT.....DYMEPV.THTESGTAHI-VLA 129 ..G.....LRTSLVSAVGGDfEGSEYRELLES--SGIDI.....ESMILV.ADESTPTAFVMTDS 130 ..G.....VNTNFMSILGNDeHGKSIVEHSKK--IGYHM.....DDSMVI.EGGSTPTYLAILDE 131 ..G.....ARTALLARVGDDdYGRLLLDSQRA--AGVDT.....VGVLV-.GGAPTGVALITVDP 132 ..G.....IKNEALGIAGSD.NLDKLYAILKE--KHINH.....DFLVEA.-GTSTRECFVVLSD 133 ..G.....GRAAYFGKVADDqLGEIFTHDIRA--QGVHF.....QTKPLD.GHPPTARSMIFVTE 134 ..G.....LKTAMISRVGDEqMGRFLRETLER--EGCDT.....SQLQTD.PERLTALVLLGLKD 135 ..G.....HRLTVSGFLGED.NQPPFTAMFQR--RGFAD.....AFVRVP.GETRSNIKL-AERG 136 ..G.....HSAQYITKLGEDpFGEFIRRRLNE--ENVGT.....DYISST.NKKFTGFQLKSKVS 137 ..G.....GKSQLISPVGTDfSSSGYEKLLKE--AYVDL.....SRLYTI.EDRKISKAFIFTDR 138 ..G.....VSAAFVGRLGADqAGQELKNVLQQ--CQVNT.....DGLQID.PHRPTRLVYVTRTG 139 ..N.....VPVQLMGLIGQDeTGSALSHLLEK--QKIDC.....NFVAL-.ETHPTITKLRILSR 140 ..G.....NKAWLLSAVGSDfYGQSLLTQTNQ--SGVYV.....DKCLIV.PGENTSSYLSLLDN 141 ..G.....GSASFLGKVGNDpFGHFLKETLDE--VKVDT.....SMLIMD.NNSSTTLAFVSLQA 142 ..G.....AKVTMIGAVGTDqMAGEALTHLRQ--SGADM.....SAIATV.-DGPTGLAIITVSD 143 ..G.....AQVDFIGRVGDDdTGNSLLAELES--LGVNT.....RYTRRY.TQAMSSQSAIMVDA 144 ..G.....ARTAVLTAVGKDeLGKILLSRAEE--MGVDT.....SYILID.EKRPTGTVTVELKY 145 ..G.....ADVAFVGAVGKDpYAAPALEFLRS--SGVDL.....TAVSEV.DD-TTGLAVITVAK 146 ..G.....AQVDFIGRVGDDdTGNSLLAELES--WGVNT.....RYTKRY.NQAKSSQSAIMVDT 147 ..G.....LHCVAIGHVGDEiYGEFLLDVLHE--EGIGTva7gtNEKDTS.SFCETLICWVLVDP 148 ..G.....GDAAFSGKVGKDpFGYFLKRTLDA--VHVDT.....SMLVMD.EKAPTTLAFVSLKQ 149 ..G.....LDAYFVTKLPNNpLGDAAAGHLRK--FGVKT.....DYIAR-.GGNRIGIYFLEIGA 150 ..G.....AQVDFIGRVGDDdTGNSLLAELES--WGVNT.....RYTKRY.NQAKSSQSAIMVDT 151 ..G.....AQVDFIGRVGDDdTGNSLLAELES--WGVNT.....RYTKRY.KQAKSSQSAIMVDA 152 ..G.....AQVFMVGKVGDDhYGTAILNNLKA--NGVRT.....DYMEPV.THTESGTAHI-VLA 153 ..G.....VKSSLISKVGNDpFGEYLIEELSK--ENVDT.....RGIVKD.EKKHTGIVFVQLKG 154 ..G.....GHATFMGQVGNDpFGEFLEQTLQH--AHVDT.....SMLIK-.-DKQTTLAFVSIDQ 155 ..G.....VNSELLSCVGYDfKNSGYERYLKN--LDINI.....SKLYYS.EEEETPKAWIFTDK 156 ..G.....VPSAFFTGLSDDmMGDILRETLRA--SKVDF.....SYCAT-.LSRPTTIAFVKLVD 157 ..G.....VPTGFFTGLSDDmFGDILRATLKA--ANVDF.....APCAT-.LPLHTTLAFVKLVD 158 ..G.....VPSAFFTGLSDDmMGDILRETLRA--SKVDF.....SYCAT-.LSRPTTIAFVKLVD 159 ..G.....NKAWLLSAVGSDfYGQSLLTQTNQ--SGVYV.....DKCLIV.PGENTSSYLSLLDN 160 ..G.....HGVAVTGLLGAE.NAALFARHFAA--TGLVD.....ACQRLP.GATRTNVKIVDPLQ 161 ..G.....ANVRMIGRVGDDpFGHVLTENLAK--EGIIT.....DSVKPV.TDCTSGVATILLSD 162 ..N.....VPVQLMGLIGQDeTGSALSLLLEK--QKIDC.....NFVAL-.ETHPTITKLRILSR 163 ..Q.....IPAHILGIFGGF.TGHYIVESLRT--RKMPV.....TPAWVE.EPTRINIFI--HDG 164 ..G.....GAPIPMGTVGQD.FGPY-REHFET--LGIDL.....SRVKII.DDLFTPQAFITTDH 165 ..Q.....IPAHILGIFGGF.TGHYIVESLRT--RKMPV.....TPAWVE.EPTRINIFI--HDG 166 ..G.....SHVKIIVAVGDDkHGTDAIEFWKS--ENIDV.....SKVKVK.SGINTGTAYIFVDK 167 ..G.....IPSFLVSKVGDDpFGRFLIRRLKE--EGVNT.....EGVLID.NEKHTGVVFVQLKG 168 ..G.....LRVGFIGAVGNDdFGRLHLEFFEK--IGVDT.....RGIKVV.D-EPTGVAVMMVIG 169 ..G.....LPLQAVGLIGQDsDGDYIMAMLEQ--YHVNR.....QHVQRT.TFAPTSMSQVMTDP 170 ..G.....HSVGWVSKVGNDeLGKYVISAIRG--EGVDT.....SQVVLD.DGAPTGLYLKEKLR 171 ..G.....RDVHLLSVIGDDfYGEMLLEETRR--AGVNV.....SGCVRL.HGQSTSTYLAIANR 172 ..G.....GRSAYFGKVATDhLGRVFAHDIRA--QGVAF.....DTRPLE.KGSPTARSMIFVTP 173 ..G.....HRTALMSRIGKDaAGQFILDHCRK--ENIDI.....QSLKQD.VSIDTSINVGLVTE 174 ..G.....LRSALLTRVGDEqMGRFIREQLRR--EGVNT.....DGLKTD.KERLTALVLLSVES 175 ..G.....HRTALMSRIGKDaAGQFILDHCRK--ENIDI.....QSLKQD.VSIDTSINVGLVTE 176 ..G.....LRSSMLARVGDEhMGRFLREELHQ--VGCDT.....SHLTTD.KKRLTALVLLSIKD 177 ..G.....RDVHLLSVIGDDfYGEMLLEETRR--AGVNV.....SGCVRL.HGQSTSTYLAIANR 178 ..N.....VPVKLLGLTGRDeTGLALESLLAK--SRIEC.....DFVQL-.HTHPTITKLRILSR 179 ..Gsq8rpLNVAMAGSIGGDpLGSFYGTKLRR--ANVNF.....LSAPI-.KDGTTGTVIVLTTP 180 ..Gsq8rpLNVAMAGSIGGDpLGSFYGTKLRR--ANVNF.....LSAPI-.KDGTTGTVIVLTTP 181 ..G.....RDVHLLSVIGDDfYGEMLLEETRR--AGVNV.....SGCVRL.HGQSTSTYLAIANR 182 ..Gsq8rpLNVAMAGSIGGDpLGSFYGTKLRR--ANVNF.....LSAPI-.KDGTTGTVIVLTTP 183 ..G.....LPCRILAKVADDsHGRYMVEELES--SGVDT.....SFCMSA.KDGASHFNYVIVDN 184 ..G.....GSATAIFPAGGA.TGEHLVSLLAD--ENVPV.....ATVEAK.DWTRQNLHVHVEAS 185 ..G.....GKAAFLGKVADDqLGRVFRHDMNA--IGCVF.....TTPPLA.EGPATAQSLINVTP 186 ..G.....GDVYAMGAVGLDeSGNFIIDTLRR--YGVNT.....DHIVRK.SEVQTSCSMLPIRP 187 ..G.....IPTAFFTGIADDmMGEILLETLKA--SNVDY.....SPCAI-.TPRPSTIAFVKLVN 188 ..G.....LKVGFIGSVGNDdFGRLHLEFFKK--IGVDT.....RGIKVV.D-EPTGVAVMMVIG 189 ..G.....ARAIPVSVIGTDtAGDSLVRMLAE--LGAET.....AGLSQQ.RGRMTSSKSRFSAL 190 ..G.....VSAALVSAVGPDsLGDVLLRETEA--AGVDV.....SGVLRV.SGAATGSYTAVLGA 191 ..G.....TPAGFIGAVGEDePGNVLVKLLQE--VGVDT.....TGVQRH.STAPTRQVYVVRDL 192 ..G.....AKAVLIGLVGRDdAGAALRGMIDA--EAGLE.....AELVVD.PARRTTEKVRYISG 193 ..G.....ANVAMVGAVGDDnYGTVVKRNLEN--ERVFI.....DYVVPV.TDAATGIAHIVLAE 194 ..G.....SEVAALGALGVG.NAGVFEALFRE--RGIAD.....HCQRVA.GETRTNLKLVDARS 195 ..G.....LRTAFIGKVAGDrEGSILRENLKG--GGV-A.....DYVAVS.DEGRSGRVMGFVDP 196 ..G.....VPVDFVTRLPKNdIGECALMEMRK--RGVGT.....DHIVW-.GGDRLGIYFLETGA 197 ..G.....HCTALMSRIGKDaAGQFILDHCRK--ENIDI.....QSLKQD.VNIDTSINVGLVTE 198 ..P.....GSAGYMGAIGDDpRGQVLKELCDK--EGLAT.....RFMVA-.PGQSTGTCAVLINE 199 ..G.....ITPFMIGTLGLDgPANVLLKE-----WKLSM.....KGILRR.EDISTPIVSLVYDT 200 ..G.....HTVTLAARVGDDpFAEFALAEIKA--SGVSL.....SAIQKD.PEHLTSTITVMQTS 201 ..G.....ITPFMIGTLGLDgPANVLLKE-----WKLSM.....KGILRR.EDISTPIVSLVYDT 202 ..P.....GSAGYMGAIGDDpRGQVLKELCDK--EGLAT.....RFMVA-.PGQSTGVCAVLINE 203 ..P.....GSAGYMGAIGDDpRGQVLKELCDK--EGLAT.....RFMVA-.PGQSTGVCAVLINE 204 ..G.....APTGFAGTVSRDvFGDELTALSRQ--AGLDM.....RFMRQV.ARPPLLA---MVPA 205 ..P.....GSAGYMGAIGDDpRGQVLKELCDK--EGLAT.....RFMVA-.PGQSTGTCAVLINE 206 ..G.....IEAGLFGGLSSDfLGRRLLQVLKD--EGVSE.....RFLVE-.FAAPTTLSMVAVGA 207 ..G.....GDVYAMGAVGLDeSGNFIIDTLRR--YGGNT.....DHIVRK.SEVQTSCSMLPIRP 208 ..G.....AKSALISKVGDDpFGEFLIEELKK--ERVET.....KYIIKD.TNKHTGIVFVQLIG 209 ..G.....APCAFMGSMAPGhVADFVLDDLRR--YSVDL.....RYTVFQ.TTGSVPIATVIINE 210 ..G.....VETYLCGVVGKDeAGKRLRELIEG--NSI--.....RSFLIE.DERPTTKKTRVVSR 211 ..G.....APCAFMGSMAPGhVADFVLDDLRR--YSVDL.....RYTVFQ.TTGSVPIATVIINE 212 ..H.....LPLFLAGAIGQDgEGQLILQQAKQ--HHINV.....DNVVQL.ALPTSFTDVMINSQ 213 ..G.....LNSRLISKVANDsQGKGMLEELEA--DGVDT.....SFIVVS.KEGNSPFTYILVDN 214 ..G.....VEAALFGGLSSDyLGARLRRVLEE--EGVDC.....GFLVP-.SDAPTTLAMVGLDA 215 ..G.....AEALLIGVTGDDtERRNLEALMTE--HGLNP.....AMLAAD.STRPTTCKTRILSQ 216 ..G.....APCAFMGSMAPGhVADFLVADFRR--RGVDV.....SQVAWQ.SKGDTPSSCCIINN 217 ..G.....GAPIPMGTVGQD.FGPY-REHFET--LGIDL.....SRVKII.DDLFTPQAFITTDH 218 ..G.....LNSRLISKVANDsQGKGMLEELEA--DGVDT.....SFIVVS.KEGNSPFTYILVDN 219 ..D.....IASTATGFLGGF.TGRFIEESLSA--EGVKT.....DFVKGD.QDTRINVKI---KS 220 ..G.....LPLQAVGLIGDDhDGDYIMAMLDQ--YQVNR.....QHVRRT.TLAPTSMSQVMTDP 221 ..G.....MDAAYIGVIGTDaDGDLIRSSLQA--EGVEL.....KHLRV-.KEGPNAFATVHMDE 222 ..G.....ADVCFRAAIGDDtAGLWIRERLSR---DLDA.....SHLTV-.LALPSDRSTIIVDV 223 ..G.....VATGIIGAYGDDeQGQLFVSNMGF--SGVSI.....SRLRK-.KKGSTAQCVCLVDD 224 ..G.....FDPTVITFLGQP.TKNLFLELVKP--YDLNI.....VSFISE.TKTRINLKL--LKD 225 ..G.....HEGFLISTLPENsVGDAALSYIQK--LGVQT.....SLVSR-.GGKYVGMYFLENGF 226 ssR.....YSVRMIGNVGNDtFGKQLKDTLSD--CGVDI.....THVGTY.EGINTGTATILIEE 227 ..G.....KDVSYTTKLPDNaIAQCAINELRK--YGVNT.....KDIVR-.GGDRIGLYFCENGE 228 ssR.....YSVRMIGNVGNDtFGKQLKDTLSD--CGVDI.....THVGTY.EGINTGTATILIEE 229 ..G.....FETLAVFPAGK-.-LDPFVPLVRD--IGLPV.....ETVVIN.KNVRTNTTV-TEPD 230 ..G.....ASTVLVAKLGKDeSGDDYLNHLQQ--HEVDV.....THVQQV.ENNPTGMSEIAVSE 231 ..G.....VPSAFAGAVGQDnFGDDLHRESLE--AGLDP.....RFLQRV.P-APTLMAV--VYS 232 ..G.....IETAYIGKVGSDeEGRILLADFER--EGVST.....DFVIR-.AEGRSGTAMIFVDE 233 ..G.....VESTLFTTLGRDeDGIYFVENTLA---KVK-.....---AEI.TDEKTGKVHVFVDG 234 ..G.....APAGFFSGLSSDlFGGQFRDALGA--SKVSS.....TYAHT-.SPRPTTLAFVRLTN 235 ..G.....HGSFYFGAVGRDsDGAQVRRLLLA--NGVNV.....DHLLA-.RDTNTAYTDIDVTP 236 ..G.....TDALFFGAVGADkHAEELRQIIRD--RGIEA.....RLQTV-.EDAHTGQCVCLMYQ 237 ..G.....CKVDFFGMLSRSdGFRVLLDDLSK--REIGT.....NDCPFT.DRDPPFSSVILAQD 238 ..G.....HESSYIGIVGNDeAAAHLLNVLKL--EQVNA.....DYIRQ-.AHGENGMAIVTLDE 239 ..G.....ISTGIIGACGDDsQGVLFVSNMSF--SGVDL.....TRLRT-.KKGHTAQCL--VDA 240 ..G.....HSIKILSKIGKDsLVSYVLERIAE--MGVGL.....DYVEE-.TNLPQSMALIFLRD 241 ..G.....NDVRFVSTVTNDqIGIGVLEELRS--LNVNV.....EHVDLL.EDNGMGMWLAVMDN 242 ..G.....FSSDIVAATGGDmYGEIIRSRLES--EGVST.....GCLSVV.EK-PTGMAFISVDG 243 ..G.....TAAFWAGFVGDDpMGLRVLGELRR--HGVVT.....KLARTM.PGRRTGVYFKDPAP 244 ..G.....HTVDFYSNIGDDwRGKQIVELLEK--ASFDT.....SHMSTI.QGGKTGIFI---AH 245 ..G.....IKPTVLTFLGQP.TKDLFLQLLKP--YQLDL.....VSFPAT.TQTRINVKL--LDG 246 ..G.....FDPTVITFLGQP.TKNLFLELVKP--YDLNI.....VSFISE.TKTRINLKL--LKD 247 ..G.....ITPFMIGTLGLDgPG-----ILRR-------.....------.EDISTPIVSLVYDT 110 120 130 140 1 | | | | 1 ...KTITAINFPG....PDVTDMDVN..HFLR.....RY..KM.TLSKVDCVVISGS...IPPGV 2 ...DGEREFLFFR....HPSADMLLL..E-SE.....LD..KN.LIQKAKIFHYGSIs..LIEEP 3 ...EGEREFVFFR....NPSADMLLR..E-SE.....LD..VD.LIKKATIFHYGSIs..LIDEP 4 ...DGEREFMFYR....NPSADMLLT..H-AE.....LN..VE.LIKRAAVFHYGSIs..LIAEP 5 ...GEVTDFNFSG....FDVTPADWE..RFVN.....DS..LS.WLGQFDMVCVSGS...LPAGV 6 ...DGEREFMFYR....NPSADMLLR..P-DE.....LN..LE.LIRSAKVFHYGSIs..LITEP 7 ...SSQNAIVIVA....GGNGHLSPA..V-LA.....RH..EH.LLEQAQVVVCQ--...--LES 8 ...GEVTDFNFSG....FEVTPADWE..RFVT.....DS..LS.WLGQFDMVCVSGS...LPSGV 9 ...DGDREFMFYR....NPSADMLLR..P-DE.....LN..LD.LIRSAKVFHYGSIs..LIVEP 10 ...DGDREFMFYH....NPSADMLLR..P-DE.....LN..LD.LIRSAKVFHYGSIs..LIVEP 11 ...ADVTDLNFLG....YQISPQVWQ..QFVT.....DS..LA.YCLNYDIVAVCGS...LPRGV 12 ...DGENVIGINA....GANSAVTPE..Y-LR.....RY..QQ.QVIDADALLMQ--...--LES 13 ...GEVTDLNEYG....PEVSEEEIE..LLKE.....SI..FR.YAEKSKVLVLSGS...LPLGV 14 ...SGENSILIVK....GANADLLPV..E-VD.....KA..AA.DLKECGLILMQ--...--MEV 15 ...SSENSIVLAS....GANSHLSEM..V-VR.....QS..EA.QIAQSDCLLMQ--...--LET 16 ...EGENNIVVTL....GANLEMSPE..I-AD.....AN..SS.KIAGSKMVICQ--...--GEI 17 ...EGEREFMFYR....NPSADMLLE..E-SE.....LD..FD.LIKKAKIFHYGSIs..LITEP 18 ...GDETEINGQG....PTISDEDFK..AFLE.....QF..-Q.SLQEGDIVVLAGS...IPSSL 19 ...NGENQIVVIP....GANGRVNQV..D-VE.....RL..SR.ILPTATALLLQ--...--LEI 20 ...NGNNSIIVNA....GSNMTLTKE..E-IH.....SA..EN.LIKESDIIISQ--...--FET 21 ...HGERSFTFMV....KPSADQFLQ..L---.....SD..IP.SFQNGEWLHVCSIa..LANQP 22 ...GEVTDFNFSG....FEVTKPDWD..RFVT.....DS..LS.WLGQFDMVAVSGS...LPAGV 23 ...PEDCSILMYR....DNVADLNLD..P-TE.....VS..ED.YIKQSKALLISGTa..LAKSP 24 ...GVVTDLNFQG....YHVSKTDWQ..TFVD.....FS..LQ.QCQTFDVIAVCGS...LPRGI 25 ...PEECSILMYR....QDVADLYLS..P-EE.....VN..EA.YIRRSKLLLVSGTa..LSKSP 26 ...ETETEINCQG....PKISENEKE..EFLD.....KI..-R.KIKSDDFVILSGS...VPSNL 27 ...KVYTDINEAG....PSISSKELE..MFMN.....KF..KD.MCNKDDIVVLSGG...VAPGI 28 ...NSSNSILIIK....GANKFLSPE..D-ID.....RA..AE.DLKKCKLIVLQ--...--LEV 29 ...DGEREFMFYR....NPSADMLLK..E-SE.....LN..KD.LIKKAKIFHYGSIs..LISEP 30 ...PTESSILMYR....NGIADLQLD..V-DD.....ID..ED.YIKNTKAIVISGTa..LAMSP 31 ...PEECSILMYR....DDVADLYLE..P-SE.....VS..ED.YIANAKMLLVSGTa..LAKSP 32 ...DGERSFTYLV....HPGADTYVS..P---.....QD..LP.PFRQYEWFYFSSIg..LTDRP 33 ...NSSNSILIIK....GANKFLSPE..D-ID.....RA..AE.DLKKCQLIVLQ--...--LEV 34 ...EGERHFTFMV....RPSADLFLR..T---.....DC..LP.SFAQGEGLHLCSIa..LSAEP 35 ...GEQYRFVMPG....AALNEDEFR..QLEE.....QV..LE.-IESGAILVISGS...LPPGV 36 ...GEQYRFVMPG....AALNEDEFR..QLEE.....QV..LE.-IESGAILVISGS...LPPGV 37 ...NQQLIRLDFE....EGFEGVDPQ..PLHE.....RI..NQ.ALSSIGALVLSDY...--AKG 38 ...NQQLIRLDFE....EGFEGVDPQ..PLHE.....RI..NQ.ALSSIGALVLSDY...--AKG 39 ...EGSITIYSFK....GAAEKLEPG..E---.....ID..AD.AIGRSKHVHVA--...---SL 40 ...NQQLIRLDFE....EGFEGVDPQ..PLHE.....RI..NQ.ALGSIGALVLSDY...