PFRMAT SS TARGET T0189 AUTHOR 4069-6308-1312 METHOD This file is the result of combining several RDB files, specifically METHOD T0189.t2k.dssp-ebghstl.rdb (weight 1.53986) METHOD T0189.t2k.stride-ebghtl.rdb (weight 1.24869) METHOD T0189.t2k.str.rdb (weight 1.53983) METHOD T0189.t2k.alpha.rdb (weight 0.659012) METHOD These files were combined by translating their predictions into EHL METHOD predictions with tables generated by compare-real, and then combining METHOD those predictions with weights proportional to their mutual information METHOD with the EHL alphabet. The comments from the individual files follow. METHOD METHOD Comments from T0189.t2k.dssp-ebghstl.rdb METHOD ============================================ METHOD TARGET T0189 METHOD Using neural net t2k-5740-IDaaHr-5-15-7-15-9-15-13-ebghstl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 7 (1 EBGHSTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0189.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ METHOD Comments from T0189.t2k.stride-ebghtl.rdb METHOD ============================================ METHOD TARGET T0189 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-ebghtl-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 6 (1 EBGHTL ) METHOD The input amino acid frequencies were determined from METHOD alignment T0189.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ METHOD Comments from T0189.t2k.str.rdb METHOD ============================================ METHOD TARGET T0189 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-str-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 13 (1 str ) METHOD The input amino acid frequencies were determined from METHOD alignment T0189.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ METHOD Comments from T0189.t2k.alpha.rdb METHOD ============================================ METHOD TARGET T0189 METHOD Using neural net t2k-5651-IDaaHr-5-15-7-15-9-15-13-alpha-seeded.net METHOD This is a 4-layer network, with METHOD window units METHOD 5 15 METHOD 7 15 METHOD 9 15 METHOD 13 11 (1 ABCDEFGHIST ) METHOD The input amino acid frequencies were determined from METHOD alignment T0189.t2k-thin90.a2m.gz METHOD with weighted counts, using HenikoffWeight(-1 bits/column, 1) METHOD Counts were regularized to probabilities using METHOD /projects/compbio/lib/recode3.20comp METHOD Total sequence weight for alignment was 188 METHOD METHOD ============================================ MODEL 1 M C 0.88 V E 0.59 L E 0.87 T E 0.92 V E 0.92 T E 0.78 L C 0.59 N C 0.71 P C 0.56 A E 0.49 L E 0.66 D E 0.72 R E 0.73 E E 0.76 I E 0.69 F E 0.61 I C 0.53 E C 0.71 D C 0.78 F C 0.80 Q C 0.87 V C 0.79 N C 0.80 R C 