--AKG 41 ...GNQTEILEKG....PLLSVEEID..GFTH.....HF..KY.LLNDVDVVTLSGS...LPAGM 42 ...NQQLIRLDFE....EGFEGVDPQ..PLHE.....RI..NQ.ALGSIGALVLSDY...--AKG 43 ...NQQLIRLDFE....EGFEGVDPQ..PLHE.....RI..NQ.ALGSIGALVLSDY...--AKG 44 ...GEETEINGLG....PAISEKEIK..EFLE.....VM..-D.KVTAGDIVILSGS...VPPSL 45 ...GEQYRFVMPG....ATLDDDEFR..QLEE.....QV..LE.-IESGAILVISGS...LPPGV 46 ...GEQYRFVMPG....ATLDDDEFR..QLEE.....QV..LE.-IESGAILVISGS...LPPGV 47 ...NGEREFMFYR....NPSADMLLT..E-AE.....LN..LD.LIRRAKIFHYGSIs..LITEP 48 ...PEECSILMYR....ENVADLYLT..P-EE.....IS..ED.YIKETRVLLVSGTa..LAQSP 49 ...KGENNIVVYQ....GANKRLNMT..Q-IK.....RY..EH.FFDEAEICLLQ--...--LEI 50 ...KGERDFEFHR....GSDGEYSFN..N---.....ID..LS.KIEKDDIIHFGSAtg.FLKGE 51 ...DGVKRMVSYR....GANLGLTPA..D---.....LT..VD.KFAGVKHIHLA--...---TG 52 ...GEETEINGLG....PAISEKEIN..EFLK.....VM..-D.KVTANDIVILSGS...VPPSL 53 ...PDECSILMYR....ENVADLYLT..P-EE.....IS..ED.YIKEARVLLISGTa..LAQSP 54 ...DKSFPLLFYR....DNCADNALC..E-DD.....IS..ED.FIRSARAVLVTGTh..FAKPN 55 ...GQTTDINLPG....ITAAPADLD..AVCE.....RV..-D.AVADVAGIALCGS...LAGGL 56 ...-GERSFTFMV....NPSADQFLE..L---.....SD..LP.HFNPNDWLHCCSIa..LINEP 57 ...QEETEINGQG....PVISREQLE..D-LK.....TK..LS.QLTAEDTVVFAGS...APANL 58 ...NETTDINLPG....LQLGQAHLQ..GVAD.....HL..AP.LLRAGLPVVLSGS...LPAGL 59 ...QNQFPLIFYR....ENCADMALS..E-DD.....ID..PA.FIADAGCICATGTh..LSHPN 60 ...EGQNIIVIVA....GANLFLNSE..D-LK.....KA..AS.VISRAKVMICQ--...--LEI 61 ...NEETEINGAG....PMITSEELD..SLFN.....RL..-D.QLVEGDILVLAGS...IPSTL 62 ...QQTTDINLPG....LRATPEHLR..ELHA.....QL..DA.LCESHDAFVLAGS...LPPGI 63 ...EGQNIIVIVA....GANLLLNTE..D-LR.....AA..AN.VISRAKVMVCQ--...--LEI 64 ...QGERTFTFMV....RPSADLFLV..E---.....ED..LP.QFAAGQWLHVCSIa..LSAEP 65 ...DGENIIAVVS....GANASVVTG..D---.....LS..KA.FLKKGDVVLLQ--...--HEI 66 ...DQETEINGTG....PTVEPVQLE..E-LK.....AI..LS.SLTAEDTVVFAGS...SAKNL 67 ...DQETEINGTG....PTVESVQLE..E-LK.....AI..LS.SLTAEDTVVFAGS...SAKNL 68 ...GYQTEILEQG....PYVSAKESK..GFLE.....FF..EK.LLPKLEVVAISGS...LPKGV 69 ...ENETSLDAAG....PKLQESEIN..HFLE.....KF..-D.HLKEDDIVVFAGT...IPKSL 70 ...QEETELNGQG....PIISQEQLE..D-LK.....TK..LS.QLTAEDTVVFAGS...APANL 71 ...GEQYRFVMPG....AALNEDEFR..QLEE.....QV..LE.-IESGAILVISGS...LPPGV 72 ...QGERSFTFMV....KPSADQFMS..V---.....ED..MG.NFKQGDWLHVCSIs..LANEP 73 ...GNQTEILEKG....PMLSVDEID..GFTH.....HF..KY.LLNDVDVVTLSGS...LPAGM 74 ...GEVTDFNFSG....FEVTPADWE..RFVT.....DS..LS.WLGQFDMVCVSGS...LPSGV 75 ...DGSNMIVIDP....GANANVTPS..M-VE.....KA..AE.FIERDAIVVAE--...--MGM 76 ...TGQNTIAVCA....GANARWSSA..D-ID.....AY..GA.DIAKARITLLQ--...--REV 77 ...NRSLVANLAA....ANCYKKEKH..LDLE.....NN..WM.LVEKARVYYIAGFf..--LTV 78 ...DQETEINGTG....PVITKEQVL..A-LE.....NI..LQ.QLSQDDTVVFAGS...APSNL 79 ...NGQNTIVIVA....GANRQLTPA..M-ID.....AQ..RA.AFERAKVIVCQ--...--LES 80 ...QGNPDFVFFR....EKPADTNLR..P-EE.....VN..ID.-PAQFSFLHIGSYs..LAVEP 81 ...GRETEINANS....PDISENEFE..L-LK.....NK..LK.NLANNSTLVMSGS...VPAAL 82 ...LVQTEILEPG....PEISEEEQD..QFMK.....VY..EK.LLVKCNIIVASGS...APRNV 83 ...GQETEINAPG....PHITSTQFE..QLLQ.....QI..-K.NTTSEDIVIVAGS...VPSSI 84 ...NRSLVANLAA....ANCYKKEKH..LDLE.....RN..WV.LVEKARVYYIAGFf..--LTV 85 ...NRSLVANLAA....ANCYKKEKH..LDLE.....RN..WV.LVEKARVYYIAGFf..--LTV 86 ...DDNRIIIIPG....ANNEV--LP..SYLA.....DL..WE.KIKESQLVILQ--...--NEI 87 ...TGQNRIIIFP....GANAELKKE..L---.....ID..WN.TLSESDILLLQ--...--NEI 88 ...IGDMDIALSG....MDILEELNI..QYLE.....SK..TE.VIKNSEIVVFD--...--ANI 89 ...QQHFPLIFYR....ENCADMALC..E-DD.....ID..PD.FIAEARCVLATGTh..LSHPR 90 ...GNQTEILEKG....PMLSVDEID..GFTH.....HF..KY.LLNDVDVVTLSGS...LPAGM 91 v..DGDNIIAIYP....GANMMLTTQ..E-IN.....EQ..HR.YIAESDVMLMQ--...--LET 92 ...GNQTEILEQG....PTISHEEAE..GFLD.....HY..SN.LIKQSEVVTISGS...LPSGL 93 ...DGQNSIIIVG....GANMKAWPE..IMSD.....DD..LE.IVRNAGIVLLQ--...--REI 94 ...DGQNSIIIVG....GANMKAWPE..IMSD.....DD..LE.IVRNAGIVLLQ--...--REI 95 ...NRSLVANLAA....ANCYKKEKH..LDLE.....NN..WV.LVEKARVYYIAGFf..--LTV 96 ...QEETELNGQG....PSVTNEQFE..QLMK.....QI..-E.SMQKGDYVVLAGS...VPASI 97 ...SGNNAIIVSP....GAAMLISPT..D-IE.....AN..AA.LIRGAGVFVTQ--...--LEQ 98 ...AKQYRFVLPG....PSLTVAEQE..QCLD.....EL..RG.AAASAAFVVASGS...LPPGV 99 ...KKQLIRVDFQ....EKYISNKNN..LLHQ.....KI..ID.SISSFKILVLSDY...--AKG 100 ...AGERSFSFYR....PPAADLLFR..A-EH.....FA..AD.GFAQAAVLHVCSNs..MTEPA 101 ...GAVSDINFPG....IQVTEADIE..AFEA.....TL..QR.LAQDHDYFVLAGS...LPQGI 102 ...EGIPIFTINE....GVAWDAITP..DERE.....FE..AL.AAEEWDVFCFGTLa..QRSEE 103 ...NRSLVANLAA....ANCYKKEKH..LDLE.....NN..WV.LVEKARVYYIAGFf..--LTV 104 ...GQETEINAPG....PHITSTQFE..QLLQ.....QI..-K.NTTSEDIVIVAGS...VPSSI 105 ...AEEYKLVNPG....AKIDDECKQ..QVIH.....HL..-Q.CVASGDYLAISGS...LPPGI 106 ...NETTDINLPG....LQLGQAHLQ..GVAD.....HL..AP.LLRAGLPVVLSGS...LPAGL 107 ...DNQTEVLEKG....PEVLEQEGQ..EFLE.....HF..KK.LLESVEVVAISGS...LPAGL 108 ...KQETELNGTA....PLIKKEHVQ..ALLE.....QL..T-.ELEKGDVLVLAGS...VPQAM 109 ...KQETELNGLA....FSPSDDDVM..ALLT.....IL..KT.ELTKNDCLIISGS...LPRDC 110 ...NRSLVANLRA....ANCYKKEKH..LDLE.....NN..WM.LVEKARVYYIAGFf..--LTV 111 ...GQQTEILEQG....PEIDNQEAA..GFIK.....HF..EQ.LLEKVEAVAISGS...LPKGL 112 ...EDNQTTYFYW....GASSKFKEL..EPEP.....VD..FA.HLATADCIYNA--...----- 113 ...GDTTQLNEPG....PAVAPAEWN..AFQE.....AY..ED.LLAGVAAVALCGS...LPPGV 114 ...NGERSFDFYI....NPSADRFLE..K-GE.....IA..PT.LFEEHGVLHFGSIs..LISEP 115 ...GQQTEILEQG....PEIDNQEAA..GFIK.....HF..EQ.LLEKVEAVAISGS...LPKGL 116 ...DNQTEVLEKG....PEVLEQEGQ..DFLE.....HF..KK.LLESVEVVAISGS...LPAGL 117 ...GNQTEILESG....PNISEKEAN..NFLR.....HF..EL.LVDKANIISISGS...LPLGI 118 ...KKQLIRLDFQ....EKYISKKFN..LLYE.....KI..IS.SLTYYKVLVLSDY...--AKG 119 ...EDKRIVKYPG....ANRWKE---..----.....VN..TE.YLKRARHLHLS--...---SN 120 ...KTITAINFPG....PDVTDMDVN..HFLR.....RY..KM.TLSKVDCVVISGS...IPPGV 121 ...VSPSFILYDG....VAYFNLRRE..D---.....IN..WE.LINSSRIVHFGSVi..LARSP 122 ...RGEVMVLGND....GANEAVAPG..DLDP.....A-..-V.VGADCEHVHLT--...---SQ 123 ...NQQLIRLDFE....EGFEGVDPQ..PLHE.....RI..NQ.ALGSIGALVLSDY...--AKG 124 ...HGERTFTFMV....RPSADLFLQ..P---.....ED..LP.PFAAGQWLHVCSIa..LSAEP 125 dt.NGSTMIPEAG....FTVSQTNKD..NLLK.....QI..AK.KVKKEDMVVIAGS...PPPHY 126 ...GVLTKINAPG....PELTPDERE..LLLE.....TV..RR.QSPGADWIACCGS...LPRGL 127 ...NRSLVANLRA....ANCYKKEKH..LDLE.....NN..WM.LVEKARVYYIAGFf..--LTV 128 ...EGDNSIVVVK....GANDDITPA..YALN.....AL..-E.QIEKVDMVLIQ--...--QEI 129 ...DHNQISYFYW....GAARYFKDA..E---.....TP..AD.AIKSARAVHLA--...---TG 130 ...NGEMVSAIAD....MKSIGAMNT..DFID.....SK..RE.IFENAEYTVLD--...---SD 131 ...SGDNSIVVSP....GANGRLAPG..D-VR.....AA..AS.LFHASRVVSTQ--...--LEI 132 dt.NGSTMIPEAG....FTVSQTNKV..NLLK.....QI..AK.KVKKEDMVVIAGS...PPPHY 133 ...DGERSMNTYL....GACVELGPE..DV--.....-E..DD.VVAQSKVTYFEGYl..WDPPR 134 ...RDTFPLLFVR....ENCADMAVR..A-DG.....ID..EG.FIAGCRALAITGTh..LSTPT 135 ...GRVSDLNGPG....PEADERAQA..ALLE.....RL..DR.LAGEHELAVVAGS...LPRGV 136 ...EGDPSIFYFR....KNSAAANFS..V-ED.....LN..KV.NLDGVKHVHITGIfp.ALSES 137 ...EDNQTTYFYW....GASSKFKEL..EPEP.....VD..FV.HLATADCVYNA--...----- 138 ...DGDRHFAGFGeyhtGDFADTAMQ..G-ET.....IP..ES.LFTSAQYLVMGTIa..LAYAP 139 ...HQQLLRLDFE....EDFNNVDCK..DLLA.....KL..ES.AVKNYGALILSDY...--GKG 140 ...TGEMLVAIND....MNISNAITA..EYLA.....QH..GE.FIQRAKVIVAD--...--CNI 141 ...NGERDFVFNR....GADGLLRYD..E---.....IN..LD.KVYSNKIIHFGSAta.LLGGE 142 ...DGENTIIVIP....GANASVTAE..F-VD.....KH..SQ.LIENAGIVLLQ--...--GEI 143 ...KGERIIVNYP....SPDLLPDAD..WLND.....ID..--.-FSQWDVVLAD--...---VR 144 ...EGIPVFSINE....GVAWDVITP..DEKQ.....FE..AL.AGDEWDVFCFGTLa..QRSEE 145 ...DGENNIVVIP....GANSLVNCD..Y-VS.....SQ..SA.LLAEAGILLLQGE...IPADG 146 ...KGERIIINYP....SPDLLPDAE..WLEE.....ID..--.-FSQWDVVLAD--...---VR 147 lqrHGFCSRADFK....EEPAFSWIT..DLSD.....EV..KM.AIRQSKVLFCNGY...DFDDF 148 ...NGERDFVFNR....GADALFTLE..D---.....ID..QE.KLNEAKILHFGSAta.LLSDP 149 ...SQRPSKVVYD....RAHSAISEA..KRED.....FD..WEkILDGARWFHFSGItp.PLGKE 150 ...KGERIIINYP....SPDLLPDAE..WLEE.....ID..--.-FSQWDVVLAD--...---VR 151 ...KGERIIINYP....SPDLLPDAE..WLEE.....ID..--.-FSQWDVVLAD--...---VR 152 ...EGDNSIVVVK....GANDDITPA..YALN.....AL..-E.QIEKVDMVLIQ--...--QEI 153 ...ASPSFLLYDD....VAYFNMTLN..D---.....IN..WD.IVEEAKIVNFGSVi..LARNP 154 ...NGERDFTFMR....GADGEYHFN..S---.....ID..LS.KIKTNDLIHFGSAta.LLSSP 155 ...DNNQITFFLW....GAAKHYKEL..NPPN.....F-..--.---NTEIVHIA--...---TG 156 ...GHATYAFYDE....NTAGRMITE..A---.....EL..PA.LGADCEALHFGAIs..LIPEP 157 ...GHASYAFFDE....NTAGRMITA..E---.....HL..PA.LGDFCEALHFGAIs..LIPEP 158 ...GHATYAFYDE....NTAGRMITE..A---.....EL..PA.LGADCEALHFGAIs..LIPEP 159 ...TGEMLVAIND....MNISNAITA..EYLA.....QH..RE.FIQRAKVIVAD--...--CNI 160 ...DQVTDLNFPG....IAAGPADLD..AVAA.....TL..TElLAQGLDWVALCGS...LPAGI 161 ...RDNRIIVTKG....AN-E-HVTP..DYVA.....AF..EQ.ELAASDVVLLQ--...--LEI 162 ...HQQLLRLDFE....EDFNNVDCK..DLLA.....KL..ES.AVKNYGALILSDY...--GKG 163 ...KQEYKLVNPG....SYIPDECKK..QIIT.....II..-S.QLPDAEYLVISGS...LPQGI 164 ...DNNQITAFHP....GAMMRSYEN..H---.....--..--.-VKDVPGVTLG--...LVGPD 165 ...KQEYKLVNPG....SYIPDECKQ..QIIT.....II..-S.QLPDADYLVISGS...LPQGI 166 ...KGRNIIVVNR....GANYYLSED..DLNN.....SL..--.---EGDILLMQ--...--LEI 167 ...AKPSFILYDE....VAYFNIKLS..E---.....VP..WE.ILESSKIVHFGSVl..LAREP 168 ...EDKRIVKYPG....ANRFKEVKE..N---.....--..--.YLKLARHLHLS--...---SN 169 ...SGQRTFFHSP....GANRLLDLP..AFDQ.....LDntMK.IFHLGYLLLLDSLd..MPDDV 170 ...DDFNRVYYYR....AGSAASRLG..V-ED.....IN..WA.YMKQAKIIHITGItp.LLSDS 171 ...DDQTVLAIND....THLLEQLTP..QLLN.....GS..RD.LLRHAGVVLAD--...--CNL 172 ...DGERSMNTYL....GACVELGPE..D---.....VE..TS.KVADARVTYFEGYl..WDPPR 173 ...DGERTFVTNR....NGSLWKLNI..D--D.....VD..FA.RFSQAKLLSLASIf..NSPLL 174 ...EGVSPMIFYR....SDCADMALA..P-ED.....ID..EA.FIASARSIVVTGTh..FSRPN 175 ...DGERTFVTNR....NGSLWKLNI..D--D.....VD..FA.RFSQAKLLSLASIf..NSPLL 176 ...RDTFPLIFYR....DNCADMAIT..A-QD.....FS..EQ.YIASARSLAITGTh..LSHPN 177 ...DDETVLAIND....THLLEQLSP..QLLN.....GS..RD.LLRHAGVVLAD--...--CNL 178 ...HQQLLRLDFE....EDFQNVTSD..ALLQ.....KL..DS.ALQNYGALVLSDY...--GKG 179 ...DAQRTMLAYQ....GTSSVVNYD..S---.....CL..AS.LIAKTNVFVVEGYl..FELPD 180 ...DAQRTMLAYQ....GTSSVVNYD..S---.....CL..AS.LIAKTNVFVVEGYl..FELPD 181 ...DDQTVLAIND....THLLEQLTP..QLLN.....GS..RD.LLRHAGVVLAD--...--CNL 182 ...DAQRTMLAYQ....GTSSVVNYD..S---.....CL..AS.LIAKTNVFVVEGYl..FELPD 183 ...QTNTRTCIYT....PGYPPLLPD..DLTEs....LL..LD.VLDGVRVLYVN--...---GR 184 ...GEQYRFVMPG....AALNEDEFR..QLEE.....QV..LE.-IESGAILVISGS...LPPGV 185 ...DAQRTMSTYL....GACVELNPA..D---.....VD..PD.IIEAAQISYLEGYl..FDPPE 186 ...NGERPVLHVL....GANATYRLE..D---.....IH..WD.VIASADILHFGGTy..LLPGL 187 ...GQATYAFYDE....GTAGRMITT..A---.....DL..PD.LGDDCEALHFGAIs..LIPSP 188 ...EDKRIVKYPG....ANRFKEVRE..D---.....--..--.YLKLARHLHLS--...---SN 189 ...NQQVLRFDEEei..KPLDETERA..GLIR.....HF..RA.ALAGAEIVILSDY...GKGIL 190 ...GGELLLAVAA....MDVMEHLTP..AALR.....GL..RA.SLRGAAWVVAD--...--GNL 191 ...AGDRTFAGFG....QYDTSEFAD..THLQakq..LP..ES.VFQEADFLILGTLe..LAYPD 192 ...SHQMLRVDRE....DRSPGDGAA..L-LA.....AF..ET.RLASADVVVLSDY...AKGVL 193 ...EDNSIVVVQG....-ANALVNES..V-VN.....RS..KD.LLIKADMVVLQ--...--LEI 194 ...NDTTDINLPG....LRLGPAHLQ..GVAD.....HL..AP.LLRPGLPVVLSGS...LPAGL 195 ...QGNRALYVDP....GVNDTLSMD..EVRE.....E-..--.-ALKTRLLHLTSF...--AGS 196 ...VSRGSKVVYD....RAHSAMAEI..QSGM.....VD..WKkVFAGAEWFHWTGItp.AITQS 197 ...DGERTFVTNR....NGSLWKLNI..D--D.....VD..FA.RFSQAKLLSLASIf..NSPLL 198 ...KERTLCTHLG....ACGSFRIPE..N---.....--..WT.TFASGALIFYATA...YTLTA 199 ...NGEVAAGVAG....VDAVENFLTp.EWIQ.....RF..EY.NISSARLLMVD--...--ANL 200 ...GGQRAMISDG....AANRQLDPA..KLKK.....KD..--.-VESADALIISAYs..LTEGP 201 ...NGEVAAGVAG....VDAVENFLTp.EWIQ.....RF..EY.NISSAPLLMVD--...--ANL 202 ...KERTLCTHLG....ACGSFRLPE..D---.....--..WT.TFASGALIFYATA...YTLTA 203 ...KERTLCTHLG....ACGSFRLPE..D---.....--..WT.TFASGALIFYATA...YTLTA 204 ...AHPPQYFFIG....ENSADLAFD..T-GV.....LP..DG.WIEAAQIVHFGSLs..LARQP 205 ...KERTLCTHLG....ACGSFRIPE..D---.....--..WT.TFASGALIFYATA...YTLTA 206 ...DGSPQYNFRG....EGCADRLLE..V--A.....HL..PV.LGDEVRGLHIGSFs..LVVQP 207 ...NGERPVLHVL....GANATYRLE..D---.....IH..WD.VIASADILHFGGTy..LLPGL 208 ...AKPEFILYDG....VAYFNLRKE..E---.....IQ..WD.FMRDAELLHFGSVl..FAREP 209 a..SGSRTILYYD....RSLPDVSAT..DFEK.....VD..--.-LTQFKWIHIEGRnasEQVKM 210 ...NQQLLRIDWE....DRSYISGKA..L---.....--..EK.ILDVIKNLQVDGI...IVSDY 211 a..SGSRTILYYD....RSLPDVSAT..DFEK.....VD..--.-LTQFKWIHIEGRnasEQVKM 212 ...TGDRTFFHYV....GAMAEYQAA..HILQ.....ID..--.--HPAKIAHIAYLpl.LPKLL 213 ...QTKTRTCIHT....PGDPPMLPT..DLSQs....SM..LS.ALDRASIVYFD--...---VR 214 ...SGSAQYQFRG....EGCADRQVR..L--E.....HL..PT.LDGRIRGLHVGSYt..LVVTP 215 ...NHHITRVDYEsrt.PVDAELEK-..RLLG.....MF..ME.IANAVDAVVLEDY...NKGVL 216 s..NGNRTIVLHD....TSLPDVSAT..DFEK.....VD..--.-LTQFKWIHIEGRnasEQVKM 217 ...DNNQITAFHP....GAMMRSYEN..H---.....--..--.-VRDVPGVTLG--...LVGPD 218 ...QTKTRTCIHT....PGDPPMLPT..DLSQs....SM..LS.ALDRASIVYFD--...---VR 219 ...QEETELNGQG....PIISREQLE..E-LK.....TK..LS.QLTAEDTVVFAGS...APANL 220 ...SGQRTFFHSP....GTNRLLDLP..AFDG.....LD..--.--TSFKIFHLGYLl..LLDSL 221 ...DGNNRVWGLC....EKGVSMFQL..D--T.....AD..LE.YLGKFDLAHTGET...SQLDS 222 ...RGENLIVTGA....SCAAAFDPL..A-DG.....GF..AT.SIEHGDIVVMQ--...--GNL 223 ...SGNRTMRPCL....SSAVKIQAD..ELSK.....--..-E.DFTGSKWLVLR--...-YAVL 224 ...EKTTEINDLS....PLITDANLT..ELLT.....FL..KA.NVKNNDLVIIN--...--GRF 225 ...GARASRVTYS....NRLESSFNT..ACEEmy...QF..EE.IAKEIDIVHFCGItl.AMNDT 226 ka.GGQNRILIVE....GANSKTIYDpkQLCE.....IF..PE.GKEEEEYVVFQ--...--HEI 227 ...SQRPAKLVYD....RKDSAIAKA..KRED.....FN..WDkIFDGADWFHFSGItp.ALSDE 228 ka.GGQNRILIVE....GANSKTIYDpkQLCE.....IF..PE.GKEEEEYVVFQ--...--HEI 229 ...GTTTKLNGPG....APLSEQKLR..SLEK.....VL..IDaLRPEVTWVVLAGS...LPPGA 230 ...NGDQYKINVA....GANVFLTAK..D-VT.....RA..KK.SFQDAKVLLCQ--...--LET 231 ...TRPPQYRFLG....ENSADLHFD..P-TR.....LP..GG.WLGAARWLHVGGIs..LARWP 232 ...KGNRAILVDP....GVNDTIAYD..E---.....ID..VD.SARKYDLIHLTSFi..--CKN 233 ...EGERTFFVEP....NAAGKPFVE..V---.....--..--.--DGGDYLYLD--...--PFP 234 ...GQATYTFYDE....NTAGRMLTI..D---.....DL..PS.LGNEIEAMLFGAIs..LISEP 235 ...AGDRIFVHEDf...GACAGYRPD..A---.....GE..IE.LLKTMDHVHIG--...----- 236 ...DNPTLYANIG....ASAQFEVQT..LSHAvs6gqSF..LR.PVERKQILYVEGF...FVPQ- 237 ...SGTRTIIHCN....KDYPQTTYE..DFSK.....IN..--.-LSQYGWVHFEA-...----R 238 ...QGDRIFVRSNk...GGIQSRLRL..AFQE.....KD..VS.FISGHDLLHTSVY...SRLEN 239 ...SGNRTMRPCL....SSAVKLQAN..EFKK.....ED..--.-FKGSKWLVVR--...-YARQ 240 ...NGSISMVRKL....GSSILLDKE..D---.....-I..KK.VFGLFDVIHFASI...SPDIV 241 ...NGDLQTSISK....QPDEAMMEQ..CILR.....RI..DT.VFAESTAVAID--...--LDL 242 ...SGRRSIYSYM....GANAELEIG..TPEG.....RC..--.-IRAADAVHLS--...---GC 243 ...EGSDIYYYRS....GSAATLMDG..EYAE.....RI..AA.V--RPRWIHLTGVtp.ALSEN 244 ...NDKPLAVDPG....VNRKEMKLP..S---.....--..--.-LSEYDLVFVT--...--GEI 245 ...AQTTEINDVT....PLIEEQAVH..EMIA.....YL..KA.NVKPNDLLVLN--...--GRF 246 ...EKTTEINDLS....PLITDANLT..ELLT.....FL..KA.NVKNNDLVIIN--...--GRF 247 ...NGEVAAGVAG....VDAVVTIVS..P---.....NQ..DE.LIAMANALCAK--...----- 50 160 170 180 190 | | | | | 1 NEG.IC.....NELVRLARER.....GVFVFVEQ.....TPRLLER.....IYEGPE..FPNVVK 2 CRS.TQ.....LVAMKIAKAA.....GSLLSYDP.....NLRLPLWps9keIMSIWN..LADVIK 3 CRS.TH.....LAAMDIAKRS.....GSILSYDP.....NLRLPLWps9sgIMSVWN..LADIIK 4 CRS.AH.....LRAMEIAKEA.....GALLSYDP.....NLREALWps9tkILSIWD..QADIVK 5 SPE.AF.....TDWMTRLRSQ.....CPCIIFDS.....SREALV-.....-AGLKA..APWLVK 6 CRS.AH.....MKAMEVAKEA.....GALLSYDP.....NLREPLWps9tqIMSIWD..KADIIK 7 PLE.TV.....GHVLRRAHAL.....GKTVILNP.....APATRDV.....PAEWLP..LVDYLV 8 SPE.AF.....TDWMTRLRSQ.....CPCIIFDS.....SREALV-.....-AGLKA..APWLVK 9 CRS.AH.....LKAMEVAKEA.....GALLSYDP.....NLREPLWps9tqIMSIWD..KAEIIK 10 CRS.AH.....LKAMEVAKEA.....GALLSYDP.....NLREPLWps9tqIMSIWD..KAEIIK 11 SPE.LF.....ADWLNQLHQA.....GVKVVLDS.....SNAALT-.....-AGLKA..KPWLVK 12 PLD.TV.....IAAAKLAKQH.....QTQVILNP.....APARKL-.....PDELLT..LVDMIT 13 PKT.FY.....KEIIKEVKNK.....DLKIILDA.....DNQALF-.....-YGIEE..RPFMIK 14 PVE.TV.....YHTIEFAAQN.....GIETILNP.....APAAANL.....DPERIR..QVTFLV 15 PLS.GV.....ELAAQIAKKN.....GVKVVLNP.....APAQIL-.....SDELLS..LIDIIT 16 DEK.GN.....RRAFEIARSH.....GVTTFLNP.....APGDPNM.....DKTILE..LVDIIC 17 CKS.AH.....ISAAKAAKEA.....GVILSYDP.....NLRLPLWps9eeILSIWE..TADIIK 18 PHD.TY.....EKIAEACKQQ.....NARVVLDI.....SGEALLK.....ATEM--..KPFLMK 19 PVP.AV.....IAAAQAARSN.....NITVILDP.....APAPSDL.....PTELYS..FVDIIT 20 PEN.IT.....IEAFKIAKEN.....GKVTILNP.....APAKKI-.....KDELLN..YTDIIV 21 SRS.ST.....FAAIAQMKEV.....GGYVSFDP.....NLREEVWse9atVMRAVG..LADVVK 22 NPD.DF.....TDWMKRLRSQ.....CPCIIFDS.....SREALV-.....-AGLKA..SPWLVK 23 SRE.AV.....FLALEYARKH.....DVVVFFDV.....DYRPYTWqs9vyYNLAAE..KSDVII 24 SVD.DF.....TAWLSQLNKN.....NIKLILDT.....SQQAFA-.....-SGIQA..KPWLVK 25 SRE.AV.....LKAIRLAKRN.....DVKVVFEL.....DYRPYSWet9vyYSLVAE..QSDIVI 26 GND.FY.....ITIIEILNKN.....GANFTLDS.....SGETFS-.....-KSLKY..KPFLIK 27 PKN.IY.....GTLTKIAKEE.....GSFVILDA.....EGELLS-.....-EGIKE..NPYIIK 28 QLE.TV.....YHAIEFGKKN.....GIEVLL-I.....RLRHCVS.....RYVYAC..KCDFFI 29 CRT.AH.....MAAMKTAKDA.....GVLLSYDP.....NVRLPLWps9egIKSIWN..EADIIK 30 SRE.AA.....LKALRLAKKN.....GTVVIFDV.....DYREYNWkn9iyYSIVGK..ESDIIM 31 SRE.AV.....LKAVQYAKKH.....QVKVVFEL.....DYRPYTWqs9vyYSLVAE..QSDIVI 32 ARE.AC.....LEGARRMREA.....GGYVLFDV.....NLRSKMWgn9elIARSAA..LASICK 33 QLE.TV.....YHAIEFGKKH.....GIEVLLNP.....APALREL.....DMSYAC..KCDFFV 34 SRG.AA.....LHAMHAIRQA.....GGWVSFDP.....NLRADLWpd9rsVAQAFE..LADIIK 35 KLE.KL.....TQLISAAQKQ.....GIRCIVDS.....SGEALS-.....AALAIG..NIELVK 36 KLE.KL.....TQLISAAQKQ.....GIRCIVDS.....SGEALS-.....AALAIG..NIELVK 37 ALA.SV.....QQMIQLARKA.....GVPVLIDP.....KGTDFE-.....---RYR..GATLLT 38 ALA.SV.....QQMIQLARKA.....GVPVLIDP.....KGTDFE-.....---RYR..GATLLT 39 RPD.TT.....LKTVEIAKKR.....SITVSWDP.....GRVLSKMgaer.LANIIS..KVDIIF 40 ALT.SV.....QTMISLARQA.....GVPVLIDP.....KGTDFE-.....---RYR..GATLLT 41 PDD.YY.....QKLIGIANLN.....GKKTVLDC.....SGNALEA.....VLKGDS..KPTVIK 42 ALT.SV.....QTMISLARQA.....GVPVLIDP.....KGTDFE-.....---RYR..GATLLT 43 ALT.SV.....QTMISLARQA.....GVPVLIDP.....KGTDFE-.....---RYR..GATLLT 44 GND.FY.....DKIIQICKEK.....QANFMIDT.....TGQELL-.....-DALPN..RPILIK 45 KVE.KL.....TQLISAAQKQ.....GIRCIIDS.....SGDALT-.....AALALG..DIELVK 46 KVE.KL.....TQLISAAQKQ.....GIRCIIDS.....SGDALT-.....AALALG..DIELVK 47 CRS.AH.....VAAMRAAKSA.....GILCSYDP.....NVRLPLWps9agILSIWK..EADFIK 48 SRE.AV.....LKAVHLAQKN.....DVIVAFEL.....DYRPYTWkn9vyYSLVAE..QADVII 49 PIE.TV.....KFVVDLCYSR.....GIKVILNP.....APAYEL-.....PDTVLE..KVYILT 50 LKN.TY.....FKLLEIGRKN.....GNFISFDP.....NYRDMLIk11edCKKFIS..SCDFLK 51 RTE.LI.....LKAKEIAREI.....GASISVDG.....GTALARKglei.VRAAVE..GVDVVF 52 GND.FY.....NKIIQICKEK.....KAEFMIDT.....TGQELL-.....-DALPN..RPILIK 53 SRE.AV.....LKAVSLARKN.....DVVVAFEL.....DYRPYTWkn9vyYSLVAE..QADVII 54 ADA.AQ.....RKAIRIAKES.....GARIVFDI.....DYRPNLWg21ahLKTVLG..DCDLIV 55 PAD.TY.....VRLLARLNRR.....GARTLLDT.....SGAPLTHal...AAPREA..LPTAIK 56 SRS.ST.....FAAIHRIKAE.....GGFFSFDP.....NLRESLWns9tvVNQVVA..LADVLK 57 GNA.VY.....KELLPLVRQS.....GAQVVCDF.....EGQTLI-.....-DALTY..NPLLVK 58 PED.SW.....AQLQAQASAA.....GARVLLDT.....SGAPLVAal...AAAPVA..MPYAVK 59 TEA.AV.....LKALKLAREN.....GAKTALDI.....DYRPNLWg21akLQSTLH..LFDLIV 60 SPA.AS.....LEALTMARRS.....GVKTLFNP.....APAMADL.....DPQFYT..LSSIFC 61 PKD.LY.....LQIQKRVSKK.....NVKVVVDT.....SGKALL-.....-EAIKN..KPFLIK 62 APD.FY.....TELVAKLRGA.....GKFVALDT.....SGAALTA.....ALTANV..LPHLVK 63 TPA.TS.....LEALTMARRS.....GVKTLFNP.....APAIADL.....DPQFYT..LSDVFC 64 SRS.TT.....FAAMESIRSA.....GGRVSFDP.....NIRPDLWqd9acLDRALH..MANVVK 65 PLA.TV.....DAALDQARAA.....GAITVLNT.....APFQGD-.....ATAFLG..KADYVV 66 GNV.IY.....KDLISLTRQT.....GAQVVCDF.....EGQTLI-.....-DSLDY..QPLLVK 67 GNV.IY.....KDLISLTRQT.....GAQVVCDF.....EGQTLI-.....-DSLDY..QPLLVK 68 PVD.YY.....SQMIAICKQH.....QVPIVLDC.....SGQALLE.....VLNGAA..KPTVIK 69 GED.FY.....ERLIAKVQKQ.....KATFVMDV.....DGQKLL-.....-DSLPA..HPLLIK 70 GNA.VY.....KELLPLVRQS.....GAQVVCDF.....EGQTLI-.....-DALAY..NPLLVK 71 KLE.KL.....TQLISAAQNQ.....GIRCIIDS.....SGEALS-.....AALAIG..NIELVK 72 SRS.ST.....FEAIKRAKAA.....GGFISFDP.....NLRDEVWqd9avVMKAVA..MADVVK 73 PDD.YY.....QKLIKIANLN.....GKKTVLDC.....SGNALEA.....VLKGDS..KPTVIK 74 SPE.AF.....TDWMTRLRSQ.....CPCIIFSD.....DREALV-.....-AGLKA..APWLVK 75 PVP.AL.....NHLFALKSVK.....EFDLIFNP.....APVRAGL.....SPAAWR..SVDFVT 76 PHE.AN.....LAVAKAVRAA.....GGTVLLDP.....APVGDASq....MADLIA..LSDIIS 77 SPE.SV.....LKVARYAAEN.....NRTFTLNL.....SAPLLSQffkeaLMEVMP..YVDILF 78 GNQ.IY.....ERLIPLVRQT.....GAQIVCDF.....EGQTLL-.....-DALDY..QPLLVK 79 PPD.AV.....ERALLLGQRL.....GKTVILNP.....APAAGPL.....PTPWLA..ACDYLI 80 SRS.AY.....LKVMETFLEE.....GKPVSYDP.....NVRPSLIed9kdFLEISS..KVDIVK 81 GED.AY.....NEIANSISN-.....DVKLIIDT.....SGKPLRK.....ILRL--..NPFLIK 82 PKN.VY.....AKLIEKANKN.....DKKFLLDT.....SGDLLK-.....-EGIEA..KPFLIK 83 PSD.AY.....AQIAQITAQT.....GAKLVVDA.....EKELAES.....VLPF--..HPLFIK 84 SPE.SV.....LKVARYAAEN.....NRVFTLNL.....SAPFISQffkeaLMDVMP..YVDILF 85 SPE.SV.....LKVARYAAEN.....NRVFTLNL.....SAPFISQffkeaLMDVMP..YVDILF 86 PHE.TN.....LAIAKFCKEN.....AIKVLYNP.....APARKT-.....DLEMID..FVDYIT 87 PFE.TT.....LEC---AKRF.....NGIVIFDP.....APAQGI-.....NEEIFQ..YLDYLT 88 PEE.SI.....RYITELCYNN.....NIPVVVEPv....SIDKAKK.....LKNVLD..KIDYIT 89 TEA.AV.....LKALRLAREN.....GSRTALDI.....DYRPNLWg21akLQSTLH..LFDLIV 90 PDD.YY.....QKLIGIANLN.....GKKTVLDC.....SGNALEA.....VLKGDS..KPTVIK 91 NIE.AL.....TEFIRLGKQE.....NKMIMLNP.....APYTKQ-.....VTHLLS..DIDIIT 92 PND.YY.....EKLIQLASDE.....GVAVVLDC.....SGAPLET.....VLKSSA..KPTAIK 93 PDS.IN.....IQVAKAVKKA.....GVPVILDV.....GGMDTPI.....PNELLD..SIDILS 94 PDS.IN.....IQVAKAVKKA.....GVPVILDV.....GGMDTPI.....PNELLD..SIDILS 95 SPE.SV.....LKVARYAAEN.....NRIFTLNL.....SAPFISQffkesLMEVMP..YVDILF 96 PTT.FY.....ESIAAFGAEK.....GIRVVVDA.....SGSALQ-.....-HVVKN..KPFLIK 97 PID.AA.....MRALEIARGA.....GVTTILNP.....APAAKL-.....PDRVYT..LCDYLT 98 AAD.YY.....QRVADICRRS.....STPLILDT.....SGGGLQ-.....--HISS..GVFLLK 99 TLA.NI.....QNIIDLAKKM.....SIPILIDP.....KGIDFK-.....---KYS..GASLLT 100 IAR.CT.....LDGMRRARAD.....GAIVSLDL.....NLRPMLWpq9plLWEALA..LADVVK 101 SPQ.RC.....AGWIAQLRSM.....NKKVLFDS.....SRDALL-.....-AGLDA..KPWLIK 102 NRK.TL.....KRLLSEIKAK.....HFFYDVNLra...GFYRKEW.....ILSSLE..RCTILK 103 SPE.SV.....LKVARYAAEN.....NRIFTLNL.....SAPFISQffkesLMEVMP..YVDILF 104 PSD.AY.....AQIAQITAQT.....GAKLVVDA.....EKELAES.....--VLPY..HPLFIK 105 ESR.FY.....AEIIELCQQK.....RCEVILDI.....SHPVLRQ.....LLEL--..RPLLIK 106 PED.SW.....AQLQAQASAA.....GSTRPARH.....QRCAAVAal...AAAPVA..MPYAVK 107 PVD.YY.....ASLVELANQA.....GKHVVLDC.....SGAALQA.....VLESPH..KPTVIK 108 PQT.IY.....RSMTQIAKER.....GAFVAVDT.....SGEALH-.....-EVLAA..KPSFIK 109 PSD.LY.....QTISTYCDEN.....EILFVVDA.....TKDVLL-.....-STLSA..KPFLIK 110 SPE.SV.....LKMARYAAEN.....NRTFTLNL.....SAPFISQffkeaLMAVMP..YVDILF 111 NQD.YY.....AQIIERCQNK.....GVPVILDC.....SGATLQT.....VLENPY..KPTVIK 112 ---.--.....-----KIAQI.....AGFVSFDP.....GQDLVTYsqek.LETILA..HTDILF 113 PVG.AY.....AGLVRVARAA.....GVPVLLDT.....SGEPLR-.....