0.71 L C 0.54 Y C 0.51 R C 0.54 I C 0.59 N C 0.61 D C 0.64 L C 0.68 S C 0.77 K C 0.66 T C 0.54 Q C 0.49 M C 0.45 S C 0.68 P C 0.80 G C 0.84 G C 0.74 K H 0.70 G H 0.90 I H 0.95 N H 0.96 V H 0.96 S H 0.96 I H 0.96 A H 0.96 L H 0.96 S H 0.95 K H 0.90 L C 0.56 G C 0.94 V C 0.91 P C 0.73 S E 0.76 V E 0.88 A E 0.92 T E 0.88 G E 0.75 F E 0.59 V C 0.60 G C 0.83 G C 0.77 Y C 0.68 M H 0.56 G H 0.80 K H 0.92 I H 0.94 L H 0.95 V H 0.95 E H 0.95 E H 0.94 L H 0.92 R H 0.90 K H 0.79 I H 0.57 S C 0.66 K C 0.77 L C 0.84 I C 0.80 T C 0.76 T C 0.58 N C 0.58 F E 0.52 V E 0.78 Y E 0.84 V E 0.79 E C 0.49 G C 0.83 E C 0.87 T C 0.74 R C 0.64 E E 0.55 N E 0.69 I E 0.86 E E 0.91 I E 0.93 I E 0.92 D E 0.92 E E 0.88 K C 0.52 N C 0.85 K C 0.91 T C 0.86 I E 0.52 T E 0.84 A E 0.87 I E 0.88 N E 0.82 F E 0.66 P C 0.64 G C 0.82 P C 0.74 D C 0.63 V C 0.49 T H 0.56 D H 0.60 M H 0.59 D H 0.51 V H 0.78 N H 0.83 H H 0.85 F H 0.86 L H 0.86 R H 0.84 R H 0.78 Y H 0.77 K H 0.88 M H 0.87 T H 0.86 L H 0.82 S H 0.64 K C 0.66 V C 0.84 D C 0.83 C E 0.90 V E 0.93 V E 0.93 I E 0.88 S E 0.51 G C 0.77 S C 0.73 I C 0.74 P C 0.78 P C 0.78 G C 0.82 V C 0.85 N C 0.85 E H 0.86 G H 0.93 I H 0.94 C H 0.96 N H 0.96 E H 0.96 L H 0.96 V H 0.96 R H 0.96 L H 0.96 A H 0.96 R H 0.94 E H 0.89 R C 0.67 G C 0.94 V C 0.87 F E 0.67 V E 0.88 F E 0.89 V E 0.84 E C 0.54 Q C 0.85 T C 0.87 P C 0.75 R C 0.60 L H 0.53 L H 0.61 E H 0.66 R H 0.67 I H 0.75 Y H 0.82 E H 0.82 G H 0.82 P H 0.72 E H 0.52 F C 0.65 P C 0.82 N C 0.80 V E 0.80 V E 0.86 K E 0.80 P C 0.54 D C 0.80 L H 0.74 R H 0.91 G H 0.94 N H 0.95 H H 0.95 A H 0.95 S H 0.93 F H 0.89 L H 0.58 G C 0.86 V C 0.88 D C 0.82 L C 0.80 K C 0.85 T C 0.85 F H 0.68 D H 0.73 D H 0.79 Y H 0.93 V H 0.94 K H 0.95 L H 0.95 A H 0.95 E H 0.95 K H 0.94 L H 0.93 A H 0.86 E H 0.69 K C 0.65 S C 0.91 Q C 0.87 V E 0.75 S E 0.91 V E 0.93 V E 0.92 S E 0.85 Y E 0.56 E C 0.80 V C 0.79 K C 0.83 N C 0.67 D E 0.72 I E 0.90 V E 0.91 A E 0.90 T E 0.65 R C 0.84 E C 0.91 G C 0.68 V E 0.71 W E 0.87 L E 0.85 I E 0.73 R C 0.57 S C 0.65 K C 0.71 E C 0.75 E C 0.63 I E 0.51 D E 0.69 T E 0.75 S E 0.70 H E 0.54 L C 0.57 L C 0.69 G C 0.72 A H 0.49 G H 0.70 D H 0.91 A H 0.95 Y H 0.96 V H 0.96 A H 0.96 G H 0.96 M H 0.96 V H 0.96 Y H 0.95 Y H 0.94 F H 0.88 I H 0.74 K C 0.54 H C 0.81 G C 0.92 A C 0.89 N C 0.84 F H 0.92 L H 0.95 E H 0.95 M H 0.95 A H 0.95 K H 0.95 F H 0.95 G H 0.94 F H 0.95 A H 0.94 S H 0.94 A H 0.93 L H 0.92 A H 0.88 A H 0.81 T H 0.66 R H 0.49 R C 0.56 K C 0.73 E C 0.86 K C 0.82 Y C 0.80 M C 0.84 P C 0.88 D C 0.89 L H 0.90 E H 0.93 A H 0.94 I H 0.95 K H 0.94 K H 0.90 E H 0.85 Y H 0.77 D H 0.61 H C 0.56 F C 0.59 T E 0.60 V E 0.74 E E 0.74 R E 0.71 V C 0.58 K C 0.91 END