-RGLAA..RPDLIK 114 ART.AT.....RHAVSLAKKN.....GLMISYDP.....NLRLNLWed9llITSMLG..EADVLK 115 NQD.YY.....AQIIERCQNK.....GVPVILDC.....SGATLQT.....VLENPY..KPTVIK 116 PVD.YY.....ASLVELANQA.....GKPVVLDC.....SGAALQA.....VLESPH..KPTVIK 117 SKD.FY.....VKMLSICNKK.....DKRVVLDC.....SGEELRQ.....VLKNDS..KPFAIK 118 TLV.NV.....KKIITLAKKM.....SIPILIDP.....KGLDFK-.....---KYS..GATLLT 119 PIE.LI.....REAVEKAKEL.....GLTVSFDP.....GEMEVP-.....-RDVEK..ELDILM 120 NEG.IC.....NELVRLARER.....GVFVFVEQ.....TPRLLER.....IYEGPE..FPNVVK 121 SRE.TV.....LDVIKRVK--.....-TIVSFDV.....NLRLDLWk10rtIEEAIK..LADIVK 122 RPA.TA.....ARLTALAREH.....DATVSFDP.....GRRLRDRd....YGDALA..RTDILF 123 ALT.SV.....QTMISLARQA.....GVPVLIDP.....KGTDFE-.....---RYR..GATLLT 124 SRS.TT.....FAALEAIKRA.....GGYVSFDP.....NIRSDLWqd9dcLDRALA..LADAIK 125 TLS.DF.....KELLRTVKAT.....GAFLGCDN.....SGEYLNL.....AVEM--..GVDFIK 126 APS.WY.....ADLVARAHAA.....GVRIALDT.....SGPALL-.....-RALRE..RPDVVK 127 SPE.SV.....LKMARYAAEN.....NRTFTLNL.....SAPFISQffkeaLMAVMP..YVDILF 128 PEE.TV.....DEVCKYCHSH.....DIPIILNP.....APARPL-.....KQETID..HATYLT 129 DPS.FN.....CRCGEFARSL.....GKIISFDP.....GQDLHMYsrsq.LERAVG..VCDILF 130 NPE.IM.....EYLLKNFKDK.....TNFILDPV.....SAEKASW.....VKHLIK..DFHTIK 131 PLE.TV.....VEVVRSLAP-.....DSRFVLNP.....SPPRPL-.....PQEVLT..ACDPLI 132 TLS.DF.....KELLRTVKAT.....GAFLGCDN.....SGEYLNL.....AVEM--..GVDFIK 133 AKD.AI.....REAARIAHAH.....GRETAMTL.....SDSFCVHry7flELMRSG..TVDIVF 134 TRE.AS.....LTALAYARRH.....GAVRILDI.....DYRPVLWg21rqLQQALG..EFDLLV 135 EPE.WL.....GELLRRLRRL.....GLKVAFDS.....SGAALR-.....-EGVKA..APWMIK 136 TKE.AT.....YKLLELAKER.....NITTTFDT.....NLRPQLWns9stINDIAF..KSDILL 137 ---.--.....-----KIAQI.....AGFVSFDP.....GQDLVTYsken.LETILA..HTDILF 138 SRT.AT.....ERLVALAKKH.....QVKIFLDV.....NWRSVFWdd9erIPALIT..HAQILK 139 TLK.DV.....QKMIQIARKG.....NVPVLIDP.....KGTDFE-.....---RYR..GATLLT 140 SEE.AL.....AWILDNAA--.....NVPVFVDPv....SAWKCVK.....VRDRLN..QIHTLK 141 MTD.TY.....LKIMEEAKKR.....GIIISFDP.....NYRDNLWe10aiSRKCIE..LADFVK 142 PAD.GF.....ERAVDLSQ--.....-GRVVINL.....APVVPV-.....GHDQLR..RADPLL 143 WHD.GA.....KQAFTLARQA.....GVMTVLDG.....DITPQD-.....ISELVA..LSDHAA 144 NRK.TL.....KRLFQEIKTK.....HFFYDVNLra...EYYTEEW.....ILSSLE..HCTILK 145 FKE.AI.....HHTM------.....-GRVVVNL.....APVIEV-.....EKSALL..EADPII 146 WHD.GA.....KKAFTLARQA.....GVMTVLDG.....DITPQD-.....ISELVA..LSDHAA 147 SPS.FI.....MSTIDYAAKV.....GTAIFFDP.....GPRGKSLs10raLAHFLR..MSDVLL 148 FCS.AY.....LRLMSIAKDN.....GQFISFDP.....NYREDLWr10svAKKAIA..VSDFVK 149 LPL.IL.....EDALKVANEK.....GVTVSCDL.....NYRARLWtk8kvMIPFME..YVDVLI 150 WHD.GA.....KKAFTLARQA.....GVMTVLDG.....DITPQD-.....ISELVA..LSDHAA 151 WHD.GA.....KKAFTLARQA.....GVMTVLDG.....DITPQD-.....ISELVA..LSDHAA 152 PEE.TV.....DEVCKYCHSH.....DIPIILNP.....APARPL-.....KQETID..HATYLT 153 SRE.TV.....MKVIKKIKGS.....SL-IAFDV.....NLRLDLWr10kvLEESIK..LADIVK 154 LKD.TY.....FQLLQHARES.....GQFISFDP.....NYRNALItn9qdCLTFIK..HAHFVK 155 DPE.FN.....LKCAKKAYGN.....NL-VSFDP.....GQDLPQYskem.LLEIIE..HTNFLF 156 CGS.TY.....EALMTREHET.....RV-ISLDP.....NIRPGFIqn9arIRRMAA..MSDIVK 157 CGS.TY.....EALMAREHEK.....RV-ISFDP.....NIRPGFIkd9grMNRMAA..MSDIVK 158 CGS.TY.....EALMTREHET.....RV-ISLDP.....NIRPGFIqn9arIRRMAA..MSDIVK 159 SEE.AL.....AWILDNAA--.....NVPVFVDPv....SAWKCVK.....VRERLS..QIHTLK 160 GAE.AY.....AELAALARKG.....GARVALDT.....SGPALG-.....-LALAA..RPDIVK 161 PLE.TV.....AYVLEFCAKH.....HVTTVLNP.....APAQKL-.....PDAAWT..DATYIS 162 TLK.DV.....QKMIQIARKA.....NVPVLIDP.....KGTDFE-.....---RYR..GATLLT 163 ESR.FY.....AEIMHICQQK.....NIGVILDI.....SHPSLRQ.....LLEF--..KPLLIK 164 GRE.GM.....IQNAEEFAAA.....GIPFIFDP.....GQAMPLFngpe.LRQFIE..QAQYVV 165 ESR.FY.....AEIMHICQQK.....NIGVILDI.....SHPSLRQ.....LLEF--..KPLLIK 166 RES.VV.....KKA---AKEF.....NGIKILNP.....APANLK-.....DTEILS..LVDIIT 167 SRG.TM.....IKVIETLKEK.....SL-VSFDV.....NIRKDLWrs9etLKRVLS..NVDILK 168 PLP.LV.....EKAVNLAKNL.....GLTVSFDP.....GEMEVP-.....-KHIEE..KIDILM 169 YGT.RS.....ARLLAQMRDT.....GFETSLDLvsrkgDPRYQPL.....VLPALR..HLDYLV 170 CYE.LC.....HAVLDFAKEN.....GIFASFDP.....NLRMKLLan9erLLALAS..KADLVM 171 TAE.AL.....EWVFTLADE-.....-IPVFVDTv....SEFKAGK.....IKHWLA..HIHTLK 172 AKE.AI.....VMASKIAHES.....GRQMAMTL.....SDPFCVDry7flQLMRSR..TVDIVF 173 DGK.AL.....TEIFTQAKAR.....QMIICADMi....KPRLNETldd..ICEALS..YVDYLF 174 SDA.AQ.....RKAIRIMKAK.....GGKVVFDI.....DYRPNLWg21aqLKTVLP..DCDLIV 175 DGK.AL.....TEIFTQAKAR.....QMIICADMi....KPRLNETldd..ICEALS..YVDYLF 176 TRE.AV.....LTALRYARRN.....GVRTVLDI.....DYRPVLWg21aeLLAVFN..LFDVIV 177 TAE.AL.....EWVFTLAGE-.....-IPVFVDTv....SEFKAGK.....IKHWLA..HIHTLK 178 TLN.QV.....QKMIQLARQA.....NIPVLIDP.....KGTDFE-.....---RYR..GATLLT 179 TIR.TI.....TKACEEAHRN.....GALVAVTA.....SDVSCIErh6dfWDIVGN..YADIVF 180 TIR.TI.....TKACEEAHRN.....GALVAVTA.....SDVSCIErh6dfWDIVGN..YADIVF 181 TAE.AL.....EWVFTLADE-.....-IPVFVDTv....SEFKAGK.....IKHWLA..HIHTLK 182 TIR.TI.....TKACEEAHRN.....GALVAVTA.....SDVSCIErh6dfWDIVGN..YADIVF 183 SRE.AE.....LLLAQKAHSK.....NIPILINA.....EKKRTG-.....LDELID..LADYAI 184 KLE.KL.....TQLISLRKNK.....GSAASSTV.....LGQGLS-.....AALAIG..NIELVK 185 ARR.AF.....AKAAALAHGS.....DRKIALTL.....SDSFVVDrh6alLGFVET..QCDIVF 186 DGP.PT.....ATILKFAKEH.....GVTTTLDLlvn..-AQPDLLak...LEPALP..YIDYFM 187 CGE.TY.....EALLDREAAS.....RV-ISLDP.....NIRPGFIkd9arIKRMAA..KSDIVK 188 PLS.LV.....EKAVTLAKNL.....GLTVSFDP.....GEMEVP-.....-KNIEE..KVDILM 189 LDG.VA.....AELIAICREA.....GKPVLVDP.....KGRDYA-.....---RYA..GATAIT 190 PAD.TL.....PTLLALAAET.....GVRVVYEPv....SVPKAARlrp..ALAAGH..VPYAVT 191 SEK.AI.....HRALELAEQY.....DLKIVLDV.....NWRPVFWhd9qkIQEIFK..RVDFLK 192 TPA.VV.....RGAIDAAKAA.....GKPVIVDP.....KSRDFA-.....---RYD..GATLIK 193 PLE.TV.....KYVLAICQEH.....KIPVMLNP.....APAQVL-.....SEDILE..KATYIT 194 PDD.SW.....AQLQAQASAA.....GARVLLDT.....SGMPLVSal...DAAREA..LPYAVK 195 GIR.VQ.....REVLGVIDD-.....SVTVSLDP.....GHLYAERgase.LEGILE..RTDILL 196 AAD.VC.....LEAVKAASDL.....GITISTDL.....NYRAKLWk11eiMTELTS..HCDIVL 197 DGK.AL.....TEIFTQAKAR.....QMNICADMi....KPRLNET.....LDDICE..ALSYV- 198 TPK.NA.....LEVAGYAHGIp....NAIFTLNL.....SAPFCVElykdaMQSLLL..HTNILF 199 SSL.AL.....EASCKLAAES.....SVPVWFEPv....SVTKSQR.....IASIAK..YVTIVS 200 QRE.YA.....QKAIEIARGAkk...PVPVFIDL.....GTGAVEKvgtg.LVAEVR..GADYLT 201 SSL.AL.....EASCKLAAES.....SVPVWFEPv....SVTKSQR.....IASIAK..YVTIVS 202 TPK.NA.....LEVAGYAHGIp....NAIFTLNL.....SAPFCVElykdaMQSLLL..HTNILF 203 TPK.NA.....FEVAGYAHGIp....NAIFTLNL.....SAPFCVElykdaMQSLLL..HTNILF 204 LAA.HL.....LETATAVHAA.....GKRIAFDP.....NYRDAMAgp7ptLRRMAG..LASYIK 205 TPK.NA.....LEVAGYAHGIp....NAIFTLNL.....SAPFCVElykdaMQSLLL..HTNILF 206 IGD.TL.....LSLVKRESGK.....RL-ISLDP.....NVRLNPQpd9drVAELAK..HADLIK 207 DGP.PT.....ATILKFAKEH.....GVTTTLDLlvn..-AQPDLLak...LEPALP..YIDYFM 208 SRS.TV.....FEVLRAVKG-.....KVPISYDV.....NIRLDLWr10kdIEEALK..LADIVK 209 LQR.ID.....AHNTRQPPEQ.....KIRVSVEV.....EKPREE-.....LFQLFG..YGDVVF 210 AKGvIT.....EEVIKTIREK.....GVFYSVDP.....RPKH---.....-RELYR..KAYLMT 211 LQR.ID.....AHNTRQPPEQ.....KIRVSVEV.....EKPREE-.....LFQLFG..YGDVVF 212 DVE.VL.....KHTLTSLQQK.....GFLISIDLvsva.---NKQIftqq.ILPILP..YVDYVI 213 LHE.TA.....LVIAKEASRK.....KIPILVDT.....EKKRDG-.....LDDLLP..FADYVV 214 VAD.TL.....LALVRRESGR.....RL-VSLDP.....NVRLDPQpd9rrVEAFAS..HAHLIK 215 TPS.LI.....VSLIAACRER.....NKPVLVDP.....KLKGFF-.....---SYG..GCSVFK 216 LQR.ID.....AHNTRQPPEQ.....KIRVSVEV.....EKPREE-.....LFQLFG..YGDVVF 217 GRE.GM.....IQNAEEFAAG.....GIPFIFDP.....GQAMPLFngpe.LREFIE..QADYVV 218 LHE.TA.....LVIAKEASRK.....KIPILVDT.....EKKRDG-.....LDDLLP..FADYVV 219 GNA.VY.....KELLPLVRQS.....GAQVVCDF.....EGQTLI-.....-DALAY..NPLLVK 220 DVE.DTey6rsARLLALMSQL.....GYETSLDLvsregDPRYHLL.....VTPTLC..WLDYLT 221 QLP.AM.....RER-------.....-VAISFDF.....SDRSLDY.....AASVLP..YIKIAA 222 LPD.VT.....TSCLQAARSA.....GAMTILNP.....SPLAVG-.....STPCMD..AVSLAV 223 NLQ.VI.....QAAIRFAKQE.....GLSVSLDL.....ASFEMVRns6el-RQLLEsgNIDLCF 224 KFE.AL.....EKVLNLVFTL.....TENVVIDV.....DESKMLT.....LL-NQS..KPLVMK 225 VRH.HM.....KSLAKAVKEN.....GGTVVFDC.....NYRPSLWg11phYEEMLD..LADIVM 226 PDP.LS.....IIKWIHANRP.....NFQIVYNP.....SPFKAM-.....PKKDWE..LVDLLV 227 CAK.IT.....LDAVKAAKAK.....GLTVSIDL.....NYRENLWda8kaIRELLQ..YCDVAL 228 PDP.LS.....IIKWIHANRP.....NFQIVYNP.....SPFKTM-.....PKKDWE..LVDLLV 229 PVD.WY.....ARLTALIHSArp...DVRVAVDT.....SDKPLMAlges.LDTPGA..APNLIK 230 DMN.AT.....MCALRQFKGV.....S---LLHM.....SPMRKDI.....PNAMIG..LPTILV 231 LAD.TL.....LGVIEAARAA.....GVRISFDP.....NARIAHRhp7avFAAVTK..RADLLK 232 GLD.SL.....NSQKRIVEEF.....DS-VSFDP.....GMPYAERglgd.MEKILK..NTTIFL 233 SEH.SF.....EVQRKEAERF.....DGFVILNP.....GFPYSSLgfer.LKQILQ..HVDMLI 234 AGG.AY.....EEFMRREHAS.....RV-MMLDP.....NIRPNFIpd9rrIREMMA..MADIVK 235 WLD.DG.....GLLRRALSAA.....GVSVSQDV.....SVNAAAA.....DLE---..------ 236 RSD.VC.....DYIVQHLVRE.....RRRLALNL.....SAPYIVRknhqaMMKLAR..AAFFLF 237 NTP.HT.....LKMMQSIREYnq6gqGIIISLDF.....ETRYEQ-.....NQELCA..PCDFVV 238 DLP.QL.....CGL-------.....-VPVSFDF.....STNREDDy....LRRVCP..YVTYAF 239 NME.QI.....LEAIRIAKQE.....GLSVSLDL.....ASFEMVRdy7liDLLETG..NIDLCF 240 VRD.PY.....AKL-------.....---ITYDP.....GPNSSK-.....IPENFG..NADIIY 241 SVN.VL.....NETIELCREM.....KLPLYGVC.....GHLSVIEr....NRHLLQ..GFTGFI 242 YVE.VA.....QRVAEIRE--.....---VYFSP.....GRLLAGYgldv.LEPVLR..KTEVLF 243 CRE.AV.....ISLIELAGDT.....GASVSFDV.....NYRPSLWpa9qsLMAIAD..RCNVVF 244 PEK.TI.....RKICENTKN-.....---VILDV.....GPGARF-.....--DTSD..LNALVI 245 LQR.DL.....VKLLDVAFSL.....TKYVVLDV.....DEPQLLQ.....LLNQ-R..QPWLMK 246 KFE.AL.....EKVLNLVFTL.....TENVVIDV.....DESKMLT.....LL-NQS..KPLVMK 247 ---.--.....----------.....--------.....-------.....------..------ 200 210 220 230 | | | | 1 PDLRGNHASFLGVDL.....KTFDDYVKLAEKLAEKS.....QVSVVSYEVK.....N.DIVAT. 2 IS-EDEITFLTGG--.....DDPYDDDVVLQKLFHPNl....KLLVVSEGPN.....G.CRYYT. 3 IS-EDEISFLTGA--.....DDPNDDEVVLKRLFHPNl....KLLLVTEGSA.....G.CRYYT. 4 VS-EVELEFLTGI--.....---DSVEDDVVMKLWRPtm...KLLLVTLGDQ.....G.CKYYA. 5 PN-RRELEIWAGRKL.....PEMKDVIDAAHALREQGi....AHVVISLGAE.....G.ALWVN. 6 VS-DVELEFLTEN--.....-KTMDDKTAMSLWHPNL.....KLLLVTLGEK.....G.CTYFT. 7 PN-ETESELLCRLPV.....DSLESAGRAAERLREMGa....GRVIVTLGAQ.....G.ALLVG. 8 PN-RRELEIWAGRKL.....PEMKDVIEAAHALREQGi....AHVVISLGAE.....G.ALWVN. 9 VS-DVELEFLTGS--.....---NKIDDETALTLWHPnl...KLLLVTLGEK.....G.CRYYT. 10 VS-DVELEFLTGS--.....---NKIDDETALTLWHPnl...KLLLVTLGEK.....G.CRYYT. 11 PN-HRELEAWVGHPL.....NSLEEIIAAAQQLKAEGi....ENVIISMGAK.....G.SLWIN. 12 PN-ETEAERLTGIHI.....EQDDDAAKAAQILHDKGi....ATVIITLGSR.....G.VWLSE. 13 PN-LHELEDIVGRKL.....ETLEEIIEEGKKLNKKGi....EIVAISMGKE.....G.SVVIT. 14 PN-ESELALLSGLPT.....DTDEDIVRAARSLIARGi....RTVIVTLGAR.....G.ARMIT. 15 PN-ETEAEILTGVEV.....ADEQSAVKAASVFHDKGi....ETVMITLGAK.....G.VFVSR. 16 TN-ENEAEFITGIAQ.....NNVKDAEKAARAMLKMGp....QHAIITLGGK.....G.VLLAS. 17 IS-EEEIVFLTKG--.....EDPYDDNVVRKLFHPKL.....KLLLVTEGPE.....G.CRYYT. 18 PN-HHELGEMFGTAI.....TSVEEAVPYGKKLVEQGa....EHVIVSMAGD.....G.ALLFT. 19 PN-EVEAGQLVGFPV.....DGEDAARKAAGVLLQKGv....KSAIVKLGAK.....G.VVCAT. 20 PN-ETEAELLTGIEI.....KDIEDAKKAGDIFLGKGv....KFAIITLGEK.....G.AALIG. 21 FS-EEELQFLTGT--.....---QSIEEGLQAIADFQi....PLVVVTLGAK.....G.ALVVT. 22 PN-RRELEIWAGRPL.....PALGDVVEAAHALRDQGi....AHVVISLGAE.....G.ALWVN. 23 GT-REEFDMMEKLLN.....YEKSNDQVTAERWFSHHa....KIVVIKHGGD.....G.SIAYT. 24 PN-RDELASWYGSPL.....ATQQDIIRAATLLQRQGi....PHVVVSMGEE.....G.AIWLN. 25 GT-REEFDVLENR--.....TEKGDNDETIRYLFKHSp....ELIVIKHGVE.....G.SFAYT. 26 PN-KDELKEYAKREF.....KNNQEIIDYVRENLVDKa....EHVIISLGGE.....G.ALYID. 27 PN-DMEFELLLNKKF.....KNNTDIIDGAKEVIGLGv....SNVLISLGSK.....G.ALFVN. 28 PN-ETELEILTGMSV.....DTYDHIRLAARSLVDKGl....NNIIVTMSEK.....G.ALWMT. 29 VS-DDEVTFLTRG--.....-DAEKDDVVLSLMHDKL.....KLLIVTDGEK.....G.CRYYT. 30 GS-REEFDLMEGLIA.....KD-STDEETAKRWLDYGn....KIVVIKHGKD.....G.STAYT. 31 GT-RDEFDVMENR--.....-TGGSNEESVNHLFGHSa....DLVVIKHGVE.....G.SYAYS. 32 VS-ADELCQLSGA--.....---SHWQDARYYLRDLGc....DTTIISLGAD.....G.ALLIT. 33 PN-ETELEILTGMPV.....DTYDHIRAAARSLVDKGl....NNIIVTMGEK.....G.ALWMT. 34 LS-EDELVFLTGL--.....---AILEQGIDQFTARYqp...ALLLVTRGSQ.....G.VSVWQ. 35 PN-QKELSALVNREL.....TQPDDVRKAAQEIVNSGka...KRVVVSLGPQ.....G.ALGVD. 36 PN-QKELSALVNREL.....TQPDDVRKAAQEIVNSGka...KRVVVSLGPQ.....G.ALGVD. 37 PN-LSEFEAVVGKCK.....TEEEIVERGMKLIADYEl....SALLVTRSEQ.....G.MSLLQ. 38 PN-LSEFEAVVGKCK.....TEEEIVERGMKLIADYEl....SALLVTRSEQ.....G.MSLLQ. 39 VN-RNEAKNLTGY--.....---HDYRQAARHLKKLGp....KIVVIKLGAS.....G.SYILY. 40 PN-LSEFEAVAGKCK.....SEDELVERGMKLIADYDl....SALLVTRSEQ.....G.MTLLQ. 41 PN-LEELSQLLGKEMt....KDFEALKEVLQDELFEGi....EWIIVSLGAD.....G.VFAKH. 42 PN-LSEFEAVAGKCK.....SEDELVERGMKLIADYDl....SALLVTRSEQ.....G.MTLLQ. 43 PN-LSEFEAVAGKCK.....SEDELVERGMKLIADYDl....SALLVTRSEQ.....G.MTLLQ. 44 PN-HHELAELFGVKL.....DSVEDLIPYGKKCLELGa....QHVIVSMAGD.....G.ALLFT. 45 PN-LKELSALVNRDL.....TQPDDVRKAAQELVQSGka...RRVVVSLGPQ.....G.ALGID. 46 PN-LKELSALVNRDL.....TQPDDVRKAAQELVQSGka...RRVVVSLGPQ.....G.ALGID. 47 VS-DDEVAFLTQG--.....-DANDEKNVLSLWFDGL.....KLLIVTDGEK.....G.CRYFT. 48 GT-RDEFDMMENQIG.....G--NNEMTIDNLFKHKA.....EIIVIKHGVE.....G.SFAYT. 49 PN-ETELAFLSKSKI.....ETIEDIRKASKYLLDKGv....QNVITTIGEK.....G.SYFIN. 50 LS-DEEIKLLTEE--.....---EDLERGVEKLHSLGa....KIIAVTLGGK.....G.TLLSN. 51 MN-HVEAQLVANA--.....---GDHKSAVEKLARELkv...GELVVTLGPI.....G.AVAFK. 52 PN-HHELADLFGVKL.....GSVEELIPYGKKCLELGa....QHVIVSMAGD.....G.ALLFT. 53 GT-RDEFDMMENQVG.....----GKNEATKAYLFQHqa...KIVVIKHGVE.....G.SFAYT. 54 GT-EEEVLIASGE--.....---SDLLAALKTIRSLSk....ATIVLKRGPM.....G.CIVYD. 55 PN-RHELELWAGRPL.....PALQDVVDAARGIHARGv....AQVIVSLGEQ.....G.ALFVT. 56 FS-EEELLFLTDS--.....---DTLSDATAKLTQHYpd...KLIIVTLGKL.....G.ATYYL. 57 PN-NHELEAIFGTIL.....TSLDDVETYARRLLEMGa....QNVIISMAGD.....G.ALLVT. 58 PN-RHELEAWTGHPL.....GDHAALTAAAHALIARGi....QLVVISMGTE.....G.ALFVQ. 59 GT-EEEFHIAGGS--.....---TDTLTALNAVRKVSn....ATLVCKRGPM.....G.ASVFT. 60 CN-ESEAEILTGHAV.....SDPTTAGKAAMILLERGc....QVVVITLGAS.....G.CVILS. 61 PN-NHEIEEIFDVKI.....NSEKELIKYGKDLVSLGa....ENVIISMAGD.....G.ALLIT. 62 PN-THELSAALGREL.....GTQAELLAAARDLLGRGa....ELVAISQGED.....G.ALLVT. 63 CN-ESEAEILTGLTV.....GSAADAGEAALVLLKRGc....QVVIITLGAE.....G.CVVLS. 64 LS-EEELVFISSS--.....---NDLAYGIASVTERYqp...ELLLVTRGKA.....G.VLAAF. 65 AN-ETEFDLYGEALA.....LNGRDRAARMRDFAAKTg....RSIVVTLGGD.....G.VMAAT. 66 PN-NHELGAIFGVKL.....ESLDEIEKYARELLAKGa....QNVIISMAGD.....G.ALLVT. 67 PN-NHELGAIFGVKL.....ESLDEIEKYARELLAKGa....QNVIISMAGD.....G.ALLVT. 68 PN-TEELSQIMEREIt....NDVAVLKHALASPIFSGi....DWIIVSLGSQ.....G.AFAKH. 69 PN-REELEAIFETSF.....KNNEQIIPYGQKLLEMGa....QNVIVSMAGD.....G.ALLFT. 70 PN-NHELEAIFGTIL.....TSLDDVETYARRLLEMGa....QNVIISMAGD.....G.ALLVT. 71 PN-QKELSALVNREL.....TQPDDVRKAAQEIVNSGka...KRVVVSLGPQ.....G.ALGVD. 72 FS-EEELLFLTDS--.....---TSMAQGLQQIAAMNi....ALVLVTQGAK.....G.VWRVF. 73 PN-LEELSQLLGKEMt....KDFDALKEVLQDELFDGi....EWIIVSLGAD.....G.VFAKH. 74 PN-RRELEIWAGRKL.....PEMKDVIEAAHALREQGi....AHVVISLGAE.....G.ALWVN. 75 PN-QTEAFELTGVEV.....HDFDGAAHAAGKLLDLGp....KAALITLGAQ.....G.AYYAD. 76 PN-ETEAAEITGIEP.....TDLASAEAAGRKLLERGp....KIVILKLGSR.....G.ALLVT. 77 GN-ETEAATFAREQG.....FETKDIKEIARKTQALPkv7rqRTVIFTQGRD.....D.TIVAT. 78 PN-NHELEAIFKVNL.....NGITDVEKYARQILAKGa....QNVIISMAGD.....G.ALLVT. 79 PN-ETEAALLTARRV.....DSPEAALNAAADLHAQGa....RHVIVTLGAR.....G.VAYVD. 80 LS-DKDLEYIFQ---.....---EDLETAVDKIPIKEn....GLLFVTMGER.....G.CLVKF. 81 PN-IYELEDLFNAKF.....DSTKELIKIGKNLVESGv....QNIIISMGSD.....G.AIFIG. 82 PN-KDELEMLTGSSI.....IGENDIIEHVKVLNKRGi....KCVIISLGAS.....G.SLVGF. 83 PN-KDELEVMFNTTV.....NSDTDVIKYGRLLVDKGa....QSVIVSLGGD.....G.AIYID. 84 GN-ETEAATFAREQG.....FETKDIKEIAKKAQALPkv7rqRTVIFTQGRD.....D.TIVAA. 85 GN-ETEAATFAREQG.....FETKDIKEIAKKAQALPkv7rqRTVIFTQGRD.....D.TIVAA. 86 PN-EHECKELFPN--.....-------LALEEILKKYs....NRLIVTLGSE.....G.VIFHD. 87 PN-EKEIEALSKDFF.....GEFLTVEKAAEKFLELGv....KNVIVKLGDK.....G.VLLVN. 88 PN-KEELESITEIKI.....LDDEDMKKAVKYLRDKGi....KNVIVTLGER.....G.VYVSS. 89 GT-EEEFHIAGGS--.....---TDTLEALKAVRRVTk....AALVCKRGPM.....G.AVVFE. 90 PN-LEELSQLLGKEMt....KDFKALKAVLQDELFEGi....EWIIVSLGAD.....G.VFAKH. 91 PN-ETEASFLSGVTI.....TDINDAKKAGNIILQSGv....KKVIITLGAR.....G.SLICE. 92 PN-NEELSQLLGKEVt....KDIEELKDVLKESLFSGi....EWIVVSLGRN.....G.AFAKH. 93 PN-ETELSRLTGMPT.....ETFEQISQAVAKCHKLGv....KQVLVKLGSK.....GsALFIQ. 94 PN-ETELSRLTGMPT.....ETFEQISQAVAKCHKLGv....KQVLVKLGSK.....GsALFIQ. 95 GN-ETEAATFAREQG.....FETKDIKEIAKKAQALAkv7rpRTVVFTQGRD.....D.TVVAT. 96 PN-HHELGELFGVEI.....STAEDILPYGRKLIEQGv....EHVIVSMAGD.....G.ALLFT. 97 PN-ETETEELTGLKV.....SSVDEARTASGKLLEKGv....GTVIVTLGDK.....G.ALLHS. 98 AS-VRELRECVGSEL.....LTEPEQLAAAHELIDRGra...EVVVVSLGSQ.....G.ALLAT. 99 PN-LFEFEKIVGKCY.....RENEILQRGIKLLSELQl....SALLVTRSKN.....G.MTLFQ. 100 LS-REELDYLAGTL-.....--DSDASAVTQKLWQGHa....RWLLVTDGGG.....P.VHWQT. 101 PN-DEELSQWCGREL.....TTLTDCQQAAAELAQKQi....ENIVISMGAE.....G.VMWLH. 102 MN-EEEAAKISGMLF.....GTTYACRTLCRLLTDRYpki..SVICITKGPE.....G.AAVYQ. 103 GN-ETEAATFAREQG.....FETKDIKEIAKKAQALAkv7rpRTVVFTQGRD.....D.TVVAT. 104 PN-KDELEVMFNTTV.....NSDTDVIKYGRLLVDKGa....QSVIVSLGGD.....G.AIYID. 105 PN-DDELAGNLGLDV.....SNHQQVREAMRTLHQLGa....RNVLLTMGAE.....L.PYFSD. 106 PN-RHELEAWTGHPL.....GDHAALTAAAHALIARGi....QLVVISMGTE.....G.ALFVQ. 107 PN-NEELSQLLGREVs....EDLDELKEVLQEPLFAGi....EWIIVSLGAN.....G.TFAKH. 108 PN-HHELSELVSKPI.....ASIEDAIPHVQRLIGEGi....ESILVSFAGD.....G.ALFAS. 109 PN-LAELNELFETNYqf...NQKTEIVTLGKKLQEKGa....QNVLISSGKD.....G.SILIT. 110 GN-ETEAATFAREQG.....FETKDIKEIARKTQALPkv7rqRTVIFTQGRD.....D.TIVAT. 111 PN-ISELYQLLNQPLd....ESLESLKQAVSQPLFEGi....EWIIVSLGAQ.....G.AFAKH. 112 AN-RHEIKRVSEMTG.....KSFSELRAMI-------.....EVIVITYDAE.....G.SRIYT. 113 PN-SDELAELTGS--.....---HEPQRAAQAARRRGa....RSVIASLGPE.....G.LLAVT. 114 IS-EEELAFITGE--.....---QTIEAGLDQLVAYNi....PLVFVTLGEK.....G.SIVSY. 115 PN-ISELYQLLNQPLd....ESLESLKQAVSQPLFEGi....EWIIVSLGAQ.....G.AFAKH. 116 PN-NEELSQLLGREVs....EDLDELKEVLQEPLFAGi....EWIIVSLGAN.....G.TFAKH. 117 PN-IDELSDLLGVKVk....DSIEDLKLILNTPMFNGi....EWIVISMGAK.....G.SFAKH. 118 PN-LSEFEQIVGKCH.....QEKQILQRGIKLVSELNl....SALLVTRSKN.....G.MTLFQ. 119 MN-EDEFKAKYGS--.....---------LDRIKDVKa....RIAIATLNGG.....G.ALVRD. 120 PDLRGNHASFLGVDL.....KTFDDYVKLAEKLAEKS.....QVSVVSYEVK.....N.DIVAT. 121 AS-EEEVDYLEDNGI.....EVEGKLI----------.....--TAITMGSK.....G.AKL--. 122 VN-DNEAGAVLDD--.....-------DGGPTAPDSD.....RVVVVKHGSE.....G.ATVHT. 123 PN-LSEFEAVAGKCK.....SEDELVERGMKLIADYDl....SALLVTRSEQ.....E.MTLLQ. 124 LS-EEELAFISGS--.....---DDIVSGIARLNARFqp...TLLLVTQGKA.....G.VQAAL. 125 PN-EDEVIAILDE--.....-KTNSLEENIRTLAEKI.....PYLVVSLGAK.....G.SICAH. 126 PN-AEELAEAVGRPL.....ATVGDAVKAAEELRELGa....RSVLASLGAD.....G.QLLVD. 127 GN-ETEAATFAREQG.....FETKDIKEIARKTQALPkv7rqRTVIFTQGRD.....D.TIVAT. 128 PN-EHEASILFPE--.....------LTISEALALYP.....AKLFITEGKQ.....G.VRYSA. 129 GN-HHEIDRICSKLS.....VD-------IHGLREMGp....GVVVKTYGKE.....G.SIIYS. 130 PN-RHEAEILAGFPI.....TDTDDLIKASNYFLGLGi....KKVFISLDAD.....G.IFYND. 131 VN-EHEAKVILGDSL.....VG-ERPEDWARVLLAKGp....RSVVVTLGAE.....G.ALVAS. 132 PN-EDEVIAILDE--.....-KTNSLEENVRKLAEKI.....PYLVVSLGAK.....G.SICAH. 133 AN-RQEALALYET--.....---EDFDRALELLARDC.....KLAAVTLSEE.....G.SVVVR. 134 GT-EEEFLIAGGVP-.....---RDLMASLRAVRQISg....AVLVVKRGAL.....G.CCVIE. 135 PN-VEELADLCSAPM.....DDLVAQRQAAERLRHDGv....GQVVISQGAA.....G.VNWFA. 136 PG-INEGLVLMGS--.....---DKPEEIADFYLNKGv....KLVIIKLGSK.....G.AYVKT. 137 AN-KHEIKRVSEMTG.....KSFSELRDMI-------.....DVIVVTYDAE.....G.SIIYR. 138 CT-DEEAVWLFGH--.....---QDPVTIHQKLPHLQ.....-GVLVTAGDK.....G.CSYSL. 139 PN-MSEFEAVVGKCN.....TEEEIIKKGLKLISDIEl....TALLVTRSEK.....G.MTLLR. 140 PN-RLEAETLSGIAL.....SGREDVAKVAAWFHQHGl....NRLVLSMGGD.....G.VYYSD. 141 LS-DEELKIISGE--.....---KNIKNGVKLLASNN.....KVIAVTLGKE.....G.TMISN. 142 VN-EHEGALVLDMLGtp...ATTSDPQSLVTELLEQGf....TSVVMTLGAE.....G.ALVGT. 143 FS-EPGLARLTGM--.....---SEAIDALKKAQMLTn....GHVYVTRGSE.....G.CNWLE. 144 MN-EEEAEAISGMLF.....DTIYKFRTLCRLLTDRYpem..SVICITKGPD.....G.AAVYH. 145 AN-EHEAGLILDQFGag...IDSMDPHELAQALLDAGf....ASVVLTLGSA.....G.ALVAD. 146 FS-EPGLARLTGV--.....---KEMASALKQAQTLTn....GHVYVTQGSA.....G.CDWLE. 147 LT-SEEVEALTGI--.....---RNPVKAGQEILRNGkgt..KWVIVKMGPK.....G.SILVT. 148 VS-DEELEIISGV--.....---KDHEKGVAILHEIGa....NIVAVTLGKS.....G.TLLSN. 149 AN-EEDIEKVLGISVeg9gkLNREAYAKIAEEVTRKYnf...KTVGITLRESis7nyW.SVMVF. 150 FS-EPGLARLTGV--.....---KEMASALKQAQTLTn....GHVYVTQGSA.....G.CDWLE. 151 FS-EPGLARLTGV--.....---KEMASALKQAQTLTn....GHVYVTQGSA.....G.CDWLE. 152 PN-EHEASILFPE--.....------LTISEALALYP.....AKLFITEGKQ.....G.VRYSA. 153 AS-EEEVLYLENQGV.....E-------------VKGs....MLTAITLGPK.....G.CRLIK. 154 VS-QEEAIMLSKE--.....---SDLQQSALKLLNHGa....KAVAITLGKD.....G.TLLAT. 155 MN-KHEFERASNLLN.....FEIDDYLERV-------.....DALIVTKGSK.....G.SVIYT. 156 FS-DEDLAWFGLE--.....---GDEDTLARHWLHHGa....KLVVVTRGAK.....G.AVGYS. 157 FS-DEDLAWFGME--.....---GSHDALAAEWLKRGp....KLVLITRGAD.....G.AVGYT. 158 FS-DEDLAWFGLE--.....---GDEDTLARHWLHHGa....KLVVVTRGAK.....G.AVGYS. 159 PN-RLEAETLSGIAL.....SGREDVAKVAAWFHQHGl....NRLVLSMGGD.....G.VYYSD. 160 PN-VAELGAHLGRTL.....TGLESVREAARDLAASGv....GLVAVSMGAG.....G.AVLVR. 161 PN-ENECLQLFGDE-.....----P-------DANLR.....QKLIMTKGAD.....G.VQFYE. 162 PN-MSEFEAVVGKCN.....TEEEIIEKGLKLISDIEl....TALLVTRSEK.....G.MTLLR. 163 PN-DEEVKAIFGLTV.....SDDNDAKNTLTTLHALGa....QNVLLTLGAK.....G.MYFSN. 164 VN-DYESNLLQERTG.....WDEKDIVSRV-------.....QAYITTQGPK.....G.ALVHT. 165 PN-DEEVKAIFGLTV.....SDDNDAKNTLTTLHALGa....QNVLLTLGAK.....G.MYFSN. 166 PN-EIEFKELVNT--.....---DDFEYGLNLLLKKVk....KAVIVTLGER.....G.ALLAT. 167 LS-DEEFNLLKEYGL.....EPRGKLITA--------.....----ITYGAE.....G.CRIES. 168 MN-EDEFKRKYGS--.....---------LEKITELKs....RIAIATLNGG.....G.ALVRD. 169 IN-ELEAGEFSGLEIrl6gePHIAHIAAAARELLDAGv....RQRVVIHYPE.....G.AWGET. 170 PG-RDEAAFLFDT--.....---DELAQMFSRLLTGRt....TSVVIKDGAK.....G.AHFME. 171 PT-LPELEILWGQAI.....TSDADRNTAVNALHQQGv....QQLFVYLPDE.....S.VYCSE. 172 AN-EDEAKALYKT--.....---KSLETAIAAMRMDC.....RLSVITRSEK.....G.AVVVT. 173 PN-FAEAKLLTGK--.....---ETLDEIADCFLACGv....KTVVIKTGKD.....G.CFIKR. 174 GT-EEEIMIASGA--.....---DDCLSALKTIRALSa....ATIVLKRGAM.....G.CIVYD. 175 PN-FAEAKLLTGK--.....---ETLDEIADCFLACGv....KTVVIKTGKD.....G.CFIKR. 176 GT-EEEFHIAGGS--.....---TNTLDALRGVREVSd....AALVCKRGAL.....G.CSVYT. 177 PT-LPELEILWGQAI.....TSDADRNAAVNALHQQGv....QQLFVYLPDE.....S.VYCSE. 178 PN-MSEFEAVVGKCD.....SEEEIIEKGLKLIEQIDl....SALLVTRSEK.....G.MTLLR. 179 AN-SDEARAFCHF--.....SAEESPISATRYMSHFV.....PFVSVTDGIN.....G.SYIGV. 180 AN-SDEARAFCHF--.....SAEESPISATRYMSHFV.....PFVSVTDGIN.....G.SYIGV. 181 PT-LPELEILWGQAI.....TSDADRNTAVNALHQQGv....QQLFVYLPDE.....S.VYCSE. 182 AN-SDEARAFCHF--.....SAEESPISATRYMSHFV.....PFVSVTDGIN.....G.SYIGV. 183 CS-TNFPQEWTGAP-.....---SSPSALLSMLIRLPkl...KFVIMTLGEH.....G.CVMLE. 184 PN-QKELSALVNREL.....TQPDDVRKAAQEIVNSGka...KRVVVSLGPQ.....G.ALGVD. 185 AN-AAEVCALFET--.....---DDFDAAVKALAERC.....EIAAVTRSEK.....G.SVVAA. 186 PG-LDEARAICGL--.....---EKRADVIAFFLNRGv....GHTVFKMGAE.....G.SSIAS. 187 FS-DEDLDWFGLQ--.....---GDHDALAAHWLNHGa....KLVVITKGAE.....G.ASGYT. 188 MN-EDEFKRKYGD--.....---------LKNITKVKs....RIAIATLNGG.....G.ALVRD. 189 PN-RKELGEAVGHAV.....FADDEIVAAARELISAHgf...DFVVATRSEK.....G.MSVVG. 190 PN-LAELAALVGREVa....DSPAAIREAALELHALGa....ELVWVRRGER.....G.SVLSL. 191 LA-KEEAEWLFDT--.....---SDP---GAITYRLGsi...EGVLVTDGEN.....G.CGYCL. 192 PN-RKEAAEATGIVE.....TSDAASEDAGAAILAMApgl..QAALITRGGA.....G.MTLAV. 193 PN-EHECRIVL----.....---DDFTSPIEDLLAKYp....NKLLMTEGSN.....G.VRFHN. 194 PN-RDELAAWTGRPL.....NDRGALSAAAHELIARGi....QLVVISMGTE.....G.ALFVQ. 195 VN-RRELEILTGSP-.....-------DPAMASAELGv....DVVVMKMGSE.....G.VRAFD. 196 GN-EEDAEMHFGIKPe11hnVKAEAFLSVCQQMMKKFpka..KKVITTLRGSis8twA.GVLYD. 197 -N-YAEAKLLTGK--.....---ETLDEIADSFLACGv....KTVVIKTGKD.....G.CFIKR. 198 GN-EEEFAHLAKVHNl15keHAVEVCTGALRLLTAGQntgatKLVVMTRGHN.....P.VIAAE. 199 PN-QDELIAMANALCa18ieDMFRALKPAILVLLKNGv....KVVIVTLGSN.....G.ALLCS. 200 LN-QHELLALTGT--.....---RSLSAGLARLAEAGv....ERVAVKVGKM.....G.SVVWT. 201 PN-QDELIAMANALCa18ieDMFRALKPAILVLLKNGv....KVVIVTLGSN.....G.ALLCS. 202 GN-EEEFAHLAKVHNl15keHAVEVCTGALRLLTAGQntgatKLVVMTRGHN.....P.VIAAE. 203 GN-EEEFAHLAKVHNl15keHAVEVCTGALRLLTAGQntgatKLVVMTRGHN.....P.VIAAE. 204 VS-DEDLRGLFPE--.....--LDETSALAQLRAWAPt....AAILMTRGAA.....G.MTLIT. 205 GN-EEEFAHLAKVHNl15keHAVEVCTGALRLLTAGQntgatKLVVMTRGHN.....P.VIAAE. 206 VS-DEDLHLLYPG--.....---QSPESVLQGWLQHRc....QLVFLTRGGD.....G.ASVFS. 207 PG-LDEARAICGL--.....---EKRADVIAFFLNRGv....GHTVFKMGAE.....G.SSIAS. 208 IG-DGELEYLNKN--.....---------GIALEDFNf....ALVAITRGAE.....G.STIIH. 209 VS--KDVAKHLGF--.....---QSAEEALRGLYGRVrkg..AVLVCAWAEE.....G.ADALG. 210 PN-EKELREMSKFE-.....---GSVEELGKKLKEELel...ETLIVTRGEK.....G.MSLFT. 211 VS--KDVAKHLGF--.....---QSAEEALRGLYGRVrkg..AVLVCAWAEE.....G.ADALG. 212 IN-DIEAKWLTNSEAfa...SSKTVLQRMAEQMMVLGv....RDTVIIHEPK.....W.AVAMN. 213 CP-ENFPQTWTEVS-.....---STPGALVSMLLRLPkl...KFVIVTSGEH.....G.CLMVQ. 214 AS-EEDLALLYPG--.....---RDPGEVARGWLNPRc....RLVFVTHGGA.....G.ASVHC. 215 PN-LSELAASLGIPVa....NDDREVEQACLLLGEKLtv...ESLVVTRSEK.....G.MTVYD. 216 VS--KDVAKHLGF--.....---QSAEEALRGLYGRVrkg..AVLVCAWAEE.....G.ADALG. 217 VN-DYESNLLQERTG.....WNEQDIVSRV-------.....QAYITTQGPK.....G.ALVHT. 218 CP-ENFPQTWTEVS-.....---STPGALVSMLLRLPkl...KFVIVTSGEH.....G.CLMVQ. 219 PN-NHELEAIFGTIL.....TSLDDVETYARRLLEMGa....QNVIISMAGD.....G.ALLVT. 220 IN-ELEAGELSGLEMrl6gtPDVHHIAQAAKQLLEAGv....RQRVVIHCPE.....G.AWGVE. 221 FS-RSDASD------.....---DEVKRVLDTAVSAGv....ELVTVTQGAR.....G.ATVCH. 222 VN-AGEAEQLTGT--.....---GDAASAARELIRQGt....EGTIVTLGAA.....G.CLVAD. 223 AN-EDEAAELLRG--.....EQEAGPEAALEFLGRHC.....RWAVVTLGSK.....G.CIAKH. 224 PN-IDEFQTMINTFF.....HDQQSLIAAIKKFH-YC.....KLLLLSDGDK.....G.AYLFD. 225 MN-EKDAMFVLGMKT.....EETEREEQLVDLIPQVAe....TYHIATIAGT.....H.RSINS. 226 VN-EIEGLQIVESVFd14kdDFLGEYRKICELLYEKLmn6krGIVVMTLGSR.....G.VLFCS. 227 GS-IEEAELAIGE--.....GDGDDCNTVLKKLVEKFql...KYATIILRNRft8dwT.AVLYD. 228 VN-EIEGLQIVESVFd14kdDFLGEYRKICELLYEKLmn6krGIVVMTLGSR.....G.VLFCS. 229 PN-GLELGQLANTDGee9aqGDYDAIIAAADVLVNRGi....EQVLVTLGAA.....G.AVLVN. 230 AN-QEAAANLTDMEEv....LTPDQARKAAETLIAKGa....KSVIITMGEQ.....G.AVYMS. 231 FS-DEDLAFFFPG--.....---ASEAQALQELRGLNpr...CPIVVTRGAA.....G.ASLYH. 232 PN-RQEIEMLFS---.....---EDYRTAAERCIEMGi....EIVAVKLGSE.....G.CWIKK. 233 MS-ADEFSLLGVE--.....---------TADVLRFV.....DYLIVTQGKL.....G.SACYT. 234 LS-DEDLHWFGEA--.....---GSHEDVIRNWLDRGp....KLIVVTHGSE.....G.AVGYT. 235 ---VDGLSIAFGSAG.....EDETSAERLTGEFLARGa....RLAVVTRGAL.....G.SLASD. 236 GN-RQEFEALAEA-A.....GGFRNVDELADHLLQSGgt...KVIFVTNGSA.....G.VQVIT. 237 FS--KELAGQLGWK-.....TPRQSCEELASKIPEGGpk...PVFICPWGSA.....G.AGAMD. 238 FS-GSDLSE------.....---SECGELAKTAHGYGa....KMVCMTRGGQ.....G.AILSA. 239 AN-EDEARELLGGEL.....T--FDPEEALAFLAKYC.....KWAVVTLASK.....G.CIAKH. 240 LN-ERESTK------.....---------VKIESLK-a....RLIVIKMGSK.....G.AKVIS. 241 CS-REEAEILSDMSI.....VTVDDALRVAEVLAMKGa....PLTIVTMSEL.....G.AVYVDl 242 LN-DDELEILTGS--.....-----RKSGISRLLGVGv....DYVVVTHGPG.....G.ASFFS. 243 VG-LDEAQTLWKS--.....----CTAGAVRDHLPSP.....DVVVVKDGGR.....E.AVAFR. 244 GN-ERECSFRKCD--.....-----------------.....---VVKMGSK.....G.ARW--. 245 PN-RDEFVAMVNANN.....SN-VDQQELVQLIKQFQtt...QNLLMSDGAQ.....G.AYFFD. 246 PN-IDEFQTMINTFF.....HDQQSLIAAIKKFH-YC.....KLLLLSDGDK.....G.AYLFD. 247 ---------------n16ieDMFRALKPAILVLLKNGv....KVVIVTLGSN.....G.ALLCS. 240 250 260 270 2 | | | | 1 R.....EG.....VWLIRS.....KEEIDTSHLLGAGDAYVAGMVYYF.....IKHGAN.....F 2 Q.....EF.....KGRVGG.....-VKVKPVDTTGAGDAFVSGLLNSL.....-ASDLTll7kkL 3 K.....EF.....KGRVNS.....-IKVKAVDTTGAGDAFTGGVLKCL.....-ASDASly7krL 4 R.....DF.....RGAVPS.....-YKVQQVDTTGAGDAFVGALLRRI.....-VQDPSsl7kkL 5 A.....SG.....EWIAKP.....-PAVDVVSTVGAGDSMVGGLIYGL.....-LMRES.....S 6 K.....KF.....HGSVET.....-FHVDAVDTTGAGDSFVGALLQQI.....-VDDQSvl7arL 7 E.....GR.....VEHFPV.....-ARVKALDTTAAGDTFVGGFAAAL.....-ARGLD.....E 8 A.....SG.....EWIAKP.....-PSVDVVSTVGAGDSMVGGLIYGL.....-LMRES.....S 9 K.....TF.....KGAVDP.....-FHVNAVDTTGAGDSFVGALLNQI.....-VDDRSvl7erL 10 K.....TF.....KGAVDP.....-FHVNAVDTTGAGDSFVGALLNQI.....-VDDRSvl7erL 11 N.....EG.....VLKAEP.....AQCENVVSTVGAGDSMVAGLIYGF.....-EKGLS.....K 12 Q.....GK.....GKLVAG.....-FKVNAVDTIAAGDTFNGALLTAL.....-LEGQS.....M 13 D.....DA.....VFRVKP.....-LKVEVKGTVGAGDAYVAGFAHGI.....-YRGLS.....L 14 S.....DE.....IVNIEP.....-VKVTPRDTTGAGDAFIGSFARFY.....-AETRE.....V 15 K.....GK.....SRIIKG.....-FCVQAIDTTAAGDTFNGGFVTAL.....-LEEKS.....F 16 Kgv...DD.....VEHTAV.....-IKVDAVDTTGAGDCFCGSLAAHL.....-VAGHP.....I 17 K.....DF.....SGRVHG.....-LKVDVVDTTGAGDAFVAGILSQL.....-ANDLSll7erL 18 N.....EA.....VYFANV.....-PKGKLVNSVGAGDSVVAGFLAGI.....-SKQLP.....L 19 N.....KE.....TFFVPA.....-FSVDTLDTVAAGDAFNGGLATAL.....-YSGLS.....L 20 K.....DF.....CEIVPA.....-YRVNAIDTTAAGDSFIGGLSSKLdtk..NLGKET.....L 21 P.....NS.....RQIVSG.....-KAVKPIDTTGAGDAFVGGLLYRLsvaqdWHNQAT.....I 22 A.....SG.....AWLAKP.....-PACDVVSTVGAGDSMVGGLIYGL.....-LMRES.....S 23 R.....DG.....QSHRGG.....IFKTKVLKTFGAGDSYASAFIYGL.....-MQGLE.....I 24 E.....NT.....VLHAQP.....PQDTPIVSTVGAGDTMVAGLIYGM.....-LNAYS.....A 25 K.....AG.....EAYRGY.....AYKTKVLKTFGAGDSYASAFLYAL.....-ISGKG.....I 26 K.....NF.....SFFAQPl....RVKENVVNTVGAGDSVVAGFISCI.....-LKHNE.....V 27 K.....DK.....SYYAKG.....-LVVPVKSTVGAGDSMVAAFVYGI.....-INSLN.....E 28 R.....DQ.....EVHVPA.....-FKVNAVDTSGAGDAFIGCFSHYY.....-VQSGD.....V 29 K.....KF.....KGRVPG.....-YAVKAVDTTGAGDSFVGAFLVSLgk6siLDDEG-k....L 30 R.....DG.....KAYRIK.....PFPVKLLKSFGGGDAYASAFIYGI.....-LEGWD.....M 31 K.....SG.....EVFRAQ.....AYKTKVLKTFGAGDSYASAFIYGL.....-VSGKD.....I 32 A.....EG.....EFHFPA.....-PRVDVVDTTGAGDAFVGGLLFTLsran.CWDHAL.....L 33 R.....DQ.....EVHVPA.....-FRVNAVDTSGAGDAFIGCFAHYY.....-VQSGD.....V 34 A.....GR.....LQHFAA.....-PQVEVTDTTGAGDAFVAGLLAAL.....-VQETNpl6qrL 35 S.....EN.....CIQVVP.....-PPVKSQSTVGAGDSMVGAMTLKL.....-AENAS.....L 36 S.....EN.....CIQVVP.....-PPVKSQSTVGAGDSMVGAMTLKL.....-AENAS.....L 37 P.....GK.....APLHMP.....TQAQEVYDVTGAGDTVIGVLAATL.....-AAGNS.....L 38 P.....GK.....APLHMP.....TQAQEVYDVTGAGDTVIGVLAATL.....-AAGNS.....L 39 S.....DG.....EVFVPA.....IKPERVVDTTGAGDSYAAGFIAGL.....-LRGYT.....I 40 P.....NK.....APLHMP.....TQAQEVYDVTGAGDTVIGVLAATL.....-AAGNT.....L 41 N.....DT.....FYNVDI.....-PKIEIVSAVGSGDSTVAGIASGL.....-ANDED.....D 42 P.....NK.....APLHMP.....TQAQEVYDVTGAGDTVIGVLAATL.....-AAGNT.....L 43 P.....NK.....APLHMP.....TQAQEVYDVTGAGDTVIGVLAATL.....-AAGNT.....L 44 G.....ED.....VYFADA.....-LKGELKNSVGAGDSMIAGFVGTF.....-DKTKD.....P 45 S.....EN.....CIQVVP.....-PPVKSQSTVGAGDSMVGAMTLKL.....-AQDAS.....L 46 S.....EN.....CIQVVP.....-PPVKSQSTVGAGDSMVGAMTLKL.....-AQDAS.....L 47 K.....DF.....KGSVPG.....-FSVNTVDTTGAGDAFVGSLLVNVak6siFHNEEK.....L 48 K.....AG.....ETFRAQ.....AYKTKVLKTFGAGDSYASAFLYGL.....-FSGEN.....I 49 K.....NT.....EKLFDA.....-IKVTAVDTTAAGDSFTGALAFAL.....-SKGEK.....I 50 G.....IH.....SEIVPS.....-IKINQVDSTGAGDAFVGAVLKKVse7kkNLDLNS.....W 51 N.....GR.....LLHVDA.....-FKVNAVDTTGAGDCFAAAYITMY.....-LRGRD.....L 52 G.....ED.....VYFADA.....-LKGELKNSVGAGDSMIAGFVGTF.....-DKTRD.....P 53 K.....AG.....ETFQAQ.....AYKTKVLKTFGAGDSYASAFLYGL.....-FSDES.....I 54 Gpi6dlED.....GIVGKG.....-FPIEVYNVLGAGDAFMSGFLRGW.....-LTGEP.....H 55 G.....EG.....IWQASL.....-PPVRAASTVGAGDAMVAGVLAGW.....-HAGAS.....T 56 Q.....GK.....SQLVSS.....KKALIPVDTTGAGDAFVSGLLFGIsqvknWQNPTA.....L 57 K.....EA.....TYFAKP.....-IKGEVKNSVGAGDSMVAGFTGEF.....-MKSQN.....P 58 R.....DQ.....QLIARP.....-PRLAQGSSVGAGDAMVAGLAAAL.....LDDATE.....L 59 Gdi6slDD.....GETGEG.....-FPIEVFNVLGAGDGFMAGLFRGW.....-LRGED.....W 60 Qa....EP.....VPKHIP.....TEAVKAVDTTGAGDSFVGALAFYLa....YYPNLS.....L 61 K.....DG.....VFKGNA.....-PKGEVKNSVGAGDSLVGGFLAKY.....-VETKD.....L 62 P.....GA.....TVQAKP.....-PHVQVVSTVGAGDAMVAGLVSAH.....-LDSLP.....L 63 Qt....EP.....EPKHIP.....TEKVKAVDTTGAGDSFVGALAFYLa....YYPNLS.....L 64 Q.....QK.....FTHFNA.....-RPVASVDTTGAGDAFVAGLLASL.....AANGMPtdmtaL 65 P.....SD.....FLTVAA.....-MKITPVDTVGAGDTFCGYFAAGL.....-SSGLA.....L 66 S.....EG.....AYFAKP.....-IKGTVKNSVGAGDSMVAGFTGEF.....-VKSKD.....A 67 S.....EG.....AYFAKP.....-IKGTVKNSVGAGDSMVAGFTGEF.....-VKSKD.....V 68 G.....QT.....FYKVTI.....-PKIAVVNPVGSGDSTVAGITSAL.....-AAGAS.....D 69 N.....EK.....VYFAQG.....-IKGELKNSIGAGDSTVAGFLAEY.....-SQSKD.....P 70 K.....EA.....TYFAKP.....-IKGEVKNSVGAGDSMVAGFTGEF.....-MKSQN.....P 71 S.....EN.....CIQVVP.....-PPVKSQSTVGAGDSMVGAMTLKL.....-AENAS.....L 72 E.....SQ.....SELITG.....-QVVSPIDTTGAGDAFVGGLLACL.....-SRHADwk6pvV 73 K.....DT.....FYNVDI.....-PKIKIVSAVGSGDSTVAGIASGL.....-ANDED.....D 74 A.....SG.....EWIAKP.....-PSVDVVSTVGAGDSMVGGLIYGL.....-LMRES.....S 75 A.....SA.....TFALRA.....-FPVKVVDTTAAGDAFNGAFAASL.....-AHRLP.....I 76 A.....DE.....VKHFTP.....-FKVKVVDTVAAGDSFNGGFAVAF.....-SQARP.....L 77 G.....ND.....VTAFPVld...QNQEEIVDTNGAGDAFVGGFLSQL.....-VSNKP.....L 78 S.....DA.....TYFAKP.....-IKGQVRNSVGAGDSMVAGFTGEF.....-VKSAN.....P 79 A.....TT.....RLLMPA.....-HPAQAIDTTAAGDTFVGALATAL.....-AEGAA.....P 80 K.....GE.....KRMVPS.....-FKVKPVDATGCGDSFTAAVIHKY.....-LEKTPetiedA 81 G.....KN.....VAFRAF.....VPKINFVSTIGAGDSVIAGFVYAF.....-DNGST.....L 82 D.....GE.....LFKVTI.....-PKVKAINPVGSGDSLVGGFAVGF.....-ERNYN.....I 83 K.....EI.....SIKAVN.....-PQGKVVNTVGSGDSTVAGMVAGI.....-ASGLT.....I 84 E.....ND.....VTAFPVld...QNQEEIIDTNGAGDAFVGGFLSQL.....-VSDKP.....L 85 E.....ND.....VTAFPVld...QNQEEIIDTNGAGDAFVGGFLSQL.....-VSDKP.....L 86 G.....ET.....LQKIPA.....-IKAKVVDTTGAGDTFNGAFAFGL.....-TENLS.....I 87 K.....NE.....KKHFPT.....-FKVKAVDTTAAGDVFNGAFAVAL.....-SEGKN.....P 88 E.....EL.....EKFIEP.....-YQTEIVDATGAGDALTAGLVYGI.....-FNGYS.....L 89 Gdi6dlDK.....GQSGQG.....-FPIEVFNVLGAGDGFMSGLLRGW.....-LKGED.....W 90 K.....DT.....FYNVDI.....-PKIKIVSAVGSGDSTVAGIASGL.....-ANDED.....D 91 H.....AR.....TLYIPA.....-WSAVVKDAAGAGDAFNGALAAAL.....-ARQAD.....M 92 G.....DV.....FYKVDI.....-PDIPVVNPVGSGDSTVAGIASAL.....-NSKKS.....D 93 G.....EK.....PIQQSI.....IPAAQVVDTTGAGDTFTAAFAVAM.....-VEGKS.....H 94 G.....EK.....PIQQSI.....IPAAQVVDTTGAGDTFTAAFAVAM.....-VEGKS.....H 95 E.....NE.....VMAFAVld...QNQKEIIDTNGAGDAFVGGFLSQL.....-VYNKP.....L 96 A.....EG.....IYEATV.....-PKGVVINSVGAGDSLVAGFVGKY.....-EQTKD.....I 97 K.....GR.....SEHVPA.....ISAGPVVETTGAGDAFNGGFAAAL.....-SRGVE.....P 98 R.....HA.....SHRFSS.....-IPMTAVSGVGAGDAMVAAITVGL.....-SRGWS.....L 99 K.....EK.....KPIHFP.....AASKIASDVTGAGDTVIAIIAASL.....-ATGYS.....L 100 R.....VD.....SGQVPA.....-FHVQVRDSTAAGDAFVGGLLFQLaa6st------l10aaI 101 E.....NQ.....WLHAKP.....-PKMQVVSTVGAGDTLVAGLCWGH.....-MQRME.....K 102 D.....GV.....YEEIKT.....-TPVEVADTVGAGDAFSAGFLYTF.....-LSGYG.....V 103 E.....NE.....VMAFAVld...QNQKEIIDTNGAGDAFVGGFLSQL.....-VYNKP.....L 104 K.....EI.....SIKAVN.....-PQGKVVNTVGSGDSTVAGMVAGI.....-ASGLT.....I 105 G.....EG.....VWFCSA.....-RKIALVSSACAGDAALGAFLSKW.....-LNKED.....V 106 R.....DQ.....QLIARP.....-PRLAQGSSVGAGDAMVAGLAAAL.....LDDATE.....L 107 G.....DT.....FYKVDI.....-PRIQVVNPVGSGDSTVAGISSGL.....-LHKES.....D 108 A.....EG.....MFHVNV.....-PSGEVRNSVGAGDSVVAGFLAAL.....-QEGKS.....L 109 P.....TN.....VYVGNT.....-ATGQLINSVGAGDSMVAGFVGTY.....-LATND.....Y 110 G.....ND.....VTAFPVld...QNQEEIVDTNGAGDAFVGGFLSQL.....-VSNKP.....L 111 N.....HT.....FYRVNI.....-PTINVLNPVGSGDSTVAGITSAI.....-LNHEN.....D 112 G.....NE.....EWKIPV.....-VSVKAVDPTGAGDAYRAGFLLAY.....-TREYS.....L 113 P.....EG.....RWRAAP.....-PAHVRGNPTGAGDSAVAGLLSGL.....-VEHLP.....W 114 N.....GI.....QRKIPA.....-MAVQTVDTTGAGDAFVSAILFKL.....-QEERKqv9keV 115 N.....HT.....FYRVNI.....-PTISVLNPVGSGDSTVAGITSAI.....-LNHEN.....D 116 G.....DT.....FYKVDI.....-PRIQVVNPVGSGDSTVAGISSGL.....-LHKES.....D 117 N.....DK.....FYRVII.....-PKIQVVNPVGSGDSTIAGLTKGL.....-NDGET.....D 118 P.....EK.....QPIHFP.....ALSKTASDVTGAGDTVISIIASSL.....-ATGYS.....L 119 E.....KG.....EVHEVR.....GLSAKAIDTTGGGDAFNAGFLYGF.....-LSGWD.....V 120 R.....EG.....VWLIRS.....KEEIDTSHLLGAGDAYVAGMVYYF.....IKHGAN.....F 121 -.....-N.....GIQVPG.....-YKVNPVDTTGAGDAFTAALLVGImkvr.EITNEN.....L 122 P.....SG.....SVTHPG.....-FAVDPVDTTGAGDAFAAGFVAVV.....-LDGGD.....H 123 P.....NK.....APLHMP.....TQAQEVYDVTGAGDTVIGVLAAGN.....-----T.....L 124 R.....GQ.....VSHFPA.....-RPVVAVDTTGAGDAFVAGLLAGL.....AAHGIPdnlaaL 125 N.....GK.....LYQVIP.....-PKVQERNDTGAGDVFVGAFIAGL.....-AMNMP.....I 126 D.....AG.....TWFGTA.....-RVDAVRSNVGAGDSSLAGFL---.....-VAGGT.....G 127 G.....ND.....VTAFPVld...QNQEEIVDTNGAGDAFVGGFLSQL.....-VSNKP.....L 128 G.....SK.....EVLIPS.....-FPVEPVDTTGAGDTFNAAFAVAL.....-AEGKD.....I 129 D.....D-.....VIKIDA.....-IPREAVDPTGAGDSYRAGFMRAY.....-LRGAD.....L 130 G.....VS.....CGKIKA.....-TEVDVKNVTGAGDSFVAGLGYGY.....-MNKMP.....I 131 Aa....GG.....VVRVPS.....-VKVDAVDTTGAGDAFTAALAWRL.....-GTGES.....L 132 N.....GK.....LYQVIP.....-PKVQERNDTGAGDVFVGAFIAGL.....-AMNMP.....I 133 G.....AE.....RVRVGA.....SVLEQVVDTTGAGDLYAAGFLFGY.....-TSGRS.....L 134 Gav6riED.....APTFPG.....-ERVEVLNVLGAGDAFLSGLLSGL.....-LRGKG.....W 135 A.....EG.....AWQARP.....-PAVEVASTVGAGDSLLAGMLHGL.....-ASGWP.....A 136 K.....DE.....AYTVEG.....FKVKHVVDTVGAGDGFAVGVISAI.....-LEGIS.....V 137 G.....GD.....QWSIPV.....-VSVKALDPTGAGDAYRAGFLLAY.....-TREYS.....L 138 G.....KN.....HGEVPA.....-FKVNVRDTTGAGDSFVAGFLAQA.....LTHGENlf7hlS 139 P.....NQ.....EPYHLP.....TVAKEVFDVTGAGDTVISVLATTL.....-ADGCS.....F 140 I.....SG.....ESGWSA.....PIKTNVINVTGAGDAMMAGLASCW.....-VDGMP.....F 141 G.....EE.....VEIIES.....-IKIKSIDSTGAGDAFVGAFLYKL.....-SEALEa10nkI 142 P.....GQ.....LTAIPT.....-PKIQAVDTTGSGDAFAGALVAKL.....-SEGAG.....L 143 K.....AA.....VRHQPG.....-FTVEVVDTTGAGDVFHGALAFGL.....-ASGYA.....I 144 D.....GV.....YEEVSA.....-SPIEVADTVGAGDAFSAGFLYAY.....-LSGNG.....A 145 A.....TG.....ITDIAT.....-PTVQAVDTTGAGDAFAGAFCARL.....-IKGDS.....L 146 N.....GG.....RQHQPA.....-FKVDVVDTTGAGDVFHGALAVAL.....-ATSGD.....L 147 K.....SS.....VSVAPA.....-FKVEVVDTVGCGDSFVAAIALGY.....-IRNMP.....L 148 G.....KD.....REIIPS.....-IPVTSIDSTGAGDAFVGAALYQLan9sv------da6vkL 149 E.....NG.....QPHFSN.....RYEIHIVDRVGAGDSFAGALIYGS.....-LMGFD.....S 150 N.....GG.....RQHQPA.....-FKVDVVDTTGAGDVFHGALAVAL.....-ATSGD.....L 151 N.....GG.....RQHQPA.....-FKVDVVDTTGAGDVFHGALAVVL.....-ATGGD.....L 152 G.....SK.....EVLIPS.....-FPVEPVDTTGAGDTFNAAFAVAL.....-AEGKD.....I 153 N.....ET.....VVDVPS.....-YNVNPLDTTGAGDAFMAALLVGIl....KLKGLD.....L 154 K.....DK.....QTIVPS.....-ISIQQVDTTGAGDAFVGAMLYQIak7mfLHNFEG.....L 155 K.....DK.....KIEIPC.....IKAGKVIDPTGAGDSYRAGFLSAY.....-VKGYD.....L 156 A.....NL.....KVEVAS.....-ERVEVVDTVGAGDTFDAGILASLk12vaSLSEEQ.....I 157 N.....GH.....KVEVAS.....-ERVEVVDTVGAGDTFDAGVLASLk12vaSLTDEA.....I 158 A.....NL.....KVEVAS.....-ERVEVVDTVGAGDTFDAGILASLk12vaSLSEEQ.....I 159 I.....SG.....ESGWSA.....PIKTNVINVTGAGDAMMAGLASCW.....-VDGMP.....F 160 G.....AE.....AVLAIP.....-PATPIASTVGAGDAMVAGLIHAA.....-TLGLD.....L 161 N.....DE.....QVQVES.....-FRVEPVDTTGAGDTFNGAFAVAL.....--GGGT.....V 162 P.....NQ.....EPYHLP.....TVAKEVFDVTGAGDTVISVLATAL.....-ADGRS.....F 163 G.....ID.....YWFCSA.....-PTVDLVSSACAGDAALAAFLSQW.....-LSTGE.....V 164 P.....EK.....TYDIPP.....AHERRVVDPTGCGDAFRAGLIYGI.....-QGGYD.....W 165 G.....ID.....YWFCSA.....-PTVDLVSSACAGDAALAAFLSQW.....-LSTGE.....V 166 R.....DG.....KKVLIP.....APKVNVIDETGAGDVFNAALSVYL.....-EKGYD.....L 167 D.....EA.....SIFVPA.....-YKVSPVDTTGAGDAFVSALLVGLla6kqKLEESD.....M 168 En....GN.....VYEIRG.....-LSAKAIDTTGGGDSFDAGFIYGY.....-LNGWD.....V 169 P.....EQ.....GGVWIPsqk..LEQREIIGSVGAGDAFCAGFLYGC.....-HERWT.....L 170 E.....GK.....EPQFVPs....CPVDKVVDPVGAGDGFAAGVLASL.....-LEGKS.....M 171 K.....DG.....EQFLLT.....APAHTTVDSFGADDGFMAGLVYSF.....-LEGYS.....F 172 P.....DQ.....TLTVPA.....IEIDDLVDTTGAGDLYAAGFLYGY.....-TKDRS.....L 173 G.....DM.....TMKVPA.....VAGITAIDTIGAGDNFASGFIAAL.....-LEGKN.....L 174 Gpi6dlED.....GIVGKG.....-FPIEIYNVLGAGDAFMSGFLRGW.....-LGGED.....H 175 G.....DM.....TMKVPA.....VAGITAIDTIGAGDNFASGFIAAL.....-LEGKN.....L 176 Eai6tlDE.....GLTVSG.....-VRVKVLNVLGAGDAFMSGLLRGY.....-LNDEG.....W 177 K.....DG.....EQFLLT.....APAHTTVDSFGADDGFMAGLVYSF.....-LEGNN.....F 178 P.....NQ.....PAFHLA.....TEAKEVFDVTGAGDTVISVLATGL.....-ADGRS.....F 179 K.....GE.....AIYIPP.....-SPCVPVDTCGAGDAYASGILYGI.....-LRGVSd....L 180 K.....GE.....AIYIPP.....-SPCVPVDTCGAGDAYASGILYGI.....-LRGVSd....L 181 K.....DG.....EQFLLT.....APAHTTVDSFGADDGFMAGLVYSF.....-LEGYS.....F 182 K.....GE.....AIYIPP.....-SPCVPVDTCGAGDAYASGILYGI.....-LRGVSd....L 183 R.....CSs49lvIVTAEK.....IPSSELIDTTGAGDAFTGALLYGL.....-CTGMA.....L 184 S.....EN.....CIQVVP.....-PALKSQSTVGAGDRLVGAMTLKL.....-AENAS.....L 185 N.....GQ.....LHEISA.....YPVEKVVDTTGAGDQYAAGFLFGL.....-SQGRP.....L 186 L.....EM.....AEILIP.....AYKAQVVDSTGCGDSYCAAFIMGL.....-TKGWD.....L 187 K.....DR.....KVTVPS.....-ERVTVVDTVGAGDTFDAGILASL.....K-----.....- 188 Qn....GK.....VYEVRG.....-LSAKAVDTTGGGDSFNAGFIYGF.....-LNGWD.....V 189 P.....DE.....ARHIAT.....-QAREVFDVSGAGDTVIATFALAL.....-ASGAD.....P 190 P.....DE.....SHELPA.....-LPAAVVDVTGAGDAMLAAFLAGL.....-VAGLT.....P 191 G.....EN.....EGKIPA.....-FAVSVVDTTGAGDSFLAGFIHQLse7hnLNDAET.....A 192 R.....NQ.....PPIHLP.....ATAIEVFDVSGAGDTVAATLALAV.....-AAGAS.....L 193 G.....TE.....IVHVPS.....-IAVDVVDTTGAGDTFNGALAVAL.....-SEGET.....L 194 R.....DQ.....RLIARP.....-PRLAHGSSVGAGDAMVAGLAAAS.....LDAATT.....L 195 G.....SE.....V-MVEA.....-LETSCRDTTGAGDAFNAGFLYAW.....-LSGHG.....L 196 G.....EK.....MYETRQ.....YQITDIVDRVGGGDSFMGGLIYGL.....LKYPED.....D 197 G.....DM.....TMKVPA.....VAGITAIDTIGAGDNFASGFIAAL.....-LEGKN.....L 198 Q.....TAdg7vhEVGVPV.....VAAEKIVDTNGAGDAFVGGFLYGL.....-SQGKT.....V 199 K.....GNp42lfAMHFPT.....-IPAKVKKLTGAGDCLVGGTVASL.....-SDGLD.....L 200 P.....ED.....TELVDAv....LPEGTVVDTTGAGDTFTAAFAHAV.....-LSGLP.....L 201 K.....GNp40lfAMHFPT.....-IPAKVKKLTGAGDCLVGGTVASL.....-SDGLD.....L 202 Q.....TAdg7vhEVGVPV.....VAAEKIVDTNGAGDAFVGGFLYAL.....-SQGKT.....V 203 Q.....TAdg7vhEVGVPV.....VAAEKIVDTNGAGDAFVGGFLYAL.....-SQGKT.....V 204 P.....EG.....TLFQPA.....-LPTLVADTVGAGDASMGGWLASL.....-LTRPEam...P 205 Q.....TAdg7vhEVGVPV.....VAAEKIVDTNGAGDAFVGGFLYGL.....-SQGKT.....V 206 Rq....HG.....TWSQPA.....-QRVVMADTVGAGDTFQAALIAWLt12lqQLTRVQ.....I 207 L.....EM.....AEILIP.....AYKAQVVDSTGCGDSYCAAFIMGL.....-TKGWD.....L 208 K.....DI.....RVDVPS.....-FKVEPVDTTGAGDAFMAALLASLfy9ilEFSKEE.....L 209 Pd....GK.....LLHSDA.....FPPPRVVDTLGAGDTFNASVIFSL.....-SQGRS.....V 210 E.....KG.....VKHFPA.....-RARKVYDVTGAGDTVIASITAFK.....-LAGAT.....W 211 Pd....GK.....LLHSDA.....FPPPRVVDTLGAGDTFNASVIFSL.....-SQGRS.....V 212 Q.....QG.....EQVAIPsyw..VEKQNIVSTLGAGDAFCTGVLYGL.....-HHGLP.....L 213 R.....ASk53lfLGTAEK.....IPPEELVDTTGAGDAFIGAVLYAI.....-CAGMP.....P 214 T.....HG.....SWSRPA.....DTALPLRDTVGAGDTFQAATLAYLr12laALSREA.....I 215 G.....S-.....FTHIPA.....-LSLDVADVSGAGDTVIGTLALGL.....-ASGLD.....L 216 Pd....GK.....LLHSDA.....FPPPRVVDTLGAGDTFNASVIFSL.....-SQGRS.....V 217 P.....EK.....TYDIPP.....AHERRVVDPTGCGDAFRAGLIYGI.....-QHNYD.....W 218 R.....ASk52lfLGTAEK.....IPPEELVDTTGAGDAFIGAVLYAI.....-CAGMP.....P 219 K.....EA.....TYFAKP.....-IKGEVKNSVGAGDSMVAGFTGEF.....-MKSQN.....P 220 H.....GQ.....EGAWVPswk..LAQEEIVGSVGAGDAFCAGILYGY.....-HERWP.....L 221 R.....GN.....VLFAPA.....-VPVDAVDTLGAGDAFLSRLACRV.....-LAGVT.....L 222 R.....EG.....RIDRFA.....APKVDVVDTSGAGDVFCGCLAGFL.....-AAGIS.....L 223 D.....KE.....VVHISA.....IGETVATDATGAGDLFASGFLYGL.....-IKGLS.....L 224 Q.....NK.....LLFVSS.....ITPKQVVSTTGAGDTLLAVFLANL.....-ILKVD.....L 225 D.....NTh12gaFTFAKT.....-LTFSVYDRIGAGDAYTSGIIHGE.....-IEEFA.....P 226 Hes...PE.....VQFLPA.....IQNVSVVDTTGAGDTFLGGLVTQL.....-YQGET.....L 227 G.....SK.....FYNAKK.....-YDIHVVDNIGGGDAFAASLIYAI.....-TSNFS.....N 228 Hes...PE.....VQFLPA.....IQNVSVVDTTGAGDTFLGGLVTQL.....-YQGET.....L 229 A.....EG.....AWTATS.....-PKIDVVSTVGAGDCALAGFVMAR.....-SQKKT.....L 230 Kksk..DM.....CTHVPA.....SDVPHLADPSGAGDAFMGSLAYHIa....RFPKLS.....T 231 S.....AG.....RVDLPT.....-VPVEVADTVGAGDSLCAGLLVSA.....-TERPDal...W 232 G.....DR.....EVTVKP.....-VSTKVVDTTGAGDAFNAGFLYGY.....-LKGKD.....I 233 K.....KG.....SFQSPA.....-FPAKVADTTGAGDAFAAGFIYGF.....-IKNYP.....L 234 K.....DH.....TVTVMP.....-EKVEVVDTVGAGDTFNAGILASLhe9ka------ai9daI 235 G.....AE.....VASAGI.....-RAVEVVDTTGAGDSFIAGFIAAR.....-LEGRA.....L 236 N.....YV.....EELAPPg10raQRVEQLVDATGAGDAFVAGFLHAW.....-LEKRS.....L 237 An....GN.....YYEMSS.....YKQDKVVDTLGAGDSFMAGFIYAT.....LKARRS.....L 238 G.....DR.....VYHQPI.....-VEADIIDTLGAGDSFIAGFLTAF.....-CVKQD.....I 239 G.....KQ.....VVQVAA.....TGESNAVDATGAGDLFASGFLYGL.....-VKGLA.....L 240 E.....NE.....ECYCEP.....YKVQTVLDTTGAGDVFDAAFNYAY.....-VQGYS.....I 241 -rt...NE.....QGHVPT.....-TKVKVADSTGAGDSFFSAVISEL.....-MKEHS.....I 242 A.....DH.....SLEMKV.....-EDAGAIDTTGAGDAFAAGFMSEW.....-LRGYE.....P 243 G.....GR.....RTAVPA.....-LPVDVVEPVGAGDAFAAGWIHGA.....-LVGLD.....E 244 -.....-G.....EVYVPG.....-NGISYPHSIGLGDLFDIVFVHHL.....-PLGKS.....K 245 Q.....QQ.....LLFMEA.....IPPQQLVSTTGAGDTLLGVFLANL.....-LLDKD.....P 246 Q.....NK.....LLFVSS.....ITPKQVVSTTGAGDTLLAVFLANL.....-ILKVD.....L 247 K.....GNp42lfAMHFPT.....-IPAKVKKLTGAGDCLVGGTVASL.....-SDGLD.....L 80 290 300 310 | | | | 1 LEMAKFGFASALAATRRKEKY...MPDLEAIKKEYDHFTVERVK 2 REALLFANACGAITVTERGAIpa.MPSMDAVQDLL--------- 3 REAIFFANVCAALTVTGRGGIps.LPTQDAVRQT---------- 4 EEAIKFANACGAITATKKGAIps.LPTEVEVLKLM--------- 5 EHTLRLATAVAALAVSQSNVG...ITDRPQLAAMMARVDLQP-- 6 RKVLRFANACGAITTTKKGAIpa.LPTDIEALSFLKDQ------ 7 AAAIRFGQAAAAISVTRLGAQts.IPSREEVE------------ 8 EHTLRLATAVAALAVSQSNVG...ITDRPQLAAMMARVDLQP-- 9 RKVLRFANACGAITTTKKGAIpa.LPSDAEVRSFLE-------- 10 RKVLRFANACGAITTTKKGAIpa.LPSDAEVRSFLE-------- 11 TETLAFATAVSAFAVSQSNVG...VSDLSLLDPILEKVQITMI- 12 DVAVRFAHAAAAIAVTRPGAQps.IPWRAEIDSFLQ-------- 13 EETIKIAAALSTSVVMKEGTG...AGTIEEVNALKDKIEIERIE 14 VSSLKKASLYAAHSITRPGTQka.YASIDEFEAF---------- 15 DEAIRFGQAAAAISVTKKGAQss.IPTRQETLEFL--------- 16 SASIRSAANLAALSVTRHGTQss.YWKLDEIRQQY--------- 17 REALMFANACGALTVKVRGAIpa.LPTKEAV------------- 18 EEAFRLGVTSGSATAFSEE--...LGTEEFVQQLLPEVKV---- 19 HQAVIWGAAAGALAATKLGAQts.LPDKLTFEAFLK-------- 20 ISSIRFGNKVSSIAVQRKGAQps.IPYLKEVLEIY--------- 21 LDAVKWANGCGALATTQKGAMta.LPNQ---------------- 22 EHTLRLATAVAALAVSQSNVG...ITDRPQLAAMMAKVDLKP-- 23 PQAMRLGGASASIVISKHSCSda.MPTRAEISAFME-------- 24 EKTLAFATALSSLAVSQSNVG...ITDLTLLNPILEKIKI---- 25 ETALKYGSASASIVVSKHSSSda.MPSVEEIEALIEK------- 26 EKAFRFAVACGTATSFSED--...IGELNFIEEIYNRLVIE--- 27 KEILRFSIACGAASVSTEGTE...ACSLEDVKELLKSVVIE--- 28 EAALKKAALFAAFSVTGKGTQss.YPSIEQFNEF---------- 29 KEALAFANACGAVCTTQKGAIpa.LPTPADAQKLMK-------- 30 MDALEFGSASAAMLVASHSCSed.MPTVEAIKEFIKK------- 31 ETALKYGSASASIVVSKHSSSea.MPTAEEIEQLI--------- 32 AEAISNANACGAMAVTAKGAMta.LPFPDQLNTFLS-------- 33 EAAMKKAVLFAAFSVTGKGTQss.YPSIEQFNEY---------- 34 DFAVQQAQHSGAAATTAKGAMta.LPYAKDL------------- 35 EEMVRFGVAAGSAATLNQGTR...LCSHDDTQKI---------- 36 EEMVRFGVAAGSAATLNQGTR...LCSHDDTQKI---------- 37 EEACFFANAAAGVVVGKLGTS...TVSPIELEN----------- 38 EEACFFANAAAGVVVGKLGTS...TVSPIELEN----------- 39 EKASLYATIVASIKVSRLGSNa..APSHEEVVEK---------- 40 EEACYFANAAAGVVVGKLGTS...TVSPIELEN----------- 41 RALLTKANVLGMLNAQEKTTG...HVNMANYDKLYQSIKVK--- 42 EEACYFANAAAGVVVGKLGTS...TVSPIELEN----------- 43 EEACYFANAAAGVVVGKLGTS...TVSPIELEN----------- 44 VKSFAAGVATGGATAFSTD--...LAEKDLINELLPQVKITKI- 45 EEMVRFGVAAGSAATLNQGTR...LCSRDDTQKI---------- 46 EEMVRFGVAAGSAATLNQGTR...LCSHDDTQKI---------- 47 REALKFSNACGAICTTKKGAIpa.LPTV---------------- 48 ETALKFGSAAASIVVSKHSSSda.MPTADEIKAL---------- 49 EDAIRFATFVAALTVTKEGAQts.LPYKEEVEKFIK-------- 50 REIISYGNKVGALTCTNYGAIda.IPNEEDL------------- 51 YERLLFANAAAAIKVTRPSARa..SPRYDEVVAFLE-------- 52 VKAFAAGVATGGATAFSTD--...LAQKELIDELLPQVKITKI- 53 ETALKYGSAAASIVVSKHSSSda.MPTADEIKALI--------- 54 ATSATWANACGAFAVSRLLCApe.IPTWTELQYFLE-------- 55 EETVRLSVAFAACKLQRIGPH...LPPPQQVRERA--------- 56 VEIIKQANACGALATTAKGAMsa.LPNKQQLDAF---------- 57 IEALKWGVACGTATAFSDD--...LATIAFIKETYHKVEVE--- 58 EQCARLATAFSMCRLESGDAR...RITPEGVR------------ 59 PTTLKYANACGAFAVSRHGCTpa.YPSWEELQYFF--------- 60 EEMLKRSNFIAAVSVQATGTQss.YPYKK--------------- 61 IASFKNGIASGSASAFSLD--...LALAEDVNKLLPIIKIEKY- 62 PDAARRATSFSVSTITRLGAH...LPARDELAGYAAQVT----- 63 EDMLNRSNFIAAVSVQAAGTQss.YPYKK--------------- 64 EPTLTLAQTCGALATTAKGAMta.LPYQR--------------- 65 DQALARAGAAGSLACLKPGAQpa.IPLAKDVDQALQE------- 66 VEAFKWGVACGTATTFSDD--...LATAEFIKETYGKVEVE--- 67 VEAFKWGVACGTATTFSDD--...LATAEFIKETYGKVEVE--- 68 EKLLKKANTLGMLNAQEKLTG...HVNLENYDNLYQQIEV---- 69 LLAFRQAIACGTSKAFSDD--...MPSRAFLEEIYKKVNISEV- 70 IEALKWGVACGTATAFSDD--...LATIAFIKETYHKVEVE--- 71 EEMVRFGVAAGSAATLNQGTR...LCSHDDTQKI---------- 72 SSAIQWANGCGALATTQKGAMta.LPTQTELLRF---------- 73 RALLTKANVLGMLNAQEKTTG...HVNMANYDKLYQSIKVK--- 74 EHTLRLATAVAALAVSQSNVG...ITDRPQLAAMMARVDLQP-- 75 REAIKKALAVAALYVTRRGAQrs.MPSSWAVDEFLNSQSILEL- 76 HDCVRYGSAAGAIAVTRVGAGaa.APTAREVEEL---------- 77 TECIRAGHYAASVIIRRTGCT...FPEK---------------- 78 LEALKWGVACGTATAFSDD--...LASIDFIKETYEKVEVEK-- 79 VEAIQFGLAAAAVSVTRLGAQps.IPFRSE-------------- 80 VEIGKFANAVAAIVITRVGGVda.MPVLDEVEMFLS-------- 81 EDSFKFGVAAGTATALKGN--...LCEFQDVKKMLCQIRVEDI- 82 EKIIALGTACGTANAMIKETG...WVETKTVKDIMKKVKLE--- 83 EKAFQQAVACGTATAFDED--...LATRDAIEKIKSQVTI---- 84 TECIRAGHYAASVIIRRTGCT...FPEKP--------------- 85 TECIRAGHYAASVIIRRTGCT...FPEKP--------------- 86 SDSIRLAVVASHLSIQKFGAQgg.MPKLSEVKAKLKELE----- 87 EEAVIFGTAAAAISVTRLGAQss.IPAREEVEAFLK-------- 88 EVSAKLGLAAASLTISSPYTVnp.FLNEN--------------- 89 PTSLKFANACGAFAVSRHGCTpa.YPSWEELQFFLQ-------- 90 RALLTKANVLGMLNAQEKTTG...HVNMANYDKLYQSIKVK--- 91 VAAIQYASAFASLAVEQVGASs..MPQHLQVL------------ 92 ADLLKHAMTLGMLNAQETMTG...HVNMTNYETLNSQIGVK--- 93 EECLRFAAAAASLCVQVKGAIps.MPDRKSVLKLL--------- 94 EECLRFAAAAASLCVQVKGAIps.MPDRKSVLKLL--------- 95 TECIRAGHYAASVIIRRTGCT...FPEKP--------------- 96 EKAFQYGVATGSATAFSAD--...LCEKEKVEELLSQVI----- 97 LQAVRFACAVAGISVTRPGTAps.MPTLQEVEAL---------- 98 IKSVRLGNAAGAAMLLTPGTA...ACNRDDVERFF--------- 99 EEACFYANIGASIVIQKIGTE...TLNINELNSVL--------- 100 AEVIRFAAAVGALAVTRKGAFaa.MPSVDEVHSLI--------- 101 ESLLRFATALSALAVTQVGVG...LGDREQLNTLQQQIQV---- 102 SKAVSVAIMLGTYVASKPGSV...PEYSEELRK----------- 103 TECIRAGHYAASVIIRRTGCT...FPEKP--------------- 104 EKAFQQAVACGTATAFDED--...LATRDAIEKIKSQVTI---- 105 AHALALASATGADVAGSAG--...LGKLQRTEELLQQIQV---- 106 EQCARLATAFSMCRLESGDAR...RITPEGVR------------ 107 AELLIKANVLGMLNAQEKMTG...HVNMANYQALYDQLIVK--- 108 EDAVPFAVAAGSATAFSDG--...FCTREEVERLQQQL------ 109 QEAMLTSICAGSATAFSQG--...IADKLLVESLKQQIKIRT-- 110 TECIRAGHYAASVIIRRTGCT...FPEKP--------------- 111 HDLLKKANTLGMLNAQEAQTG...YVNLNNYDELFNQIEVL--- 112 PTCGKIGSTVASFAVQSRGCQts.LPTWEEMKSRY--------- 113 PDRLARAVALSAATVLAPVAG...EFDRAAYEELL--------- 114 EQMARFASVSGGLAAATKGAMta.LPTLEKVNDILR-------- 115 HDLLKKANTLGMLNAQEAQTG...YVNLNNYDDLFNQIEVL--- 116 AELLIKANVLGMLNAQEKMTG...HVNMANYQALYDQLIVK--- 117 ENVLKIANTLGMLNAQEHITG...YVNMDNYKNLFEKIKV---- 118 EEACFYANVGASIVIQKIGTE...TLTINQLN------------ 119 VNSAKLGMLLAYLTVQEVGARsa.VRPLDEIKKIAQEL------ 120 LEMAKFGFASALAATRRKEKY...MPDLEAIKKEYDHFTVERV- 121 EKIGKFANLVAALSTLKRGAWs..VPKVEELLKYKEAR------ 122 ERALEFGNACGALAAQHEGARt..APTRADAASFL--------- 123 EEACYFANAAAGVVVGKLGTS...TVSPIELEN----------- 124 APDLALAQTCGALATTAKGAMta.LPYKDDLQ------------ 125 TETLKVATGCSASKVMQQDSS...SFDLEAAGKLKNQVSIIQL- 126 PGALASAVAHGAAAVQLPGSV...MPTPHDL------------- 127 TECIRAGHYAASVIIRRTGCT...FPEKP--------------- 128 EAALRFANRAASLSVCSFGAQgg.MPTRNEVEEL---------- 129 KTCGRFASAVASFIVEDEGTQtn.IPDTGE-------------- 130 EDIVKFAMTMSNITISHEETI...HPDM---------------- 131 ADAAAYAARVGAAAVTKAGAQes.YPTAAEAE------------ 132 TETLKVATGCSASKVMQQDSS...SFDLEAAGKLKNQVSIIQL- 133 EECSKLGNLAAGIVIGQIGPRp..-------------------- 134 AESARIANACGAIVVSRHACSaa.MPTPAELAHW---------- 135 ERVLRQATAIASLAVTQFEFG...IGDPQRLARIEAGV------ 136 KEAVRRGNAVGALAVMSEGDNdg.YPTHEELEKFL--------- 137 PTCGKIGSTVASFAVQSRGCQts.LPTWEEMKSRY--------- 138 CQAVTYASAIGALTTLHPGA-...-------------------- 139 EESCYLANVAAGIVVGKLGTS...TVSTVELEN----------- 140 AESVRFAQGCSSMALSCEYTN...NP------------------ 141 KENVRFANKVGAIVCTKLGAIss.LPSLSEV------------- 142 IEAATFAARVGAYAATRPGAQas.-------------------- 143 EEAVRFASGVAALKCTRPGGRag.IPDCEQTRSFL--------- 144 SKALSIATTLGTYVASKPGAV...PEYSEELIEEL--------- 145 IDAATHAARVGAYSVQTAGAQ...-------------------- 146 AESVRFASGVAALKCTRPGGRag.IPDCDQTRSFL--------- 147 VNTLTIANAVGAATAMGCGAGrn.VAKRHQVVDLMK-------- 148 REIVAFANKVGALVCTKIGAIda.LPSLDE-------------- 149 QKKAEFAAAASCLKHTIPGDFv..VLSIEEIEKL---------- 150 AESVRFASGVAALKCTRPGGRag.IPDCDQTRSFL--------- 151 AESVRFASGVAASKCTRPGGRag.IPDCDQTRSFL--------- 152 EAALRFANRAASLSVCSFGAQgg.MPD----------------- 153 LKLGKFANLVAALSTQKRGAWs..TPRKDELLKYKE-------- 154 TTFISFANKVGALTCTNYGAIss.LPSLTDV------------- 155 EKCGLIGAATASFVVEAKGCQtn.LPTWDKVVERLEK------- 156 RKALALGAKAAAVTVSRAGAN...PPF----------------- 157 RQALTLAAKAAAVTVSRAGAN...PPWRHE-------------- 158 RKALALGAKAAAVTVSRAGAN...PPF----------------- 159 AESVRFAQGCSSMALSCEYTN...NP------------------ 160 AETARLATAFSLGALGEIGPH...LPPPERLAALARTVTVK--- 161 KEAVRFANAAAALSVQSFGAQgg.MPTKAQVQSFLQ-------- 162 EESCYLANVAAGIVVGKLGTS...TVSTVELEN----------- 163 EYALSLASATGADVASSAG--...LGQLAAIETLLSQIHVR--- 164 LTIGRMGNLMGALKVEHPGTQnq.RFDFAEFNDQFK-------- 165 EYALSLASATGADVASSAG--...LGQLAAIETLLSQIHVR--- 166 ETAVEYANKVAALSVTKIGAL...GPKLDEVVRFLEE------- 167 FLLGKFANLVAGLSTQKRGAWs..VPRREELEKYEEGRKI---- 168 KDSAKLGMLLAYLTVQKVGARsa.VIPLDEVKKIAKE------- 169 TESIKLAHACARASLLCANAIdg.AKTLEELQT----------- 170 EEAVSVGTQIGALVVMAKGDMeg.LPEREQLEA----------- 171 RDSARFAVACAAI--------...-------------------- 172 EDCARLGSLAAGLIIQQMGPR...-------------------- 173 RECARFANATAAISVLSVGATtg.VKNRKLVEQLLEE------- 174 ATAATWANACGAFAVSRLLCApe.YPTFEELQFFLK-------- 175 RECARFANATAAISVLSVGATtg.VKNRKLVEQLLEE------- 176 PQACRYANACGALVVSRHGCApa.MPSKIELDNYL--------- 177 RDSARFAMACAAI--------...-------------------- 178 EEACYLANVAAGIVVGKLGTS...TVSTVELEN----------- 179 KGMGDMAATIAATVVGQQGTR...LRV----------------- 180 KGMGDMAATIAATVVGQQGTR...LRV----------------- 181 RDSARFAVA------------...-------------------- 182 KGMGDMAATIAATVVGQQGTR...LRV----------------- 183 EEMLTFASRV-----------...-------------------- 184 EEMVRFGVAAGSAATLNQGTR...LCSHDDTQKI---------- 185 PICGQLGSLAAAEVIDHYGPRp..QVSLRE-------------- 186 ATSGRFASAAASLVVSGLGSDag.IIDFEHTLKVMN-------- 187 ---------------------...-------------------- 188 VSSAKLGMLLAYLTVQKVGARsa.VIPLEEVKKKANE------- 189 VAAASIANAAGGVVVGKRGTA...RLTVEEL------------- 190 LHAAREGHAAAALTVESPLTV...VPD----------------- 191 KRIITYASAVGALTTTKAGAIas.QPTAMEVETFL--------- 192 AQAAQLANLAGGLVVAKLGTD...VVTAAE-------------- 193 QKAIRFANIAGGLSVTKLGAQgg.MPTRDRVR------------ 194 EQCARLATAFSMCRLESGDAR...RMTPEGVRRAATDVVIE--- 195 EVSCLFGNYMASRCIEGYGATss.LPGREALE------------ 196 QNALDFAVAASCLKHTIKGDAn..LVKVEEVEKLM--------- 197 RECARFANATAAISVLSVGATtg.VKNRKLVEQLLEE------- 198 KQCIMCGNACAQDVIQHVG--...-------------------- 199 IQSLAVGIASAKAAVESDDNV...PPE----------------- 200 TQAARVANAAGALAATAVGAQsk.-------------------- 201 IQSLAVGIASAKAAVESDDNV...PPE----------------- 202 KQCIMCGNACAQDVIQHVG--...-------------------- 203 KQCIMCGNACAQDVIQHVG--...-------------------- 204 ASHLEFSAASAAAVCARQGAY...APTREEI------------- 205 KQCIMCGNACAQDVIQHVG--...-------------------- 206 DAMLGFAIRAAALTCGKTGPD...LPYRQ--------------- 207 ATSGRFASAAASLVVSGLGSDag.IIDFEHTLKVMN-------- 208 KELGSFANLVAALSTTKRGAWs..VPSLEEVL------------ 209 QEALRFGCQVAGKKCGLQG--...-------------------- 210 EECCELGNVCGGIVVGEFGTA...TVTPEKL------------- 211 QEALRFGCQVAGKKCGLQG--...-------------------- 212 VEVLKLGHGLAYFNLFSMSATgg.AVSYGELQTFIKQ------- 213 EKMLPFAAQVAGCSCRALGARtg.LP------------------ 214 DAMLAFAIRAAAVTCSRVGPD...LP------------------ 215 VTSTRIANLAANTVCQEVGAV...PVRPD--------------- 216 QEALRFGCQVAGKKCGLQG--...-------------------- 217 LTIGRMGNLMGALKVEHPGTQnq.RFDFAEFNDQFK-------- 218 EKMLPFAAQVAGCSCRALGARtg.LP------------------ 219 IEALKWGVACGTATAFSDD--...LATIAFIKETYHKVEVE--- 220 NDCIQLAHACARANLLCANAIdg.AKPLAE-------------- 221 NEAARDGAQYAAHICGTRGA-...-------------------- 222 AAAARIAVRAAAISVGRPGTLgs.CPDRQEMKILME-------- 223 EECCKVGSCSGGSVIRALG-G...EVTPENWQWMHKQLQLKGL- 224 KTALIKATNYASATISKLGV-...-------------------- 225 EKAVSFASAAGMLAHTIVGDTp..MSSE---------------- 226 STAIKFSTLASSLTIQRKGAAes.MPLYKDV------------- 227 QEIIEFATAGSCLKYSMNGDVn..LSTVDEIIKLMN-------- 228 SMAIKFSTLASSLTIQRKGAAes.MPLYKDV------------- 229 EESLLNAVSYGSTAASLPGTT...IPRPDQL------------- 230 EHHISAAHSCAAYSMGRRGTQps.FPGK---------------- 231 TEHLRFGLGAASVTCAHAGAY...APTREEV------------- 232 EECGRLGNFVAAKCIEKYGAR...-------------------- 233 EVCLTLGNFCGAYNVERVGARn..FPSKSTIDEFL--------- 234 RKALALGAKAAAVTVSRAGAN...PPWRHE-------------- 235 AACLEAGRDLAADTCTHVGGF...-------------------- 236 GECIRMASSVAAKVVTQVGCN...-------------------- 237 AEAVDFANRVASHKITGFG--...-------------------- 238 TYALRQAAETAAKTCGVYGAFgyg-------------------- 239 EECCKVGACSGGSVVRALG-G...EVRPENWQWMYKQM------ 240 EDTLRFAVTASALKVMRIGGIn..SPTREEVMNAL--------- 241 EDALRLGMRVAGKVIGSHDNGl..-------------------- 242 LECLRGGHRAALKVISRFG--...-------------------- 243 AGCLRLGHLLAGAAMTSLSDV...-------------------- 244 KEILEEAVKCSQILGQKENVT...PFERISFL------------ 245 VGSLKVAVNYASATISK----...-------------------- 246 KTALIKATNYASATISKLGV-...-------------------- 247 IQSLAVGIASAKAAVESDDNV...PPE-----------------